Introduction

Kenneth did RNAseq on lung primary cells.

That data was aligned by the genome center, we have the preliminary reports:

So ultimately, what is pitavastatin suppressing?

PCA

First two PCs cover 96% of the variance in the data, yay that’s very good

Replicates don’t cluster together so it looks like possible batches are behaving ok

Gene expression programs changes between conditions

Cytokine vs Control

Volcano plots

ensembl baseMean log2FoldChange lfcSE stat pvalue padj ensembl_version protID prot_name gene ENTREZID description gene_biotype
ENSG00000161905 24383.731220 3.341182 0.0760391 43.940325 0.0000000 0.0000000 ENSG00000161905.13 P16050 ALOX15 ALOX15 246 arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] protein_coding
ENSG00000124215 5672.004630 3.725311 0.0585191 63.659786 0.0000000 0.0000000 ENSG00000124215.17 Q9NTY2 CDH26 CDH26 60437 cadherin 26 [Source:HGNC Symbol;Acc:HGNC:15902] protein_coding
ENSG00000197632 8134.727375 2.748470 0.0769638 35.711202 0.0000000 0.0000000 ENSG00000197632.9 E7ERB5 SERPINB2 SERPINB2 5055 serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] protein_coding
ENSG00000188761 1324.570586 3.458512 0.0995078 34.756191 0.0000000 0.0000000 ENSG00000188761.13 Q5TBC7 BCL2L15 BCL2L15 440603 BCL2 like 15 [Source:HGNC Symbol;Acc:HGNC:33624] protein_coding
ENSG00000118515 2632.755859 2.232661 0.0671065 33.270406 0.0000000 0.0000000 ENSG00000118515.12 O00141 SGK1 SGK1 6446 serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810] protein_coding
ENSG00000214711 1144.254049 6.186115 0.1894788 32.648064 0.0000000 0.0000000 ENSG00000214711.10 A8MX76 CAPN14 CAPN14 440854 calpain 14 [Source:HGNC Symbol;Acc:HGNC:16664] protein_coding
ENSG00000131620 731.106344 4.864868 0.1494850 32.544197 0.0000000 0.0000000 ENSG00000131620.18 E9PP68 ANO1 ANO1 55107 anoctamin 1 [Source:HGNC Symbol;Acc:HGNC:21625] protein_coding
ENSG00000172575 654.800975 3.772937 0.1169320 32.266066 0.0000000 0.0000000 ENSG00000172575.14 H0YKP8 RASGRP1 RASGRP1 10125 RAS guanyl releasing protein 1 [Source:HGNC Symbol;Acc:HGNC:9878] protein_coding
ENSG00000007171 1600.098037 7.173616 0.2286440 31.374611 0.0000000 0.0000000 ENSG00000007171.19 A0A8V8TKX9 NOS2 NOS2 4843 nitric oxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:7873] protein_coding
ENSG00000138131 3844.508213 2.684943 0.0865867 31.008724 0.0000000 0.0000000 ENSG00000138131.4 Q96JB6 LOXL4 LOXL4 84171 lysyl oxidase like 4 [Source:HGNC Symbol;Acc:HGNC:17171] protein_coding
ENSG00000166348 3892.551650 1.789273 0.0586073 30.529864 0.0000000 0.0000000 ENSG00000166348.20 A0A8I5KRV2 USP54 USP54 159195 ubiquitin specific peptidase 54 [Source:HGNC Symbol;Acc:HGNC:23513] protein_coding
ENSG00000242550 1716.806799 2.868059 0.0945425 30.336184 0.0000000 0.0000000 ENSG00000242550.7 P48595 SERPINB10 SERPINB10 5273 serpin family B member 10 [Source:HGNC Symbol;Acc:HGNC:8942] protein_coding
ENSG00000174485 2299.262733 1.610739 0.0533544 30.189411 0.0000000 0.0000000 ENSG00000174485.16 H3BTW5 DENND4A DENND4A 10260 DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321] protein_coding
ENSG00000206073 4195.872945 2.807949 0.0933300 30.086229 0.0000000 0.0000000 ENSG00000206073.11 P48594 SERPINB4 SERPINB4 6318 serpin family B member 4 [Source:HGNC Symbol;Acc:HGNC:10570] protein_coding
ENSG00000178934 799.404442 2.805439 0.0939907 29.848052 0.0000000 0.0000000 ENSG00000178934.5 P47929 LGALS7 LGALS7B 653499 galectin 7B [Source:HGNC Symbol;Acc:HGNC:34447] protein_coding
ENSG00000182606 5201.849397 1.474937 0.0496666 29.696784 0.0000000 0.0000000 ENSG00000182606.17 Q9UPV9 TRAK1 TRAK1 22906 trafficking kinesin protein 1 [Source:HGNC Symbol;Acc:HGNC:29947] protein_coding
ENSG00000136826 1576.393093 1.810673 0.0626897 28.883102 0.0000000 0.0000000 ENSG00000136826.15 A0A087X0S4 KLF4 KLF4 9314 KLF transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:6348] protein_coding
ENSG00000140297 1379.857252 1.937202 0.0673472 28.764376 0.0000000 0.0000000 ENSG00000140297.13 A0A024R5T9 GCNT3 GCNT3 9245 glucosaminyl (N-acetyl) transferase 3, mucin type [Source:HGNC Symbol;Acc:HGNC:4205] protein_coding
ENSG00000109861 7403.125064 1.876175 0.0658900 28.474343 0.0000000 0.0000000 ENSG00000109861.17 A0A7I2V3A6 CTSC CTSC 1075 cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] protein_coding
ENSG00000117143 2642.687344 1.919200 0.0709155 27.063199 0.0000000 0.0000000 ENSG00000117143.14 Q16222 UAP1 UAP1 6675 UDP-N-acetylglucosamine pyrophosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12457] protein_coding
ENSG00000189221 3303.326476 2.181542 0.0827669 26.357655 0.0000000 0.0000000 ENSG00000189221.11 P21397 MAOA MAOA 4128 monoamine oxidase A [Source:HGNC Symbol;Acc:HGNC:6833] protein_coding
ENSG00000164309 882.869631 2.856101 0.1097296 26.028542 0.0000000 0.0000000 ENSG00000164309.15 Q8N3K9 CMYA5 CMYA5 202333 cardiomyopathy associated 5 [Source:HGNC Symbol;Acc:HGNC:14305] protein_coding
ENSG00000287059 565.582046 6.999321 0.2762242 25.339275 0.0000000 0.0000000 ENSG00000287059.1 NA novel transcript lncRNA
ENSG00000198574 593.987947 6.629282 0.2617975 25.322176 0.0000000 0.0000000 ENSG00000198574.6 O14796 SH2D1B SH2D1B 117157 SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416] protein_coding
ENSG00000153822 420.909653 3.300089 0.1309082 25.209192 0.0000000 0.0000000 ENSG00000153822.15 Q9NPI9 KCNJ16 KCNJ16 3773 potassium inwardly rectifying channel subfamily J member 16 [Source:HGNC Symbol;Acc:HGNC:6262] protein_coding
ENSG00000165449 1094.288492 2.203801 0.0893697 24.659391 0.0000000 0.0000000 ENSG00000165449.12 Q7RTY1 SLC16A9 SLC16A9 220963 solute carrier family 16 member 9 [Source:HGNC Symbol;Acc:HGNC:23520] protein_coding
ENSG00000164038 412.905503 2.985782 0.1227473 24.324633 0.0000000 0.0000000 ENSG00000164038.16 Q86UD5 SLC9B2 SLC9B2 133308 solute carrier family 9 member B2 [Source:HGNC Symbol;Acc:HGNC:25143] protein_coding
ENSG00000048028 1123.127543 1.763157 0.0736177 23.950187 0.0000000 0.0000000 ENSG00000048028.12 G3V1N5 USP28 USP28 57646 ubiquitin specific peptidase 28 [Source:HGNC Symbol;Acc:HGNC:12625] protein_coding
ENSG00000167600 2633.518094 1.620056 0.0678329 23.883030 0.0000000 0.0000000 ENSG00000167600.14 M0R057 CYP2S1 CYP2S1 29785 cytochrome P450 family 2 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:15654] protein_coding
ENSG00000186832 917.455341 2.256355 0.0955480 23.614881 0.0000000 0.0000000 ENSG00000186832.9 P08779 KRT16 KRT16 3868 keratin 16 [Source:HGNC Symbol;Acc:HGNC:6423] protein_coding
ENSG00000140105 6108.437520 1.784429 0.0796616 22.400112 0.0000000 0.0000000 ENSG00000140105.18 G3V423 WARS1 WARS1 7453 tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] protein_coding
ENSG00000197641 2089.207801 1.587012 0.0709591 22.365142 0.0000000 0.0000000 ENSG00000197641.12 Q9UIV8 SERPINB13 SERPINB13 5275 serpin family B member 13 [Source:HGNC Symbol;Acc:HGNC:8944] protein_coding
ENSG00000128268 666.044381 2.271025 0.1044752 21.737444 0.0000000 0.0000000 ENSG00000128268.12 Q09327 MGAT3 MGAT3 4248 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7046] protein_coding
ENSG00000111817 1598.693848 1.192228 0.0551818 21.605470 0.0000000 0.0000000 ENSG00000111817.19 A0A2R8YE23 DSE DSE 29940 dermatan sulfate epimerase [Source:HGNC Symbol;Acc:HGNC:21144] protein_coding
ENSG00000168389 1042.618103 1.588478 0.0735845 21.587137 0.0000000 0.0000000 ENSG00000168389.18 E7EPI8 MFSD2A MFSD2A 84879 MFSD2 lysolipid transporter A, lysophospholipid [Source:HGNC Symbol;Acc:HGNC:25897] protein_coding
ENSG00000170961 333.073004 3.955609 0.1855379 21.319675 0.0000000 0.0000000 ENSG00000170961.7 Q92819 HAS2 HAS2 3037 hyaluronan synthase 2 [Source:HGNC Symbol;Acc:HGNC:4819] protein_coding
ENSG00000120217 336.492845 3.124909 0.1475468 21.179109 0.0000000 0.0000000 ENSG00000120217.14 Q9NZQ7 CD274 CD274 29126 CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635] protein_coding
ENSG00000196611 1161.479019 2.209837 0.1048096 21.084298 0.0000000 0.0000000 ENSG00000196611.6 P03956 MMP1 MMP1 4312 matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] protein_coding
ENSG00000103942 1086.835530 1.600973 0.0762009 21.009893 0.0000000 0.0000000 ENSG00000103942.13 H0YNR9 HOMER2 HOMER2 9455 homer scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:17513] protein_coding
ENSG00000248144 2144.760151 1.865280 0.0902403 20.670139 0.0000000 0.0000000 ENSG00000248144.6 P00326 ADH1C ADH1C 126 alcohol dehydrogenase 1C (class I), gamma polypeptide [Source:HGNC Symbol;Acc:HGNC:251] protein_coding
ENSG00000002587 1634.071113 1.903113 0.0921024 20.663020 0.0000000 0.0000000 ENSG00000002587.10 O14792 HS3ST1 HS3ST1 9957 heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] protein_coding
ENSG00000170745 435.427653 2.417877 0.1201534 20.123251 0.0000000 0.0000000 ENSG00000170745.12 Q9BQ31 KCNS3 KCNS3 3790 potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] protein_coding
ENSG00000012660 4940.983963 1.294956 0.0646660 20.025299 0.0000000 0.0000000 ENSG00000012660.14 Q9NYP7 ELOVL5 ELOVL5 60481 ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] protein_coding
ENSG00000138821 432.396839 2.400801 0.1205463 19.916018 0.0000000 0.0000000 ENSG00000138821.14 Q9C0K1 SLC39A8 SLC39A8 64116 solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] protein_coding
ENSG00000268104 5939.325411 1.186990 0.0596070 19.913596 0.0000000 0.0000000 ENSG00000268104.3 Q9UN76 SLC6A14 SLC6A14 11254 solute carrier family 6 member 14 [Source:HGNC Symbol;Acc:HGNC:11047] protein_coding
ENSG00000075673 4771.572999 2.985658 0.1539577 19.392714 0.0000000 0.0000000 ENSG00000075673.12 P54707 ATP12A ATP12A 479 ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] protein_coding
ENSG00000131711 5640.934424 1.488555 0.0777020 19.157231 0.0000000 0.0000000 ENSG00000131711.15 P46821 MAP1B MAP1B 4131 microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] protein_coding
ENSG00000175538 456.921044 1.951605 0.1019827 19.136635 0.0000000 0.0000000 ENSG00000175538.11 Q9Y6H6 KCNE3 KCNE3 10008 potassium voltage-gated channel subfamily E regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:6243] protein_coding
ENSG00000099994 229.080408 4.549196 0.2379301 19.119887 0.0000000 0.0000000 ENSG00000099994.11 A0A140VJW3 SUSD2 SUSD2 56241 sushi domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30667] protein_coding
ENSG00000213626 1198.174106 1.311557 0.0693512 18.911809 0.0000000 0.0000000 ENSG00000213626.13 B5MCM2 LBH LBH 81606 LBH regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:29532] protein_coding
ENSG00000185338 183.695251 4.218318 0.2232076 18.898626 0.0000000 0.0000000 ENSG00000185338.7 O15524 SOCS1 SOCS1 8651 suppressor of cytokine signaling 1 [Source:HGNC Symbol;Acc:HGNC:19383] protein_coding
ENSG00000114737 262.742501 6.365583 0.3374397 18.864358 0.0000000 0.0000000 ENSG00000114737.16 Q9NSE2 CISH CISH 1154 cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] protein_coding
ENSG00000197635 186.506933 4.449111 0.2376940 18.717812 0.0000000 0.0000000 ENSG00000197635.11 A0A7I2V2I2 DPP4 DPP4 1803 dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] protein_coding
ENSG00000110799 167.758806 4.413766 0.2358061 18.717779 0.0000000 0.0000000 ENSG00000110799.14 P04275 VWF VWF 7450 von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726] protein_coding
ENSG00000261150 5158.608355 1.186126 0.0634917 18.681589 0.0000000 0.0000000 ENSG00000261150.3 P58107 EPPK1 EPPK1 83481 epiplakin 1 [Source:HGNC Symbol;Acc:HGNC:15577] protein_coding
ENSG00000104267 216.876412 4.114160 0.2202422 18.680162 0.0000000 0.0000000 ENSG00000104267.10 E5RK37 CA2 CA2 760 carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] protein_coding
ENSG00000074054 2438.868307 1.191130 0.0641941 18.555126 0.0000000 0.0000000 ENSG00000074054.21 C9J151 CLASP1 CLASP1 23332 cytoplasmic linker associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17088] protein_coding
ENSG00000156463 1128.091026 1.467289 0.0791891 18.528921 0.0000000 0.0000000 ENSG00000156463.18 Q8TEC5 SH3RF2 SH3RF2 153769 SH3 domain containing ring finger 2 [Source:HGNC Symbol;Acc:HGNC:26299] protein_coding
ENSG00000196167 1543.257977 1.363873 0.0739645 18.439555 0.0000000 0.0000000 ENSG00000196167.10 COLCA1 399948 colorectal cancer associated 1 [Source:HGNC Symbol;Acc:HGNC:33789] lncRNA
ENSG00000110090 1397.272635 1.166661 0.0633149 18.426329 0.0000000 0.0000000 ENSG00000110090.13 H3BUJ0 CPT1A CPT1A 1374 carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] protein_coding
ENSG00000155846 710.759377 1.628032 0.0884125 18.414057 0.0000000 0.0000000 ENSG00000155846.17 Q86YN6 PPARGC1B PPARGC1B 133522 PPARG coactivator 1 beta [Source:HGNC Symbol;Acc:HGNC:30022] protein_coding
ENSG00000135069 1207.885673 1.699441 0.0925032 18.371692 0.0000000 0.0000000 ENSG00000135069.14 Q9Y617 PSAT1 PSAT1 29968 phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:19129] protein_coding
ENSG00000151327 942.992140 1.371369 0.0751065 18.258990 0.0000000 0.0000000 ENSG00000151327.14 H0YJC3 FAM177A1 FAM177A1 283635 family with sequence similarity 177 member A1 [Source:HGNC Symbol;Acc:HGNC:19829] protein_coding
ENSG00000148175 12068.978780 1.176626 0.0644702 18.250677 0.0000000 0.0000000 ENSG00000148175.13 P27105 STOM STOM 2040 stomatin [Source:HGNC Symbol;Acc:HGNC:3383] protein_coding
ENSG00000181449 2602.889459 1.055677 0.0582851 18.112278 0.0000000 0.0000000 ENSG00000181449.4 P48431 SOX2 SOX2 6657 SRY-box transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11195] protein_coding
ENSG00000103044 1493.467970 1.686501 0.0934638 18.044428 0.0000000 0.0000000 ENSG00000103044.11 H3BRH5 HAS3 HAS3 3038 hyaluronan synthase 3 [Source:HGNC Symbol;Acc:HGNC:4820] protein_coding
ENSG00000171492 860.882249 1.606234 0.0904865 17.751093 0.0000000 0.0000000 ENSG00000171492.14 E9PMF9 LRRC8D LRRC8D 55144 leucine rich repeat containing 8 VRAC subunit D [Source:HGNC Symbol;Acc:HGNC:16992] protein_coding
ENSG00000064651 2849.855806 1.038105 0.0586697 17.694060 0.0000000 0.0000000 ENSG00000064651.14 P55011 SLC12A2 SLC12A2 6558 solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] protein_coding
ENSG00000173559 669.534552 2.022326 0.1165740 17.347999 0.0000000 0.0000000 ENSG00000173559.15 Q96AH0 NABP1 NABP1 64859 nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232] protein_coding
ENSG00000140022 4085.842729 1.054403 0.0610954 17.258304 0.0000000 0.0000000 ENSG00000140022.14 H0YJ05 STON2 STON2 85439 stonin 2 [Source:HGNC Symbol;Acc:HGNC:30652] protein_coding
ENSG00000268628 289.871111 2.585453 0.1511206 17.108535 0.0000000 0.0000000 ENSG00000268628.2 NA novel transcript lncRNA
ENSG00000233705 286.715205 2.752796 0.1611786 17.079159 0.0000000 0.0000000 ENSG00000233705.9 SLC26A4-AS1 NA SLC26A4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:22385] lncRNA
ENSG00000073849 5043.999591 1.131669 0.0663829 17.047608 0.0000000 0.0000000 ENSG00000073849.16 C9K0R8 ST6GAL1 ST6GAL1 6480 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10860] protein_coding
ENSG00000106537 1437.139117 1.227505 0.0725082 16.929184 0.0000000 0.0000000 ENSG00000106537.8 O95857 TSPAN13 TSPAN13 27075 tetraspanin 13 [Source:HGNC Symbol;Acc:HGNC:21643] protein_coding
ENSG00000126016 1177.685773 1.251090 0.0751502 16.647847 0.0000000 0.0000000 ENSG00000126016.17 E7ERM3 AMOT AMOT 154796 angiomotin [Source:HGNC Symbol;Acc:HGNC:17810] protein_coding
ENSG00000139304 492.376357 1.674906 0.1006541 16.640213 0.0000000 0.0000000 ENSG00000139304.16 A0A087WZU1 PTPRQ PTPRQ 374462 protein tyrosine phosphatase receptor type Q [Source:HGNC Symbol;Acc:HGNC:9679] protein_coding
ENSG00000186480 3171.726178 1.002283 0.0604091 16.591590 0.0000000 0.0000000 ENSG00000186480.13 C9JSG8 INSIG1 INSIG1 3638 insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] protein_coding
ENSG00000101445 493.884479 1.663694 0.1013895 16.408931 0.0000000 0.0000000 ENSG00000101445.10 Q96T49 PPP1R16B PPP1R16B 26051 protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] protein_coding
ENSG00000128274 1550.139220 1.010458 0.0619577 16.308843 0.0000000 0.0000000 ENSG00000128274.17 Q9NPC4 A4GALT A4GALT 53947 alpha 1,4-galactosyltransferase (P blood group) [Source:HGNC Symbol;Acc:HGNC:18149] protein_coding
ENSG00000121207 449.607612 1.667906 0.1028757 16.212820 0.0000000 0.0000000 ENSG00000121207.12 O95237 LRAT LRAT 9227 lecithin retinol acyltransferase [Source:HGNC Symbol;Acc:HGNC:6685] protein_coding
ENSG00000081026 1203.137306 1.049371 0.0650457 16.132840 0.0000000 0.0000000 ENSG00000081026.19 Q5TCQ9 MAGI3 MAGI3 260425 membrane associated guanylate kinase, WW and PDZ domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29647] protein_coding
ENSG00000150551 142.609152 3.405285 0.2111612 16.126465 0.0000000 0.0000000 ENSG00000150551.11 Q8N2G4 LYPD1 LYPD1 116372 LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] protein_coding
ENSG00000137563 646.817608 1.701212 0.1061262 16.030090 0.0000000 0.0000000 ENSG00000137563.13 Q92820 GGH GGH 8836 gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] protein_coding
ENSG00000165071 247.974337 2.456505 0.1539093 15.960735 0.0000000 0.0000000 ENSG00000165071.15 E5RGD3 TMEM71 TMEM71 137835 transmembrane protein 71 [Source:HGNC Symbol;Acc:HGNC:26572] protein_coding
ENSG00000174514 881.582570 1.121027 0.0705721 15.884834 0.0000000 0.0000000 ENSG00000174514.13 A0A087WYZ8 MFSD4A MFSD4A 148808 major facilitator superfamily domain containing 4A [Source:HGNC Symbol;Acc:HGNC:25433] protein_coding
ENSG00000188641 1464.970642 1.279681 0.0807930 15.839012 0.0000000 0.0000000 ENSG00000188641.14 Q12882 DPYD DPYD 1806 dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012] protein_coding
ENSG00000169439 163.599715 2.841579 0.1817964 15.630559 0.0000000 0.0000000 ENSG00000169439.12 E9PBI9 SDC2 SDC2 6383 syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] protein_coding
ENSG00000139668 827.771163 1.098478 0.0703585 15.612586 0.0000000 0.0000000 ENSG00000139668.9 A0A087WZX3 WDFY2 WDFY2 115825 WD repeat and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20482] protein_coding
ENSG00000173918 135.365666 3.783216 0.2437202 15.522786 0.0000000 0.0000000 ENSG00000173918.15 Q9BXJ1 C1QTNF1 C1QTNF1 114897 C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] protein_coding
ENSG00000140479 149.585352 2.671804 0.1724192 15.495973 0.0000000 0.0000000 ENSG00000140479.18 A0A7I2YQH5 PCSK6 PCSK6 5046 proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569] protein_coding
ENSG00000082497 749.124502 1.455596 0.0939828 15.487897 0.0000000 0.0000000 ENSG00000082497.12 Q9NUC0 SERTAD4 SERTAD4 56256 SERTA domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25236] protein_coding
ENSG00000106105 1584.352773 1.201075 0.0775522 15.487312 0.0000000 0.0000000 ENSG00000106105.15 A0A6Q8PH49 GARS1 GARS1 2617 glycyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:4162] protein_coding
ENSG00000135218 232.060484 2.513503 0.1641693 15.310434 0.0000000 0.0000000 ENSG00000135218.19 E7EU05 CD36 CD36 948 CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663] protein_coding
ENSG00000265451 123.156143 4.392048 0.2871014 15.297897 0.0000000 0.0000000 ENSG00000265451.1 CLASP1-AS1 NA CLASP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:55328] lncRNA
ENSG00000120314 629.620662 1.274968 0.0833664 15.293556 0.0000000 0.0000000 ENSG00000120314.19 Q9H6Y2 WDR55 WDR55 54853 WD repeat domain 55 [Source:HGNC Symbol;Acc:HGNC:25971] protein_coding
ENSG00000224259 324.190925 1.679880 0.1121129 14.983818 0.0000000 0.0000000 ENSG00000224259.9 LINC01133 NA long intergenic non-protein coding RNA 1133 [Source:HGNC Symbol;Acc:HGNC:49447] lncRNA
ENSG00000160285 2227.956667 1.193935 0.0798827 14.946116 0.0000000 0.0000000 ENSG00000160285.15 P48449 LSS LSS 4047 lanosterol synthase [Source:HGNC Symbol;Acc:HGNC:6708] protein_coding
ENSG00000140254 896.901114 1.221837 0.0820215 14.896549 0.0000000 0.0000000 ENSG00000140254.13 H0YNR1 DUOXA1 DUOXA1 90527 dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] protein_coding
ENSG00000122591 655.092440 1.340989 0.0900456 14.892337 0.0000000 0.0000000 ENSG00000122591.13 A0A7P0Z4L0 HYCC1 HYCC1 84668 hyccin PI4KA lipid kinase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24587] protein_coding
ENSG00000139324 6039.770798 1.128329 0.0761250 14.822053 0.0000000 0.0000000 ENSG00000139324.12 F8VRY4 TMTC3 TMTC3 160418 transmembrane O-mannosyltransferase targeting cadherins 3 [Source:HGNC Symbol;Acc:HGNC:26899] protein_coding
ENSG00000178033 145.147927 3.366514 0.2275548 14.794299 0.0000000 0.0000000 ENSG00000178033.6 Q8N5C1 CALHM5 CALHM5 254228 calcium homeostasis modulator family member 5 [Source:HGNC Symbol;Acc:HGNC:21568] protein_coding
ENSG00000124664 180.237854 2.590554 0.1759735 14.721278 0.0000000 0.0000000 ENSG00000124664.11 O95238 SPDEF SPDEF 25803 SAM pointed domain containing ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:17257] protein_coding
ENSG00000057657 534.570659 1.533678 0.1051470 14.586042 0.0000000 0.0000000 ENSG00000057657.17 B2REA5 PRDM1 PRDM1 639 PR/SET domain 1 [Source:HGNC Symbol;Acc:HGNC:9346] protein_coding
ENSG00000107959 1726.108926 1.084629 0.0745479 14.549426 0.0000000 0.0000000 ENSG00000107959.17 A0A7I2V3B6 PITRM1 PITRM1 10531 pitrilysin metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:17663] protein_coding
ENSG00000006606 2183.335634 12.052154 0.8366223 14.405730 0.0000000 0.0000000 ENSG00000006606.9 Q9Y258 CCL26 CCL26 10344 C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625] protein_coding
ENSG00000169860 463.598747 1.400648 0.0974151 14.378144 0.0000000 0.0000000 ENSG00000169860.7 P47900 P2RY1 P2RY1 5028 purinergic receptor P2Y1 [Source:HGNC Symbol;Acc:HGNC:8539] protein_coding
ENSG00000186854 97.560545 3.377891 0.2362317 14.299060 0.0000000 0.0000000 ENSG00000186854.11 Q86V40 TRABD2A TRABD2A 105374836 TraB domain containing 2A [Source:HGNC Symbol;Acc:HGNC:27013] protein_coding
ENSG00000050327 429.745430 1.450470 0.1015098 14.288965 0.0000000 0.0000000 ENSG00000050327.15 Q12774 ARHGEF5 ARHGEF5 7984 Rho guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:13209] protein_coding
ENSG00000165474 2851.437944 1.405180 0.0987934 14.223416 0.0000000 0.0000000 ENSG00000165474.8 P29033 GJB2 GJB2 2706 gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] protein_coding
ENSG00000072786 552.126075 1.307090 0.0925086 14.129385 0.0000000 0.0000000 ENSG00000072786.13 O94804 STK10 STK10 6793 serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] protein_coding
ENSG00000026508 9801.201960 1.854421 0.1314286 14.109721 0.0000000 0.0000000 ENSG00000026508.21 H0YCV9 CD44 CD44 960 CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] protein_coding
ENSG00000090512 204.676322 7.819485 0.5610818 13.936445 0.0000000 0.0000000 ENSG00000090512.12 Q9UGM5 FETUB FETUB 26998 fetuin B [Source:HGNC Symbol;Acc:HGNC:3658] protein_coding
ENSG00000065911 1001.183076 1.301874 0.0942720 13.809761 0.0000000 0.0000000 ENSG00000065911.13 A0A7I2V3T1 MTHFD2 MTHFD2 10797 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] protein_coding
ENSG00000125945 636.967348 1.126901 0.0820659 13.731651 0.0000000 0.0000000 ENSG00000125945.16 Q9C0F3 ZNF436 ZNF436 80818 zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814] protein_coding
ENSG00000138135 244.719427 2.200854 0.1610678 13.664147 0.0000000 0.0000000 ENSG00000138135.7 O95992 CH25H CH25H 9023 cholesterol 25-hydroxylase [Source:HGNC Symbol;Acc:HGNC:1907] protein_coding
ENSG00000041982 3444.001025 1.245392 0.0922211 13.504414 0.0000000 0.0000000 ENSG00000041982.17 A0A0U1RR80 TNC TNC 3371 tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] protein_coding
ENSG00000022567 1129.926683 1.055550 0.0786247 13.425168 0.0000000 0.0000000 ENSG00000022567.10 E7EV90 SLC45A4 SLC45A4 57210 solute carrier family 45 member 4 [Source:HGNC Symbol;Acc:HGNC:29196] protein_coding
ENSG00000227243 96.119598 4.507588 0.3362615 13.405010 0.0000000 0.0000000 ENSG00000227243.3 SLAMF6P1 NA SLAM family member 6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32012] unprocessed_pseudogene
ENSG00000261040 1672.298952 1.103279 0.0826452 13.349582 0.0000000 0.0000000 ENSG00000261040.10 WFDC21P NA WAP four-disulfide core domain 21, pseudogene [Source:HGNC Symbol;Acc:HGNC:50357] transcribed_unitary_pseudogene
ENSG00000136869 234.212978 2.209044 0.1656336 13.336935 0.0000000 0.0000000 ENSG00000136869.16 O00206 TLR4 TLR4 7099 toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] protein_coding
ENSG00000114248 174.549137 7.064789 0.5303494 13.321007 0.0000000 0.0000000 ENSG00000114248.10 Q6UY01 LRRC31 LRRC31 79782 leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] protein_coding
ENSG00000107960 615.197458 1.081768 0.0818387 13.218303 0.0000000 0.0000000 ENSG00000107960.12 A0A8V8TN12 STN1 STN1 79991 STN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:26200] protein_coding
ENSG00000134824 2545.745645 1.050735 0.0800924 13.119033 0.0000000 0.0000000 ENSG00000134824.14 O95864 FADS2 FADS2 9415 fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] protein_coding
ENSG00000120756 6233.533474 1.104151 0.0843352 13.092417 0.0000000 0.0000000 ENSG00000120756.13 C9JYI1 PLS1 PLS1 5357 plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090] protein_coding
ENSG00000163931 2190.969241 1.020133 0.0779256 13.091109 0.0000000 0.0000000 ENSG00000163931.17 V9HWD9 HEL107 TKT 7086 transketolase [Source:HGNC Symbol;Acc:HGNC:11834] protein_coding
ENSG00000127528 141.467140 2.549616 0.1959871 13.009103 0.0000000 0.0000000 ENSG00000127528.6 Q9Y5W3 KLF2 KLF2 10365 KLF transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:6347] protein_coding
ENSG00000167508 1108.457351 1.191758 0.0916779 12.999406 0.0000000 0.0000000 ENSG00000167508.12 H3BVC4 MVD MVD 4597 mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529] protein_coding
ENSG00000144824 836.207977 1.308791 0.1009921 12.959337 0.0000000 0.0000000 ENSG00000144824.21 A0A1W2PRT1 PHLDB2 PHLDB2 90102 pleckstrin homology like domain family B member 2 [Source:HGNC Symbol;Acc:HGNC:29573] protein_coding
ENSG00000100170 273.414767 2.120807 0.1651718 12.840010 0.0000000 0.0000000 ENSG00000100170.10 P13866 SLC5A1 SLC5A1 6523 solute carrier family 5 member 1 [Source:HGNC Symbol;Acc:HGNC:11036] protein_coding
ENSG00000132205 113.001347 3.890763 0.3032643 12.829612 0.0000000 0.0000000 ENSG00000132205.11 Q9BXX0 EMILIN2 EMILIN2 84034 elastin microfibril interfacer 2 [Source:HGNC Symbol;Acc:HGNC:19881] protein_coding
ENSG00000114771 79.230086 4.052483 0.3173465 12.769900 0.0000000 0.0000000 ENSG00000114771.14 P22760 AADAC AADAC 13 arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] protein_coding
ENSG00000125037 1078.493987 1.040996 0.0824864 12.620217 0.0000000 0.0000000 ENSG00000125037.13 A0A8I5KS41 EMC3 EMC3 55831 ER membrane protein complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:23999] protein_coding
ENSG00000238837 119.046269 2.210155 0.1756369 12.583655 0.0000000 0.0000000 ENSG00000238837.3 LINC02031 NA long intergenic non-protein coding RNA 2031 [Source:HGNC Symbol;Acc:HGNC:52865] lncRNA
ENSG00000141480 294.259336 1.368903 0.1110189 12.330355 0.0000000 0.0000000 ENSG00000141480.18 P32121 ARRB2 ARRB2 409 arrestin beta 2 [Source:HGNC Symbol;Acc:HGNC:712] protein_coding
ENSG00000179914 79.467140 3.176468 0.2579623 12.313688 0.0000000 0.0000000 ENSG00000179914.5 Q8WWA0 ITLN1 ITLN1 55600 intelectin 1 [Source:HGNC Symbol;Acc:HGNC:18259] protein_coding
ENSG00000101298 166.206429 2.692191 0.2192411 12.279593 0.0000000 0.0000000 ENSG00000101298.15 O15079 SNPH SNPH 9751 syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] protein_coding
ENSG00000155918 126.183936 2.755353 0.2256637 12.209997 0.0000000 0.0000000 ENSG00000155918.8 Q5VY80 RAET1L RAET1L 154064 retinoic acid early transcript 1L [Source:HGNC Symbol;Acc:HGNC:16798] protein_coding
ENSG00000169926 1074.553090 1.105169 0.0910055 12.143976 0.0000000 0.0000000 ENSG00000169926.11 Q9Y2Y9 KLF13 KLF13 51621 KLF transcription factor 13 [Source:HGNC Symbol;Acc:HGNC:13672] protein_coding
ENSG00000166986 1413.713955 1.051615 0.0870652 12.078479 0.0000000 0.0000000 ENSG00000166986.15 F8W0S4 MARS1 MARS1 4141 methionyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6898] protein_coding
ENSG00000122335 592.249993 1.143089 0.0948079 12.056893 0.0000000 0.0000000 ENSG00000122335.17 A0A2R8Y3S0 SERAC1 SERAC1 84947 serine active site containing 1 [Source:HGNC Symbol;Acc:HGNC:21061] protein_coding
ENSG00000131069 1133.252872 1.003196 0.0833411 12.037228 0.0000000 0.0000000 ENSG00000131069.20 F8WC73 ACSS2 ACSS2 55902 acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814] protein_coding
ENSG00000196352 1254.146381 1.075394 0.0899683 11.953034 0.0000000 0.0000000 ENSG00000196352.18 B1AP13 CD55 CD55 1604 CD55 molecule (Cromer blood group) [Source:HGNC Symbol;Acc:HGNC:2665] protein_coding
ENSG00000244694 376.354273 1.309919 0.1097096 11.939872 0.0000000 0.0000000 ENSG00000244694.8 A0A7P0TAD5 PTCHD4 PTCHD4 442213 patched domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21345] protein_coding
ENSG00000121552 1558.370175 1.317873 0.1112468 11.846389 0.0000000 0.0000000 ENSG00000121552.4 P01040 CSTA CSTA 1475 cystatin A [Source:HGNC Symbol;Acc:HGNC:2481] protein_coding
ENSG00000164574 440.681900 1.330961 0.1126553 11.814456 0.0000000 0.0000000 ENSG00000164574.16 F2Z2M7 GALNT10 GALNT10 55568 polypeptide N-acetylgalactosaminyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19873] protein_coding
ENSG00000213214 186.216588 1.683973 0.1428547 11.788018 0.0000000 0.0000000 ENSG00000213214.6 A5YM69 ARHGEF35 ARHGEF35 445328 Rho guanine nucleotide exchange factor 35 [Source:HGNC Symbol;Acc:HGNC:33846] protein_coding
ENSG00000116299 621.791557 1.156020 0.0986510 11.718279 0.0000000 0.0000000 ENSG00000116299.17 E9PLQ2 ELAPOR1 ELAPOR1 57535 endosome-lysosome associated apoptosis and autophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:29618] protein_coding
ENSG00000120053 464.454310 1.056549 0.0903054 11.699733 0.0000000 0.0000000 ENSG00000120053.12 P17174 GOT1 GOT1 2805 glutamic-oxaloacetic transaminase 1 [Source:HGNC Symbol;Acc:HGNC:4432] protein_coding
ENSG00000157240 379.760919 1.122847 0.0970258 11.572668 0.0000000 0.0000000 ENSG00000157240.4 Q9UP38 FZD1 FZD1 8321 frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038] protein_coding
ENSG00000078725 137.724911 2.084306 0.1859553 11.208639 0.0000000 0.0000000 ENSG00000078725.13 O60477 BRINP1 BRINP1 1620 BMP/retinoic acid inducible neural specific 1 [Source:HGNC Symbol;Acc:HGNC:2687] protein_coding
ENSG00000198759 377.786958 1.561551 0.1395947 11.186319 0.0000000 0.0000000 ENSG00000198759.12 Q8IUX8 EGFL6 EGFL6 25975 EGF like domain multiple 6 [Source:HGNC Symbol;Acc:HGNC:3235] protein_coding
ENSG00000147697 276.936595 1.362129 0.1218625 11.177588 0.0000000 0.0000000 ENSG00000147697.10 A0A2R8Y5J4 GSDMC GSDMC 56169 gasdermin C [Source:HGNC Symbol;Acc:HGNC:7151] protein_coding
ENSG00000133110 73.579917 3.135255 0.2809999 11.157492 0.0000000 0.0000000 ENSG00000133110.15 A0A024RDS2 POSTN POSTN 10631 periostin [Source:HGNC Symbol;Acc:HGNC:16953] protein_coding
ENSG00000088280 325.076135 1.139777 0.1039455 10.965145 0.0000000 0.0000000 ENSG00000088280.21 V9GY49 ASAP3 ASAP3 55616 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:14987] protein_coding
ENSG00000198488 100.618529 2.626603 0.2410260 10.897593 0.0000000 0.0000000 ENSG00000198488.10 Q6ZMB0 B3GNT6 B3GNT6 192134 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:24141] protein_coding
ENSG00000091137 2888.864863 3.231816 0.3033271 10.654559 0.0000000 0.0000000 ENSG00000091137.14 O43511 SLC26A4 SLC26A4 5172 solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] protein_coding
ENSG00000174175 96.936094 2.981848 0.2826885 10.548176 0.0000000 0.0000000 ENSG00000174175.17 Q5R345 SELP SELP 6403 selectin P [Source:HGNC Symbol;Acc:HGNC:10721] protein_coding
ENSG00000119121 65.230056 3.526909 0.3353960 10.515655 0.0000000 0.0000000 ENSG00000119121.22 Q9BX84 TRPM6 TRPM6 140803 transient receptor potential cation channel subfamily M member 6 [Source:HGNC Symbol;Acc:HGNC:17995] protein_coding
ENSG00000108448 276.867865 1.204944 0.1156160 10.421944 0.0000000 0.0000000 ENSG00000108448.24 TRIM16L NA tripartite motif containing 16 like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:32670] transcribed_unprocessed_pseudogene
ENSG00000118729 43.852720 4.086536 0.3937584 10.378282 0.0000000 0.0000000 ENSG00000118729.13 O14958 CASQ2 CASQ2 845 calsequestrin 2 [Source:HGNC Symbol;Acc:HGNC:1513] protein_coding
ENSG00000142224 87.996501 4.425735 0.4288447 10.320136 0.0000000 0.0000000 ENSG00000142224.18 Q9UHD0 IL19 IL19 29949 interleukin 19 [Source:HGNC Symbol;Acc:HGNC:5990] protein_coding
ENSG00000151617 70.897733 3.138963 0.3041557 10.320249 0.0000000 0.0000000 ENSG00000151617.17 P25101 EDNRA EDNRA 1909 endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] protein_coding
ENSG00000182389 92.234641 2.271477 0.2234801 10.164113 0.0000000 0.0000000 ENSG00000182389.20 H0Y476 CACNB4 CACNB4 785 calcium voltage-gated channel auxiliary subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:1404] protein_coding
ENSG00000103089 226.833282 1.379639 0.1361414 10.133866 0.0000000 0.0000000 ENSG00000103089.9 H3BP32 FA2H FA2H 79152 fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] protein_coding
ENSG00000114738 388.796686 1.113741 0.1100445 10.120821 0.0000000 0.0000000 ENSG00000114738.11 A0A024R2W7 MAPKAPK3 MAPKAPK3 7867 MAPK activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6888] protein_coding
ENSG00000066230 70.197131 3.043212 0.3032079 10.036717 0.0000000 0.0000000 ENSG00000066230.12 P48764 SLC9A3 SLC9A3 6550 solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] protein_coding
ENSG00000127152 168.800722 1.722161 0.1717757 10.025637 0.0000000 0.0000000 ENSG00000127152.18 D3YTK1 BCL11B BCL11B 64919 BCL11 transcription factor B [Source:HGNC Symbol;Acc:HGNC:13222] protein_coding
ENSG00000275395 2083.389464 1.525074 0.1524470 10.003963 0.0000000 0.0000000 ENSG00000275395.7 A0A087WXI2 FCGBP FCGBP 8857 Fc gamma binding protein [Source:HGNC Symbol;Acc:HGNC:13572] protein_coding
ENSG00000145934 1727.042073 1.108342 0.1112779 9.960132 0.0000000 0.0000000 ENSG00000145934.17 F8VNQ3 TENM2 TENM2 57451 teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] protein_coding
ENSG00000114993 300.049168 1.175075 0.1188681 9.885541 0.0000000 0.0000000 ENSG00000114993.17 Q9BST9 RTKN RTKN 6242 rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] protein_coding
ENSG00000125775 352.587729 1.262353 0.1281959 9.847062 0.0000000 0.0000000 ENSG00000125775.15 Q9H190 SDCBP2 SDCBP2 27111 syndecan binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15756] protein_coding
ENSG00000126549 87.571345 2.361085 0.2401878 9.830160 0.0000000 0.0000000 ENSG00000126549.11 P02808 STATH STATH 6779 statherin [Source:HGNC Symbol;Acc:HGNC:11369] protein_coding
ENSG00000203722 218.489428 1.327733 0.1353104 9.812496 0.0000000 0.0000000 ENSG00000203722.8 Q6H3X3 RAET1G RAET1G 353091 retinoic acid early transcript 1G [Source:HGNC Symbol;Acc:HGNC:16795] protein_coding
ENSG00000163993 811.690361 1.073685 0.1104414 9.721766 0.0000000 0.0000000 ENSG00000163993.7 P25815 S100P S100P 6286 S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] protein_coding
ENSG00000101255 212.168911 1.472266 0.1514784 9.719315 0.0000000 0.0000000 ENSG00000101255.12 J3KR25 TRIB3 TRIB3 57761 tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228] protein_coding
ENSG00000167617 135.393864 1.706851 0.1756530 9.717177 0.0000000 0.0000000 ENSG00000167617.3 Q6NZY7 CDC42EP5 CDC42EP5 148170 CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408] protein_coding
ENSG00000197646 70.465740 2.424478 0.2506465 9.672900 0.0000000 0.0000000 ENSG00000197646.8 Q9BQ51 PDCD1LG2 PDCD1LG2 80380 programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] protein_coding
ENSG00000242265 333.737479 1.564567 0.1617669 9.671734 0.0000000 0.0000000 ENSG00000242265.6 A0A087WX23 PEG10 PEG10 23089 paternally expressed 10 [Source:HGNC Symbol;Acc:HGNC:14005] protein_coding
ENSG00000103888 455.011361 2.160342 0.2236899 9.657756 0.0000000 0.0000000 ENSG00000103888.17 Q8WUJ3 CEMIP CEMIP 57214 cell migration inducing hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:29213] protein_coding
ENSG00000267107 52.508308 2.735829 0.2846214 9.612170 0.0000000 0.0000000 ENSG00000267107.9 PCAT19 100505495 prostate cancer associated transcript 19 [Source:HGNC Symbol;Acc:HGNC:49593] lncRNA
ENSG00000179023 270.930919 1.128968 0.1176932 9.592467 0.0000000 0.0000000 ENSG00000179023.9 Q5VTJ3 KLHDC7A KLHDC7A 127707 kelch domain containing 7A [Source:HGNC Symbol;Acc:HGNC:26791] protein_coding
ENSG00000121281 248.941858 1.130612 0.1178846 9.590836 0.0000000 0.0000000 ENSG00000121281.13 H3BQ93 ADCY7 ADCY7 113 adenylate cyclase 7 [Source:HGNC Symbol;Acc:HGNC:238] protein_coding
ENSG00000269837 193.184408 1.284389 0.1340439 9.581853 0.0000000 0.0000000 ENSG00000269837.2 IPO5P1 NA importin 5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49687] transcribed_processed_pseudogene
ENSG00000119938 145.532986 1.537137 0.1606322 9.569298 0.0000000 0.0000000 ENSG00000119938.9 Q9UQK1 PPP1R3C PPP1R3C 5507 protein phosphatase 1 regulatory subunit 3C [Source:HGNC Symbol;Acc:HGNC:9293] protein_coding
ENSG00000100078 80.716038 4.150001 0.4356865 9.525200 0.0000000 0.0000000 ENSG00000100078.4 Q9NZ20 PLA2G3 PLA2G3 50487 phospholipase A2 group III [Source:HGNC Symbol;Acc:HGNC:17934] protein_coding
ENSG00000128965 206.442695 1.506114 0.1596479 9.433968 0.0000000 0.0000000 ENSG00000128965.13 Q9BUX1 CHAC1 CHAC1 79094 ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] protein_coding
ENSG00000148339 310.448595 1.053122 0.1120045 9.402499 0.0000000 0.0000000 ENSG00000148339.13 Q6KCM7 SLC25A25 SLC25A25 114789 solute carrier family 25 member 25 [Source:HGNC Symbol;Acc:HGNC:20663] protein_coding
ENSG00000184304 57.517257 2.570007 0.2753469 9.333705 0.0000000 0.0000000 ENSG00000184304.17 H0YHS9 PRKD1 PRKD1 5587 protein kinase D1 [Source:HGNC Symbol;Acc:HGNC:9407] protein_coding
ENSG00000132170 174.563752 1.390426 0.1493659 9.308857 0.0000000 0.0000000 ENSG00000132170.24 A0A3P3ZKM0 PPARG PPARG 5468 peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] protein_coding
ENSG00000113070 393.736708 1.154825 0.1245445 9.272395 0.0000000 0.0000000 ENSG00000113070.8 Q99075 HBEGF HBEGF 1839 heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] protein_coding
ENSG00000203706 91.657722 1.909876 0.2070661 9.223507 0.0000000 0.0000000 ENSG00000203706.9 SERTAD4-AS1 NA SERTAD4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:32019] lncRNA
ENSG00000111432 36.484598 3.867695 0.4193664 9.222712 0.0000000 0.0000000 ENSG00000111432.5 Q9ULW2 FZD10 FZD10 11211 frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039] protein_coding
ENSG00000276045 255.242807 1.102327 0.1204770 9.149685 0.0000000 0.0000000 ENSG00000276045.4 Q96D31 ORAI1 ORAI1 84876 ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] protein_coding
ENSG00000125089 170.593353 1.412667 0.1544511 9.146371 0.0000000 0.0000000 ENSG00000125089.18 A0A804HJH0 SH3TC1 SH3TC1 54436 SH3 domain and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:26009] protein_coding
ENSG00000168621 38.310366 4.670406 0.5137757 9.090359 0.0000000 0.0000000 ENSG00000168621.15 A0A0C4DGC2 GDNF GDNF 2668 glial cell derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:4232] protein_coding
ENSG00000011201 209.920980 1.177534 0.1301946 9.044415 0.0000000 0.0000000 ENSG00000011201.12 P23352 ANOS1 ANOS1 3730 anosmin 1 [Source:HGNC Symbol;Acc:HGNC:6211] protein_coding
ENSG00000165899 46.180373 5.103746 0.5654202 9.026465 0.0000000 0.0000000 ENSG00000165899.12 H0YIL4 OTOGL OTOGL 283310 otogelin like [Source:HGNC Symbol;Acc:HGNC:26901] protein_coding
ENSG00000124813 281.548608 1.197493 0.1329342 9.008166 0.0000000 0.0000000 ENSG00000124813.23 Q13950 RUNX2 RUNX2 860 RUNX family transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10472] protein_coding
ENSG00000072832 75.162747 2.024170 0.2249544 8.998135 0.0000000 0.0000000 ENSG00000072832.15 Q14194 CRMP1 CRMP1 1400 collapsin response mediator protein 1 [Source:HGNC Symbol;Acc:HGNC:2365] protein_coding
ENSG00000006062 146.203986 1.442136 0.1604156 8.989997 0.0000000 0.0000000 ENSG00000006062.18 Q99558 MAP3K14 MAP3K14 9020 mitogen-activated protein kinase kinase kinase 14 [Source:HGNC Symbol;Acc:HGNC:6853] protein_coding
ENSG00000092621 306.647644 1.120335 0.1247972 8.977241 0.0000000 0.0000000 ENSG00000092621.13 A0A2C9F2M7 PHGDH PHGDH 26227 phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923] protein_coding
ENSG00000074590 418.827029 1.082114 0.1209818 8.944437 0.0000000 0.0000000 ENSG00000074590.14 O60285 NUAK1 NUAK1 9891 NUAK family kinase 1 [Source:HGNC Symbol;Acc:HGNC:14311] protein_coding
ENSG00000196549 51.017189 2.684555 0.3041158 8.827410 0.0000000 0.0000000 ENSG00000196549.13 P08473 MME MME 4311 membrane metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:7154] protein_coding
ENSG00000196639 237.070016 1.104956 0.1252987 8.818575 0.0000000 0.0000000 ENSG00000196639.7 P35367 HRH1 HRH1 3269 histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] protein_coding
ENSG00000204959 149.979785 1.384582 0.1596270 8.673859 0.0000000 0.0000000 ENSG00000204959.4 ARHGEF34P NA Rho guanine nucleotide exchange factor 34, pseudogene [Source:HGNC Symbol;Acc:HGNC:38086] unprocessed_pseudogene
ENSG00000119138 215.015016 1.116532 0.1291689 8.643972 0.0000000 0.0000000 ENSG00000119138.5 A0A024R260 KLF9 KLF9 687 KLF transcription factor 9 [Source:HGNC Symbol;Acc:HGNC:1123] protein_coding
ENSG00000155966 87.289878 1.836939 0.2128612 8.629752 0.0000000 0.0000000 ENSG00000155966.14 P51816 AFF2 AFF2 2334 ALF transcription elongation factor 2 [Source:HGNC Symbol;Acc:HGNC:3776] protein_coding
ENSG00000100889 408.370440 1.138317 0.1331888 8.546639 0.0000000 0.0000000 ENSG00000100889.12 H0YNG4 PCK2 PCK2 5106 phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] protein_coding
ENSG00000113739 184.133204 1.407751 0.1650203 8.530776 0.0000000 0.0000000 ENSG00000113739.11 Q6FHC9 STC2 STC2 8614 stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] protein_coding
ENSG00000182580 245.396789 1.123552 0.1317572 8.527443 0.0000000 0.0000000 ENSG00000182580.3 P54753 EPHB3 EPHB3 2049 EPH receptor B3 [Source:HGNC Symbol;Acc:HGNC:3394] protein_coding
ENSG00000127946 141.767641 1.321581 0.1552626 8.511906 0.0000000 0.0000000 ENSG00000127946.17 C9JMG5 HIP1 HIP1 3092 huntingtin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:4913] protein_coding
ENSG00000154310 267.831668 1.046011 0.1229625 8.506752 0.0000000 0.0000000 ENSG00000154310.17 Q9UKE5 TNIK TNIK 23043 TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:HGNC:30765] protein_coding
ENSG00000165125 47.264062 3.458707 0.4091415 8.453572 0.0000000 0.0000000 ENSG00000165125.22 C9J9W0 TRPV6 TRPV6 55503 transient receptor potential cation channel subfamily V member 6 [Source:HGNC Symbol;Acc:HGNC:14006] protein_coding
ENSG00000168899 62.688166 2.148135 0.2541945 8.450755 0.0000000 0.0000000 ENSG00000168899.5 O95183 VAMP5 VAMP5 10791 vesicle associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:12646] protein_coding
ENSG00000133067 29.084190 4.402707 0.5221655 8.431631 0.0000000 0.0000000 ENSG00000133067.18 Q9HBX8 LGR6 LGR6 59352 leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719] protein_coding
ENSG00000128165 129.316604 1.615961 0.1920043 8.416273 0.0000000 0.0000000 ENSG00000128165.9 Q7Z4H4 ADM2 ADM2 79924 adrenomedullin 2 [Source:HGNC Symbol;Acc:HGNC:28898] protein_coding
ENSG00000101000 51.141016 2.477558 0.2947172 8.406560 0.0000000 0.0000000 ENSG00000101000.6 A0A0U1RRC4 PROCR PROCR 10544 protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] protein_coding
ENSG00000140279 1733.105258 1.270309 0.1516328 8.377539 0.0000000 0.0000000 ENSG00000140279.13 Q9NRD8 DUOX2 DUOX2 50506 dual oxidase 2 [Source:HGNC Symbol;Acc:HGNC:13273] protein_coding
ENSG00000134262 190.332759 1.208815 0.1445557 8.362281 0.0000000 0.0000000 ENSG00000134262.14 Q9Y6B7 AP4B1 AP4B1 10717 adaptor related protein complex 4 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:572] protein_coding
ENSG00000256870 167.124294 1.803834 0.2168594 8.317990 0.0000000 0.0000000 ENSG00000256870.3 Q8N695 SLC5A8 SLC5A8 160728 solute carrier family 5 member 8 [Source:HGNC Symbol;Acc:HGNC:19119] protein_coding
ENSG00000159231 71.742967 1.925860 0.2322244 8.293100 0.0000000 0.0000000 ENSG00000159231.6 O75828 CBR3 CBR3 874 carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549] protein_coding
ENSG00000142619 27.201255 3.837619 0.4632650 8.283852 0.0000000 0.0000000 ENSG00000142619.4 Q9ULW8 PADI3 PADI3 51702 peptidyl arginine deiminase 3 [Source:HGNC Symbol;Acc:HGNC:18337] protein_coding
ENSG00000161955 249.811216 1.089616 0.1315459 8.283164 0.0000000 0.0000000 ENSG00000161955.17 Q2QBA2 TNFSF13 TNFSF13 8741 TNF superfamily member 13 [Source:HGNC Symbol;Acc:HGNC:11928] protein_coding
ENSG00000188042 264.658159 1.066966 0.1290161 8.270023 0.0000000 0.0000000 ENSG00000188042.8 P56559 ARL4C ARL4C 10123 ADP ribosylation factor like GTPase 4C [Source:HGNC Symbol;Acc:HGNC:698] protein_coding
ENSG00000178726 212.516615 1.282271 0.1554139 8.250685 0.0000000 0.0000000 ENSG00000178726.7 P07204 THBD THBD 7056 thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] protein_coding
ENSG00000115756 127.023078 1.398354 0.1695083 8.249475 0.0000000 0.0000000 ENSG00000115756.13 Q6FGY1 HPCAL1 HPCAL1 3241 hippocalcin like 1 [Source:HGNC Symbol;Acc:HGNC:5145] protein_coding
ENSG00000198873 50.846771 2.565646 0.3115344 8.235513 0.0000000 0.0000000 ENSG00000198873.12 P34947 GRK5 GRK5 2869 G protein-coupled receptor kinase 5 [Source:HGNC Symbol;Acc:HGNC:4544] protein_coding
ENSG00000165507 179.917699 1.197414 0.1463153 8.183792 0.0000000 0.0000000 ENSG00000165507.9 Q9NTK1 DEPP1 DEPP1 11067 DEPP autophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:23355] protein_coding
ENSG00000157833 38.459159 2.920816 0.3590154 8.135628 0.0000000 0.0000000 ENSG00000157833.13 Q75VX8 GAREM2 GAREM2 150946 GRB2 associated regulator of MAPK1 subtype 2 [Source:HGNC Symbol;Acc:HGNC:27172] protein_coding
ENSG00000132334 228.467942 1.019306 0.1256794 8.110368 0.0000000 0.0000000 ENSG00000132334.17 S4R3X3 PTPRE PTPRE 5791 protein tyrosine phosphatase receptor type E [Source:HGNC Symbol;Acc:HGNC:9669] protein_coding
ENSG00000156218 230.605560 1.006888 0.1242190 8.105747 0.0000000 0.0000000 ENSG00000156218.13 P82987 ADAMTSL3 ADAMTSL3 57188 ADAMTS like 3 [Source:HGNC Symbol;Acc:HGNC:14633] protein_coding
ENSG00000246250 56.946035 1.997910 0.2471833 8.082709 0.0000000 0.0000000 ENSG00000246250.3 NA novel transcript lncRNA
ENSG00000165233 188.493506 1.121373 0.1387768 8.080404 0.0000000 0.0000000 ENSG00000165233.18 Q96LW7 CARD19 CARD19 84270 caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] protein_coding
ENSG00000224420 31.116397 4.549617 0.5643530 8.061651 0.0000000 0.0000000 ENSG00000224420.4 C9JUS6 ADM5 ADM5 199800 adrenomedullin 5 (putative) [Source:HGNC Symbol;Acc:HGNC:27293] protein_coding
ENSG00000163053 141.448750 1.347712 0.1673355 8.053956 0.0000000 0.0000000 ENSG00000163053.11 Q7RTX9 SLC16A14 SLC16A14 151473 solute carrier family 16 member 14 [Source:HGNC Symbol;Acc:HGNC:26417] protein_coding
ENSG00000160326 143.089433 1.612808 0.2012830 8.012636 0.0000000 0.0000000 ENSG00000160326.14 Q9UGQ3 SLC2A6 SLC2A6 11182 solute carrier family 2 member 6 [Source:HGNC Symbol;Acc:HGNC:11011] protein_coding
ENSG00000146054 123.634679 1.467590 0.1841648 7.968893 0.0000000 0.0000000 ENSG00000146054.18 Q9C029 TRIM7 TRIM7 81786 tripartite motif containing 7 [Source:HGNC Symbol;Acc:HGNC:16278] protein_coding
ENSG00000168497 130.554034 1.229575 0.1545003 7.958401 0.0000000 0.0000000 ENSG00000168497.5 O95810 CAVIN2 CAVIN2 8436 caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] protein_coding
ENSG00000244198 43.728091 2.594947 0.3277269 7.918017 0.0000000 0.0000000 ENSG00000244198.7 ARHGEF35-AS1 NA ARHGEF35 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41292] lncRNA
ENSG00000225434 169.113504 1.138915 0.1443790 7.888372 0.0000000 0.0000000 ENSG00000225434.5 LINC01504 100507540 long intergenic non-protein coding RNA 1504 [Source:HGNC Symbol;Acc:HGNC:51185] lncRNA
ENSG00000068079 206.479124 1.065286 0.1360569 7.829708 0.0000000 0.0000000 ENSG00000068079.8 P80217 IFI35 IFI35 3430 interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] protein_coding
ENSG00000184113 42.504105 5.875678 0.7542655 7.789933 0.0000000 0.0000000 ENSG00000184113.10 O00501 CLDN5 CLDN5 7122 claudin 5 [Source:HGNC Symbol;Acc:HGNC:2047] protein_coding
ENSG00000169213 152.213603 1.158458 0.1489779 7.776040 0.0000000 0.0000000 ENSG00000169213.7 P20337 RAB3B RAB3B 5865 RAB3B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9778] protein_coding
ENSG00000142273 199.416947 1.028779 0.1327617 7.749067 0.0000000 0.0000000 ENSG00000142273.13 Q9ULV8 CBLC CBLC 23624 Cbl proto-oncogene C [Source:HGNC Symbol;Acc:HGNC:15961] protein_coding
ENSG00000176697 35.459100 2.536808 0.3279022 7.736477 0.0000000 0.0000000 ENSG00000176697.20 P23560 BDNF BDNF 627 brain derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:1033] protein_coding
ENSG00000223784 70.968096 2.101236 0.2723808 7.714331 0.0000000 0.0000000 ENSG00000223784.2 LINP1 NA lncRNA in non-homologous end joining pathway 1 [Source:HGNC Symbol;Acc:HGNC:53170] lncRNA
ENSG00000107518 26.034677 3.169351 0.4127939 7.677803 0.0000000 0.0000000 ENSG00000107518.18 Q5VV63 ATRNL1 ATRNL1 26033 attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063] protein_coding
ENSG00000146858 142.066540 1.172136 0.1542353 7.599660 0.0000000 0.0000000 ENSG00000146858.8 Q96H79 ZC3HAV1L ZC3HAV1L 92092 zinc finger CCCH-type containing, antiviral 1 like [Source:HGNC Symbol;Acc:HGNC:22423] protein_coding
ENSG00000169174 349.057488 1.016178 0.1337458 7.597833 0.0000000 0.0000000 ENSG00000169174.12 A0A669KAY4 PCSK9 PCSK9 255738 proprotein convertase subtilisin/kexin type 9 [Source:HGNC Symbol;Acc:HGNC:20001] protein_coding
ENSG00000179241 206.360125 1.024366 0.1355085 7.559423 0.0000000 0.0000000 ENSG00000179241.13 Q86YD5 LDLRAD3 LDLRAD3 143458 low density lipoprotein receptor class A domain containing 3 [Source:HGNC Symbol;Acc:HGNC:27046] protein_coding
ENSG00000143882 76.268382 1.643769 0.2186540 7.517671 0.0000000 0.0000000 ENSG00000143882.12 Q8NEY4 ATP6V1C2 ATP6V1C2 245973 ATPase H+ transporting V1 subunit C2 [Source:HGNC Symbol;Acc:HGNC:18264] protein_coding
ENSG00000177494 136.585006 1.261787 0.1686350 7.482356 0.0000000 0.0000000 ENSG00000177494.6 Q9BTP6 ZBED2 ZBED2 79413 zinc finger BED-type containing 2 [Source:HGNC Symbol;Acc:HGNC:20710] protein_coding
ENSG00000114378 77.818016 1.975390 0.2641339 7.478744 0.0000000 0.0000000 ENSG00000114378.17 C9JRK1 HYAL1 HYAL1 3373 hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:5320] protein_coding
ENSG00000198400 54.359739 8.907568 1.1957060 7.449630 0.0000000 0.0000000 ENSG00000198400.14 A0A6Q8PF65 NTRK1 NTRK1 4914 neurotrophic receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:8031] protein_coding
ENSG00000123405 27.154316 3.440923 0.4627956 7.435083 0.0000000 0.0000000 ENSG00000123405.14 A8K3E0 NFE2 NFE2 4778 nuclear factor, erythroid 2 [Source:HGNC Symbol;Acc:HGNC:7780] protein_coding
ENSG00000172345 144.924450 1.092450 0.1477371 7.394554 0.0000000 0.0000000 ENSG00000172345.14 Q9NSY2 STARD5 STARD5 80765 StAR related lipid transfer domain containing 5 [Source:HGNC Symbol;Acc:HGNC:18065] protein_coding
ENSG00000258689 86.610058 1.506960 0.2073405 7.268047 0.0000000 0.0000000 ENSG00000258689.2 LINC01269 103695436 long intergenic non-protein coding RNA 1269 [Source:HGNC Symbol;Acc:HGNC:50325] lncRNA
ENSG00000164088 61.619806 1.768467 0.2438144 7.253330 0.0000000 0.0000000 ENSG00000164088.18 Q96MI6 PPM1M PPM1M 132160 protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] protein_coding
ENSG00000162366 552.955602 1.071035 0.1484592 7.214343 0.0000000 0.0000000 ENSG00000162366.8 Q13113 PDZK1IP1 PDZK1IP1 10158 PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] protein_coding
ENSG00000164509 123.933087 1.279525 0.1804370 7.091255 0.0000000 0.0000000 ENSG00000164509.16 A0A494C190 IL31RA IL31RA 133396 interleukin 31 receptor A [Source:HGNC Symbol;Acc:HGNC:18969] protein_coding
ENSG00000105641 36.224941 3.520320 0.4976070 7.074498 0.0000000 0.0000000 ENSG00000105641.4 Q92911 SLC5A5 SLC5A5 6528 solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] protein_coding
ENSG00000018236 244.021960 1.042478 0.1474988 7.067705 0.0000000 0.0000000 ENSG00000018236.15 A0A024R104 CNTN1 CNTN1 1272 contactin 1 [Source:HGNC Symbol;Acc:HGNC:2171] protein_coding
ENSG00000110693 148.936565 1.150795 0.1631060 7.055508 0.0000000 0.0000000 ENSG00000110693.19 P35712 SOX6 SOX6 55553 SRY-box transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:16421] protein_coding
ENSG00000185052 28.437320 2.851837 0.4060242 7.023811 0.0000000 0.0000000 ENSG00000185052.13 Q9HC58 SLC24A3 SLC24A3 57419 solute carrier family 24 member 3 [Source:HGNC Symbol;Acc:HGNC:10977] protein_coding
ENSG00000113119 138.965314 1.042472 0.1492390 6.985252 0.0000000 0.0000000 ENSG00000113119.13 D6R986 TMCO6 TMCO6 55374 transmembrane and coiled-coil domains 6 [Source:HGNC Symbol;Acc:HGNC:28814] protein_coding
ENSG00000184160 32.783144 3.813250 0.5464739 6.977919 0.0000000 0.0000000 ENSG00000184160.8 P18825 ADRA2C ADRA2C 152 adrenoceptor alpha 2C [Source:HGNC Symbol;Acc:HGNC:283] protein_coding
ENSG00000040608 61.052075 1.898300 0.2734200 6.942797 0.0000000 0.0000000 ENSG00000040608.14 Q9BZR6 RTN4R RTN4R 65078 reticulon 4 receptor [Source:HGNC Symbol;Acc:HGNC:18601] protein_coding
ENSG00000113361 1812.776888 1.369401 0.1988331 6.887189 0.0000000 0.0000000 ENSG00000113361.13 P55285 CDH6 CDH6 1004 cadherin 6 [Source:HGNC Symbol;Acc:HGNC:1765] protein_coding
ENSG00000112195 50.789635 8.129060 1.1932859 6.812332 0.0000000 0.0000000 ENSG00000112195.9 Q5T2D2 TREML2 TREML2 79865 triggering receptor expressed on myeloid cells like 2 [Source:HGNC Symbol;Acc:HGNC:21092] protein_coding
ENSG00000162551 148.270545 1.165912 0.1713830 6.802964 0.0000000 0.0000000 ENSG00000162551.14 A0A024RAB4 ALPL ALPL 249 alkaline phosphatase, biomineralization associated [Source:HGNC Symbol;Acc:HGNC:438] protein_coding
ENSG00000151490 17.514277 4.326711 0.6368834 6.793569 0.0000000 0.0000000 ENSG00000151490.15 Q16827 PTPRO PTPRO 5800 protein tyrosine phosphatase receptor type O [Source:HGNC Symbol;Acc:HGNC:9678] protein_coding
ENSG00000182601 22.167484 3.208751 0.4741769 6.766991 0.0000000 0.0000000 ENSG00000182601.7 Q9Y661 HS3ST4 HS3ST4 9951 heparan sulfate-glucosamine 3-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:5200] protein_coding
ENSG00000148053 30.647476 2.280145 0.3420191 6.666718 0.0000000 0.0000000 ENSG00000148053.18 A0A8I5KUZ1 NTRK2 NTRK2 4915 neurotrophic receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:8032] protein_coding
ENSG00000104332 35.460564 2.216830 0.3347822 6.621707 0.0000000 0.0000000 ENSG00000104332.12 Q8N474 SFRP1 SFRP1 6422 secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] protein_coding
ENSG00000130222 33.701335 2.100464 0.3193550 6.577206 0.0000000 0.0000000 ENSG00000130222.11 Q5VZ88 GADD45G GADD45G 10912 growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] protein_coding
ENSG00000170373 19.656429 7.761247 1.2219135 6.351716 0.0000000 0.0000000 ENSG00000170373.9 P01037 CST1 CST1 1469 cystatin SN [Source:HGNC Symbol;Acc:HGNC:2473] protein_coding
ENSG00000107485 96.572207 1.174813 0.1877723 6.256585 0.0000000 0.0000000 ENSG00000107485.18 A0A2R8Y2A9 GATA3 GATA3 2625 GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172] protein_coding
ENSG00000121742 55.356677 1.552645 0.2530813 6.134964 0.0000000 0.0000000 ENSG00000121742.19 O95452 GJB6 GJB6 10804 gap junction protein beta 6 [Source:HGNC Symbol;Acc:HGNC:4288] protein_coding
ENSG00000013016 119.910597 1.176821 0.1941001 6.062963 0.0000000 0.0000000 ENSG00000013016.16 Q9NZN3 EHD3 EHD3 30845 EH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:3244] protein_coding
ENSG00000183098 89.469355 1.230130 0.2032009 6.053764 0.0000000 0.0000000 ENSG00000183098.12 Q9Y625 GPC6 GPC6 10082 glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454] protein_coding
ENSG00000104154 72.947310 1.300239 0.2151920 6.042226 0.0000000 0.0000000 ENSG00000104154.7 O14863 SLC30A4 SLC30A4 7782 solute carrier family 30 member 4 [Source:HGNC Symbol;Acc:HGNC:11015] protein_coding
ENSG00000135960 39.880274 1.731579 0.2873637 6.025740 0.0000000 0.0000000 ENSG00000135960.10 Q9UNE0 EDAR EDAR 10913 ectodysplasin A receptor [Source:HGNC Symbol;Acc:HGNC:2895] protein_coding
ENSG00000234147 17.899432 4.767551 0.7932471 6.010171 0.0000000 0.0000000 ENSG00000234147.4 NA novel transcript lncRNA
ENSG00000237975 102.916591 1.187393 0.1979574 5.998227 0.0000000 0.0000000 ENSG00000237975.7 FLG-AS1 339400 FLG antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27913] lncRNA
ENSG00000182472 75.057789 1.310820 0.2186201 5.995880 0.0000000 0.0000000 ENSG00000182472.9 M0QZT6 CAPN12 CAPN12 147968 calpain 12 [Source:HGNC Symbol;Acc:HGNC:13249] protein_coding
ENSG00000173868 11.217035 7.418266 1.2511650 5.929087 0.0000000 0.0000001 ENSG00000173868.12 D6RIT6 PHOSPHO1 PHOSPHO1 162466 phosphoethanolamine/phosphocholine phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:16815] protein_coding
ENSG00000104415 18.820219 4.703846 0.7952836 5.914678 0.0000000 0.0000001 ENSG00000104415.14 E5RG88 CCN4 CCN4 8840 cellular communication network factor 4 [Source:HGNC Symbol;Acc:HGNC:12769] protein_coding
ENSG00000121335 9.750543 7.462419 1.2641925 5.902914 0.0000000 0.0000001 ENSG00000121335.12 P02812 PRB2 PRB2 653247 proline rich protein BstNI subfamily 2 [Source:HGNC Symbol;Acc:HGNC:9338] protein_coding
ENSG00000278910 13.907980 7.264590 1.2336402 5.888743 0.0000000 0.0000001 ENSG00000278910.5 BANCR NA BRAF-activated non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:43877] lncRNA
ENSG00000138311 102.856794 1.048625 0.1789357 5.860344 0.0000000 0.0000001 ENSG00000138311.18 Q70YC5 ZNF365 ZNF365 22891 zinc finger protein 365 [Source:HGNC Symbol;Acc:HGNC:18194] protein_coding
ENSG00000177300 18.052806 2.799786 0.4800743 5.831984 0.0000000 0.0000001 ENSG00000177300.7 Q8N7P3 CLDN22 CLDN22 53842 claudin 22 [Source:HGNC Symbol;Acc:HGNC:2044] protein_coding
ENSG00000147251 89.931324 1.089779 0.1904563 5.721939 0.0000000 0.0000002 ENSG00000147251.16 Q5JSL3 DOCK11 DOCK11 139818 dedicator of cytokinesis 11 [Source:HGNC Symbol;Acc:HGNC:23483] protein_coding
ENSG00000234965 14.775275 2.903469 0.5087727 5.706810 0.0000000 0.0000002 ENSG00000234965.3 B8ZZ34 SHISA8 SHISA8 440829 shisa family member 8 [Source:HGNC Symbol;Acc:HGNC:18351] protein_coding
ENSG00000147155 160.927658 1.126321 0.1984252 5.676299 0.0000000 0.0000002 ENSG00000147155.11 A0A024QYX0 EBP EBP 10682 EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] protein_coding
ENSG00000127951 20.513199 6.879109 1.2144963 5.664166 0.0000000 0.0000002 ENSG00000127951.8 A4D1B8 FGL2 FGL2 10875 fibrinogen like 2 [Source:HGNC Symbol;Acc:HGNC:3696] protein_coding
ENSG00000141540 31.790091 1.963762 0.3479023 5.644579 0.0000000 0.0000003 ENSG00000141540.11 B4DKD1 TTYH2 TTYH2 94015 tweety family member 2 [Source:HGNC Symbol;Acc:HGNC:13877] protein_coding
ENSG00000166924 16.939107 2.810351 0.4985780 5.636732 0.0000000 0.0000003 ENSG00000166924.9 C9JS30 NYAP1 NYAP1 222950 neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 [Source:HGNC Symbol;Acc:HGNC:22009] protein_coding
ENSG00000132773 91.724890 1.037135 0.1852203 5.599467 0.0000000 0.0000003 ENSG00000132773.12 Q96GM8 TOE1 TOE1 114034 target of EGR1, exonuclease [Source:HGNC Symbol;Acc:HGNC:15954] protein_coding
ENSG00000231106 37.426227 1.865159 0.3350837 5.566249 0.0000000 0.0000004 ENSG00000231106.3 LINC01436 NA long intergenic non-protein coding RNA 1436 [Source:HGNC Symbol;Acc:HGNC:50754] lncRNA
ENSG00000232977 15.526673 3.415338 0.6152782 5.550885 0.0000000 0.0000004 ENSG00000232977.7 LINC00327 100506697 long intergenic non-protein coding RNA 327 [Source:HGNC Symbol;Acc:HGNC:42009] lncRNA
ENSG00000167992 23.552460 2.182098 0.3932242 5.549246 0.0000000 0.0000004 ENSG00000167992.14 B4DY31 VWCE VWCE 220001 von Willebrand factor C and EGF domains [Source:HGNC Symbol;Acc:HGNC:26487] protein_coding
ENSG00000164451 15.160270 6.782948 1.2286433 5.520681 0.0000000 0.0000005 ENSG00000164451.14 Q5JW98 CALHM4 CALHM4 221301 calcium homeostasis modulator family member 4 [Source:HGNC Symbol;Acc:HGNC:21094] protein_coding
ENSG00000215424 87.277528 1.234108 0.2238680 5.512659 0.0000000 0.0000005 ENSG00000215424.10 MCM3AP-AS1 114044 MCM3AP antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:16417] lncRNA
ENSG00000160191 124.648614 1.058634 0.1921327 5.509910 0.0000000 0.0000005 ENSG00000160191.18 O76083 PDE9A PDE9A 5152 phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795] protein_coding
ENSG00000215853 26.845844 2.647595 0.4826703 5.485309 0.0000000 0.0000006 ENSG00000215853.3 Q6XPR3 RPTN RPTN 126638 repetin [Source:HGNC Symbol;Acc:HGNC:26809] protein_coding
ENSG00000007129 10.458824 6.875437 1.2562248 5.473095 0.0000000 0.0000006 ENSG00000007129.18 Q3KPI0 CEACAM21 CEACAM21 90273 CEA cell adhesion molecule 21 [Source:HGNC Symbol;Acc:HGNC:28834] protein_coding
ENSG00000162873 34.522303 1.626672 0.2996051 5.429387 0.0000001 0.0000008 ENSG00000162873.15 U3KPX9 KLHDC8A KLHDC8A 55220 kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] protein_coding
ENSG00000112769 51.747930 1.343967 0.2492915 5.391147 0.0000001 0.0000010 ENSG00000112769.20 A0A494C139 LAMA4 LAMA4 3910 laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484] protein_coding
ENSG00000181577 311.753868 1.013878 0.1898830 5.339492 0.0000001 0.0000013 ENSG00000181577.16 LINC03040 221416 long intergenic non-protein coding RNA 3040 [Source:HGNC Symbol;Acc:HGNC:28692] lncRNA
ENSG00000257242 44.934216 1.534646 0.2929365 5.238836 0.0000002 0.0000021 ENSG00000257242.9 LINC01619 256021 long intergenic non-protein coding RNA 1619 [Source:HGNC Symbol;Acc:HGNC:27409] lncRNA
ENSG00000135045 50.350740 1.354744 0.2596689 5.217199 0.0000002 0.0000024 ENSG00000135045.7 Q8IXQ3 C9orf40 C9orf40 55071 chromosome 9 open reading frame 40 [Source:HGNC Symbol;Acc:HGNC:23433] protein_coding
ENSG00000114279 63.583000 1.222126 0.2369094 5.158622 0.0000002 0.0000032 ENSG00000114279.15 C9JIN3 FGF12 FGF12 2257 fibroblast growth factor 12 [Source:HGNC Symbol;Acc:HGNC:3668] protein_coding
ENSG00000284428 89.228968 1.060430 0.2071355 5.119497 0.0000003 0.0000039 ENSG00000284428.1 NA novel transcript lncRNA
ENSG00000174502 44.345742 1.847146 0.3608549 5.118806 0.0000003 0.0000039 ENSG00000174502.19 Q7LBE3 SLC26A9 SLC26A9 115019 solute carrier family 26 member 9 [Source:HGNC Symbol;Acc:HGNC:14469] protein_coding
ENSG00000148488 70.263346 1.172306 0.2292387 5.113910 0.0000003 0.0000040 ENSG00000148488.17 P61647 ST8SIA6 ST8SIA6 338596 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:23317] protein_coding
ENSG00000225177 47.516704 1.407396 0.2766140 5.087943 0.0000004 0.0000045 ENSG00000225177.6 NHSL1-AS1 124900217 NHSL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40947] lncRNA
ENSG00000266729 12.124074 3.359247 0.6638332 5.060379 0.0000004 0.0000052 ENSG00000266729.5 DSG1-AS1 101927718 DSG1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51115] lncRNA
ENSG00000171476 45.407356 1.835768 0.3644113 5.037627 0.0000005 0.0000058 ENSG00000171476.23 Q9BPY8 HOPX HOPX 84525 HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961] protein_coding
ENSG00000251493 77.322154 1.133169 0.2251312 5.033373 0.0000005 0.0000059 ENSG00000251493.5 Q16676 FOXD1 FOXD1 2297 forkhead box D1 [Source:HGNC Symbol;Acc:HGNC:3802] protein_coding
ENSG00000142156 30.443561 1.862675 0.3702330 5.031089 0.0000005 0.0000059 ENSG00000142156.16 P12109 COL6A1 COL6A1 1291 collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] protein_coding
ENSG00000170608 10.559893 3.860991 0.7756836 4.977533 0.0000006 0.0000076 ENSG00000170608.3 M0QZW5 FOXA3 FOXA3 3171 forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023] protein_coding
ENSG00000255521 12.389747 3.470381 0.7016934 4.945723 0.0000008 0.0000089 ENSG00000255521.3 CD44-DT 100507144 CD44 divergent transcript [Source:HGNC Symbol;Acc:HGNC:56175] lncRNA
ENSG00000099954 50.884208 1.248599 0.2540648 4.914488 0.0000009 0.0000103 ENSG00000099954.19 B7WPH3 CECR2 CECR2 27443 CECR2 histone acetyl-lysine reader [Source:HGNC Symbol;Acc:HGNC:1840] protein_coding
ENSG00000280219 21.709831 2.118037 0.4323576 4.898808 0.0000010 0.0000111 ENSG00000280219.1 NA TEC TEC
ENSG00000126545 12.294394 5.278056 1.0949018 4.820575 0.0000014 0.0000160 ENSG00000126545.14 P47710 CSN1S1 CSN1S1 1446 casein alpha s1 [Source:HGNC Symbol;Acc:HGNC:2445] protein_coding
ENSG00000159640 18.505798 2.073146 0.4310700 4.809303 0.0000015 0.0000169 ENSG00000159640.17 P12821 ACE ACE 1636 angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] protein_coding
ENSG00000165646 6.272255 6.270580 1.3044758 4.806973 0.0000015 0.0000170 ENSG00000165646.14 Q05940 SLC18A2 SLC18A2 6571 solute carrier family 18 member A2 [Source:HGNC Symbol;Acc:HGNC:10935] protein_coding
ENSG00000288018 29.042260 1.757314 0.3671597 4.786239 0.0000017 0.0000187 ENSG00000288018.3 101929174 novel transcript lncRNA
ENSG00000198650 12.231587 2.711636 0.5683357 4.771187 0.0000018 0.0000201 ENSG00000198650.11 P17735 TAT TAT 6898 tyrosine aminotransferase [Source:HGNC Symbol;Acc:HGNC:11573] protein_coding
ENSG00000167748 18.190540 1.948245 0.4139260 4.706746 0.0000025 0.0000271 ENSG00000167748.11 P06870 KLK1 KLK1 3816 kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] protein_coding
ENSG00000100344 89.280469 1.667261 0.3549632 4.696998 0.0000026 0.0000283 ENSG00000100344.11 F8W8E5 PNPLA3 PNPLA3 80339 patatin like phospholipase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18590] protein_coding
ENSG00000132846 71.331969 1.053370 0.2245100 4.691859 0.0000027 0.0000289 ENSG00000132846.6 D6RIC4 ZBED3 ZBED3 84327 zinc finger BED-type containing 3 [Source:HGNC Symbol;Acc:HGNC:20711] protein_coding
ENSG00000204869 11.075262 3.453421 0.7429592 4.648198 0.0000033 0.0000352 ENSG00000204869.9 Q6B9Z1 IGFL4 IGFL4 444882 IGF like family member 4 [Source:HGNC Symbol;Acc:HGNC:32931] protein_coding
ENSG00000134242 17.855203 2.320229 0.5001120 4.639419 0.0000035 0.0000366 ENSG00000134242.16 E9PMK2 PTPN22 PTPN22 26191 protein tyrosine phosphatase non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652] protein_coding
ENSG00000198829 12.956012 2.552570 0.5515540 4.627961 0.0000037 0.0000386 ENSG00000198829.6 Q9BXA5 SUCNR1 SUCNR1 56670 succinate receptor 1 [Source:HGNC Symbol;Acc:HGNC:4542] protein_coding
ENSG00000257594 20.805862 2.003412 0.4345003 4.610841 0.0000040 0.0000416 ENSG00000257594.4 Q8N4A0 GALNT4 GALNT4 8693 polypeptide N-acetylgalactosaminyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:4126] protein_coding
ENSG00000135063 61.335794 1.015099 0.2213755 4.585417 0.0000045 0.0000464 ENSG00000135063.20 A0A0A0MRU1 ENTREP1 ENTREP1 9413 endosomal transmembrane epsin interactor 1 [Source:HGNC Symbol;Acc:HGNC:24820] protein_coding
ENSG00000285108 50.408409 1.578154 0.3469467 4.548694 0.0000054 0.0000544 ENSG00000285108.1 NA novel transcript lncRNA
ENSG00000078098 92.197264 1.082266 0.2398743 4.511805 0.0000064 0.0000637 ENSG00000078098.15 Q12884 FAP FAP 2191 fibroblast activation protein alpha [Source:HGNC Symbol;Acc:HGNC:3590] protein_coding
ENSG00000164236 68.788940 1.084553 0.2412047 4.496401 0.0000069 0.0000683 ENSG00000164236.12 A6NCL7 ANKRD33B ANKRD33B 651746 ankyrin repeat domain 33B [Source:HGNC Symbol;Acc:HGNC:35240] protein_coding
ENSG00000164849 15.251087 2.074673 0.4625074 4.485709 0.0000073 0.0000711 ENSG00000164849.10 C9J5X5 GPR146 GPR146 115330 G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718] protein_coding
ENSG00000115590 9.274236 3.834496 0.8556088 4.481600 0.0000074 0.0000724 ENSG00000115590.14 P27930 IL1R2 IL1R2 7850 interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] protein_coding
ENSG00000204421 10.729259 4.201780 0.9475992 4.434132 0.0000092 0.0000888 ENSG00000204421.3 O95867 LY6G6C LY6G6C 80740 lymphocyte antigen 6 family member G6C [Source:HGNC Symbol;Acc:HGNC:13936] protein_coding
ENSG00000181444 24.174885 1.598849 0.3626008 4.409393 0.0000104 0.0000987 ENSG00000181444.13 C9JAX3 ZNF467 ZNF467 168544 zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] protein_coding
ENSG00000093009 16.549652 2.092042 0.4776763 4.379622 0.0000119 0.0001120 ENSG00000093009.11 O75419 CDC45 CDC45 8318 cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] protein_coding
ENSG00000204839 44.410817 1.212915 0.2773309 4.373528 0.0000122 0.0001149 ENSG00000204839.9 A6NGR9 MROH6 MROH6 642475 maestro heat like repeat family member 6 [Source:HGNC Symbol;Acc:HGNC:27814] protein_coding
ENSG00000233569 15.896971 2.167176 0.5022155 4.315232 0.0000159 0.0001470 ENSG00000233569.2 101928797 novel transcript lncRNA
ENSG00000059377 38.886152 1.496682 0.3481700 4.298709 0.0000172 0.0001575 ENSG00000059377.19 C9JS68 TBXAS1 TBXAS1 6916 thromboxane A synthase 1 [Source:HGNC Symbol;Acc:HGNC:11609] protein_coding
ENSG00000095596 35.728605 1.147780 0.2683277 4.277532 0.0000189 0.0001721 ENSG00000095596.12 O43174 CYP26A1 CYP26A1 1592 cytochrome P450 family 26 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2603] protein_coding
ENSG00000088826 62.322965 1.014044 0.2410244 4.207227 0.0000259 0.0002290 ENSG00000088826.18 Q9NWM0 SMOX SMOX 54498 spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862] protein_coding
ENSG00000284644 12.781003 2.454374 0.5839194 4.203276 0.0000263 0.0002324 ENSG00000284644.1 NA novel transcript, antisense to OR2A1 and ARHGEF5 lncRNA
ENSG00000187122 55.246575 1.002548 0.2392946 4.189598 0.0000279 0.0002457 ENSG00000187122.17 O75093 SLIT1 SLIT1 6585 slit guidance ligand 1 [Source:HGNC Symbol;Acc:HGNC:11085] protein_coding
ENSG00000001630 68.042902 1.260398 0.3054362 4.126550 0.0000368 0.0003161 ENSG00000001630.18 Q16850 CYP51A1 CYP51A1 1595 cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649] protein_coding
ENSG00000146006 8.155003 2.803932 0.6824560 4.108590 0.0000398 0.0003391 ENSG00000146006.8 O43300 LRRTM2 LRRTM2 26045 leucine rich repeat transmembrane neuronal 2 [Source:HGNC Symbol;Acc:HGNC:19409] protein_coding
ENSG00000237167 10.849500 2.395984 0.5838631 4.103674 0.0000407 0.0003454 ENSG00000237167.1 NA novel transcript lncRNA
ENSG00000105880 8.739451 3.271076 0.8004677 4.086455 0.0000438 0.0003690 ENSG00000105880.7 P56178 DLX5 DLX5 1749 distal-less homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2918] protein_coding
ENSG00000225975 37.912072 1.150060 0.2816550 4.083222 0.0000444 0.0003728 ENSG00000225975.8 ZNF567-DT 101927621 ZNF567 divergent transcript [Source:HGNC Symbol;Acc:HGNC:51281] lncRNA
ENSG00000137561 14.755824 1.842420 0.4563443 4.037347 0.0000541 0.0004462 ENSG00000137561.5 P49638 TTPA TTPA 7274 alpha tocopherol transfer protein [Source:HGNC Symbol;Acc:HGNC:12404] protein_coding
ENSG00000231993 45.713036 1.074103 0.2677544 4.011523 0.0000603 0.0004929 ENSG00000231993.2 EP300-AS1 NA EP300 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50504] lncRNA
ENSG00000087303 28.829676 1.463337 0.3661402 3.996656 0.0000642 0.0005227 ENSG00000087303.19 Q14112 NID2 NID2 22795 nidogen 2 [Source:HGNC Symbol;Acc:HGNC:13389] protein_coding
ENSG00000179546 13.783441 2.226206 0.5572863 3.994726 0.0000648 0.0005260 ENSG00000179546.5 P28221 HTR1D HTR1D 3352 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] protein_coding
ENSG00000044524 12.380063 2.070073 0.5203144 3.978504 0.0000694 0.0005591 ENSG00000044524.11 C9JXA2 EPHA3 EPHA3 2042 EPH receptor A3 [Source:HGNC Symbol;Acc:HGNC:3387] protein_coding
ENSG00000167419 22.701385 1.894542 0.4791995 3.953555 0.0000770 0.0006157 ENSG00000167419.11 F5H386 LPO LPO 4025 lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] protein_coding
ENSG00000135643 24.283800 1.390106 0.3534509 3.932953 0.0000839 0.0006670 ENSG00000135643.5 Q86W47 KCNMB4 KCNMB4 27345 potassium calcium-activated channel subfamily M regulatory beta subunit 4 [Source:HGNC Symbol;Acc:HGNC:6289] protein_coding
ENSG00000221887 11.736873 2.294976 0.5896381 3.892177 0.0000993 0.0007795 ENSG00000221887.6 P0C7T4 HMSD HMSD 284293 histocompatibility minor serpin domain containing [Source:HGNC Symbol;Acc:HGNC:23037] protein_coding
ENSG00000248587 8.426787 3.407272 0.8850735 3.849706 0.0001183 0.0009100 ENSG00000248587.8 GDNF-AS1 NA GDNF antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43592] lncRNA
ENSG00000115165 7.385393 3.362223 0.8814489 3.814427 0.0001365 0.0010386 ENSG00000115165.10 O60759 CYTIP CYTIP 9595 cytohesin 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:9506] protein_coding
ENSG00000167105 45.068217 1.110469 0.2918810 3.804526 0.0001421 0.0010768 ENSG00000167105.8 Q6UXU6 TMEM92 TMEM92 162461 transmembrane protein 92 [Source:HGNC Symbol;Acc:HGNC:26579] protein_coding
ENSG00000170379 26.926917 1.327891 0.3563866 3.725983 0.0001946 0.0014350 ENSG00000170379.21 A6NFQ2 TCAF2 TCAF2 285966 TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878] protein_coding
ENSG00000234380 17.836085 1.623665 0.4378602 3.708181 0.0002088 0.0015282 ENSG00000234380.3 LINC01426 100506385 long intergenic non-protein coding RNA 1426 [Source:HGNC Symbol;Acc:HGNC:50734] lncRNA
ENSG00000287941 6.372786 3.381066 0.9202212 3.674189 0.0002386 0.0017181 ENSG00000287941.1 NA novel transcript lncRNA
ENSG00000115325 18.279877 1.552688 0.4246502 3.656394 0.0002558 0.0018261 ENSG00000115325.14 Q99704 DOK1 DOK1 1796 docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990] protein_coding
ENSG00000197921 16.201431 1.644877 0.4510377 3.646872 0.0002655 0.0018867 ENSG00000197921.6 Q5TA89 HES5 HES5 388585 hes family bHLH transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:19764] protein_coding
ENSG00000112562 10.433946 1.988210 0.5466817 3.636869 0.0002760 0.0019489 ENSG00000112562.20 Q9H3U7 SMOC2 SMOC2 64094 SPARC related modular calcium binding 2 [Source:HGNC Symbol;Acc:HGNC:20323] protein_coding
ENSG00000188404 34.418413 1.478358 0.4079004 3.624311 0.0002897 0.0020355 ENSG00000188404.10 P14151 SELL SELL 6402 selectin L [Source:HGNC Symbol;Acc:HGNC:10720] protein_coding
ENSG00000185352 6.424647 3.501886 0.9795138 3.575127 0.0003501 0.0024035 ENSG00000185352.10 Q8IZP7 HS6ST3 HS6ST3 266722 heparan sulfate 6-O-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:19134] protein_coding
ENSG00000243244 33.072852 1.116564 0.3145129 3.550139 0.0003850 0.0026211 ENSG00000243244.7 Q9Y6Q2 STON1 STON1 11037 stonin 1 [Source:HGNC Symbol;Acc:HGNC:17003] protein_coding
ENSG00000119686 21.046513 1.402863 0.3959447 3.543078 0.0003955 0.0026861 ENSG00000119686.10 G3V391 FLVCR2 FLVCR2 55640 FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105] protein_coding
ENSG00000189419 7.813290 2.654503 0.7556516 3.512866 0.0004433 0.0029718 ENSG00000189419.8 SPATA41 NA spermatogenesis associated 41 [Source:HGNC Symbol;Acc:HGNC:48613] lncRNA
ENSG00000101336 14.676680 1.535109 0.4381170 3.503880 0.0004585 0.0030636 ENSG00000101336.18 H7BXG4 HCK HCK 3055 HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] protein_coding
ENSG00000275552 14.639784 2.056063 0.5901325 3.484071 0.0004938 0.0032807 ENSG00000275552.1 NA novel transcript, antisense ABHD4 lncRNA
ENSG00000154548 16.072852 1.670854 0.4807807 3.475294 0.0005103 0.0033759 ENSG00000154548.9 Q8WXF0 SRSF12 SRSF12 135295 serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] protein_coding
ENSG00000185669 27.263515 1.176004 0.3404838 3.453920 0.0005525 0.0036103 ENSG00000185669.6 Q3KNW1 SNAI3 SNAI3 333929 snail family transcriptional repressor 3 [Source:HGNC Symbol;Acc:HGNC:18411] protein_coding
ENSG00000244479 6.171695 3.412589 0.9881082 3.453660 0.0005530 0.0036125 ENSG00000244479.7 OR2A1-AS1 NA OR2A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49168] lncRNA
ENSG00000285763 13.156407 1.724066 0.5074342 3.397614 0.0006798 0.0043482 ENSG00000285763.1 NA novel transcript, antisense to C6orf52 lncRNA
ENSG00000157502 20.666540 1.372794 0.4052730 3.387332 0.0007058 0.0044836 ENSG00000157502.13 Q5H9M0 PWWP3B PWWP3B 139221 PWWP domain containing 3B [Source:HGNC Symbol;Acc:HGNC:26583] protein_coding
ENSG00000186603 5.942231 3.052702 0.9183185 3.324230 0.0008866 0.0054879 ENSG00000186603.7 Q96IR7 HPDL HPDL 84842 4-hydroxyphenylpyruvate dioxygenase like [Source:HGNC Symbol;Acc:HGNC:28242] protein_coding
ENSG00000164037 11.828630 1.955004 0.5966155 3.276824 0.0010498 0.0063608 ENSG00000164037.17 H0Y9Z0 SLC9B1 SLC9B1 150159 solute carrier family 9 member B1 [Source:HGNC Symbol;Acc:HGNC:24244] protein_coding
ENSG00000117016 30.181050 1.137213 0.3476855 3.270808 0.0010724 0.0064694 ENSG00000117016.10 Q9UJD0 RIMS3 RIMS3 9783 regulating synaptic membrane exocytosis 3 [Source:HGNC Symbol;Acc:HGNC:21292] protein_coding
ENSG00000254951 15.961184 1.600553 0.4904781 3.263252 0.0011014 0.0066262 ENSG00000254951.7 283299 novel transcript, sense overlapping OR5P2, OR5P3 and OR5P1P lncRNA
ENSG00000164850 18.879947 1.241290 0.3823917 3.246122 0.0011699 0.0069927 ENSG00000164850.16 A0A024R849 GPR30 GPER1 2852 G protein-coupled estrogen receptor 1 [Source:HGNC Symbol;Acc:HGNC:4485] protein_coding
ENSG00000099256 24.192834 1.203823 0.3718145 3.237697 0.0012050 0.0071684 ENSG00000099256.19 Q9NRG1 PRTFDC1 PRTFDC1 56952 phosphoribosyl transferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23333] protein_coding
ENSG00000264269 9.007572 1.864491 0.5760508 3.236678 0.0012093 0.0071892 ENSG00000264269.1 DYM-AS1 100129878 DYM antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37046] lncRNA
ENSG00000111981 24.595593 1.169556 0.3652794 3.201811 0.0013657 0.0080078 ENSG00000111981.5 Q9BZM6 ULBP1 ULBP1 80329 UL16 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:14893] protein_coding
ENSG00000171711 82.018488 1.040440 0.3270570 3.181219 0.0014666 0.0085059 ENSG00000171711.3 O15263 DEFB4A DEFB4A 124906748 defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] protein_coding
ENSG00000054179 26.717166 1.051286 0.3311273 3.174868 0.0014990 0.0086743 ENSG00000054179.12 Q9Y5L3 ENTPD2 ENTPD2 954 ectonucleoside triphosphate diphosphohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3364] protein_coding
ENSG00000170356 30.168817 1.076983 0.3395519 3.171777 0.0015151 0.0087585 ENSG00000170356.10 OR2A20P 401428 olfactory receptor family 2 subfamily A member 20 pseudogene [Source:HGNC Symbol;Acc:HGNC:15413] transcribed_unprocessed_pseudogene
ENSG00000171357 19.211400 1.340838 0.4230257 3.169638 0.0015263 0.0088145 ENSG00000171357.6 Q96LR2 LURAP1 LURAP1 541468 leucine rich adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:32327] protein_coding
ENSG00000101342 12.546419 1.538386 0.4892390 3.144448 0.0016640 0.0095130 ENSG00000101342.10 A0PJX2 TLDC2 TLDC2 140711 TBC/LysM-associated domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16112] protein_coding
ENSG00000274114 16.515631 1.361216 0.4331663 3.142480 0.0016752 0.0095710 ENSG00000274114.3 ALOX15P1 NA arachidonate 15-lipoxygenase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13742] transcribed_unprocessed_pseudogene
ENSG00000187513 6.238613 2.331338 0.7534764 3.094109 0.0019741 0.0110205 ENSG00000187513.9 P35212 GJA4 GJA4 2701 gap junction protein alpha 4 [Source:HGNC Symbol;Acc:HGNC:4278] protein_coding
ENSG00000109099 9.779680 2.196132 0.7104239 3.091297 0.0019928 0.0111042 ENSG00000109099.16 J3KT36 PMP22 PMP22 5376 peripheral myelin protein 22 [Source:HGNC Symbol;Acc:HGNC:9118] protein_coding
ENSG00000139292 8.565426 2.206278 0.7193230 3.067159 0.0021610 0.0118871 ENSG00000139292.13 O75473 LGR5 LGR5 8549 leucine rich repeat containing G protein-coupled receptor 5 [Source:HGNC Symbol;Acc:HGNC:4504] protein_coding
ENSG00000233292 26.622607 1.190828 0.3889561 3.061599 0.0022016 0.0120839 ENSG00000233292.1 NA novel zinc finger pseudogene processed_pseudogene
ENSG00000259924 15.945556 1.623864 0.5364454 3.027082 0.0024693 0.0133283 ENSG00000259924.1 NA DnaJ (Hsp40) homolog, subfamily B, member 14 pseudogene processed_pseudogene
ENSG00000183378 15.701056 1.531427 0.5087738 3.010036 0.0026122 0.0139838 ENSG00000183378.13 A0A087X1V8 OVCH2 OVCH2 341277 ovochymase 2 [Source:HGNC Symbol;Acc:HGNC:29970] protein_coding
ENSG00000270127 18.743497 1.213360 0.4036437 3.006018 0.0026469 0.0141312 ENSG00000270127.2 NA novel transcript lncRNA
ENSG00000185303 6.381847 2.452872 0.8161040 3.005587 0.0026507 0.0141469 ENSG00000185303.17 R4GMN3 SFTPA2 SFTPA2 729238 surfactant protein A2 [Source:HGNC Symbol;Acc:HGNC:10799] protein_coding
ENSG00000251194 12.840119 1.475169 0.4931992 2.991021 0.0027805 0.0147500 ENSG00000251194.2 NA novel transcript lncRNA
ENSG00000205057 6.403499 2.904244 0.9902823 2.932744 0.0033598 0.0172612 ENSG00000205057.6 CLLU1-AS1 574016 CLLU1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:24070] lncRNA
ENSG00000206828 26.864395 1.026243 0.3502132 2.930338 0.0033859 0.0173705 ENSG00000206828.1 RNVU1-30 124904627 RNA, variant U1 small nuclear 30 [Source:HGNC Symbol;Acc:HGNC:54434] snRNA
ENSG00000173406 16.383338 1.225758 0.4185495 2.928584 0.0034051 0.0174582 ENSG00000173406.16 O75553 DAB1 DAB1 1600 DAB adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:2661] protein_coding
ENSG00000182334 7.368947 2.246306 0.7670652 2.928443 0.0034066 0.0174610 ENSG00000182334.3 Q8WZ94 OR5P3 OR5P3 120066 olfactory receptor family 5 subfamily P member 3 [Source:HGNC Symbol;Acc:HGNC:14784] protein_coding
ENSG00000123685 17.467316 1.351109 0.4681882 2.885824 0.0039039 0.0196773 ENSG00000123685.9 Q9NR55 BATF3 BATF3 55509 basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915] protein_coding
ENSG00000236700 7.137169 2.074835 0.7202558 2.880692 0.0039680 0.0199376 ENSG00000236700.8 LINC01010 NA long intergenic non-protein coding RNA 1010 [Source:HGNC Symbol;Acc:HGNC:48978] lncRNA
ENSG00000222182 19.288060 1.455316 0.5073379 2.868534 0.0041238 0.0205909 ENSG00000222182.1 RNA5SP156 NA RNA, 5S ribosomal pseudogene 156 [Source:HGNC Symbol;Acc:HGNC:43056] rRNA_pseudogene
ENSG00000144681 25.720244 1.035162 0.3636162 2.846854 0.0044154 0.0218790 ENSG00000144681.11 Q99469 STAC STAC 6769 SH3 and cysteine rich domain [Source:HGNC Symbol;Acc:HGNC:11353] protein_coding
ENSG00000088538 24.190015 1.006025 0.3580317 2.809878 0.0049560 0.0241166 ENSG00000088538.13 Q8IZD9 DOCK3 DOCK3 1795 dedicator of cytokinesis 3 [Source:HGNC Symbol;Acc:HGNC:2989] protein_coding
ENSG00000228477 16.351264 1.395738 0.5035995 2.771524 0.0055795 0.0266035 ENSG00000228477.1 NA ribosomal protein S2 (RPS2) pseudogene processed_pseudogene
ENSG00000049249 24.422051 1.252049 0.4535411 2.760607 0.0057694 0.0273189 ENSG00000049249.10 Q07011 TNFRSF9 TNFRSF9 3604 TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] protein_coding
ENSG00000122877 10.746203 1.513736 0.5492565 2.755973 0.0058518 0.0276123 ENSG00000122877.18 A0A8I5KYI5 EGR2 EGR2 1959 early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] protein_coding
ENSG00000277610 22.993833 1.075311 0.3913490 2.747703 0.0060014 0.0281448 ENSG00000277610.1 RNVU1-4 101954268 RNA, variant U1 small nuclear 4 [Source:HGNC Symbol;Acc:HGNC:48312] snRNA
ENSG00000270343 8.088845 1.822070 0.6676750 2.728977 0.0063531 0.0295342 ENSG00000270343.1 UNGP3 NA uracil-DNA glycosylase pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:20036] processed_pseudogene
ENSG00000160200 7.678611 2.107422 0.7747746 2.720046 0.0065273 0.0302321 ENSG00000160200.18 P35520 CBS CBS 102724560 cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] protein_coding
ENSG00000187955 6.966131 1.841265 0.6772966 2.718551 0.0065569 0.0303451 ENSG00000187955.13 Q05707 COL14A1 COL14A1 7373 collagen type XIV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2191] protein_coding
ENSG00000250328 19.443694 1.078197 0.3989566 2.702541 0.0068812 0.0315881 ENSG00000250328.7 MGC32805 153163 uncharacterized LOC153163 [Source:NCBI gene (formerly Entrezgene);Acc:153163] lncRNA
ENSG00000081985 7.497021 1.823246 0.6754994 2.699108 0.0069526 0.0318911 ENSG00000081985.14 A0A8Q3SIS8 IL12RB2 IL12RB2 3595 interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] protein_coding
ENSG00000115468 10.180969 1.486897 0.5522469 2.692450 0.0070929 0.0323745 ENSG00000115468.13 Q9BUP0 EFHD1 EFHD1 80303 EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] protein_coding
ENSG00000140323 18.477054 1.165680 0.4336484 2.688076 0.0071865 0.0327084 ENSG00000140323.6 A7MBM2 DISP2 DISP2 85455 dispatched RND transporter family member 2 [Source:HGNC Symbol;Acc:HGNC:19712] protein_coding
ENSG00000169562 16.973382 1.061241 0.3972288 2.671612 0.0075488 0.0340576 ENSG00000169562.13 P08034 GJB1 GJB1 2705 gap junction protein beta 1 [Source:HGNC Symbol;Acc:HGNC:4283] protein_coding
ENSG00000151692 16.275979 1.147651 0.4297648 2.670418 0.0075757 0.0341528 ENSG00000151692.15 P50876 RNF144A RNF144A 9781 ring finger protein 144A [Source:HGNC Symbol;Acc:HGNC:20457] protein_coding
ENSG00000070669 20.881688 1.036031 0.3893059 2.661226 0.0077857 0.0349382 ENSG00000070669.17 F8WEJ5 ASNS ASNS 440 asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:HGNC:753] protein_coding
ENSG00000160447 15.409973 1.220421 0.4625176 2.638647 0.0083238 0.0369289 ENSG00000160447.7 Q6P5Z2 PKN3 PKN3 29941 protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:17999] protein_coding
ENSG00000101210 22.285947 1.056417 0.4009207 2.634977 0.0084143 0.0371713 ENSG00000101210.14 Q05639 EEF1A2 EEF1A2 1917 eukaryotic translation elongation factor 1 alpha 2 [Source:HGNC Symbol;Acc:HGNC:3192] protein_coding
ENSG00000272574 13.137581 1.457019 0.5560128 2.620477 0.0087807 0.0384997 ENSG00000272574.1 NA novel transcript, sense intronic to UAP1 lncRNA
ENSG00000287642 15.176610 1.154661 0.4422393 2.610942 0.0090293 0.0393861 ENSG00000287642.3 NA novel transcript, antisense to FHDC1 lncRNA
ENSG00000243477 21.981962 1.006076 0.3858000 2.607766 0.0091135 0.0396920 ENSG00000243477.6 C9J451 NAA80 NAA80 24142 N-alpha-acetyltransferase 80, NatH catalytic subunit [Source:HGNC Symbol;Acc:HGNC:30252] protein_coding
ENSG00000129009 9.650675 1.457406 0.5599864 2.602574 0.0092527 0.0401095 ENSG00000129009.13 H0YL90 ISLR ISLR 3671 immunoglobulin superfamily containing leucine rich repeat [Source:HGNC Symbol;Acc:HGNC:6133] protein_coding
ENSG00000133116 17.273430 1.157660 0.4456110 2.597916 0.0093791 0.0405178 ENSG00000133116.8 Q9UEF7 KL KL 9365 klotho [Source:HGNC Symbol;Acc:HGNC:6344] protein_coding
ENSG00000286811 8.339413 1.810434 0.7002139 2.585545 0.0097225 0.0417857 ENSG00000286811.1 NA novel transcript lncRNA
ENSG00000120729 7.102546 1.662029 0.6454255 2.575091 0.0100214 0.0428383 ENSG00000120729.10 B4DT68 MYOT MYOT 9499 myotilin [Source:HGNC Symbol;Acc:HGNC:12399] protein_coding
ENSG00000183734 13.820569 1.156336 0.4493418 2.573400 0.0100705 0.0429975 ENSG00000183734.5 Q99929 ASCL2 ASCL2 430 achaete-scute family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:739] protein_coding
ENSG00000164638 10.458801 1.354734 0.5286978 2.562398 0.0103952 0.0440845 ENSG00000164638.11 C9IYM7 SLC29A4 SLC29A4 222962 solute carrier family 29 member 4 [Source:HGNC Symbol;Acc:HGNC:23097] protein_coding
ENSG00000125355 16.264411 1.076533 0.4214659 2.554258 0.0106414 0.0450200 ENSG00000125355.16 Q5JRV8 TMEM255A TMEM255A 55026 transmembrane protein 255A [Source:HGNC Symbol;Acc:HGNC:26086] protein_coding
ENSG00000065675 17.283015 1.130302 0.4438232 2.546741 0.0108734 0.0458581 ENSG00000065675.16 Q04759 PRKCQ PRKCQ 5588 protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] protein_coding
ENSG00000188573 7.477348 1.821919 0.7231623 2.519378 0.0117562 0.0488667 ENSG00000188573.8 A6NHQ2 FBLL1 FBLL1 345630 fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458] protein_coding

GSEA analysis (logFc)

GOBP

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 258 0.5158158 1.868329 0.0000014 0.0031036 0.0028865 1295 FGL2/SH2D1B/SOCS1/EMILIN2/RASGRP1/CD274/SERPINB4/CD36/PTPN22/TLR4/HCK/PPARG/ARRB2/RAET1G/ZBP1/CD55/IFI35/CARD9/APPL2/UFD1/RAET1E/GBP5/SPINK5/NOD2/ARG2/SYT11/ADAM8/SEC14L1/NECTIN2/DDX60/TYRO3/KLK7/RNF125/PVR/APOE/SIRT2/FADD/PRKCA/MICA/BMP6/IL4I1/HEXIM1
GOBP_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS 457 0.4607031 1.762532 0.0000009 0.0031036 0.0028865 2373 NOS2/CISH/SOCS1/ALOX15/SLC5A8/PNPLA3/MFSD2A/P2RY1/ELOVL5/GPER1/HAAO/GARS1/MVD/SERAC1/ADCY7/HRH1/TKT/ACSS2/NOS1/NNMT/ELOVL7/ABHD4/FDPS/HMGCS1/LCAT/ME1/INPP5J/FADS1/PLA2G4A/CKMT1A/ADSS2/G6PD/LPCAT4/ELOVL6/CKMT1B/SERINC5/PTDSS1/ACLY/SNCA/MBOAT1/SAMD8/ACOT7/ANTKMT/DGKQ/PIGH/GPAT3/ELOVL1/CWH43/ATP5F1D/DGKA/SOCS2/ELOVL4/IDH1/VPS9D1/CKB/LPIN1/PMVK/DCK/HSD17B12/P2RY6/FAR1/LIPH/IDI1/ATP5MC3/PLD2/ATP5F1B/PDHA1/ATP5MC1/PIK3C2B/SGMS1/PANK3/SLC25A1/TAFAZZIN/ACP6/ALDOA/DOLPP1/UPRT/PIP4K2A/DHDDS/NAPRT/TPK1/MVK/SLC25A16/ADGRF5/INPPL1/DGUOK/SLC26A2/PTPMT1/ACSL1/CPS1/AKR1A1/PIGS/PANK4/SLC25A13/TTC7B/DGKD/MOCS1/NMNAT1/PDHX/DOLK/PGAP4/PIP5K1A/IPPK/NADK/ATP5PO/CHP1/TMEM150A/ENO1/PLAAT3/PDXK/FLCN/LPCAT3/PDK1/ACSL3/GPAT4/GCH1/PARP9/PIGZ/DCTD/ISYNA1/ATP5PF
GOBP_ATTACHMENT_OF_MITOTIC_SPINDLE_MICROTUBULES_TO_KINETOCHORE 13 -0.8501069 -2.021198 0.0000554 0.0385845 0.0358857 898 CDT1/NUF2/CENPE/NDC80/KIF2C
GOBP_STEROL_BIOSYNTHETIC_PROCESS 52 0.6777685 2.004416 0.0000765 0.0385845 0.0358857 2362 CH25H/CYP51A1/LSS/MVD/EBP/INSIG1/DHCR7/FDPS/HMGCS1/HMGCR/MSMO1/G6PD/SREBF1/ACLY/APOE/PMVK/FDFT1/IDI1/NSDHL/SC5D/CYB5R3/MBTPS1/MVK/HSD17B7/SQLE/ABCG1/ERG28/TM7SF2/LPCAT3/CYB5R2
GOBP_GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS 60 0.6533448 1.973875 0.0001416 0.0385845 0.0358857 1366 NOS2/TAT/SLC39A8/PHGDH/GOT1/ASNS/SLC7A11/NOS1/PYCR1/ARG2/NAGS/ADHFE1/DDAH2/PRODH/GLS2
GOBP_CHRONIC_INFLAMMATORY_RESPONSE 11 -0.8696239 -1.966654 0.0000836 0.0385845 0.0358857 721 ADORA2B/THBS1/TNF/VNN1/S100A9/VCAM1/S100A8
GOBP_SECONDARY_ALCOHOL_METABOLIC_PROCESS 108 0.5932020 1.915776 0.0000310 0.0385845 0.0358857 1944 CH25H/CYP51A1/LSS/MVD/EBP/PCSK9/INSIG1/NFE2L1/DHCR7/FDPS/HMGCS1/LCAT/HMGCR/CYP2C9/SCARB1/MSMO1/G6PD/NPC1/CYP27B1/SREBF1/ACLY/LDLR/ACO2/ABCA5/SULT2B1/APOE/DGKQ/GBA2/IDH1/PMVK/FDFT1/IDI1/NSDHL/CYP2R1/SC5D/CYB5R3/OSBPL1A/SREBF2/MBTPS1/CYP46A1/MVK/HSD17B7/APOL2/SQLE/ABCG1/SMPD1
GOBP_ALCOHOL_BIOSYNTHETIC_PROCESS 105 0.5766859 1.859719 0.0001380 0.0385845 0.0358857 2567 P2RY1/CYP51A1/GPER1/LSS/MVD/PCK2/EBP/HRH1/GOT1/INSIG1/DHCR7/FDPS/HMGCS1/HMGCR/MSMO1/G6PD/CYP27B1/SREBF1/ACLY/SNCA/PTS/APOE/DGKQ/PMVK/BMP6/P2RY6/FDFT1/IDI1/NSDHL/CYP2R1/SC5D/CYB5R3/DHDDS/MBTPS1/ACER3/MVK/HSD17B7/ABCG1/IPPK/ACER2/TM7SF2/LPCAT3/GCH1/ISYNA1/CLCN2/PCBD1
GOBP_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION 94 -0.5108650 -1.822729 0.0001098 0.0385845 0.0358857 2543 TRIP13/ATM/RGCC/CCNB1/BUB1/NEK2/FBXO5/MTBP/EDN1/PLK1/EGF/KIF20B/CDCA2/BMP4/TTK/CHEK1/DLGAP5/MAD2L1/DUSP1/ANAPC4/CDT1/MKI67/CENPF/CDC25C/INSR/IGF2/BUB1B/TNF/NDC80/EPGN/IL1B/PDGFB
GOBP_REGULATION_OF_REPRODUCTIVE_PROCESS 109 -0.4885420 -1.792841 0.0001533 0.0385845 0.0358857 2037 FBXO5/WNT5A/ESR1/CCDC87/PLB1/GDF9/LIF/CITED2/INHBB/HORMAD1/CDC20/NOX5/BMP4/CACNA1H/EAF2/CFAP206/TTK/UMODL1/NPR2/DUSP1/ASPM/PLA2G10/PDE5A/CDC25C/INSR/OVGP1/SHH/GJA1/OXTR/EPPIN/INHBA/ARHGDIB/DEFB1/PLAT/AR/CNTD1
GOBP_NEGATIVE_REGULATION_OF_NEURON_DEATH 155 0.5185939 1.764463 0.0001127 0.0385845 0.0358857 1484 NTRK1/GDNF/PLA2G3/BDNF/NTRK2/ARRB2/FZD1/SLC7A11/AARS1/CD200R1/GRIK2/BCL2/HIF1A/ADAM8/KRAS/FOXQ1/CNTF/GPNMB/ATF4/SNCA/AP2B1/SORL1/IKBKG/TYRO3/NR4A3/APOE/AXL/NRBP2/ZPR1/WFS1/GPI/UNC5B/IL27RA
GOBP_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES 125 -0.4599310 -1.736424 0.0001692 0.0385845 0.0358857 2444 NEXN/CELSR1/PCDHB13/PCDHGA9/ROBO3/PCDHAC2/PCDHGB2/CEACAM6/FAT2/PCDHB11/PTPRM/FAT1/PCDHGA6/PCDHGC4/PCDHGA11/PCDHB7/PCDHGB1/PCDHGC3/ITGB1/AMIGO2/CDH19/PCDHGB4/PCDHB4/MPZL2/PCDHGA8/PCDHA6/CDHR2/PCDHA11/CDH2/PCDHGA4/NECTIN1/DSC2/CDHR3/PCDHGA12/PCDHB9/PCDHB14/PCDHGA5/DSC3/L1CAM/KIRREL3/CDH23/PCDHA10/ROBO2/PCDHGB3/PTPRR/RET/PCDHGC5/CLSTN2/PCDHA5/PCDH9/DCHS2/PCDHB1/PCDHB12/PTPRT/PCDHA9/DSCAML1/PCDHA12/PCDH18
GOBP_CELLULAR_RESPONSE_TO_PEPTIDE 278 0.4677690 1.708260 0.0000649 0.0385845 0.0358857 1553 NTRK1/ANO1/SOCS1/CA2/EDNRA/KLF2/CD36/PTPN22/TLR4/PNPLA3/MAP1B/TRIB3/GJB2/PPARG/GPER1/KL/PCK2/PRKCQ/GOT1/MARS1/PTPRE/PCSK9/INSIG1/RAB15/APPL2/FBP1/GPT/CPEB2/NR4A1/NOD2/KLF11/SREBF1/FBN1/SORL1/ZBTB7B/NR4A3/GRB10/RAB31/CCND3/EEF2K/SOCS2/TBC1D4/KAT2B/SLC27A4/CYP1B1/LPIN1/CDC6/CAV2/ABCC1/DENND4C/MYO1C/EPRS1/SLC29A2/SLC9A1/PIP4K2A/ZDHHC7
GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 221 0.4781555 1.702866 0.0001481 0.0385845 0.0358857 1403 NOS2/FGL2/SH2D1B/PLA2G3/RASGRP1/SERPINB4/CD36/PTPN22/TLR4/ARRB2/RAET1G/GATA3/TNFSF13/CD55/APPL2/FZD5/RAET1E/HK1/SPINK5/GAB2/NOD2/TRPM4/ANXA1/NECTIN2/DDX60/ZBTB7B/NR4A3/KLK7/COLEC10/PVR/IL4R/CD81/FADD/IL18R1/MICA/CD47/IL20RB/IL4I1/RIPK3/AZGP1/CD40/GPI/SERPINB9
GOBP_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY 214 0.4781421 1.695589 0.0001654 0.0385845 0.0358857 2384 CCL26/NTRK1/FZD10/RASGRP1/SFRP1/RTN4R/ARHGEF5/ASAP3/DOCK11/RGS16/RIC1/RAP1GAP/GRHL3/NEDD9/TBC1D4/SLC27A4/TBC1D10A/NGEF/TBC1D14/ARHGAP27/CCL14/ADAP2/TBC1D22A/SH3BP1/CAV2/GARNL3/CD40/EVI5L/RAPGEF4/SIPA1L2/SNX9/CHN1/GMIP/RAPGEFL1/RABGAP1/NDEL1/TBC1D16/SIPA1L1/RGP1/TBC1D9/PIP5K1A/TBC1D20/RASGRF2/BIN1/DOCK9/ARHGAP25/ABR/FLCN/RAP1A/TAX1BP3/ARHGEF10/RALGPS1/ADPRH/RAPGEF6
GOBP_ANION_TRANSPORT 330 0.4467745 1.659277 0.0001033 0.0385845 0.0358857 1695 NOS2/ANO1/PLA2G3/CA2/SLC5A5/SLC26A4/SLC9A3/SLC24A3/CD36/SLC39A8/NTRK2/SLC16A9/SLC5A1/ACE/TTYH2/SLC26A9/SLC5A8/SLC2A6/LRRC8D/MFSD2A/SLC16A14/TCAF2/SLC6A14/SLC25A25/SLC12A2/SLC7A11/SLCO1B3/ATP8B1/TG/LRRC8B/SLC1A5/SLC36A1/RGS2/SLC26A11/PLA2G4A/CLIC3/SFXN5/ANO8/SLCO4C1/SLCO4A1/SLC7A1/ANO7/ANXA1/SLC4A9/SERINC5/SLC26A6/ATF4/LRRC8A/SNCA/SLC1A4/WNK4/SLC25A5/SLC3A2/MPC1/SLC16A7/SLC4A3/CPTP/SLC27A4/SLC25A3/SLC2A10/P2RY6/CD47/SLCO3A1/PRAF2/SLC16A4/ABCC1/CLIC4/SLC17A5/ANO10/PACC1/SLC25A1/GABRA3/SLC9A1/SLC25A22/SLC38A7/SLC6A9/SLC52A2/SLC35B4/SLC35D1/SLC66A1/SLC7A5/SLC9A9
GOBP_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT 331 0.4379673 1.625082 0.0001536 0.0385845 0.0358857 1775 NTRK1/PTPRO/PLA2G3/SDC2/PRKD1/BDNF/NTRK2/SFRP1/PMP22/EPHA3/CRMP1/RTN4R/KLF4/MFSD2A/MAP1B/ALKAL1/DAB1/GATA3/EPHB3/FZD1/ZNF365/TNIK/CNTN1/NTNG1/SLIT1/CNR1/AMIGO1/CAMK1D/INPP5J/RGS2/PTPRD/RUFY3/TWF2/CNTF/SLIT2/SEMA6A/TENM3/MBOAT1/VEGFA/PPP2R5B/CCDC88A/FKBP1B/APOE/RELN/CHODL/EEF2K/ACAP3/SEMA3B/NGEF/SEMA4C/NRCAM/CDK5R1/KREMEN1/PTPRG/NSMF/SEMA4A/ROR1/CHN1/TRPV4/RAB11A/DBN1/BAG5/NDEL1/DGUOK/STK25/PTK6/SIPA1L1/PLXNA3/SEMA3D/KATNB1
GOBP_REGULATION_OF_HORMONE_LEVELS 329 0.4345424 1.613692 0.0001686 0.0385845 0.0358857 1492 NOS2/ANO1/DPP4/PLA2G3/C1QTNF1/SLC5A5/TRPV6/SLC9B2/PCSK6/SFRP1/ACE/ADH1C/LRAT/CYP2S1/STC2/P2RY1/PPARG/DUOX2/GPER1/DUOXA1/GATA3/CPT1A/CYP26A1/PCK2/FOXD1/GPR27/GCNT4/FAM3B/DUOX1/TG/CNR1/DHCR7/DHRS7/CYP2C9/CYP2C18/HIF1A/TRPM4/MYRIP/VSNL1/SLCO4A1/RDH11/ATP1A1/ANXA1/EGR1/CYP27B1/SREBF1/LRRC8A/LTBP4/EIPR1/DUOXA2/CPQ/FKBP1B/DGKQ/DHRS11/DOC2B/CYP1B1/BACE2/SDR16C5/BMP6/HSD17B12/RAB11FIP1/ALDH1A3/IL4I1/RETSAT/RAPGEF4/SELENOM/HMGN3/DISP1/TRPV4/NIBAN2/RDH13
GOBP_RESPONSE_TO_WOUNDING 413 0.4238536 1.607636 0.0001161 0.0385845 0.0358857 1251 NTRK1/CCN4/VWF/EMILIN2/ADRA2C/C1QTNF1/ALOX15/EDNRA/SELP/SERPINB2/CD36/PROCR/TLR4/SMOC2/RTN4R/CD44/KLF4/MAP1B/P2RY1/PPARG/PHLDB2/THBD/DUOX2/TNC/CLASP1/EPPK1/HBEGF/PRKCQ/PEAR1/FAP/SOX2/ENTPD2/SLC12A2/SLC7A11/CD9/DUOX1/GRHL3/F3/SPRR3/BCL2/YAP1/PLA2G4A/HIF1A/TSPAN8/SYT11/SCARB1/CNTF/MPL/ANXA1/KRT6A/RAB3A/VEGFA/TYRO3/HPSE/FKBP1B/ID3/LOX/APOE/DGKQ/DGKA/PRKCA/ZFP36/VCL/AXL/ST3GAL4/MIA3/NOTCH4/CADM4
GOBP_BEHAVIOR 376 0.4258180 1.601860 0.0001058 0.0385845 0.0358857 1086 NTRK1/SLC18A2/CLDN5/GDNF/DPP4/LYPD1/MME/BDNF/NTRK2/SGK1/HTR1D/BRINP1/ACE/AFF2/ADM2/HOMER2/MFSD2A/EGR2/P2RY1/ARRB2/DAB1/FGF12/CPT1A/HRH1/DRD1/CNTN1/SLC7A11/GCNT4/CNR1/UCHL1/FOXO6/HMGCR/GRIK2/CIART/BCL2/HIF1A/SYT11/KRAS/MAPK8IP2/NPC1/GJB4/EGR1/LPAR5/MRAP2/ITPR3/SNCA/LDLR/NR4A3/APOE/RELN/MMP17/FADD
GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS 104 0.5764646 1.858877 0.0001979 0.0389299 0.0362070 1484 NTRK1/GDNF/PLA2G3/BDNF/NTRK2/ARRB2/AARS1/GRIK2/BCL2/HIF1A/ADAM8/KRAS/FOXQ1/CNTF/SNCA/TYRO3/APOE/AXL/NRBP2/ZPR1/WFS1/GPI/UNC5B/IL27RA
GOBP_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT 113 0.5577930 1.818429 0.0001999 0.0389299 0.0362070 1037 NTRK1/PLA2G3/PRKD1/BDNF/NTRK2/EPHA3/ALKAL1/FZD1/CNTN1/CNR1/AMIGO1/CAMK1D/RGS2/TWF2/CNTF/TENM3/PPP2R5B/FKBP1B/APOE/RELN/EEF2K
GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 120 0.5505350 1.802496 0.0002029 0.0389299 0.0362070 1295 SH2D1B/EMILIN2/RASGRP1/CD274/TLR4/HCK/RAET1G/ZBP1/IFI35/CARD9/RAET1E/GBP5/NOD2/ADAM8/NECTIN2/DDX60/KLK7/PVR/FADD/PRKCA/BMP6/HEXIM1
GOBP_REGULATION_OF_NUCLEAR_DIVISION 109 -0.4835062 -1.774361 0.0002049 0.0389299 0.0362070 2543 TRIP13/ATM/RGCC/CCNB1/BUB1/NEK2/FBXO5/WNT5A/MTBP/EDN1/PLK1/LIF/EGF/KIF20B/HORMAD1/CDC20/CDCA2/BMP4/TTK/CHEK1/DLGAP5/MAD2L1/DUSP1/ANAPC4/CDT1/MKI67/CENPF/CDC25C/INSR/IGF2/BUB1B/TNF/NDC80/EPGN/IL1B/PDGFB
GOBP_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS 50 0.6735063 1.973619 0.0002238 0.0400627 0.0372605 1006 NTRK1/DPP4/LYPD1/GJA4/BRINP1/DRD1/NOS1/GRIK2/BCL2/MAPK8IP2/LPAR5/APOE/RELN
GOBP_RESPONSE_TO_PEPTIDE 370 0.4252330 1.601866 0.0002284 0.0400627 0.0372605 1815 NTRK1/ANO1/SOCS1/CA2/EDNRA/KLF2/CD36/PTPN22/TLR4/PNPLA3/EGR2/MAP1B/TRIB3/STC2/GJB2/PPARG/GPER1/KL/PCK2/PRKCQ/GOT1/ZBED3/MARS1/PTPRE/PCSK9/INSIG1/CARD9/RAB15/APPL2/FBP1/TRIM16/GPT/CPEB2/NR4A1/NOD2/KLF11/ANXA1/EGR1/SESN2/BTG1/SREBF1/FBN1/SORL1/ZBTB7B/LTA4H/NR4A3/GRB10/RAB31/CCND3/EEF2K/SOCS2/TBC1D4/KAT2B/CYC1/SLC27A4/CYP1B1/LPIN1/CDC6/CAV2/ABCC1/DENND4C/MYO1C/EPRS1/TRPV4/SLC29A2/SLC9A1/UPRT/PIP4K2A/ZDHHC7/TIMP4/NDEL1/INPPL1/CACNB1/HADHA/OSBPL8/HSD11B2/PTPN1/CPS1/NFKBIA
GOBP_REGULATION_OF_PROTEIN_POLYMERIZATION 163 0.5046608 1.729649 0.0003004 0.0482536 0.0448785 3113 CCL26/ALOX15/CDC42EP5/HCK/MAP1B/CLASP1/INPP5J/GSN/TWF2/TMSB10/DLG1/ARHGAP40/SLIT2/KANK3/SNCA/MET/GBA2/CDK5R1/ARPC5L/ANKRD53/FLII/SNX9/DBN1/HSPA1A/RAC1/CLIP3/TMOD2/NUMA1/RANGRF/ADD3/HIP1R/GIT1/VDAC2/TPPP/WASHC2C/ARL2/SVIL/SSH1/HSPA1B/BIN1/CAMSAP3/ARPC4/CTTN/FKBP4/RHOA/ARFGEF1/ARPC1B/DBNL/SLAIN1/CKAP5/HAX1/DMTN/KANK1/PAK1/MTOR/DCTN1/ARPC1A/EVL/AKAP9/TBCD/CAPG/EML2
GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE 165 0.4984273 1.717797 0.0003147 0.0482536 0.0448785 1155 SH2D1B/SOCS1/RASGRP1/SERPINB4/PTPN22/TLR4/HCK/PPARG/ARRB2/RAET1G/ZBP1/IFI35/CARD9/APPL2/RAET1E/GBP5/NOD2/ADAM8/NECTIN2/TYRO3/PVR/APOE/FADD/MICA
GOBP_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS 222 0.4604476 1.644657 0.0003101 0.0482536 0.0448785 2092 SOCS1/CA2/EDNRA/PNPLA3/MAP1B/TRIB3/GJB2/PPARG/GPER1/KL/PCK2/PRKCQ/GOT1/MARS1/PTPRE/PCSK9/INSIG1/RAB15/APPL2/FBP1/GPT/CPEB2/NR4A1/SREBF1/FBN1/SORL1/ZBTB7B/NR4A3/GRB10/RAB31/CCND3/EEF2K/SOCS2/TBC1D4/KAT2B/SLC27A4/CYP1B1/LPIN1/CDC6/CAV2/DENND4C/MYO1C/EPRS1/SLC29A2/SLC9A1/PIP4K2A/ZDHHC7/NDEL1/OSBPL8/PTPN1/CPS1/SLC2A8/LPIN2/HDAC9/SELENOS/CAV1
GOBP_WOUND_HEALING 323 0.4273373 1.583786 0.0003175 0.0482536 0.0448785 1251 CCN4/VWF/EMILIN2/ADRA2C/C1QTNF1/ALOX15/SELP/SERPINB2/CD36/PROCR/TLR4/SMOC2/CD44/P2RY1/PPARG/PHLDB2/THBD/DUOX2/CLASP1/EPPK1/HBEGF/PRKCQ/PEAR1/FAP/ENTPD2/SLC12A2/SLC7A11/CD9/DUOX1/GRHL3/F3/SPRR3/YAP1/PLA2G4A/HIF1A/TSPAN8/SYT11/SCARB1/MPL/ANXA1/KRT6A/RAB3A/VEGFA/TYRO3/HPSE/LOX/APOE/DGKQ/DGKA/PRKCA/VCL/AXL/ST3GAL4/MIA3/NOTCH4/CADM4

GOMF

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 151 0.5308814 1.830024 0.0002392 0.0363147 0.0342398 1807 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC9B2/SLC24A3/SLC39A8/SLC16A9/SLC5A1/SLC9B1/SLC26A9/SLC5A8/MFSD2A/SLC16A14/SLC6A14/SLC45A4/SLC12A2/SLC7A11/SLCO1B3/SLC1A5/SLC36A1/SLC5A3/SLC26A11/SLCO4C1/SLCO4A1/SLC4A9/SLC26A6/SLC1A4/SLC25A5/SLC3A2/SLC16A7/SLC4A3/SLC25A3/SLC2A10/SLC35E4/SLCO3A1/SLC15A1/SLC16A4/SLC17A5/SLC25A1/SLC9A1/SLC25A22/SLC6A9/SLC45A3/SLC35D1/SLC7A5/SLC9A9/SLC25A16/SLC28A3/SLC26A2/MCU
GOMF_ACTIVE_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 172 0.5153634 1.804324 0.0002087 0.0363147 0.0342398 2510 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC9B2/ATP12A/SLC24A3/SLC39A8/SLC5A1/SLC9B1/SLC26A9/SLC5A8/ATP6V1C2/MFSD2A/SLC45A4/SLC12A2/SLC7A11/SLCO1B3/SLC36A1/SLC5A3/SLC26A11/SLCO4C1/SLCO4A1/ATP1A1/SLC4A9/ATP7B/SLC26A6/SLC25A5/SLC3A2/SLC16A7/SLC4A3/CYC1/SLC25A3/SLC2A10/ATP1B1/SLCO3A1/SLC15A1/ABCC1/ATP5F1B/SLC17A5/SLC25A1/SLC9A1/ATP6V1E2/SLC25A22/SLC6A9/SLC45A3/SLC9A9/SLC28A3/SLC26A2/COX4I1/UQCRFS1/COX8A/COX5A/ABCC10/SLC22A18/SLC4A11/ATP6V0E2/UQCRC1/SLC38A1/COX7B/COX6B1/SLC10A3/SLC25A11/ATP6V0D1/SLC37A4/CLCN6/LETM1
GOMF_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 205 0.4853043 1.732752 0.0001913 0.0363147 0.0342398 1695 SLC18A2/ANO1/SLC5A5/SLC26A4/SLC9A3/SLC24A3/CD36/SLC39A8/TTYH2/SLC26A9/SLC5A8/SLC2A6/LRRC8D/MFSD2A/SLC6A14/SLC25A25/SLC12A2/SLC7A11/SLCO1B3/LRRC8B/SLC1A5/SLC36A1/SLC26A11/CLIC3/SFXN5/ANO8/SLCO4C1/SLCO4A1/SLC7A1/ANO7/SLC4A9/SERINC5/SLC26A6/LRRC8A/SLC1A4/SLC25A5/SLC3A2/MPC1/SLC16A7/SLC4A3/SLC27A4/SLC2A10/SLCO3A1/ABCC1/CLIC4/ANO10/PACC1/SLC25A1/GABRA3/SLC9A1/SLC25A22/SLC38A7/SLC6A9/SLC52A2/SLC35B4/SLC35D1/SLC66A1/SLC7A5/SLC9A9
GOMF_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 284 0.4551581 1.681447 0.0001626 0.0363147 0.0342398 2510 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC9B2/ATP12A/SLC24A3/SLC39A8/SLC16A9/SLC5A1/SLC9B1/SLC26A9/SLC5A8/ATP6V1C2/MFSD2A/SLC29A4/SLC16A14/SLC6A14/SLC45A4/SLC12A2/SLC7A11/SLCO1B3/SLC1A5/SLC36A1/SLC5A3/ABCA3/SLC26A11/TAP2/SLCO4C1/SLCO4A1/ATP1A1/SLC4A9/ATP7B/SLC26A6/SLC1A4/ABCA5/SLC25A5/NDUFS7/SLC3A2/SLC16A7/SLC4A3/CYC1/SLC25A3/SLC2A10/SLC35E4/ATP1B1/SLCO3A1/SLC15A1/NDUFV1/NDUFS6/SLC16A4/ABCC1/ATP5F1B/SLC17A5/ABCA9/SLC25A1/SLC9A1/ATP6V1E2/SLC25A22/SLC6A9/SLC45A3/SLC35D1/NDUFA6/SLC7A5/SLC9A9/SLC25A16/CYB561D1/SLC28A3/SLC26A2/NDUFS8/COX4I1/MCU/ABCG1/UQCRFS1/COX8A/COX5A/ABCC10/NDUFS3/SLC22A18/NDUFA13/SLC4A11/NDUFB9/SLC16A13/ATP6V0E2/UQCRC1/SLC38A1/COX7B/COX6B1/NDUFV3/SLC10A3/ABCA7/SLC25A11/ATP6V0D1/SLC37A4/CLCN6/NDUFS4/LETM1
GOMF_INORGANIC_MOLECULAR_ENTITY_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 426 0.4189642 1.618593 0.0000911 0.0363147 0.0342398 2484 CALHM4/SLC18A2/ANO1/TRPM6/SLC5A5/TRPV6/CALHM5/KCNJ16/SLC26A4/SLC9A3/SLC9B2/ATP12A/SLC24A3/KCNS3/SLC39A8/CACNB4/SLC5A1/TTYH2/SLC9B1/KCNE3/SLC26A9/SLC5A8/ATP6V1C2/LRRC8D/MFSD2A/KCNMB4/SLC30A4/TMC1/ORAI1/SLC45A4/SLC12A2/CNR1/LRRC8B/SLC36A1/SLC5A3/GRIK2/TMC6/SLC26A11/ATP6V0A2/SCN4B/TRPM4/CLIC3/KCNK6/ANO8/ATP1A1/ANO7/SLC4A9/ATP7B/SLC26A6/NIPA1/MCUB/ITPR3/LRRC8A/TPCN2/SLC1A4/SLC25A5/FKBP1B/SLC3A2/RYR3/STIM2/SLC4A3/ATP5F1D/CYC1/SLC25A3/KCNN3/SLC2A10/NIPAL1/ATP1B1/SLC15A1/ATP5MC3/ABCC1/ATP5F1B/CLIC4/SLC17A5/ATP5MC1/ANO10/PACC1/NNT/CACNB3/HVCN1/NALF2/TRPV4/MCOLN1/GABRA3/SLC39A4/CATSPER3/PKD2/SLC9A1/ATP6V1E2/SLC25A22/SLC6A9/KCNQ5/SLC45A3/SLC39A1/TMEM63C/SLC9A9/CACNB1/SHROOM2/SLC28A3/SLC26A2/COX4I1/MCU/PKD1/UQCRFS1/COX8A/VDAC2/COX5A/ABCC10/SLC22A18/ATP5PO/PDPN/KCNG1/SLC4A11/P2RX4/CCDC51/ATP6V0E2/UQCRC1/HCN4/SLC38A1/ORAI3/KCND3/TMEM120A/CACNA2D4/MFSD5/COX7B/COX6B1/ATP5PF/SLC10A3/MMGT1/SLC25A11/ATP6V0A1/VDAC1/ATP6V0D1/SLC37A4/CLCN2/CACNG8/CLCN6
GOMF_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 385 0.4215592 1.611096 0.0001931 0.0363147 0.0342398 1865 CALHM4/SLC18A2/ANO1/TRPM6/SLC5A5/TRPV6/CALHM5/KCNJ16/SLC9A3/SLC9B2/ATP12A/SLC24A3/KCNS3/SLC39A8/CACNB4/SLC5A1/SLC9B1/KCNE3/SLC5A8/ATP6V1C2/MFSD2A/KCNMB4/SLC29A4/SLC30A4/TMC1/SLC6A14/ORAI1/SLC45A4/SLC12A2/CNR1/SLC1A5/SLC36A1/SLC5A3/GRIK2/ATP6V0A2/SCN4B/TRPM4/KCNK6/ATP1A1/SLC7A1/SLC4A9/SERINC5/ATP7B/NIPA1/ITPR3/TPCN2/SLC1A4/SLC25A5/FKBP1B/SLC3A2/RYR3/STIM2/ATP5F1D/CYC1/SLC25A3/KCNN3/SLC2A10/NIPAL1/ATP1B1/SLC15A1/ATP5MC3/ATP5F1B/SLC17A5/ATP5MC1/ANO10/NNT/CACNB3/HVCN1/NALF2/TRPV4/MCOLN1/SLC39A4/CATSPER3/PKD2/SLC9A1/ATP6V1E2/SLC25A22/SLC38A7/SLC6A9/KCNQ5/SLC45A3/SLC39A1/TMEM63C/SLC66A1/SLC7A5/SLC9A9/CACNB1/SHROOM2/SLC28A3/COX4I1/MCU/PKD1/UQCRFS1/COX8A

Reactome

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 62 -0.5978841 -1.971159 0.0000269 0.0142222 0.0133935 4503 H2BC4/H2AC8/CENPQ/RBBP7/H2BC6/H2AX/H2BC5/H2AJ/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/RBBP4/H4C9/H4C1/CENPI/NPM1/H4C3/H4C5/CENPN/ITGB3BP/H2AC14/H2BC9/H4C6/H2AC4/CENPU/H2BC17/H4C4/KNL1/CENPP/CENPK/H4C11/CENPM/MIS18BP1/MIS18A/H4C13/H4C12/H2BC3/H2BC13/H2BC10/HJURP/CENPW
REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES 61 -0.5947811 -1.955401 0.0000343 0.0142222 0.0133935 4513 H3-3A/H2BC4/H2AC8/H3C6/H2BC6/H2AX/NCAPG2/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/H4C9/H4C1/H3C1/H3C10/H4C3/SMC2/H4C5/H2AC14/SMC4/CCNB1/H2BC9/H4C6/H2AC4/H2BC17/H4C4/PLK1/H3C8/H4C11/H3C7/H4C13/CDK1/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA 61 -0.5932827 -1.950475 0.0000375 0.0142222 0.0133935 4513 H3-3A/H2BC4/H2AC8/H3C6/RBBP7/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/EZH2/H2AC6/RBBP4/EED/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/MTF2/H2AC14/H2BC9/H4C6/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_CHOLESTEROL_BIOSYNTHESIS 24 0.8228980 2.079667 0.0000806 0.0145899 0.0137398 1757 CYP51A1/LSS/MVD/EBP/DHCR7/FDPS/HMGCS1/HMGCR/ACAT2/MSMO1/PMVK/FDFT1/IDI1/NSDHL/SC5D/MVK/HSD17B7/SQLE
REACTOME_DNA_METHYLATION 52 -0.5996267 -1.914176 0.0000890 0.0145899 0.0137398 4513 H3-3A/H2BC4/H2AC8/H3C6/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/H2BC9/H4C6/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3 53 -0.5901700 -1.903186 0.0000897 0.0145899 0.0137398 4513 H3-3A/H2BC4/H2AC8/KDM1A/H3C6/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/H2BC9/H4C6/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3/AR
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES 66 -0.5600100 -1.877083 0.0000615 0.0145899 0.0137398 4551 RPS2/H2AC8/H3C6/RBBP7/H2AX/SMARCA2/ARID2/H2AJ/H3C11/H4C2/SMARCC1/H2AC6/ARID1B/H4C9/JAK2/H4C1/H3C1/H3C10/H4C3/ACTL6A/H4C5/H2AC15/H2AC14/SMARCE1/WDR77/H2AC16/H4C6/H2AC4/SMARCD3/H4C4/H2AC13/H2AC12/H3C8/H4C11/H2AC21/H3C7/H2AC11/H4C13/CCND1/H4C12/H3C12/H3C13/H3C2/H3C3
REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION 64 -0.5616708 -1.860372 0.0001296 0.0165794 0.0156133 4513 H3-3A/H2BC4/H2AC8/H3C6/RBBP7/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/TTF1/H2BC7/H2AC6/RBBP4/H4C9/H4C1/H3C1/H3C10/H4C3/HDAC2/H4C5/H2AC14/H2BC9/CBX3/H4C6/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_MEIOTIC_RECOMBINATION 68 -0.5503583 -1.853258 0.0001310 0.0165794 0.0156133 4513 H3-3A/H2BC4/H2AC8/H3C6/PSMC3IP/H2BC6/RPA1/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/BLM/MRE11/BRCA2/H2BC7/H2AC6/H4C9/H4C1/H3C1/H3C10/H4C3/NBN/H4C5/H2AC14/ATM/RBBP8/RPA3/H2BC9/H4C6/H2AC4/H2BC17/H4C4/BRCA1/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_HDACS_DEACETYLATE_HISTONES 80 -0.5260564 -1.829196 0.0001928 0.0219549 0.0206756 4503 H2BC4/H2AC8/KDM1A/H3C6/RBBP7/H2BC6/ARID4A/H2BC5/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/RBBP4/H2BC18/H4C9/H4C1/H3C1/H3C10/SAP30/H4C3/HDAC8/HDAC2/H4C5/H2AC15/H2AC14/H2AC16/H2BC9/H4C6/TBL1XR1/H2AC4/H2BC17/H4C4/H2AC13/H2AC12/H3C8/H4C11/H2AC21/H3C7/H2AC11/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_SIGNALING_BY_NTRKS 117 0.5677458 1.881234 0.0002208 0.0223787 0.0210747 3377 NTRK1/PTPRO/PCSK6/BDNF/NTRK2/SGK1/EGR2/MAPKAPK3/DOCK3/F3/KRAS/EGR1/AP2B1/DUSP7/ID3/AP2M1/MAPK12/FOS/AP2A2/CDK5R1/DUSP3/FOSB/RAC1/PCSK5/ELK1/MAPK11/RAP1A/RHOA/NTF4/MAPKAPK2/NRAS/JUND/HRAS/CRK/MAPK3/VRK3/TRIB1/MAPK13/MAPK1/MAPK7/FYN/FURIN/SRC/RAPGEF1/PTPN11/PPP2R5D/KIDINS220
REACTOME_STIMULI_SENSING_CHANNELS 72 0.6027155 1.868450 0.0002358 0.0223787 0.0210747 1457 ANO1/CASQ2/TRPM6/TRPV6/SLC9B2/SGK1/TTYH2/SLC9B1/STOM/TRPM4/ANO8/ANO7/TPCN2/WNK4/FKBP1B/RYR3/RIPK3/ANO10/TRPV4/MCOLN1
REACTOME_ION_CHANNEL_TRANSPORT 124 0.5467301 1.828394 0.0002977 0.0260808 0.0245611 1557 ANO1/CASQ2/TRPM6/TRPV6/SLC9B2/ATP12A/SGK1/TTYH2/SLC9B1/ATP6V1C2/STOM/ATP8B1/ATP6V0A2/TRPM4/ANO8/ATP1A1/ANO7/ATP7B/TPCN2/WNK4/FKBP1B/RYR3/ATP1B1/ATP11A/RIPK3/ANO10/TRPV4/MCOLN1/ATP6V1E2/CAMK2D
REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH 89 -0.4945424 -1.755491 0.0003460 0.0281469 0.0265068 4591 POLA1/H3-3A/H2BC4/H2AC8/H3C6/CDK5/RBBP7/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/EZH2/H2AC6/RBBP4/EED/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/CAST/H2BC9/H4C6/CDC25A/H2AC4/H2BC17/H4C4/FOXO3/H3C8/H4C11/H3C7/H4C13/POLA2/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3/CDC25C/LMNB1/CAPNS2
REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX 78 -0.5012916 -1.733217 0.0003838 0.0291416 0.0274436 4513 H3-3A/H2BC4/H2AC8/H3C6/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/H2BC9/H4C6/BCL9/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/AXIN2/PYGO1/H4C12/H3C12/H2BC3/H3C13/H2BC13/TCF7/LEF1/H3C2/H2BC10/H3C3/RUNX3
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS 71 -0.5250209 -1.764785 0.0004444 0.0316360 0.0297926 4513 H3-3A/H2BC4/H2AC8/H3C6/H2BC6/H2AX/STAT3/H2BC5/H2AJ/CEBPB/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/H4C9/CEBPA/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/H2BC9/DEK/RXRA/H4C6/H2AC4/H2BC17/H4C4/E2F1/TFDP2/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/LEF1/H3C2/H2BC10/H3C3/MYB
REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION 56 -0.5498277 -1.788612 0.0004968 0.0332839 0.0313445 4513 H3-3A/H2BC4/H2AC8/H3C6/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/H2BC9/H4C6/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF 55 0.6344847 1.855576 0.0005359 0.0339115 0.0319355 2217 CYP51A1/LSS/MVD/INSIG1/DHCR7/FDPS/HMGCS1/HMGCR/SCD/ELOVL6/SREBF1/PMVK/FDFT1/IDI1/SC5D/FASN/HELZ2/SREBF2/MBTPS1/MVK/SQLE/SEC23A/TM7SF2
REACTOME_MEIOSIS 92 -0.4756342 -1.696361 0.0006379 0.0382425 0.0360142 4513 H3-3A/H2BC4/H2AC8/H3C6/PSMC3IP/H2BC6/RPA1/H2AX/H2BC5/H2AJ/H3C11/STAG2/H4C2/H2BC8/H2BC15/H2BC12/BLM/MRE11/ATR/BRCA2/H2BC7/H2AC6/H4C9/H4C1/SYNE1/H3C1/H3C10/H4C3/NBN/HSPA2/H4C5/H2AC14/ATM/RBBP8/RPA3/H2BC9/REC8/H4C6/H2AC4/H2BC17/H4C4/BRCA1/H3C8/H4C11/H3C7/H4C13/STAG3/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3/LMNB1
REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION 56 -0.5430690 -1.766626 0.0006842 0.0389666 0.0366961 4513 H3-3A/H2BC4/H2AC8/H3C6/H2BC6/H2AX/H2BC5/H2AJ/H3C11/H4C2/H2BC8/H2BC15/H2BC12/H2BC7/H2AC6/TAF1B/H4C9/H4C1/H3C1/H3C10/H4C3/H4C5/H2AC14/H2BC9/H4C6/H2AC4/H2BC17/H4C4/H3C8/H4C11/H3C7/H4C13/H4C12/H3C12/H2BC3/H3C13/H2BC13/H3C2/H2BC10/H3C3
REACTOME_HYALURONAN_METABOLISM 14 0.8472342 1.913146 0.0008695 0.0471588 0.0444109 183 HAS2/CEMIP/HYAL1/CD44/HAS3
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP 42 0.6691390 1.892147 0.0009319 0.0482481 0.0454367 1757 CYP51A1/LSS/MVD/DHCR7/FDPS/HMGCS1/HMGCR/SCD/ELOVL6/SREBF1/PMVK/FDFT1/IDI1/SC5D/FASN/HELZ2/SREBF2/MVK/SQLE

Pitavastatin vs Control

Volcano plots

ensembl baseMean log2FoldChange lfcSE stat pvalue padj ensembl_version protID prot_name gene ENTREZID description gene_biotype
ENSG00000160752 2805.163978 2.653624 0.0629724 42.139482 0.0000000 0.0000000 ENSG00000160752.15 A0A087X1D8 FDPS FDPS 2224 farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] protein_coding
ENSG00000052802 7032.630916 2.498560 0.0605930 41.235152 0.0000000 0.0000000 ENSG00000052802.13 Q15800 MSMO1 MSMO1 6307 methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] protein_coding
ENSG00000112972 7344.190156 3.167028 0.0689527 45.930448 0.0000000 0.0000000 ENSG00000112972.15 D6RIW1 HMGCS1 HMGCS1 3157 3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007] protein_coding
ENSG00000120437 1559.403451 3.425191 0.0797578 42.944887 0.0000000 0.0000000 ENSG00000120437.9 Q9BWD1 ACAT2 ACAT2 39 acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] protein_coding
ENSG00000186480 3171.726178 2.405319 0.0587864 40.916247 0.0000000 0.0000000 ENSG00000186480.13 C9JSG8 INSIG1 INSIG1 3638 insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] protein_coding
ENSG00000079459 5534.988758 2.155795 0.0572181 37.676817 0.0000000 0.0000000 ENSG00000079459.14 E9PSH1 FDFT1 FDFT1 2222 farnesyl-diphosphate farnesyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3629] protein_coding
ENSG00000134824 2545.745645 2.957245 0.0778084 38.006743 0.0000000 0.0000000 ENSG00000134824.14 O95864 FADS2 FADS2 9415 fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] protein_coding
ENSG00000167508 1108.457351 3.433271 0.0858614 39.986189 0.0000000 0.0000000 ENSG00000167508.12 H3BVC4 MVD MVD 4597 mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529] protein_coding
ENSG00000109084 671.850433 4.042981 0.1075812 37.580737 0.0000000 0.0000000 ENSG00000109084.14 J3KT68 TMEM97 TMEM97 27346 transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] protein_coding
ENSG00000172893 1728.173460 2.775901 0.0764319 36.318605 0.0000000 0.0000000 ENSG00000172893.18 A0A804HL56 DHCR7 DHCR7 1717 7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860] protein_coding
ENSG00000131069 1133.252872 2.808682 0.0789244 35.586980 0.0000000 0.0000000 ENSG00000131069.20 F8WC73 ACSS2 ACSS2 55902 acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814] protein_coding
ENSG00000160285 2227.956667 2.654603 0.0780047 34.031324 0.0000000 0.0000000 ENSG00000160285.15 P48449 LSS LSS 4047 lanosterol synthase [Source:HGNC Symbol;Acc:HGNC:6708] protein_coding
ENSG00000104549 3847.312430 1.826002 0.0551254 33.124485 0.0000000 0.0000000 ENSG00000104549.12 H0YBN7 SQLE SQLE 6713 squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] protein_coding
ENSG00000149485 1129.345081 2.414735 0.0762731 31.659077 0.0000000 0.0000000 ENSG00000149485.19 F5GWE3 FADS1 FADS1 3992 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] protein_coding
ENSG00000113161 5348.262899 2.409553 0.0761817 31.629043 0.0000000 0.0000000 ENSG00000113161.17 A0A7P0Z481 HMGCR HMGCR 3156 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] protein_coding
ENSG00000170522 747.561613 2.954600 0.0945632 31.244699 0.0000000 0.0000000 ENSG00000170522.10 D6RBP4 ELOVL6 ELOVL6 79071 ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] protein_coding
ENSG00000131473 4168.904656 2.022851 0.0679561 29.767009 0.0000000 0.0000000 ENSG00000131473.17 P53396 ACLY ACLY 47 ATP citrate lyase [Source:HGNC Symbol;Acc:HGNC:115] protein_coding
ENSG00000067064 6020.802801 2.274877 0.0791622 28.736901 0.0000000 0.0000000 ENSG00000067064.13 C9JD53 IDI1 IDI1 3422 isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] protein_coding
ENSG00000181577 311.753868 4.327537 0.1673629 25.857205 0.0000000 0.0000000 ENSG00000181577.16 LINC03040 221416 long intergenic non-protein coding RNA 3040 [Source:HGNC Symbol;Acc:HGNC:28692] lncRNA
ENSG00000109929 3622.935134 1.742625 0.0678624 25.678791 0.0000000 0.0000000 ENSG00000109929.10 O75845 SC5D SC5D 6309 sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547] protein_coding
ENSG00000149809 734.887185 2.050105 0.0808576 25.354519 0.0000000 0.0000000 ENSG00000149809.17 A0A024R577 TM7SF2 TM7SF2 7108 transmembrane 7 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11863] protein_coding
ENSG00000133935 2005.575618 1.762160 0.0714092 24.676937 0.0000000 0.0000000 ENSG00000133935.7 Q6FII3 C14orf1 ERG28 11161 ergosterol biosynthesis 28 homolog [Source:HGNC Symbol;Acc:HGNC:1187] protein_coding
ENSG00000164211 1367.739722 1.805509 0.0736390 24.518393 0.0000000 0.0000000 ENSG00000164211.13 Q96DR4 STARD4 STARD4 134429 StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058] protein_coding
ENSG00000151726 1901.774429 1.307718 0.0534577 24.462660 0.0000000 0.0000000 ENSG00000151726.16 E7EPM6 ACSL1 ACSL1 2180 acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569] protein_coding
ENSG00000169174 349.057488 3.000151 0.1233564 24.321010 0.0000000 0.0000000 ENSG00000169174.12 A0A669KAY4 PCSK9 PCSK9 255738 proprotein convertase subtilisin/kexin type 9 [Source:HGNC Symbol;Acc:HGNC:20001] protein_coding
ENSG00000099194 11321.691790 1.878950 0.0850242 22.098995 0.0000000 0.0000000 ENSG00000099194.6 O00767 SCD SCD 6319 stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] protein_coding
ENSG00000134324 814.864521 1.939563 0.0893103 21.717130 0.0000000 0.0000000 ENSG00000134324.12 C9J278 LPIN1 LPIN1 23175 lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] protein_coding
ENSG00000120137 3702.631019 1.035255 0.0478421 21.638996 0.0000000 0.0000000 ENSG00000120137.7 Q9H999 PANK3 PANK3 79646 pantothenate kinase 3 [Source:HGNC Symbol;Acc:HGNC:19365] protein_coding
ENSG00000130164 6399.332792 1.595539 0.0740220 21.554927 0.0000000 0.0000000 ENSG00000130164.15 P01130 LDLR LDLR 3949 low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547] protein_coding
ENSG00000147383 550.094132 1.921934 0.0910051 21.118979 0.0000000 0.0000000 ENSG00000147383.11 Q15738 NSDHL NSDHL 50814 NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] protein_coding
ENSG00000169710 6760.843765 1.567355 0.0748397 20.942839 0.0000000 0.0000000 ENSG00000169710.9 A0A0U1RRG3 FASN FASN 2194 fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594] protein_coding
ENSG00000119922 1029.786863 1.912123 0.0952306 20.078866 0.0000000 0.0000000 ENSG00000119922.11 P09913 IFIT2 IFIT2 3433 interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] protein_coding
ENSG00000137440 1914.021781 1.680899 0.0842527 19.950683 0.0000000 0.0000000 ENSG00000137440.5 Q14512 FGFBP1 FGFBP1 9982 fibroblast growth factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19695] protein_coding
ENSG00000119917 1557.788127 1.443370 0.0724450 19.923674 0.0000000 0.0000000 ENSG00000119917.15 Q5T765 IFIT3 IFIT3 3437 interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] protein_coding
ENSG00000132196 336.397053 2.192339 0.1107975 19.786909 0.0000000 0.0000000 ENSG00000132196.16 F2Z2C2 HSD17B7 HSD17B7 51478 hydroxysteroid 17-beta dehydrogenase 7 [Source:HGNC Symbol;Acc:HGNC:5215] protein_coding
ENSG00000110921 706.017328 1.442980 0.0729595 19.777829 0.0000000 0.0000000 ENSG00000110921.14 B2RDU6 MVK MVK 4598 mevalonate kinase [Source:HGNC Symbol;Acc:HGNC:7530] protein_coding
ENSG00000137959 1438.165434 1.694773 0.0861401 19.674616 0.0000000 0.0000000 ENSG00000137959.17 H7C1K6 IFI44L IFI44L 10964 interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] protein_coding
ENSG00000183486 976.124436 1.826331 0.1019542 17.913250 0.0000000 0.0000000 ENSG00000183486.14 P20592 MX2 MX2 4600 MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] protein_coding
ENSG00000101670 511.513788 2.009031 0.1153904 17.410730 0.0000000 0.0000000 ENSG00000101670.12 J3KTN7 LIPG LIPG 9388 lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] protein_coding
ENSG00000149084 2122.688599 1.137576 0.0659148 17.258286 0.0000000 0.0000000 ENSG00000149084.13 A0A1B0GVY6 HSD17B12 HSD17B12 51144 hydroxysteroid 17-beta dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:18646] protein_coding
ENSG00000187608 483.891237 1.759287 0.1023936 17.181601 0.0000000 0.0000000 ENSG00000187608.10 P05161 ISG15 ISG15 9636 ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] protein_coding
ENSG00000089127 1302.775685 1.226687 0.0727432 16.863249 0.0000000 0.0000000 ENSG00000089127.15 A0A7P0T960 OAS1 OAS1 4938 2’-5’-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] protein_coding
ENSG00000157601 2795.874836 1.201244 0.0721519 16.648812 0.0000000 0.0000000 ENSG00000157601.15 A0A7P0T9R0 MX1 MX1 4599 MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] protein_coding
ENSG00000134321 867.280605 1.735234 0.1044137 16.618837 0.0000000 0.0000000 ENSG00000134321.13 Q8WXG1 RSAD2 RSAD2 91543 radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] protein_coding
ENSG00000185745 1436.956152 1.462112 0.0893387 16.365945 0.0000000 0.0000000 ENSG00000185745.10 P09914 IFIT1 IFIT1 3434 interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] protein_coding
ENSG00000116133 9814.462372 1.002104 0.0613663 16.329879 0.0000000 0.0000000 ENSG00000116133.13 A0A3B3ISR5 DHCR24 DHCR24 1718 24-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2859] protein_coding
ENSG00000188211 328.520462 1.806916 0.1152843 15.673563 0.0000000 0.0000000 ENSG00000188211.9 Q68D85 NCR3LG1 NCR3LG1 374383 natural killer cell cytotoxicity receptor 3 ligand 1 [Source:HGNC Symbol;Acc:HGNC:42400] protein_coding
ENSG00000147155 160.927658 2.895848 0.1847596 15.673602 0.0000000 0.0000000 ENSG00000147155.11 A0A024QYX0 EBP EBP 10682 EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] protein_coding
ENSG00000068366 1006.666809 1.043088 0.0665864 15.665174 0.0000000 0.0000000 ENSG00000068366.21 A0A804HI36 ACSL4 ACSL4 2182 acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571] protein_coding
ENSG00000134326 590.713492 1.481533 0.0960921 15.417851 0.0000000 0.0000000 ENSG00000134326.12 Q5EBM0 CMPK2 CMPK2 129607 cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] protein_coding
ENSG00000111335 3116.959638 1.010970 0.0701279 14.416089 0.0000000 0.0000000 ENSG00000111335.14 F8W1C5 OAS2 OAS2 4939 2’-5’-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087] protein_coding
ENSG00000162512 385.143858 1.593844 0.1115325 14.290399 0.0000000 0.0000000 ENSG00000162512.16 O75056 SDC3 SDC3 9672 syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660] protein_coding
ENSG00000100344 89.280469 4.545122 0.3250722 13.981886 0.0000000 0.0000000 ENSG00000100344.11 F8W8E5 PNPLA3 PNPLA3 80339 patatin like phospholipase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18590] protein_coding
ENSG00000181381 960.135442 1.095030 0.0783961 13.967920 0.0000000 0.0000000 ENSG00000181381.15 D6RBA2 DDX60L DDX60L 91351 DExD/H-box 60 like [Source:HGNC Symbol;Acc:HGNC:26429] protein_coding
ENSG00000111331 2035.597144 1.427501 0.1022147 13.965715 0.0000000 0.0000000 ENSG00000111331.14 A0A7P0TAT5 OAS3 OAS3 4940 2’-5’-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] protein_coding
ENSG00000141458 1205.679848 1.183280 0.0849940 13.921931 0.0000000 0.0000000 ENSG00000141458.13 K7EIH7 NPC1 NPC1 4864 NPC intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7897] protein_coding
ENSG00000067082 2333.979576 1.007959 0.0752227 13.399666 0.0000000 0.0000000 ENSG00000067082.15 Q99612 KLF6 KLF6 1316 KLF transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] protein_coding
ENSG00000165949 2569.464068 1.004675 0.0750464 13.387389 0.0000000 0.0000000 ENSG00000165949.13 A0A087WV79 IFI27 IFI27 3429 interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397] protein_coding
ENSG00000134986 175.626323 1.811128 0.1356244 13.354004 0.0000000 0.0000000 ENSG00000134986.14 Q16612 NREP NREP 124906525 neuronal regeneration related protein [Source:HGNC Symbol;Acc:HGNC:16834] protein_coding
ENSG00000131203 816.376563 1.585435 0.1210799 13.094122 0.0000000 0.0000000 ENSG00000131203.13 A0A140T9Z2 IDO1 IDO1 3620 indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] protein_coding
ENSG00000092964 376.306596 1.403142 0.1074252 13.061577 0.0000000 0.0000000 ENSG00000092964.18 Q16555 DPYSL2 DPYSL2 1808 dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014] protein_coding
ENSG00000169474 145.726750 2.602308 0.1998328 13.022428 0.0000000 0.0000000 ENSG00000169474.5 P35321 SPRR1A SPRR1A 6698 small proline rich protein 1A [Source:HGNC Symbol;Acc:HGNC:11259] protein_coding
ENSG00000260630 119.701953 2.205558 0.1725537 12.781868 0.0000000 0.0000000 ENSG00000260630.9 SNAI3-AS1 197187 SNAI3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:28327] lncRNA
ENSG00000100075 596.256240 1.130224 0.0892966 12.656962 0.0000000 0.0000000 ENSG00000100075.10 P53007 SLC25A1 SLC25A1 6576 solute carrier family 25 member 1 [Source:HGNC Symbol;Acc:HGNC:10979] protein_coding
ENSG00000166920 810.985417 1.310560 0.1038003 12.625788 0.0000000 0.0000000 ENSG00000166920.13 Q9C002 NMES1 C15orf48 84419 chromosome 15 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29898] protein_coding
ENSG00000072042 745.522184 1.186941 0.0947147 12.531754 0.0000000 0.0000000 ENSG00000072042.13 G3V2G6 RDH11 RDH11 51109 retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] protein_coding
ENSG00000115919 1509.337440 1.089368 0.0876620 12.426910 0.0000000 0.0000000 ENSG00000115919.15 F8WEP1 KYNU KYNU 8942 kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] protein_coding
ENSG00000148600 81.951719 2.884824 0.2351762 12.266651 0.0000000 0.0000000 ENSG00000148600.15 Q96JP9 CDHR1 CDHR1 92211 cadherin related family member 1 [Source:HGNC Symbol;Acc:HGNC:14550] protein_coding
ENSG00000011422 293.386498 1.429881 0.1216972 11.749499 0.0000000 0.0000000 ENSG00000011422.12 M0R0L1 PLAUR PLAUR 5329 plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] protein_coding
ENSG00000172183 302.790277 1.422044 0.1218654 11.668978 0.0000000 0.0000000 ENSG00000172183.16 Q96AZ6 ISG20 ISG20 3669 interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] protein_coding
ENSG00000166396 673.589126 1.033543 0.0890208 11.610123 0.0000000 0.0000000 ENSG00000166396.13 O75635 SERPINB7 SERPINB7 8710 serpin family B member 7 [Source:HGNC Symbol;Acc:HGNC:13902] protein_coding
ENSG00000133106 339.843685 1.274739 0.1110763 11.476249 0.0000000 0.0000000 ENSG00000133106.15 F5H799 EPSTI1 EPSTI1 94240 epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] protein_coding
ENSG00000172840 467.250805 1.033676 0.0902133 11.458135 0.0000000 0.0000000 ENSG00000172840.7 H3BTU5 PDP2 PDP2 57546 pyruvate dehydrogenase phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:30263] protein_coding
ENSG00000173930 667.817481 1.111517 0.0977527 11.370707 0.0000000 0.0000000 ENSG00000173930.9 Q6ZQN7 SLCO4C1 SLCO4C1 353189 solute carrier organic anion transporter family member 4C1 [Source:HGNC Symbol;Acc:HGNC:23612] protein_coding
ENSG00000184227 99.076063 2.096737 0.1851475 11.324688 0.0000000 0.0000000 ENSG00000184227.8 Q86TX2 ACOT1 ACOT1 641371 acyl-CoA thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:33128] protein_coding
ENSG00000169583 161.382184 1.816624 0.1637493 11.093932 0.0000000 0.0000000 ENSG00000169583.13 O95833 CLIC3 CLIC3 9022 chloride intracellular channel 3 [Source:HGNC Symbol;Acc:HGNC:2064] protein_coding
ENSG00000151012 1268.876595 1.133795 0.1031543 10.991249 0.0000000 0.0000000 ENSG00000151012.13 H0Y9F9 SLC7A11 SLC7A11 23657 solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] protein_coding
ENSG00000130487 536.345822 1.190267 0.1092452 10.895374 0.0000000 0.0000000 ENSG00000130487.9 Q96G42 KLHDC7B KLHDC7B 113730 kelch domain containing 7B [Source:HGNC Symbol;Acc:HGNC:25145] protein_coding
ENSG00000126709 571.992656 1.297179 0.1195509 10.850435 0.0000000 0.0000000 ENSG00000126709.16 P09912 IFI6 IFI6 2537 interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] protein_coding
ENSG00000104689 461.572386 1.021020 0.0946654 10.785566 0.0000000 0.0000000 ENSG00000104689.10 O00220 TNFRSF10A TNFRSF10A 8797 TNF receptor superfamily member 10a [Source:HGNC Symbol;Acc:HGNC:11904] protein_coding
ENSG00000001630 68.042902 3.044665 0.2832596 10.748677 0.0000000 0.0000000 ENSG00000001630.18 Q16850 CYP51A1 CYP51A1 1595 cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649] protein_coding
ENSG00000008517 258.222766 1.463954 0.1362897 10.741488 0.0000000 0.0000000 ENSG00000008517.19 F8W1V1 IL32 IL32 9235 interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] protein_coding
ENSG00000132530 745.594585 1.032785 0.0965810 10.693461 0.0000000 0.0000000 ENSG00000132530.17 I3L534 XAF1 XAF1 54739 XIAP associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30932] protein_coding
ENSG00000065833 442.926257 1.129287 0.1062504 10.628543 0.0000000 0.0000000 ENSG00000065833.9 P48163 ME1 ME1 4199 malic enzyme 1 [Source:HGNC Symbol;Acc:HGNC:6983] protein_coding
ENSG00000100078 80.716038 4.600203 0.4329312 10.625715 0.0000000 0.0000000 ENSG00000100078.4 Q9NZ20 PLA2G3 PLA2G3 50487 phospholipase A2 group III [Source:HGNC Symbol;Acc:HGNC:17934] protein_coding
ENSG00000130589 1046.715817 1.037918 0.0984451 10.543121 0.0000000 0.0000000 ENSG00000130589.16 Q9BYK8 HELZ2 HELZ2 85441 helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] protein_coding
ENSG00000188761 1324.570586 1.102825 0.1052947 10.473695 0.0000000 0.0000000 ENSG00000188761.13 Q5TBC7 BCL2L15 BCL2L15 440603 BCL2 like 15 [Source:HGNC Symbol;Acc:HGNC:33624] protein_coding
ENSG00000171711 82.018488 3.207146 0.3064821 10.464381 0.0000000 0.0000000 ENSG00000171711.3 O15263 DEFB4A DEFB4A 124906748 defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] protein_coding
ENSG00000163993 811.690361 1.150136 0.1101329 10.443162 0.0000000 0.0000000 ENSG00000163993.7 P25815 S100P S100P 6286 S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] protein_coding
ENSG00000166670 774.945159 1.064967 0.1026207 10.377705 0.0000000 0.0000000 ENSG00000166670.10 P09238 MMP10 MMP10 4319 matrix metallopeptidase 10 [Source:HGNC Symbol;Acc:HGNC:7156] protein_coding
ENSG00000174669 126.412944 1.724417 0.1683600 10.242437 0.0000000 0.0000000 ENSG00000174669.12 Q14542 SLC29A2 SLC29A2 3177 solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] protein_coding
ENSG00000128342 263.484977 1.190470 0.1176740 10.116676 0.0000000 0.0000000 ENSG00000128342.5 P15018 LIF LIF 3976 LIF interleukin 6 family cytokine [Source:HGNC Symbol;Acc:HGNC:6596] protein_coding
ENSG00000101255 212.168911 1.521336 0.1507185 10.093888 0.0000000 0.0000000 ENSG00000101255.12 J3KR25 TRIB3 TRIB3 57761 tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228] protein_coding
ENSG00000135114 325.049251 1.423251 0.1426313 9.978531 0.0000000 0.0000000 ENSG00000135114.14 A0A7P0T9H8 OASL OASL 8638 2’-5’-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] protein_coding
ENSG00000181649 441.077488 1.050197 0.1081664 9.709085 0.0000000 0.0000000 ENSG00000181649.8 Q53GA4 PHLDA2 PHLDA2 7262 pleckstrin homology like domain family A member 2 [Source:HGNC Symbol;Acc:HGNC:12385] protein_coding
ENSG00000215424 87.277528 2.060269 0.2143670 9.610940 0.0000000 0.0000000 ENSG00000215424.10 MCM3AP-AS1 114044 MCM3AP antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:16417] lncRNA
ENSG00000160326 143.089433 1.906096 0.1987465 9.590587 0.0000000 0.0000000 ENSG00000160326.14 Q9UGQ3 SLC2A6 SLC2A6 11182 solute carrier family 2 member 6 [Source:HGNC Symbol;Acc:HGNC:11011] protein_coding
ENSG00000152137 256.485771 1.182194 0.1243120 9.509891 0.0000000 0.0000000 ENSG00000152137.8 A0A6Q8PGM6 HSPB8 HSPB8 26353 heat shock protein family B (small) member 8 [Source:HGNC Symbol;Acc:HGNC:30171] protein_coding
ENSG00000109107 174.576299 1.497441 0.1590826 9.412974 0.0000000 0.0000000 ENSG00000109107.14 C9J8F3 ALDOC ALDOC 230 aldolase, fructose-bisphosphate C [Source:HGNC Symbol;Acc:HGNC:418] protein_coding
ENSG00000185022 345.493630 1.084365 0.1160073 9.347385 0.0000000 0.0000000 ENSG00000185022.12 Q9ULX9 MAFF MAFF 23764 MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] protein_coding
ENSG00000214711 1144.254049 1.898450 0.2052772 9.248229 0.0000000 0.0000000 ENSG00000214711.10 A8MX76 CAPN14 CAPN14 440854 calpain 14 [Source:HGNC Symbol;Acc:HGNC:16664] protein_coding
ENSG00000114378 77.818016 2.393268 0.2592173 9.232672 0.0000000 0.0000000 ENSG00000114378.17 C9JRK1 HYAL1 HYAL1 3373 hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:5320] protein_coding
ENSG00000138821 432.396839 1.152550 0.1259311 9.152225 0.0000000 0.0000000 ENSG00000138821.14 Q9C0K1 SLC39A8 SLC39A8 64116 solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] protein_coding
ENSG00000158125 320.564865 1.196410 0.1316231 9.089666 0.0000000 0.0000000 ENSG00000158125.10 P47989 XDH XDH 7498 xanthine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:12805] protein_coding
ENSG00000007306 433.060563 1.177612 0.1317366 8.939142 0.0000000 0.0000000 ENSG00000007306.15 Q14002 CEACAM7 CEACAM7 1087 CEA cell adhesion molecule 7 [Source:HGNC Symbol;Acc:HGNC:1819] protein_coding
ENSG00000081041 136.454838 1.417262 0.1596058 8.879769 0.0000000 0.0000000 ENSG00000081041.9 P19875 CXCL2 CXCL2 2920 C-X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:4603] protein_coding
ENSG00000204520 170.001114 1.233658 0.1405644 8.776467 0.0000000 0.0000000 ENSG00000204520.14 A0A1W2PRA6 MICA MICA 100507436 MHC class I polypeptide-related sequence A [Source:HGNC Symbol;Acc:HGNC:7090] protein_coding
ENSG00000138685 217.835597 1.229031 0.1413836 8.692887 0.0000000 0.0000000 ENSG00000138685.18 P09038 FGF2 FGF2 2247 fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] protein_coding
ENSG00000078018 369.864288 1.121096 0.1294020 8.663668 0.0000000 0.0000000 ENSG00000078018.22 A0A669KB77 MAP2 MAP2 4133 microtubule associated protein 2 [Source:HGNC Symbol;Acc:HGNC:6839] protein_coding
ENSG00000185885 137.969198 1.499848 0.1743635 8.601845 0.0000000 0.0000000 ENSG00000185885.17 A0A7P0TB03 IFITM1 IFITM1 8519 interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] protein_coding
ENSG00000142227 114.748738 1.501734 0.1749089 8.585805 0.0000000 0.0000000 ENSG00000142227.11 M0QZ66 EMP3 EMP3 2014 epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] protein_coding
ENSG00000285427 35.841489 3.051923 0.3573678 8.540008 0.0000000 0.0000000 ENSG00000285427.1 SOD2-OT1 100129518 SOD2 overlapping transcript 1 [Source:HGNC Symbol;Acc:HGNC:53445] lncRNA
ENSG00000136688 112.484666 1.798894 0.2151643 8.360562 0.0000000 0.0000000 ENSG00000136688.11 C9J681 IL36G IL36G 56300 interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] protein_coding
ENSG00000128383 78.832706 2.574388 0.3080949 8.355828 0.0000000 0.0000000 ENSG00000128383.14 P31941 APOBEC3A APOBEC3A 100913187 apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] protein_coding
ENSG00000155918 126.183936 1.931388 0.2319704 8.326013 0.0000000 0.0000000 ENSG00000155918.8 Q5VY80 RAET1L RAET1L 154064 retinoic acid early transcript 1L [Source:HGNC Symbol;Acc:HGNC:16798] protein_coding
ENSG00000185479 498.536744 1.138946 0.1369303 8.317712 0.0000000 0.0000000 ENSG00000185479.6 P04259 KRT6B KRT6B 3854 keratin 6B [Source:HGNC Symbol;Acc:HGNC:6444] protein_coding
ENSG00000105327 154.606108 1.228244 0.1490238 8.241930 0.0000000 0.0000000 ENSG00000105327.18 Q96PG8 BBC3 BBC3 27113 BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] protein_coding
ENSG00000169248 76.225151 2.243346 0.2792000 8.034907 0.0000000 0.0000000 ENSG00000169248.13 O14625 CXCL11 CXCL11 6373 C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] protein_coding
ENSG00000134531 355.215614 1.090873 0.1367802 7.975377 0.0000000 0.0000000 ENSG00000134531.10 F5GYV0 EMP1 EMP1 2012 epithelial membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:3333] protein_coding
ENSG00000124882 196.608661 1.093041 0.1383084 7.902924 0.0000000 0.0000000 ENSG00000124882.4 O14944 EREG EREG 2069 epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] protein_coding
ENSG00000131067 173.246009 1.114674 0.1415696 7.873684 0.0000000 0.0000000 ENSG00000131067.17 Q9UJ14 GGT7 GGT7 2686 gamma-glutamyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4259] protein_coding
ENSG00000140379 71.226561 1.770491 0.2259859 7.834523 0.0000000 0.0000000 ENSG00000140379.9 Q16548 BCL2A1 BCL2A1 597 BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] protein_coding
ENSG00000112182 112.849949 1.407361 0.1799362 7.821442 0.0000000 0.0000000 ENSG00000112182.16 Q9BYV9 BACH2 BACH2 60468 BTB domain and CNC homolog 2 [Source:HGNC Symbol;Acc:HGNC:14078] protein_coding
ENSG00000289268 53.918169 2.091836 0.2688589 7.780424 0.0000000 0.0000000 ENSG00000289268.1 NA novel transcript lncRNA
ENSG00000251432 123.557900 1.469302 0.1933336 7.599825 0.0000000 0.0000000 ENSG00000251432.8 LINC02615 100507487 long intergenic non-protein coding RNA 2615 [Source:HGNC Symbol;Acc:HGNC:53402] lncRNA
ENSG00000169429 6723.677238 1.238296 0.1632241 7.586473 0.0000000 0.0000000 ENSG00000169429.12 C9J4T6 CXCL8 CXCL8 3576 C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] protein_coding
ENSG00000176907 248.611930 1.388884 0.1853095 7.494945 0.0000000 0.0000000 ENSG00000176907.5 Q9NR00 TCIM TCIM 56892 transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] protein_coding
ENSG00000233705 286.715205 1.237199 0.1693789 7.304327 0.0000000 0.0000000 ENSG00000233705.9 SLC26A4-AS1 NA SLC26A4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:22385] lncRNA
ENSG00000080031 114.740928 1.291200 0.1778084 7.261749 0.0000000 0.0000000 ENSG00000080031.10 Q9HD43 PTPRH PTPRH 5794 protein tyrosine phosphatase receptor type H [Source:HGNC Symbol;Acc:HGNC:9672] protein_coding
ENSG00000174502 44.345742 2.501095 0.3513528 7.118474 0.0000000 0.0000000 ENSG00000174502.19 Q7LBE3 SLC26A9 SLC26A9 115019 solute carrier family 26 member 9 [Source:HGNC Symbol;Acc:HGNC:14469] protein_coding
ENSG00000118508 144.727209 1.150895 0.1616876 7.118018 0.0000000 0.0000000 ENSG00000118508.5 Q13637 RAB32 RAB32 10981 RAB32, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9772] protein_coding
ENSG00000075673 4771.572999 1.086372 0.1547153 7.021749 0.0000000 0.0000000 ENSG00000075673.12 P54707 ATP12A ATP12A 479 ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] protein_coding
ENSG00000135318 204.413091 1.008856 0.1438431 7.013585 0.0000000 0.0000000 ENSG00000135318.12 P21589 NT5E NT5E 4907 5’-nucleotidase ecto [Source:HGNC Symbol;Acc:HGNC:8021] protein_coding
ENSG00000183963 84.037565 1.307453 0.1932723 6.764825 0.0000000 0.0000000 ENSG00000183963.19 B5MCI0 SMTN SMTN 6525 smoothelin [Source:HGNC Symbol;Acc:HGNC:11126] protein_coding
ENSG00000204618 138.054195 1.030190 0.1535226 6.710347 0.0000000 0.0000000 ENSG00000204618.10 A0A140T901 RNF39 RNF39 80352 ring finger protein 39 [Source:HGNC Symbol;Acc:HGNC:18064] protein_coding
ENSG00000169894 79.112638 1.473005 0.2197416 6.703354 0.0000000 0.0000000 ENSG00000169894.18 Q02505 MUC3A MUC3A 4584 mucin 3A, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7513] protein_coding
ENSG00000140519 73.143293 1.552744 0.2320873 6.690346 0.0000000 0.0000000 ENSG00000140519.14 H0YMF8 RHCG RHCG 51458 Rh family C glycoprotein [Source:HGNC Symbol;Acc:HGNC:18140] protein_coding
ENSG00000241794 149.938713 2.852693 0.4298381 6.636668 0.0000000 0.0000000 ENSG00000241794.2 P35326 SPRR2A SPRR2A 6700 small proline rich protein 2A [Source:HGNC Symbol;Acc:HGNC:11261] protein_coding
ENSG00000174327 216.635704 1.009136 0.1524308 6.620288 0.0000000 0.0000000 ENSG00000174327.7 Q7RTY0 SLC16A13 SLC16A13 201232 solute carrier family 16 member 13 [Source:HGNC Symbol;Acc:HGNC:31037] protein_coding
ENSG00000167123 89.748562 1.633488 0.2475620 6.598299 0.0000000 0.0000000 ENSG00000167123.20 X6RL83 CERCAM CERCAM 51148 cerebral endothelial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:23723] protein_coding
ENSG00000100170 273.414767 1.115436 0.1703177 6.549146 0.0000000 0.0000000 ENSG00000100170.10 P13866 SLC5A1 SLC5A1 6523 solute carrier family 5 member 1 [Source:HGNC Symbol;Acc:HGNC:11036] protein_coding
ENSG00000050730 142.937001 1.405152 0.2152947 6.526644 0.0000000 0.0000000 ENSG00000050730.16 Q96KP6 TNIP3 TNIP3 79931 TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] protein_coding
ENSG00000162551 148.270545 1.105999 0.1714062 6.452504 0.0000000 0.0000000 ENSG00000162551.14 A0A024RAB4 ALPL ALPL 249 alkaline phosphatase, biomineralization associated [Source:HGNC Symbol;Acc:HGNC:438] protein_coding
ENSG00000260196 45.951970 1.854222 0.2877198 6.444540 0.0000000 0.0000000 ENSG00000260196.1 NA antisense to KCNJ11 and overlapping to a novel gene lncRNA
ENSG00000125657 101.371502 1.267060 0.1966789 6.442275 0.0000000 0.0000000 ENSG00000125657.5 P41273 TNFSF9 TNFSF9 8744 TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939] protein_coding
ENSG00000166535 102.981758 1.138113 0.1798999 6.326369 0.0000000 0.0000000 ENSG00000166535.20 F5GXP1 A2ML1 A2ML1 144568 alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336] protein_coding
ENSG00000114268 91.866128 1.295686 0.2057314 6.297951 0.0000000 0.0000000 ENSG00000114268.12 C9JX77 PFKFB4 PFKFB4 5210 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:HGNC Symbol;Acc:HGNC:8875] protein_coding
ENSG00000184574 115.500546 1.056288 0.1696583 6.225974 0.0000000 0.0000000 ENSG00000184574.10 Q9H1C0 LPAR5 LPAR5 57121 lysophosphatidic acid receptor 5 [Source:HGNC Symbol;Acc:HGNC:13307] protein_coding
ENSG00000125538 148.824582 1.004830 0.1637825 6.135147 0.0000000 0.0000000 ENSG00000125538.12 C9JWV2 IL1B IL1B 3553 interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] protein_coding
ENSG00000278952 14.596015 3.719939 0.6102154 6.096108 0.0000000 0.0000000 ENSG00000278952.1 NA TEC TEC
ENSG00000130775 41.092606 1.776048 0.2938809 6.043427 0.0000000 0.0000001 ENSG00000130775.16 X6RK39 THEMIS2 THEMIS2 9473 thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] protein_coding
ENSG00000182134 82.106848 1.184780 0.1975866 5.996258 0.0000000 0.0000001 ENSG00000182134.17 B7ZAG4 TDRKH TDRKH 11022 tudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713] protein_coding
ENSG00000124102 1400.208201 1.081266 0.1828816 5.912384 0.0000000 0.0000001 ENSG00000124102.5 P19957 PI3 PI3 5266 peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947] protein_coding
ENSG00000163209 253.161053 1.997138 0.3385471 5.899146 0.0000000 0.0000001 ENSG00000163209.15 Q9UBC9 SPRR3 SPRR3 6707 small proline rich protein 3 [Source:HGNC Symbol;Acc:HGNC:11268] protein_coding
ENSG00000285820 73.079411 1.274673 0.2218025 5.746881 0.0000000 0.0000003 ENSG00000285820.1 NA Novel transcript, antisense to ASTN2 lncRNA
ENSG00000138166 530.496274 1.429529 0.2509246 5.697044 0.0000000 0.0000004 ENSG00000138166.6 Q16690 DUSP5 DUSP5 1847 dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] protein_coding
ENSG00000130956 80.069633 1.142961 0.2007178 5.694369 0.0000000 0.0000004 ENSG00000130956.14 Q5JVS0 HABP4 HABP4 22927 hyaluronan binding protein 4 [Source:HGNC Symbol;Acc:HGNC:17062] protein_coding
ENSG00000257337 76.300521 1.135861 0.1995614 5.691788 0.0000000 0.0000004 ENSG00000257337.9 TNS2-AS1 283335 TNS2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27464] lncRNA
ENSG00000124875 479.804031 1.362375 0.2448006 5.565243 0.0000000 0.0000008 ENSG00000124875.10 D6RF92 CXCL6 CXCL6 6372 C-X-C motif chemokine ligand 6 [Source:HGNC Symbol;Acc:HGNC:10643] protein_coding
ENSG00000049249 24.422051 2.381968 0.4286005 5.557548 0.0000000 0.0000008 ENSG00000049249.10 Q07011 TNFRSF9 TNFRSF9 3604 TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] protein_coding
ENSG00000169245 285.008493 2.418032 0.4388132 5.510390 0.0000000 0.0000010 ENSG00000169245.6 P02778 CXCL10 CXCL10 3627 C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] protein_coding
ENSG00000163121 57.878490 1.189966 0.2191993 5.428692 0.0000001 0.0000016 ENSG00000163121.10 A0A087WXE0 NEURL3 NEURL3 93082 neuralized E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:25162] protein_coding
ENSG00000130208 13.334621 3.716287 0.6906661 5.380729 0.0000001 0.0000020 ENSG00000130208.10 P02654 APOC1 APOC1 341 apolipoprotein C1 [Source:HGNC Symbol;Acc:HGNC:607] protein_coding
ENSG00000230533 29.693138 1.755437 0.3288366 5.338326 0.0000001 0.0000025 ENSG00000230533.5 LINC03004 102723649 long intergenic non-protein coding RNA 3004 [Source:HGNC Symbol;Acc:HGNC:56128] lncRNA
ENSG00000067191 54.231281 1.315782 0.2479254 5.307167 0.0000001 0.0000029 ENSG00000067191.17 Q02641 CACNB1 CACNB1 782 calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] protein_coding
ENSG00000102384 62.088355 1.122301 0.2142299 5.238771 0.0000002 0.0000041 ENSG00000102384.14 Q5JX01 CENPI CENPI 2491 centromere protein I [Source:HGNC Symbol;Acc:HGNC:3968] protein_coding
ENSG00000127528 141.467140 1.064822 0.2053186 5.186191 0.0000002 0.0000054 ENSG00000127528.6 Q9Y5W3 KLF2 KLF2 10365 KLF transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:6347] protein_coding
ENSG00000145335 60.343412 1.169408 0.2307020 5.068911 0.0000004 0.0000094 ENSG00000145335.17 P37840 SNCA SNCA 6622 synuclein alpha [Source:HGNC Symbol;Acc:HGNC:11138] protein_coding
ENSG00000204544 24.486149 2.097427 0.4170258 5.029488 0.0000005 0.0000115 ENSG00000204544.5 Q5SSG8 MUC21 MUC21 394263 mucin 21, cell surface associated [Source:HGNC Symbol;Acc:HGNC:21661] protein_coding
ENSG00000040608 61.052075 1.398928 0.2789746 5.014534 0.0000005 0.0000123 ENSG00000040608.14 Q9BZR6 RTN4R RTN4R 65078 reticulon 4 receptor [Source:HGNC Symbol;Acc:HGNC:18601] protein_coding
ENSG00000283930 19.564458 2.348916 0.4718620 4.977974 0.0000006 0.0000146 ENSG00000283930.1 A0A1W2PQ67 PLD5P1 PLD5P1 NA PLD5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:55072] protein_coding
ENSG00000102962 23.156425 1.856610 0.3749712 4.951341 0.0000007 0.0000166 ENSG00000102962.5 O00626 CCL22 CCL22 6367 C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] protein_coding
ENSG00000160471 82.592058 1.017838 0.2069009 4.919447 0.0000009 0.0000193 ENSG00000160471.13 Q6YFQ2 COX6B2 COX6B2 125965 cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] protein_coding
ENSG00000115009 1011.460751 1.518471 0.3093005 4.909371 0.0000009 0.0000202 ENSG00000115009.13 P78556 CCL20 CCL20 6364 C-C motif chemokine ligand 20 [Source:HGNC Symbol;Acc:HGNC:10619] protein_coding
ENSG00000196408 40.340224 1.373344 0.2800503 4.903918 0.0000009 0.0000208 ENSG00000196408.12 Q8NFA2 NOXO1 NOXO1 124056 NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] protein_coding
ENSG00000099251 32.300115 1.978350 0.4056146 4.877413 0.0000011 0.0000233 ENSG00000099251.15 HSD17B7P2 NA hydroxysteroid 17-beta dehydrogenase 7 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28120] transcribed_unprocessed_pseudogene
ENSG00000256870 167.124294 1.053472 0.2212337 4.761806 0.0000019 0.0000395 ENSG00000256870.3 Q8N695 SLC5A8 SLC5A8 160728 solute carrier family 5 member 8 [Source:HGNC Symbol;Acc:HGNC:19119] protein_coding
ENSG00000275552 14.639784 2.733514 0.5760995 4.744865 0.0000021 0.0000426 ENSG00000275552.1 NA novel transcript, antisense ABHD4 lncRNA
ENSG00000105499 44.225486 1.284067 0.2714190 4.730942 0.0000022 0.0000451 ENSG00000105499.14 M0R1B4 PLA2G4C PLA2G4C 8605 phospholipase A2 group IVC [Source:HGNC Symbol;Acc:HGNC:9037] protein_coding
ENSG00000186792 48.912841 1.193581 0.2523659 4.729566 0.0000023 0.0000453 ENSG00000186792.17 O43820 HYAL3 HYAL3 8372 hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] protein_coding
ENSG00000273117 54.156761 1.046711 0.2215690 4.724088 0.0000023 0.0000464 ENSG00000273117.1 INSIG1-DT NA INSIG1 divergent transcript [Source:HGNC Symbol;Acc:HGNC:55155] lncRNA
ENSG00000168062 82.105884 1.035155 0.2230243 4.641442 0.0000035 0.0000668 ENSG00000168062.10 Q8N1L9 BATF2 BATF2 116071 basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] protein_coding
ENSG00000169896 41.588633 1.178416 0.2656124 4.436601 0.0000091 0.0001588 ENSG00000169896.18 P11215 ITGAM ITGAM 3684 integrin subunit alpha M [Source:HGNC Symbol;Acc:HGNC:6149] protein_coding
ENSG00000163734 58.969228 1.319679 0.3037392 4.344778 0.0000139 0.0002325 ENSG00000163734.4 P19876 CXCL3 CXCL3 2921 C-X-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:4604] protein_coding
ENSG00000163216 148.187531 1.893048 0.4374579 4.327383 0.0000151 0.0002488 ENSG00000163216.7 P22532 SPRR2D SPRR2D 6703 small proline rich protein 2D [Source:HGNC Symbol;Acc:HGNC:11264] protein_coding
ENSG00000142224 87.996501 1.977117 0.4585731 4.311454 0.0000162 0.0002648 ENSG00000142224.18 Q9UHD0 IL19 IL19 29949 interleukin 19 [Source:HGNC Symbol;Acc:HGNC:5990] protein_coding
ENSG00000286225 51.671652 1.001126 0.2324369 4.307086 0.0000165 0.0002690 ENSG00000286225.1 NA novel transcript lncRNA
ENSG00000143556 11.090935 2.657785 0.6180735 4.300111 0.0000171 0.0002759 ENSG00000143556.9 P31151 S100A7 S100A7 6278 S100 calcium binding protein A7 [Source:HGNC Symbol;Acc:HGNC:10497] protein_coding
ENSG00000164949 18.239389 2.141590 0.4993158 4.289048 0.0000179 0.0002881 ENSG00000164949.8 P55040 GEM GEM 2669 GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] protein_coding
ENSG00000128052 210.553750 1.147727 0.2702765 4.246493 0.0000217 0.0003408 ENSG00000128052.10 P35968 KDR KDR 3791 kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307] protein_coding
ENSG00000223784 70.968096 1.208134 0.2846720 4.243951 0.0000220 0.0003442 ENSG00000223784.2 LINP1 NA lncRNA in non-homologous end joining pathway 1 [Source:HGNC Symbol;Acc:HGNC:53170] lncRNA
ENSG00000244094 9.743436 3.054122 0.7299413 4.184065 0.0000286 0.0004324 ENSG00000244094.2 Q96RM1 SPRR2F SPRR2F 6705 small proline rich protein 2F [Source:HGNC Symbol;Acc:HGNC:11266] protein_coding
ENSG00000123358 31.191040 1.344449 0.3243896 4.144551 0.0000340 0.0005055 ENSG00000123358.20 H3BSM8 NR4A1 NR4A1 3164 nuclear receptor subfamily 4 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7980] protein_coding
ENSG00000196972 8.047097 3.390222 0.8197229 4.135815 0.0000354 0.0005225 ENSG00000196972.9 P0DMW5 SMIM10L2B SMIM10L2B 644596 small integral membrane protein 10 like 2B [Source:HGNC Symbol;Acc:HGNC:34500] protein_coding
ENSG00000182600 31.706311 1.253314 0.3037523 4.126104 0.0000369 0.0005423 ENSG00000182600.10 Q6UX34 SNORC SNORC 389084 secondary ossification center associated regulator of chondrocyte maturation [Source:HGNC Symbol;Acc:HGNC:33763] protein_coding
ENSG00000175505 47.226511 1.051497 0.2601137 4.042452 0.0000529 0.0007485 ENSG00000175505.11 Q9UBD9 CLCF1 CLCF1 23529 cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412] protein_coding
ENSG00000203785 11.013187 3.627770 0.9071507 3.999082 0.0000636 0.0008810 ENSG00000203785.9 P22531 SPRR2E SPRR2E 6704 small proline rich protein 2E [Source:HGNC Symbol;Acc:HGNC:11265] protein_coding
ENSG00000205325 24.271271 1.345023 0.3378462 3.981170 0.0000686 0.0009374 ENSG00000205325.4 NA novel transcript lncRNA
ENSG00000163221 21.150524 1.477953 0.3740124 3.951614 0.0000776 0.0010428 ENSG00000163221.9 P80511 S100A12 S100A12 6283 S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489] protein_coding
ENSG00000164825 45.207069 1.004382 0.2583233 3.888081 0.0001010 0.0013164 ENSG00000164825.4 P60022 DEFB1 DEFB1 1672 defensin beta 1 [Source:HGNC Symbol;Acc:HGNC:2766] protein_coding
ENSG00000253522 52.233824 1.060836 0.2765946 3.835347 0.0001254 0.0015741 ENSG00000253522.6 MIR3142HG 107075116 MIR3142 host gene [Source:HGNC Symbol;Acc:HGNC:51944] lncRNA
ENSG00000105246 16.690517 1.844978 0.4901046 3.764458 0.0001669 0.0020216 ENSG00000105246.6 Q14213 EBI3 EBI3 10148 Epstein-Barr virus induced 3 [Source:HGNC Symbol;Acc:HGNC:3129] protein_coding
ENSG00000235947 11.455258 1.979997 0.5262961 3.762135 0.0001685 0.0020381 ENSG00000235947.1 EGOT 100126791 eosinophil granule ontogeny transcript [Source:HGNC Symbol;Acc:HGNC:37129] lncRNA
ENSG00000286042 27.827205 1.549261 0.4133518 3.748044 0.0001782 0.0021307 ENSG00000286042.1 LCAL1 80078 lung cancer associated lncRNA 1 [Source:HGNC Symbol;Acc:HGNC:25837] lncRNA
ENSG00000124256 8.249823 3.238223 0.8655542 3.741214 0.0001831 0.0021806 ENSG00000124256.15 Q9H171 ZBP1 ZBP1 81030 Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] protein_coding
ENSG00000233588 9.015725 2.807974 0.7545587 3.721345 0.0001982 0.0023253 ENSG00000233588.1 CYP51A1P2 NA cytochrome P450 family 51 subfamily A member 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:20251] processed_pseudogene
ENSG00000009950 12.256248 1.866217 0.5131227 3.636981 0.0002759 0.0030901 ENSG00000009950.16 Q9NP71 MLXIPL MLXIPL 51085 MLX interacting protein like [Source:HGNC Symbol;Acc:HGNC:12744] protein_coding
ENSG00000091137 2888.864863 1.100261 0.3042740 3.616019 0.0002992 0.0033098 ENSG00000091137.14 O43511 SLC26A4 SLC26A4 5172 solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] protein_coding
ENSG00000225298 31.785445 1.297691 0.3600002 3.604694 0.0003125 0.0034239 ENSG00000225298.5 LINC00113 54088 long intergenic non-protein coding RNA 113 [Source:HGNC Symbol;Acc:HGNC:1264] lncRNA
ENSG00000249051 11.907631 1.972795 0.5474228 3.603787 0.0003136 0.0034340 ENSG00000249051.2 NA chromosome 11 open reading frame 73 (C11orf73) pseudogene processed_pseudogene
ENSG00000167105 45.068217 1.049336 0.2919446 3.594299 0.0003253 0.0035444 ENSG00000167105.8 Q6UXU6 TMEM92 TMEM92 162461 transmembrane protein 92 [Source:HGNC Symbol;Acc:HGNC:26579] protein_coding
ENSG00000215853 26.845844 1.790663 0.4986829 3.590786 0.0003297 0.0035881 ENSG00000215853.3 Q6XPR3 RPTN RPTN 126638 repetin [Source:HGNC Symbol;Acc:HGNC:26809] protein_coding
ENSG00000167799 25.321416 1.146844 0.3319384 3.454990 0.0005503 0.0055612 ENSG00000167799.10 Q8WV74 NUDT8 NUDT8 254552 nudix hydrolase 8 [Source:HGNC Symbol;Acc:HGNC:8055] protein_coding
ENSG00000160867 9.201274 2.149148 0.6325798 3.397434 0.0006802 0.0066585 ENSG00000160867.15 P22455 FGFR4 FGFR4 2264 fibroblast growth factor receptor 4 [Source:HGNC Symbol;Acc:HGNC:3691] protein_coding
ENSG00000271503 37.529621 1.067699 0.3153109 3.386179 0.0007087 0.0069011 ENSG00000271503.7 P13501 CCL5 CCL5 6352 C-C motif chemokine ligand 5 [Source:HGNC Symbol;Acc:HGNC:10632] protein_coding
ENSG00000059377 38.886152 1.150440 0.3533421 3.255880 0.0011304 0.0103646 ENSG00000059377.19 C9JS68 TBXAS1 TBXAS1 6916 thromboxane A synthase 1 [Source:HGNC Symbol;Acc:HGNC:11609] protein_coding
ENSG00000125726 10.898438 1.807339 0.5600093 3.227338 0.0012495 0.0112547 ENSG00000125726.11 M0QZW2 CD70 CD70 970 CD70 molecule [Source:HGNC Symbol;Acc:HGNC:11937] protein_coding
ENSG00000171476 45.407356 1.200371 0.3721462 3.225538 0.0012574 0.0113051 ENSG00000171476.23 Q9BPY8 HOPX HOPX 84525 HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961] protein_coding
ENSG00000240694 21.430768 1.260841 0.3913830 3.221501 0.0012752 0.0114156 ENSG00000240694.9 Q9UL42 PNMA2 PNMA2 10687 PNMA family member 2 [Source:HGNC Symbol;Acc:HGNC:9159] protein_coding
ENSG00000262823 16.026864 1.432280 0.4468736 3.205112 0.0013501 0.0119648 ENSG00000262823.1 NA novel transcript, antisense to SPNS3 lncRNA
ENSG00000250508 7.225011 2.359702 0.7405249 3.186526 0.0014399 0.0126504 ENSG00000250508.1 LINC02701 NA long intergenic non-protein coding RNA 2701 [Source:HGNC Symbol;Acc:HGNC:54216] lncRNA
ENSG00000166736 14.971022 1.474290 0.4659387 3.164130 0.0015555 0.0135136 ENSG00000166736.12 P46098 HTR3A HTR3A 3359 5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297] protein_coding
ENSG00000231205 15.873128 1.282088 0.4057499 3.159798 0.0015788 0.0136868 ENSG00000231205.14 ZNF826P NA zinc finger protein 826, pseudogene [Source:HGNC Symbol;Acc:HGNC:33875] transcribed_unprocessed_pseudogene
ENSG00000047936 23.453057 1.043742 0.3337853 3.126985 0.0017661 0.0150599 ENSG00000047936.11 P08922 ROS1 ROS1 6098 ROS proto-oncogene 1, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10261] protein_coding
ENSG00000144843 26.301671 1.103194 0.3531306 3.124039 0.0017839 0.0151746 ENSG00000144843.12 P54922 ADPRH ADPRH 141 ADP-ribosylarginine hydrolase [Source:HGNC Symbol;Acc:HGNC:269] protein_coding
ENSG00000198910 16.355538 1.264898 0.4057839 3.117172 0.0018260 0.0154580 ENSG00000198910.14 P32004 L1CAM L1CAM 3897 L1 cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:6470] protein_coding
ENSG00000255173 4.724958 2.731564 0.8766760 3.115819 0.0018344 0.0155053 ENSG00000255173.1 NA novel transcript lncRNA
ENSG00000139329 5.020862 2.861013 0.9251203 3.092585 0.0019842 0.0165585 ENSG00000139329.5 P51884 LUM LUM 4060 lumican [Source:HGNC Symbol;Acc:HGNC:6724] protein_coding
ENSG00000125144 7.006583 2.229477 0.7220174 3.087844 0.0020161 0.0167434 ENSG00000125144.14 P13640 MT1G MT1G 4495 metallothionein 1G [Source:HGNC Symbol;Acc:HGNC:7399] protein_coding
ENSG00000103485 6.488084 2.213175 0.7169624 3.086878 0.0020227 0.0167763 ENSG00000103485.19 Q15274 QPRT QPRT 23475 quinolinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:9755] protein_coding
ENSG00000087085 4.991205 3.261662 1.0596716 3.077993 0.0020840 0.0172424 ENSG00000087085.16 C9JZL6 ACHE ACHE 43 acetylcholinesterase (Cartwright blood group) [Source:HGNC Symbol;Acc:HGNC:108] protein_coding
ENSG00000075035 16.398898 1.337459 0.4421418 3.024955 0.0024867 0.0197923 ENSG00000075035.10 Q2TBF2 WSCD2 WSCD2 9671 WSC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29117] protein_coding
ENSG00000219891 26.308695 1.058991 0.3528393 3.001342 0.0026879 0.0210312 ENSG00000219891.4 ZSCAN12P1 NA zinc finger and SCAN domain containing 12 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13850] transcribed_unprocessed_pseudogene
ENSG00000130558 16.487359 1.327284 0.4474701 2.966195 0.0030151 0.0231892 ENSG00000130558.20 Q99784 OLFM1 OLFM1 10439 olfactomedin 1 [Source:HGNC Symbol;Acc:HGNC:17187] protein_coding
ENSG00000288695 20.700774 1.300951 0.4404807 2.953481 0.0031421 0.0239845 ENSG00000288695.1 NA novel protein, SRD5A3-RP11-177J6.1 readthrough protein_coding
ENSG00000005108 8.541624 2.090195 0.7118129 2.936439 0.0033200 0.0250787 ENSG00000005108.17 Q9UPZ6 THSD7A THSD7A 221981 thrombospondin type 1 domain containing 7A [Source:HGNC Symbol;Acc:HGNC:22207] protein_coding
ENSG00000008735 22.743388 1.126412 0.3844717 2.929766 0.0033922 0.0255008 ENSG00000008735.14 Q13387 MAPK8IP2 MAPK8IP2 23542 mitogen-activated protein kinase 8 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:6883] protein_coding
ENSG00000131459 9.243603 1.837905 0.6281557 2.925876 0.0034349 0.0257356 ENSG00000131459.13 A0A0S2Z4X9 GFPT2 GFPT2 9945 glutamine-fructose-6-phosphate transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4242] protein_coding
ENSG00000115602 33.881709 1.008627 0.3461353 2.913967 0.0035687 0.0265131 ENSG00000115602.17 C9JSY6 IL1RL1 IL1RL1 9173 interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] protein_coding
ENSG00000010438 12.515845 1.630110 0.5635082 2.892789 0.0038184 0.0280807 ENSG00000010438.17 A0A7P0MP65 PRSS3 PRSS3 5646 serine protease 3 [Source:HGNC Symbol;Acc:HGNC:9486] protein_coding
ENSG00000087128 15.694356 1.442934 0.5030555 2.868340 0.0041263 0.0299121 ENSG00000087128.10 A0A0G2JNI0 TMPRSS11E TMPRSS11E 28983 transmembrane serine protease 11E [Source:HGNC Symbol;Acc:HGNC:24465] protein_coding
ENSG00000241095 3.691705 3.534221 1.2322960 2.867997 0.0041308 0.0299232 ENSG00000241095.1 CYP51A1P1 NA cytochrome P450 family 51 subfamily A member 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:20245] processed_pseudogene
ENSG00000229563 4.194691 2.777766 0.9728308 2.855344 0.0042990 0.0309344 ENSG00000229563.7 LINC01204 101927528 long intergenic non-protein coding RNA 1204 [Source:HGNC Symbol;Acc:HGNC:49635] lncRNA
ENSG00000287051 9.017992 1.726321 0.6066704 2.845567 0.0044332 0.0316513 ENSG00000287051.1 NA novel transcript, antisense to KRT86 lncRNA
ENSG00000228137 6.080964 2.236307 0.8026242 2.786244 0.0053323 0.0365539 ENSG00000228137.1 NA novel transcript lncRNA
ENSG00000269906 10.999235 1.509664 0.5456885 2.766531 0.0056656 0.0384429 ENSG00000269906.1 NA novel transcript, sense intronic to SAV1 lncRNA
ENSG00000254682 21.958851 1.010510 0.3660660 2.760459 0.0057720 0.0390035 ENSG00000254682.2 DHCR7-DT NA DHCR7 divergent transcript [Source:HGNC Symbol;Acc:HGNC:56822] lncRNA
ENSG00000156510 16.126953 1.459855 0.5317365 2.745448 0.0060428 0.0404058 ENSG00000156510.13 Q2TB90 HKDC1 HKDC1 80201 hexokinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23302] protein_coding
ENSG00000213398 25.014343 1.018536 0.3709706 2.745598 0.0060401 0.0404058 ENSG00000213398.8 P04180 LCAT LCAT 3931 lecithin-cholesterol acyltransferase [Source:HGNC Symbol;Acc:HGNC:6522] protein_coding
ENSG00000136274 13.567995 1.414980 0.5190583 2.726053 0.0064097 0.0424359 ENSG00000136274.9 O15069 NACAD NACAD 23148 NAC alpha domain containing [Source:HGNC Symbol;Acc:HGNC:22196] protein_coding
ENSG00000158560 4.744683 2.772203 1.0186390 2.721477 0.0064991 0.0429299 ENSG00000158560.14 C9J3E7 DYNC1I1 DYNC1I1 1780 dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963] protein_coding
ENSG00000188404 34.418413 1.112700 0.4135316 2.690725 0.0071297 0.0461940 ENSG00000188404.10 P14151 SELL SELL 6402 selectin L [Source:HGNC Symbol;Acc:HGNC:10720] protein_coding

GSEA analysis (logFc)

GOBP

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
GOBP_MITOTIC_SISTER_CHROMATID_SEGREGATION 162 -0.6738627 -2.608508 0.0000000 0.0000000 0.0000000 1174 MAP10/RACGAP1/FBXO5/DSCC1/ANAPC4/MAD1L1/TRIP13/CCNB1/CDCA8/HASPIN/CENPK/KIF18A/PSRC1/ZWINT/PTTG1/KIF23/SGO2/CDT1/CENPF/ESPL1/KIF14/TACC3/TTK/MAD2L1/SPAG5/NDC80/PLK1/CENPE/NEK2/CDCA5/KIF4A/BUB1/DLGAP5/NUF2/KIF2C/CDC20/NCAPH/KIFC1/SGO1/BUB1B/UBE2C/CEP55/NCAPG/KIF18B
GOBP_SISTER_CHROMATID_SEGREGATION 188 -0.6545741 -2.599064 0.0000000 0.0000000 0.0000000 1339 RMI2/AXIN2/MAP10/RACGAP1/FBXO5/DSCC1/ANAPC4/MAD1L1/TRIP13/CCNB1/CDCA8/HASPIN/CENPK/KIF18A/PSRC1/ZWINT/PTTG1/KIF23/SGO2/CDT1/CENPF/ESPL1/KIF14/TACC3/TTK/MAD2L1/SPAG5/NDC80/PLK1/CENPE/NEK2/ESCO2/CDCA5/KIF4A/BUB1/DLGAP5/NUF2/KIF2C/CDC20/NCAPH/KIFC1/SGO1/BUB1B/UBE2C/TOP2A/CEP55/NCAPG/KIF18B
GOBP_NUCLEOSOME_ASSEMBLY 94 -0.6897309 -2.491192 0.0000000 0.0000000 0.0000000 1304 CHAF1B/H3C1/H3C13/H3C10/H2BC11/H2BC3/HMGB2/H4C13/CENPP/H2BC7/H2BC10/H4C1/OIP5/H3C7/H4C9/H1-5/ASF1B/H3C12/H2BC17/H1-1/H2BC13/H3C3/H2BC14/H3C8/H3C2/HJURP
GOBP_CHROMOSOME_SEGREGATION 308 -0.5937955 -2.485779 0.0000000 0.0000000 0.0000000 864 BRIP1/ANAPC4/CCNE1/MAD1L1/TRIP13/CCNB1/MAJIN/CDCA8/HASPIN/CENPK/KIF18A/PSRC1/ZWINT/PTTG1/KIF23/SGO2/CDT1/CENPF/SPC24/ESPL1/KIF14/FAM83D/CCNE2/TACC3/OIP5/TTK/MAD2L1/SKA3/SPAG5/KNL1/NDC80/PLK1/CENPE/NEK2/ESCO2/CDCA5/KIF4A/BUB1/DLGAP5/NUF2/KIF2C/CDCA2/SKA1/DMC1/CDC20/NCAPH/KIFC1/SGO1/BUB1B/UBE2C/TOP2A/CEP55/NCAPG/SPC25/KIF18B/MKI67/HJURP
GOBP_REGULATION_OF_CHROMOSOME_SEGREGATION 81 -0.6951128 -2.472131 0.0000000 0.0000000 0.0000000 861 HECW2/XRCC3/MAPK15/RMI2/FBXO5/ANAPC4/MAD1L1/TRIP13/CCNB1/ZWINT/PTTG1/CDT1/CENPF/ESPL1/TACC3/TTK/MAD2L1/NDC80/PLK1/CENPE/BUB1/DLGAP5/KIF2C/CDCA2/BUB1B/UBE2C/MKI67
GOBP_STEROL_BIOSYNTHETIC_PROCESS 53 0.8004700 2.469437 0.0000000 0.0000000 0.0000000 398 MVD/HMGCS1/CYP51A1/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/TM7SF2/ACLY/NSDHL/SQLE/ERG28/SC5D/MVK/DHCR24
GOBP_SECONDARY_ALCOHOL_METABOLIC_PROCESS 114 0.7035005 2.459776 0.0000000 0.0000000 0.0000000 1161 MVD/HMGCS1/CYP51A1/PCSK9/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/TM7SF2/LIPC/ACLY/NSDHL/SQLE/SC5D/LDLR/MVK/NPC1/DISP3/LCAT/DHCR24/SCARB1/CYP46A1/PIP4P1/SCARF1/G6PD/ACADL/SREBF2/IDH1/FGF1/APOL1/APOBR/NFE2L1/PLPP6/APOL2/LIPE
GOBP_PROTEIN_DNA_COMPLEX_ASSEMBLY 165 -0.6276271 -2.434774 0.0000000 0.0000000 0.0000000 1304 CHAF1B/H3C1/H3C13/H3C10/H2BC11/H2BC3/HMGB2/H4C13/CENPP/H2BC7/HELLS/RAD51/CENPK/CDT1/CENPF/H2BC10/H4C1/OIP5/H3C7/H4C9/CENPE/H1-5/ASF1B/H3C12/H2BC17/H1-1/DLGAP5/H2BC13/DMC1/CDC45/H3C3/H2BC14/H3C8/H3C2/HJURP
GOBP_NUCLEAR_CHROMOSOME_SEGREGATION 250 -0.5946602 -2.421817 0.0000000 0.0000000 0.0000000 1339 RMI2/AXIN2/MAP10/RACGAP1/SYCP2/FBXO5/DSCC1/BRIP1/ANAPC4/CCNE1/MAD1L1/TRIP13/CCNB1/MAJIN/CDCA8/HASPIN/CENPK/KIF18A/PSRC1/ZWINT/PTTG1/KIF23/SGO2/CDT1/CENPF/SPC24/ESPL1/KIF14/FAM83D/CCNE2/TACC3/TTK/MAD2L1/SPAG5/KNL1/NDC80/PLK1/CENPE/NEK2/ESCO2/CDCA5/KIF4A/BUB1/DLGAP5/NUF2/KIF2C/DMC1/CDC20/NCAPH/KIFC1/SGO1/BUB1B/UBE2C/TOP2A/CEP55/NCAPG/SPC25/KIF18B
GOBP_MITOTIC_NUCLEAR_DIVISION 274 -0.5885897 -2.415452 0.0000000 0.0000000 0.0000000 861 ANAPC4/KIF11/AURKA/MAD1L1/TRIP13/CCNB1/CDCA8/HASPIN/CDC25C/CENPK/KIF18A/PSRC1/ZWINT/PTTG1/KIF23/SGO2/CDT1/CENPF/ESPL1/KIF14/KIF20B/TACC3/FBXO43/TTK/MAD2L1/KIF15/SPAG5/ANLN/NDC80/PLK1/CENPE/NEK2/CDCA5/KIF4A/TPX2/BUB1/DLGAP5/NUF2/KIF2C/CDCA2/CDC20/NCAPH/IGF1/KIFC1/SGO1/BUB1B/UBE2C/CEP55/NCAPG/KIF18B/MKI67/MYBL2
GOBP_STEROID_BIOSYNTHETIC_PROCESS 129 0.6771619 2.398071 0.0000000 0.0000000 0.0000000 1084 MVD/HMGCS1/CYP51A1/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/FGFR4/TM7SF2/ACLY/NSDHL/SQLE/STARD4/ERG28/SC5D/MVK/HSD17B12/DHCR24/SRD5A3/CYP46A1/HINT2/IL1A/G6PD/TNF/BMP6/PRLR/FGF1/BMP2/PLPP6
GOBP_STEROL_METABOLIC_PROCESS 116 0.6809713 2.378126 0.0000000 0.0000000 0.0000000 1161 MVD/HMGCS1/CYP51A1/PCSK9/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/TM7SF2/LIPC/ACLY/NSDHL/SQLE/ERG28/SC5D/LDLR/MVK/NPC1/DISP3/LCAT/DHCR24/SCARB1/CYP46A1/PIP4P1/CYP26B1/LIPA/SCARF1/G6PD/ACADL/SREBF2/FGF1/APOL1/APOBR/NFE2L1/PLPP6/APOL2/LIPE
GOBP_ALCOHOL_BIOSYNTHETIC_PROCESS 108 0.6730936 2.333432 0.0000000 0.0000000 0.0000000 1777 MVD/HMGCS1/CYP51A1/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/TM7SF2/ACLY/NSDHL/SC5D/MVK/FGF2/SNCA/DHCR24/SRD5A3/G6PD/BMP6/PCK2/FGF1/BMP2/PLPP6/PTAFR/GCH1/SPTSSA/PGP/ITPKC/GFI1/ACER2/NPC1L1/SPHK1/DAB2/CFTR
GOBP_DNA_CONFORMATION_CHANGE 300 -0.5574457 -2.321438 0.0000000 0.0000000 0.0000000 1109 DSCC1/H3C13/H3C10/EZH2/GINS1/MCMDC2/H2BC11/BRIP1/GPER1/H2BC3/HMGB2/H4C13/CENPP/BLM/H2BC7/HELLS/DNA2/RAD51/RECQL4/GINS2/CHD1L/H2BC10/H4C1/OIP5/H3C7/POLQ/H4C9/CDK1/RAD54B/PLK1/RAD54L/CDCA5/H1-5/ASF1B/H3C12/H2BC17/H1-1/ERCC6L/H2BC13/NCAPH/CDC45/TOP2A/H3C3/H2BC14/NCAPG/H3C8/H3C2/HJURP
GOBP_DNA_PACKAGING 206 -0.5727323 -2.296497 0.0000000 0.0000000 0.0000000 995 H3C10/EZH2/H2BC11/GPER1/H2BC3/HMGB2/H4C13/CENPP/H2BC7/HELLS/H2BC10/H4C1/OIP5/H3C7/H4C9/CDK1/PLK1/CDCA5/H1-5/ASF1B/H3C12/H2BC17/H1-1/H2BC13/NCAPH/TOP2A/H3C3/H2BC14/NCAPG/H3C8/H3C2/HJURP
GOBP_SPINDLE_ORGANIZATION 184 -0.5658778 -2.242132 0.0000000 0.0000000 0.0000000 1641 MAPK15/CENPJ/STARD9/WDR62/EFHC1/MAP10/RACGAP1/FBXO5/STMN1/KIF11/AURKA/CCNB1/PSRC1/KIF23/ESPL1/TACC3/GOLGA8M/TTK/KIF15/SPAG5/NDC80/PLK1/CENPE/NEK2/CCNB2/KIF4A/TPX2/DLGAP5/NUF2/GOLGA8H/CDC20/KIFC1/ASPM/SPC25/MYBL2
GOBP_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION 211 -0.5528624 -2.214685 0.0000000 0.0000000 0.0000000 754 H2BC11/H2BC3/HMGB2/H4C13/CENPP/H2BC7/HELLS/RAD51/CENPK/CDT1/CENPF/H2BC10/H4C1/OIP5/H3C7/H4C9/CENPE/H1-5/ASF1B/H3C12/H2BC17/H1-1/DLGAP5/H2BC13/DMC1/CDC45/H3C3/H2BC14/H3C8/H3C2/HJURP
GOBP_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS 179 0.5891830 2.179669 0.0000000 0.0000000 0.0000000 1777 MVD/HMGCS1/CYP51A1/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/FGFR4/TM7SF2/ACLY/NSDHL/SQLE/STARD4/ERG28/SC5D/MVK/FGF2/SNCA/SLC7A11/DHCR24/SRD5A3/PSAT1/CYP46A1/G6PD/TNF/BMP6/TPH2/PCK2/FGF1/BMP2/ZEB2/PLPP6/TGFB2/PTAFR/GCH1/SPTSSA/PGP/OPN3/PDXK/ITPKC/GFI1/KL/ACER2/NPC1L1/SPHK1/DAB2/CFTR
GOBP_DEFENSE_RESPONSE_TO_SYMBIONT 234 0.5692897 2.168335 0.0000000 0.0000000 0.0000000 2009 ZBP1/APOBEC3A/CXCL10/FGL2/IFIT2/MX2/ISG15/RSAD2/IFI44L/CXCL9/IFITM1/IFIT1/IFIT3/OAS3/OASL/ISG20/IFI6/MICA/OAS1/MX1/FOXP3/OAS2/IL1B/IFI27/BST2/NLRC5/IRF7/IFIH1/ZC3H12A/IL23A/PMAIP1/HERC5/BIRC3/APOBEC3B/IFITM3/MYD88/PML/PARP9/RIPK3/TICAM1/STAT1/IFIT5/GBP1/UNC13D/MICB/DTX3L/DDX60/TNFAIP3/TLR2/TRIM21/MLKL/IFNGR1/TRIM5/PLSCR1/EIF2AK2/MMP12/IFNLR1/STAT2/SHFL/IFI16/IRF9/DHX58/CD40/PTPN22/DDIT4/USP27X/ADAR/TRIM25/F2RL1
GOBP_RESPONSE_TO_VIRUS 312 0.5526251 2.165349 0.0000000 0.0000000 0.0000000 2707 ZBP1/APOBEC3A/CXCL10/HYAL1/FGL2/IFIT2/CCL22/MX2/CCL4/ISG15/RSAD2/IFI44L/CXCL9/IFITM1/IFIT1/IFIT3/OAS3/OASL/ISG20/IFI6/MICA/OAS1/MX1/HYAL3/CCL5/BATF3/FOXP3/OAS2/IL1B/IFI27/BST2/NLRC5/IRF7/IFIH1/ZC3H12A/IL23A/PMAIP1/HERC5/BIRC3/APOBEC3B/IFITM3/MYD88/PML/PARP9/TNF/RIPK3/TICAM1/STAT1/IFIT5/MAPK11/GBP1/UNC13D/IKBKG/MICB/LGALS9/IKBKE/DTX3L/DDX60/TNFAIP3/IFI44/TLR2/NMI/TRIM21/MLKL/IFNGR1/TRIM5/PLSCR1/ITGB8/EIF2AK2/IRAK3/DUOX2/NPC2/MMP12/IFNLR1/STAT2/SHFL/IFI16/IRF9/DHX58/CD40/PTPN22/DDIT4/USP27X/ADAR/MST1R/TRIM25/F2RL1/POLR3D/ITGB6/POLR3B/IFITM2/SAP30BP/SPON2/BCL3/TRIM22/NLRP1/SRC/NPLOC4/FOSL1/AUP1/IL15/GBP3/HYAL2/MARCHF2/SLFN11/NFKB1/IRF1
GOBP_ORGANELLE_FISSION 425 -0.5059520 -2.164339 0.0000000 0.0000000 0.0000000 864 BRIP1/ANAPC4/KIF11/CCNE1/AURKA/MAD1L1/TRIP13/CCNB1/MAJIN/CDCA8/HASPIN/CDC25C/RAD51/CENPK/KIF18A/PSRC1/ZWINT/PTTG1/KIF23/SGO2/CDT1/RAD51AP1/CENPF/ESPL1/KIF14/KIF20B/CCNE2/TACC3/FBXO43/TTK/MAD2L1/KIF15/SPAG5/ANLN/NDC80/RAD54B/PLK1/CENPE/NEK2/CNTD1/RAD54L/CCNB2/CDCA5/KIF4A/TPX2/BUB1/DLGAP5/NUF2/KIF2C/CDCA2/DMC1/CDC20/NCAPH/IGF1/KIFC1/SGO1/BUB1B/UBE2C/TOP2A/CEP55/ASPM/NCAPG/KIF18B/MKI67/MYBL2
GOBP_STEROID_METABOLIC_PROCESS 235 0.5599055 2.133593 0.0000000 0.0000000 0.0000000 1096 APOC1/MVD/HMGCS1/CYP51A1/PCSK9/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/FGFR4/TM7SF2/LIPC/ACLY/NSDHL/SQLE/STARD4/ERG28/SC5D/LDLR/MVK/NPC1/HSD17B12/DISP3/LCAT/DHCR24/SRD5A3/SCARB1/CYP46A1/HINT2/PIP4P1/CYP3A5/CYP26B1/LIPA/SCARF1/IL1A/G6PD/TNF/BMP6/ACADL/SREBF2/PRLR/FGF1/APOL1/BMP2/APOBR/NFE2L1/PLPP6/APOL2
GOBP_CYTOKINE_MEDIATED_SIGNALING_PATHWAY 339 0.5375923 2.123421 0.0000000 0.0000000 0.0000000 2527 ZBP1/CXCL10/CXCL11/CCL22/EBI3/CD70/IL36G/CCL4/ISG15/IL17REL/CXCL9/CCL20/IFITM1/CCR3/SLIT2/OAS3/OASL/CXCL2/CXCL6/CXCL3/ACSL1/CXCL8/OAS1/MX1/IL2RG/EREG/IL1R2/CCL5/CLCF1/CXCL5/OAS2/IL1RL1/IL1B/IFI27/NLRC5/IL1RAPL2/CXCL1/LRP8/IRF7/CEACAM1/BIRC3/IRAK2/CSF3/EDN1/USP18/PF4V1/IL31RA/IFITM3/MYD88/TNFSF13B/IL1RN/IL1A/CX3CL1/SOCS1/PARP9/IL1RL2/TNFRSF13C/TNF/TNFRSF1B/STAT1/NFKBIA/PRLR/IKBKE/OSMR/TNFAIP3/NMI/PDGFB/IL18R1/IFNGR1/TNIP2/ADIPOR2/PARP14/SH2B3/PTPRJ/OXSR1/IRAK3/IL34/IL36A/DUOX2/CSF1/TRAF1/ST18/CSNK2B/MMP12/GFI1/IL15RA/PALM3/IFNLR1/CCL17/STAT2/SPHK1/SP100/KRT18/IL7R/RFFL/IRAK1/USP27X/ADAR/MST1R/MAPK3/PLP2/PTPN2/F2RL1/PXDN/SYK/ADAM17/IFITM2/ILK/RIPK2/TRAF2/CCRL2/TMSB4X/SRC/STAT5A/GPS2/IL13RA1/IL4R/FAS/TYK2/IL17RD/EGR1/F3
GOBP_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS 437 0.5187376 2.083370 0.0000000 0.0000000 0.0000000 2220 PLA2G3/APOC1/MVD/HMGCS1/CYP51A1/FADS2/ELOVL6/EBP/DHCR7/LSS/FDPS/MSMO1/FADS1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/FGFR4/TM7SF2/LIPC/ACLY/LIPG/NSDHL/SCD/MLXIPL/STARD4/SC5D/IDO1/FASN/TRIB3/MVK/ALOXE3/FGF2/SNCA/TBXAS1/HSD17B12/SLC25A1/GGT7/KYNU/NT5E/IL1B/DHCR24/KMO/SRD5A3/PSAT1/PTGS2/CEACAM1/CYP46A1/ELOVL5/GGT5/EDN1/AACS/ELOVL7/ATF3/FA2H/G6PD/TNF/BMP6/ACADL/ACACA/PCK2/PYCR1/ACSS3/FGF1/BMP2/CYP4A22/BCO1/LIPH/MTHFR/PGD/ALDH1A3/PLPP6/TPK1/PTGES/MTHFD1L/ATF4/PTAFR/ASS1/GCH1/SPTSSA/PGP/PLOD3/CBS/ELOVL1/SELENOS/HAAO/PDXK/ITPKC/NLN/UCKL1/GFI1/ACER2/NPC1L1/HSD17B8/SPHK1/DAB2/C1QTNF3/CFTR/PPARGC1A/ASL/SESN2/ACOT7/BCAT1/HRH1/HACD2/ANXA1/PTPN2/GLUD1/DHDDS/PTGES2/PNP/SYK/QDPR/GOT1/ALDH1A2/ELOVL4/ACAA2/GPT/CTH
GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS 302 0.5250369 2.047272 0.0000000 0.0000000 0.0000000 2699 PLA2G3/ZBP1/S100A7/CXCL10/CCL4/LDLR/IDO1/S100A12/SLIT2/OASL/NTRK3/CXCL8/FGF2/SNCA/KDR/EREG/CCL5/LBP/IL1RL1/IL1B/NLRC5/IRF7/THBS1/IL23A/PTGS2/CNR1/SH2D1B/EDN1/FYN/IFI35/SERPINE1/ADAM8/GBP5/CXCL17/SCARF1/EMILIN2/CX3CL1/KLK7/PARP9/TNIP1/S100A8/TNF/BMP6/STX3/VEGFA/LAG3/LGALS1/NFKBIA/CD47/ARTN/LGALS9/IKBKE/LY96/OSMR/DDX60/FKBP1B/TLR2/NMI/PDGFB/RAET1E/TRIM5/TLR4/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/S100A9/OXSR1/RARRES2/CAMK2N1/MET/C2CD4A/IL34/CSF1/STX4/OPTN/LYN/NFKBIZ/CADM1/MMP12/TNFSF14/LGMN/NOD2/ETS1/IFI16/AKIRIN2/DHX58/HLA-E/SCG2/USP27X/CCN4/MAPK3/F2RL1/SERPINF2/MOSPD2/TPBG/RNF31/SYK/ADAM17/POLR3D/P2RX4/POLR3B/DAPK2/RIPK2/FLNA/TMSB4X/NLRP1/SRC/NOD1/F3/CASP6/IL15/S100A14/NECTIN2/HYAL2/NDEL1/CTSC/TRADD/SWAP70/CEBPB
GOBP_ALCOHOL_METABOLIC_PROCESS 283 0.5304847 2.046629 0.0000000 0.0000000 0.0000000 1787 MVD/HMGCS1/CYP51A1/PCSK9/EBP/ACSS2/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/TM7SF2/LIPC/ACLY/NSDHL/SQLE/SC5D/LDLR/MVK/FGF2/RDH11/NPC1/SNCA/DISP3/LCAT/DHCR24/SRD5A3/NUDT10/SCARB1/CYP46A1/ALDH3B2/NUDT11/PIP4P1/CYP3A5/SCARF1/GALR2/G6PD/BMP6/ACADL/SDR16C5/SREBF2/PCK2/IDH1/FGF1/APOL1/BMP2/BCO1/APOBR/NFE2L1/ALDH1A3/PLPP6/TPK1/APOL2/LIPE/PTAFR/GDPD3/GCH1/RETSAT/SPTSSA/PGP/CYP1B1/NPC2/ITPKC/GFI1/GALK1/ALDH1B1/ACER2/NPC1L1/SPHK1/DAB2/DHRS7/PLPP3/CFTR/ITPK1
GOBP_TAXIS 433 0.4837620 1.942205 0.0000000 0.0000000 0.0000000 2640 NTRK1/DEFB4A/S100A7/TNFAIP6/CXCL10/CXCL11/PAX6/CCL22/CCL4/TUBB3/CXCL9/CCL20/S100A12/CCR3/PLAUR/SLIT2/CXCL2/DPYSL2/CXCL6/NR4A1/CXCL3/NTRK3/L1CAM/CXCL8/FGF2/KDR/CCL5/LBP/DRAXIN/CXCL5/IL1B/DEFB1/SEMA3B/ITGA9/VCAM1/CXCL1/SCN1B/CCN3/RELN/CMTM3/PLAU/THBS1/IL23A/C5AR2/SEMA3D/EDN1/FYN/EPHA10/EGR2/PF4V1/TYMP/FEZ1/SERPINE1/ADAM8/CXCL17/EPHA3/SEMA7A/CX3CL1/S100A8/CXCL16/STX3/VEGFA/NRXN3/COLEC10/LAMA3/HBEGF/LAMC2/ADGRE2/FGF1/ARTN/LGALS9/SAA1/KLF7/PDGFB/PTPRO/TGFB2/PTAFR/ECE1/CCN1/PRKCQ/PTPRJ/GREM1/S100A9/PLXNA3/OXSR1/RARRES2/DUSP3/MET/IL34/FLRT2/CSF1/NRCAM/STX4/LYN/FLT1/ITGB3/TNFSF14/KIF5C/LGMN/CCL17/SLC8B1/NOD2/PIK3C2G/EFNA5/ISL1/RHOG/DUSP1/SCG2/HRH1/MAPK3/PLP2/ANXA1/PTPN2/F2RL1/PLXNA1/TRIO/MOSPD2/ITGAV/TPBG/NIBAN2/TRPM4/SYK/ADAM17/P2RX4/USP14/EPHB4/PLXNA4/RALA/BCAR1/DAPK2/TREM1/CCRL2/SLC12A2/TMSB4X/NTN1/SEMA3A/FOSL1/MAP2K1/ROBO2/F3/NRG1/VASP/CMTM7/SEMA3C/EPHA2/S100A14
GOBP_CILIUM_ORGANIZATION 375 -0.4576607 -1.936291 0.0000000 0.0000000 0.0000000 3908 RSPH4A/CEP126/ATP6V1D/CFAP298/TOGARAM1/TBC1D15/STK36/UNC119B/BBS12/ARL6/ARL13B/IQCB1/SPEF1/CELSR2/TUB/CPLANE1/ARL3/TMEM216/WDR19/CLCN4/BBS4/DYNLL1/CFAP20/DNAAF5/RABL2B/DNAI3/TMEM138/CEP41/BBIP1/CEP250/DRC1/CFAP126/CCDC57/CCDC96/INTU/TBC1D19/TRAF3IP1/SPAG6/TCTN2/IFT74/DNAAF10/CFAP100/CEP135/DYNC2I1/PIBF1/ZMYND10/ODAD4/SSX2IP/LRGUK/CFAP91/WDPCP/ARMC2/TTC29/DZIP1L/TBC1D32/VDAC3/BBS9/FOXJ1/B9D1/DNAAF11/DNAAF3/TMEM237/ARMC9/KIF27/BBOF1/CFAP47/DYNLT2B/IFT43/TBC1D8/CFAP46/SPATA6/TCTN1/MKS1/HOATZ/TTLL3/CEP290/BBS2/CFAP69/DNAAF4/DNAL1/KIF24/CBY1/DYNC2LI1/CEP162/CFAP58/CCDC66/ENO4/IFT52/CCDC113/ODAD1/CEP19/IFT122/IFT140/CEP97/CCDC40/CEP164/CCDC88A/DNAJB13/CFAP52/IFT57/FUZ/NEK1/CFAP54/RSPH9/RPGRIP1L/DRC7/B9D2/IFT27/ODAD3/CATIP/WDR35/SPAG17/DZIP1/CFAP73/CFAP157/NME5/SAXO1/ODF2L/CLUAP1/PCM1/IFT88/LCA5/CPLANE2/CC2D2A/DAW1/TTC12/WDR90/CEP120/DNAI1/IFT81/RSPH1/DNAH7/TMEM67/IQCG/RFX2/RPGR/CIBAR1/UBXN10/SPEF2/CCP110/CCDC39/CEP83/SPAG16/KCTD17/IFT172/CFAP61/KIF19/IFT80/TEKT3/CDKL1/MAPK15/ROPN1B/CCDC65/HYDIN/CENPJ/CFAP206/TEKT2/LRRC49/TEKT1/RFX3/TTC21A/CDC14A/DNAI4/CFAP65/DYNC2H1/FBF1/NOTCH1/GMNC/TTC21B/DNAI2/CIBAR2/MPHOSPH9/CFAP74/CFAP44/TEKT4/MNS1/TEKT5/DNAAF8/CEP78/DNAH1/DNAH5/CFAP70/CFAP43/IQUB/CFAP221/ODAD2/LCA5L/MCIDAS/DNAAF6/RP1/DNAAF1/CFAP161/CFAP53/CCDC13/DNAH2/HYLS1/CCNO/MEIG1/CROCC/POC1A/PLK4
GOBP_REGULATION_OF_DEFENSE_RESPONSE 445 0.4800072 1.935421 0.0000000 0.0000000 0.0000000 3036 PLA2G3/ZBP1/TNFAIP6/FGL2/ISG15/LDLR/IDO1/S100A12/IFIT1/MVK/OAS3/CXCL6/MICA/OAS1/NCF1/SNCA/EREG/CCL5/LBP/FOXP3/NT5E/IL1RL1/IL1B/NLRC5/CCN3/LRP8/IRF7/ZC3H12A/IL23A/PTGS2/CNR1/CEACAM1/SH2D1B/HERC5/BIRC3/FYN/USP18/IFI35/SERPINE1/DUOXA2/ADAM8/GBP5/MYD88/CXCL17/SEMA7A/EMILIN2/CX3CL1/SOCS1/KLK7/PARP9/TNIP1/S100A8/IL1RL2/TNF/TNFRSF1B/LAG3/STAT1/LGALS1/NFKBIA/FANCA/SOCS3/CD47/MICB/LGALS9/SAA1/IKBKE/DTX3L/OSMR/SERPINB4/TNFAIP3/SERPINB9/TLR2/NMI/TRIM21/RAET1E/PTGES/MEF2C/TRIM5/TLR4/PARP14/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/S100A9/KLF4/DUSP10/RHBDF2/CAMK2N1/IRAK3/PSMA6/SELENOS/C2CD4A/OPTN/TYRO3/LYN/NFKBIZ/CADM1/CD200/MMP12/ACE2/ARG2/IFNLR1/STAT2/NOD2/SPHK1/ETS1/FNDC4/IFI16/C1QTNF3/N4BP1/AKIRIN2/DUOXA1/DHX58/HLA-E/ISL1/PTPN22/TRAFD1/USP27X/CCN4/ADAR/SBNO2/MAPK3/ANXA1/PTPN2/F2RL1/METRNL/RNF31/SYK/POLR3D/FURIN/MAPK7/POLR3B/HLA-B/CASP5/RIPK2/TMSB4X/NLRP1/SRC/NPLOC4/GPS2/SMPDL3B/NOD1/ZFP36/CASP6/IL15/LACC1/NECTIN2/HYAL2/CTSC/IL1R1/TRADD/CEBPB/NFKB1/IRF1/MFHAS1/IL18/RHBDD3/FAM3A/C3/ZNFX1/FADD/SLC15A4/CASP8/PLCG1/GPSM3/TIRAP/HLA-A/PTPN11
GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 265 0.5316802 2.044045 0.0000000 0.0000000 0.0000000 3036 ZBP1/FGL2/ISG15/IFIT1/OAS3/OASL/CXCL6/MICA/OAS1/NCF1/EREG/CCL5/LBP/FOXP3/IL1B/NLRC5/LRP8/IRF7/ZC3H12A/IL23A/CEACAM1/SH2D1B/HERC5/BIRC3/FYN/USP18/IFI35/IL4I1/ADAM8/GBP5/EMILIN2/CX3CL1/SOCS1/KLK7/PARP9/BMP6/LAG3/STAT1/CD55/MICB/CD274/LGALS9/IKBKE/DTX3L/LY96/SERPINB4/DDX60/TNFAIP3/SERPINB9/NMI/TRIM21/RAET1E/TRIM5/TLR4/PARP14/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/DUSP10/IRAK3/OPTN/TYRO3/LYN/TRIB1/CADM1/MMP12/ARG2/IFNLR1/STAT2/NOD2/IFI16/N4BP1/AKIRIN2/DHX58/HLA-E/PTPN22/TRAFD1/USP27X/ADAR/MAPK3/PTPN2/F2RL1/RNF31/SYK/POLR3D/POLR3B/HLA-B/RIPK2/SRC/NPLOC4/NOD1/AHR/CASP6/IL15/NECTIN2/TIGAR/IRF1/FAM3A/ZNFX1/FADD/SLC15A4/CASP8/TIRAP/HLA-A/PTPN11
GOBP_RESPONSE_TO_BACTERIUM 422 0.4690294 1.878147 0.0000000 0.0000000 0.0000000 3033 DEFB4A/S100A7/CXCL10/CXCL11/IL36G/ISG15/CXCL9/IDO1/CCL20/CMPK2/S100A12/OAS3/CXCL2/TNIP3/CXCL6/NR4A1/CXCL3/C15orf48/CXCL8/MICA/OAS1/SNCA/ALPL/PI3/CCL5/LBP/FOXP3/CXCL5/OAS2/IL1B/DEFB1/KMO/VCAM1/HP/CXCL1/HERC6/ZC3H12A/IL23A/PTGS2/CNR1/SCARB1/ADAMTS5/IRAK2/CSF3/PGLYRP4/EDN1/PF4V1/FOS/SERPINE1/ARID5A/GBP5/MYD88/GBP2/ANKRD1/EMILIN2/IL1A/ANXA3/CX3CL1/KLK7/TNIP1/S100A8/TNF/BMP6/TNFRSF1B/TICAM1/CD55/NFKBIA/NOS2/PRLR/PCK2/CD274/BMP2/LGALS9/PGLYRP3/LY96/C4BPA/TNFAIP3/IFI44/TLR2/MEF2C/FAM20A/TRIM5/TLR4/PTAFR/TNIP2/ASS1/JUND/RNF213/GCH1/S100A9/ADAMTS9/DUSP10/ADAM9/RARRES2/IRAK3/SELENOS/IL36A/OPTN/LYN/AKAP12/TRIB1/LDOC1/GFI1/LCN2/ARG2/SELP/PALM3/NOD2/H2BC21/PELI1/AKIRIN2/NOCT/BCL10/DHX58/IL7R/GBP4/HLA-E/ADGRB1/IRAK1/PTPN22/VIM/SBNO2/MAPK3/BPIFA2/F2RL1/KRT6A/WFDC3/RNF31/SYK/ADAM17/HLA-B/SMAD6/SPON2/BCL3/RIPK2/TREM1/CAPN2/NLRP1/SRC/MALT1/RNASE7/TENT5A/NOD1/PLAA/RBCK1/LRG1/ZFP36/CLDN1/CD86/AKAP8/EPHA2/S100A14/MARCHF2/CEBPB/MAP2K3/NFKB1/NFKBIB/C2/IL18/C3/ZNFX1/DAB2IP/MAPKAPK2/OCIAD2/CNP/GJB6/CASP8/LYG1/TIRAP/HLA-A
GOBP_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY 193 -0.5406367 -2.162582 0.0000000 0.0000001 0.0000001 3197 H2BC18/H1-2/H4C2/CENPW/H2AX/NAP1L1/H3C6/HIRIP3/H2BC6/HDAC8/H4C6/CHD3/NASP/SMYD3/L3MBTL1/PHF8/H2BC15/H2BC9/SMARCD3/H3-3A/SMARCE1/M1AP/H3C11/H4C12/MIS18A/H2BC12/H4C4/ATF7IP2/CHAF1B/H3C1/H3C13/H3C10/EZH2/H2BC11/H2BC3/HMGB2/H4C13/CENPP/H2BC7/HELLS/H2BC10/H4C1/OIP5/H3C7/H4C9/H1-5/ASF1B/H3C12/H2BC17/H1-1/H2BC13/H3C3/H2BC14/H3C8/H3C2/HJURP
GOBP_MITOTIC_SPINDLE_ORGANIZATION 122 -0.6118388 -2.278049 0.0000000 0.0000001 0.0000001 1470 WDR62/EFHC1/MAP10/RACGAP1/STMN1/KIF11/AURKA/CCNB1/PSRC1/KIF23/TACC3/TTK/KIF15/NDC80/PLK1/CENPE/NEK2/KIF4A/TPX2/DLGAP5/NUF2/CDC20/KIFC1/SPC25/MYBL2
GOBP_NUCLEOSOME_ORGANIZATION 139 -0.5828114 -2.209606 0.0000000 0.0000001 0.0000001 1304 CHAF1B/H3C1/H3C13/H3C10/H2BC11/H2BC3/HMGB2/H4C13/CENPP/H2BC7/H2BC10/H4C1/OIP5/H3C7/H4C9/H1-5/ASF1B/H3C12/H2BC17/H1-1/H2BC13/H3C3/H2BC14/H3C8/H3C2/HJURP
GOBP_CELL_CHEMOTAXIS 213 0.5468685 2.060977 0.0000000 0.0000001 0.0000001 2343 DEFB4A/S100A7/TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/CCR3/SLIT2/CXCL2/CXCL6/NR4A1/CXCL3/CXCL8/FGF2/KDR/CCL5/LBP/CXCL5/IL1B/ITGA9/VCAM1/CXCL1/CCN3/THBS1/IL23A/C5AR2/EDN1/PF4V1/SERPINE1/ADAM8/CXCL17/CX3CL1/S100A8/CXCL16/VEGFA/HBEGF/ADGRE2/FGF1/LGALS9/SAA1/PDGFB/PTPRO/TGFB2/PRKCQ/GREM1/S100A9/OXSR1/RARRES2/MET/IL34/CSF1/LYN/FLT1/TNFSF14/LGMN/CCL17/SLC8B1/NOD2/RHOG/DUSP1/SCG2/HRH1/MAPK3/ANXA1/F2RL1/MOSPD2/TPBG/TRPM4/SYK/ADAM17/P2RX4/BCAR1/DAPK2/TREM1/CCRL2/SLC12A2/TMSB4X
GOBP_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE 357 0.4766531 1.890826 0.0000000 0.0000001 0.0000001 3034 PLA2G3/ZBP1/THEMIS2/RSAD2/IDO1/HMSD/ITGAM/LAT2/EREG/CCL5/CLCF1/LBP/FOXP3/IL1B/NLRC5/CMTM3/IRF7/ZC3H12A/IL23A/CNR1/CEACAM1/SH2D1B/C5AR2/CD177/NR4A3/FYN/PLPP4/IFI35/ADAM8/ARID5A/GBP5/TNFSF13B/KLK7/PARP9/TNF/COLEC10/LAG3/CARD11/CD55/STXBP1/GBP1/RFTN1/IKBKG/CD47/MICB/CD274/CFB/LGALS9/IKBKE/C4BPA/UBASH3A/NMI/RAET1E/TGFB2/IL18R1/MEF2C/TRIM5/TLR4/PTAFR/CLEC7A/HLA-G/KLRD1/PLSCR1/C1S/PRKCQ/HLA-F/PVR/PTPRJ/DUSP3/CD276/STX4/CD46/LYN/NFKBIZ/CADM1/MMP12/BTN3A1/NFKBID/GAB2/NOD2/IFI16/AKIRIN2/BCL10/CD40/HLA-E/PTPN22/USP27X/ANXA1/PTPN2/F2RL1/SHLD1/RNF31/THY1/SYK/C8B/POLR3D/SHLD2/POLR3B/HLA-B/BCAR1/RIPK2/TRAF2/SRC/MALT1/PRKCH/GPS2/IL4R/LPXN/RBCK1/TFRC/CASP6/CD86/IL15/NECTIN2/IL1R1/C2/IL18/C3/ZNFX1/SHLD3/FADD/SLC15A4/PLA2G4A/PLCG1/TIRAP/HLA-A/BTN2A2
GOBP_LEUKOCYTE_DIFFERENTIATION 404 0.4626330 1.850200 0.0000000 0.0000002 0.0000002 2708 PLA2G3/NTRK1/TNFAIP6/MT1G/FGL2/FZD9/RSAD2/DLL4/FASN/TNFSF9/LIF/EVI2B/BATF3/CLCF1/BATF2/FOXP3/KLF6/IL1B/VCAM1/HDAC9/IRF7/ZC3H12A/IL23A/CEACAM1/LRRC17/CSF3/IKZF1/IL31RA/RELB/FOS/PRXL2A/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/TNF/FAM20C/VEGFA/LAG3/RIPK3/CARD11/LGALS1/GPR68/VNN1/FANCA/JUN/BATF/UBD/LGALS9/FSTL3/PRDM1/TLR2/IL18R1/TLR4/DOCK10/HLA-G/RRAS/GLO1/LRRC8A/PTPRJ/IL11/ITGB8/INHBA/DUSP10/DNAJB9/TFE3/MYC/IL34/CSF1/CD46/TYRO3/LYN/NFKBIZ/TRIB1/PPARGC1B/IL15RA/NFKBID/GAB2/IFI16/SOX4/CTNNBIP1/TMEM176A/IL7R/KLF10/PTPN22/TOX/CCN4/SBNO2/SRF/ZEB1/ANXA1/PTPN2/F2RL1/PRELID1/PNP/SYK/ADAM17/ITGB6/CEBPG/MMP14/TMEM176B/HLA-B/BCL3/RIPK2/SRC/MALT1/GPS2/ST3GAL1/IL4R/EGR1/NFIL3/BAK1/TFRC/JUNB/CMTM7/CD86/IL15/EPHA2/ZBTB46/CEBPB/IRF1/WNT4
GOBP_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS 421 0.4560574 1.824662 0.0000000 0.0000004 0.0000003 1787 MVD/HMGCS1/CYP51A1/PCSK9/EBP/ACSS2/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/FGFR4/TM7SF2/LIPC/ACLY/NSDHL/SQLE/STARD4/ERG28/SC5D/LDLR/MVK/FGF2/RDH11/NPC1/ITGAM/SNCA/SLC7A11/ALPL/DISP3/LCAT/DHCR24/SRD5A3/PSAT1/NUDT10/SCARB1/CYP46A1/ALDH3B2/NUDT11/PIP4P1/DUOXA2/CYP3A5/CYP26B1/LIPA/SCARF1/GALR2/G6PD/TNF/BMP6/ACADL/SDR16C5/SREBF2/TPH2/PCK2/IDH1/FGF1/APOL1/BMP2/BCO1/APOBR/ZEB2/NFE2L1/ALDH1A3/PLPP6/TPK1/APOL2/TGFB2/LIPE/PTAFR/GDPD3/GCH1/RETSAT/SPTSSA/PGP/PAX8/CYP1B1/DUOX2/OPN3/NPC2/PDXK/ITPKC/GFI1/KL/GALK1/ALDH1B1/ACER2/LGMN/NPC1L1/SPHK1/DAB2/DHRS7/PLPP3/CFTR/ITPK1
GOBP_PHOSPHOLIPID_METABOLIC_PROCESS 328 0.4795588 1.889764 0.0000000 0.0000005 0.0000004 1340 PLA2G3/PNPLA3/APOC1/MVD/HMGCS1/PCSK9/FDPS/FADS1/IDI1/FDFT1/LIPC/LIPG/LPIN1/LDLR/MVK/PLA2G4C/FGF2/SNCA/LCAT/SRD5A3/GPCPD1/SCARB1/SOCS2/PLPP4/PIP4P1/ABHD4/MFSD2A/GALR2/PCYT2/SOCS1/SELENOI/TMEM86B/ENPP6/IDH1/SOCS3/LIPH/MTMR11/PLPP6/PI4K2A/PDGFB/PISD/GDPD3/PLSCR1/GPAT3/PLAAT1/PIGW/CHP1/PGP
GOBP_GRANULOCYTE_MIGRATION 106 0.6307265 2.171695 0.0000000 0.0000006 0.0000005 2300 S100A7/TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/ITGA9/CXCL1/THBS1/IL23A/C5AR2/CD177/OLFM4/EDN1/PECAM1/PF4V1/ADAM8/MYD88/CXCL17/IL1A/CX3CL1/S100A8/ADGRE2/SAA1/TGFB2/S100A9/RARRES2/IL34/CSF1/CCL17/NOD2/RHOG/SCG2/HRH1/MAPK3/ANXA1/MOSPD2/SYK/XG/DAPK2/TREM1
GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE 199 0.5448398 2.031895 0.0000000 0.0000006 0.0000005 3025 PLA2G3/ZBP1/LDLR/IDO1/S100A12/SNCA/EREG/CCL5/LBP/IL1RL1/IL1B/NLRC5/IRF7/IL23A/PTGS2/CNR1/SH2D1B/FYN/IFI35/SERPINE1/ADAM8/GBP5/EMILIN2/CX3CL1/KLK7/PARP9/TNIP1/S100A8/TNF/LAG3/LGALS1/NFKBIA/CD47/IKBKE/OSMR/TLR2/NMI/RAET1E/MEF2C/TRIM5/TLR4/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/S100A9/CAMK2N1/C2CD4A/OPTN/LYN/NFKBIZ/CADM1/MMP12/NOD2/ETS1/IFI16/AKIRIN2/HLA-E/USP27X/CCN4/MAPK3/F2RL1/RNF31/SYK/POLR3D/POLR3B/RIPK2/NLRP1/SRC/NOD1/CASP6/IL15/NECTIN2/HYAL2/CTSC/TRADD/CEBPB/IL18/C3/ZNFX1/FADD/SLC15A4/GPSM3/TIRAP
GOBP_LEUKOCYTE_MIGRATION 269 0.4974957 1.915816 0.0000000 0.0000006 0.0000005 2361 S100A7/TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/SELL/CCL5/LBP/CXCL5/IL1B/ITGA9/VCAM1/CXCL1/CCN3/THBS1/IL23A/C5AR2/CD177/OLFM4/EDN1/FYN/PECAM1/PF4V1/SERPINE1/ADAM8/MYD88/CD34/CXCL17/IL1A/CX3CL1/S100A8/ASB2/TNF/CXCL16/VEGFA/RIPK3/ADGRE2/CD47/ARTN/LGALS9/SAA1/STK10/PDGFB/SPNS2/PTPRO/TGFB2/PTAFR/ICAM1/GREM1/S100A9/OXSR1/RARRES2/MSN/ADTRP/IL34/CSF1/LYN/CD200/FLT1/TNFSF14/SELP/LGMN/CCL17/SLC8B1/NOD2/RHOG/DUSP1/SCG2/ITGB7/HRH1/MAPK3/ANXA1/F2RL1/MOSPD2/TRPM4/THY1/SYK/ADAM17/CD9/XG/MMP14/P2RX4/HMOX1/DAPK2/TREM1/SLC12A2/ITGA3/SRC
GOBP_CHROMATIN_REMODELING 226 -0.4965652 -1.997307 0.0000000 0.0000006 0.0000005 1304 CHAF1B/H3C1/H3C13/H3C10/H2BC11/MYB/H2BC3/HMGB2/H4C13/CENPP/H2BC7/HELLS/CHD1L/H2BC10/H4C1/OIP5/H3C7/H4C9/H1-5/ASF1B/H3C12/H2BC17/H1-1/H2BC13/H3C3/H2BC14/H3C8/H3C2/HJURP
GOBP_POSITIVE_REGULATION_OF_LOCOMOTION 456 0.4403084 1.779112 0.0000000 0.0000008 0.0000007 3181 S100A7/TNFAIP6/CXCL10/HYAL1/CCL4/FGFBP1/CCL20/SLIT2/SLC8A1/NTRK3/CXCL8/FGF2/MIR200A/KDR/CCL5/LBP/IL1B/DEFB1/TMSB15B/SEMA3B/RELN/HDAC9/PLAU/THBS1/ZC3H12A/IL23A/PTGS2/SCARB1/SEMA3D/NR4A3/EDN1/FOXC2/PECAM1/SERPINE1/DUOXA2/ADAM8/CXCL17/SEMA7A/IL1A/ANXA3/CX3CL1/TNF/CEACAM6/CXCL16/STX3/RHOB/VEGFA/HBEGF/LAMC2/SOX9/JUN/CLDN4/CD47/FGF1/CD274/HDAC6/ARTN/BMP2/LGALS9/NEDD9/PDGFB/TGFB2/TLR4/PTAFR/ICAM1/CCN1/CLEC7A/RRAS/DAPK3/OXSR1/FERMT1/PODXL/ADAM9/RARRES2/ATOH8/MET/MYC/IL34/CYP1B1/EGF/DUOX2/CSF1/STX4/LYN/AKAP12/MMP7/FLT1/ITGB3/WNT7A/IRS2/TNFSF14/COL1A1/SELP/CD151/LGMN/SPHK1/DAB2/ETS1/PLPP3/MYO1C/AKT3/RIPOR1/CD40/SHTN1/SCG2/CCN4/PDGFC/MAPK3/ANXA1/F2RL1/TJP1/MOSPD2/ITGAV/TPBG/CAVIN1/THY1/ADAM17/HDAC7/XG/MMP14/P2RX4/SPAG9/ADAMTS1/HMOX1/MAP4K4/BCAR1/DAPK2/ITGA3/TMSB4X/TGFBR1/SRC/NTN1/RHOD/RHOC/SEMA3A/STAT5A/PLAA/F3/MAPRE2/CLDN1/DIAPH1/SYDE1/SEMA3C/EPHA2/S100A14/IL1R1/SUN2/MAP3K3/TRADD/SWAP70/MAP2K3/ACTG1/PIK3C2A/DOCK5/RTN4/DAB2IP/FADD/FAM83H/ITGA6/SRPX2/MYADM/NSMF/PLCG1/GPSM3/TIRAP/ITGA5/SPARC/TGFBR2/MGAT5/RRAS2/GFUS/DDRGK1/MCU/SUCNR1/TWIST1/PDPN/ACTA2/CAV1
GOBP_MYELOID_LEUKOCYTE_MIGRATION 159 0.5651661 2.048546 0.0000000 0.0000011 0.0000009 2164 S100A7/TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/ITGA9/CXCL1/CCN3/THBS1/IL23A/C5AR2/CD177/OLFM4/EDN1/PECAM1/PF4V1/SERPINE1/ADAM8/MYD88/CXCL17/IL1A/CX3CL1/S100A8/VEGFA/ADGRE2/CD47/SAA1/PDGFB/PTPRO/TGFB2/GREM1/S100A9/RARRES2/IL34/CSF1/LYN/CD200/FLT1/LGMN/CCL17/NOD2/RHOG/DUSP1/SCG2/HRH1/MAPK3/ANXA1/MOSPD2/SYK/CD9/XG/MMP14/P2RX4
GOBP_MITOTIC_METAPHASE_PLATE_CONGRESSION 52 -0.7230919 -2.332315 0.0000000 0.0000012 0.0000010 758 MAD1L1/CCNB1/CDCA8/KIF18A/PSRC1/CDT1/KIF14/NDC80/CENPE/CDCA5/NUF2/KIF2C/KIFC1/CEP55
GOBP_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS 145 -0.5598493 -2.141243 0.0000000 0.0000013 0.0000010 1470 WDR62/EFHC1/MAP10/RACGAP1/STMN1/KIF11/AURKA/CCNB1/PSRC1/KIF23/ESPL1/TACC3/TTK/MAD2L1/KIF15/NDC80/PLK1/CENPE/NEK2/KIF4A/TPX2/DLGAP5/NUF2/CDC20/KIFC1/SPC25/MYBL2
GOBP_LEUKOCYTE_CHEMOTAXIS 159 0.5632801 2.041710 0.0000000 0.0000013 0.0000010 2105 S100A7/TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/ITGA9/CXCL1/CCN3/THBS1/IL23A/C5AR2/EDN1/PF4V1/SERPINE1/ADAM8/CXCL17/CX3CL1/S100A8/CXCL16/VEGFA/ADGRE2/LGALS9/SAA1/PDGFB/PTPRO/TGFB2/GREM1/S100A9/OXSR1/RARRES2/IL34/CSF1/LYN/FLT1/TNFSF14/LGMN/CCL17/SLC8B1/NOD2/DUSP1/SCG2/HRH1/MAPK3/ANXA1/F2RL1/MOSPD2/TRPM4/SYK/ADAM17
GOBP_GRANULOCYTE_CHEMOTAXIS 89 0.6532290 2.187519 0.0000000 0.0000021 0.0000017 2098 S100A7/TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/ITGA9/CXCL1/THBS1/IL23A/C5AR2/EDN1/PF4V1/CXCL17/CX3CL1/S100A8/ADGRE2/SAA1/TGFB2/S100A9/RARRES2/IL34/CSF1/CCL17/NOD2/SCG2/HRH1/MAPK3/ANXA1/MOSPD2/SYK
GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS 77 0.6742157 2.202925 0.0000000 0.0000022 0.0000018 1780 APOBEC3A/ISG15/RSAD2/IFITM1/IFIT1/OAS3/OASL/ISG20/OAS1/MX1/CCL5/OAS2/BST2/IFIH1/APOBEC3B/IFITM3/TNIP1/TNF/TRIM31/STAT1/IFIT5/TRIM21/TRIM5/PLSCR1/TRIM14/EIF2AK2/SHFL/IFI16/N4BP1
GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE 170 0.5550075 2.041309 0.0000000 0.0000025 0.0000020 3036 ZBP1/ISG15/OAS3/MICA/OAS1/NCF1/EREG/CCL5/LBP/NLRC5/LRP8/IRF7/CEACAM1/SH2D1B/BIRC3/FYN/USP18/IFI35/ADAM8/GBP5/SOCS1/PARP9/LAG3/LGALS9/IKBKE/SERPINB4/TNFAIP3/SERPINB9/NMI/TRIM21/RAET1E/TRIM5/TLR4/PARP14/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/DUSP10/IRAK3/TYRO3/LYN/CADM1/MMP12/STAT2/NOD2/IFI16/N4BP1/AKIRIN2/DHX58/HLA-E/PTPN22/TRAFD1/USP27X/ADAR/PTPN2/SYK/POLR3D/POLR3B/HLA-B/SRC/CASP6/NECTIN2/IRF1/FAM3A/ZNFX1/FADD/SLC15A4/CASP8/TIRAP/HLA-A/PTPN11
GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 235 0.5075557 1.934108 0.0000000 0.0000029 0.0000023 2669 PLA2G3/FGL2/RSAD2/CXCL6/MICA/NCF1/ITGAM/CLCF1/LBP/FOXP3/IL1B/BST2/ZC3H12A/IL23A/CEACAM1/SH2D1B/CD177/NR4A3/CAMK4/IL4I1/ARID5A/SEMA7A/KLK7/TNF/TNFRSF1B/COLEC10/LAG3/RIPK3/TICAM1/CD55/NOS2/STXBP1/ADGRE2/UNC13D/CD47/LGALS9/C4BPA/SERPINB4/DDX60/SERPINB9/RAET1E/TGFB2/IL18R1/TLR4/PTAFR/ICAM1/CLEC7A/HLA-G/KLRD1/HLA-F/PVR/PTPRJ/DUSP10/DNAJB9/IRAK3/STX4/CD46/LYN/NFKBIZ/CADM1/NFKBID/GAB2/NOD2/BCL10/DHX58/CD40/IL7R/HLA-E/PTPN22/ANXA1/F2RL1/SHLD1/TRPM4/SYK/SHLD2/HLA-B/HMOX1/SPON2/RIPK2/TRAF2/MALT1/SLC7A5/IL4R/AHR/TFRC/CD86/LACC1/NECTIN2/IL1R1
GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION 344 0.4567902 1.803570 0.0000000 0.0000032 0.0000026 2707 PLA2G3/LUM/EBI3/ISG15/RSAD2/IDO1/OAS3/OAS1/EREG/LBP/SERPINB7/FOXP3/OAS2/IL1RL1/IL1B/IRF7/IFIH1/THBS1/IL23A/PTGS2/NOX1/NR4A3/NLRP2/CAMK4/SERPINE1/ADAM8/ARID5A/GBP5/MYD88/CD83/CD34/CXCL17/SEMA7A/IL1A/CX3CL1/IL1RL2/TNF/TICAM1/STAT1/CARD11/CD55/NOS2/MAPK11/RFTN1/BATF/CD274/LGALS9/SAA1/LY96/TLR2/EIF2AK3/DDIT3/IL18R1/IFNGR1/TLR4/ATF4/PTAFR/TRIM16/CLEC7A/HLA-G/PRKCQ/HLA-F/PTPRJ/FERMT1/EIF2AK2/IRAK3/CD276/IL36A/CYP1B1/CD46/AKAP12/CADM1/CD200/MMP12/BTN3A1/PANX1/NOD2/SPHK1/IFI16/C1QTNF3/PELI1/AKIRIN2/BCL10/DHX58/CD40/HLA-E/ISL1/IRAK1/PTPN22/ANXA1/F2RL1/SERPINF2/NFATC4/PNP/SYK/PANX2/ADAM17/POLR3D/FURIN/CEBPG/POLR3B/HMOX1/SPON2/BCL3/RIPK2/TRAF2/NLRP1/SRC/MALT1/SLC7A5/NOD1/IL4R/TYK2/TMEM106A/EGR1/F3/CD86/IL15/LACC1/HYAL2/IL1R1/CEBPB/IRF1
GOBP_SPINDLE_ASSEMBLY 119 -0.5800238 -2.147857 0.0000000 0.0000034 0.0000028 1273 MAP10/RACGAP1/FBXO5/KIF11/AURKA/KIF23/GOLGA8M/KIF15/SPAG5/NDC80/PLK1/NEK2/CCNB2/KIF4A/TPX2/GOLGA8H/CDC20/KIFC1/ASPM/MYBL2
GOBP_MONONUCLEAR_CELL_MIGRATION 129 0.5908789 2.092512 0.0000000 0.0000038 0.0000030 2149 S100A7/CXCL10/CXCL11/CCL22/CCL4/CCL20/S100A12/SLIT2/CCL5/CCN3/THBS1/PECAM1/SERPINE1/ADAM8/CXCL17/CX3CL1/ASB2/TNF/CXCL16/RIPK3/CD47/ARTN/LGALS9/SAA1/STK10/PDGFB/SPNS2/PTPRO/ICAM1/GREM1/OXSR1/RARRES2/MSN/ADTRP/IL34/CSF1/LYN/CD200/FLT1/TNFSF14/LGMN/CCL17/SLC8B1/DUSP1/ITGB7/MAPK3/ANXA1/MOSPD2/TRPM4/ADAM17/XG
GOBP_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN 247 0.5033246 1.923663 0.0000000 0.0000038 0.0000031 2975 S100A7/CXCL10/CXCL11/IL36G/CXCL9/IDO1/CMPK2/CXCL2/TNIP3/CXCL6/NR4A1/CXCL3/CXCL8/SNCA/ALPL/CCL5/LBP/FOXP3/CXCL5/IL1B/KMO/VCAM1/CXCL1/ZC3H12A/PTGS2/CNR1/SCARB1/IRAK2/CSF3/EDN1/PF4V1/FOS/SERPINE1/ARID5A/MYD88/ANKRD1/IL1A/CX3CL1/TNIP1/S100A8/TNF/BMP6/TNFRSF1B/TICAM1/CD55/NFKBIA/NOS2/PCK2/CD274/LGALS9/LY96/TNFAIP3/TLR2/MEF2C/TRIM5/TLR4/PTAFR/TNIP2/ASS1/JUND/GCH1/S100A9/DUSP10/ADAM9/IRAK3/SELENOS/IL36A/LYN/AKAP12/TRIB1/LDOC1/GFI1/SELP/PALM3/NOD2/PELI1/AKIRIN2/NOCT/BCL10/IRAK1/PTPN22/VIM/SBNO2/MAPK3/ADAM17/SMAD6/SPON2/RIPK2/CAPN2/SRC/MALT1/PLAA/ZFP36/CLDN1/CD86/AKAP8/S100A14/CEBPB/MAP2K3/NFKB1/NFKBIB/C2/IL18/DAB2IP/MAPKAPK2/CNP/GJB6/CASP8
GOBP_MONONUCLEAR_CELL_DIFFERENTIATION 310 0.4686337 1.833318 0.0000000 0.0000039 0.0000031 2810 NTRK1/MT1G/FGL2/FZD9/RSAD2/DLL4/FASN/TNFSF9/BATF3/CLCF1/BATF2/FOXP3/KLF6/IL1B/VCAM1/HDAC9/IRF7/ZC3H12A/IL23A/IKZF1/IL31RA/RELB/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/VEGFA/LAG3/RIPK3/CARD11/LGALS1/GPR68/VNN1/FANCA/JUN/BATF/UBD/LGALS9/PRDM1/IL18R1/DOCK10/HLA-G/LRRC8A/PTPRJ/IL11/ITGB8/INHBA/DUSP10/DNAJB9/MYC/IL34/CSF1/CD46/TYRO3/LYN/NFKBIZ/IL15RA/NFKBID/IFI16/SOX4/CTNNBIP1/TMEM176A/IL7R/PTPN22/TOX/SRF/ZEB1/ANXA1/PTPN2/F2RL1/PRELID1/PNP/SYK/ADAM17/ITGB6/CEBPG/MMP14/TMEM176B/HLA-B/BCL3/RIPK2/MALT1/GPS2/ST3GAL1/IL4R/EGR1/NFIL3/BAK1/CMTM7/CD86/IL15/ZBTB46/CEBPB/IRF1/WNT4/SOS2/IL18/MYH9
GOBP_RESPONSE_TO_INTERLEUKIN_1 102 0.6276355 2.149179 0.0000000 0.0000040 0.0000032 2718 ZBP1/HYAL1/CCL22/CCL4/CCL20/CXCL8/HYAL3/SNCA/IL1R2/CCL5/KLF2/IL1B/KMO/ZC3H12A/IRAK2/EDN1/MYD88/GBP2/ANKRD1/IL1RN/CX3CL1/IL1RL2/MAPK11/SOX9/GBP1/CD47/LGALS9/MTHFR/TNIP2/IRAK3/MYC/AKAP12/ST18/CCL17/CD40/IRAK1/MAPK3/ANXA1/RIPK2/SRC/EGR1/GBP3/HYAL2/IL1R1/CEBPB/NFKB1/RPS6KA4
GOBP_CHROMOSOME_LOCALIZATION 79 -0.6293357 -2.212280 0.0000001 0.0000045 0.0000037 758 MAD1L1/CCNB1/MAJIN/CDCA8/KIF18A/PSRC1/CDT1/CENPF/KIF14/FAM83D/SPAG5/NDC80/CENPE/CDCA5/DLGAP5/NUF2/KIF2C/KIFC1/CEP55
GOBP_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 81 0.6580286 2.177212 0.0000001 0.0000051 0.0000041 2718 ZBP1/HYAL1/CCL22/CCL4/CCL20/CXCL8/HYAL3/IL1R2/CCL5/KLF2/IL1B/KMO/ZC3H12A/IRAK2/EDN1/MYD88/GBP2/ANKRD1/IL1RN/CX3CL1/IL1RL2/MAPK11/SOX9/GBP1/CD47/TNIP2/IRAK3/MYC/AKAP12/ST18/CCL17/CD40/IRAK1/MAPK3/EGR1/GBP3/HYAL2/IL1R1/CEBPB/NFKB1/RPS6KA4
GOBP_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS 287 0.4756739 1.840973 0.0000001 0.0000051 0.0000041 2470 TNFAIP6/FGL2/ISG15/LDLR/IDO1/SLIT2/OAS3/MICA/OAS1/FOXP3/IL1RL1/BST2/NLRC5/CCN3/THBS1/TSC22D3/ZC3H12A/CNR1/CEACAM1/LRRC17/C5AR2/FYN/USP18/IL31RA/IL4I1/CX3CL1/SOCS1/TNF/LAG3/CD55/GPR68/SOX9/GBP1/CD47/CD274/LGALS9/FSTL3/C4BPA/UBASH3A/SERPINB4/TNFAIP3/SERPINB9/NMI/TRIM21/TGFB2/TLR4/PARP14/HLA-G/KLRD1/HLA-F/PTPRJ/GREM1/INHBA/DUSP10/RHBDF2/ADTRP/IRAK3/DUSP3/SELENOS/MYC/CD46/TYRO3/LYN/TRIB1/CD200/MMP12/ARG2/HLA-DOB/STAT2/NOD2/IFI16/PELI1/TMEM176A/DHX58/IL7R/FCRLB/HLA-E/PTPN22/TRAFD1/DUSP1/ADAR/ANXA1/PTPN2/PDE5A/THY1/SYK/FURIN/TMEM176B/HLA-B/HMOX1/SRC/GPS2/IL4R/LPXN/AHR
GOBP_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS 470 0.4214983 1.704118 0.0000001 0.0000052 0.0000042 1209 PLA2G3/PNPLA3/APOC1/ACAT2/FADS2/ELOVL6/ACSS2/MSMO1/FADS1/INSIG1/ALDOB/FGFR4/ACOT1/LIPC/ACLY/LIPG/LPIN1/SLC2A6/SCD/MLXIPL/STARD4/IDO1/FASN/TRIB3/ALDOC/HKDC1/ALOXE3/ACSL1/PLA2G4C/NPC1/SNCA/TBXAS1/NUDT8/HSD17B12/ME1/KYNU/ACSL4/IL1B/KMO/ACOXL/PTGS2/CNR1/CEACAM1/CYP46A1/ELOVL5/GGT5/NR4A3/EDN1/AACS/ALDH1L2/IL4I1/MFSD2A/CYP3A5/CYP26B1/ELOVL7/FA2H/ACADL/VNN1/SOX9/ACACA/PCK2/IDH1/ECH1/CYP4A22/LIPH/PGD/PEDS1/ALDH1A3/PTGES/MTHFD1L/UGT1A10/ADIPOR2
GOBP_MEIOTIC_CELL_CYCLE 198 -0.4943421 -1.985473 0.0000001 0.0000056 0.0000045 2172 PLD6/M1AP/PSMC3IP/MYBL1/SMC4/CENPC/FANCM/ERCC1/RSPH1/CKS2/HSF2BP/RNF212/TDRD9/SMC2/FMN2/MAPK15/PKMYT1/EME1/MNS1/SYCP2/FBXO5/WBP2NL/MCMDC2/BRIP1/CCNE1/AURKA/TRIP13/MAJIN/CDC25C/RAD51/CDC25A/KIF18A/XRCC2/PTTG1/SGO2/RAD51AP1/ESPL1/CCNE2/FBXO43/TTK/NDC80/RAD54B/PLK1/NEK2/CNTD1/EXO1/RAD54L/CCNB2/BUB1/NUF2/DMC1/CDC20/NCAPH/SGO1/BUB1B/TOP2A/ASPM
GOBP_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION 51 0.7326857 2.225637 0.0000001 0.0000058 0.0000047 1780 APOBEC3A/ISG15/RSAD2/IFITM1/IFIT1/OAS3/OASL/ISG20/OAS1/MX1/CCL5/OAS2/BST2/IFIH1/APOBEC3B/IFITM3/TNIP1/TNF/IFIT5/PLSCR1/EIF2AK2/SHFL/IFI16/N4BP1
GOBP_CELLULAR_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN 154 0.5553555 2.007864 0.0000001 0.0000058 0.0000047 2733 CXCL10/CXCL11/IL36G/CXCL9/CMPK2/CXCL2/TNIP3/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/KMO/CXCL1/ZC3H12A/SCARB1/IRAK2/CSF3/PF4V1/SERPINE1/ARID5A/MYD88/ANKRD1/IL1A/CX3CL1/TNIP1/TNF/BMP6/TNFRSF1B/TICAM1/CD55/NFKBIA/NOS2/CD274/LY96/TNFAIP3/TLR2/MEF2C/TRIM5/TLR4/PTAFR/TNIP2/ASS1/ADAM9/SELENOS/IL36A/LYN/TRIB1/LDOC1/GFI1/NOD2/BCL10/IRAK1/PTPN22/VIM/SBNO2/MAPK3/SPON2/RIPK2/CAPN2/SRC/MALT1/PLAA/ZFP36/CD86/AKAP8/CEBPB/MAP2K3/NFKB1/NFKBIB
GOBP_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE 61 -0.6788663 -2.280874 0.0000001 0.0000062 0.0000050 1732 HECW2/XRCC3/MAPK15/FBXO5/ANAPC4/MAD1L1/TRIP13/CCNB1/ZWINT/CDT1/CENPF/ESPL1/TACC3/TTK/MAD2L1/NDC80/PLK1/CENPE/BUB1/DLGAP5/BUB1B/UBE2C
GOBP_CHROMOSOME_SEPARATION 88 -0.6253701 -2.247633 0.0000001 0.0000068 0.0000055 861 HECW2/XRCC3/MAPK15/EME1/FBXO5/ANAPC4/MAD1L1/TRIP13/CCNB1/ZWINT/PTTG1/CDT1/CENPF/ESPL1/TACC3/TTK/MAD2L1/NDC80/PLK1/CENPE/BUB1/DLGAP5/NCAPH/BUB1B/UBE2C/TOP2A
GOBP_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 381 -0.4017565 -1.702334 0.0000001 0.0000070 0.0000056 1732 HECW2/CIT/XRCC3/JADE1/BRCA1/CENPJ/MTBP/MRNIP/PKMYT1/CAMK2A/CDC7/CDC14A/GPNMB/STOX1/FBXO5/LZTS1/GJC2/EZH2/KDM8/ANAPC4/CCNF/ORC1/CCNE1/AURKA/MAD1L1/E2F1/CCNP/TRIP13/CCNB1/ATAD5/BLM/CCNO/CDC25C/CCNA2/CDC25A/CDKN2C/ZWINT/CDT1/CENPF/CDKN3/CLSPN/ESPL1/E2F7/KIF14/CCNE2/TACC3/MELK/TTK/MAD2L1/TICRR/FBXL22/ANLN/CDK1/NDC80/FOXM1/PLK1/CENPE/CCNB2/CDCA5/BUB1/DLGAP5/IQGAP3/RRM2/DTL/GTSE1/BUB1B/UBE2C
GOBP_REGULATION_OF_CHROMOSOME_ORGANIZATION 201 -0.4889944 -1.961285 0.0000001 0.0000082 0.0000066 861 H3-3A/SLF1/SMC4/TENT4B/ERCC1/SMC2/HECW2/XRCC3/MAPK15/ATF7IP2/RMI2/AXIN2/FBXO5/ANAPC4/MAD1L1/TRIP13/CCNB1/ZWINT/PTTG1/CDT1/CENPF/ESPL1/TACC3/TTK/MAD2L1/NDC80/PLK1/CENPE/NEK2/CDCA5/BUB1/DLGAP5/NCAPH/BUB1B/UBE2C/TOP2A/NCAPG
GOBP_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS 476 0.4200914 1.700797 0.0000001 0.0000089 0.0000072 1983 PNPLA3/MVD/HMGCS1/ELOVL6/ACSS2/FDPS/FADS1/IDI1/QPRT/ACLY/LPIN1/IDO1/CMPK2/MVK/ENTPD8/ACSL1/PLA2G4C/FGF2/IDO2/SNCA/HSD17B12/SLC25A1/ME1/KYNU/SLC5A8/ACSL4/PANK3/LCAT/PANK1/KMO/SRD5A3/ELOVL5/SOCS2/NAMPT/ABHD4/ADCY10/MFSD2A/PCYT2/ELOVL7/SOCS1/SELENOI/PARP9/G6PD/NOS2/ACACA/IDH1/SOCS3/LIPH/TPK1/PI4K2A/PDGFB/PISD/PTAFR/CDA/GARS1/PLSCR1/GCH1/GPAT3/PIGW/CHP1/ELOVL1/MYC/ADCY4/HAAO/ADCY5/PDXK/ITPKC/UCKL1/ANTKMT/SERINC4/LPCAT1/PIK3C2G/PPARGC1A/CTPS1/GPAT4/NADK/UPP1/ACOT7/HRH1/HACD2
GOBP_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS 158 0.5390324 1.952537 0.0000001 0.0000097 0.0000078 1147 PLA2G3/APOC1/FADS2/ELOVL6/FADS1/INSIG1/FGFR4/LIPC/ACLY/LIPG/SCD/MLXIPL/STARD4/IDO1/FASN/TRIB3/ALOXE3/TBXAS1/HSD17B12/IL1B/KMO/PTGS2/CEACAM1/CYP46A1/ELOVL5/EDN1/ELOVL7/FA2H/ACADL/ACACA/LIPH/ALDH1A3/PTGES
GOBP_CELL_CYCLE_PHASE_TRANSITION 467 -0.3847485 -1.667139 0.0000002 0.0000100 0.0000081 1732 HECW2/CIT/XRCC3/JADE1/MAPK15/BRCA1/CENPJ/MTBP/MRNIP/PKMYT1/CAMK2A/CDC7/CDC14A/EME1/NEK10/GPNMB/SIX3/STOX1/FBXO5/STK33/LZTS1/GJC2/EZH2/KDM8/BRIP1/ANAPC4/CCNF/ORC1/CCNE1/AURKA/MAD1L1/E2F1/CCNP/TRIP13/CCNB1/ATAD5/NANOGP8/BLM/CCNO/CDC25C/CCNA2/DNA2/CDC25A/CDKN2C/ZWINT/CDT1/CENPF/CDKN3/CLSPN/ESPL1/E2F7/KIF14/FAM83D/CCNE2/TACC3/MELK/TTK/MAD2L1/TICRR/FBXL22/ANLN/CDK1/NDC80/FOXM1/PLK1/CENPE/CCNB2/CDCA5/BUB1/DLGAP5/IQGAP3/RRM2/CDC45/DTL/GTSE1/BUB1B/UBE2C
GOBP_REGULATION_OF_CELL_ACTIVATION 434 0.4201055 1.686319 0.0000002 0.0000101 0.0000082 3181 PLA2G3/FGL2/EBI3/CD70/THEMIS2/LDLR/IDO1/TNFSF9/MICA/ITGAM/SNCA/CCL5/CLCF1/LBP/IGF2/FOXP3/IL1RL1/IL1B/VCAM1/THBS1/ZC3H12A/IL23A/CNR1/CEACAM1/CD177/NR4A3/FYN/IL31RA/CAMK4/IL4I1/ADAM8/CYP26B1/MYD88/CD83/TNFSF13B/EMILIN2/IL1A/CX3CL1/SOCS1/IL1RL2/TNFRSF13C/TNF/TNFRSF1B/LAG3/RIPK3/TICAM1/CARD11/LGALS1/CD55/VNN1/FANCA/STXBP1/ADGRE2/UNC13D/CD47/CD274/LGALS9/PRDM1/C1QTNF1/TNFAIP3/PLPP6/PDGFB/MEF2C/TLR4/PTAFR/TNIP2/CLEC7A/SH2B3/HLA-G/JUND/PLSCR1/PRKCQ/HLA-F/CDKN1A/INHBA/DUSP10/DUSP3/CD276/STX4/CD46/TYRO3/LYN/NFKBIZ/PRKG1/CD200/IRS2/ARG2/IL15RA/BLOC1S3/HLA-DOB/TNFSF14/NFKBID/SELP/GAB2/MAPK8IP1/NOD2/SPHK1/PELI1/SOX4/BCL10/CD40/IL7R/HLA-E/MAP3K8/PTPN22/TOX/ZEB1/ANXA1/PTPN2/F2RL1/SHLD1/PRELID1/PDE5A/THY1/PNP/SYK/CD9/SHLD2/MMP14/HMOX1/RIPK2/SERPINE2/SLC7A1/SRC/MALT1/IL4R/TYK2/AHR/TFRC/CD86/IL15/NECTIN2/NCK1/CTSC/CEBPB/IRF1/SOS2/MFHAS1/IL18/RHBDD3/SHLD3/FADD/SLC15A4/ZBTB7B/PLA2G4A/TIRAP/HLA-A/BTN2A2/PTPN11/TGFBR2/SIRPA/HLA-DMA/PDPN/SH3KBP1/ACTA2/CAV1
GOBP_REGULATION_OF_CHROMOSOME_SEPARATION 66 -0.6676471 -2.264416 0.0000002 0.0000110 0.0000088 1115 HECW2/XRCC3/MAPK15/FBXO5/ANAPC4/MAD1L1/TRIP13/CCNB1/ZWINT/PTTG1/CDT1/CENPF/ESPL1/TACC3/TTK/MAD2L1/NDC80/PLK1/CENPE/BUB1/DLGAP5/BUB1B/UBE2C
GOBP_MEIOSIS_I_CELL_CYCLE_PROCESS 98 -0.5856143 -2.119285 0.0000002 0.0000110 0.0000088 2118 M1AP/PSMC3IP/MYBL1/CENPC/FANCM/ERCC1/CKS2/HSF2BP/RNF212/TDRD9/FMN2/MAPK15/EME1/SYCP2/FBXO5/BRIP1/CCNE1/AURKA/TRIP13/MAJIN/CDC25C/RAD51/CDC25A/PTTG1/SGO2/RAD51AP1/ESPL1/CCNE2/NDC80/RAD54B/PLK1/CNTD1/RAD54L/CCNB2/DMC1/SGO1/TOP2A
GOBP_MICROTUBULE_BASED_MOVEMENT 330 -0.4226722 -1.765346 0.0000002 0.0000110 0.0000088 3064 TRAF3IP1/SPAG6/KIF17/SYBU/IFT74/CFAP100/DYNC2I1/ZMYND10/ODAD4/SSX2IP/CFAP91/ARMC2/TTC29/CFAP251/DNAAF11/TTLL9/KIF27/CFAP47/DYNLT5/DYNLT2B/IFT43/AQP4/CFAP46/HOATZ/SPA17/TTLL3/BBS2/CFAP69/DNAAF4/KIF24/DYNC2LI1/CFAP58/ENO4/IFT52/TMEM201/ODAD1/AGBL4/IFT122/IFT140/CCDC40/GAS2L2/CFAP52/IFT57/KIF6/CFAP54/RSPH9/DYNLT2/ZBBX/DRC7/IFT27/ODAD3/WDR35/SPAG17/DZIP1/MAPK8IP3/CFAP73/CFAP157/NME5/PCM1/IFT88/LCA5/DAW1/TTC12/DNAI1/IFT81/DNAH7/IQCG/RPGR/SPEF2/CCDC39/DPCD/FMN2/MAP1A/SPAG16/IFT172/SLC22A16/CFAP61/KIF19/TEKT3/ROPN1L/KIF1A/ROPN1B/CCDC65/HYDIN/STARD9/CFAP206/KIF22/TEKT2/TEKT1/RFX3/DNAH9/TTC21A/TCTE1/DNAI4/CFAP45/CFAP65/DYNC2H1/NEK10/TTC21B/DNAI2/DNAH3/CFAP44/TEKT4/MNS1/TEKT5/KIF21A/DNAH6/DNAH1/DNAH5/CFAP70/CFAP43/DYNLRB2/CFAP221/ODAD2/LCA5L/DNAH10/DNAAF6/DLG2/DNAAF1/CFAP53/KIF11/TTLL6/CNIH2/DNAH2/PLTP/DNAH12/CATSPERD/MEIG1/KIF18A/KIF23/KIF14/KIF20B/KIF15/DYNLT4/EPPIN/CENPE/KIF20A/KIF4A/DLGAP5/KIF2C/KIFC1/KIF18B
GOBP_METAPHASE_PLATE_CONGRESSION 64 -0.6691102 -2.254788 0.0000002 0.0000128 0.0000103 758 MAD1L1/CCNB1/CDCA8/KIF18A/PSRC1/CDT1/CENPF/KIF14/FAM83D/SPAG5/NDC80/CENPE/CDCA5/NUF2/KIF2C/KIFC1/CEP55
GOBP_NEUTROPHIL_MIGRATION 88 0.6269365 2.101853 0.0000002 0.0000134 0.0000108 780 TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/ITGA9/CXCL1/IL23A/C5AR2/CD177/OLFM4/EDN1/PECAM1/PF4V1/ADAM8/MYD88/IL1A/CX3CL1/S100A8
GOBP_RESPONSE_TO_TYPE_I_INTERFERON 58 0.6928133 2.163279 0.0000002 0.0000146 0.0000118 2005 ZBP1/ISG15/IFITM1/IFIT1/OAS3/OAS1/MX1/OAS2/IFI27/NLRC5/IRF7/USP18/IFITM3/MYD88/STAT1/IKBKE/MMP12/STAT2/SP100/SHFL/IRAK1/USP27X/ADAR/PTPN2
GOBP_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS 180 0.5281664 1.956603 0.0000003 0.0000148 0.0000119 2733 CXCL10/CXCL11/IL36G/CXCL9/CMPK2/CXCL2/TNIP3/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/KMO/CXCL1/ZC3H12A/SCARB1/IRAK2/CSF3/PF4V1/SERPINE1/ARID5A/MYD88/ANKRD1/IL1A/CX3CL1/TNIP1/TNF/BMP6/TNFRSF1B/TICAM1/CD55/NFKBIA/NOS2/CD274/LY96/TNFAIP3/TLR2/EIF2AK3/DDIT3/MEF2C/TRIM5/TLR4/PTAFR/TNIP2/ASS1/CDA/CLEC7A/ADAM9/SELENOS/IL36A/LYN/TRIB1/LDOC1/GFI1/NOD2/BCL10/IRAK1/PTPN22/VIM/SBNO2/MAPK3/SYK/SPON2/RIPK2/CAPN2/SRC/MUS81/MALT1/PLAA/ZFP36/CD86/AKAP8/TIGAR/CEBPB/MAP2K3/NFKB1/NFKBIB
GOBP_REGULATION_OF_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 269 -0.4339404 -1.775033 0.0000003 0.0000163 0.0000132 1732 HECW2/XRCC3/JADE1/BRCA1/CENPJ/MTBP/MRNIP/CDC7/CDC14A/GPNMB/STOX1/FBXO5/GJC2/EZH2/ANAPC4/ORC1/AURKA/MAD1L1/E2F1/TRIP13/CCNB1/ATAD5/BLM/CDC25C/CDC25A/CDKN2C/ZWINT/CDT1/CENPF/CLSPN/ESPL1/E2F7/KIF14/TTK/MAD2L1/TICRR/ANLN/CDK1/NDC80/PLK1/CENPE/CDCA5/BUB1/DLGAP5/RRM2/DTL/GTSE1/BUB1B/UBE2C
GOBP_VIRAL_PROCESS 357 0.4371036 1.733938 0.0000003 0.0000163 0.0000132 3596 APOBEC3A/CCL4/ISG15/RSAD2/LDLR/IFITM1/IFIT1/OAS3/OASL/ISG20/CXCL8/OAS1/MX1/NPC1/CCL5/OAS2/IFI27/BST2/IRF7/IFIH1/ZC3H12A/SCARB1/APOBEC3B/IFITM3/LAMP3/CLDN9/PARP9/TNIP1/TNF/TRIM31/STAT1/LGALS1/CD55/IFIT5/JUN/LGALS9/TRIM21/TRIM5/ICAM1/PLSCR1/TRIM14/PVR/EIF2AK2/SLC3A2/NECTIN4/MGAT4C/CD46/TYRO3/TPCN2/CHMP7/ITGB3/TMEM41B/ACE2/GFI1/SLC52A2/SHFL/PIK3C2G/IFI16/N4BP1/CHMP6/ADAR/ITGB7/BICD1/TRIM25/ITGAV/FURIN/ITGB6/MGAT4A/IFITM2/TRIM22/STOM/VPS37B/ST3GAL1/PARP10/KPNA2/TFRC/SRPK1/ZFP36/LY6E/CLDN1/CD86/MON1B/EPHA2/NECTIN2/HYAL2/PPIA/DAG1/CAV2/ZNFX1/MGAT4B/POU2F3/P4HB/NEDD4/RNASEK/RRP1B/SMPD1/VPS18/ITGA5/ITGB5/MGAT5/HEXIM1/VCP/CAV1/CFL1/CHMP1B/TRIM27/EDEM2/PARP16/ST3GAL4/SLC1A5/CHMP4C/SLC52A1/SP1/MORC2/RAB43/PKN2/ZC3HAV1/APOBEC3F/APOBEC3G/VPS37D/SCARB2
GOBP_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS 101 0.6038062 2.061317 0.0000003 0.0000174 0.0000141 2172 MVD/HMGCS1/ELOVL6/ACSS2/HMGCR/ACOT1/ACLY/MVK/ACSL1/SNCA/NUDT8/HSD17B12/SLC25A1/ACSL4/PANK3/PANK1/ELOVL5/ELOVL7/ACACA/ENPP1/ELOVL1/ACOT2/ACOT9/OGDH/GPAT4/ACOT7/HACD2/ACSL5/FAR2/ELOVL4
GOBP_REGULATION_OF_MITOTIC_CELL_CYCLE 408 -0.3938066 -1.670572 0.0000003 0.0000178 0.0000144 1732 HECW2/XRCC3/JADE1/BRCA1/CENPJ/MTBP/MRNIP/PKMYT1/GMNN/CDC7/CDC14A/EME1/GPNMB/STOX1/FBXO5/STK33/BTG4/GJC2/BMP7/MCIDAS/EZH2/ANAPC4/TTC28/ORC1/AURKA/MAD1L1/E2F1/TRIP13/CCNB1/ATAD5/BLM/GAS1/CDC25C/CDC25A/CDKN2C/ZWINT/CDT1/CENPF/CLSPN/ESPL1/E2F7/KIF14/KIF20B/FBXO43/TTK/MAD2L1/TICRR/ANLN/CDK1/SMOC2/NDC80/PLK1/CENPE/NEK2/CDCA5/BUB1/DLGAP5/CDCA2/IGF1/RRM2/DTL/GTSE1/BUB1B/UBE2C/MKI67
GOBP_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION 352 -0.4074752 -1.711448 0.0000006 0.0000326 0.0000263 1732 HECW2/XRCC3/JADE1/MAPK15/BRCA1/CENPJ/MTBP/MRNIP/CDC7/CDC14A/EME1/NEK10/GPNMB/SIX3/STOX1/FBXO5/STK33/GJC2/EZH2/BRIP1/ANAPC4/ORC1/AURKA/MAD1L1/E2F1/TRIP13/CCNB1/ATAD5/NANOGP8/BLM/CDC25C/DNA2/CDC25A/CDKN2C/ZWINT/CDT1/CENPF/CLSPN/ESPL1/E2F7/KIF14/FAM83D/TTK/MAD2L1/TICRR/ANLN/CDK1/NDC80/PLK1/CENPE/CDCA5/BUB1/DLGAP5/RRM2/CDC45/DTL/GTSE1/BUB1B/UBE2C
GOBP_REGULATION_OF_LEUKOCYTE_MIGRATION 155 0.5377855 1.946737 0.0000006 0.0000346 0.0000279 2286 S100A7/TNFAIP6/CXCL10/CCL4/CCL20/SLIT2/CXCL8/CCL5/LBP/CCN3/THBS1/IL23A/C5AR2/OLFM4/EDN1/SERPINE1/ADAM8/MYD88/CXCL17/IL1A/CX3CL1/TNF/VEGFA/RIPK3/CD47/LGALS9/STK10/PTAFR/ICAM1/GREM1/OXSR1/RARRES2/MSN/ADTRP/IL34/CSF1/LYN/CD200/TNFSF14/SELP/LGMN/SLC8B1/NOD2/RHOG/DUSP1/MAPK3/ANXA1/F2RL1/MOSPD2/THY1/ADAM17/CD9/XG/MMP14/P2RX4/HMOX1/DAPK2
GOBP_DNA_REPLICATION_DEPENDENT_CHROMATIN_ORGANIZATION 29 -0.7840550 -2.241883 0.0000007 0.0000362 0.0000292 1304 H3C11/H4C12/H4C4/CHAF1B/H3C1/H3C10/H4C13/H4C1/H3C7/H4C9/ASF1B/H3C12/H3C3/H3C8/H3C2
GOBP_IMMUNE_EFFECTOR_PROCESS 393 0.4353188 1.735132 0.0000007 0.0000362 0.0000292 2694 PLA2G3/FGL2/CD70/RSAD2/TCIM/CXCL6/MICA/NCF1/ITGAM/LAT2/CLCF1/LBP/FOXP3/IL1B/BST2/IRF7/ZC3H12A/IL23A/CEACAM1/SH2D1B/CD177/NR4A3/FYN/PLPP4/IFI35/RELB/CAMK4/IL4I1/ARID5A/MYD88/SEMA7A/ANXA3/KLK7/TNF/TNFRSF1B/COLEC10/LAG3/RIPK3/TICAM1/DYSF/LGALS1/CD55/NOS2/STXBP1/ADGRE2/RFTN1/BATF/UNC13D/CD47/CFB/LGALS9/C4BPA/SERPINB4/DDX60/SERPINB9/NMI/RAET1E/TGFB2/IL18R1/TLR4/PTAFR/ICAM1/DOCK10/CLEC7A/ULBP1/HLA-G/KLRD1/C1S/HLA-F/PVR/PTPRJ/DUSP10/DNAJB9/LCP1/IRAK3/STX4/CD46/LYN/ULBP3/NFKBIZ/CADM1/HLA-DOB/NFKBID/GAB2/NOD2/BCL10/DHX58/CD40/IL7R/HLA-E/PTPN22/SBNO2/ULBP2/ANXA1/F2RL1/SHLD1/TRPM4/SYK/C8B/ADAM17/SHLD2/CEBPG/RNF168/HLA-B/HMOX1/SPON2/BCL3/RIPK2/TREM1/TRAF2/SRC/MALT1/SLC7A5/ST3GAL1/IL4R/RAB27A/AHR/TUBB/TFRC/CD86/LACC1/NECTIN2/CTSC/IL1R1/SWAP70
GOBP_TELOMERE_ORGANIZATION 151 -0.5026711 -1.938191 0.0000008 0.0000422 0.0000340 3362 H4C3/NAF1/POT1/PTGES3/FEN1/ATM/ATR/H4C2/MRE11/H3C6/WRN/ZBTB48/TCP1/SMC6/HDAC8/H4C6/H3-3A/WRAP53/H3C11/HSP90AA1/TENT4B/H4C12/ERCC1/H4C4/XRCC3/MAPK15/H3C1/H3C10/EZH2/CCNE1/H4C13/BLM/DNA2/RAD51/RECQL4/H4C1/CCNE2/H3C7/ZSCAN4/H4C9/NEK2/EXO1/H3C12/H3C3/H3C8/H3C2
GOBP_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION 99 -0.5651321 -2.057771 0.0000009 0.0000468 0.0000377 1115 FBXO5/BMP7/ANAPC4/AURKA/MAD1L1/TRIP13/CCNB1/CDC25C/ZWINT/CDT1/CENPF/ESPL1/KIF20B/FBXO43/TTK/MAD2L1/NDC80/PLK1/NEK2/BUB1/DLGAP5/CDCA2/IGF1/BUB1B/MKI67
GOBP_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION 82 0.6307461 2.092302 0.0000009 0.0000473 0.0000382 2105 S100A7/CXCL10/CCL4/CCL20/SLIT2/CCL5/CCN3/THBS1/SERPINE1/ADAM8/CXCL17/TNF/RIPK3/CD47/LGALS9/STK10/GREM1/OXSR1/RARRES2/MSN/ADTRP/IL34/CSF1/LYN/CD200/TNFSF14/LGMN/SLC8B1/DUSP1/MAPK3/MOSPD2/ADAM17
GOBP_DNA_REPLICATION 266 -0.4311322 -1.759924 0.0000009 0.0000481 0.0000388 3134 TOP1MT/ATR/MCM4/NAP1L1/ING4/MRE11/POLH/WRN/ALYREF/RMI1/GINS4/NASP/LIG3/POLI/PRIMPOL/MMS22L/DBF4B/CCDC88A/RUVBL2/NFIX/RRM1/ENDOG/FANCM/RFC3/ZGRF1/ZRANB3/JADE1/GMNN/POLN/CDC7/EME1/RMI2/GMNC/LRWD1/CHAF1B/ORC6/WDHD1/FBXO5/DSCC1/GLI2/POLD1/MCIDAS/PCLAF/GINS1/ORC1/CCNE1/ATAD5/BLM/CCNA2/DNA2/RAD51/RECQL4/GINS2/CDT1/E2F7/CCNE2/POLQ/TICRR/CDK1/ADRA2A/ESCO2/POLE2/MCM10/RRM2/CDC45/DTL/FAM111B
GOBP_NEUTROPHIL_CHEMOTAXIS 72 0.6501920 2.111644 0.0000010 0.0000498 0.0000402 1135 TNFAIP6/CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/S100A12/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/LBP/CXCL5/IL1B/ITGA9/CXCL1/IL23A/C5AR2/EDN1/PF4V1/CX3CL1/S100A8/SAA1/TGFB2
GOBP_ORGANIC_ACID_BIOSYNTHETIC_PROCESS 237 0.4827036 1.842572 0.0000010 0.0000504 0.0000407 1348 PLA2G3/APOC1/FADS2/ELOVL6/FADS1/INSIG1/FGFR4/LIPC/ACLY/LIPG/SCD/MLXIPL/STARD4/IDO1/FASN/TRIB3/ALOXE3/TBXAS1/HSD17B12/GGT7/KYNU/IL1B/KMO/PSAT1/PTGS2/CEACAM1/CYP46A1/ELOVL5/GGT5/EDN1/ELOVL7/FA2H/ACADL/ACACA/PYCR1/CYP4A22/LIPH/MTHFR/ALDH1A3/PTGES/MTHFD1L/ASS1/PLOD3/CBS/ELOVL1
GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY 164 0.5240875 1.917341 0.0000010 0.0000512 0.0000413 2945 PLA2G3/RSAD2/CXCL6/MICA/ITGAM/CLCF1/FOXP3/IL1B/BST2/IL23A/CEACAM1/SH2D1B/CD177/CAMK4/IL4I1/ARID5A/TNF/TNFRSF1B/LAG3/RIPK3/TICAM1/CD55/NOS2/STXBP1/ADGRE2/UNC13D/LGALS9/C4BPA/SERPINB4/SERPINB9/RAET1E/IL18R1/TLR4/PTAFR/ICAM1/CLEC7A/HLA-G/KLRD1/HLA-F/PVR/STX4/CD46/LYN/CADM1/GAB2/NOD2/CD40/IL7R/HLA-E/F2RL1/SHLD1/TRPM4/SYK/SHLD2/HLA-B/HMOX1/TRAF2/MALT1/IL4R/AHR/TFRC/NECTIN2/IL1R1/IL18/C3/SHLD3/FADD/SLC15A4
GOBP_SISTER_CHROMATID_COHESION 54 -0.6790918 -2.214973 0.0000011 0.0000528 0.0000426 1521 KIF22/AXIN2/DSCC1/HASPIN/SGO2/ESPL1/PLK1/ESCO2/CDCA5/BUB1/CDC20/SGO1/BUB1B
GOBP_RESPONSE_TO_CHEMOKINE 53 0.6919856 2.134764 0.0000011 0.0000550 0.0000443 720 CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/CCR3/SLIT2/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/CXCL5/CXCL1/ZC3H12A/EDN1/PF4V1/CX3CL1
GOBP_VIRAL_LIFE_CYCLE 267 0.4598451 1.770410 0.0000012 0.0000556 0.0000449 3596 APOBEC3A/ISG15/RSAD2/LDLR/IFITM1/IFIT1/OAS3/OASL/ISG20/CXCL8/OAS1/MX1/NPC1/CCL5/OAS2/IFI27/BST2/IFIH1/ZC3H12A/SCARB1/APOBEC3B/IFITM3/LAMP3/CLDN9/TNIP1/TNF/TRIM31/LGALS1/CD55/IFIT5/LGALS9/TRIM21/TRIM5/ICAM1/PLSCR1/TRIM14/PVR/EIF2AK2/SLC3A2/NECTIN4/CD46/TYRO3/TPCN2/CHMP7/ITGB3/TMEM41B/ACE2/SLC52A2/SHFL/PIK3C2G/IFI16/N4BP1/CHMP6/ADAR/ITGB7/TRIM25/ITGAV/FURIN/ITGB6/IFITM2/TRIM22/STOM/VPS37B/PARP10/KPNA2/TFRC/SRPK1/LY6E/CLDN1/CD86/EPHA2/NECTIN2/HYAL2/PPIA/DAG1/CAV2/ZNFX1/P4HB/NEDD4/RNASEK/SMPD1/VPS18/ITGA5/ITGB5/VCP/CAV1/CHMP1B/TRIM27/SLC1A5/CHMP4C/SLC52A1/MORC2/RAB43/PKN2/ZC3HAV1/APOBEC3F/APOBEC3G/VPS37D/SCARB2
GOBP_DNA_DEPENDENT_DNA_REPLICATION 155 -0.4997185 -1.938897 0.0000013 0.0000599 0.0000483 2398 FEN1/LIG1/ATR/MCM4/MRE11/WRN/ALYREF/GINS4/LIG3/PRIMPOL/MMS22L/DBF4B/RRM1/ENDOG/FANCM/RFC3/ZGRF1/ZRANB3/GMNN/POLN/CDC7/EME1/GMNC/LRWD1/ORC6/WDHD1/FBXO5/DSCC1/POLD1/MCIDAS/GINS1/ORC1/CCNE1/ATAD5/BLM/DNA2/RAD51/RECQL4/GINS2/CDT1/E2F7/CCNE2/POLQ/TICRR/POLE2/MCM10/CDC45
GOBP_CELLULAR_RESPONSE_TO_LIPID 432 0.4132936 1.658054 0.0000013 0.0000602 0.0000486 2933 CXCL10/INSIG1/CXCL11/IL36G/CXCL9/LDLR/CMPK2/CXCL2/TNIP3/CXCL6/CXCL3/NTRK3/CXCL8/NPC1/CCL5/LBP/CXCL5/IL1B/KMO/CXCL1/NR2E3/LRP8/ZC3H12A/SCARB1/IRAK2/CSF3/NR4A3/EDN1/PF4V1/SERPINE1/ARID5A/CYP26B1/MYD88/ANKRD1/EPHA3/IL1A/CX3CL1/TNIP1/TNF/BMP6/TNFRSF1B/TICAM1/CD55/NFKBIA/NOS2/SOX9/SGK1/PCK2/CD274/HDAC6/LY96/PMEPA1/TNFAIP3/ERRFI1/TLR2/MEF2C/TRIM5/TLR4/PTAFR/TNIP2/ASS1/WBP2/INHBA/ADAM9/MSN/ADTRP/SELENOS/MYC/GJB3/IL36A/CYP1B1/LYN/ADCY5/TRIB1/PIM1/PPARGC1B/LDOC1/GFI1/COL1A1/NOD2/DAB2/CFTR/BCL10/EFNA5/ISL1/IRAK1/PTPN22/PHEX/VIM/DDIT4/SBNO2/MAPK3/ANXA1/ID3/TFPI/SYK/ALDH1A2/NDUFA13/SPON2/RIPK2/CAPN2/SRC/MGST1/MALT1/KDM4C/PLAA/AHR/MSX2/ZFP36/CLDN1/CD86/IL15/ZNF35/AKAP8/CEBPB/MAP2K3/NFKB1/NFKBIB/DAG1/IL18/DAB2IP/PID1/FAM210B/PAQR8/PGRMC2/NEDD4
GOBP_FATTY_ACID_METABOLIC_PROCESS 311 0.4509008 1.763816 0.0000014 0.0000644 0.0000520 1002 PLA2G3/PNPLA3/APOC1/ACAT2/FADS2/ELOVL6/MSMO1/FADS1/INSIG1/ACOT1/LIPC/ACLY/LIPG/LPIN1/SCD/MLXIPL/FASN/TRIB3/ALOXE3/ACSL1/PLA2G4C/SNCA/TBXAS1/NUDT8/HSD17B12/ACSL4/IL1B/ACOXL/PTGS2/CNR1/CEACAM1/ELOVL5/GGT5/NR4A3/EDN1/AACS/ALDH1L2/MFSD2A/ELOVL7/FA2H/ACADL/SOX9/ACACA/PCK2/ECH1/CYP4A22/LIPH
GOBP_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS 476 0.4043832 1.637201 0.0000014 0.0000647 0.0000522 2193 MVD/HMGCS1/ELOVL6/ACSS2/APOBEC3A/HMGCR/QPRT/ALDOB/ACOT1/ACLY/SLC2A6/MLXIPL/GFPT2/IDO1/ALDOC/CMPK2/HKDC1/MVK/DPYSL2/ENTPD8/ACSL1/XDH/IDO2/SNCA/NUDT8/HSD17B12/SLC25A1/ME1/KYNU/SLC5A8/ACSL4/PANK3/NT5E/PANK1/KMO/PDE4C/NUDT10/ELOVL5/NAMPT/NUDT11/APOBEC3B/TYMP/ADCY10/ELOVL7/PARP9/CARD11/NOS2/ACACA/GLRX/ENTPD2/CDA/GARS1/ENPP1/NUDT17/ELOVL1/ACOT2/MYC/ADCY4/HAAO/ADCY5/UCKL1/GALT/ACOT9/ANTKMT/GALK1/ENO3/GMPR/UXS1/PPARGC1A/PMM2/PTHLH/CTPS1/OGDH/GPAT4/NADK/UPP1/ACOT7/DDIT4/HACD2/PDE5A/PNP/ACSL5/PFKFB2/FAR2/PDE9A/ENTPD5/ELOVL4/GNE/NUDT16
GOBP_REGULATION_OF_VIRAL_PROCESS 134 0.5464678 1.936180 0.0000015 0.0000684 0.0000552 2642 APOBEC3A/ISG15/RSAD2/IFITM1/IFIT1/OAS3/OASL/ISG20/CXCL8/OAS1/MX1/CCL5/OAS2/BST2/IFIH1/APOBEC3B/IFITM3/LAMP3/TNIP1/TNF/TRIM31/STAT1/LGALS1/IFIT5/LGALS9/TRIM21/TRIM5/PLSCR1/TRIM14/EIF2AK2/TYRO3/SHFL/IFI16/N4BP1/ADAR/TRIM25/IFITM2/TRIM22/STOM/VPS37B/PARP10/KPNA2/SRPK1/ZFP36/LY6E/NECTIN2
GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE 253 0.4670600 1.790244 0.0000015 0.0000684 0.0000552 2818 PLA2G3/ZBP1/TNFAIP6/LDLR/IDO1/S100A12/MVK/NCF1/SNCA/CCL5/LBP/FOXP3/NT5E/IL1RL1/IL1B/CCN3/IL23A/PTGS2/CNR1/BIRC3/FYN/USP18/IFI35/SERPINE1/DUOXA2/ADAM8/MYD88/CXCL17/SEMA7A/CX3CL1/TNIP1/S100A8/IL1RL2/TNF/TNFRSF1B/LGALS1/NFKBIA/FANCA/SOCS3/CD47/SAA1/OSMR/TNFAIP3/TLR2/NMI/PTGES/TLR4/S100A9/KLF4/DUSP10/RHBDF2/CAMK2N1/PSMA6/SELENOS/C2CD4A/TYRO3/LYN/NFKBIZ/CD200/ACE2/NOD2/SPHK1/ETS1/FNDC4/C1QTNF3/DUOXA1/HLA-E/ISL1/CCN4/SBNO2/ANXA1/PTPN2/METRNL/SYK/FURIN/MAPK7/CASP5/TMSB4X/NLRP1/SRC/GPS2/SMPDL3B/ZFP36/IL15/LACC1/HYAL2/CTSC/IL1R1/TRADD/CEBPB/NFKB1/MFHAS1/IL18/RHBDD3/C3
GOBP_MEIOTIC_CHROMOSOME_SEGREGATION 72 -0.6186074 -2.143010 0.0000015 0.0000687 0.0000554 2118 M1AP/PSMC3IP/SMC4/CENPC/FANCM/RNF212/SMC2/FMN2/MAPK15/EME1/SYCP2/BRIP1/CCNE1/TRIP13/MAJIN/PTTG1/SGO2/ESPL1/CCNE2/TTK/PLK1/BUB1/NUF2/DMC1/NCAPH/SGO1/BUB1B/TOP2A
GOBP_REGULATION_OF_NUCLEAR_DIVISION 116 -0.5414930 -1.994872 0.0000016 0.0000703 0.0000567 1115 FBXO5/BMP7/ANAPC4/AURKA/MAD1L1/TRIP13/CCNB1/CDC25C/ZWINT/CDT1/RAD51AP1/CENPF/ESPL1/KIF20B/FBXO43/TTK/MAD2L1/NDC80/PLK1/NEK2/BUB1/DLGAP5/CDCA2/CDC20/IGF1/BUB1B/MKI67
GOBP_RESPONSE_TO_INTERFERON_GAMMA 104 0.5943803 2.044219 0.0000016 0.0000714 0.0000577 2005 CCL22/CCL4/CCL20/IFITM1/SNCA/KYNU/CCL5/BST2/NLRC5/SLC26A6/EDN1/IFITM3/GBP5/GBP2/CX3CL1/SOCS1/PARP9/TNF/CXCL16/STAT1/NOS2/STXBP1/GBP1/CD47/UBD/LGALS9/TLR2/NMI/TRIM21/TLR4/ASS1/PARP14/DAPK3/GCH1/MYC/STX4/CCL17/SP100/SHFL/MYO1C/CD40/GBP4/VIM/PTPN2
GOBP_DNA_REPAIR 489 -0.3636357 -1.580323 0.0000020 0.0000848 0.0000684 3928 CDC5L/BRCA2/NSMCE3/OGG1/HPF1/POLG2/FANCL/REV3L/NSD2/ERCC4/POLD3/SHPRH/PRKCG/RFC5/RPA3/BRME1/PPP4R3B/RUVBL1/ZCWPW1/RADX/TTC5/USP45/SPRTN/MSH6/FIGNL1/MSH2/UHRF1/TIMELESS/ZSWIM7/NSMCE1/NPM1/TRAIP/POT1/CRY2/ATRIP/BCCIP/FEN1/ATM/LIG1/RAD9B/PARPBP/ATR/MCM4/H2AX/UBE2T/POLR2I/C14orf39/MRE11/POLH/WRN/GTF2H5/SMC6/RAD52/HMGB1/RAD9A/RMI1/KMT5C/PDS5B/TEX264/DDB2/MC1R/NTHL1/NOP53/GINS4/MSH3/KDM4D/LIG3/POLI/PRIMPOL/MMS22L/CEP164/PMS1/RUVBL2/NEIL1/SLF1/EP400/WRAP53/MGMT/RRM1/PAXX/FANCM/TP73/ERCC1/RFC3/ABRAXAS1/HSF2BP/FMN2/ZRANB3/XRCC3/BRCA1/MRNIP/KIF22/POLN/CDC7/CETN2/EME1/RMI2/AXIN2/CHAF1B/IFFO1/NUDT1/EID3/WDHD1/EEPD1/HROB/POLD1/PCLAF/MCMDC2/BRIP1/FANCB/MUTYH/HMGB2/TRIP13/WAS/BLM/FTO/DNA2/RAD51/RECQL4/XRCC2/GINS2/PTTG1/RAD51AP1/RAD51AP2/CLSPN/CHD1L/POLQ/TICRR/CDK1/FOXM1/RAD54B/EXO1/RAD54L/ESCO2/CDCA5/NEIL3/POLE2/DMC1/CDC45/DTL
GOBP_MYELOID_LEUKOCYTE_ACTIVATION 161 0.5149084 1.872394 0.0000020 0.0000860 0.0000694 1518 PLA2G3/MT1G/LDLR/S100A12/CXCL6/CXCL8/ITGAM/SNCA/LAT2/CCL5/BATF3/LBP/BATF2/IL1RL1/THBS1/ZC3H12A/CNR1/CD177/NR4A3/IFI35/IL31RA/RELB/CAMK4/MYD88/ANXA3/CX3CL1/TNF/TICAM1/DYSF/STXBP1/ADGRE2/JUN/BATF/UNC13D/UBD/LGALS9/PLPP6/TLR2/NMI/IFNGR1/TLR4/PTAFR/TNIP2/JUND/PLSCR1/ITGB8/ADAM9/CSF1/STX4/LYN/CD200
GOBP_THIOESTER_METABOLIC_PROCESS 75 0.6348733 2.073751 0.0000021 0.0000865 0.0000698 2172 MVD/HMGCS1/ELOVL6/ACSS2/ACOT1/ACLY/MVK/ACSL1/SNCA/NUDT8/HSD17B12/SLC25A1/ACSL4/ELOVL5/ELOVL7/ACACA/ELOVL1/ACOT2/ACOT9/OGDH/GPAT4/ACOT7/HACD2/ACSL5/FAR2/ELOVL4
GOBP_FATTY_ACID_BIOSYNTHETIC_PROCESS 117 0.5647145 1.975376 0.0000020 0.0000865 0.0000698 1002 PLA2G3/APOC1/FADS2/ELOVL6/FADS1/INSIG1/LIPC/ACLY/LIPG/SCD/MLXIPL/FASN/TRIB3/ALOXE3/TBXAS1/HSD17B12/IL1B/PTGS2/CEACAM1/ELOVL5/EDN1/ELOVL7/FA2H/ACADL/ACACA/LIPH
GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 169 0.5074247 1.863321 0.0000025 0.0001037 0.0000836 2908 PLA2G3/RSAD2/ITGAM/CLCF1/LBP/FOXP3/IL1B/IL23A/SH2D1B/CD177/NR4A3/CAMK4/ARID5A/SEMA7A/KLK7/TNF/COLEC10/LAG3/TICAM1/CD55/NOS2/STXBP1/ADGRE2/UNC13D/LGALS9/DDX60/RAET1E/IL18R1/TLR4/PTAFR/CLEC7A/HLA-G/KLRD1/HLA-F/PVR/PTPRJ/DNAJB9/STX4/CD46/LYN/NFKBIZ/CADM1/NFKBID/GAB2/NOD2/BCL10/DHX58/CD40/HLA-E/PTPN22/ANXA1/F2RL1/SHLD1/SYK/SHLD2/HLA-B/HMOX1/SPON2/RIPK2/TRAF2/MALT1/SLC7A5/IL4R/TFRC/CD86/LACC1/NECTIN2/IL1R1/IL18/C3/SHLD3/FADD
GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 124 0.5566864 1.954282 0.0000025 0.0001046 0.0000844 2214 ZBP1/OASL/EREG/CCL5/LBP/NLRC5/IRF7/SH2D1B/FYN/IFI35/ADAM8/GBP5/EMILIN2/KLK7/PARP9/BMP6/LAG3/CD274/IKBKE/LY96/DDX60/NMI/RAET1E/TRIM5/TLR4/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/LYN/CADM1/MMP12/NOD2/IFI16/AKIRIN2/DHX58/HLA-E/USP27X/F2RL1/SYK/POLR3D/POLR3B
GOBP_MEIOTIC_CELL_CYCLE_PROCESS 154 -0.5030906 -1.951432 0.0000028 0.0001112 0.0000897 2118 M1AP/PSMC3IP/MYBL1/SMC4/CENPC/FANCM/ERCC1/CKS2/HSF2BP/RNF212/TDRD9/SMC2/FMN2/MAPK15/EME1/SYCP2/FBXO5/BRIP1/CCNE1/AURKA/TRIP13/MAJIN/CDC25C/RAD51/CDC25A/KIF18A/PTTG1/SGO2/RAD51AP1/ESPL1/CCNE2/FBXO43/TTK/NDC80/RAD54B/PLK1/CNTD1/RAD54L/CCNB2/BUB1/NUF2/DMC1/CDC20/NCAPH/SGO1/BUB1B/TOP2A/ASPM
GOBP_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE 99 0.5707806 1.937188 0.0000027 0.0001112 0.0000897 1503 PLA2G3/ZBP1/LDLR/IDO1/S100A12/SNCA/LBP/IL1RL1/IL1B/IL23A/PTGS2/CNR1/IFI35/SERPINE1/ADAM8/CX3CL1/TNIP1/S100A8/TNF/LGALS1/NFKBIA/CD47/OSMR/TLR2/NMI/TLR4/S100A9/CAMK2N1/C2CD4A/NFKBIZ
GOBP_RESPONSE_TO_PEPTIDE 380 0.4172853 1.658173 0.0000027 0.0001112 0.0000897 3482 PNPLA3/NTRK1/PCSK9/INSIG1/GRB14/LPIN1/SLC29A2/SLC2A4/TRIB3/NR4A1/CACNB1/MIR200A/EREG/KLF2/IGF2/IL1B/VCAM1/KLF11/HDAC9/PTGS2/CEACAM1/SOCS2/NAMPT/NR4A3/EDN1/FYN/FOXC2/EGR2/GDF15/STC2/MAP1B/CPEB2/RAB8B/SOCS1/AREG/TNF/STAT1/NFKBIA/PCK2/SOCS3/TNFAIP3/ERRFI1/TLR2/ADRB2/TLR4/ICAM1/TRIM16/ASS1/ENPP1/JUND/PRKCQ/GRB10/RARRES2/ANO1/SELENOS/MYC/CYP1B1/LYN/MMP12/IRS2/DDX11/LDOC1/KL/COL1A1/LGMN/STAT2/NOD2/MYO1C/MARS1/SESN2/MMP13/PTPN22/PHEX/VIM/ANXA1/PTPN2/TBC1D4/BCAR3/GOT1/SLC27A4/PIP4K2A/GPT/BCAR1/RIPK2/BTG1/NLRP1/SRC/STAT5A/NOD1/LPIN2/CACNA1A/CCND3/YWHAG/EGR1/SLC9A1/PIP4K2C/NDEL1/NCK1/GCNT1/NFKB1/DAG1/PIK3C2A/CAV2/SLC25A33/KBTBD2/ID1/PID1/ZBTB7B/MEAK7/CDC6/PNPT1/PTPN11/RAB12/SLC39A14/ZDHHC7/CAV1/MYO5A/GJB2/RANGAP1/CACNA2D1/GRB7/GNAI2/EPM2AIP1/PIP4K2B/ARHGEF2/EPRS1/CFLAR/SP1/RELA
GOBP_MONOCYTE_CHEMOTAXIS 39 0.7378864 2.134891 0.0000028 0.0001129 0.0000911 2031 S100A7/CXCL10/CCL22/CCL4/CCL20/S100A12/SLIT2/CCL5/CCN3/SERPINE1/CXCL17/CX3CL1/PDGFB/PTPRO/GREM1/LYN/FLT1/LGMN/CCL17/DUSP1/ANXA1/MOSPD2
GOBP_TISSUE_MIGRATION 268 0.4510338 1.735382 0.0000029 0.0001134 0.0000915 3102 HYAL1/FGFBP1/DLL4/PRSS3/SLIT2/NR4A1/FGF2/MIR200A/S100P/KDR/CCN3/HDAC9/THBS1/ZC3H12A/PTGS2/CEACAM1/SCARB1/EDN1/FOXC2/ANXA3/TNF/RHOB/VEGFA/STAT1/HBEGF/SOX9/JUN/FGF1/ACVRL1/HDAC6/LOXL2/DAAM2/ZEB2/PDGFB/TGFB2/MEF2C/PTP4A3/RRAS/GREM1/KLF4/ADAMTS9/FERMT1/DUSP10/ADAM9/ADTRP/ATOH8/MET/CYP1B1/EGF/CSNK2B/ITGB3/WNT7A/FSTL1/LGMN/GADD45A/BMPER/SP100/ETS1/PLPP3/AKT3/CD40/ADGRB1/SCG2/ARSB/SRF/ANXA1/GIPC1/CARD10/ADAM17/HDAC7/P2RX4/EPHB4/HMOX1/MAP4K4/BCAR1/ITGA3/TMSB4X/TGFBR1/SRC/SEMA3A/STAT5A/LPXN/TACSTD2/MAPRE2/EPHA2/MAP3K3/MAP2K3/PIK3C2A/GLUL/PLEKHG5/MYH9/DOCK5/RTN4/ID1/DAB2IP/FAP/SRPX2/JUP/PLCG1/SPARC/PTPN11/TGFBR2/GFUS
GOBP_MITOTIC_SPINDLE_ASSEMBLY 68 -0.6217962 -2.115041 0.0000034 0.0001346 0.0001086 1273 MAP10/RACGAP1/KIF11/KIF23/KIF15/PLK1/NEK2/KIF4A/TPX2/CDC20/KIFC1/MYBL2
GOBP_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY 355 0.4226818 1.677959 0.0000037 0.0001445 0.0001166 3521 NTRK1/S100A12/LPAR5/FOXP3/IL1B/NLRC5/RELN/LRP8/ZC3H12A/IRAK2/CSF3/EDN1/NLRP2/PPP2R5B/ADAM8/MYD88/ANXA3/CX3CL1/HES6/S100A8/TNF/TRIM31/VEGFA/RIPK3/TICAM1/CARD11/NFKBIA/FANCA/SGK1/IKBKG/FOXA2/BMP2/LGALS9/IKBKE/TNFAIP3/GLIS2/NFKBIE/TLR2/TRIM21/DDIT3/RTKN2/IL18R1/TRIM5/TLR4/CLEC7A/ENPP1/TRIM14/PRKCQ/GREM1/S100A9/KLF4/CHP1/EIF2AK2/DVL2/IRAK3/PSMA6/BHLHE40/CYP1B1/CDKN2A/TRAF1/TRIB1/CD200/PIM1/PPARGC1B/GFI1/NOD2/SPHK1/SP100/PELI1/PLPP3/CTNNBIP1/MDFI/PPARGC1A/BCL10/CD40/IRAK1/SLCO3A1/SRF/TRIM25/MAPK3/ID3/RNF31/SYK/CEBPG/CTH/HMOX1/MAP3K10/BCL3/RIPK2/TRIM22/TRAF2/FLNA/TMSB4X/MALT1/PRKCH/NOD1/FOSL1/RBCK1/PARP10/MSX2/TFRC/TRADD/RPS6KA4/NFKBIB/PPIA/IL18/ID1/DAB2IP/SAV1/JUP/TIRAP/TRAF5/DDRGK1/TWIST1/BRMS1/FLOT1/CAV1/MAP3K13/ARHGEF5/TRIM27/MAD2L2/COMMD7/ARHGEF2/CFLAR/RELA/ZC4H2/CRTC3/ADCY1
GOBP_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE 36 -0.7437320 -2.247465 0.0000048 0.0001809 0.0001459 758 RACGAP1/MAD1L1/CCNB1/CDT1/SPC24/SPAG5/KNL1/NDC80/CENPE/NEK2/NUF2/KIF2C/SGO1/SPC25
GOBP_CHRONIC_INFLAMMATORY_RESPONSE 12 0.9038447 2.038614 0.0000047 0.0001809 0.0001459 1307 IDO1/CCL5/FOXP3/VCAM1/THBS1/S100A8/TNF/VNN1/UNC13D/TNFAIP3/S100A9
GOBP_CELL_CYCLE_CHECKPOINT_SIGNALING 163 -0.4804304 -1.860500 0.0000048 0.0001809 0.0001459 864 BRIP1/ORC1/MAD1L1/E2F1/TRIP13/CCNB1/BLM/DNA2/ZWINT/CDT1/CENPF/CLSPN/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/BUB1/CDC45/DTL/GTSE1/BUB1B
GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS 284 0.4457777 1.722852 0.0000047 0.0001809 0.0001459 2419 TNFAIP6/FGL2/ISG15/LDLR/MVK/SLIT2/OAS3/RTN4R/MICA/FGF2/OAS1/FOXP3/NT5E/NLRC5/SEMA3B/CCN3/PLAU/THBS1/CEACAM1/C5AR2/SEMA3D/EDN1/FYN/USP18/SERPINE1/SERPINB2/CD34/CXCL17/SEMA7A/CX3CL1/TNF/TNFRSF1B/SOCS3/MICB/LGALS9/SAA1/SERPINB4/C1QTNF1/TNFAIP3/SERPINB9/NMI/TRIM21/PDGFB/PTPRO/PARP14/SH2B3/HLA-G/KLRD1/HLA-F/GREM1/KLF4/PLXNA3/DUSP10/RHBDF2/ADTRP/IRAK3/DUSP3/SELENOS/TYRO3/LYN/PHLDB2/TRIB1/PRKG1/CD200/MMP12/ARG2/STAT2/NOD2/FNDC4/IFI16/C1QTNF3/DHX58/HLA-E/ISL1/TRAFD1/DUSP1/ADAR/PTPN2/METRNL/SERPINF2/TFPI/SYK/CD9/FURIN/MAPK7/HLA-B/SERPINE2/SLC12A2/SRC/NPLOC4/SEMA3A/GPS2/INPP5F/SMPDL3B
GOBP_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS 172 0.4964253 1.826618 0.0000053 0.0001990 0.0001606 3598 PNPLA3/PCSK9/INSIG1/GRB14/LPIN1/SLC29A2/SLC2A4/TRIB3/IGF2/IL1B/HDAC9/CEACAM1/NAMPT/FOXC2/CPEB2/RAB8B/SOCS1/STAT1/PCK2/SOCS3/ERRFI1/ENPP1/PRKCQ/GRB10/RARRES2/SELENOS/MYC/IRS2/KL/MYO1C/MARS1/PTPN2/TBC1D4/BCAR3/GOT1/SLC27A4/PIP4K2A/GPT/BCAR1/SRC/LPIN2/CCND3/YWHAG/SLC9A1/PIP4K2C/NDEL1/NCK1/PIK3C2A/CAV2/SLC25A33/PID1/ZBTB7B/PTPN11/RAB12/SLC39A14/ZDHHC7/MYO5A/GRB7/GNAI2/PIP4K2B/EPRS1/CFLAR/SP1/IRS1/CAPN10/SHC1
GOBP_VIRAL_GENOME_REPLICATION 117 0.5528410 1.933843 0.0000067 0.0002469 0.0001992 1780 APOBEC3A/ISG15/RSAD2/IFITM1/IFIT1/OAS3/OASL/ISG20/CXCL8/OAS1/MX1/CCL5/OAS2/IFI27/BST2/IFIH1/ZC3H12A/APOBEC3B/IFITM3/TNIP1/TNF/IFIT5/PLSCR1/EIF2AK2/TMEM41B/SHFL/PIK3C2G/IFI16/N4BP1
GOBP_ADAPTIVE_IMMUNE_RESPONSE 285 0.4410831 1.707130 0.0000067 0.0002469 0.0001992 3323 EBI3/CD70/RSAD2/BACH2/MICA/LAT2/CLCF1/FOXP3/IL1RL1/IL1B/IRF7/ZC3H12A/IL23A/CEACAM1/SH2D1B/FYN/NFKB2/RELB/CAMK4/IL4I1/ARID5A/MYD88/TNFSF13B/TAP1/LAMP3/TNFRSF13C/TNF/TNFRSF1B/TAP2/LAG3/RIPK3/CD55/RFTN1/BATF/UNC13D/MICB/CD274/PRDM1/C4BPA/TNFAIP3/IL18R1/MEF2C/TLR4/ICAM1/CLEC7A/HLA-G/KLRD1/C1S/PRKCQ/HLA-F/PVR/DUSP10/TFE3/CD46/LYN/NFKBIZ/CADM1/BTN3A1/ARG2/HLA-C/HLA-DOB/NFKBID/NOD2/BCL10/CD40/IL7R/HLA-E/ANXA1/SHLD1/TRPM4/SYK/C8B/ADAM17/SHLD2/RAP1GAP/RNF168/HLA-B/BCL3/RIPK2/TREM1/MCOLN1/TRAF2/MALT1/IL4R/RAB27A/AHR/TFRC/CD86/RAPGEF3/NECTIN2/CTSC/IL1R1/SWAP70/IRF1/C2/IL18/C3/RAP1GAP2/SHLD3/FADD/SLC15A4/ZBTB7B/PLA2G4A/HLA-A/HLA-DMA/BTN3A3/FZD5/RNF19B/TRIM27/ADCY7/EMP2/MAD2L2/BTN3A2
GOBP_LEUKOCYTE_MEDIATED_IMMUNITY 258 0.4528763 1.741228 0.0000070 0.0002539 0.0002049 2945 PLA2G3/CD70/RSAD2/CXCL6/MICA/ITGAM/LAT2/CLCF1/FOXP3/IL1B/BST2/IRF7/IL23A/CEACAM1/SH2D1B/CD177/NR4A3/CAMK4/IL4I1/ARID5A/MYD88/ANXA3/TNF/TNFRSF1B/LAG3/RIPK3/TICAM1/CD55/NOS2/STXBP1/ADGRE2/RFTN1/BATF/UNC13D/LGALS9/C4BPA/SERPINB4/SERPINB9/RAET1E/IL18R1/TLR4/PTAFR/ICAM1/CLEC7A/ULBP1/HLA-G/KLRD1/C1S/HLA-F/PVR/STX4/CD46/LYN/ULBP3/CADM1/HLA-DOB/GAB2/NOD2/BCL10/CD40/IL7R/HLA-E/ULBP2/F2RL1/SHLD1/TRPM4/SYK/C8B/ADAM17/SHLD2/CEBPG/RNF168/HLA-B/HMOX1/SPON2/BCL3/TREM1/TRAF2/MALT1/IL4R/RAB27A/AHR/TUBB/TFRC/NECTIN2/CTSC/IL1R1/SWAP70/C2/IL18/C3/SHLD3/FADD/SLC15A4
GOBP_CELLULAR_RESPONSE_TO_PEPTIDE 286 0.4339842 1.678562 0.0000071 0.0002568 0.0002072 3604 PNPLA3/NTRK1/PCSK9/INSIG1/GRB14/LPIN1/SLC29A2/SLC2A4/TRIB3/NR4A1/CACNB1/MIR200A/KLF2/IGF2/IL1B/VCAM1/KLF11/HDAC9/CEACAM1/SOCS2/NAMPT/NR4A3/EDN1/FYN/FOXC2/GDF15/MAP1B/CPEB2/RAB8B/SOCS1/TNF/STAT1/PCK2/SOCS3/ERRFI1/ADRB2/TLR4/ICAM1/ASS1/ENPP1/PRKCQ/GRB10/RARRES2/ANO1/SELENOS/MYC/CYP1B1/LYN/IRS2/DDX11/LDOC1/KL/LGMN/NOD2/MYO1C/MARS1/PTPN22/VIM/PTPN2/TBC1D4/BCAR3/GOT1/SLC27A4/PIP4K2A/GPT/BCAR1/RIPK2/SRC/STAT5A/NOD1/LPIN2/CACNA1A/CCND3/YWHAG/SLC9A1/PIP4K2C/NDEL1/NCK1/NFKB1/PIK3C2A/CAV2/SLC25A33/ID1/PID1/ZBTB7B/CDC6/PTPN11/RAB12/SLC39A14/ZDHHC7/CAV1/MYO5A/GJB2/RANGAP1/CACNA2D1/GRB7/GNAI2/PIP4K2B/ARHGEF2/EPRS1/CFLAR/SP1/RELA/IRS1/CAPN10/SHC1/CRK
GOBP_DNA_GEOMETRIC_CHANGE 92 -0.5488463 -1.984623 0.0000079 0.0002843 0.0002294 1109 DSCC1/GINS1/MCMDC2/BRIP1/HMGB2/BLM/DNA2/RAD51/RECQL4/GINS2/CHD1L/POLQ/RAD54B/RAD54L/ERCC6L/CDC45/TOP2A
GOBP_POSITIVE_REGULATION_OF_CELL_DEATH 483 0.3884589 1.578424 0.0000081 0.0002882 0.0002325 3012 ZBP1/NTRK1/PCSK9/IL19/IFIT2/FZD9/IDO1/SLIT2/NR4A1/OLFM1/PNMA2/BBC3/MIR200A/ITGAM/SNCA/ASCL1/CCL5/PHLDA2/TNFRSF10A/KMO/HP/KLF11/THBS1/ZC3H12A/PTGS2/CNR1/NOX1/OSGIN1/PMAIP1/TNFRSF12A/FYN/DKK1/FOS/PLEKHN1/ADCY10/ADAM8/ANKRD1/EMILIN2/PML/ATF3/S100A8/TNF/RHOB/TNFRSF1B/RIPK3/LGALS1/NOS2/JUN/CD274/HDAC6/SPDEF/UBD/PEA15/BMP2/LGALS9/ALDH1A3/DDIT3/TGFB2/MEF2C/TLR4/ATF4/CCN1/CLEC7A/HLA-G/DUSP6/DAPK3/CDKN1A/S100A9/INHBA/INCA1/MYC/CYP1B1/CDKN2A/STK17B/LYN/AKAP12/PHLDA1/MAP3K9/ACER2/RNF122/GADD45A/DCUN1D3/SOX4/EEF1A2/BOK/BCL10/CD40/BID/DDIT4/USP27X/ANXA1/PTPN2/ID3/NFATC4/DLC1/PRELID1/SYK/PTRH2/ALDH1A2/SLC27A4/SQSTM1/HMOX1/MAP3K10/DAPK2/RIPK2/TRAF2/BTG1/CAPN2/TGFBR1/SRC/NOD1/FOSL1/FAS/IGFBP3/RBCK1/MSX2/EGR1/E2F3/TNFRSF10C/SYCE3/SLC9A1/UBE2Z/BAK1/CASP6/HYAL2/NCK1/CTSC/TRADD/TIGAR/SLFN11/DAB2IP/TNFRSF10B/FAP/MAP3K5/FADD/SAV1/ITGA6/RRP1B/CASP8/PPP2R1B/LATS2/PLCG1/SMPD1
GOBP_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY 35 -0.7317180 -2.193045 0.0000084 0.0002984 0.0002408 3340 DNAAF5/DNAI3/DRC1/DNAAF10/CFAP100/ZMYND10/ODAD4/DNAAF11/DNAAF3/DNAAF4/DNAL1/ODAD1/CCDC40/ODAD3/CFAP73/DAW1/TTC12/DNAI1/DNAH7/CCDC39/CCDC65/TEKT2/LRRC49/DNAI4/DNAI2/DNAAF8/DNAH1/DNAH5/ODAD2/DNAAF6/DNAAF1/DNAH2
GOBP_LEUKOCYTE_CELL_CELL_ADHESION 278 0.4418485 1.702533 0.0000085 0.0003000 0.0002420 3215 FGL2/EBI3/CD70/CERCAM/IDO1/TNFSF9/SLC39A8/SELL/CCL5/IGF2/FOXP3/NT5E/IL1B/VCAM1/ZC3H12A/IL23A/CEACAM1/CD177/NR4A3/FYN/PECAM1/IL4I1/ADAM8/CD83/TNFSF13B/IL1A/SOCS1/TNIP1/S100A8/IL1RL2/TNFRSF13C/TNF/LAG3/CARD11/LGALS1/CD55/VNN1/CD47/CD274/LGALS9/STK10/PTAFR/ICAM1/ASS1/HLA-G/PRKCQ/S100A9/KLF4/DUSP10/MSN/ADTRP/DUSP3/CD276/CD46/LYN/NFKBIZ/ARG2/HLA-DOB/TNFSF14/NFKBID/SELP/NOD2/ETS1/PELI1/SOX4/OLR1/BCL10/IL7R/HLA-E/IRAK1/MAP3K8/PTPN22/ITGB7/ANXA1/PTPN2/PDE5A/THY1/PNP/SYK/RIPK2/SLC7A1/SRC/MALT1/IL4R/TYK2/TFRC/CD86/IL15/NCK1/GCNT1/CEBPB/IRF1/IL18/FADD/ZBTB7B/ITGA5/HLA-A/BTN2A2/PTPN11/TGFBR2/SIRPA/GFUS/HLA-DMA/CAV1/CHST2/RUNX3
GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION 35 0.7370437 2.100867 0.0000087 0.0003019 0.0002436 2141 LUM/SERPINB7/FOXP3/THBS1/PTGS2/CD34/CX3CL1/LGALS9/TGFB2/FERMT1/ITGB8/CD46/CD200/LTBP1/CDH3/SERPINF2/ITGAV/FURIN/ITGB6
GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE 120 0.5508306 1.924112 0.0000091 0.0003133 0.0002528 2470 FGL2/ISG15/OAS3/MICA/OAS1/FOXP3/IL1RL1/NLRC5/ZC3H12A/CEACAM1/FYN/USP18/IL4I1/CD55/LGALS9/C4BPA/SERPINB4/TNFAIP3/SERPINB9/NMI/TRIM21/PARP14/HLA-G/KLRD1/HLA-F/DUSP10/RHBDF2/IRAK3/SELENOS/CD46/TYRO3/LYN/MMP12/ARG2/STAT2/NOD2/IFI16/DHX58/IL7R/FCRLB/HLA-E/TRAFD1/ADAR/ANXA1/PTPN2/SYK/FURIN/HLA-B/HMOX1/SRC/IL4R/AHR
GOBP_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE 54 0.6703952 2.078033 0.0000096 0.0003290 0.0002655 2005 ISG15/OAS3/MICA/OAS1/NLRC5/CEACAM1/USP18/LGALS9/SERPINB4/TNFAIP3/SERPINB9/NMI/TRIM21/PARP14/HLA-G/KLRD1/HLA-F/DUSP10/IRAK3/TYRO3/MMP12/STAT2/IFI16/DHX58/HLA-E/TRAFD1/ADAR/PTPN2
GOBP_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS 17 -0.8507884 -2.171924 0.0000099 0.0003358 0.0002709 945 ECRG4/ANAPC4/CDC20B/PLK1/CDC20/UBE2C
GOBP_ENDOTHELIAL_CELL_MIGRATION 196 0.4770946 1.774880 0.0000101 0.0003431 0.0002768 3031 FGFBP1/DLL4/PRSS3/SLIT2/NR4A1/FGF2/MIR200A/S100P/KDR/CCN3/HDAC9/THBS1/ZC3H12A/PTGS2/CEACAM1/SCARB1/EDN1/FOXC2/ANXA3/TNF/RHOB/VEGFA/STAT1/FGF1/ACVRL1/LOXL2/PDGFB/MEF2C/PTP4A3/RRAS/GREM1/KLF4/ADAMTS9/ADTRP/ATOH8/MET/CYP1B1/EGF/CSNK2B/ITGB3/WNT7A/FSTL1/LGMN/GADD45A/BMPER/SP100/ETS1/PLPP3/AKT3/CD40/ADGRB1/SCG2/SRF/ANXA1/GIPC1/CARD10/ADAM17/HDAC7/P2RX4/EPHB4/HMOX1/BCAR1/TMSB4X/TGFBR1/STAT5A/LPXN/EPHA2/MAP3K3/MAP2K3/PIK3C2A/GLUL/PLEKHG5/MYH9/ID1/DAB2IP/FAP/SRPX2/JUP/PLCG1/SPARC
GOBP_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION 19 0.8294400 2.071200 0.0000108 0.0003642 0.0002939 2138 LUM/SERPINB7/FOXP3/THBS1/PTGS2/CD34/CX3CL1/LGALS9/FERMT1/CD46/CD200/SERPINF2/FURIN
GOBP_DNA_REPLICATION_INITIATION 37 -0.7109489 -2.167754 0.0000110 0.0003683 0.0002972 1540 GMNN/GMNC/LRWD1/ORC6/MCIDAS/ORC1/CCNE1/CDT1/CCNE2/TICRR/MCM10/CDC45
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION 99 -0.5320265 -1.937226 0.0000113 0.0003744 0.0003021 1641 MAPK15/CENPJ/MTBP/CDC7/STOX1/FBXO5/EZH2/ANAPC4/CCNB1/ATAD5/NANOGP8/CDC25C/CDC25A/CDT1/ESPL1/FAM83D/CDK1/CDCA5/DLGAP5/RRM2/DTL/UBE2C
GOBP_REGULATION_OF_CELL_CELL_ADHESION 345 0.4152753 1.639386 0.0000119 0.0003905 0.0003151 3215 MUC21/FGL2/EBI3/CD70/IDO1/PLAUR/TNFSF9/CCL5/IGF2/FOXP3/IL1B/VCAM1/ZC3H12A/IL23A/CEACAM1/NR4A3/FYN/IL4I1/ADAM8/CD83/TNFSF13B/EMILIN2/IL1RN/IL1A/CX3CL1/SOCS1/IL1RL2/TNFRSF13C/TNF/CEACAM6/BMP6/VEGFA/LAG3/CARD11/LGALS1/CD55/VNN1/CD47/CD274/FOXA2/BMP2/LGALS9/PIEZO1/FSTL3/C1QTNF1/FXYD5/FUT3/PTAFR/ASS1/SH2B3/HLA-G/PRKCQ/KLF4/TENM3/PODXL/DUSP10/ADTRP/DUSP3/CD276/CD46/LYN/NFKBIZ/PRKG1/ARG2/HLA-DOB/TNFSF14/NFKBID/SELP/NOD2/ETS1/PELI1/SOX4/PLPP3/BCL10/EFNA5/IL7R/HLA-E/IRAK1/MAP3K8/PTPN22/ANXA1/PTPN2/SERPINF2/TJP1/PDE5A/ABCA12/THY1/PNP/SYK/CD9/MAPK7/RIPK2/SERPINE2/SLC7A1/SRC/MALT1/IL4R/TYK2/TFRC/CD86/IL15/NCK1/SWAP70/CEBPB/IRF1/WNT4/IL18/EPCAM/CDH1/FADD/ZBTB7B/MYADM/HLA-A/BTN2A2/PTPN11/TGFBR2/JAK1/SIRPA/HLA-DMA/PDPN/FLOT1/CAV1/CHST2/RUNX3
GOBP_RIBOSE_PHOSPHATE_METABOLIC_PROCESS 330 0.4233081 1.669969 0.0000124 0.0004036 0.0003256 3319 MVD/HMGCS1/ELOVL6/ACSS2/HMGCR/ALDOB/ACOT1/ACLY/SLC2A6/MLXIPL/ALDOC/HKDC1/MVK/ACSL1/XDH/SNCA/NUDT8/HSD17B12/SLC25A1/ACSL4/PANK3/NT5E/PANK1/PDE4C/NUDT10/ELOVL5/NUDT11/ADCY10/ELOVL7/G6PD/CARD11/ACACA/CDA/ENPP1/ELOVL1/ACOT2/MYC/ADCY4/ADCY5/UCKL1/ACOT9/ANTKMT/GALK1/ENO3/PPARGC1A/PTHLH/CTPS1/OGDH/GPAT4/UPP1/ACOT7/DDIT4/HACD2/PDE5A/PNP/ACSL5/PFKFB2/FAR2/PDE9A/ENTPD5/ELOVL4/NUDT16/BPGM/GUCY1A2/PMVK/TMSB4X/PDE8A/DGAT1/EPHA2/TJP2/DIP2A/TIGAR/FOXK2/NT5C2/GDA/SULT1B1/PRXL2C/PID1/PDHB/ADPGK/HK2/FLCN/PFKP/GUK1/HACD1/VCP/DLAT/FITM2/FAR1/ALDOA/DHODH/ADCY7/PPT1
GOBP_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION 81 -0.5671035 -2.016873 0.0000125 0.0004057 0.0003274 758 MAD1L1/TRIP13/CCNB1/ZWINT/PTTG1/CDT1/CENPF/ESPL1/TTK/MAD2L1/NDC80/PLK1/BUB1/BUB1B/TOP2A
GOBP_CILIUM_MOVEMENT 137 -0.4931120 -1.860512 0.0000133 0.0004280 0.0003454 3461 KIF9/BBS4/CFAP20/DNAAF5/DNAI3/ADCY3/DRC1/CATSPER2/SLC26A8/SPAG6/CFAP100/ZMYND10/ODAD4/CFAP91/ARMC2/TTC29/CFAP251/DNAAF11/TTLL9/KIF27/CFAP47/AQP4/CFAP46/HOATZ/SPA17/TTLL3/BBS2/CFAP69/DNAAF4/CFAP58/ENO4/ODAD1/CCDC40/GAS2L2/CFAP52/CFAP54/RSPH9/ZBBX/DRC7/ODAD3/SPAG17/DZIP1/CFAP73/CFAP157/NME5/DAW1/TTC12/DNAI1/DNAH7/IQCG/SPEF2/CCDC39/DPCD/SPAG16/SLC22A16/CFAP61/TEKT3/ROPN1L/ROPN1B/CCDC65/HYDIN/CFAP206/TEKT2/TEKT1/RFX3/DNAH9/TTC21A/TCTE1/DNAI4/CFAP45/CFAP65/NEK10/DNAI2/CFAP44/TEKT4/MNS1/TEKT5/DNAH1/DNAH5/CFAP70/CFAP43/CFAP221/ODAD2/DNAAF6/DNAAF1/CFAP53/TTLL6/PLTP/CATSPERD/MEIG1/EPPIN
GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 90 0.5850602 1.960550 0.0000137 0.0004395 0.0003546 2005 FGL2/ISG15/OAS3/MICA/OAS1/FOXP3/NLRC5/CEACAM1/USP18/IL4I1/MICB/LGALS9/SERPINB4/TNFAIP3/SERPINB9/NMI/TRIM21/PARP14/HLA-G/KLRD1/HLA-F/DUSP10/IRAK3/TYRO3/TRIB1/MMP12/ARG2/STAT2/IFI16/DHX58/HLA-E/TRAFD1/ADAR/PTPN2
GOBP_BLOOD_VESSEL_MORPHOGENESIS 487 0.3869370 1.574846 0.0000146 0.0004622 0.0003730 3125 S100A7/CXCL10/HYAL1/THSD7A/FGFBP1/DLL4/LDLR/CCR3/SLIT2/NR4A1/CXCL8/FGF2/XDH/KDR/EREG/KLF2/IL1B/ADM2/CCN3/HDAC9/THBS1/ZC3H12A/PTGS2/CEACAM1/YJEFN3/NOX1/STRA6/EDN1/TNFRSF12A/FOXC2/CLIC4/TYMP/ANGPTL4/SERPINE1/ADAM8/CD34/CXCL17/EMILIN2/IL1A/ANXA3/CX3CL1/PML/TNF/RHOB/FMNL3/VEGFA/WARS1/STAT1/MMP19/JUN/FGF1/ACVRL1/LOXL2/VASH2/TNFAIP2/PRDM1/TNFAIP3/ENG/EIF2AK3/TGFB2/CCN1/ADIPOR2/HLA-G/RRAS/RNF213/GREM1/KLF4/ADAMTS9/MFGE8/ITGB8/ADTRP/CYP1B1/EGF/NRCAM/ESM1/PLCD3/FLT1/ITGB3/WNT7A/COL22A1/GADD45A/BMPER/CEMIP2/SPHK1/SP100/ETS1/SOX4/AKT3/CD40/ADGRB1/ISL1/HSPG2/SCG2/COL8A2/SRF/ANXA1/SERPINF2/TJP1/ITGAV/CARD10/NFATC4/NIBAN2/MYDGF/THY1/SYK/NTRK2/HDAC7/TGFBI/MMP14/MAPK7/EPHB4/ADAMTS1/HMOX1/BTG1/SLC12A2/FLNA/TGFBR1/CALD1/TGFA/LRG1/F3/BAK1/JUNB/RAPGEF3/EPHA2/MAP3K3/WNT4/ACTG1/DAG1/PIK3C2A/GLUL/ECM1/IL18/MYH9/C3/ID1/DAB2IP/FAP/HK2/SARS1/CASP8/SRPX2/JUP/PLCG1/PKNOX1/ITGA5/SHB/SPARC/TGFBR2/JAK1/C1GALT1/ADGRG1/TWIST1
GOBP_ISOPRENOID_BIOSYNTHETIC_PROCESS 26 0.7744146 2.066951 0.0000154 0.0004853 0.0003916 1075 MVD/HMGCS1/LSS/FDPS/HMGCR/IDI1/MVK/SRD5A3/BCO1/ALDH1A3
GOBP_AMEBOIDAL_TYPE_CELL_MIGRATION 364 0.4024128 1.598766 0.0000155 0.0004853 0.0003916 3761 HYAL1/FGFBP1/DLL4/PRSS3/SLIT2/SLC8A1/NR4A1/FGF2/MIR200A/S100P/KDR/SEMA3B/CCN3/HDAC9/THBS1/ZC3H12A/PTGS2/CEACAM1/SCARB1/SEMA3D/EDN1/FOXC2/ALX1/SEMA7A/ANXA3/PML/TNF/RHOB/VEGFA/STAT1/HBEGF/SOX9/JUN/FGF1/ACVRL1/HDAC6/LOXL2/DAAM2/ZEB2/ENG/PDGFB/TGFB2/MEF2C/PTP4A3/RRAS/GREM1/KLF4/ADAMTS9/FERMT1/DUSP10/ADAM9/ADTRP/ATOH8/MET/CYP1B1/EGF/AKAP12/CSNK2B/ITGB3/WNT7A/GNA12/FSTL1/LGMN/GADD45A/BMPER/SP100/ETS1/PLPP3/AKT3/CD40/RFFL/ADGRB1/ISL1/SCG2/ARSB/ITGB7/SRF/ANXA1/GIPC1/CARD10/TPBG/ADAM17/HDAC7/P2RX4/EPHB4/ILK/HMOX1/MAP4K4/BCAR1/ITGA3/TMSB4X/TGFBR1/CAP1/SRC/SEMA3A/STAT5A/LPXN/TACSTD2/MAPRE2/SYDE1/SEMA3C/EPHA2/HYAL2/MAP3K3/MAP2K3/PIK3C2A/GLUL/PLEKHG5/MYH9/DOCK5/RTN4/ID1/DAB2IP/FAP/ITGB4/SRPX2/JUP/PLCG1/SPARC/PTPN11/TGFBR2/GFUS/TWIST1/ACTA2/TESK1/PLK2/EMP2/RAB25/HAS2/IQGAP1/SP1/PKN2/PLEC/PFN1/KRT16/MACF1/SGPL1/AMOTL2/BMP4/RIC8A/RHOA/BMPR2/RAC1/TIMP1/SDC4
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS 197 -0.4453124 -1.785554 0.0000172 0.0005343 0.0004311 2173 SLF1/SOX15/SMPD3/RRM1/PRKCE/CEP120/SASS6/CIT/XRCC3/MAPK15/CENPJ/MTBP/DRD2/CDC7/CDC14A/MAP10/STOX1/RACGAP1/FBXO5/EZH2/ANAPC4/AURKA/MAD1L1/CCNB1/ATAD5/NANOGP8/CDC25C/CDC25A/KIF23/CDT1/RAD51AP1/ESPL1/E2F7/KIF14/KIF20B/FAM83D/MAD2L1/SPAG5/CDK1/NDC80/PLK4/CDCA5/DLGAP5/IGF1/RRM2/DTL/UBE2C
GOBP_RESPONSE_TO_INSULIN 210 0.4632356 1.746000 0.0000173 0.0005343 0.0004311 3598 PNPLA3/PCSK9/INSIG1/GRB14/LPIN1/SLC29A2/SLC2A4/TRIB3/IGF2/IL1B/HDAC9/CEACAM1/NAMPT/FOXC2/EGR2/CPEB2/RAB8B/SOCS1/STAT1/PCK2/SOCS3/ERRFI1/TLR2/ENPP1/PRKCQ/GRB10/RARRES2/SELENOS/MYC/LYN/IRS2/KL/MYO1C/MARS1/SESN2/PTPN2/TBC1D4/BCAR3/GOT1/SLC27A4/PIP4K2A/GPT/BCAR1/SRC/LPIN2/CCND3/YWHAG/EGR1/SLC9A1/PIP4K2C/NDEL1/NCK1/GCNT1/PIK3C2A/CAV2/SLC25A33/KBTBD2/PID1/ZBTB7B/MEAK7/PTPN11/RAB12/SLC39A14/ZDHHC7/MYO5A/GRB7/GNAI2/EPM2AIP1/PIP4K2B/EPRS1/CFLAR/SP1/IRS1/CAPN10/SHC1
GOBP_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION 141 -0.4778623 -1.815462 0.0000176 0.0005401 0.0004358 3640 ALMS1/PARD6G/MAP9/BBS4/GCC2/NPM1/PARD6A/CHORDC1/CEP250/HAUS4/CCDC57/CEP44/CEP76/KIAA1614/RBM14/CEP135/HAUS1/SSX2IP/CEP295/FOXJ1/CHD3/STIL/BCAS3/DEUP1/HAUS5/MPDZ/CCDC61/DZIP1/PCM1/CEP120/TMEM67/CETN3/SASS6/CCP110/XRCC3/BRCA1/CENPJ/WDR62/CEP152/CETN2/CEP68/MDM1/MCIDAS/PCLAF/CCNF/CCDC78/KIF11/AURKA/CROCC/XRCC2/CDK1/NDC80/HEPACAM2/PLK1/NEK2/PLK4/SGO1
GOBP_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS 258 -0.4061857 -1.652553 0.0000198 0.0006029 0.0004865 1693 XRCC3/JADE1/BRCA1/MTBP/MRNIP/EME1/GPNMB/MDM1/FBXO5/STK33/GJC2/BMP7/EZH2/BRIP1/CCNF/ORC1/GPER1/MAD1L1/E2F1/TRIP13/CCNB1/BLM/DNA2/ZWINT/PTTG1/CDT1/CENPF/CLSPN/ESPL1/E2F7/FBXO43/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/NEK2/BUB1/CDC45/DTL/GTSE1/BUB1B
GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION 78 0.5964776 1.958688 0.0000201 0.0006101 0.0004923 866 APOBEC3A/ISG15/RSAD2/IFITM1/IFIT1/OAS3/OASL/ISG20/CXCL8/OAS1/MX1/CCL5/OAS2/BST2/IFIH1/APOBEC3B/IFITM3/TNIP1/TNF/IFIT5
GOBP_NEUTRAL_LIPID_METABOLIC_PROCESS 93 0.5619551 1.895567 0.0000205 0.0006182 0.0004988 1290 PNPLA3/APOC1/PCSK9/INSIG1/LIPC/LIPG/LPIN1/LDLR/ACSL1/SNCA/SCARB1/MFSD2A/DGKI/PCK2/LIPH/APOBR/LIPE/GPAT3
GOBP_LYMPHOCYTE_CHEMOTAXIS 35 0.7246645 2.065581 0.0000207 0.0006188 0.0004993 1714 S100A7/CXCL10/CXCL11/CCL22/CCL4/CCL20/CCL5/ADAM8/CX3CL1/CXCL16/SAA1/OXSR1/TNFSF14/CCL17/SLC8B1
GOBP_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS 230 0.4493609 1.709796 0.0000211 0.0006285 0.0005071 3396 PNPLA3/MVD/HMGCS1/FDPS/FADS1/IDI1/LPIN1/MVK/PLA2G4C/FGF2/LCAT/SRD5A3/SOCS2/ABHD4/MFSD2A/PCYT2/SOCS1/SELENOI/IDH1/SOCS3/LIPH/PI4K2A/PDGFB/PISD/PLSCR1/GPAT3/PIGW/CHP1/ITPKC/SERINC4/LPCAT1/PIK3C2G/GPAT4/DHDDS/PIP4K2A/PIK3C2B/PMVK/CAPN2/HEXB/INPP5F/PIP4K2C/LPCAT4/MBOAT7/PIK3C2A/PGAP4/PIGA/CISH/TTC7A/PLA2G4A/SYNJ2/SGMS1/PIGZ/FITM2/PITPNM2/FAR1/PIGS/ABHD5/PIP4K2B/INPP1/PTDSS1
GOBP_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE 101 0.5544740 1.892903 0.0000213 0.0006304 0.0005087 3025 ZBP1/EREG/CCL5/LBP/NLRC5/IRF7/SH2D1B/FYN/IFI35/ADAM8/GBP5/PARP9/LAG3/IKBKE/NMI/RAET1E/TRIM5/TLR4/CLEC7A/HLA-G/KLRD1/PLSCR1/HLA-F/PVR/LYN/CADM1/MMP12/NOD2/IFI16/AKIRIN2/HLA-E/USP27X/SYK/POLR3D/POLR3B/SRC/CASP6/NECTIN2/ZNFX1/FADD/SLC15A4/TIRAP
GOBP_ALPHA_BETA_T_CELL_PROLIFERATION 31 0.7440556 2.065858 0.0000222 0.0006519 0.0005260 3060 EBI3/IL23A/CD55/CD274/LGALS9/ARG2/MAPK8IP1/HLA-E/PTPN22/ELF4/SYK/RIPK2/TYK2/IL15/IRF1/IL18/ZBTB7B/HLA-A/TGFBR2
GOBP_WOUND_HEALING 337 0.4059146 1.601884 0.0000229 0.0006679 0.0005390 3947 SPRR3/PLAUR/SERPINC1/FGF2/KDR/SLC7A11/EREG/PLAU/THBS1/CEACAM1/SCARB1/TFPI2/PROCR/PEAR1/EDN1/TNFRSF12A/FOXC2/PF4V1/SERPINE1/VWF/SERPINB2/CD34/DGKI/EMILIN2/IL1A/CX3CL1/OCLN/S100A8/TNF/VEGFA/DYSF/HBEGF/STXBP1/CLDN4/FGF1/ACVRL1/FOXA2/ENTPD2/RAP2B/SAA1/C1QTNF1/TNFAIP3/PDGFB/TGFB2/TLR4/CCN1/ADIPOR2/VCL/MYL9/CLEC7A/SH2B3/PLSCR1/PRKCQ/CDKN1A/FERMT1/LCP1/ADTRP/VKORC1/DUOX2/TYRO3/LYN/PHLDB2/PRKG1/CHMP7/ITGB3/WNT7A/MMP12/GNA12/BLOC1S3/COL1A1/SELP/CD151/PLPP3/ITPK1/CSRP1/CD40/ANXA8/CHMP6/MYL12A/CCN4/CDH3/SRF/ANXA1/F2RL1/KRT6A/SERPINF2/TFPI/SYK/ADAM17/CD9/TPM1/ITGB6/ILK/HMOX1/DCBLD2/SERPINE2/SLC12A2/FLNA/TGFBR1/SRC/PAFAH2/RHOC/TGFA/RAB27A/MSX2/F3/NRG1/CNN2/CLDN1/ACTB/C6orf89/WNT4/ACTG1/PPIA/DAG1/MYH9/FAP/MAP3K5/PLA2G4A/SMPD1/ITGA5/TGFBR2/GRHL3/PDPN/ACTA2/CAV1/CHMP1B/ST3GAL4/CHMP4C/EXT1/F12/CFLAR/ABAT/PLEC/PDGFRA/MACF1/CRK/HRAS/ALOX5/RHOA/PPL/TIMP1/SDC4/B4GALT1/SMAD3/SERPINA1/EVPL/HIF1A/PPARD/ACTN1/MRTFA/MYOF/CHMP2B/TEC/DST/SYT7/TSKU
GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION 207 0.4669593 1.756843 0.0000236 0.0006858 0.0005534 3060 PLA2G3/TNFAIP6/FGL2/TNFSF9/LIF/EVI2B/FOXP3/IRF7/ZC3H12A/IL23A/CEACAM1/LRRC17/FOS/PRXL2A/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/SOCS1/IL1RL2/TNF/LAG3/CARD11/LGALS1/GPR68/VNN1/FANCA/LGALS9/FSTL3/PRDM1/TLR4/HLA-G/INHBA/DUSP10/TFE3/MYC/IL34/CSF1/CD46/LYN/NFKBIZ/TRIB1/PPARGC1B/IL15RA/NFKBID/SOX4/CTNNBIP1/TMEM176A/IL7R/KLF10/TOX/ZEB1/ANXA1/PTPN2/PRELID1/PNP/SYK/MMP14/TMEM176B/HLA-B/RIPK2/MALT1/IL4R/CD86/IL15/ZBTB46/CEBPB/IRF1/SOS2/IL18/FADD/ZBTB7B/CASP8/BTN2A2/TGFBR2
GOBP_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA 85 0.5815217 1.943007 0.0000271 0.0007799 0.0006293 2005 CCL22/CCL4/CCL20/CCL5/NLRC5/SLC26A6/EDN1/GBP5/GBP2/CX3CL1/SOCS1/PARP9/TNF/STAT1/NOS2/STXBP1/GBP1/CD47/LGALS9/TLR2/NMI/TLR4/ASS1/PARP14/DAPK3/MYC/STX4/CCL17/SP100/MYO1C/GBP4/VIM/PTPN2
GOBP_LYMPHOCYTE_MIGRATION 72 0.6032070 1.959050 0.0000287 0.0008214 0.0006628 2149 S100A7/CXCL10/CXCL11/CCL22/CCL4/CCL20/CCL5/ADAM8/CX3CL1/CXCL16/RIPK3/ARTN/SAA1/STK10/SPNS2/ICAM1/OXSR1/MSN/ADTRP/CD200/TNFSF14/CCL17/SLC8B1/ITGB7/ADAM17/XG
GOBP_RESPONSE_TO_PEPTIDE_HORMONE 304 0.4243352 1.654817 0.0000299 0.0008510 0.0006866 3604 PNPLA3/PCSK9/INSIG1/GRB14/LPIN1/SLC29A2/SLC2A4/TRIB3/NR4A1/EREG/IGF2/IL1B/HDAC9/PTGS2/CEACAM1/SOCS2/NAMPT/NR4A3/EDN1/FOXC2/EGR2/GDF15/STC2/MAP1B/CPEB2/RAB8B/SOCS1/AREG/STAT1/PCK2/SOCS3/ERRFI1/TLR2/TRIM16/ASS1/ENPP1/JUND/PRKCQ/GRB10/RARRES2/SELENOS/MYC/CYP1B1/LYN/IRS2/KL/COL1A1/STAT2/MYO1C/MARS1/SESN2/PHEX/ANXA1/PTPN2/TBC1D4/BCAR3/GOT1/SLC27A4/PIP4K2A/GPT/BCAR1/BTG1/SRC/STAT5A/LPIN2/CCND3/YWHAG/EGR1/SLC9A1/PIP4K2C/NDEL1/NCK1/GCNT1/NFKB1/DAG1/PIK3C2A/CAV2/SLC25A33/KBTBD2/PID1/ZBTB7B/MEAK7/CDC6/PNPT1/PTPN11/RAB12/SLC39A14/ZDHHC7/CAV1/MYO5A/GJB2/RANGAP1/GRB7/GNAI2/EPM2AIP1/PIP4K2B/EPRS1/CFLAR/SP1/RELA/IRS1/CAPN10/SHC1/CRK
GOBP_MICROTUBULE_BUNDLE_FORMATION 106 -0.5156886 -1.884766 0.0000305 0.0008628 0.0006962 3340 DNAAF5/DNAI3/DRC1/NCKAP5L/TPPP3/SPAG6/DNAAF10/CFAP100/ZMYND10/ODAD4/LRGUK/CFAP91/ARMC2/FOXJ1/DNAAF11/DNAAF3/CFAP47/CFAP46/HOATZ/TTLL3/BBS2/CFAP69/DNAAF4/DNAL1/CFAP58/CCDC66/ODAD1/CCDC40/GAS2L2/DNAJB13/RSPH9/DRC7/ODAD3/SPAG17/CFAP73/CFAP157/CC2D2A/DAW1/TTC12/DNAI1/RSPH1/DNAH7/IQCG/SPEF2/CCDC39/SPAG16/CCDC65/HYDIN/CFAP206/TEKT2/LRRC49/DNAI4/CFAP65/DNAI2/CFAP74/CFAP44/MNS1/DNAAF8/DNAH1/DNAH5/CFAP43/ODAD2/DNAAF6/RP1/DNAAF1/TTLL6/DNAH2/NCKAP5/MEIG1/PSRC1/CAPN6/PLK1/KIF20A
GOBP_REGULATION_OF_LYMPHOCYTE_ACTIVATION 335 0.4088649 1.612035 0.0000311 0.0008742 0.0007054 3215 FGL2/EBI3/CD70/THEMIS2/IDO1/TNFSF9/MICA/CCL5/CLCF1/IGF2/FOXP3/IL1B/VCAM1/ZC3H12A/IL23A/CEACAM1/FYN/CAMK4/IL4I1/ADAM8/CYP26B1/MYD88/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/TNFRSF13C/TNFRSF1B/LAG3/RIPK3/TICAM1/CARD11/LGALS1/CD55/VNN1/FANCA/CD47/CD274/LGALS9/PRDM1/TNFAIP3/MEF2C/TLR4/TNIP2/CLEC7A/HLA-G/PRKCQ/HLA-F/CDKN1A/INHBA/DUSP10/DUSP3/CD276/CD46/TYRO3/LYN/NFKBIZ/IRS2/ARG2/IL15RA/BLOC1S3/HLA-DOB/TNFSF14/NFKBID/MAPK8IP1/NOD2/PELI1/SOX4/BCL10/CD40/IL7R/HLA-E/MAP3K8/PTPN22/TOX/ZEB1/ANXA1/PTPN2/SHLD1/PRELID1/PDE5A/THY1/PNP/SYK/SHLD2/MMP14/RIPK2/SLC7A1/SRC/MALT1/IL4R/TYK2/AHR/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/SOS2/IL18/RHBDD3/SHLD3/FADD/SLC15A4/ZBTB7B/TIRAP/HLA-A/BTN2A2/PTPN11/TGFBR2/SIRPA/HLA-DMA/SH3KBP1/CAV1/RUNX3
GOBP_REGULATION_OF_EPITHELIAL_CELL_MIGRATION 205 0.4603584 1.726160 0.0000329 0.0009198 0.0007422 3102 HYAL1/FGFBP1/DLL4/SLIT2/FGF2/MIR200A/KDR/HDAC9/THBS1/ZC3H12A/PTGS2/CEACAM1/SCARB1/EDN1/FOXC2/ANXA3/TNF/RHOB/VEGFA/HBEGF/SOX9/JUN/FGF1/ACVRL1/HDAC6/PDGFB/TGFB2/MEF2C/RRAS/KLF4/ADAMTS9/DUSP10/ADAM9/ATOH8/MET/EGF/CSNK2B/ITGB3/WNT7A/LGMN/GADD45A/BMPER/SP100/ETS1/PLPP3/AKT3/CD40/ADGRB1/ARSB/ANXA1/CARD10/ADAM17/HDAC7/P2RX4/HMOX1/MAP4K4/BCAR1/ITGA3/TMSB4X/SRC/SEMA3A/STAT5A/TACSTD2/MAPRE2/EPHA2/MAP3K3/MAP2K3/PIK3C2A/GLUL/DOCK5/RTN4/DAB2IP/SRPX2/JUP/PLCG1/SPARC/TGFBR2/GFUS
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION 102 0.5494612 1.881490 0.0000353 0.0009807 0.0007913 2286 S100A7/CXCL10/CCL4/CCL20/CXCL8/CCL5/LBP/THBS1/IL23A/EDN1/SERPINE1/ADAM8/CXCL17/IL1A/CX3CL1/TNF/VEGFA/CD47/LGALS9/PTAFR/ICAM1/OXSR1/RARRES2/IL34/CSF1/TNFSF14/SELP/LGMN/MAPK3/F2RL1/MOSPD2/THY1/ADAM17/XG/MMP14/P2RX4/DAPK2
GOBP_MITOTIC_CELL_CYCLE_CHECKPOINT_SIGNALING 124 -0.4910530 -1.830207 0.0000375 0.0010332 0.0008337 828 XRCC3/BRCA1/MRNIP/EME1/STK33/ORC1/MAD1L1/TRIP13/CCNB1/BLM/ZWINT/CDT1/CENPF/CLSPN/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/BUB1/DTL/GTSE1/BUB1B
GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION 270 0.4288050 1.650773 0.0000376 0.0010332 0.0008337 3215 PLA2G3/EBI3/CD70/TNFSF9/ITGAM/CCL5/CLCF1/LBP/IGF2/FOXP3/IL1RL1/IL1B/VCAM1/THBS1/IL23A/CD177/NR4A3/FYN/IL4I1/ADAM8/MYD88/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/TNFRSF13C/TNF/TICAM1/CARD11/LGALS1/CD55/VNN1/STXBP1/CD47/CD274/LGALS9/PLPP6/MEF2C/TLR4/PTAFR/TNIP2/CLEC7A/HLA-G/JUND/PRKCQ/HLA-F/CDKN1A/DUSP10/CD276/STX4/CD46/LYN/NFKBIZ/IRS2/IL15RA/BLOC1S3/HLA-DOB/TNFSF14/NFKBID/SELP/GAB2/NOD2/PELI1/SOX4/BCL10/CD40/IL7R/HLA-E/MAP3K8/PTPN22/TOX/ANXA1/F2RL1/SHLD1/THY1/PNP/SYK/SHLD2/MMP14/RIPK2/SLC7A1/SRC/MALT1/IL4R/TYK2/TFRC/CD86/IL15/NECTIN2/NCK1/CTSC/IL18/SHLD3/FADD/ZBTB7B/PLA2G4A/TIRAP/HLA-A/BTN2A2/PTPN11/TGFBR2/SIRPA/HLA-DMA/SH3KBP1/ACTA2/CAV1/RUNX3
GOBP_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION 23 -0.7538232 -2.077560 0.0000385 0.0010507 0.0008478 537 MTBP/HASPIN/CDT1/TTK/KNL1/CDK1/NDC80
GOBP_CHROMOSOME_CONDENSATION 40 -0.6714381 -2.074125 0.0000395 0.0010730 0.0008658 193 GPER1/CDK1/PLK1/CDCA5/H1-5/H1-1/NCAPH/TOP2A/NCAPG
GOBP_NUCLEOSIDE_BISPHOSPHATE_BIOSYNTHETIC_PROCESS 55 0.6291240 1.951512 0.0000405 0.0010895 0.0008791 906 ELOVL6/ACSS2/ACLY/ACSL1/SNCA/HSD17B12/SLC25A1/ACSL4/PANK3/PANK1/ELOVL5/ELOVL7/ACACA
GOBP_T_CELL_ACTIVATION 362 0.4057908 1.606282 0.0000406 0.0010895 0.0008791 3215 FGL2/EBI3/CD70/RSAD2/DLL4/IDO1/TNFSF9/MICA/CCL5/IGF2/FOXP3/IL1B/HSH2D/VCAM1/ZC3H12A/IL23A/CEACAM1/FYN/RELB/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/TNFRSF13C/TNFRSF1B/LAG3/RIPK3/CARD11/LGALS1/CD55/VNN1/FANCA/BATF/CD47/MICB/CD274/LGALS9/PRDM1/FKBP1B/IL18R1/ICAM1/CLEC7A/HLA-G/PRKCQ/DUSP10/LCP1/MSN/DUSP3/CD276/CD46/LYN/NFKBIZ/CADM1/BTN3A1/ARG2/HLA-DOB/TNFSF14/NFKBID/CD151/MAPK8IP1/NOD2/PELI1/SOX4/BCL10/CTPS1/IL7R/HLA-E/MAP3K8/PTPN22/TOX/SRF/ZEB1/ANXA1/PTPN2/F2RL1/ELF4/PRELID1/PDE5A/THY1/PNP/SYK/ADAM17/BCL3/RIPK2/SLC7A1/SRC/MALT1/IL4R/RAB27A/TYK2/CCND3/EGR1/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/WNT4/SOS2/IL18/MYH9/FADD/ZBTB7B/CASP8/RUNX2/PKNOX1/HLA-A/BTN2A2/PTPN11/KIF13B/TGFBR2/SIRPA/HLA-DMA/CAV1/FZD5/RUNX3
GOBP_RESPONSE_TO_TUMOR_NECROSIS_FACTOR 192 0.4651349 1.728842 0.0000409 0.0010910 0.0008803 3661 HYAL1/CCL22/CD70/CCL4/SLC2A4/CCL20/CXCL8/HYAL3/CCL5/KLF2/VCAM1/THBS1/ZC3H12A/PTGS2/BIRC3/EDN1/TNFSF13B/GBP2/ANKRD1/CX3CL1/TNFRSF13C/TNF/CXCL16/TNFRSF1B/STAT1/NFKBIA/GBP1/PCK2/UBD/TNFAIP3/ASS1/GCH1/ADAM9/CYP1B1/TRAF1/AKAP12/ST18/COL1A1/CCL17/SPHK1/KRT18/CD40/RFFL/MAPK3/PTPN2/F2RL1/SYK/ADAM17/ILK/TRAF2/TMSB4X/GPS2/FAS/ZFP36/CLDN1/GBP3/HYAL2/TRADD/NFKB1/DAB2IP/PID1/MAP3K5/NKIRAS2/CASP8/SMPD1/TRAF5/NUB1/GSDME/TNFRSF1A/COMMD7/EXT1/HAS2/ARHGEF2/RELA/SHARPIN/TNFRSF25/AIM2/IL18BP/TRAF3IP2
GOBP_TRIGLYCERIDE_METABOLIC_PROCESS 69 0.6051059 1.966560 0.0000436 0.0011400 0.0009198 1290 PNPLA3/APOC1/PCSK9/INSIG1/LIPC/LIPG/LPIN1/LDLR/ACSL1/SCARB1/MFSD2A/PCK2/LIPH/APOBR/LIPE/GPAT3
GOBP_PROTEIN_LOCALIZATION_TO_CHROMOSOME 88 -0.5426552 -1.950349 0.0000431 0.0011400 0.0009198 2301 RUVBL2/FAM47E/SLF1/WRAP53/MTBP/MRNIP/LRWD1/IFFO1/EZH2/HASPIN/CDT1/TTK/KNL1/CDK1/NDC80/PLK1/ESCO2/CDCA5/H1-5
GOBP_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS 130 0.5070176 1.795190 0.0000437 0.0011400 0.0009198 1727 PLA2G3/APOC1/DHCR7/INSIG1/FGFR4/LPIN1/MLXIPL/STARD4/LDLR/TRIB3/IL1B/PTGS2/CEACAM1/SCARB1/ELOVL5/MFSD2A/IL1A/TNF/BMP6/ACADL/IDH1/FGF1/BMP2/PDGFB/CCN1/CHP1/GFI1/LPCAT1/SPHK1/DAB2
GOBP_SULFUR_COMPOUND_METABOLIC_PROCESS 274 0.4171700 1.605968 0.0000434 0.0011400 0.0009198 1359 MVD/HMGCS1/ELOVL6/ACSS2/HYAL1/ACOT1/ACLY/CLIC3/MVK/ACSL1/GSTT2B/XDH/SNCA/NUDT8/HSD17B12/SLC7A11/SLC25A1/GGT7/ACSL4/CHAC1/CLIC2/ELOVL5/GGT5/ELOVL7/G6PD/OPLAH/MICAL2/ACACA/CHST1/IDH1/MTHFR/TPK1/SQOR/ENPP1/GLO1/CHPF/CBS/PAX8/ELOVL1/ACOT2
GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY 299 0.4231353 1.645987 0.0000456 0.0011819 0.0009537 3181 THEMIS2/RSAD2/OAS3/OASL/TNIP3/OAS1/LAT2/LBP/FOXP3/CMTM3/IRF7/IFIH1/ZC3H12A/CEACAM1/C5AR2/BIRC3/IRAK2/NR4A3/FYN/PLPP4/IFI35/MYD88/TNIP1/TNF/TICAM1/CARD11/NFKBIA/GBP1/RFTN1/IKBKG/CD47/SLC15A3/MICB/LGALS9/LY96/UBASH3A/DDX60/TNFAIP3/TLR2/NMI/MEF2C/TLR4/TNIP2/CLEC7A/HLA-G/KLRD1/PLSCR1/PRKCQ/PTPRJ/IRAK3/DUSP3/CD276/TYRO3/LYN/NFKBIZ/BTN3A1/GFI1/NFKBID/NOD2/PELI1/BCL10/DHX58/CD40/IRAK1/PTPN22/TRIM25/PTPN2/F2RL1/RNF31/THY1/SYK/BCAR1/RIPK2/SRC/MALT1/NPLOC4/PRKCH/GPS2/SMPDL3B/NOD1/LPXN/RBCK1/LACC1/S100A14/NECTIN2/IRF1/MFHAS1/RTN4/DAB2IP/MAPKAPK2/SLC15A4/PLCG1/TIRAP/HLA-A/BTN2A2/BTN3A3/MAPKAPK3/FLOT1/RPS6KA3/CAV1
GOBP_RESPONSE_TO_WOUNDING 433 0.3814135 1.531297 0.0000471 0.0012146 0.0009801 2736 NTRK1/PAX6/SPRR3/NREP/PLAUR/RTN4R/NTRK3/SERPINC1/FGF2/KDR/SLC7A11/EREG/PLAU/THBS1/CEACAM1/SCARB1/TFPI2/PROCR/PEAR1/EDN1/TNFRSF12A/FOXC2/PF4V1/SERPINE1/VWF/SERPINB2/CD34/DGKI/SCARF1/EMILIN2/MAP1B/IL1A/CX3CL1/OCLN/S100A8/TNF/VEGFA/DYSF/HBEGF/STXBP1/JUN/CLDN4/FGF1/ACVRL1/FOXA2/ENTPD2/RAP2B/SAA1/C1QTNF1/TNFAIP3/FKBP1B/PDGFB/TGFB2/TLR4/CCN1/ADIPOR2/VCL/MYL9/CLEC7A/SH2B3/PLSCR1/PRKCQ/CDKN1A/KLF4/FERMT1/INHBA/LCP1/ADTRP/MYC/VKORC1/DUOX2/TYRO3/LYN/PHLDB2/PRKG1/CHMP7/ITGB3/WNT7A/MMP12/GNA12/BLOC1S3/COL1A1/SELP/CD151/PLPP3/ITPK1/CSRP1/RIPOR1/CD40/ANXA8/ISL1/CHMP6/MYL12A/CCN4/CDH3/SRF/ANXA1/F2RL1/KRT6A/SERPINF2/ID3/TFPI/SYK/ADAM17/CD9/TPM1/ITGB6/P2RX4/ILK/HMOX1/DCBLD2/SERPINE2/SLC12A2/FLNA/TGFBR1/SRC/PAFAH2/RHOC/INPP5F/TGFA/RAB27A/MSX2/MAP2K1/F3/NRG1/CNN2/ZFP36/CLDN1/ACTB/NDEL1/C6orf89/WNT4/ACTG1/PPIA/DAG1
GOBP_NON_MEMBRANE_BOUNDED_ORGANELLE_ASSEMBLY 341 -0.3678643 -1.548310 0.0000489 0.0012555 0.0010131 3166 HAUS4/RPS28/CCDC57/CDS1/CEP44/CENPW/CEP76/MAPRE3/RBM14/RPL3/CEP135/GOLGA8B/HAUS1/PIBF1/CNOT6L/RPS23/CEP295/RPL11/NOP53/HSPA1A/RPSA/GOLGA8A/STIL/RPL6/DEUP1/HAUS5/CEP97/RPS14/PUM2/TOGARAM2/CCDC61/RPL5/CENPC/C9orf72/CENPH/ABRAXAS1/CEP120/SASS6/CCP110/CAPN3/MAPK15/BRCA1/CENPJ/STARD9/WDR62/CEP152/CETN2/MAP10/MDM1/KLHL41/RACGAP1/ADPRHL1/FBXO5/MYLK3/NEB/MCIDAS/CCDC78/KIF11/AURKA/CSRP2/HCK/FLNC/CENPK/TNNT3/KIF23/CENPF/GOLGA8M/CSF2/KIF15/SPAG5/ANLN/NDC80/PLK1/CENPE/NEK2/CCNB2/PLK4/KIF4A/TPX2/DLGAP5/GOLGA8H/CDC20/KIFC1/ASPM/MYBL2
GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION 163 0.4816594 1.760941 0.0000494 0.0012603 0.0010169 2009 PLA2G3/TNFAIP6/MT1G/FASN/LIF/EVI2B/BATF3/BATF2/IRF7/IL23A/CEACAM1/LRRC17/CSF3/IL31RA/RELB/FOS/PRXL2A/CAMK4/TNF/FAM20C/VEGFA/GPR68/JUN/BATF/UBD/LGALS9/FSTL3/TLR2/TLR4/GLO1/ITGB8/INHBA/TFE3/MYC/IL34/CSF1/LYN/TRIB1/PPARGC1B/GAB2/IFI16/CTNNBIP1/KLF10/CCN4/SBNO2/PTPN2/F2RL1
GOBP_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS 98 0.5484206 1.864628 0.0000560 0.0014209 0.0011465 980 PLA2G3/APOC1/INSIG1/FGFR4/MLXIPL/STARD4/TRIB3/SNCA/SLC7A11/IL1B/PTGS2/CNR1/CEACAM1/ELOVL5/NR4A3/MFSD2A/BMP6/ACADL/SOX9/BMP2
GOBP_AXONEME_ASSEMBLY 78 -0.5585574 -1.960956 0.0000578 0.0014599 0.0011780 3340 DNAAF5/DNAI3/DRC1/SPAG6/DNAAF10/CFAP100/ZMYND10/ODAD4/LRGUK/CFAP91/ARMC2/FOXJ1/DNAAF11/DNAAF3/CFAP47/CFAP46/HOATZ/TTLL3/BBS2/CFAP69/DNAAF4/DNAL1/CFAP58/ODAD1/CCDC40/DNAJB13/RSPH9/DRC7/ODAD3/SPAG17/CFAP73/CFAP157/CC2D2A/DAW1/TTC12/DNAI1/RSPH1/DNAH7/IQCG/SPEF2/CCDC39/SPAG16/CCDC65/HYDIN/CFAP206/TEKT2/LRRC49/DNAI4/CFAP65/DNAI2/CFAP74/CFAP44/MNS1/DNAAF8/DNAH1/DNAH5/CFAP43/ODAD2/DNAAF6/RP1/DNAAF1/DNAH2/MEIG1
GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS 209 0.4440940 1.671355 0.0000595 0.0014941 0.0012056 3323 EBI3/CD70/RSAD2/BACH2/MICA/CLCF1/FOXP3/IL1RL1/IL1B/IRF7/ZC3H12A/IL23A/CEACAM1/NFKB2/RELB/IL4I1/ARID5A/MYD88/TNFSF13B/TNF/TNFRSF1B/RIPK3/CD55/RFTN1/BATF/UNC13D/CD274/C4BPA/TNFAIP3/IL18R1/MEF2C/TLR4/ICAM1/CLEC7A/HLA-G/KLRD1/C1S/PRKCQ/HLA-F/PVR/CD46/NFKBIZ/CADM1/HLA-DOB/NFKBID/NOD2/BCL10/CD40/IL7R/HLA-E/ANXA1/SHLD1/TRPM4/C8B/ADAM17/SHLD2/RNF168/HLA-B/BCL3/RIPK2/TRAF2/MALT1/IL4R/RAB27A/AHR/TFRC/NECTIN2/CTSC/IL1R1/SWAP70/C2/IL18/C3/SHLD3/FADD/SLC15A4/ZBTB7B/PLA2G4A/HLA-A/HLA-DMA/BTN3A3/FZD5/EMP2/MAD2L2/BTN3A2
GOBP_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS 63 0.5962516 1.909282 0.0000603 0.0015046 0.0012141 2425 IDO1/SLC7A11/CCL5/HSH2D/IRF7/TSC22D3/ADAM8/RIPK3/CD274/LGALS9/MEF2C/PRKCQ/SELENOS/CDKN2A/LYN/IRS2/ARG2/NOD2/BCL10/IL7R/ANXA1/PRELID1/ADAM17/PIP/ST3GAL1
GOBP_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEGREGATION 42 -0.6599689 -2.068812 0.0000624 0.0015504 0.0012510 1115 FBXO5/MAD1L1/TRIP13/CCNB1/ZWINT/PTTG1/CDT1/CENPF/TTK/MAD2L1/NDC80/PLK1/BUB1/BUB1B
GOBP_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS 340 0.3959589 1.562439 0.0000691 0.0017071 0.0013774 3249 MVD/HMGCS1/ELOVL6/ACSS2/HMGCR/ALDOB/ACOT1/ACLY/SLC2A6/MLXIPL/ALDOC/HKDC1/MVK/ACSL1/XDH/SNCA/NUDT8/HSD17B12/SLC25A1/ACSL4/PANK3/NT5E/PANK1/PDE4C/NUDT10/ELOVL5/NUDT11/ADCY10/ELOVL7/CARD11/NOS2/ACACA/ENPP1/ELOVL1/ACOT2/MYC/ADCY4/ADCY5/ACOT9/ANTKMT/GALK1/ENO3/GMPR/PPARGC1A/PTHLH/OGDH/GPAT4/ACOT7/DDIT4/HACD2/PDE5A/PNP/ACSL5/PFKFB2/FAR2/PDE9A/ENTPD5/ELOVL4/NUDT16/BPGM/GUCY1A2/PMVK/TMSB4X/PDE8A/DGAT1/LACC1/EPHA2/TJP2/DIP2A/TIGAR/FOXK2/NT5C2/GDA/SULT1B1/PRXL2C/PID1/PDHB/ADPGK/HK2/FLCN/PFKP/GUK1/HACD1/VCP/DLAT/FITM2/FAR1/ALDOA
GOBP_GLYCEROLIPID_METABOLIC_PROCESS 322 0.4000542 1.572344 0.0000697 0.0017132 0.0013824 1340 PLA2G3/PNPLA3/APOC1/PCSK9/INSIG1/LIPC/LIPG/LPIN1/LDLR/ACSL1/PLA2G4C/FGF2/LCAT/GPCPD1/SCARB1/SOCS2/PIP4P1/ABHD4/MFSD2A/DGKI/GALR2/PCYT2/SOCS1/SELENOI/TMEM86B/ENPP6/PCK2/SOCS3/LIPH/APOBR/MTMR11/PI4K2A/PDGFB/PISD/LIPE/GDPD3/PLSCR1/GPAT3/PLAAT1/PIGW/PGP
GOBP_REGULATION_OF_CHEMOTAXIS 161 0.4726228 1.718628 0.0000728 0.0017807 0.0014368 2694 S100A7/TNFAIP6/CXCL10/CCL4/SLIT2/NTRK3/CXCL8/FGF2/KDR/CCL5/LBP/SEMA3B/CCN3/THBS1/IL23A/C5AR2/SEMA3D/EDN1/SERPINE1/CXCL17/SEMA7A/STX3/VEGFA/FGF1/ARTN/LGALS9/PDGFB/PTPRO/GREM1/PLXNA3/OXSR1/RARRES2/DUSP3/MET/IL34/CSF1/STX4/LYN/TNFSF14/LGMN/SLC8B1/NOD2/DUSP1/SCG2/MAPK3/PTPN2/F2RL1/MOSPD2/TPBG/ADAM17/P2RX4/USP14/PLXNA4/DAPK2/TMSB4X/SEMA3A/ROBO2/F3/SEMA3C/S100A14/SWAP70
GOBP_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE 169 0.4691835 1.722894 0.0000738 0.0017943 0.0014478 2419 TNFAIP6/FGL2/ISG15/LDLR/MVK/OAS3/MICA/OAS1/FOXP3/NT5E/NLRC5/CCN3/CEACAM1/FYN/USP18/CXCL17/CX3CL1/TNFRSF1B/SOCS3/MICB/LGALS9/SAA1/SERPINB4/TNFAIP3/SERPINB9/NMI/TRIM21/PARP14/HLA-G/KLRD1/HLA-F/KLF4/DUSP10/RHBDF2/IRAK3/SELENOS/TYRO3/LYN/CD200/MMP12/ARG2/STAT2/NOD2/FNDC4/IFI16/C1QTNF3/DHX58/HLA-E/ISL1/TRAFD1/ADAR/PTPN2/METRNL/SYK/FURIN/MAPK7/HLA-B/SRC/NPLOC4/GPS2/SMPDL3B
GOBP_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS 87 0.5539909 1.853841 0.0000754 0.0018252 0.0014727 2105 S100A7/TNFAIP6/CXCL10/CCL4/SLIT2/CXCL8/CCL5/LBP/CCN3/THBS1/IL23A/C5AR2/EDN1/SERPINE1/CXCL17/VEGFA/LGALS9/GREM1/OXSR1/RARRES2/IL34/CSF1/LYN/TNFSF14/LGMN/SLC8B1/NOD2/DUSP1/MAPK3/F2RL1/MOSPD2/ADAM17
GOBP_KERATINOCYTE_DIFFERENTIATION 101 0.5330497 1.819764 0.0000787 0.0018948 0.0015289 1457 SPRR2E/SPRR2F/SPRR2A/S100A7/SPRR1A/PAX6/SPRR3/SPRR2D/EREG/IVL/CLIC4/CYP26B1/SFN/IL1A/SCEL/ERRFI1/ZBED2/KRT17/TRIM16/SPRR1B/ADAM9/OPN3
GOBP_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS 226 0.4464594 1.696410 0.0000824 0.0019723 0.0015914 3604 PNPLA3/PCSK9/INSIG1/GRB14/LPIN1/SLC29A2/SLC2A4/TRIB3/NR4A1/IGF2/IL1B/HDAC9/CEACAM1/SOCS2/NAMPT/NR4A3/EDN1/FOXC2/GDF15/MAP1B/CPEB2/RAB8B/SOCS1/STAT1/PCK2/SOCS3/ERRFI1/ASS1/ENPP1/PRKCQ/GRB10/RARRES2/SELENOS/MYC/CYP1B1/LYN/IRS2/KL/MYO1C/MARS1/PTPN2/TBC1D4/BCAR3/GOT1/SLC27A4/PIP4K2A/GPT/BCAR1/SRC/STAT5A/LPIN2/CCND3/YWHAG/SLC9A1/PIP4K2C/NDEL1/NCK1/NFKB1/PIK3C2A/CAV2/SLC25A33/PID1/ZBTB7B/CDC6/PTPN11/RAB12/SLC39A14/ZDHHC7/CAV1/MYO5A/GJB2/RANGAP1/GRB7/GNAI2/PIP4K2B/EPRS1/CFLAR/SP1/RELA/IRS1/CAPN10/SHC1/CRK
GOBP_RESPONSE_TO_INTERFERON_ALPHA 19 0.7943011 1.983454 0.0000860 0.0020487 0.0016531 2232 IFIT2/MX2/IFITM1/IFIT3/BST2/IFITM3/LAMP3/EIF2AK2/ADAR/IFITM2
GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION 223 0.4439309 1.683512 0.0000913 0.0021628 0.0017452 3036 MUC21/FGL2/IDO1/FOXP3/RND1/THBS1/ZC3H12A/CEACAM1/IL4I1/SERPINE1/IL1RN/CX3CL1/SOCS1/SPRY4/BMP6/VEGFA/LAG3/GBP1/ACVRL1/CD274/BMP2/LGALS9/C1QTNF1/FXYD5/PTPRO/MELTF/ASS1/SH2B3/HLA-G/KLF4/PLXNA3/PODXL/ADTRP/DUSP3/CYP1B1/CDKN2A/PHLDB2/PRKG1/MMP12/ARG2/COL1A1/ACER2/PELI1/EFNA5/PTPN22/DUSP1/ANXA1/PTPN2/PLXNA1/DLC1/PDE5A/ABCA12/CD9/SPOCK1/TGFBI/MMP14/MAPK7/PLXNA4/MAP4K4/SERPINE2/SRC/IL4R/LPXN/TACSTD2/CD86/ARHGDIA/SWAP70/CEBPB/IRF1/MUC1/EPCAM/CDH1/ZBTB7B/MYADM/BTN2A2/PTPN11
GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION 354 0.3945957 1.564132 0.0000965 0.0022763 0.0018368 3244 HYAL1/EBI3/CD70/PLAUR/TNFSF9/LIF/KDR/HSD17B12/CCL5/IGF2/FOXP3/IL1B/VCAM1/IL23A/OLFM4/NR4A3/FYN/FOXC2/IL4I1/ADAM8/CD83/TNFSF13B/EMILIN2/IL1A/CX3CL1/SOCS1/IL1RL2/TNFRSF13C/TNF/CEACAM6/STX3/VEGFA/CARD11/LGALS1/CD55/VNN1/UNC13D/CD47/CD274/FOXA2/LGALS9/SAA1/PIEZO1/NEDD9/FSTL3/FUT3/CYTH3/PDGFB/TGFB2/PTAFR/CCN1/HLA-G/RRAS/PRKCQ/PTPRJ/TRIOBP/FERMT1/PODXL/DUSP10/VIT/ADAM9/TFE3/CD276/CSF1/RAC3/STX4/CD46/LYN/FRMD5/NFKBIZ/HLA-DOB/TNFSF14/NFKBID/SELP/NOD2/DAB2/ETS1/SOX4/PLPP3/BCL10/IL7R/HLA-E/IRAK1/MAP3K8/PTPN22/S100A10/ANXA1/SERPINF2/TJP1/ITGAV/THY1/PNP/SYK/TPM1/ILK/COL16A1/MAP4K4/RIPK2/SLC7A1/FLNA/ITGA3/SRC/MALT1/RHOD/IL4R/TYK2/ARPC2/TFRC/RSU1/CD86/IL15/NCK1/WNT4/DAG1/IL18/DOCK5/P4HB/FADD/ZBTB7B/MYADM/JUP/ITGA5/HLA-A/BTN2A2/PTPN11/TGFBR2/JAK1/SIRPA/FLCN/GFUS/ADGRG1/HLA-DMA/PDPN/FLOT1/CAV1/CHST2/RUNX3/TESK1
GOBP_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS 139 0.4919110 1.755936 0.0000975 0.0022883 0.0018464 2408 ZBP1/ISG15/SLIT2/OAS3/OAS1/IL1R2/CCL5/NLRC5/IRF7/IFIH1/IRAK2/EDN1/USP18/IL1RN/SOCS1/PARP9/IKBKE/TNFAIP3/TLR2/TLR4/PARP14/SH2B3/KLF4/IRAK3/CSF1/MMP12/GFI1/PALM3/STAT2/SPHK1/RFFL/IRAK1/USP27X/ADAR/PTPN2/F2RL1/PXDN/SYK/ADAM17/MAPK7/RIPK2/TRAF2/GPS2
GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING 175 0.4628158 1.703306 0.0000999 0.0023319 0.0018816 3681 S100A12/IL1B/BST2/BIRC3/FYN/MYD88/IL1A/CX3CL1/CASP10/TNF/TICAM1/CARD11/LGALS1/IFIT5/SLC20A1/IKBKG/UBD/LGALS9/IKBKE/TRIM21/TRIM5/TLR4/TNIP2/CLEC7A/TRIM14/SHISA5/SECTM1/NOD2/PELI1/BCL10/CD40/IRAK1/LURAP1L/TRIM25/F2RL1/RNF31/TAB3/CTH/HMOX1/RIPK2/TRIM22/TRAF2/GOLT1B/FLNA/MALT1/RHOC/NOD1/RBCK1/TMEM106A/TFRC/MAP3K3/TRADD/PLEKHG5/ECM1/TNFRSF10B/FADD/CASP8/TIRAP/TRAF5/MUL1/TRIM27/PLK2/TNFRSF1A/CFLAR/RELA/SHARPIN/S100A4/SLC44A2/TRAF3IP2/LITAF/RHOA
GOBP_DNA_REPLICATION_INDEPENDENT_CHROMATIN_ORGANIZATION 32 -0.6950848 -2.048955 0.0001041 0.0024065 0.0019418 3093 H4C2/CENPW/H4C6/NASP/H3-3A/H4C12/MIS18A/H4C4/H4C13/CENPP/H4C1/OIP5/H4C9/ASF1B/HJURP
GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING 255 0.4300472 1.651154 0.0001041 0.0024065 0.0019418 3681 S100A12/TNIP3/IL1B/BST2/ZC3H12A/BIRC3/IRAK2/EDN1/FYN/RELB/MYD88/IL1A/CX3CL1/CASP10/TNIP1/TNF/RIPK3/TICAM1/STAT1/CARD11/LGALS1/NFKBIA/IFIT5/SLC20A1/IKBKG/UBD/LGALS9/IKBKE/TNFAIP3/TLR2/TRIM21/TRIM5/TLR4/TNIP2/CLEC7A/TRIM14/TLE1/TRAF1/OPTN/SHISA5/SECTM1/NOD2/PELI1/BCL10/CD40/IRAK1/LURAP1L/TRIM25/F2RL1/RNF31/TAB3/SQSTM1/CTH/HMOX1/BCL3/RIPK2/TRIM22/TRAF2/GOLT1B/FLNA/MALT1/RHOC/NOD1/RBCK1/TMEM106A/TFRC/MAP3K3/TRADD/NFKBIB/PLEKHG5/ECM1/DAB2IP/TNFRSF10B/FADD/CARD19/NKIRAS2/CASP8/TIRAP/TRAF5/SIRPA/DDRGK1/MUL1/TRIM27/PLK2/TNFRSF1A/CFLAR/RELA/SHARPIN/S100A4/SLC44A2/TRAF3IP2/LITAF/RHOA
GOBP_PYRIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS 33 0.7061658 1.981321 0.0001107 0.0025458 0.0020542 2094 QPRT/IDO1/IDO2/ALPL/KYNU/SLC5A8/KMO/PSAT1/NAMPT/PARP9/NUDT17/HAAO/PDXK/NADK/PNP
GOBP_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS 28 0.7379423 2.012460 0.0001147 0.0026255 0.0021185 2327 APOC1/LPIN1/LDLR/SCARB1/MFSD2A/IDH1/PDGFB/CHP1/LPCAT1/ABCA3/CAPN2
GOBP_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE 52 -0.5980795 -1.929091 0.0001169 0.0026497 0.0021380 2420 ANKRD31/C14orf39/MRE11/NCAPD3/NDC1/MSH5/PSMC3IP/SMC4/RNF212/SMC2/SYCP2/BRIP1/CCNE1/TRIP13/MAJIN/RAD51/SGO2/CCNE2/BUB1/DMC1/NCAPH/SGO1/BUB1B
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE 267 -0.3805732 -1.554988 0.0001169 0.0026497 0.0021380 2196 CITED2/SLF1/SOX15/SMPD3/RRM1/MEIS2/PRKCE/CEP120/CKS2/SASS6/CIT/XRCC3/MAPK15/CENPJ/MTBP/DRD2/CDC7/CDC14A/TGM1/MAP10/STOX1/RACGAP1/FBXO5/EZH2/MIR590/ANAPC4/AURKA/MAD1L1/CCNB1/ATAD5/NANOGP8/CDC25C/CDC25A/PSRC1/KIF23/CDT1/RAD51AP1/ESPL1/E2F7/KIF14/KIF20B/FAM83D/MAD2L1/SPAG5/CDK1/SMOC2/NDC80/PLK4/CDCA5/DLGAP5/IGF1/RRM2/DTL/UBE2C
GOBP_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION 219 -0.4031903 -1.617718 0.0001188 0.0026785 0.0021613 1693 XRCC3/JADE1/BRCA1/MRNIP/EME1/GPNMB/FBXO5/STK33/GJC2/EZH2/BRIP1/ORC1/MAD1L1/E2F1/TRIP13/CCNB1/BLM/DNA2/ZWINT/CDT1/CENPF/CLSPN/E2F7/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/BUB1/CDC45/DTL/GTSE1/BUB1B
GOBP_SERTOLI_CELL_DIFFERENTIATION 13 0.8543487 1.967525 0.0001263 0.0028303 0.0022837 884 NTRK1/SCX/IL1A/SOX9
GOBP_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY 222 0.4464077 1.693379 0.0001267 0.0028303 0.0022837 3521 NTRK1/S100A12/LPAR5/IL1B/RELN/LRP8/IRAK2/CSF3/EDN1/PPP2R5B/ADAM8/MYD88/ANXA3/CX3CL1/S100A8/TNF/TRIM31/VEGFA/RIPK3/TICAM1/CARD11/IKBKG/BMP2/LGALS9/IKBKE/TLR2/TRIM21/DDIT3/RTKN2/IL18R1/TRIM5/TLR4/CLEC7A/TRIM14/PRKCQ/GREM1/S100A9/EIF2AK2/DVL2/IRAK3/PSMA6/TRAF1/CD200/PPARGC1B/NOD2/SPHK1/PLPP3/PPARGC1A/BCL10/CD40/IRAK1/SLCO3A1/SRF/TRIM25/RNF31/CEBPG/CTH/RIPK2/TRIM22/TRAF2/MALT1/PRKCH/NOD1/FOSL1/RBCK1/TFRC/TRADD/RPS6KA4/PPIA/IL18/SAV1/JUP/TIRAP/TRAF5/DDRGK1/FLOT1/CAV1/MAP3K13/ARHGEF5/TRIM27/ARHGEF2/CFLAR/RELA/ZC4H2/CRTC3/ADCY1
GOBP_REGULATION_OF_HEMOPOIESIS 281 0.4097894 1.579660 0.0001288 0.0028633 0.0023103 2975 PLA2G3/TNFAIP6/FGL2/ISG15/TCIM/TNFSF9/LIF/EVI2B/FOXP3/IRF7/ZC3H12A/IL23A/CEACAM1/LRRC17/CSF3/FOS/PRXL2A/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/SOCS1/IL1RL2/TNF/LAG3/STAT1/CARD11/LGALS1/NFKBIA/GPR68/MAPK11/VNN1/FANCA/LGALS9/FSTL3/PRDM1/MEF2C/TLR4/HLA-G/INHBA/DUSP10/TFE3/MYC/IL34/CSF1/CD46/LYN/NFKBIZ/TRIB1/PPARGC1B/IL15RA/NFKBID/ETS1/SOX4/CTNNBIP1/TMEM176A/IL7R/KLF10/TOX/ZEB1/ANXA1/PTPN2/PRELID1/PNP/SYK/MMP14/TMEM176B/HLA-B/RIPK2/MALT1/IL4R/ZFP36/CD86/IL15/ZBTB46/CEBPB/IRF1/SOS2/IL18/FAM210B/FADD/KLF13/ZBTB7B/CASP8
GOBP_POSITIVE_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION 44 0.6513918 1.928796 0.0001312 0.0029039 0.0023431 2105 S100A7/CXCL10/CCL4/CCL20/CCL5/SERPINE1/ADAM8/CXCL17/TNF/CD47/LGALS9/OXSR1/TNFSF14/LGMN/MOSPD2/ADAM17
GOBP_NEGATIVE_REGULATION_OF_CELL_CYCLE 328 -0.3607713 -1.505696 0.0001382 0.0030436 0.0024559 1693 XRCC3/JADE1/BRCA1/MTBP/MRNIP/GMNN/MYOCD/EME1/GMNC/GPNMB/MDM1/FBXO5/STK33/NUDT6/HEXIM2/BTG4/GJC2/BMP7/MCIDAS/EZH2/BRIP1/CCNF/ORC1/GPER1/MAD1L1/E2F1/TRIP13/CCNB1/BLM/GAS1/DNA2/CDKN2C/ZWINT/PTTG1/CDT1/CENPF/CLSPN/ESPL1/E2F7/FBXO43/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/NEK2/BUB1/CDC45/DTL/GTSE1/BUB1B
GOBP_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION 104 0.5358419 1.842891 0.0001430 0.0031345 0.0025292 3006 FGFBP1/DLL4/SLIT2/NR4A1/FGF2/MIR200A/KDR/HDAC9/THBS1/PTGS2/SCARB1/FOXC2/TNF/VEGFA/ACVRL1/PDGFB/MEF2C/GREM1/KLF4/ADTRP/CSNK2B/GADD45A/ETS1/AKT3/CD40/SRF/ANXA1/CARD10/ADAM17/HDAC7/P2RX4/EPHB4/HMOX1/TMSB4X/STAT5A/EPHA2/MAP3K3/MAP2K3/PIK3C2A/MYH9/ID1/SRPX2/JUP/PLCG1
GOBP_POSITIVE_REGULATION_OF_MAPK_CASCADE 359 0.3874059 1.536393 0.0001456 0.0031772 0.0025636 2541 NTRK1/S100A7/ADRA1A/FGFR4/CCL22/CCL4/DOK6/CCL20/S100A12/NTRK3/FGF2/NCF1/XDH/LIF/KDR/MAPK8IP2/CCL5/IGF2/IL1B/KLB/THBS1/ZC3H12A/CAVIN3/NOX1/C5AR2/EDN1/DKK1/GDF15/ADAM8/MYD88/CXCL17/SEMA7A/IL1A/CX3CL1/TNF/VEGFA/JUN/GRM1/FGF1/BMP2/LGALS9/FGD2/C1QTNF1/PDGFB/TGFB2/ADRB2/TRIM5/TLR4/ICAM1/CLEC7A/PTPRJ/IL11/ADAM9/EIF2AK2/DVL2/IL34/ABCA7/EGF/TRAF1/AKAP12/FLT1/WNT7A/KL/DOK4/SHC2/GADD45A/MAPK8IP1/BMPER/CCL17/NOD2/SPHK1/CD40/IRAK1/PTPN22/MST1R/PDGFC/GPR37L1/MAPK3/F2RL1/SERPINF2/TPBG/MYDGF/PDE5A/SYK/NTRK2/BCAR3/SPAG9/ERP29/MAP3K10/GAREM1/RIPK2/TRAF2/TGFBR1/SRC/SEMA3A/NOD1/TGFA/TMEM106A/MAP2K1/PDE8A/NRG1
GOBP_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY 464 0.3689653 1.490456 0.0001484 0.0032238 0.0026012 3851 NTRK1/ADRA1A/RGS7/CCL22/CCL4/CCL20/RGS16/RTN4R/NTRK3/FGF2/BBC3/XDH/SNCA/ADPRH/CCL5/PMAIP1/FYN/NLRP2/CX3CL1/CASP10/PML/RASGRP3/S100A8/TNF/VEGFA/RIPK3/TBC1D3D/PSME4/CLDN4/ARHGAP11B/BMP2/LGALS9/NEDD9/EIF2AK3/MEF2C/PTAFR/SNX9/DOCK10/ADAP2/CCN1/CLEC7A/S100A9/TIAM2/DVL2/GNA15/MYC/LYN/ASAP3/ST18/CD200/FLT1/GNA12/PPARGC1B/DDX11/NGEF/LPAR2/PCOLCE2/ACER2/LGMN/CCL17/IFI16/AKIRIN2/BOK/BCL10/PRSS22/CD40/GMIP/BID/RHOG/RGS10/S100A10/F2RL1/ARHGAP27/DLC1/PRELID1/THY1/SYK/TBC1D4/BCAR3/NDUFA13/RAP1GAP/SLC27A4/DOCK6/TNFSF15/MAP4K4/CASP5/RIPK2/NLRP1/MALT1/RHOC/NOD1/FAS/PLAA/ARF4/ADAP1/SYDE2/F3/MAPRE2/BAK1/RSU1/CD86/RAPGEF3/SYDE1/EPHA2/NDEL1/TBC1D25/TBC1D10A/C6orf89/ASAP2/WNT4/SOS2/CAV2/RPS27L/RAP1GAP2/MAP3K5/FADD/ITGA6/CASP8/PSME2/FLCN/DDRGK1/GRHL3/MUL1/VCP/CAV1/RANGAP1/ARHGEF5/TBC1D22B/ABL2/ABHD5/TBC1D10B/ARHGAP29/TBC1D17/CFLAR/BCL2L13/TBC1D1/BIN1/PDGFRA/TGM2/PICALM/CRK/HRAS/PPP1R15B/AIM2/RGP1/MAPK12/APH1A/RHOA/RGS14/SGSM3/ARHGEF10/RAPGEF1/TMEM106B/CHN1/GSK3B/PIP5K1A/SMAD3/MMUT/CORO1C
GOBP_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 153 -0.4414726 -1.710430 0.0001503 0.0032482 0.0026210 1693 XRCC3/JADE1/BRCA1/MRNIP/GPNMB/FBXO5/GJC2/EZH2/ORC1/MAD1L1/TRIP13/CCNB1/BLM/ZWINT/CDT1/CENPF/CLSPN/E2F7/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/BUB1/DTL/GTSE1/BUB1B
GOBP_ACUTE_INFLAMMATORY_RESPONSE 68 0.5748697 1.865659 0.0001560 0.0033561 0.0027080 2818 LBP/IL1B/SERPINA3/VCAM1/HP/PTGS2/CNR1/IL31RA/ADAM8/IL1A/S100A8/TNF/VNN1/SAA1/OSMR/APOL2/PTGES/ASS1/PLSCR1/SAA2/SELENOS/C2CD4A/KL/CTNNBIP1/HLA-E/SERPINF2/TREM1/F3/TFRC/CEBPB/RHBDD3/C3
GOBP_COENZYME_A_METABOLIC_PROCESS 18 0.7885310 1.952658 0.0001571 0.0033650 0.0027152 410 HMGCR/ACLY/NUDT8/PANK3/PANK1
GOBP_THIOESTER_BIOSYNTHETIC_PROCESS 40 0.6609781 1.922589 0.0001583 0.0033747 0.0027230 906 ELOVL6/ACSS2/ACLY/ACSL1/SNCA/HSD17B12/SLC25A1/ACSL4/ELOVL5/ELOVL7/ACACA
GOBP_REGULATION_OF_SECRETION 429 0.3802824 1.524832 0.0001603 0.0034013 0.0027445 2252 PLA2G3/ACHE/CYP51A1/HMGCR/ADRA1A/RSAD2/SYT2/TTN/HYAL3/LIF/SYT1/ITGAM/SNCA/CCL5/ACSL4/OAS2/IL1B/KMO/CCN3/CHRNB4/SYT17/CNR1/CEACAM1/CD177/EDN1/AACS/ADAM8/ANKRD1/IL1A/RAB8B/S100A8/TNF/BMP6/TNFRSF1B/NOS2/GPR68/STXBP1/ADGRE2/SGK1/PCK2/UNC13D/FOXA2/BMP2/LGALS9/SAA1/C1QTNF1/FKBP1B/TLR2/KLF7/TGFB2/PTGES/MEF2C/TLR4/PTAFR/CBARP/LRRC8A/HLA-F/IL11/INHBA/PAX8/RHBDF2/ADAM9/GPR27/ADTRP/ANO1/EGF/STX4/ATP13A2/LYN/ADCY5/RAB11FIP1/TPCN2/CD200/WNT7A/LLGL2/IRS2/GAB2/SLC8B1/DAB2/C1QTNF3/SOX4/CFTR/MICAL1/EFNA5/ZBED6/ISL1/RAB27B/CHMP6/FAM3D/ENSA/GABBR1/ANXA1/F2RL1/GLUD1/DNAJC1/GIPC1/TRPM4/HAP1/TRPV6/ABCA12/SYK/PFKFB2/STX1A/RAB11FIP5/P2RX4/RALA/ERP29/DOC2B/HMOX1
GOBP_ACETYL_COA_METABOLIC_PROCESS 29 0.7123267 1.962284 0.0001671 0.0035145 0.0028358 288 MVD/HMGCS1/ACSS2/ACLY/MVK/NUDT8
GOBP_ACUTE_PHASE_RESPONSE 29 0.7122948 1.962196 0.0001671 0.0035145 0.0028358 1334 LBP/IL1B/SERPINA3/HP/PTGS2/CNR1/IL1A/TNF/SAA1/APOL2/PTGES/ASS1/PLSCR1/SAA2
GOBP_CELLULAR_KETONE_METABOLIC_PROCESS 160 0.4705810 1.709587 0.0001689 0.0035372 0.0028541 980 PLA2G3/APOC1/INSIG1/FGFR4/MLXIPL/STARD4/IDO1/TRIB3/IDO2/SNCA/SLC7A11/KYNU/IL1B/KMO/PTGS2/CNR1/CEACAM1/CYP46A1/ELOVL5/NR4A3/MFSD2A/BMP6/ACADL/SOX9/BMP2
GOBP_T_CELL_PROLIFERATION 153 0.4688922 1.692180 0.0001730 0.0036052 0.0029090 3060 EBI3/CD70/IDO1/TNFSF9/CCL5/IGF2/FOXP3/IL1B/VCAM1/IL23A/FYN/IL4I1/TNFSF13B/IL1A/TNFRSF13C/TNFRSF1B/RIPK3/CARD11/CD55/CD274/LGALS9/FKBP1B/HLA-G/PRKCQ/MSN/CD276/CD46/CADM1/BTN3A1/ARG2/TNFSF14/CD151/MAPK8IP1/PELI1/CTPS1/HLA-E/PTPN22/ANXA1/ELF4/PDE5A/PNP/SYK/RIPK2/SLC7A1/MALT1/TYK2/CCND3/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/WNT4/SOS2/IL18/FADD/ZBTB7B/HLA-A/BTN2A2/TGFBR2
GOBP_PHOSPHATIDIC_ACID_METABOLIC_PROCESS 32 0.7033259 1.957194 0.0001758 0.0036482 0.0029437 1854 PLA2G3/PNPLA3/LPIN1/ABHD4/LIPH/GPAT3/LPCAT1/GPAT4
GOBP_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT 123 0.4991942 1.750668 0.0001870 0.0038635 0.0031174 3125 HYAL1/CCR3/CXCL8/FGF2/KDR/IL1B/ADM2/THBS1/ZC3H12A/FOXC2/ANGPTL4/SERPINE1/CD34/EMILIN2/IL1A/ANXA3/RHOB/VEGFA/FGF1/ACVRL1/VASH2/ENG/RRAS/GREM1/KLF4/ITGB8/CYP1B1/FLT1/BMPER/SPHK1/ETS1/AKT3/CD40/ISL1/TJP1/MYDGF/HMOX1/BTG1/LRG1/F3/RAPGEF3/ECM1/C3/HK2/JUP/PLCG1/ITGA5/TGFBR2/JAK1/TWIST1
GOBP_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS 31 0.7064890 1.961555 0.0001902 0.0039119 0.0031565 826 PLA2G3/APOC1/INSIG1/MLXIPL/TRIB3/IL1B/PTGS2/CEACAM1/ELOVL5/ACADL
GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE 191 0.4554215 1.691456 0.0001912 0.0039149 0.0031589 2462 PLA2G3/FGL2/TCIM/ITGAM/LAT2/CLCF1/LBP/FOXP3/ZC3H12A/IL23A/CEACAM1/SH2D1B/CD177/NR4A3/IFI35/RELB/MYD88/ANXA3/TICAM1/DYSF/LGALS1/STXBP1/ADGRE2/BATF/UNC13D/LGALS9/NMI/IL18R1/TLR4/PTAFR/ICAM1/DOCK10/CLEC7A/HLA-F/LCP1/STX4/CD46/LYN/NFKBIZ/NFKBID/GAB2/CD40/SBNO2/ANXA1/F2RL1/SHLD1/SYK/SHLD2/RNF168/HMOX1/BCL3/RIPK2/MALT1/ST3GAL1/IL4R/RAB27A
GOBP_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY 38 0.6744023 1.945690 0.0001926 0.0039272 0.0031688 2005 ZBP1/ISG15/OAS3/OAS1/NLRC5/IRF7/USP18/IKBKE/MMP12/STAT2/USP27X/ADAR/PTPN2
GOBP_ERK1_AND_ERK2_CASCADE 237 0.4279093 1.633412 0.0001954 0.0039658 0.0031999 2119 NTRK1/S100A7/ADRA1A/FGFR4/CCL22/CCL4/CCL20/DUSP5/NTRK3/FGF2/LIF/KDR/CCL5/ROS1/IL1B/CAVIN3/CEACAM1/C5AR2/EDN1/CXCL17/SEMA7A/IL1A/CX3CL1/ATF3/TNIP1/SPRY4/TNF/CHRNA10/SOX9/GBP1/JUN/FGF1/BMP2/LGALS9/ERRFI1/PDGFB/TLR4/ICAM1/CCN1/RRAS/DUSP6/SPRY1/DUSP10/GRB10/DUSP3/MYC/ABCA7/EGF/LYN/AKAP12/ACE2/BMPER/CCL17/NOD2/DAB2/PTPN22/PDGFC/MAPK3/PTPN2/F2RL1/SERPINF2/ITGAV/TPBG/SYK/NTRK2
GOBP_INTRACILIARY_TRANSPORT 36 -0.6814082 -2.059130 0.0001979 0.0039992 0.0032269 3781 BBS12/TUB/ARL3/WDR19/RABL2B/TRAF3IP1/IFT74/DYNC2I1/SSX2IP/DYNLT2B/IFT43/DYNC2LI1/IFT52/IFT122/IFT140/IFT57/IFT27/WDR35/PCM1/IFT88/LCA5/IFT81/RPGR/IFT172/TTC21A/DYNC2H1/TTC21B/LCA5L
GOBP_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS 450 0.3721207 1.501424 0.0002021 0.0040665 0.0032812 3295 PNPLA3/PCSK9/INSIG1/GRB14/LPIN1/EBI3/SLC29A2/SLC2A4/TRIB3/SLIT2/NR4A1/ACSL1/NPC1/IGF2/FOSB/IL1B/NR2E3/HDAC9/CEACAM1/GNG2/SOCS2/NAMPT/NR4A3/EDN1/FOXC2/FOS/GDF15/ARID5A/MAP1B/CPEB2/RAB8B/SOCS1/STAT1/UCN2/PRLR/SGK1/ACACA/PCK2/SOCS3/HDAC6/PMEPA1/ERRFI1/SERPINB9/MEF2C/ASS1/ADIPOR2/ENPP1/PRKCQ/WBP2/INHBA/PAX8/GRB10/RARRES2/ADTRP/SELENOS/MYC/CYP1B1/LYN/CSNK2B/SFR1/IRS2/PPARGC1B/KL/DAB2/MYO1C/MARS1/EFNA5/ISL1/PHEX/DDIT4/ANXA1/PTPN2/TFPI/TBC1D4/BCAR3/GOT1/SLC5A5/SLC27A4/PIP4K2A/GPT/BCAR1/SRC/KDM4C/STAT5A/LPIN2/CCND3/YWHAG/ROBO2/IGFBP7/SLC9A1/ZFP36/AKAP8/PIP4K2C/NDEL1/NCK1/NFKB1/PIK3C2A/CAV2/SLC25A33/PID1/PAQR8/PGRMC2/NEDD4/ZBTB7B/LATS2/NSMF/VPS18/CDC6/PTPN11/RAB12/CACNA1H/DDRGK1/SLC39A14/ZDHHC7/CAV1/MYO5A/GJB2/RANGAP1/GNB1/GRB7/GNAI2
GOBP_CENTROMERIC_SISTER_CHROMATID_COHESION 11 -0.8705264 -2.003857 0.0002074 0.0041566 0.0033539 363 AXIN2/SGO2/BUB1/SGO1/BUB1B
GOBP_ATTACHMENT_OF_MITOTIC_SPINDLE_MICROTUBULES_TO_KINETOCHORE 14 -0.8248562 -2.001125 0.0002170 0.0043289 0.0034930 758 MAD1L1/CDT1/NDC80/CENPE/NUF2/KIF2C
GOBP_REGULATION_OF_T_CELL_ACTIVATION 248 0.4106785 1.570633 0.0002187 0.0043449 0.0035059 3215 FGL2/EBI3/CD70/IDO1/TNFSF9/CCL5/IGF2/FOXP3/IL1B/VCAM1/ZC3H12A/IL23A/CEACAM1/FYN/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/TNFRSF13C/TNFRSF1B/LAG3/RIPK3/CARD11/LGALS1/CD55/VNN1/FANCA/CD47/CD274/LGALS9/PRDM1/HLA-G/PRKCQ/DUSP10/DUSP3/CD276/CD46/LYN/NFKBIZ/ARG2/HLA-DOB/TNFSF14/NFKBID/MAPK8IP1/NOD2/PELI1/SOX4/BCL10/IL7R/HLA-E/MAP3K8/PTPN22/TOX/ZEB1/ANXA1/PTPN2/PRELID1/PDE5A/THY1/PNP/SYK/RIPK2/SLC7A1/SRC/MALT1/IL4R/TYK2/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/SOS2/IL18/FADD/ZBTB7B/HLA-A/BTN2A2/PTPN11/TGFBR2/SIRPA/HLA-DMA/CAV1/RUNX3
GOBP_REGULATION_OF_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE 12 -0.8473021 -1.972223 0.0002261 0.0044354 0.0035789 1174 RACGAP1/CCNB1/SPAG5/NEK2
GOBP_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS 50 0.6346280 1.920333 0.0002249 0.0044354 0.0035789 2252 FGFBP1/DLL4/SLIT2/NR4A1/FGF2/KDR/HDAC9/THBS1/PTGS2/FOXC2/VEGFA/GREM1/KLF4/ADTRP/AKT3/SRF/ANXA1/CARD10/HDAC7/EPHB4/HMOX1
GOBP_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS 67 0.5771196 1.866109 0.0002254 0.0044354 0.0035789 884 PLA2G3/APOC1/INSIG1/MLXIPL/TRIB3/SNCA/IL1B/PTGS2/CNR1/CEACAM1/ELOVL5/NR4A3/MFSD2A/ACADL/SOX9
GOBP_INTERLEUKIN_1_MEDIATED_SIGNALING_PATHWAY 27 0.7181646 1.941007 0.0002310 0.0045122 0.0036408 2718 ZBP1/IL1R2/IL1B/IRAK2/MYD88/IL1RN/IL1RL2/TNIP2/IRAK3/ST18/IRAK1/MAPK3/EGR1/IL1R1/RPS6KA4
GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY 40 0.6501961 1.891227 0.0002330 0.0045335 0.0036580 2437 PLA2G3/CXCL6/ITGAM/CD177/CAMK4/TICAM1/STXBP1/ADGRE2/UNC13D/LGALS9/PTAFR/STX4/LYN/GAB2/HLA-E/F2RL1/SYK/HMOX1/IL4R
GOBP_PROTEIN_LOCALIZATION_TO_CONDENSED_CHROMOSOME 18 -0.7833819 -2.016042 0.0002423 0.0046948 0.0037882 537 MTBP/HASPIN/CDT1/TTK/KNL1/CDK1/NDC80
GOBP_KERATINIZATION 28 0.7236879 1.973587 0.0002707 0.0052220 0.0042136 1326 SPRR2E/SPRR2F/SPRR2A/SPRR1A/SPRR3/SPRR2D/IVL/CYP26B1/SFN/IL1A/KRT17/SPRR1B
GOBP_KINETOCHORE_ORGANIZATION 22 -0.7494002 -2.056496 0.0002776 0.0052894 0.0042679 2062 SMC4/CENPC/CENPH/SMC2/CENPK/CDT1/CENPF/NDC80/CENPE/DLGAP5/NUF2
GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE 138 0.4727582 1.688980 0.0002774 0.0052894 0.0042679 3379 RSAD2/CLCF1/FOXP3/IL1RL1/IL1B/IRF7/ZC3H12A/IL23A/CEACAM1/IL4I1/ARID5A/TNFSF13B/TNF/TNFRSF1B/RIPK3/CD55/CD274/C4BPA/TNFAIP3/IL18R1/MEF2C/CLEC7A/HLA-G/KLRD1/PRKCQ/HLA-F/PVR/DUSP10/CD46/NFKBIZ/NFKBID/NOD2/CD40/IL7R/HLA-E/ANXA1/SHLD1/TRPM4/SHLD2/HLA-B/RIPK2/TRAF2/MALT1/IL4R/AHR/TFRC/NECTIN2/IL1R1/IRF1/IL18/C3/SHLD3/FADD/SLC15A4/ZBTB7B/PLA2G4A/HLA-A/FZD5/TRIM27/ADCY7/MAD2L2/MR1
GOBP_EPIDERMAL_CELL_DIFFERENTIATION 151 0.4603292 1.657375 0.0002756 0.0052894 0.0042679 1457 SPRR2E/SPRR2F/SPRR2A/S100A7/SPRR1A/PAX6/SPRR3/SPRR2D/EREG/MAFF/IVL/CLIC4/CYP26B1/SFN/IL1A/FA2H/OVOL1/SCEL/ERRFI1/ZBED2/KLF7/KRT17/TRIM16/KLF4/SPRR1B/TRIOBP/ADAM9/OPN3
GOBP_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 80 -0.5224518 -1.840351 0.0002789 0.0052927 0.0042707 1590 CENPJ/MTBP/CDC7/STOX1/FBXO5/ANAPC4/CCNB1/CDC25C/CDC25A/CDT1/ESPL1/CDK1/CDCA5/DLGAP5/RRM2/DTL/UBE2C
GOBP_INDOLALKYLAMINE_METABOLIC_PROCESS 10 0.8726233 1.863066 0.0002858 0.0054020 0.0043588 1470 IDO1/IDO2/KYNU/KMO/IL4I1/HAAO
GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION 136 0.4720814 1.677113 0.0002991 0.0056310 0.0045436 3102 HYAL1/FGFBP1/FGF2/MIR200A/KDR/HDAC9/THBS1/ZC3H12A/PTGS2/SCARB1/EDN1/FOXC2/ANXA3/RHOB/VEGFA/HBEGF/SOX9/JUN/FGF1/HDAC6/PDGFB/TGFB2/RRAS/ADAM9/ATOH8/MET/EGF/ITGB3/WNT7A/LGMN/ETS1/PLPP3/AKT3/CD40/ANXA1/ADAM17/HDAC7/P2RX4/HMOX1/MAP4K4/BCAR1/ITGA3/TMSB4X/SRC/STAT5A/MAPRE2/MAP3K3/MAP2K3/PIK3C2A/DOCK5/RTN4/SRPX2/PLCG1/SPARC/TGFBR2/GFUS
GOBP_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS 26 0.7220012 1.927057 0.0003033 0.0056867 0.0045885 1885 QPRT/IDO1/IDO2/KYNU/SLC5A8/KMO/PSAT1/NAMPT/PARP9/HAAO/PDXK/NADK
GOBP_HORMONE_TRANSPORT 203 0.4338852 1.621545 0.0003058 0.0057109 0.0046080 2148 PLA2G3/LIF/CCL5/ACSL4/IL1B/SLCO4A1/CCN3/CNR1/EDN1/AACS/CLTRN/SLCO1B1/IL1RN/RAB8B/TNF/BMP6/NOS2/GPR68/PCK2/FOXA2/C1QTNF1/FKBP1B/KLF7/LRRC8A/IL11/INHBA/PAX8/GPR27/ANO1/STX4/LYN/ADCY5/RAB11FIP1/IRS2/SLC8B1/DAB2/C1QTNF3/SOX4/CFTR/EFNA5/ZBED6/ISL1/CRYM/FAM3D/ENSA/GABBR1/ANXA1/GLUD1/NIBAN2/TRPM4/TRPV6/ABCA12/PFKFB2/STX1A/RAB11FIP5
GOBP_REGULATION_OF_LYMPHOCYTE_MIGRATION 44 0.6367903 1.885560 0.0003210 0.0059712 0.0048181 1714 S100A7/CXCL10/CCL4/CCL20/CCL5/ADAM8/RIPK3/STK10/OXSR1/MSN/ADTRP/CD200/TNFSF14/SLC8B1
GOBP_T_CELL_CYTOKINE_PRODUCTION 26 0.7195550 1.920528 0.0003314 0.0061400 0.0049543 3192 RSAD2/FOXP3/IL1B/ARID5A/TNFRSF1B/CD55/IL18R1/HLA-F/TRPM4/TRAF2/MALT1/IL1R1/IL18/HLA-A/FZD5
GOBP_RESPONSE_TO_EXTRACELLULAR_STIMULUS 367 0.3775645 1.500357 0.0003436 0.0063407 0.0051163 1996 NTRK1/PCSK9/SGIP1/CXCL10/FADS1/LIPG/LDLR/SLC8A1/ACSL1/ALPL/ASCL1/KYNU/VCAM1/KIF26A/ZC3H12A/PTGS2/CNR1/PMAIP1/CDKN2B/FOS/GDF15/STC2/MFSD2A/CYP26B1/MAP1LC3B2/MAP1B/IL1A/DSC2/ATF3/G6PD/TNF/STAT1/SREBF2/UCN2/TPH2/PCK2/FOXA2/MTHFR/FKBP1B/EIF2AK3/DDIT3/ADRB2/ATF4/ASS1/GABARAPL1/CDKN1A/SLC25A25/CBS/EIF2AK2/CYP1B1/LYN/PIM1/KL/WIPI1/COL1A1/NOD2/IFI16/PPARGC1A/MARS1/NOCT/BCL10/RIPOR1/KLF10/SESN2/HTR4/PHEX/UPP1/ENSA/ARSB/SRF/TRIM25/ZEB1/MAPK3
GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION 224 0.4244581 1.613140 0.0003469 0.0063771 0.0051456 3215 EBI3/CD70/PLAUR/TNFSF9/CCL5/IGF2/FOXP3/IL1B/VCAM1/IL23A/NR4A3/FYN/IL4I1/ADAM8/CD83/TNFSF13B/EMILIN2/IL1A/CX3CL1/SOCS1/IL1RL2/TNFRSF13C/TNF/CEACAM6/CARD11/LGALS1/CD55/VNN1/CD47/CD274/FOXA2/LGALS9/PIEZO1/FSTL3/FUT3/PTAFR/HLA-G/PRKCQ/PODXL/DUSP10/CD276/CD46/LYN/NFKBIZ/HLA-DOB/TNFSF14/NFKBID/SELP/NOD2/ETS1/SOX4/PLPP3/BCL10/IL7R/HLA-E/IRAK1/MAP3K8/PTPN22/ANXA1/SERPINF2/TJP1/THY1/PNP/SYK/RIPK2/SLC7A1/SRC/MALT1/IL4R/TYK2/TFRC/CD86/IL15/NCK1/IL18/FADD/ZBTB7B/HLA-A/BTN2A2/PTPN11/TGFBR2/JAK1/SIRPA/HLA-DMA/PDPN/FLOT1/CAV1/CHST2/RUNX3
GOBP_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 69 0.5673061 1.843712 0.0003499 0.0064066 0.0051695 2470 FGL2/MICA/FOXP3/BST2/ZC3H12A/CEACAM1/IL4I1/TNF/CD55/CD47/LGALS9/C4BPA/SERPINB4/SERPINB9/TGFB2/HLA-G/KLRD1/HLA-F/DUSP10/IRAK3/CD46/NOD2/IL7R/HLA-E/ANXA1/HLA-B/HMOX1/IL4R/AHR
GOBP_MYELOID_CELL_DIFFERENTIATION 318 0.3859634 1.511602 0.0003661 0.0066776 0.0053881 3060 PLA2G3/TNFAIP6/MT1G/ISG15/FASN/LIF/EVI2B/KLF2/BATF3/BATF2/IRF7/IL23A/CEACAM1/LRRC17/CSF3/IKZF1/CDKN2B/IL31RA/RELB/FOS/PRXL2A/CAMK4/CDKN1C/FLVCR1/PML/G6PD/TNF/FAM20C/VEGFA/STAT1/NFKBIA/GPR68/MAPK11/JUN/BATF/UBD/LGALS9/FSTL3/TLR2/MEF2C/TLR4/SH2B3/GLO1/IL11/ITGB8/INHBA/TFE3/MYC/IL34/CSF1/LYN/TRIB1/FLI1/PPARGC1B/GAB2/ETS1/IFI16/CTNNBIP1/KLF10/SLC11A2/CCN4/ADAR/SBNO2/SRF/PTPN2/F2RL1/ITGB6/CEBPG/PIP4K2A/BPGM/SRC/TFRC/JUNB/ZFP36/IL15/EPHA2/ZBTB46/CEBPB/MFHAS1/MYH9/TMOD3/FAM210B/FADD/KLF13/ERCC2/CASP8/PKNOX1/TIRAP/PTPN11/TGFBR2
GOBP_CENTROMERE_COMPLEX_ASSEMBLY 30 -0.6848709 -1.996767 0.0003783 0.0067426 0.0054405 648 H3-3A/CENPC/MIS18A/CENPH/CENPP/HELLS/CENPK/CENPF/OIP5/CENPE/DLGAP5/HJURP
GOBP_MITOTIC_SISTER_CHROMATID_COHESION 26 -0.7009907 -1.955982 0.0003765 0.0067426 0.0054405 1109 DSCC1/HASPIN/CDCA5/CDC20/SGO1
GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_MIGRATION 24 0.7315028 1.916119 0.0003776 0.0067426 0.0054405 1633 S100A7/CXCL10/CCL4/CCL20/CCL5/ADAM8/OXSR1/TNFSF14
GOBP_FATTY_ACYL_COA_METABOLIC_PROCESS 32 0.6869693 1.911677 0.0003776 0.0067426 0.0054405 3319 ELOVL6/ACSL1/NUDT8/HSD17B12/SLC25A1/ACSL4/ELOVL5/ELOVL7/ACACA/ELOVL1/ACOT7/HACD2/ACSL5/FAR2/ELOVL4/DGAT1/HACD1/FITM2/FAR1/PPT1
GOBP_B_CELL_ACTIVATION 184 0.4422579 1.637372 0.0003784 0.0067426 0.0054405 2605 NTRK1/CD70/THEMIS2/FZD9/LAT2/CLCF1/FOXP3/KLF6/BST2/VCAM1/HDAC9/IL4I1/TNFSF13B/TNFRSF13C/TICAM1/CARD11/LGALS1/BATF/TNFAIP3/MEF2C/TLR4/TNIP2/DOCK10/LRRC8A/CDKN1A/PTPRJ/IL11/INHBA/DNAJB9/LYN/IRS2/NOD2/PELI1/CTPS1/CD40/IL7R/PTPN2/SHLD1/SYK/ADAM17/SHLD2/CEBPG/MMP14/RNF168/BCL3/MALT1/GPS2/ST3GAL1/AHR/BAK1/TFRC/CMTM7/CD86
GOBP_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS 396 0.3708885 1.481330 0.0003742 0.0067426 0.0054405 2666 ACHE/ELOVL6/CDHR1/SGIP1/LPIN1/SCD/MLXIPL/ALOXE3/ACSL1/PCDH15/SCX/OAS1/SLC39A8/KDR/ALPL/CNGB1/IL1B/SERPINA3/PTGS2/CNR1/ADAMTS5/NR4A3/FOXC2/PECAM1/ADAM8/MFSD2A/CYP26B1/LIPA/CD34/SFN/ESAM/IL1A/FA2H/OCLN/TNF/ZG16B/BMP6/VEGFA/ACADL/SOX9/PRLR/ACACA/CLDN4/TMPRSS11F/TP53INP2/TNFAIP3/DDIT3/IL18R1/PTGES/ADRB2/TLR4/ATF4/ADIPOR2/VCL/MFAP2/ELOVL1/GRB10/TFE3/MET/CSF1/RAC3/PLCL1/ITGB3/PPARGC1B/LCN2/MYO5B/LPCAT1/PIWIL4/NOD2/CFTR/PPARGC1A/AKT3/SLC11A2/PDGFC/CDH3/SRF/METRNL/TJP1/ABCA12/SYK/ADAM17/CLDN12/ITGB6/P2RX4/LSR/SQSTM1/LAMC1/ABCA3/SLC12A2/KRAS/PIP/SRC/APBB2/IL4R/EGR1/GRHL1/ACADVL/TFRC/CLDN1/ACTB/IL15/HYAL2/NOVA1/TJP2
GOBP_POSITIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE 15 -0.8139781 -2.002999 0.0003809 0.0067618 0.0054560 1641 MAPK15/ANAPC4/CDT1/ESPL1/DLGAP5
GOBP_ANTIMICROBIAL_HUMORAL_RESPONSE 64 0.5613376 1.803637 0.0003853 0.0068140 0.0054981 758 DEFB4A/S100A7/CXCL10/CXCL11/CXCL9/PRSS3/S100A12/CXCL2/CXCL6/CXCL3/CXCL8/PI3/CXCL5/DEFB1/CXCL1/PGLYRP4/PF4V1/KLK7
GOBP_ANTIMICROBIAL_HUMORAL_IMMUNE_RESPONSE_MEDIATED_BY_ANTIMICROBIAL_PEPTIDE 43 0.6418616 1.889615 0.0003898 0.0068682 0.0055419 1012 DEFB4A/S100A7/CXCL10/CXCL11/CXCL9/S100A12/CXCL2/CXCL6/CXCL3/CXCL8/CXCL5/DEFB1/CXCL1/PGLYRP4/PF4V1/KLK7/PGLYRP3
GOBP_NEGATIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE 39 -0.6428854 -1.980237 0.0003926 0.0068741 0.0055467 1115 FBXO5/MAD1L1/TRIP13/CCNB1/ZWINT/CDT1/CENPF/TTK/MAD2L1/NDC80/PLK1/BUB1/BUB1B
GOBP_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE 76 0.5492611 1.797363 0.0003931 0.0068741 0.0055467 2798 RSAD2/FOXP3/IL1B/BST2/NR4A3/CAMK4/ARID5A/SEMA7A/TNF/TNFRSF1B/TICAM1/CD55/TGFB2/IL18R1/TLR4/CLEC7A/HLA-G/HLA-F/IRAK3/NOD2/BCL10/HLA-E/F2RL1/TRPM4/HMOX1/SPON2/TREM1/TRAF2/MALT1/SLC7A5/LACC1/IL1R1/IL18
GOBP_REGULATION_OF_CELL_MORPHOGENESIS 262 0.4106489 1.582147 0.0003977 0.0069284 0.0055904 3791 ARC/SYT2/SYT1/KDR/NTNG1/UNC13A/RND1/RELN/LRP8/SYT17/STRIP2/RNF157/OLFM4/FYN/MFSD2A/CDC42EP1/SPRY4/RHOB/FMNL3/VEGFA/GBP1/CLDN4/UNC13D/RND3/FGD2/NEDD9/PLEKHO1/MELTF/RHOF/DAPK3/PLXNA3/TRIOBP/MSN/DVL2/RAC3/GNA12/EPB41/DBN1/DAB2/PRAG1/EFNA5/RHOG/S100A10/NTNG2/CDC42EP3/ANXA1/PLXNA1/PARP6/DLC1/TPM1/SPAG9/PLXNA4/ILK/FLNA/FBLIM1/SRC/ATP10A/HEXB/RHOD/RHOC/PLAA/TACSTD2/ITSN2/ARPC2/DIAPH1/RHOBTB3/DAG1/RASAL1/FGD6/MYH9/DOCK5/CDC42EP5/P4HB/MYADM/SPARC/MYH14/MUL1/PDPN/SH3KBP1/CFL1/MAP3K13/FITM2/TESK1/ALDOA/CDC42SE1/HAS2/GRIP1/WASHC2C/MACF1/CRK/SMURF1/WDR1/RHOA/FGD4/RAC1/RAC2/STRIP1/PALM2AKAP2
GOBP_REGULATION_OF_RECEPTOR_RECYCLING 20 0.7665114 1.942323 0.0004042 0.0070165 0.0056615 1468 ACHE/PCSK9/LDLR/SNCA/ECE1/OPTN
GOBP_ENDOTHELIUM_DEVELOPMENT 108 0.5015915 1.738881 0.0004343 0.0075094 0.0060593 2022 CXCL10/DLL4/FASN/XDH/KDR/FOXP3/IL1B/CEACAM1/FOXC2/PECAM1/CLIC4/MYD88/CD34/TNF/BMP6/RHOB/VEGFA/FGF1/ACVRL1/RAP2B/HOXB5/ICAM1/VCL/PLOD3/MSN/ATOH8/MET/CSNK2B/FSTL1/COL22A1/ZEB1/F2RL1/TJP1
GOBP_CELL_CYCLE_G2_M_PHASE_TRANSITION 142 -0.4317744 -1.645693 0.0004372 0.0075318 0.0060774 1724 CIT/BRCA1/MRNIP/PKMYT1/CDC7/NEK10/STOX1/FBXO5/KDM8/ORC1/AURKA/CCNB1/ATAD5/BLM/CDC25C/CCNA2/CDC25A/CENPF/CLSPN/KIF14/MELK/TICRR/FBXL22/CDK1/NDC80/FOXM1/PLK1/CCNB2/DTL
GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY 142 0.4588213 1.643391 0.0004483 0.0076946 0.0062087 3181 RSAD2/OAS3/OASL/TNIP3/OAS1/LBP/IRF7/IFIH1/BIRC3/IRAK2/IFI35/MYD88/TNIP1/TNF/TICAM1/NFKBIA/RFTN1/SLC15A3/LGALS9/LY96/DDX60/TNFAIP3/TLR2/NMI/TLR4/TNIP2/CLEC7A/IRAK3/TYRO3/LYN/GFI1/NOD2/PELI1/BCL10/DHX58/CD40/IRAK1/PTPN22/TRIM25/F2RL1/RIPK2/NPLOC4/GPS2/SMPDL3B/NOD1/LACC1/S100A14/IRF1/MFHAS1/RTN4/DAB2IP/MAPKAPK2/SLC15A4/TIRAP/MAPKAPK3/FLOT1/RPS6KA3/CAV1
GOBP_POSITIVE_REGULATION_OF_HEMOPOIESIS 120 0.4921583 1.719163 0.0004710 0.0080550 0.0064995 3060 PLA2G3/TNFSF9/LIF/EVI2B/FOXP3/IL23A/FOS/IL4I1/ADAM8/CD83/SOCS1/IL1RL2/TNF/LGALS1/GPR68/VNN1/LGALS9/HLA-G/DUSP10/IL34/CSF1/CD46/NFKBIZ/TRIB1/PPARGC1B/IL15RA/NFKBID/SOX4/CTNNBIP1/IL7R/KLF10/TOX/ANXA1/PNP/SYK/MMP14/RIPK2/MALT1/IL4R/CD86/IL15/ZBTB46/IL18/FADD/ZBTB7B/CASP8/BTN2A2/TGFBR2
GOBP_INTERLEUKIN_2_PRODUCTION 47 0.6192443 1.852877 0.0004852 0.0082675 0.0066710 2605 FOXP3/IL1B/CD83/CD34/IL1A/LAG3/CARD11/GBP1/HOMER3/TNFAIP3/CLEC7A/PRKCQ/NOD2/ANXA1/PNP/HDAC7/RIPK2/TRAF2/MALT1/ZFP36/CD86
GOBP_HUMORAL_IMMUNE_RESPONSE 130 0.4701054 1.664495 0.0005032 0.0085127 0.0068688 1474 DEFB4A/S100A7/CXCL10/CXCL11/EBI3/CXCL9/PRSS3/S100A12/CXCL2/CXCL6/CXCL3/CXCL8/PI3/CXCL5/IL1B/DEFB1/CXCL1/PGLYRP4/PF4V1/CD83/KLK7/TNF/COLEC10/CD55/CFB/PGLYRP3/C4BPA/SPNS2/MEF2C/C1S/S100A9/RARRES2/TFE3/CD46
GOBP_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION 153 0.4558189 1.645000 0.0005032 0.0085127 0.0068688 3102 FGFBP1/DLL4/SLIT2/FGF2/MIR200A/KDR/HDAC9/THBS1/ZC3H12A/PTGS2/CEACAM1/SCARB1/EDN1/FOXC2/ANXA3/TNF/RHOB/VEGFA/FGF1/ACVRL1/PDGFB/MEF2C/RRAS/KLF4/ADAMTS9/ATOH8/MET/EGF/CSNK2B/ITGB3/WNT7A/LGMN/GADD45A/BMPER/SP100/ETS1/PLPP3/AKT3/CD40/ADGRB1/ANXA1/CARD10/ADAM17/HDAC7/P2RX4/HMOX1/BCAR1/TMSB4X/STAT5A/EPHA2/MAP3K3/MAP2K3/PIK3C2A/GLUL/DAB2IP/SRPX2/JUP/PLCG1/SPARC/GFUS
GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY 35 0.6641021 1.892955 0.0005055 0.0085199 0.0068746 2470 MICA/FOXP3/CEACAM1/IL4I1/CD55/LGALS9/C4BPA/SERPINB4/SERPINB9/HLA-G/KLRD1/HLA-F/CD46/NOD2/IL7R/HLA-E/HLA-B/AHR
GOBP_POSITIVE_REGULATION_OF_ION_TRANSPORT 181 0.4451013 1.647003 0.0005096 0.0085484 0.0068976 1177 PLA2G3/ARC/CXCL10/CXCL11/RGS7/CCL4/CXCL9/SCN3B/SYT1/SNCA/CCL5/LRRC55/IL1B/KMO/SCN1B/RELN/PRSS8/EDN1/CLTRN/GALR2/ANK2/IL1A/CX3CL1/G6PD/STXBP1/GLRX/TRPV3/PDGFB/PTGES/ADRB2/ATF4/PTAFR
GOBP_DOUBLE_STRAND_BREAK_REPAIR 258 -0.3725545 -1.515726 0.0005108 0.0085484 0.0068976 4164 SFPQ/SETD2/CIB1/RAD51B/TRRAP/MCM6/PNKP/KDM1A/MBTD1/BRCA2/OGG1/HPF1/REV3L/NSD2/ERCC4/RPA3/BRME1/PPP4R3B/RUVBL1/ZCWPW1/RADX/FIGNL1/MSH2/TIMELESS/ZSWIM7/NSMCE1/POT1/FEN1/ATM/PARPBP/MCM4/H2AX/C14orf39/MRE11/WRN/SMC6/RAD52/HMGB1/RMI1/KMT5C/GINS4/KDM4D/LIG3/MMS22L/RUVBL2/SLF1/EP400/WRAP53/MGMT/PAXX/FANCM/ERCC1/ABRAXAS1/HSF2BP/FMN2/XRCC3/BRCA1/MRNIP/POLN/CDC7/EME1/RMI2/IFFO1/MCMDC2/BRIP1/FANCB/HMGB2/TRIP13/WAS/BLM/DNA2/RAD51/RECQL4/XRCC2/GINS2/RAD51AP1/RAD51AP2/POLQ/FOXM1/RAD54B/RAD54L/ESCO2/CDCA5/DMC1/CDC45
GOBP_ACTIVATION_OF_IMMUNE_RESPONSE 214 0.4147664 1.563217 0.0005282 0.0088079 0.0071070 2469 ZBP1/THEMIS2/HMSD/LAT2/FOXP3/IL1B/CMTM3/ZC3H12A/CEACAM1/C5AR2/NR4A3/FYN/PLPP4/COLEC10/CARD11/CD55/GBP1/RFTN1/IKBKG/CD47/MICB/CFB/C4BPA/UBASH3A/MEF2C/TRIM5/TLR4/CLEC7A/KLRD1/PLSCR1/C1S/PTPRJ/DUSP3/CD276/CD46/LYN/NFKBIZ/BTN3A1/NFKBID/NOD2/IFI16/BCL10/PTPN22/PTPN2/RNF31/THY1/SYK/C8B/BCAR1/RIPK2/SRC/MALT1/PRKCH/GPS2/LPXN/RBCK1
GOBP_REGULATION_OF_MONOCYTE_CHEMOTAXIS 19 0.7615164 1.901587 0.0005330 0.0088562 0.0071460 2031 S100A7/CXCL10/SLIT2/CCL5/CCN3/SERPINE1/CXCL17/GREM1/LYN/LGMN/DUSP1/MOSPD2
GOBP_RESPONSE_TO_MECHANICAL_STIMULUS 158 0.4500563 1.630239 0.0005390 0.0089233 0.0072002 3060 NTRK1/CXCL10/PHF24/SLC8A1/TTN/SCX/HABP4/TNFRSF10A/FOSB/IL1B/ATP8A2/THBS1/CLCN6/PTGS2/STRA6/EDN1/FYN/FOS/MYD88/ANKRD1/MAP1B/TNF/BMP6/CHRNA10/STAT1/NFKBIA/SCEL/SOX9/JUN/PIEZO1/ENG/TLR4/JUND/CNTNAP2/TNFSF14/COL1A1/GADD45A/TMEM120A/BCL10/CD40/MAPK3/MMP14/CASP5/SERPINE2/SRC/FOSL1/FAS/SLC9A1/BAK1/CNN2/NFKB1/IRF1/ACTG1/DAG1/TNFRSF10B/FADD/TMC1/CASP8/JUP/ETV1/TGFBR2
GOBP_NEGATIVE_REGULATION_OF_NEURON_DEATH 165 0.4420679 1.620255 0.0005458 0.0089738 0.0072409 2346 PLA2G3/NTRK1/NES/FZD9/SNCA/SLC7A11/CLCF1/DRAXIN/NCOA7/CSF3/NR4A3/ADAM8/CD34/CX3CL1/TNFRSF1B/STXBP1/JUN/IKBKG/EN2/MEF2C/ATF4/HLA-F/AGAP2/CSF1/ATP13A2/TYRO3/FOXB1/CD200/LGMN/PPARGC1A/BOK/ISL1/NFATC4/AP2B1/NTRK2/PCDHGC3/HMOX1/TRAF2/KRAS
GOBP_DNA_RECOMBINATION 281 -0.3593186 -1.486766 0.0005440 0.0089738 0.0072409 3626 RPA3/BRME1/RUVBL1/ZCWPW1/RADX/MSH6/FIGNL1/MSH2/H1-3/TIMELESS/ZSWIM7/NSMCE1/FEN1/ATM/LIG1/H1-2/PARPBP/MCM4/ANKRD31/H2AX/C14orf39/MRE11/WRN/SMC6/RAD52/HMGB1/ALYREF/RMI1/KMT5C/HSPD1/GINS4/MSH3/KDM4D/LIG3/MMS22L/MSH5/RUVBL2/EP400/WRAP53/PSMC3IP/ENDOG/FANCM/ERCC1/HSF2BP/RNF212/ZRANB3/XRCC3/BRCA1/MRNIP/POLN/CDC7/TCF7/EME1/RMI2/HROB/LEF1/MCMDC2/BRIP1/FANCB/HMGB2/TRIP13/ATAD5/WAS/BLM/BCL11B/RAD51/RECQL4/XRCC2/GINS2/RAD51AP1/RAD51AP2/ZSCAN4/POLQ/RAD54B/CNTD1/EXO1/RAD54L/H1-5/H1-1/DMC1/CDC45/TOP2A
GOBP_SERTOLI_CELL_DEVELOPMENT 10 0.8571657 1.830064 0.0005492 0.0089977 0.0072601 884 NTRK1/IL1A/SOX9
GOBP_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION 51 -0.5763372 -1.863719 0.0005702 0.0093085 0.0075109 1115 XRCC3/MTBP/FBXO5/BMP7/MAD1L1/TRIP13/CCNB1/ZWINT/CDT1/CENPF/FBXO43/TTK/MAD2L1/NDC80/PLK1/BUB1/BUB1B
GOBP_SKIN_DEVELOPMENT 207 0.4259012 1.602370 0.0005806 0.0094128 0.0075951 2684 SPRR2E/SPRR2F/SPRR2A/S100A7/SPRR1A/PAX6/SPRR3/NSDHL/SPRR2D/ALOXE3/EREG/ATP8A2/DHCR24/FST/IVL/DKK1/CLIC4/CYP26B1/SFN/IL1A/FA2H/TNF/OVOL1/SCEL/SOX9/CLDN4/ERRFI1/ZBED2/KRT17/TGFB2/TRIM16/SPRR1B/FERMT1/INHBA/ELOVL1/ADAM9/MET/GJB3/OPN3/COL5A3/HOXC13/COL1A1/CDH3/SRF/ANXA1/ABCB6/ABCA12/ITGB6/SLC27A4/LSR/ITGA3/ST14/PRKCH/MSX2/MAP2K1/GRHL1/ZFP36/CLDN1/EPHA2/TRADD
GOBP_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS 264 0.3997466 1.536936 0.0005787 0.0094128 0.0075951 1340 PLA2G3/PNPLA3/APOC1/LIPC/LPIN1/LDLR/PLA2G4C/FGF2/LCAT/GPCPD1/SCARB1/SOCS2/PIP4P1/ABHD4/MFSD2A/GALR2/PCYT2/SOCS1/SELENOI/TMEM86B/ENPP6/SOCS3/LIPH/MTMR11/PI4K2A/PDGFB/PISD/GDPD3/PLSCR1/GPAT3/PLAAT1/PIGW/PGP
GOBP_RECEPTOR_RECYCLING 31 0.6807703 1.890148 0.0005833 0.0094138 0.0075959 1468 ACHE/PCSK9/LDLR/SNCA/PHETA2/ECE1/OPTN
GOBP_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE 62 0.5729497 1.822921 0.0005847 0.0094138 0.0075959 2252 PLA2G3/ITGAM/LAT2/LBP/CD177/NR4A3/IFI35/MYD88/ANXA3/TICAM1/DYSF/STXBP1/ADGRE2/UNC13D/LGALS9/NMI/PTAFR/STX4/LYN/GAB2/SBNO2/F2RL1/SYK/HMOX1
GOBP_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY 48 0.6168958 1.855775 0.0005877 0.0094167 0.0075983 3751 MICA/CEACAM1/SH2D1B/LAG3/UNC13D/LGALS9/SERPINB4/SERPINB9/RAET1E/ULBP1/HLA-G/KLRD1/HLA-F/PVR/ULBP3/CADM1/HLA-E/ULBP2/CEBPG/HLA-B/RAB27A/TUBB/NECTIN2/IL18/HLA-A/RNF19B/RAET1G/PLEKHM2/CRK/IL12A
GOBP_REGULATION_OF_HORMONE_SECRETION 159 0.4496869 1.629971 0.0005889 0.0094167 0.0075983 2245 PLA2G3/LIF/CCL5/ACSL4/IL1B/CCN3/CNR1/EDN1/AACS/RAB8B/TNF/BMP6/NOS2/GPR68/PCK2/FOXA2/C1QTNF1/FKBP1B/KLF7/LRRC8A/IL11/INHBA/PAX8/GPR27/ANO1/STX4/ADCY5/RAB11FIP1/IRS2/SLC8B1/DAB2/C1QTNF3/SOX4/CFTR/EFNA5/ZBED6/ISL1/FAM3D/ENSA/GABBR1/ANXA1/GLUD1/TRPM4/ABCA12/PFKFB2/STX1A/RAB11FIP5/DOC2B
GOBP_CELL_GROWTH 400 0.3648108 1.456704 0.0005988 0.0095422 0.0076995 2656 TMEM97/HYAL1/ADRA1A/SLIT2/DPYSL2/RTN4R/OLFM1/SYT2/L1CAM/SYT1/MEG3/MAP2/ISLR2/ROS1/DRAXIN/UNC13A/BST2/SEMA3B/CCN3/KIF26A/SYT17/CEACAM1/OSGIN1/RNF157/SOCS2/SEMA3D/EDN1/MFSD2A/SFN/SEMA7A/MAP1B/PML/FGF13/S100A8/G6PD/CXCL16/VEGFA/HBEGF/SOX9/SGK1/ACVRL1/HDAC6/KRT17/MELTF/TGFB2/WASF1/VCL/CDA/ENPP1/PRKCQ/CDKN1A/PTPRJ/GREM1/S100A9/PLXNA3/INHBA/NRCAM/CDKN2A/DBN1/SPHK1/DAB2/DCUN1D3/SLC9A6/EFNA5/SESN2/CLSTN3/SHTN1/SRF/PLXNA1/ADAM17/SPOCK1/MMP14/NDUFA13/SPAG9/PLXNA4/COBL/DCBLD2/BCAR1/SERPINE2/BTG1/TGFBR1/NTN1/SEMA3A/PLAA/ITSN2/IGFBP7/SLC9A1/PDLIM5/TFRC/SEMA3C/HYAL2/NDEL1
GOBP_T_CELL_MIGRATION 45 0.6164673 1.836174 0.0006068 0.0096372 0.0077762 2331 S100A7/CXCL10/CXCL11/CCL20/CCL5/ADAM8/CXCL16/RIPK3/ICAM1/OXSR1/MSN/CD200/TNFSF14/ITGB7/ADAM17/XG/SLC12A2
GOBP_REGULATION_OF_CELL_KILLING 59 0.5794385 1.811753 0.0006127 0.0096969 0.0078244 2242 CXCL6/MICA/ITGAM/IL23A/CEACAM1/LAG3/RIPK3/CD55/NOS2/LGALS9/SERPINB4/SERPINB9/RAET1E/TGFB2/ICAM1/CLEC7A/HLA-G/KLRD1/HLA-F/PVR/IL11/CADM1/IL7R/HLA-E/F2RL1/SYK/HLA-B
GOBP_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS 373 0.3748911 1.491130 0.0006223 0.0098162 0.0079206 3295 APOC1/HMGCR/PAX6/LPIN1/MLXIPL/TRIB3/SLIT2/SLC8A1/NTRK3/PTPRH/XDH/SNCA/IL1B/ZC3H12A/CEACAM1/CDKN2B/DKK1/UCHL1/CDKN1C/SFN/SOCS1/SPRY4/OCLN/TNF/WARS1/MASTL/JUN/PIK3IP1/SOCS3/FOXA2/BMP2/PMEPA1/TNFAIP3/ERRFI1/FKBP1B/ENG/GPRC5A/PDGFB/PTPRO/TGFB2/PARP14/CDA/SH2B3/ENPP1/DUSP6/CDKN1A/PTPRJ/SPRY1/GREM1/RUBCN/CHP1/INHBA/DUSP10/GRB10/NIBAN1/ANKLE2/INCA1/CAMK2N1/IRAK3/DUSP3/CDKN2A/LYN/DBNDD1/TRIB1/IRS2/TRIB2/GADD45A/MAPK8IP1/LPCAT1/PLPP3/MICAL1/CHMP6/PTPN22/DUSP1/ENSA/DDIT4/ADAR/PTPN2/TMEM225B/THY1/DUSP16/SPAG9/PIP4K2A/SMAD6/PRKRIP1/INPP5F/IGFBP3/YWHAG/BAK1/PIP4K2C/HYAL2/NCK1/TIGAR/SWAP70/PPIA/MFHAS1/DAB2IP/PID1/STK38/LATS2/MYADM/SPRED2/SMPD1/ARPP19/SIRPA/MGAT5/FLCN/SH3BP5/TWIST1/HEXIM1/CAV1/EIF4G1/TESK1/TRIM27/GNAI2
GOBP_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE 197 -0.4047889 -1.623068 0.0006273 0.0098611 0.0079568 1693 XRCC3/JADE1/BRCA1/MTBP/MRNIP/EME1/GPNMB/FBXO5/STK33/BTG4/GJC2/BMP7/EZH2/ORC1/MAD1L1/TRIP13/CCNB1/BLM/GAS1/ZWINT/CDT1/CENPF/CLSPN/E2F7/TTK/MAD2L1/TICRR/CDK1/NDC80/PLK1/BUB1/DTL/GTSE1/BUB1B
GOBP_REGULATION_OF_LEUKOCYTE_DEGRANULATION 33 0.6720917 1.885718 0.0006440 0.0100904 0.0081419 2437 PLA2G3/ITGAM/CEACAM1/CD177/STXBP1/ADGRE2/UNC13D/LGALS9/PTAFR/HLA-F/STX4/LYN/GAB2/F2RL1/SYK/HMOX1/IL4R
GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 118 0.4747687 1.654019 0.0006543 0.0102173 0.0082443 1400 PAX6/FGF2/XDH/LIF/ASCL1/MAFF/IL1B/CEACAM1/CDKN2B/SERPINE1/CDKN1C/SFN/IL1A/TNF/BMP6/VEGFA/STAT1/SOX9/PRLR/ACVRL1/ERRFI1/ZBED2/KLF7/TRIM16/VCL/SPRY1/PAX8/ATOH8
GOBP_MEIOTIC_SPINDLE_ORGANIZATION 13 -0.8239656 -1.962020 0.0006950 0.0108171 0.0087282 1115 FBXO5/AURKA/ESPL1/NDC80/CCNB2/ASPM
GOBP_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY 29 0.6829164 1.881266 0.0006990 0.0108426 0.0087488 3751 MICA/CEACAM1/SH2D1B/LAG3/LGALS9/SERPINB4/SERPINB9/RAET1E/HLA-G/KLRD1/HLA-F/PVR/CADM1/HLA-E/HLA-B/NECTIN2/HLA-A/RAET1G/CRK/IL12A
GOBP_REGULATION_OF_LYMPHOCYTE_CHEMOTAXIS 16 0.7745517 1.873806 0.0007264 0.0112308 0.0090620 2105 S100A7/CXCL10/CCL4/CCL5/OXSR1/TNFSF14/SLC8B1/ADAM17
GOBP_T_CELL_MEDIATED_IMMUNITY 77 0.5383706 1.759066 0.0007300 0.0112487 0.0090764 3379 CD70/RSAD2/MICA/FOXP3/IL1B/IL23A/CEACAM1/IL4I1/ARID5A/TNFRSF1B/RIPK3/CD55/RFTN1/IL18R1/ICAM1/HLA-G/KLRD1/HLA-F/PVR/CD46/CADM1/NOD2/IL7R/HLA-E/TRPM4/HLA-B/TRAF2/MALT1/RAB27A/AHR/NECTIN2/CTSC/IL1R1/IL18/FADD/HLA-A/BTN3A3/FZD5/EMP2/BTN3A2/MR1
GOBP_PYRIDINE_NUCLEOTIDE_METABOLIC_PROCESS 27 0.6907847 1.867006 0.0007468 0.0113981 0.0091970 1885 QPRT/IDO1/IDO2/KYNU/SLC5A8/KMO/NAMPT/PARP9/NUDT17/HAAO/NADK
GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY 70 0.5502025 1.792986 0.0007447 0.0113981 0.0091970 2437 PLA2G3/CXCL6/ITGAM/LAT2/CD177/NR4A3/CAMK4/MYD88/ANXA3/TICAM1/STXBP1/ADGRE2/UNC13D/LGALS9/SERPINB9/PTAFR/STX4/LYN/GAB2/HLA-E/F2RL1/SYK/ADAM17/HMOX1/SPON2/TREM1/IL4R
GOBP_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY 135 0.4667094 1.659587 0.0007495 0.0113981 0.0091970 3482 NTRK1/S100A12/IL1B/IRAK2/ADAM8/MYD88/CX3CL1/S100A8/TNF/RIPK3/TICAM1/CARD11/IKBKG/LGALS9/TLR2/TRIM21/RTKN2/IL18R1/TRIM5/TLR4/CLEC7A/TRIM14/PRKCQ/GREM1/S100A9/EIF2AK2/IRAK3/PSMA6/TRAF1/NOD2/SPHK1/BCL10/CD40/IRAK1/SLCO3A1/TRIM25/RNF31/CTH/RIPK2/TRIM22/TRAF2/MALT1/PRKCH/NOD1/RBCK1/TFRC/TRADD/RPS6KA4/PPIA/IL18/TIRAP/TRAF5/DDRGK1/FLOT1/CAV1/MAP3K13/TRIM27/ARHGEF2/CFLAR/RELA
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY 99 0.4889111 1.659328 0.0007475 0.0113981 0.0091970 2908 RSAD2/ITGAM/CLCF1/FOXP3/IL1B/IL23A/SH2D1B/CD177/CAMK4/ARID5A/TNF/LAG3/TICAM1/CD55/NOS2/RAET1E/IL18R1/PTAFR/CLEC7A/HLA-G/KLRD1/HLA-F/PVR/STX4/CADM1/NOD2/CD40/HLA-E/F2RL1/SHLD1/SHLD2/HLA-B/TRAF2/MALT1/TFRC/NECTIN2/IL1R1/IL18/C3/SHLD3/FADD
GOBP_EXTRACELLULAR_TRANSPORT 42 -0.6036004 -1.892113 0.0007653 0.0115816 0.0093451 3061 GAS8/NPHP3/KATNIP/TTLL1/STK36/DNAH11/SPAG6/ODAD4/DNAAF11/KIF27/AQP4/SPA17/DNAAF4/CCDC40/CFAP54/SPAG17/NME5/DAW1/DNAI1/SPEF2/CCDC39/DPCD/SPAG16/ROPN1L/RFX3/DNAH9/CFAP45/NEK10/DNAH1/DNAH5/CFAP43/CFAP221/DNAAF1/CFAP53
GOBP_RECOMBINATIONAL_REPAIR 155 -0.4193094 -1.626912 0.0007665 0.0115816 0.0093451 4164 SFPQ/SETD2/RAD51B/TRRAP/MCM6/KDM1A/MBTD1/BRCA2/REV3L/ERCC4/RPA3/RUVBL1/RADX/FIGNL1/TIMELESS/ZSWIM7/NSMCE1/FEN1/ATM/PARPBP/MCM4/H2AX/MRE11/WRN/SMC6/RAD52/RMI1/GINS4/KDM4D/LIG3/MMS22L/RUVBL2/EP400/WRAP53/FANCM/XRCC3/BRCA1/MRNIP/POLN/CDC7/RMI2/HROB/MCMDC2/FANCB/WAS/BLM/RAD51/RECQL4/XRCC2/GINS2/RAD51AP1/RAD51AP2/POLQ/RAD54B/RAD54L/DMC1/CDC45
GOBP_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION 11 0.8448268 1.842752 0.0007869 0.0118136 0.0095323 720 LUM/SERPINB7/FOXP3/THBS1/CX3CL1
GOBP_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION 11 0.8448268 1.842752 0.0007869 0.0118136 0.0095323 720 LUM/SERPINB7/FOXP3/THBS1/CX3CL1
GOBP_NECROTIC_CELL_DEATH 52 0.5856043 1.798427 0.0008166 0.0122196 0.0098599 5214 ZBP1/FZD9/BIRC3/OLFM4/TNF/RIPK3/MLKL/PELI1/ITPK1/BOK/TRAF2/FAS/RBCK1/CASP6/MAP3K5/FADD/CASP8/CAV1/GSDME/NINJ1/ARHGEF2/CFLAR/HEBP2/TP53/RIPK1/CYLD/ATG9A/PGAM5/TSPO/BAX/TLR3/ALKBH7/PPIF/NUPR1/ADPRS/NOL3/PYGL
GOBP_CILIUM_OR_FLAGELLUM_DEPENDENT_CELL_MOTILITY 104 -0.4684251 -1.706692 0.0008246 0.0122634 0.0098952 3461 KIF9/BBS4/CFAP20/DNAI3/ADCY3/DRC1/CATSPER2/SLC26A8/SPAG6/ARMC2/CFAP251/DNAAF11/TTLL9/CFAP47/CFAP46/HOATZ/TTLL3/BBS2/CFAP69/CFAP58/ENO4/CCDC40/GAS2L2/CFAP52/CFAP54/RSPH9/EFHC2/DRC7/DZIP1/CFAP157/TTC12/DNAI1/DNAH7/IQCG/SPEF2/CCDC39/DPCD/SPAG16/SLC22A16/TEKT3/ROPN1L/ROPN1B/CCDC65/CFAP206/TEKT2/TEKT1/RFX3/TTC21A/TCTE1/EFHC1/CFAP45/CFAP65/DNAH3/CFAP44/TEKT4/MNS1/TEKT5/DNAH6/DNAH1/DNAH5/CFAP43/DNAAF6/TTLL6/DNAH2/PLTP/CATSPERD/MEIG1/EPPIN
GOBP_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY 497 0.3480488 1.419701 0.0008247 0.0122634 0.0098952 3037 NTRK1/FGFR4/GRB14/DOK6/FGFBP1/SLC2A4/PLAUR/NTRK3/IFI6/FGF2/NCF1/XDH/SNCA/KDR/EREG/HHIP/ROS1/IGF2/IL1B/KLB/THBS1/CEACAM1/SOCS2/NAMPT/NR4A3/FYN/FOXC2/EPHA10/IL31RA/PPP2R5B/GDF15/EPHA3/SOCS1/AREG/SPRY4/FAM20C/VEGFA/HBEGF/SOX9/PRLR/SOCS3/FGF1/BMP2/NEDD9/SH3TC2/ERRFI1/GPRC5A/EIF2AK3/PDGFB/CSRNP1/FGFBP3/ANKS1B/WASF1/ADRB2/PTP4A3/SH2B3/ENPP1/PRKCQ/PTPRJ/SPRY1/GREM1/RHBDF2/GRB10/RARRES2/DUSP3/MET/SVEP1/FLRT2/EGF/CSF1/ESM1/TYRO3/LYN/FLT1/ITGB3/IRS2/KL/DOK4/NGEF/SHC2/COL1A1/GAB2/LGMN/PTPN12/MPZL1/MYO1C/EFNA5/CHMP6/DDIT4/LRIT3/MST1R/PDGFC/CDH3/PTPN2/NFATC4/NIBAN2/HAP1/SYK/ADAM17/NTRK2/BCAR3/SLC27A4/EPHB4/PIP4K2A/GAREM1/BCAR1/SRC/STAT5A/PTPN18/TGFA/IGFBP3/CCND3/F3/NRG1/PIP4K2C/EPHA2/NDEL1/NCK1/TRADD/WNT4/PIK3C2A/CAV2/RTN4/DAB2IP/PID1/MAPKAPK2/NEDD4/ZBTB7B/RUNX2/PLCG1/ITGA5/PTPN11/RHBDF1
GOBP_DNA_UNWINDING_INVOLVED_IN_DNA_REPLICATION 22 -0.7273444 -1.995971 0.0008343 0.0123661 0.0099781 932 MCM4/WRN/GINS4/GINS1/BLM/RAD51/RECQL4/GINS2/CDC45
GOBP_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS 218 0.4159581 1.576635 0.0008517 0.0125844 0.0101542 2172 ELOVL6/ACSS2/QPRT/ACLY/IDO1/CMPK2/ENTPD8/ACSL1/IDO2/SNCA/HSD17B12/SLC25A1/ME1/KYNU/SLC5A8/ACSL4/PANK3/PANK1/KMO/ELOVL5/NAMPT/ADCY10/ELOVL7/PARP9/NOS2/ACACA/CDA/GARS1/ELOVL1/MYC/ADCY4/HAAO/ADCY5/UCKL1/ANTKMT/PPARGC1A/CTPS1/NADK/UPP1/ACOT7/HACD2/PNP/ACSL5/ELOVL4
GOBP_POSITIVE_REGULATION_OF_CHEMOTAXIS 101 0.4913546 1.677422 0.0008590 0.0126524 0.0102091 2343 S100A7/CXCL10/CCL4/SLIT2/NTRK3/CXCL8/FGF2/KDR/CCL5/LBP/THBS1/IL23A/EDN1/SERPINE1/CXCL17/STX3/VEGFA/ARTN/LGALS9/PDGFB/OXSR1/RARRES2/MET/IL34/CSF1/STX4/TNFSF14/LGMN/SCG2/MAPK3/F2RL1/MOSPD2/TPBG/ADAM17/P2RX4/DAPK2/TMSB4X
GOBP_DEFENSE_RESPONSE_TO_BACTERIUM 154 0.4447197 1.607865 0.0008907 0.0130781 0.0105526 2699 DEFB4A/S100A7/ISG15/CCL20/S100A12/OAS3/CXCL6/MICA/OAS1/PI3/LBP/OAS2/DEFB1/HP/IL23A/ADAMTS5/PGLYRP4/SERPINE1/MYD88/GBP2/EMILIN2/ANXA3/KLK7/S100A8/TNF/NOS2/PGLYRP3/TLR2/TLR4/RNF213/S100A9/RARRES2/OPTN/LCN2/ARG2/SELP/NOD2/H2BC21/IL7R/GBP4/HLA-E/ADGRB1/BPIFA2/F2RL1/KRT6A/WFDC3/RNF31/SYK/ADAM17/SPON2/BCL3/RIPK2/TREM1/NLRP1/RNASE7/NOD1/RBCK1/EPHA2/S100A14/MARCHF2/CEBPB
GOBP_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY 118 0.4685812 1.632463 0.0008943 0.0130888 0.0105612 3033 RSAD2/MICA/CLCF1/FOXP3/IL1B/IL23A/CEACAM1/SH2D1B/IL4I1/ARID5A/TNF/TNFRSF1B/LAG3/RIPK3/CD55/LGALS9/C4BPA/SERPINB4/SERPINB9/RAET1E/IL18R1/HLA-G/KLRD1/HLA-F/PVR/CD46/CADM1/NOD2/CD40/IL7R/HLA-E/SHLD1/TRPM4/SHLD2/HLA-B/TRAF2/MALT1/AHR/TFRC/NECTIN2/IL1R1/IL18/C3/SHLD3/FADD/SLC15A4/HLA-A
GOBP_POSITIVE_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY 11 -0.8454535 -1.946142 0.0008974 0.0130939 0.0105654 155 CDC20B/PLK1/CDC20/UBE2C
GOBP_RESPONSE_TO_FUNGUS 27 0.6868591 1.856396 0.0009006 0.0130991 0.0105695 2811 ZBP1/S100A12/MYD88/S100A8/TLR4/CLEC7A/S100A9/RARRES2/BCL10/SYK/SPON2/MALT1/RNASE7/COTL1/BAK1/FAM3A
GOBP_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY 17 0.7689283 1.882653 0.0009152 0.0132698 0.0107073 2005 ISG15/OAS3/OAS1/NLRC5/USP18/MMP12/STAT2/ADAR/PTPN2
GOBP_LONG_CHAIN_FATTY_ACYL_COA_METABOLIC_PROCESS 20 0.7462146 1.890892 0.0009201 0.0133005 0.0107320 2545 ELOVL6/ACSL1/HSD17B12/ACSL4/ELOVL5/ELOVL7/ELOVL1/ACOT7/HACD2/ACSL5/FAR2/ELOVL4/DGAT1
GOBP_CELLULAR_RESPONSE_TO_HEAT 60 0.5722227 1.795924 0.0009421 0.0135767 0.0109549 2252 CXCL10/TCIM/THBS1/PTGS2/CD34/IL1A/HSPA6/FGF1/IER5/ANO1/LYN/SLC52A3/IRAK1/STAC/HMOX1
GOBP_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS 23 0.7114300 1.856931 0.0009620 0.0137776 0.0111170 768 QPRT/IDO1/IDO2/KYNU/SLC5A8/KMO/NAMPT/PARP9
GOBP_DNA_INTEGRITY_CHECKPOINT_SIGNALING 118 -0.4393844 -1.627748 0.0009600 0.0137776 0.0111170 1635 BRCA1/MRNIP/EME1/STK33/BRIP1/ORC1/E2F1/BLM/DNA2/CDT1/CLSPN/TICRR/CDK1/PLK1/CDC45/DTL/GTSE1
GOBP_INNER_DYNEIN_ARM_ASSEMBLY 16 -0.7686835 -1.918978 0.0009900 0.0140931 0.0113716 3340 DNAAF5/DNAI3/CFAP100/ZMYND10/DNAAF11/DNAAF4/CCDC40/CFAP73/DNAH7/CCDC39/TEKT2/DNAH1/DNAAF6/DNAAF1/DNAH2
GOBP_LEUKOCYTE_APOPTOTIC_PROCESS 84 0.5223690 1.737741 0.0009884 0.0140931 0.0113716 2563 IDO1/SLC7A11/CCL5/HSH2D/IRF7/TSC22D3/ADAM8/RIPK3/CD274/LGALS9/MEF2C/PRKCQ/SELENOS/CDKN2A/LYN/IRS2/ARG2/NOD2/BCL10/IL7R/ANXA1/PRELID1/ADAM17/PIP/ST3GAL1/FAS/BAK1
GOBP_CELL_ADHESION_MEDIATED_BY_INTEGRIN 67 0.5434258 1.757161 0.0010040 0.0142479 0.0114965 3082 LIF/ITGAM/CCL5/ITGA9/CCN3/PLAU/FOXC2/SERPINE1/ITGA10/PIEZO1/TGFB2/ICAM1/FERMT1/ITGB8/PODXL/ADAM9/CYP1B1/RAC3/LYN/ITGB3/ACER2/PLPP3/ITGB7/ITGAV/SYK/ADAM17/ITGB6/COL16A1/ITGA3/LPXN/EPHA2/SWAP70/MUC1/ITGB4/ITGA6/ITGA5/PTPN11/ITGB5
GOBP_ENTRY_INTO_HOST 121 0.4633653 1.621410 0.0010146 0.0143545 0.0115825 3406 LDLR/IFITM1/CXCL8/NPC1/SCARB1/IFITM3/LAMP3/CLDN9/TRIM31/LGALS1/CD55/LGALS9/TRIM21/TRIM5/ICAM1/PLSCR1/TRIM14/PVR/SLC3A2/NECTIN4/CD46/TYRO3/TPCN2/ITGB3/ACE2/SLC52A2/ITGB7/TRIM25/KRT6A/ITGAV/ITGB6/IFITM2/TRIM22/SRC/TFRC/LY6E/CLDN1/CD86/EPHA2/NECTIN2/HYAL2/DAG1/CAV2/P4HB/RNASEK/SMPD1/VPS18/ITGA5/ITGB5/CAV1/TRIM27/EXOC2/SLC1A5/SLC52A1
GOBP_REGULATION_OF_ION_TRANSPORT 445 0.3479130 1.402809 0.0010179 0.0143589 0.0115861 1603 PLA2G3/ARC/PCSK9/CXCL10/CXCL11/GEM/RGS7/CLIC3/CCL4/CXCL9/SCN3B/KCNH8/SLC8A1/CACNB1/SYT2/SYT1/SNCA/MAPK8IP2/CCL5/LRRC55/IL1B/KMO/SCN1B/RELN/CLIC2/SYT17/PRSS8/PTGS2/CNR1/NOX1/CATSPER3/EDN1/FYN/PLPP4/CLTRN/CLIC4/STC2/FXYD6/GALR2/HVCN1/ANK2/IL1A/CX3CL1/PML/FGF13/G6PD/TNF/STXBP1/GLRX/KCNK15/CACNA2D4/HOMER3/JPH3/FKBP1B/FXYD5/TRPV3/PDGFB/ANO9/PTGES/MEF2C/ADRB2/ATF4/PTAFR/CBARP/CACNG8/REM1/CHP1/OXSR1/EGF/LYN/TPCN2/ITGB3/KCND3/ACE2/EPB41/KCNS3/ANTKMT
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION 19 0.7458595 1.862490 0.0010381 0.0145190 0.0117153 2437 PLA2G3/ITGAM/CD177/STXBP1/PTAFR/HLA-F/STX4/GAB2/F2RL1/SYK/IL4R
GOBP_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR 82 0.5267599 1.747361 0.0010386 0.0145190 0.0117153 1653 HYAL1/FGFR4/FGFBP1/DLL4/NR4A1/CXCL8/FGF2/CCL5/HHIP/KLB/THBS1/SPRY4/FAM20C/FGF1/FGFBP3/IER2/SPRY1/MYC/FLRT2/KL/COL1A1
GOBP_ANION_TRANSPORT 360 0.3656735 1.451474 0.0010326 0.0145190 0.0117153 2427 PLA2G3/GABRA4/SLC26A9/SLC2A6/CLIC3/ANO4/SNCA/SLC39A8/SLC7A11/SLC25A1/SLC5A1/SLCO4C1/SLC26A4/SLC5A8/SLC7A9/SLC16A13/IL1B/KMO/SLCO4A1/SLC6A11/CLIC2/SLC2A3/CLCN6/CEACAM1/SLC26A6/EDN1/CLTRN/CLIC4/SLCO1B1/MFSD2A/SLC16A4/SLC9A4/IL1A/SLC6A14/TNF/SLC13A5/NOS2/STXBP1/SLC20A1/GRM1/CLDN4/CD47/ANO2/APOL1/SLC9A2/SLC16A3/SLC10A6/SLC9A3/SLC25A23/ANO9/PTGES/ATF4/PTAFR/ENPP1/LRRC8A/PACC1/SLC25A25/ANO10/SLC4A3/MPC1/SLC3A2/ANO1/PRAF2/MYC/ACE2/SLC12A4/SLC52A2/SLC52A3/SLC7A7/SLC9A6/CFTR/SLC25A21/SLCO3A1/ANO7/SLC1A4/GABBR1/ANXA1/GIPC1/SLC10A3/SYK/GLRA2/NTRK2/P2RX4/SLC5A5/SLC27A4/SLC5A12/TG/SLC7A1/SLC12A2/MGST1/LRRC8C/SLC7A5/SLC5A6/SLC9A7/CYB5R1/SLC27A5
GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS 63 0.5438866 1.741602 0.0010453 0.0145693 0.0117558 2160 ISG15/SLIT2/OAS3/OAS1/IL1R2/CCL5/NLRC5/USP18/IL1RN/PARP14/SH2B3/KLF4/IRAK3/MMP12/PALM3/STAT2/RFFL/ADAR/PTPN2/F2RL1/PXDN/MAPK7
GOBP_PROGRAMMED_NECROTIC_CELL_DEATH 40 0.6131173 1.783376 0.0010560 0.0146735 0.0118399 5214 ZBP1/FZD9/BIRC3/TNF/RIPK3/MLKL/PELI1/ITPK1/BOK/TRAF2/FAS/RBCK1/CASP6/MAP3K5/FADD/CASP8/CAV1/ARHGEF2/CFLAR/TP53/RIPK1/CYLD/PGAM5/BAX/TLR3/ALKBH7/PPIF/NUPR1/ADPRS/PYGL
GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY 41 0.6139391 1.788920 0.0010732 0.0148689 0.0119976 2470 MICA/FOXP3/BST2/CEACAM1/IL4I1/CD55/LGALS9/C4BPA/SERPINB4/SERPINB9/HLA-G/KLRD1/HLA-F/CD46/NOD2/IL7R/HLA-E/HLA-B/HMOX1/AHR
GOBP_NEGATIVE_REGULATION_OF_CELL_KILLING 17 0.7647784 1.872493 0.0010800 0.0149194 0.0120383 2242 MICA/CEACAM1/LGALS9/SERPINB4/SERPINB9/HLA-G/KLRD1/HLA-F/IL7R/HLA-E/HLA-B
GOBP_NEGATIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS 25 0.7014195 1.850522 0.0010887 0.0149634 0.0120738 884 APOC1/INSIG1/TRIB3/CNR1/CEACAM1/MFSD2A/ACADL/SOX9
GOBP_CELL_KILLING 103 0.4864908 1.668480 0.0010896 0.0149634 0.0120738 2908 DEFB4A/S100A12/CXCL6/MICA/ITGAM/IL23A/CEACAM1/PGLYRP4/MYD88/LAG3/RIPK3/CD55/NOS2/UNC13D/LGALS9/PGLYRP3/SERPINB4/SERPINB9/RAET1E/TGFB2/ICAM1/CLEC7A/ULBP1/HLA-G/KLRD1/HLA-F/PVR/IL11/ULBP3/CADM1/IL7R/HLA-E/ULBP2/F2RL1/SYK/CEBPG/HLA-B/TREM1/RAB27A/TUBB/NECTIN2/CTSC/IL18/C3/FADD
GOBP_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY 221 0.4075309 1.543630 0.0011216 0.0153573 0.0123917 3880 NTRK1/RGS7/CCL22/CCL4/CCL20/RGS16/RTN4R/NTRK3/ADPRH/CCL5/CX3CL1/RASGRP3/TBC1D3D/ARHGAP11B/NEDD9/SNX9/DOCK10/ADAP2/TIAM2/DVL2/ASAP3/NGEF/CCL17/CD40/GMIP/RHOG/RGS10/S100A10/F2RL1/ARHGAP27/THY1/TBC1D4/BCAR3/RAP1GAP/SLC27A4/DOCK6/MAP4K4/ADAP1/SYDE2/MAPRE2/RSU1/RAPGEF3/SYDE1/EPHA2/NDEL1/TBC1D25/TBC1D10A/ASAP2/WNT4/SOS2/CAV2/RAP1GAP2/ITGA6/FLCN/GRHL3/RANGAP1/ARHGEF5/TBC1D22B/TBC1D10B/ARHGAP29/TBC1D17/TBC1D1/BIN1/TGM2/PICALM/CRK/HRAS/RGP1/RGS14/SGSM3/ARHGEF10/RAPGEF1/CHN1/GSK3B/PIP5K1A/MMUT/CORO1C/TBC1D20
GOBP_NEGATIVE_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS 13 0.8140413 1.874699 0.0011399 0.0155172 0.0125206 826 APOC1/INSIG1/TRIB3/CEACAM1/ACADL
GOBP_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY 52 0.5765706 1.770684 0.0011399 0.0155172 0.0125206 2384 CCL5/LBP/IL1B/SCARB1/IRAK2/MYD88/CX3CL1/TNF/BMP6/TICAM1/CD55/NFKBIA/LY96/TNFAIP3/TLR2/TRIM5/TLR4/PTAFR/LYN/TRIB1/BCL10/IRAK1/PTPN22/MAPK3/RIPK2/MALT1
GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY 195 0.4167784 1.549743 0.0011837 0.0160655 0.0129631 3461 CD70/RSAD2/MICA/CLCF1/FOXP3/IL1B/IRF7/IL23A/CEACAM1/SH2D1B/IL4I1/ARID5A/MYD88/TNF/TNFRSF1B/LAG3/RIPK3/CD55/RFTN1/BATF/UNC13D/LGALS9/C4BPA/SERPINB4/SERPINB9/RAET1E/IL18R1/ICAM1/ULBP1/HLA-G/KLRD1/C1S/HLA-F/PVR/CD46/ULBP3/CADM1/HLA-DOB/NOD2/BCL10/CD40/IL7R/HLA-E/ULBP2/SHLD1/TRPM4/C8B/SHLD2/CEBPG/RNF168/HLA-B/BCL3/TRAF2/MALT1/IL4R/RAB27A/AHR/TUBB/TFRC/NECTIN2/CTSC/IL1R1/SWAP70/C2/IL18/C3/SHLD3/FADD/SLC15A4/HLA-A/HLA-DMA/BTN3A3/FZD5/RNF19B/EMP2/MAD2L2/BTN3A2/MR1/RAET1G/PLEKHM2
GOBP_FATTY_ACYL_COA_BIOSYNTHETIC_PROCESS 21 0.7312148 1.864036 0.0012479 0.0168879 0.0136266 2172 ELOVL6/ACSL1/HSD17B12/SLC25A1/ACSL4/ELOVL5/ELOVL7/ACACA/ELOVL1/HACD2/ACSL5/ELOVL4
GOBP_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION 139 0.4434036 1.582783 0.0013004 0.0175476 0.0141589 3034 MUC21/FGL2/IDO1/FOXP3/ZC3H12A/CEACAM1/IL4I1/IL1RN/SOCS1/BMP6/VEGFA/LAG3/CD274/BMP2/LGALS9/C1QTNF1/FXYD5/ASS1/SH2B3/HLA-G/KLF4/PODXL/ADTRP/DUSP3/PRKG1/ARG2/PELI1/PTPN22/ANXA1/PTPN2/PDE5A/ABCA12/CD9/MAPK7/SERPINE2/IL4R/CD86/SWAP70/CEBPB/IRF1/EPCAM/CDH1/ZBTB7B/MYADM/BTN2A2
GOBP_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS 12 0.8170587 1.842869 0.0013133 0.0175691 0.0141763 2109 IDO1/IDO2/KYNU/KMO/IL4I1/HAAO/QDPR
GOBP_HOMOTYPIC_CELL_CELL_ADHESION 74 0.5305467 1.730276 0.0013086 0.0175691 0.0141763 3146 PLAUR/SLC7A11/CCL5/CEACAM1/PEAR1/CEACAM5/EMILIN2/DSC2/STXBP1/RAP2B/C1QTNF1/VCL/MYL9/SH2B3/PRKCQ/TYRO3/LYN/PRKG1/DSG2/ITGB3/PLPP3/CSRP1/MYL12A/SYK/CD9/XG/ILK/SERPINE2/FLNA/ACTB/TJP2/ACTG1/PPIA/MYH9/JUP/JAK1/PDPN
GOBP_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC 128 -0.4341052 -1.626075 0.0013115 0.0175691 0.0141763 513 H3C10/EZH2/HELLS/XIST/H3C7/DIRAS3/H3C12/LHX2/H3C3/H3C8/H3C2
GOBP_PHOSPHATIDYLCHOLINE_METABOLIC_PROCESS 57 0.5726279 1.785098 0.0013223 0.0176396 0.0142332 1887 PLA2G3/APOC1/LIPC/LDLR/PLA2G4C/LCAT/SCARB1/ABHD4/MFSD2A/TMEM86B/GDPD3/PLAAT1/LPCAT1/GPAT4/PLA2G15
GOBP_RESPONSE_TO_INTERFERON_BETA 24 0.6990071 1.830999 0.0013274 0.0176569 0.0142471 3624 IFITM1/OAS1/XAF1/BST2/IFITM3/STAT1/IKBKE/PLSCR1/SHFL/IFI16/NDUFA13/IFITM2/CAPN2/IRF1/PNPT1/CDC34/AIM2
GOBP_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS 52 0.5727748 1.759027 0.0013663 0.0181230 0.0146233 2664 ELOVL6/ACSL1/NUDT8/HSD17B12/SLC25A1/GGT7/ACSL4/ELOVL5/GGT5/AACS/ELOVL7/ACACA/ACSS3/ELOVL1/ACOT7/HACD2/ACSL5/FAR2/ELOVL4/SLC27A5/DGAT1/PAM
GOBP_EXTERNAL_ENCAPSULATING_STRUCTURE_ORGANIZATION 236 0.3987374 1.521086 0.0013814 0.0182711 0.0147427 2974 LUM/FGFR4/NOXO1/SCX/SLC39A8/HSD17B12/MMP25/MMP16/MMP10/NTNG1/SMOC1/MMP17/COL13A1/ADAMTS14/NOX1/ADAMTS5/FOXC2/NFKB2/ADAM8/KLK7/TNF/TNFRSF1B/MMP19/SOX9/ERO1A/LAMB3/LOXL2/BMP2/CAPG/ENG/MELTF/TGFB2/MMP15/COLGALT2/CCN1/COL9A2/GREM1/ADAMTS9/FERMT1/PLOD3/VIT/LCP1/ADTRP/FOXF2/CYP1B1/FLRT2/MMP7/PHLDB2/COLGALT1/MMP12/COL5A3/FMOD/COL1A1/COL22A1/MMP13/MIA/NTNG2/COL8A2/CTSV/SERPINF2/PXDN/COL12A1/MMP24/FURIN/SERPINH1/TGFBI/MMP14/ADAMTS1/PBXIP1/COL16A1/LAMC1/BCL3/COL17A1/TGFBR1/COL24A1/SPINT1/SH3PXD2B/THSD4/VIPAS39/TLL1/DAG1/MMP11/CAV2/FAP/OLFML2A/NTN4/ERCC2/NID2
GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE 90 0.5072647 1.699856 0.0014015 0.0184851 0.0149155 3033 RSAD2/CLCF1/IL1B/NR4A3/CAMK4/ARID5A/SEMA7A/KLK7/TICAM1/CD55/IL18R1/TLR4/CLEC7A/HLA-G/HLA-F/DNAJB9/STX4/NOD2/BCL10/CD40/HLA-E/PTPN22/F2RL1/SHLD1/SHLD2/SPON2/TRAF2/MALT1/SLC7A5/IL4R/TFRC/CD86/LACC1/IL1R1/IL18/SHLD3/HLA-A
GOBP_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION 50 -0.5627564 -1.803521 0.0014208 0.0186870 0.0150784 2665 GINS4/LIG3/DBF4B/ENDOG/RFC3/ZRANB3/GMNN/CDC7/FBXO5/DSCC1/MCIDAS/GINS1/BLM/GINS2/CDT1/E2F7/TICRR
GOBP_LEUKOCYTE_DEGRANULATION 50 0.5885403 1.780876 0.0014652 0.0192169 0.0155060 2462 PLA2G3/ITGAM/LAT2/CEACAM1/CD177/NR4A3/ANXA3/STXBP1/ADGRE2/UNC13D/LGALS9/PTAFR/HLA-F/STX4/LYN/GAB2/F2RL1/SYK/HMOX1/IL4R/RAB27A
GOBP_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE 140 0.4546879 1.630152 0.0014921 0.0195144 0.0157460 2541 NTRK1/S100A7/ADRA1A/FGFR4/CCL22/CCL4/CCL20/NTRK3/FGF2/KDR/CCL5/CAVIN3/C5AR2/CXCL17/SEMA7A/IL1A/CX3CL1/TNF/JUN/FGF1/BMP2/LGALS9/PDGFB/TLR4/ICAM1/ABCA7/AKAP12/BMPER/CCL17/NOD2/PTPN22/PDGFC/MAPK3/F2RL1/SERPINF2/TPBG/NTRK2/GAREM1/RIPK2/SRC/NOD1/MAP2K1/PDE8A/NRG1
GOBP_RESPONSE_TO_ACID_CHEMICAL 105 0.4781684 1.644900 0.0015180 0.0197980 0.0159748 2472 PNPLA3/NTRK1/KLF2/EDN1/FYN/SOCS1/TNF/VEGFA/MTHFR/COL6A1/ASS1/MYC/CASTOR1/LYN/COL1A1/SESN2/PDGFC/ZEB1/GLRA2/NTRK2/COL16A1/CAPN2/RRAGC
GOBP_TRIGLYCERIDE_BIOSYNTHETIC_PROCESS 29 0.6636183 1.828104 0.0015334 0.0199421 0.0160911 1290 PNPLA3/LPIN1/LDLR/ACSL1/SCARB1/MFSD2A/PCK2/GPAT3
GOBP_REGULATION_OF_T_CELL_PROLIFERATION 125 0.4617792 1.619840 0.0015578 0.0202040 0.0163024 3060 EBI3/CD70/IDO1/TNFSF9/CCL5/IGF2/FOXP3/IL1B/VCAM1/IL23A/IL4I1/TNFSF13B/IL1A/TNFRSF13C/TNFRSF1B/RIPK3/CARD11/CD55/CD274/LGALS9/HLA-G/PRKCQ/CD276/CD46/ARG2/MAPK8IP1/PELI1/HLA-E/PTPN22/ANXA1/PDE5A/PNP/SYK/RIPK2/SLC7A1/TYK2/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/SOS2/IL18/FADD/ZBTB7B/HLA-A/BTN2A2/TGFBR2
GOBP_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE 120 0.4682442 1.635628 0.0016030 0.0207321 0.0167285 3033 RSAD2/CLCF1/FOXP3/IL1B/BST2/NR4A3/CAMK4/ARID5A/SEMA7A/KLK7/TNF/TNFRSF1B/TICAM1/CD55/TGFB2/IL18R1/TLR4/CLEC7A/HLA-G/HLA-F/DNAJB9/IRAK3/STX4/NOD2/BCL10/CD40/HLA-E/PTPN22/F2RL1/SHLD1/TRPM4/SHLD2/HMOX1/SPON2/TRAF2/MALT1/SLC7A5/IL4R/TFRC/CD86/LACC1/IL1R1/IL18/SHLD3/SLC15A4/HLA-A
GOBP_HOMOLOGOUS_CHROMOSOME_SEGREGATION 43 -0.5842008 -1.842492 0.0016137 0.0208126 0.0167935 2420 NDC1/MSH5/PSMC3IP/CENPC/RNF212/FMN2/SYCP2/BRIP1/CCNE1/TRIP13/MAJIN/PTTG1/SGO2/ESPL1/CCNE2/PLK1/DMC1/SGO1
GOBP_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA 203 0.4085066 1.526698 0.0016217 0.0208583 0.0168303 3215 NREP/SCX/THBS1/PEG10/CDKN2B/EDN1/FYN/FOS/GDF15/CDKN1C/ANKRD1/LTBP2/PML/SOX9/JUN/ACVRL1/BMP2/ZEB2/SMAD9/PMEPA1/ENG/TGFB2/MEF2C/TGFB1I1/SPRY1/FERMT1/ITGB8/ADAM9/WNT7A/PTPRK/FMOD/COL1A1/DAB2/FNDC4/LTBP1/VEPH1/ZEB1/GIPC1/ADAM17/FURIN/ITGB6/MAPK7/SMAD6/ITGA3/TGFBR1/SRC/LPXN/IL17RD/LRG1/CLDN1/VASN/HYAL2/WNT4/CAV2/ID1/LATS2/SPRED2/ZMIZ2/TGFBR2/ITGB5/FLCN/CAV1/WNT10A/RUNX3
GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION 15 0.7867733 1.867785 0.0016325 0.0209406 0.0168967 3060 EBI3/IL23A/CD55/LGALS9/HLA-E/PTPN22/SYK/RIPK2/TYK2/IL18/HLA-A/TGFBR2
GOBP_HEAT_GENERATION 14 0.7948442 1.849892 0.0016707 0.0213706 0.0172437 1164 IL1B/PTGS2/CNR1/IL1A/TNF/PTGES/ADRB2
GOBP_NEURON_DEATH 288 0.3805995 1.472442 0.0017543 0.0223788 0.0180573 2543 PLA2G3/NTRK1/PCSK9/NES/FZD9/MIR200A/ITGAM/SNCA/SLC7A11/ASCL1/CCL5/CLCF1/DRAXIN/DHCR24/NCOA7/KMO/CSF3/NR4A3/FYN/DKK1/FOS/ADAM8/CD34/CX3CL1/G6PD/TNF/TNFRSF1B/STXBP1/JUN/IKBKG/EN2/DDIT3/TGFB2/MEF2C/TLR4/ATF4/HLA-F/CHP1/AGAP2/CSF1/ATP13A2/TYRO3/FOXB1/SIGMAR1/CD200/LGMN/PPARGC1A/BOK/ISL1/BID/DDIT4/NFATC4/AP2B1/NTRK2/PCDHGC3/HMOX1/TRAF2/CAPN2/NLRP1/KRAS/FAS/HYOU1/CASP7/EGR1/SLC9A1
GOBP_LONG_CHAIN_FATTY_ACYL_COA_BIOSYNTHETIC_PROCESS 15 0.7850939 1.863798 0.0017619 0.0223977 0.0180725 2172 ELOVL6/ACSL1/HSD17B12/ACSL4/ELOVL5/ELOVL7/ELOVL1/HACD2/ACSL5/ELOVL4
GOBP_PEPTIDE_CROSS_LINKING 23 0.6945966 1.812993 0.0017653 0.0223977 0.0180725 1424 SPRR2E/SPRR1A/SPRR3/PI3/THBS1/IVL/TGM4/SPRR1B/ABCA7
GOBP_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS 26 0.6784571 1.810836 0.0017774 0.0224295 0.0180981 3998 IDO1/CCL5/TSC22D3/ADAM8/RIPK3/CD274/LGALS9/PRKCQ/ARG2/IL7R/PRELID1/PIP/ST3GAL1/FADD/BMP4/HIF1A/RAG1/TP53
GOBP_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION 98 -0.4595980 -1.663244 0.0017770 0.0224295 0.0180981 1635 BRCA1/MRNIP/CDC7/NEK10/STOX1/FBXO5/ORC1/AURKA/CCNB1/ATAD5/BLM/CDC25C/CDC25A/CENPF/CLSPN/KIF14/TICRR/CDK1/PLK1/DTL
GOBP_CELL_CYCLE_DNA_REPLICATION 41 -0.5776279 -1.810220 0.0017990 0.0226408 0.0182686 1540 GMNN/CDC7/FBXO5/GINS1/ATAD5/BLM/DNA2/RAD51/CDT1/E2F7/CDC45
GOBP_POSITIVE_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY 38 0.6220897 1.794766 0.0018127 0.0227518 0.0183582 1440 ARC/NCF1/EREG/RELN/EDN1/AREG/HBEGF/HDAC6/ADRB2/GREM1/EGF
GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_HOST 157 0.4383808 1.589312 0.0018311 0.0229211 0.0184948 3406 LDLR/IFITM1/IFIT1/CXCL8/NPC1/SCARB1/IFITM3/LAMP3/CLDN9/TRIM31/LGALS1/CD55/LGALS9/TRIM21/TRIM5/ICAM1/PLSCR1/TRIM14/PVR/SLC3A2/NECTIN4/CD46/TYRO3/TPCN2/CHMP7/ITGB3/ACE2/THOC6/SLC52A2/CHMP6/ITGB7/TRIM25/KRT6A/ITGAV/ITGB6/IFITM2/TRIM22/SRC/VPS37B/TFRC/LY6E/CLDN1/CD86/EPHA2/NECTIN2/HYAL2/PPIA/DAG1/CAV2/P4HB/RNASEK/SMPD1/VPS18/ITGA5/ITGB5/CAV1/CHMP1B/TRIM27/EXOC2/SLC1A5/CHMP4C/SLC52A1
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS 66 0.5513975 1.775465 0.0018364 0.0229254 0.0184983 2105 S100A7/CXCL10/CCL4/CXCL8/CCL5/LBP/THBS1/IL23A/EDN1/SERPINE1/CXCL17/VEGFA/LGALS9/OXSR1/RARRES2/IL34/CSF1/TNFSF14/LGMN/MAPK3/F2RL1/MOSPD2/ADAM17
GOBP_DNA_REPLICATION_CHECKPOINT_SIGNALING 16 -0.7544040 -1.883330 0.0018440 0.0229593 0.0185256 828 ORC1/DNA2/CDT1/CLSPN/TICRR/CDC45
GOBP_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS 42 0.6075937 1.781879 0.0018527 0.0230058 0.0185632 2425 IDO1/CCL5/HSH2D/TSC22D3/ADAM8/RIPK3/CD274/LGALS9/PRKCQ/LYN/IRS2/ARG2/BCL10/IL7R/PRELID1/PIP/ST3GAL1
GOBP_ANTIVIRAL_INNATE_IMMUNE_RESPONSE 15 0.7830219 1.858879 0.0018588 0.0230210 0.0185754 255 CXCL10/IFIT1/OAS1/MX1
GOBP_PROTEIN_LOCALIZATION_TO_CILIUM 66 -0.5150113 -1.746731 0.0018667 0.0230577 0.0186050 4445 INPP5E/CDK20/GAS8/TMEM107/ATP6V1D/ARL6/ARL13B/DNAH11/TUB/ROM1/ARL3/WDR19/BBS4/BBIP1/TCTN2/ZMYND10/ODAD4/DZIP1L/TBC1D32/BBS9/DNAAF11/SPATA7/TCTN1/CFAP58/CCDC66/EFCAB7/IFT122/IFT140/CCDC88A/LZTFL1/WDR35/DZIP1/CC2D2A/CCDC39/IFT80/MAPK15/ROPN1B/TTC21A/DYNC2H1/TTC21B/CROCC
GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION 175 0.4195424 1.544046 0.0019135 0.0235734 0.0190211 3060 EBI3/CD70/IDO1/TNFSF9/CCL5/CLCF1/IGF2/FOXP3/IL1B/BST2/VCAM1/IL23A/IL4I1/MYD88/TNFSF13B/IL1A/TNFRSF13C/TNFRSF1B/RIPK3/TICAM1/CARD11/CD55/CD274/LGALS9/TNFAIP3/MEF2C/TLR4/HLA-G/PRKCQ/CDKN1A/GREM1/CD276/IL34/CSF1/CD46/LYN/IRS2/ARG2/MAPK8IP1/PELI1/CD40/HLA-E/PTPN22/MAPK3/ANXA1/PDE5A/PNP/SYK/RIPK2/SLC7A1/TYK2/AHR/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/SOS2/IL18/FADD/ZBTB7B/TIRAP/HLA-A/BTN2A2/TGFBR2
GOBP_CYTOPLASMIC_TRANSLATION 142 -0.4074974 -1.553162 0.0019413 0.0238527 0.0192465 4600 MIF4GD/RPL10/RWDD1/RPS11/RPS26/DPH5/RPL18/RPS16/RPL18A/RPS24/RPL23A/RPL24/EIF4A2/RPS5/NEMF/RPS27/RPS12/RPL27/EIF3D/RPL9/RPS8/RPL7A/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/ZNF385A/RPL41/RPL27A/RPL37A/RPL34/RPS15A/RPS28/PABPC1/RPS29/RPL3/RPS2/RPS20/RPS13/RPL29/RPS23/RPL11/CPEB3/RPS25/DPH6/RPL4/RPL30/RPL21/RPL23/RPL31/RPL13A/RPL32/RPL35A/RPL26L1/EIF2D/RPS6/RPSA/RPS4X/RPL15/RPS7/RPL6/RPL37/RPS18/RPL22/EIF4B/RPS14/RPL7/RPL5/RPL10A/RBM4/RPS3A/RPS10/RBM24
GOBP_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS 38 0.6177682 1.782298 0.0019790 0.0242523 0.0195690 2031 S100A7/TNFAIP6/SLIT2/CXCL8/CCL5/LBP/THBS1/IL23A/C5AR2/EDN1/CXCL17/RARRES2/IL34/CSF1/NOD2/MAPK3/MOSPD2
GOBP_REGULATION_OF_LIPID_METABOLIC_PROCESS 259 0.3890120 1.495425 0.0019969 0.0244072 0.0196939 1807 PLA2G3/APOC1/DHCR7/INSIG1/FGFR4/LPIN1/MLXIPL/STARD4/LDLR/TRIB3/FGF2/SNCA/DISP3/IL1B/SERPINA3/PTGS2/CNR1/CEACAM1/SCARB1/ELOVL5/NR4A3/MFSD2A/IL1A/TNF/BMP6/ACADL/LACTB/SOX9/PIK3IP1/IDH1/FGF1/BMP2/PDGFB/CCN1/RNF213/RUBCN/CHP1/AGAP2/RARRES2/ABCA7/LYN/NPC2/FLT1/IRS2/GFI1/LPCAT1/NOD2/SPHK1/DAB2/EEF1A2/PPARGC1A
GOBP_POSITIVE_REGULATION_OF_T_CELL_MIGRATION 22 0.7119548 1.835751 0.0020986 0.0254502 0.0205355 2105 S100A7/CXCL10/CCL20/CCL5/ADAM8/OXSR1/TNFSF14/ADAM17
GOBP_PROTEIN_KINASE_B_SIGNALING 152 0.4358229 1.568777 0.0020979 0.0254502 0.0205355 2830 NTRK1/NTRK3/FGF2/XDH/KDR/CCL5/IGF2/IL1B/THBS1/CAVIN3/CSF3/PEAR1/PLK3/GDF15/ADAM8/CX3CL1/TNF/MEIS3/HBEGF/SOX9/C1QTNF1/ENG/DDIT3/SH2B3/HLA-G/RRAS/PTPRJ/ADTRP/MET/EGF/TYRO3/CD40/SESN2/MST1R/TPBG/MYDGF/NTRK2/P2RX4/ILK/RASD2/TGFBR1/SRC/INPP5F/F3/NRG1/EPHA2/HYAL2/DAG1/MFHAS1/IL18/RTN4
GOBP_REGULATION_OF_PROTEIN_SECRETION 191 0.4194406 1.557821 0.0020933 0.0254502 0.0205355 2429 ACHE/CYP51A1/HMGCR/RSAD2/TTN/CCL5/ACSL4/IL1B/CCN3/CNR1/AACS/ADAM8/ANKRD1/IL1A/TNF/BMP6/NOS2/GPR68/PCK2/FOXA2/SAA1/FKBP1B/TLR2/KLF7/TGFB2/TLR4/LRRC8A/RHBDF2/ADAM9/GPR27/ADTRP/ANO1/STX4/ATP13A2/ADCY5/RAB11FIP1/CD200/LLGL2/IRS2/SLC8B1/C1QTNF3/SOX4/CFTR/EFNA5/ZBED6/ISL1/FAM3D/ENSA/F2RL1/GLUD1/DNAJC1/TRPM4/ABCA12/PFKFB2/STX1A/RAB11FIP5/ERP29/DOC2B/SLC12A2/FRMD4A/SERGEF
GOBP_INTERLEUKIN_6_PRODUCTION 110 0.4701540 1.632479 0.0021250 0.0256511 0.0206976 3125 EREG/KLF2/LBP/FOXP3/IL1B/IFIH1/ZC3H12A/C5AR2/ARID5A/MYD88/IL1A/CX3CL1/IL1RL2/TNF/TICAM1/NOS2/CD47/LGALS9/TNFAIP3/TLR2/TLR4/PTAFR/CLEC7A/IRAK3/SELENOS/IL36A/CD200/NOD2/C1QTNF3/AKIRIN2/BCL10/ISL1/PTPN22/F2RL1/SYK/HLA-B/SPON2/RIPK2/CAPN2/NOD1/TMEM106A/HYAL2/CEBPB/MAPKAPK2/TIRAP/PTPN11/SIRPA/TWIST1
GOBP_OSSIFICATION 322 0.3550264 1.395370 0.0021261 0.0256511 0.0206976 2264 ACHE/EBP/TNFAIP6/ISG15/FZD9/FASN/IFITM1/SLC8A1/SCX/FGF2/ALPL/MMP16/IGF2/SMOC1/COL13A1/BMP8B/PTGS2/LRRC17/DKK1/FOXC2/EGR2/SEMA7A/AREG/TNF/FAM20C/BMP6/MAPK11/SOX9/BMP2/COL6A1/FSTL3/TP53INP2/EIF2AK3/TGFB2/MEF2C/ADRB2/ATF4/CCN1/ENPP1/JUND/GREM1/PDLIM7/CSF1/TPM4/TUFT1/PPARGC1B/KL/COL1A1/ID4/CTNNBIP1/RRBP1/NOCT/PTHLH/KLF10/MMP13/BCAP29/PHEX/CCN4/ADAR/GABBR1/SBNO2/MAPK3/ID3/TRPM4/IARS1/HDAC7/MMP14/CTHRC1/ILK/SMAD6
GOBP_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS 34 0.6384570 1.812473 0.0021514 0.0258891 0.0208897 2172 ELOVL6/ACSL1/HSD17B12/SLC25A1/GGT7/ACSL4/ELOVL5/GGT5/AACS/ELOVL7/ACACA/ACSS3/ELOVL1/HACD2/ACSL5/FAR2/ELOVL4
GOBP_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS 111 0.4631159 1.611132 0.0021670 0.0260092 0.0209866 1807 PLA2G3/APOC1/MLXIPL/STARD4/LDLR/FGF2/DISP3/IL1B/PTGS2/SCARB1/ELOVL5/NR4A3/MFSD2A/IL1A/TNF/BMP6/FGF1/PDGFB/CCN1/CHP1/AGAP2/LYN/FLT1/IRS2/NOD2/DAB2/EEF1A2/PPARGC1A
GOBP_SKELETAL_SYSTEM_DEVELOPMENT 372 0.3609576 1.433915 0.0021811 0.0261111 0.0210688 2677 EBP/INSIG1/HYAL1/DLX2/SCX/SNORC/FGF2/HYAL3/HOXB1/KDR/ALPL/HOXA10/MMP16/HHIP/MATN3/COL13A1/BMP8B/CCN3/LRRC17/FST/EDN1/FOXC2/ARID5A/CYP26B1/ALX1/CDKN1C/FLVCR1/FAM20C/BMP6/GPR68/MAPK11/SOX9/ACVRL1/LOXL2/BMP2/HOXB5/ENG/EIF2AK3/SPNS2/CSRNP1/TGFB2/MEF2C/MTHFD1L/HAPLN3/CCN1/SH2B3/COL9A2/GREM1/ITGB8/VKORC1/TTC9/WNT7A/FLI1/PPARGC1B/COL1A1/HOXB6/CTC1/SOX4/MDFI/PTHLH/MAF/MMP13/PHEX/CCN4/PDGFC/SRF/ZEB1/MAPK3/SLC39A1/ITGB6/SERPINH1/TGFBI/MMP14/PIP4K2A/PBXIP1/PLS3/PKDCC/TGFBR1/SRC/HEXB/SH3PXD2B/MSX2/BMP3/HSD17B1/TLL1/EPHA2/HYAL2/ZNF219
GOBP_B_CELL_DIFFERENTIATION 93 0.4804024 1.620476 0.0021907 0.0261594 0.0211077 2594 NTRK1/FZD9/CLCF1/KLF6/VCAM1/HDAC9/IL4I1/TNFSF13B/CARD11/LGALS1/DOCK10/LRRC8A/PTPRJ/IL11/INHBA/DNAJB9/PTPN2/SYK/ADAM17/CEBPG/MMP14/BCL3/MALT1/GPS2/ST3GAL1/BAK1/CMTM7
GOBP_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS 262 0.3884004 1.496428 0.0022381 0.0266574 0.0215096 2218 PLA2G3/APOC1/DHCR7/INSIG1/FGFR4/SLC2A6/MLXIPL/STARD4/LDLR/TRIB3/PPP1R3G/SNCA/SLC7A11/PHLDA2/IGF2/IL1B/PTGS2/CNR1/CEACAM1/PMAIP1/ELOVL5/NR4A3/MFSD2A/TNF/BMP6/ACADL/NOS2/SOX9/FGF1/FOXA2/BMP2/C1QTNF1/PTAFR/CDA/ENPP1/PGP/SELENOS/MYC/IRS2/NLN/GFI1/ANTKMT/SLC7A7/DAB2/C1QTNF3/PPARGC1A/SESN2/DDIT4/HRH1/ANXA1/PTPN2/PFKFB2/ENTPD5/SLC27A4/GPT
GOBP_LIPID_HOMEOSTASIS 122 0.4618754 1.617223 0.0022627 0.0268813 0.0216902 906 PNPLA3/TMEM97/PCSK9/INSIG1/FGFR4/LIPC/LIPG/MLXIPL/LDLR/NPC1/DISP3/LCAT/HDAC9/ACOXL/SCARB1/ABHD4/ANGPTL4/TLCD1/SREBF2/EHD1/ACACA
GOBP_MEIOSIS_II_CELL_CYCLE_PROCESS 10 -0.8125776 -1.812781 0.0022732 0.0269376 0.0217357 363 SGO2/BUB1/SGO1/BUB1B
GOBP_HORMONE_BIOSYNTHETIC_PROCESS 45 0.5864124 1.746654 0.0023198 0.0274064 0.0221139 2708 DHCR7/HSD17B7/HSD17B12/SRD5A3/STC2/BMP6/BMP2/DUOX2/GFI1/HSD17B8/DAB2/TG/EGR1/HSD17B1/NFKB1/WNT4
GOBP_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 98 0.4855197 1.650765 0.0023303 0.0274064 0.0221139 3181 RSAD2/TNIP3/OAS1/LBP/IRF7/BIRC3/IRAK2/IFI35/MYD88/TNIP1/TNF/TICAM1/NFKBIA/RFTN1/LGALS9/LY96/TNFAIP3/TLR2/NMI/TLR4/TNIP2/IRAK3/TYRO3/LYN/GFI1/NOD2/PELI1/BCL10/CD40/IRAK1/PTPN22/F2RL1/RIPK2/GPS2/SMPDL3B/S100A14/IRF1/MFHAS1/RTN4/DAB2IP/MAPKAPK2/SLC15A4/TIRAP/MAPKAPK3/FLOT1/RPS6KA3/CAV1
GOBP_ENDOCYTOSIS 459 0.3433469 1.388456 0.0023263 0.0274064 0.0221139 3636 ARC/APOC1/ACHE/PCSK9/SGIP1/SLC2A4/LDLR/DPYSL2/SYT2/CXCL8/SYT1/NPC1/ITGAM/SNCA/NOSTRIN/LBP/LRP8/THBS1/CEACAM1/SCARB1/CD177/PEAR1/DKK1/SERPINE1/SCARF1/EPHA3/ANK2/TMPRSS5/AMN/CXCL16/VEGFA/COLEC10/EHD1/ELMO1/LOXL2/APOBR/C4BPA/MARCHF3/RAB5B/WASF1/ADRB2/SNX9/CLEC7A/ENPP1/LDLRAD3/PACSIN1/GREM1/RUBCN/CACNG8/MFGE8/XKR9/ABCA7/PDLIM7/EGF/TPCN2/ITGB3/HOOK2/EHD4/CD151/SPHK1/DAB2/RAB4B/MICALL1/TMPRSS13/OLR1/CSNK1G2/ADGRB1/HSPG2/RAB27B/RHOG/BICD1/MAPK3/F2RL1/XKR8/ITGAV/ARHGAP27/AP2B1/GULP1/SYK/CD9/STX1A/SPON2/SNX12/CAP1/SRC/ITSN1/SURF4/INPP5F/RINL/ITSN2/ARHGAP12/NECAP1/TFRC/ACTB/MARCHF2/ACTG1/PIK3C2A/CAV2/MYH9/C3/MAPKAPK2/OCIAD2/NEDD4/RNASEK/CLTB/SMPD1/SYNJ2/TGFBR2/MAPKAPK3/FLOT1/DNER/LGALS3BP/SH3KBP1/CAV1/ARFGAP1/DNAJC13/ABL2/ANKFY1/PPT1/SH3GL1/RIN3/WASL/RAB34/CTTN/NECAP2/BIN1/TNK2/CD63/PICALM/PACSIN2/SCARB2/CLCN5/HRAS/CYTH2/LRP10
GOBP_MACROAUTOPHAGY 291 0.3734198 1.444303 0.0023727 0.0278345 0.0224594 4649 NPC1/HSPB8/KDR/ADPRH/UCHL1/FEZ1/MAP1LC3B2/IKBKG/HDAC6/TP53INP2/ADRB2/GABARAPL1/RNF213/RUBCN/OPTN/ATP13A2/CHMP7/TMEM41B/WIPI1/NOD2/STBD1/SESN2/CHMP6/EPM2A/MAPK3/RNF31/VPS33B/VMP1/PIP4K2A/SQSTM1/GPSM1/HMOX1/RIPK2/MCOLN1/SRC/VPS37B/NOD1/PLAA/AUP1/ATG2A/VIPAS39/PIP4K2C/TBC1D25/TIGAR/RHEB/ERN1/GABARAP/NEDD4/MAP1LC3B/ATP6V1E2/DDRGK1/FEZ2/SH3GLB1/VCP/UBQLN4/CHMP1B/ATG13/PIP4K2B/CHMP4C/WDR45/RETREG3/TAFAZZIN/RAB43/PACS2/VPS37D/EI24/PHF23/SMURF1/ZFYVE1/ATP6V1B2/ULK3/ILRUN/RAB33B/HIF1A/VPS4A/CHMP2B/ATG14/VPS37A/USP36/ATP6V0B/EXOC8/TP53/UFM1/STX12/PIKFYVE/ATP6V0A1/SPTLC2/RAB7A/MVB12A/AKT1/ARL8B/RAB19/WDR81/PSEN1/SNF8/UBQLN1/MTMR14/SNX6/ATG101/CALCOCO2/QSOX1/ATP6V1H/ATG9A/HTT/GNAI3/RALB/CHMP1A/ATG7/RAB5A/CHMP3/NRBP2/AP4M1/PGAM5/PIK3CA
GOBP_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION 20 0.7212036 1.827514 0.0023825 0.0278739 0.0224912 3192 RSAD2/IL1B/ARID5A/CD55/IL18R1/TRAF2/MALT1/IL1R1/IL18/HLA-A/FZD5
GOBP_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE 107 -0.4537849 -1.653937 0.0023880 0.0278739 0.0224912 1590 RRM1/MEIS2/SASS6/CENPJ/MTBP/CDC7/STOX1/FBXO5/ANAPC4/CCNB1/CDC25C/CDC25A/CDT1/ESPL1/CDK1/SMOC2/CDCA5/DLGAP5/RRM2/DTL/UBE2C
GOBP_REGULATED_EXOCYTOSIS 172 0.4095559 1.506978 0.0024016 0.0279632 0.0225632 2252 PLA2G3/ADRA1A/SYT2/HYAL3/SYT1/ITGAM/SYNGR3/SNCA/LAT2/UNC13A/SYT17/CNR1/CEACAM1/CD177/NR4A3/CLTRN/ANXA3/STX3/STXBP1/ADGRE2/STX11/UNC13D/LGALS9/PPFIA3/PTAFR/CBARP/HLA-F/STX4/LYN/RAB11FIP1/WNT7A/GAB2/MICAL1/F2RL1/GIPC1/TRPV6/ABCA12/SYK/ARHGAP17/STX1A/RAB11FIP5/DOC2B/HMOX1
GOBP_LIPID_LOCALIZATION 338 0.3555691 1.403628 0.0024168 0.0280700 0.0226494 2427 PLA2G3/APOC1/PCSK9/LIPC/LIPG/SQLE/STARD4/LDLR/ANO4/ACSL1/PLA2G4C/NPC1/SLC5A8/DISP3/LBP/LCAT/IL1B/ATP8A2/THBS1/ZC3H12A/CEACAM1/SCARB1/YJEFN3/STRA6/EDN1/SLCO1B1/MFSD2A/IL1A/TNF/BMP6/NFKBIA/NOS2/SREBF2/EHD1/APOL1/IKBKE/STOML1/APOBR/SLC10A6/C1QTNF1/APOL2/SPNS2/ANO9/PTGES/ENPP1/RNF213/PLSCR1/APOL6/INHBA/XKR9/ABCA7/EGF/SIGMAR1/NPC2/TPCN2/ITGB3/TMEM41B/IRS2/NPC1L1/DAB2/ESYT1/CFTR/SLCO3A1/ANO7/ANXA1/PTPN2/XKR8/ITGAV/PRELID1/GULP1/ABCA12/SLC10A3/PITPNB/SYK/ACSL5/ATP11A/FURIN/P2RX4/VMP1/SLC27A4/PIP4K2A/ABCA3/ATP10A/HEXB/GPS2/SURF4/SLC27A5
GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS 38 0.6120432 1.765781 0.0024447 0.0282531 0.0227971 2425 IDO1/CCL5/HSH2D/IRF7/TSC22D3/PRKCQ/SELENOS/IRS2/ARG2/NOD2/BCL10/IL7R/PIP/ST3GAL1
GOBP_INTERFERON_GAMMA_PRODUCTION 77 0.5107054 1.668673 0.0024388 0.0282531 0.0227971 3323 EBI3/ISG15/FOXP3/IL1RL1/IL1B/ZC3H12A/IL23A/ARID5A/TNF/RIPK3/CD47/CD274/LGALS9/DDIT3/IL18R1/TLR4/CLEC7A/INHBA/CD276/BTN3A1/NOD2/ISL1/PTPN22/F2RL1/CEBPG/BCL3/RIPK2/SLC7A5/TYK2/IL1R1/IL18/FADD/HLA-A/SIRPA/FZD5/TRIM27/BTN3A2
GOBP_MONOCYTE_DIFFERENTIATION 29 0.6527612 1.798196 0.0024687 0.0283902 0.0229078 1778 MT1G/FASN/IRF7/IL31RA/VEGFA/GPR68/JUN/MYC/IL34/CSF1/IFI16/CTNNBIP1
GOBP_REGULATION_OF_HORMONE_LEVELS 352 0.3547027 1.404237 0.0024667 0.0283902 0.0229078 3119 PLA2G3/DHCR7/HSD17B7/LIF/RDH11/HSD17B12/CCL5/ACSL4/IL1B/SLCO4A1/CCN3/SRD5A3/CNR1/CYP46A1/EDN1/AACS/CLTRN/SLCO1B1/IL4I1/DUOXA2/STC2/CYP3A5/CYP26B1/IL1RN/RAB8B/TNF/BMP6/SDR16C5/NOS2/GPR68/PCK2/ERO1A/FOXA2/BMP2/BCO1/C1QTNF1/ALDH1A3/FKBP1B/KLF7/LIPE/ECE1/LRRC8A/RETSAT/IL11/INHBA/PAX8/GPR27/ANO1/CYP1B1/DUOX2/STX4/LYN/ADCY5/RAB11FIP1/IRS2/ACE2/GFI1/HSD17B8/SLC8B1/DAB2/C1QTNF3/DHRS7/SOX4/CFTR/DUOXA1/EFNA5/ZBED6/ISL1/CRYM/FAM3D/ENSA/GABBR1/ANXA1/GLUD1/NIBAN2/TRPM4/TRPV6/ABCA12/PFKFB2/FURIN/STX1A/RAB11FIP5/ALDH1A2/SLC5A5/GCNT4/DOC2B/TG/SLC7A5/EGR1/CYP2S1/DGAT1/RDH13/HSD17B1/CYP2C18/PLB1/NFKB1/WNT4/GLUL/SULT1B1/PNPLA2/CYP2C9/RDH10/PIM3/BRSK2/PTPN11/ICA1/CACNA1H/MCU/SLC39A14/CPT1A
GOBP_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY 170 0.4180710 1.537659 0.0024767 0.0284120 0.0229253 2469 THEMIS2/LAT2/FOXP3/CMTM3/ZC3H12A/CEACAM1/C5AR2/NR4A3/FYN/PLPP4/CARD11/GBP1/RFTN1/IKBKG/CD47/MICB/UBASH3A/MEF2C/CLEC7A/HLA-G/KLRD1/PLSCR1/PRKCQ/PTPRJ/DUSP3/CD276/LYN/NFKBIZ/BTN3A1/NFKBID/BCL10/CD40/PTPN22/PTPN2/RNF31/THY1/SYK/BCAR1/RIPK2/SRC/MALT1/PRKCH/GPS2/LPXN/RBCK1
GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION 222 0.3999774 1.517253 0.0024837 0.0284226 0.0229339 3406 CCL4/LDLR/IFITM1/IFIT1/CXCL6/CXCL8/NPC1/CCL5/IFI27/ZC3H12A/SCARB1/IFITM3/MYD88/LAMP3/CLDN9/TRIM31/LGALS1/CD55/JUN/APOL1/LGALS9/TRIM21/TRIM5/ICAM1/PLSCR1/TRIM14/PVR/SLC3A2/NECTIN4/CD46/TYRO3/TPCN2/CHMP7/ITGB3/TMEM41B/ACE2/THOC6/SLC52A2/CHMP6/ITGB7/TRIM25/F2RL1/KRT6A/ITGAV/ITGB6/IFITM2/SAP30BP/TREM1/TRIM22/SRC/STOM/VPS37B/TFRC/LY6E/CLDN1/CD86/EPHA2/NECTIN2/HYAL2/RAB9A/PPIA/DAG1/CAV2/POU2F3/P4HB/RNASEK/RRP1B/SMPD1/VPS18/ITGA5/ITGB5/CAV1/CFL1/CHMP1B/TRIM27/EXOC2/SLC1A5/CHMP4C/SLC52A1
GOBP_REGULATION_OF_VASCULATURE_DEVELOPMENT 218 0.3999367 1.515908 0.0024912 0.0284387 0.0229469 3061 CXCL10/HYAL1/CCR3/CXCL8/FGF2/KDR/KLF2/IL1B/ADM2/THBS1/ZC3H12A/CEACAM1/YJEFN3/FOXC2/ANGPTL4/SERPINE1/CD34/EMILIN2/IL1A/ANXA3/PML/TNF/RHOB/VEGFA/WARS1/STAT1/FGF1/ACVRL1/VASH2/TNFAIP3/ENG/TGFB2/HLA-G/RRAS/GREM1/KLF4/ADAMTS9/ITGB8/CYP1B1/FLT1/GADD45A/BMPER/CEMIP2/SPHK1/SP100/ETS1/AKT3/CD40/ADGRB1/ISL1/HSPG2/TJP1/NIBAN2/MYDGF/MAPK7/ADAMTS1/HMOX1/BTG1/SLC12A2/LRG1/F3/RAPGEF3/EPHA2/WNT4/GLUL/ECM1/C3/ID1/DAB2IP/HK2/SARS1/JUP/PLCG1/ITGA5/SPARC/TGFBR2/JAK1
GOBP_SPROUTING_ANGIOGENESIS 107 0.4749596 1.641439 0.0025411 0.0289374 0.0233493 2252 FGFBP1/DLL4/SLIT2/NR4A1/FGF2/KDR/KLF2/HDAC9/THBS1/PTGS2/CEACAM1/YJEFN3/FOXC2/VEGFA/FGF1/ACVRL1/LOXL2/ENG/RNF213/GREM1/KLF4/ADAMTS9/ADTRP/ESM1/BMPER/CEMIP2/AKT3/SRF/ANXA1/TJP1/CARD10/HDAC7/EPHB4/HMOX1
GOBP_NEGATIVE_REGULATION_OF_CHOLESTEROL_STORAGE 10 -0.8093837 -1.805656 0.0025548 0.0290227 0.0234181 297 CES1/NR1H3/TREM2/ABCA1/ABCG1
GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE 56 0.5592054 1.741046 0.0025655 0.0290739 0.0234594 3192 RSAD2/IL1B/NR4A3/CAMK4/ARID5A/SEMA7A/TICAM1/CD55/IL18R1/TLR4/CLEC7A/HLA-G/HLA-F/NOD2/BCL10/HLA-E/F2RL1/SPON2/TRAF2/MALT1/SLC7A5/LACC1/IL1R1/IL18/HLA-A/FZD5
GOBP_MEMBRANE_RAFT_ORGANIZATION 19 0.7196942 1.797153 0.0025871 0.0292470 0.0235991 3584 NPC1/YJEFN3/FA2H/RFTN1/ABCA7/S100A10/CAV2/MYADM/FLOT1/CAV1/EMP2/PPT1/PACSIN2
GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY 14 0.7779271 1.810520 0.0027293 0.0307799 0.0248360 2470 FOXP3/CEACAM1/IL4I1/HLA-G/KLRD1/HLA-F/NOD2/IL7R/AHR
GOBP_LEUKOCYTE_PROLIFERATION 224 0.3962407 1.505900 0.0027612 0.0310653 0.0250662 3060 EBI3/CD70/IDO1/TNFSF9/CCL5/CLCF1/IGF2/FOXP3/IL1B/BST2/VCAM1/IL23A/FYN/IL4I1/MYD88/TNFSF13B/IL1A/CX3CL1/TNFRSF13C/TNFRSF1B/RIPK3/TICAM1/CARD11/CD55/CD274/LGALS9/TNFAIP3/FKBP1B/MEF2C/TLR4/HLA-G/PRKCQ/CDKN1A/GREM1/MSN/CD276/IL34/CSF1/CD46/LYN/CADM1/IRS2/BTN3A1/ARG2/TNFSF14/CD151/MAPK8IP1/PELI1/CTPS1/CD40/IL7R/HLA-E/PTPN22/MAPK3/ANXA1/F2RL1/ELF4/PDE5A/PNP/SYK/RIPK2/SLC7A1/MALT1/TYK2/AHR/CCND3/TFRC/CD86/IL15/NCK1/CEBPB/IRF1/WNT4/SOS2/IL18/FADD/ZBTB7B/TIRAP/HLA-A/BTN2A2/TGFBR2
GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION 30 0.6478465 1.785041 0.0027755 0.0311508 0.0251353 1908 KLF2/FOXP3/ZC3H12A/C5AR2/CX3CL1/TNF/TNFAIP3/TLR4/IRAK3/SELENOS/CD200/C1QTNF3/PTPN22
GOBP_ISOPRENOID_METABOLIC_PROCESS 91 0.4869516 1.638078 0.0028169 0.0315398 0.0254492 1492 MVD/HMGCS1/LSS/FDPS/HMGCR/IDI1/FDFT1/MVK/RDH11/LRP8/SRD5A3/CYP3A5/CYP26B1/SDR16C5/BCO1/ALDH1A3/PLPP6/LIPE/RETSAT/RARRES2/CYP1B1/NPC2
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION 29 -0.6209820 -1.775601 0.0028431 0.0316811 0.0255632 3621 PBX1/CDK4/NPM1/MECP2/DYRK3/DBF4B/RRM1/CDC7/STOX1/FBXO5/CCNB1/ATAD5/CDC25C/CDC25A/CDK1/DTL
GOBP_SIGNAL_RELEASE 321 0.3668131 1.439774 0.0028385 0.0316811 0.0255632 2164 PLA2G3/ADRA1A/NR4A1/SYT2/LIF/SYT1/SNCA/CCL5/ACSL4/UNC13A/IL1B/KMO/CCN3/CHRNB4/SYT17/CNR1/EDN1/AACS/CLTRN/IL1RN/IL1A/RAB8B/TNF/BMP6/STX3/NOS2/GPR68/STXBP1/PCK2/STX11/FOXA2/C1QTNF1/FKBP1B/KLF7/PPFIA3/PTGES/MEF2C/LRRC8A/IL11/INHBA/PAX8/GPR27/ANO1/STX4/LYN/ADCY5/RAB11FIP1/WNT7A/IRS2/PORCN/SLC8B1/DAB2/C1QTNF3/SOX4/CFTR/EFNA5/ZBED6/ISL1/FAM3D/ENSA/GABBR1/ANXA1/F2RL1/GLUD1/GIPC1/NIBAN2/TRPM4/TRPV6/ABCA12/SYK/PFKFB2/STX1A/RAB11FIP5/P2RX4
GOBP_PROTEIN_LOCALIZATION_TO_CHROMATIN 31 -0.6143845 -1.798488 0.0028593 0.0317860 0.0256478 2301 RUVBL2/FAM47E/MRNIP/LRWD1/EZH2/PLK1/ESCO2/CDCA5/H1-5
GOBP_REGULATION_OF_PROGRAMMED_NECROTIC_CELL_DEATH 24 0.6764509 1.771915 0.0028999 0.0320841 0.0258883 3437 ZBP1/FZD9/BIRC3/RIPK3/PELI1/BOK/RBCK1/CASP6/FADD/CASP8/CAV1/ARHGEF2/CFLAR
GOBP_REGULATION_OF_RESPONSE_TO_WOUNDING 124 0.4501608 1.580317 0.0028994 0.0320841 0.0258883 2734 RTN4R/SERPINC1/FGF2/PLAU/THBS1/CEACAM1/EDN1/TNFRSF12A/FOXC2/SERPINE1/SERPINB2/CD34/SCARF1/OCLN/TNF/HBEGF/CLDN4/FOXA2/C1QTNF1/TNFAIP3/FKBP1B/PDGFB/CLEC7A/SH2B3/KLF4/FERMT1/ADTRP/VKORC1/DUOX2/PHLDB2/PRKG1/PLPP3/CCN4/ANXA1/F2RL1/SERPINF2/TFPI/CD9/SERPINE2/SLC12A2/FLNA/INPP5F/MAP2K1/F3/CLDN1/NDEL1/WNT4/ACTG1
GOBP_REGULATION_OF_GTPASE_ACTIVITY 304 0.3686144 1.437517 0.0029224 0.0322571 0.0260279 3880 NTRK1/RGS7/CCL22/CCL4/CCL20/RGS16/RTN4R/NTRK3/ADPRH/CCL5/TRAPPC6A/EPHA3/CX3CL1/CPEB2/RASGRP3/TBC1D3D/ARHGAP11B/FGD2/NEDD9/SNX9/DOCK10/ADAP2/RASA4B/SPRY1/PLXNA3/TIAM2/DVL2/MET/ASAP3/PRKG1/NGEF/CCL17/CD40/EFNA5/GMIP/RHOG/RGS10/S100A10/F2RL1/PLXNA1/ARHGAP27/THY1/TBC1D4/NTRK2/BCAR3/RAP1GAP/SLC27A4/PLXNA4/DOCK6/PBXIP1/GPSM1/MAP4K4/ADAP1/SYDE2/ARHGAP12/MAPRE2/RSU1/RAPGEF3/CCPG1/SYDE1/EPHA2/NDEL1/TBC1D25/TBC1D10A/ASAP2/WNT4/SOS2/CAV2/RASAL1/FGD6/RAP1GAP2/DAB2IP/ITGA6/RRP1B/STMN3/FLCN/GRHL3/RANGAP1/ARHGEF5/TBC1D22B/TBC1D10B/ARHGAP29/TBC1D17/IQGAP1/TBC1D1/BIN1/TGM2/ARL2/PICALM/CRK/HRAS/RGP1/FGD4/RASA2/RGS14/SGSM3/ARHGEF10/RAPGEF1/CHN1/GSK3B/PIP5K1A/MMUT/CORO1C/TBC1D20
GOBP_INDOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS 17 0.7405220 1.813103 0.0029993 0.0328725 0.0265245 1470 IDO1/IDO2/KYNU/KMO/IL4I1/TPH2/HAAO
GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION 84 0.5008464 1.666143 0.0029877 0.0328725 0.0265245 2005 PLA2G3/TNFAIP6/LIF/EVI2B/IRF7/IL23A/CEACAM1/LRRC17/FOS/PRXL2A/CAMK4/TNF/GPR68/FSTL3/TLR4/INHBA/TFE3/MYC/IL34/CSF1/LYN/TRIB1/PPARGC1B/CTNNBIP1/KLF10/PTPN2
GOBP_AXON_DEVELOPMENT 382 0.3423554 1.361973 0.0029979 0.0328725 0.0265245 2656 NTRK1/PAX6/NREP/TUBB3/SLIT2/DPYSL2/RTN4R/OLFM1/L1CAM/MAP2/ISLR2/DRAXIN/NTNG1/ATP8A2/SEMA3B/SCN1B/RELN/CHODL/CNR1/ACTBL2/SEMA3D/EDN1/FYN/EPHA10/EGR2/UCHL1/FEZ1/SCARF1/EPHA3/SEMA7A/MAP1B/FGF13/VEGFA/NRXN3/LAMA3/LAMC2/STXBP1/JUN/SLITRK5/HDAC6/VASH2/ARTN/FKBP1B/KLF7/PTPRO/ECE1/VCL/PRKCQ/KLF4/PLXNA3/TIAM2/FLRT2/NRCAM/FOXB1/WNT7A/NCAM2/KIF5C/DBN1/SLC9A6/EFNA5/ADGRB1/ISL1/SHTN1/RHOG/NTNG2/S100A6/SRF/PLXNA1/TRIO/NIBAN2/THY1/NTRK2/B4GALT5/EPHB4/PLXNA4/COBL/FLNA/CCK/NTN1/SEMA3A/INPP5F/MAP2K1/ROBO2/VASP/ACTB/SEMA3C/EPHA2/NDEL1
GOBP_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS 263 0.3839703 1.478389 0.0030126 0.0329409 0.0265797 3087 PCSK9/FADS1/SCX/HABP4/TNFRSF10A/IL1B/VCAM1/KIF26A/ZC3H12A/PTGS2/PMAIP1/CDKN2B/FOS/MFSD2A/MAP1LC3B2/MYD88/ANKRD1/DSC2/ATF3/BMP6/SREBF2/UCN2/SOX9/FOXA2/PIEZO1/ENG/EIF2AK3/TLR4/ATF4/CDA/GABARAPL1/CDKN1A/CBS/EIF2AK2/LYN/PIM1/TNFSF14/WIPI1/COL1A1/GADD45A/IFI16/MARS1/BCL10/RIPOR1/CD40/KLF10/SESN2/PHEX/UPP1/SRF/MAPK3/HMOX1/CASP5/FOSL1/FAS/RRAGC/SLC9A1/BAK1/CNN2/SLC39A4/IL15/NFKB1/IRF1/WNT4/DAG1/GLUL/FOXA3/GABARAP/TNFRSF10B/NDOR1/MAP3K5/FADD/MAP1LC3B/CASP8/BRSK2/DEPDC5/FLCN
GOBP_RESPONSE_TO_NUTRIENT 112 0.4605837 1.604550 0.0030664 0.0334515 0.0269917 2252 CXCL10/LIPG/SLC8A1/ACSL1/ALPL/ASCL1/KYNU/VCAM1/PTGS2/CNR1/CDKN2B/STC2/CYP26B1/MAP1B/IL1A/STAT1/FOXA2/MTHFR/FKBP1B/ASS1/CYP1B1/PIM1/KL/COL1A1/NOD2/PHEX/ENSA/ARSB/SRF/TRIM25/ALDH1A2/SLC27A4/HMOX1
GOBP_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS 36 0.6155064 1.761968 0.0030766 0.0334844 0.0270183 2981 FGFBP1/DLL4/FGF2/KDR/HDAC9/THBS1/PTGS2/FOXC2/VEGFA/KLF4/AKT3/ANXA1/CARD10/HDAC7/HMOX1/MAP3K3/PIK3C2A/SRPX2
GOBP_GLYCEROLIPID_CATABOLIC_PROCESS 49 0.5740603 1.734775 0.0031206 0.0338056 0.0272774 1186 PNPLA3/APOC1/LIPC/LIPG/LDLR/PLA2G4C/GPCPD1/SCARB1/ENPP6/LIPH/LIPE/GDPD3
GOBP_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY 258 0.3775577 1.451642 0.0031185 0.0338056 0.0272774 2298 APOC1/LPIN1/PLAUR/NR4A1/IFI6/SERPINC1/HMSD/SNCA/A2ML1/SERPINB12/PI3/SERPINB7/DHCR24/BST2/SERPINA3/HDAC9/THBS1/PTGS2/TFPI2/BIRC3/COL6A3/ANGPTL4/SERPINE1/SERPINB2/SFN/SERPINB8/CPEB2/CST1/LAMP3/TIMP2/TNF/VEGFA/MASTL/SERPINB4/SERPINB9/FKBP1B/TGFB2/SPRY1/KLF4/CHP1/CSTB/CPAMD8/TNFSF14/IFI16/MICAL1/ANXA8/RFFL/GMIP/BICD1/ANXA1/SERPINF2/WFDC3/TMEM225B/TFPI/SPOCK1/FURIN/SERPINH1/MAPK7/USP14/SLC27A4/RARRES1/GPSM1/SERPINE2
GOBP_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS 40 0.5819566 1.692739 0.0031424 0.0339625 0.0274040 715 PLA2G3/FADS2/ELOVL6/FADS1/SCD/TBXAS1/IL1B/PTGS2/ELOVL5/EDN1/ELOVL7
GOBP_ORGANOPHOSPHATE_CATABOLIC_PROCESS 136 0.4336511 1.540586 0.0032243 0.0346078 0.0279247 3210 APOC1/LIPC/LIPG/LDLR/ENTPD8/PLA2G4C/XDH/NUDT8/NT5E/PDE4C/GPCPD1/NUDT10/SCARB1/NUDT11/TYMP/ENPP6/IDH1/ENTPD2/PLPP6/GDPD3/ENPP1/NUDT17/PLA2G15/UPP1/ACOT7/PDE5A/PNP/PDE9A/ENTPD5/NUDT16/INPP5F/ENTPD6/SMPDL3B/PDE8A/PLB1/NT5C2/GDA/CNP/PLA2G4A/PLCG1/SMPD1/SYNJ2/VCP/PLBD2/FITM2
GOBP_TEMPERATURE_HOMEOSTASIS 136 0.4326608 1.537068 0.0032243 0.0346078 0.0279247 2841 ACHE/ELOVL6/LPIN1/SCD/ACSL1/ALPL/IL1B/PTGS2/CNR1/ADAMTS5/FOXC2/IL1A/TNF/VEGFA/ACADL/PRLR/DDIT3/IL18R1/PTGES/ADRB2/TLR4/ATF4/ADIPOR2/MFAP2/GRB10/TFE3/PLCL1/PPARGC1B/LCN2/PPARGC1A/PDGFC/SYK/ADAM17/SQSTM1/IL4R/EGR1/ACADVL/IL15/NOVA1/CEBPB/IL18/RHEB/ID1
GOBP_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION 440 0.3428628 1.377389 0.0032147 0.0346078 0.0279247 4023 ACHE/CYP51A1/HMGCR/INSIG1/RSAD2/TTN/BBC3/ITGAM/SLC7A11/CCL5/ACSL4/IL1B/IFI27/CCN3/DERL3/ZC3H12A/PTGS2/CNR1/PLK3/FYN/AACS/ADAM8/SFN/ANKRD1/IL1A/TNF/BMP6/NOS2/GPR68/SREBF2/PCK2/HDAC6/FOXA2/SAA1/SH3TC2/FKBP1B/TLR2/KLF7/TGFB2/TLR4/PTP4A3/LRRC8A/CHP1/FERMT1/RHBDF2/ADAM9/GPR27/LCP1/ADTRP/ANO1/STX4/MTCL1/ATP13A2/ADCY5/RAB11FIP1/ABLIM3/CD200/LLGL2/IRS2/SLC8B1/SP100/C1QTNF3/SOX4/CFTR/MYO1C/RIPOR1/EFNA5/ZBED6/ISL1/FAM3D/ENSA/EDEM1/B3GAT3/F2RL1/GLUD1/DNAJC1/RNF31/TRPM4/MICALL2/ABCA12/PFKFB2/STX1A/RAB11FIP5/ERP29/DOC2B/PKDCC/SLC12A2/FLNA/SNX12/SRC/STOM/FRMD4A/SERGEF/MIEF2/RAPGEF3/HYAL2/NDEL1/PAM/PPIA/GLUL/RHBDD3/CDH1/PIM3/JUP/BRSK2/PTPN11/RHBDF1/ICA1/SIRT7/MCU/CPT1A/SH3GLB1/FZD5/ZPR1/RANGAP1/ARHGEF5/ATG13/STXBP5/EDEM2/P3H1/MIEF1/NUP58/OS9/TMEM30A/ABAT/IRS1/CAPN10/HRAS/ALOX5/UBE2J1/BMP4/NMT1/PRNP/KCNN4/MIDN/SEC24A/IL12A/RAC2/GSK3B/SMAD3/LLGL1/HIF1A/PPARD/PTPN1/LEPROT/SYT7/USP36/VEGFC/DISP1/UFM1/DERL2/RAB8A
GOBP_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION 492 0.3300427 1.343228 0.0032984 0.0353214 0.0285005 2494 TNFAIP6/CXCL10/INSIG1/PAX6/FGL2/PRTG/LDLR/TRIB3/DLX2/RTN4R/NTRK3/HOPX/XDH/MAP2/ASCL1/EREG/DISP3/IGF2/DRAXIN/FOXP3/IL1B/SEMA3B/CCN3/ZC3H12A/CEACAM1/LRRC17/FST/CDKN2B/SEMA3D/DKK1/CEACAM5/SEMA7A/IL1A/SOCS1/FGF13/AREG/SPRY4/G6PD/TNF/VEGFA/LAG3/STAT1/NFKBIA/GPR68/SOX9/GBP1/ACVRL1/SPDEF/FOXA2/DAAM2/BMP2/FSTL3/DDIT3/PDGFB/MELTF/TGFB2/TLR4/TGFB1I1/ENPP1/HLA-G/SPRY1/GREM1/PLXNA3/INHBA/DUSP10/MYC/LYN/TRIB1/ITGB3/WNT7A/TRIB2/CCL17/PRDM6/ID4/TMEM176A/NOCT/PTHLH/MARK1/JDP2/EFNA5/ZBED6/ISL1/CCN4/GPR37L1/ZEB1/ANXA1/PTPN2/TRIO/ID3/ITGAV/NFATC4/TRPM4/THY1/HDAC7/RAP1GAP/SPAG9/TMEM176B/SMAD6/KRAS/TGFBR1/NTN1/SEMA3A/GPS2/IL4R/TACSTD2/MSX2/IL17RD
GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION 205 0.3959600 1.484692 0.0033332 0.0356125 0.0287353 2718 IDO1/OAS3/OAS1/IL1R2/KLF2/LBP/FOXP3/IL1RL1/BST2/HDAC9/THBS1/ZC3H12A/IL23A/CEACAM1/C5AR2/RELB/CD83/CD34/CX3CL1/PML/TNF/LAG3/GBP1/CD274/LGALS9/HOMER3/TNFAIP3/ERRFI1/NMI/DDIT3/TGFB2/TLR4/HLA-F/KLF4/INHBA/IRAK3/SELENOS/CD200/TRIB2/ARG2/NOD2/C1QTNF3/N4BP1/DHX58/PTPN22/CDH3/ANXA1/F2RL1/HDAC7/FURIN/HMOX1/BCL3/TMSB4X/NPLOC4/ZFP36/AKAP8/EPHA2/NFKB1/RPS6KA4
GOBP_REGULATORY_T_CELL_DIFFERENTIATION 24 0.6722603 1.760938 0.0033638 0.0357768 0.0288680 1920 FOXP3/IL4I1/SOCS1/LAG3/FANCA/LGALS9/HLA-G/DUSP10/CD46/TOX
GOBP_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION 52 0.5528158 1.697731 0.0033639 0.0357768 0.0288680 3006 FGFBP1/FGF2/MIR200A/KDR/HDAC9/THBS1/PTGS2/FOXC2/VEGFA/PDGFB/ETS1/AKT3/CD40/ANXA1/ADAM17/HDAC7/P2RX4/HMOX1/TMSB4X/STAT5A/MAP3K3/MAP2K3/PIK3C2A/SRPX2/PLCG1
GOBP_RESPONSE_TO_NICOTINE 34 0.6289518 1.785489 0.0033999 0.0359160 0.0289803 790 NTRK1/SLC7A11/VCAM1/CHRNB4/CNR1/EDN1/TNF
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION 187 0.4135987 1.533941 0.0033954 0.0359160 0.0289803 3215 EBI3/CD70/TNFSF9/CCL5/IGF2/FOXP3/IL1B/VCAM1/IL23A/NR4A3/FYN/IL4I1/ADAM8/CD83/TNFSF13B/IL1A/SOCS1/IL1RL2/TNFRSF13C/TNF/CARD11/LGALS1/CD55/VNN1/CD47/CD274/LGALS9/PTAFR/HLA-G/PRKCQ/DUSP10/CD276/CD46/LYN/NFKBIZ/HLA-DOB/TNFSF14/NFKBID/SELP/NOD2/ETS1/SOX4/BCL10/IL7R/HLA-E/IRAK1/MAP3K8/PTPN22/ANXA1/THY1/PNP/SYK/RIPK2/SLC7A1/SRC/MALT1/IL4R/TYK2/TFRC/CD86/IL15/NCK1/IL18/FADD/ZBTB7B/HLA-A/BTN2A2/PTPN11/TGFBR2/SIRPA/HLA-DMA/CAV1/CHST2/RUNX3
GOBP_ORGANIC_ANION_TRANSPORT 248 0.3740808 1.430666 0.0034001 0.0359160 0.0289803 2427 PLA2G3/SLC26A9/SLC2A6/SNCA/SLC39A8/SLC7A11/SLC25A1/SLCO4C1/SLC26A4/SLC5A8/SLC7A9/SLC16A13/IL1B/KMO/SLCO4A1/SLC6A11/SLC2A3/CEACAM1/SLC26A6/EDN1/CLTRN/SLCO1B1/MFSD2A/SLC16A4/IL1A/SLC6A14/TNF/SLC13A5/NOS2/STXBP1/GRM1/CD47/SLC16A3/SLC10A6/SLC25A23/PTGES/LRRC8A/SLC25A25/SLC4A3/MPC1/SLC3A2/PRAF2/MYC/ACE2/SLC52A2/SLC52A3/SLC7A7/CFTR/SLC25A21/SLCO3A1/SLC1A4/GABBR1/ANXA1/GIPC1/SLC10A3/SYK/NTRK2/P2RX4/SLC27A4/SLC5A12/SLC7A1/SLC12A2/MGST1/LRRC8C/SLC7A5/SLC5A6/CYB5R1/SLC27A5
GOBP_CELLULAR_RESPONSE_TO_VIRUS 66 0.5352818 1.723574 0.0034386 0.0361591 0.0291764 1988 CXCL10/OAS3/OASL/IFI6/OAS1/CCL5/IRF7/IFIH1/ZC3H12A/BIRC3/MAPK11/LGALS9/IKBKE/DDX60/MMP12/DHX58/ADAR/TRIM25
GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY 114 0.4596136 1.607030 0.0034347 0.0361591 0.0291764 1592 ARC/PCSK9/NCF1/MAPK8IP2/EREG/PHLDA2/RELN/PLAU/EDN1/DKK1/PPP2R5B/SERPINE1/AREG/TNF/HBEGF/LYNX1/HDAC6/ERRFI1/GPRC5A/MEF2C/ADRB2/GREM1/CACNG8/EGF/ACE2/LDOC1
GOBP_LYMPHOCYTE_APOPTOTIC_PROCESS 57 0.5455006 1.700532 0.0034640 0.0363446 0.0293261 4124 IDO1/CCL5/HSH2D/TSC22D3/ADAM8/RIPK3/CD274/LGALS9/PRKCQ/LYN/IRS2/ARG2/BCL10/IL7R/PRELID1/PIP/ST3GAL1/FAS/BAK1/FADD/FNIP1/BMP4/TRAF3IP2/HIF1A/RAG1/TP53/RIPK1/AKT1
GOBP_TOLERANCE_INDUCTION 18 0.7150158 1.770611 0.0034908 0.0365436 0.0294867 2242 IDO1/FOXP3/CD274/LGALS9/TNFAIP3/HLA-G/IRAK3/LYN/HLA-E/XKR8/HLA-B
GOBP_REGULATION_OF_MAP_KINASE_ACTIVITY 157 0.4273157 1.549197 0.0035065 0.0366258 0.0295530 2445 HMGCR/TRIB3/S100A12/NTRK3/FGF2/IL1B/THBS1/EDN1/DKK1/UCHL1/ADAM8/SPRY4/TNF/VEGFA/FGF1/BMP2/FGD2/PDGFB/TLR4/SH2B3/PTPRJ/SPRY1/DUSP10/ADAM9/DVL2/IRAK3/IL34/EGF/LYN/TRIB1/FLT1/TRIB2/MAPK8IP1/NOD2/CD40/IRAK1/PTPN22/DUSP1/MST1R/PDGFC/PDE5A/SYK/DUSP16/ERP29/MAP3K10/TRAF2/SRC/TGFA
GOBP_FEMALE_MEIOTIC_NUCLEAR_DIVISION 27 -0.6445368 -1.800840 0.0035209 0.0366617 0.0295820 1152 HSF2BP/FMN2/SYCP2/FBXO5/AURKA/TRIP13/TTK/NDC80/PLK1/CCNB2/NCAPH/TOP2A
GOBP_REGULATION_OF_T_CELL_MIGRATION 32 0.6292288 1.750999 0.0035256 0.0366617 0.0295820 1633 S100A7/CXCL10/CCL20/CCL5/ADAM8/RIPK3/OXSR1/CD200/TNFSF14
GOBP_T_CELL_RECEPTOR_SIGNALING_PATHWAY 99 0.4579285 1.554176 0.0035791 0.0371347 0.0299636 3674 THEMIS2/FOXP3/ZC3H12A/CEACAM1/FYN/CARD11/GBP1/RFTN1/IKBKG/UBASH3A/PTPRJ/DUSP3/CD276/NFKBIZ/BTN3A1/NFKBID/BCL10/PTPN22/PTPN2/RNF31/THY1/BCAR1/RIPK2/MALT1/RBCK1/NECTIN2/PLCG1/HLA-A/BTN2A2/BTN3A3/BTN3A2/RELA/HRAS/PRNP/KCNN4
GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION 270 0.3696986 1.423231 0.0035921 0.0371879 0.0300065 2245 ACHE/CYP51A1/HMGCR/RSAD2/TTN/CCL5/ACSL4/IL1B/CCN3/CNR1/AACS/CLTRN/ADAM8/ANKRD1/LTBP2/IL1RN/IL1A/RAB8B/TNF/BMP6/NOS2/GPR68/PCK2/CTAGE4/FOXA2/SAA1/FKBP1B/TLR2/KLF7/TGFB2/TLR4/LRRC8A/RHBDF2/ADAM9/GPR27/ADTRP/ANO1/STX4/ATP13A2/ADCY5/RAB11FIP1/CD200/LLGL2/IRS2/BLOC1S3/PORCN/SLC8B1/C1QTNF3/SOX4/CFTR/LTBP1/EFNA5/ZBED6/ISL1/FAM3D/ENSA/SCG2/ANXA1/F2RL1/GLUD1/DNAJC1/CAVIN1/TRPM4/ABCA12/PFKFB2/STX1A/RAB11FIP5/ERP29/DOC2B
GOBP_RECEPTOR_MEDIATED_ENDOCYTOSIS 196 0.3990776 1.484643 0.0036281 0.0374767 0.0302395 2106 ARC/APOC1/ACHE/PCSK9/SGIP1/LDLR/CXCL8/ITGAM/SNCA/CEACAM1/DKK1/SERPINE1/SCARF1/AMN/CXCL16/VEGFA/WASF1/ADRB2/SNX9/LDLRAD3/GREM1/CACNG8/PDLIM7/EGF/TPCN2/ITGB3/DAB2/MICALL1/HSPG2/BICD1/ITGAV/ARHGAP27/AP2B1/SYK/CD9
GOBP_RESPONSE_TO_LECTIN 15 0.7606176 1.805692 0.0037360 0.0384218 0.0310022 2361 FYN/CLEC7A/KLRD1/MYC/LYN/SYK/SRC
GOBP_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION 53 0.5506392 1.698713 0.0037295 0.0384218 0.0310022 2297 ISG15/OAS3/OAS1/OAS2/IRF7/IFIH1/MYD88/TICAM1/STAT1/TLR2/TLR4/MMP12/DHX58/IRAK1/PTPN22/SYK/POLR3D/POLR3B/RIPK2
GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY 443 0.3357231 1.351969 0.0038140 0.0391375 0.0315796 2024 DEFB4A/CXCL10/CXCL11/ADRA1A/RGS7/RASD1/CCL22/CCL4/FZD9/CXCL9/PHF24/CCL20/CCR3/RGS16/CXCL8/OXER1/SNCA/EREG/CCL5/LPAR5/CNGB1/DEFB1/OR2I1P/CGB7/CXCL1/ADM2/GRK5/CNR1/MRGPRX3/C5AR2/GNG2/RNF157/EDN1/DGKI/GALR2/ADGRG2/CX3CL1/TAS2R3/AREG/RGS9/RGS20/GPR68/ADGRD1/UCN2/ADGRE2/GRM1/CELSR3/OR5P3/GNAZ/ENTPD2/HOMER3/GPRC5A/SPNS2/ADRB2/PTAFR/ECE1/PAX8/GPR27/ADGRF4/ANO1/MET/GNA15/ADCY4/OPN3/TYRO3/AKAP12/SIGMAR1/ADCY5/GNA12/NLN/TPRA1/LPAR2/GPR85/ITPR3/CCL17/SPHK1/GPR157/HCAR3/PTHLH/ADGRB1/HTR4/TMOD2/RGS10/GABBR1/HRH1/GPR37L1/BICD1/ANXA1/GPR63/F2RL1/GIPC1
GOBP_NEGATIVE_REGULATION_OF_PROTEIN_BINDING 80 0.4946292 1.636662 0.0038539 0.0394605 0.0318403 2049 PCSK9/TEX14/IFIT2/NES/IFIT1/MAP2/DKK1/PDGFB/ADRB2/CDKN1A/DDX11/DAB2/CTNNBIP1/MAPK3/NFATC4
GOBP_NEGATIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS 45 0.5712801 1.701582 0.0038689 0.0395269 0.0318938 1724 APOC1/INSIG1/LPIN1/TRIB3/CEACAM1/ACADL/BMP2/PDGFB/GFI1/LPCAT1/SPHK1
GOBP_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC 48 0.5709614 1.717593 0.0039037 0.0397959 0.0321109 1313 NTRK1/SYT1/MAPK8IP2/UNC13A/KMO/RELN/PTGS2/CNR1/DKK1/DGKI/TNF/STXBP1/GRM1/MEF2C/CACNG8
GOBP_MICROTUBULE_ORGANIZING_CENTER_LOCALIZATION 31 -0.6060729 -1.774158 0.0039183 0.0398573 0.0321605 2141 AKAP9/FHOD1/CEP83/AURKA/MAD2L1/DLGAP5/ASPM
GOBP_MUSCLE_STRUCTURE_DEVELOPMENT 471 0.3309346 1.340435 0.0039472 0.0400645 0.0323277 2810 CXCL10/ADRA1A/CXCL9/DLL4/SLC8A1/NR4A1/SMTN/TTN/SCX/HOPX/LIF/EREG/MAFF/PDLIM3/IGF2/CCN3/HDAC9/CHODL/GPCPD1/ADAMTS5/STRA6/RCAN1/TMOD4/EDN1/DKK1/FOXC2/CEACAM5/EGR2/COL6A3/FOS/GDF15/UCHL1/CYP26B1/ANKRD1/ANK2/ATF3/POPDC3/G6PD/ASB2/TNF/VEGFA/CFL2/DYSF/IGSF8/LGALS1/HBEGF/SVIL/MAPK11/SOX9/EHD1/BMP2/PIEZO1/PLEKHO1/ENG/DDIT3/PDGFB/ITGB1BP2/TGFB2/MEF2C/ASS1/MYL9/LRRC8A/PAX7/GREM1/IFRD1/LMNA/PDLIM7/FLII/SGCE/NLN/TNFSF14/PDLIM2/CCL17/PRDM6/CSRP1/TAGLN/ZBED6/ADGRB1/ISL1/TMOD2/VAMP5/SRF/ZEB1/ID3/XKR8/NFATC4/POPDC2/NIBAN2/CD9/TPM1/ATP11A/MMP14/SPAG9/CTH/BTG1/CAPN2/KRAS/TGFBR1/MAMSTR/IL4R/IGFBP3/EGR1/NRG1/SLC9A1/PDLIM5/LY6E/FOXN2/WNT4/ACTG1/DAG1/MYL6/CAV2/IL18/MYH9
GOBP_HEMOSTASIS 172 0.4040895 1.486864 0.0039802 0.0403110 0.0325265 2735 PLAUR/SERPINC1/SLC7A11/NFE2/PLAU/THBS1/CEACAM1/TFPI2/PROCR/PEAR1/EDN1/PF4V1/SERPINE1/VWF/SERPINB2/CD34/DGKI/EMILIN2/STXBP1/FOXA2/ENTPD2/RAP2B/SAA1/C1QTNF1/PDGFB/TLR4/VCL/MYL9/SH2B3/PLSCR1/PRKCQ/ADTRP/VKORC1/TYRO3/LYN/PRKG1/ITGB3/FLI1/GNA12/BLOC1S3/SELP/ITPK1/CSRP1/CD40/ANXA8/MYL12A/SRF/F2RL1/SERPINF2/TFPI/SYK/CD9/ILK/SERPINE2/FLNA/SRC/PAFAH2/RAB27A/F3/ACTB/ACTG1/PPIA
GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS 59 0.5383297 1.683217 0.0040116 0.0404542 0.0326421 3409 TRIB3/BBC3/CHAC1/PMAIP1/PML/ERO1A/EIF2AK3/DDIT3/ATF4/SELENOS/BOK/PTPN2/ERP29/TRAF2/HYOU1/BAK1/NCK1/CEBPB/ERN1/DAB2IP/TNFRSF10B/MAP3K5/BRSK2/SYVN1/HERPUD1
GOBP_POSITIVE_REGULATION_OF_HORMONE_SECRETION 82 0.4940855 1.638974 0.0040064 0.0404542 0.0326421 2245 PLA2G3/ACSL4/EDN1/AACS/RAB8B/BMP6/GPR68/PCK2/C1QTNF1/LRRC8A/INHBA/GPR27/ANO1/STX4/IRS2/DAB2/C1QTNF3/SOX4/CFTR/ISL1/GABBR1/GLUD1/TRPM4/PFKFB2/DOC2B
GOBP_ENDOTHELIAL_CELL_PROLIFERATION 125 0.4427950 1.553247 0.0040256 0.0405073 0.0326850 2814 FGFBP1/DLL4/CCR3/NR4A1/FGF2/XDH/KDR/IGF2/THBS1/SCARB1/CD34/TNF/BMP6/VEGFA/STAT1/JUN/ACVRL1/LOXL2/VASH2/BMP2/PDGFB/MEF2C/ATOH8/EGF/FLT1/ITGB3/BMPER/AKT3/FUT2/SCG2/MYDGF/ADAM17/MMP14/ALDH1A2/HMOX1/TGFBR1/STAT5A/NRAS/LRG1/F3/EPHA2/CAV2/ECM1/ERN1
GOBP_ALPHA_BETA_T_CELL_ACTIVATION 108 0.4511977 1.564179 0.0040591 0.0407565 0.0328860 3060 EBI3/RSAD2/FOXP3/ZC3H12A/IL23A/RELB/CD83/SOCS1/CD55/BATF/CD274/LGALS9/PRDM1/IL18R1/PRKCQ/NFKBIZ/ARG2/NFKBID/MAPK8IP1/HLA-E/PTPN22/TOX/ANXA1/ELF4/PNP/SYK/BCL3/RIPK2/MALT1/IL4R/TYK2/CD86/IL15/IRF1/IL18/ZBTB7B/HLA-A/TGFBR2
GOBP_CONNECTIVE_TISSUE_DEVELOPMENT 196 0.3969216 1.476622 0.0042085 0.0421668 0.0340239 3953 HYAL1/DLX2/SCX/SNORC/FGF2/HYAL3/SERPINB7/MATN3/BMP8B/CCN3/NAMPT/EDN1/FOXC2/ARID5A/CD34/BMP6/SOX9/ACVRL1/LOXL2/BMP2/KLF7/EIF2AK3/PDGFB/MEF2C/CCN1/SLC25A25/GREM1/ITGB8/CSF1/WNT7A/COL1A1/ID4/PPARGC1A/PTHLH/MAF/MMP13/CCN4/SRF/ZEB1/MAPK3/TRPM4/SERPINH1/TGFBI/PBXIP1/PKDCC/TGFBR1/SH3PXD2B/MSX2/EGR1/BMP3/SLC39A13/HYAL2/ZNF219/ECM1/PGRMC2/RUNX2/PTPN11/TGFBR2/DDRGK1/SLC39A14/ACTA2/FOXD1/RUNX3/EXT1/CFLAR/BMP4/HMGA2/BMPR2/MEX3C/BMP1/TIMP1/CSGALNACT1/SMAD3/HIF1A/PPARD/ARRDC3/TSKU/MEF2D
GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION 73 0.5017162 1.630775 0.0042244 0.0422353 0.0340793 3215 RSAD2/FOXP3/ZC3H12A/IL23A/RELB/CD83/SOCS1/CD55/BATF/CD274/LGALS9/IL18R1/PRKCQ/NFKBIZ/ARG2/NFKBID/TOX/ANXA1/BCL3/RIPK2/MALT1/IL4R/CD86/IL18/ZBTB7B/TGFBR2/RUNX3
GOBP_CELL_SUBSTRATE_ADHESION 302 0.3609446 1.407428 0.0043426 0.0433241 0.0349578 3890 L1CAM/ITGAM/KDR/HSD17B12/NTNG1/COL13A1/ITGA9/VCAM1/PLAU/THBS1/OLFM4/SERPINE1/VWF/ITGA10/CD34/EPHA3/CX3CL1/SPRY4/CEACAM6/VEGFA/TIMM10B/GBP1/UNC13D/ACVRL1/LAMB3/NEDD9/PDGFB/PTPRO/MELTF/CCN1/VCL/RRAS/DAPK3/PTPRJ/GREM1/ADAMTS9/TRIOBP/FERMT1/ITGB8/VIT/ADAM9/DUSP3/CSF1/RAC3/CDKN2A/TYRO3/PHLDB2/ITGB3/MMP12/COL5A3/SGCE/PTPRK/COL1A1/ACER2/DAB2/EFNA5/S100A10/ITGB7/NTNG2/SRF/ITGAV/DLC1/MICALL2/THY1/SPOCK1/ITGB6/MMP14/ILK/COL16A1/LAMC1/SMAD6/MAP4K4/COL17A1/FLNA/ITGA3/SRC/RHOD/LPXN/ATRNL1/TACSTD2/SLC9A1/ARPC2/RSU1/WNT4/ACTG1/DAG1/EPDR1/DOCK5/ID1/P4HB/ITGB4/NTN4/ITGA6/NID2/MYADM/JUP/ITGA5/ITGB5/GFUS/PDPN/TESK1/EMP2/HAS2/PLEKHA2/CTTN/AGR2/ARL2/WASHC2C/CD63/MACF1/CRK/ITGAL/RHOA/RELL2/RAC1/SDC4/RAC2/GSK3B/PIP5K1A/SMAD3/CORO1C/PPARD/ACTN1
GOBP_EPITHELIAL_CELL_PROLIFERATION 329 0.3529265 1.391437 0.0043555 0.0433601 0.0349868 2876 HYAL1/PAX6/FGFBP1/DLL4/CCR3/NR4A1/FGF2/XDH/KDR/EREG/IGF2/CCN3/THBS1/CEACAM1/SCARB1/C5AR2/FST/CDKN2B/NR4A3/CDKN1C/CD34/SFN/AREG/TNF/BMP6/VEGFA/SDR16C5/STAT1/SOX9/JUN/FGF1/ACVRL1/LOXL2/VASH2/BMP2/TNFAIP3/ERRFI1/PDGFB/TGFB2/MEF2C/FERMT1/DUSP10/ATOH8/MYC/EGF/FLT1/ITGB3/WNT7A/MMP12/PTPRK/BMPER/NOD2/DAB2/AKT3/FUT2/ISL1/SCG2/SGPP2/COL8A2/CDH3/MYDGF/ADAM17/MMP14/ALDH1A2/RAP1GAP/HMOX1/TINF2/LAMC1/TGFBR1/STAT5A/TGFA/NRAS/TACSTD2/MAP2K1/LRG1/F3/ZFP36/CLDN1/EPHA2/C6orf89/CEBPB/GLUL/CAV2/ECM1/ERN1/RTN4/ID1/DAB2IP/EAF2/FAP
GOBP_TYPE_I_INTERFERON_PRODUCTION 82 0.4904537 1.626926 0.0044480 0.0441868 0.0356539 3160 ISG15/OAS3/OAS1/OAS2/IRF7/IFIH1/RELB/MYD88/TICAM1/STAT1/TLR2/NMI/TRIM21/TLR4/MMP12/DHX58/IRAK1/PTPN22/SYK/POLR3D/POLR3B/RIPK2/NPLOC4/IRF1/TIRAP/PTPN11/SIRPA/FLOT1
GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS 28 0.6494222 1.771055 0.0045476 0.0450055 0.0363145 2425 IDO1/CCL5/HSH2D/TSC22D3/PRKCQ/IRS2/ARG2/BCL10/IL7R/PIP/ST3GAL1
GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY 157 0.4214115 1.527792 0.0045497 0.0450055 0.0363145 3181 NREP/THBS1/PEG10/CDKN2B/FOS/GDF15/CDKN1C/LTBP2/PML/JUN/ACVRL1/BMP2/ZEB2/SMAD9/PMEPA1/ENG/TGFB2/TGFB1I1/SPRY1/FERMT1/ITGB8/ADAM9/PTPRK/FMOD/DAB2/LTBP1/VEPH1/ZEB1/GIPC1/ADAM17/FURIN/ITGB6/SMAD6/ITGA3/TGFBR1/SRC/LPXN/IL17RD/LRG1/VASN/CAV2/ID1/LATS2/SPRED2/ZMIZ2/TGFBR2/ITGB5/FLCN/CAV1
GOBP_OUTER_DYNEIN_ARM_ASSEMBLY 19 -0.6935882 -1.804013 0.0045677 0.0450880 0.0363810 3340 DNAAF5/ZMYND10/ODAD4/DNAAF11/DNAAF4/DNAL1/ODAD1/ODAD3/DAW1/DNAI1/LRRC49/DNAI2/DNAAF8/DNAH5/ODAD2/DNAAF6/DNAAF1
GOBP_T_CELL_APOPTOTIC_PROCESS 39 0.6014484 1.740141 0.0045793 0.0451068 0.0363962 4124 IDO1/CCL5/TSC22D3/ADAM8/RIPK3/CD274/LGALS9/PRKCQ/ARG2/BCL10/IL7R/PRELID1/PIP/ST3GAL1/FAS/BAK1/FADD/BMP4/HIF1A/RAG1/TP53/RIPK1/AKT1
GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 45 0.5671351 1.689236 0.0045963 0.0451796 0.0364550 1400 PAX6/FGF2/LIF/CDKN2B/SERPINE1/SFN/BMP6/SOX9/ACVRL1/ZBED2/TRIM16/PAX8/ATOH8
GOBP_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR 44 0.5685979 1.683640 0.0046377 0.0454909 0.0367061 3437 ASCL1/SOX9/ERRFI1/DUSP3/MYC/COL1A1/DAB2/PTPN12/MARS1/MAPK3/GAREM1/PDE8A/ZFP36/ID1/DAB2IP/PLCG1/PTPN11/ZPR1/IQGAP1/CFLAR
GOBP_POSITIVE_REGULATION_OF_SECRETION 216 0.3849591 1.453222 0.0047705 0.0466952 0.0376779 2462 PLA2G3/ACHE/TTN/HYAL3/SYT1/ITGAM/SNCA/ACSL4/IL1B/KMO/CNR1/CD177/EDN1/AACS/ADAM8/ANKRD1/IL1A/RAB8B/S100A8/BMP6/GPR68/STXBP1/PCK2/UNC13D/BMP2/C1QTNF1/TLR2/TGFB2/PTGES/TLR4/PTAFR/LRRC8A/HLA-F/INHBA/ADAM9/GPR27/ANO1/STX4/ATP13A2/IRS2/GAB2/DAB2/C1QTNF3/SOX4/CFTR/ISL1/RAB27B/GABBR1/F2RL1/GLUD1/TRPM4/SYK/PFKFB2/STX1A/P2RX4/DOC2B/SLC12A2/FRMD4A/IL4R/RAB27A
GOBP_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC 63 0.5014605 1.605747 0.0047858 0.0467466 0.0377194 1313 NTRK1/SYT1/MAPK8IP2/UNC13A/KMO/RELN/PTGS2/CNR1/DKK1/DGKI/GRIK4/TNF/STXBP1/GRM1/MEF2C/CACNG8
GOBP_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY 14 0.7620532 1.773575 0.0048871 0.0476360 0.0384370 2242 MICA/CEACAM1/LGALS9/SERPINB4/SERPINB9/HLA-G/KLRD1/HLA-F/HLA-E/HLA-B
GOBP_REGULATION_OF_ORGANIC_ACID_TRANSPORT 48 0.5620999 1.690935 0.0049047 0.0477081 0.0384952 2331 PLA2G3/ACSL1/SNCA/IL1B/KMO/THBS1/EDN1/CLTRN/IL1A/TNF/STXBP1/PTGES/IRS2/ACE2/GABBR1/SYK/ACSL5/P2RX4/SLC12A2
GOBP_NIK_NF_KAPPAB_SIGNALING 109 0.4474164 1.553345 0.0049321 0.0477760 0.0385500 2875 TCIM/TNFRSF10A/IL1B/CCN3/ZC3H12A/IL23A/BIRC3/EDN1/IFI35/NFKB2/RELB/TNF/RIPK3/NFKBIA/LGALS9/IKBKE/TLR2/NMI/RTKN2/IL18R1/TLR4/PTP4A3/GREM1/EIF2AK2/TNFSF14/NOD2/SPHK1/C1QTNF3/IRAK1/PTPN22/CARD10/HDAC7/ILK/TNFSF15/BCL3/TRAF2/TMSB4X/MALT1/NOD1/RBCK1/CD86/TRADD/IL18/TNFRSF10B
GOBP_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM 493 0.3265520 1.328524 0.0049224 0.0477760 0.0385500 4682 ADRA1A/TRIB3/NPC1/HSPB8/SNCA/RAB24/KDR/ADPRH/DEPP1/ZC3H12A/PLK3/UCHL1/FEZ1/MAP1LC3B2/LAMP3/S100A8/TICAM1/SREBF2/IKBKG/HDAC6/TP53INP2/TRIM21/DDIT3/ADRB2/TRIM5/GABARAPL1/DAPK3/RNF213/TRIM14/RUBCN/S100A9/MET/MTCL1/OPTN/ATP13A2/TPCN2/CHMP7/TMEM41B/WIPI1/ACER2/DRAM1/NOD2/IFI16/CAMKK2/STBD1/EEF1A2/BOK/SESN2/CHMP6/PTPN22/ARSB/EPM2A/MAPK3/RNF31/HAP1/VPS33B/VMP1/TAB3/PIP4K2A/SQSTM1/GPSM1/HMOX1/DAPK2/RIPK2/MCOLN1/TRIM22/SRC/VPS37B/NOD1/PLAA/RRAGC/AUP1/ATG2A/VIPAS39/PIP4K2C/TBC1D25/TIGAR/FOXK2/PIK3C2A/RHEB/ERN1/GABARAP/ITGB4/NEDD4/HK2/MAP1LC3B/ATP6V1E2/VPS18/RAB12/DEPDC5/FLCN/DDRGK1/MUL1/FEZ2/SH3GLB1/VCP/FZD5/EIF4G1/UBQLN4/CHMP1B/ATG13/ABL2/TRIM27/PLK2/TBC1D17/PIP4K2B/CHMP4C/WDR45/RETREG3/CTTN/TAFAZZIN/RAB43/PACS2/RMC1/VPS37D/EI24/PHF23/SMURF1/ZFYVE1/MCL1/ATP6V1B2/GSK3B/ULK3/ILRUN/RAB33B/HIF1A/VPS4A/KAT5/TRIM65/CHMP2B/ATG14/VPS37A/USP36/ATP6V0B/EXOC8/TP53/UFM1/STX12/PIKFYVE/RAB8A/ATP6V0A1/SPTLC2/RAB7A/MVB12A/AKT1/DAP/ARL8B/RAB19/EVA1A/GOLGA2/WDR81/PSEN1/SNF8/UBQLN1/TOLLIP/TECPR2/MTMR14/FNBP1L/SNX6/CPTP/ATG101/CALCOCO2/SYT11/QSOX1/ATP6V1H/ATG9A/HTT/TMEM208/GNAI3/RALB/PIK3CB/CHMP1A/ANXA7/FOXK1/ATG7/RAB5A/CHMP3/NRBP2/RPTOR/AP4M1/SBF2/PGAM5/PIK3CA/ORMDL3/TSPO
GOBP_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION 132 0.4279049 1.518798 0.0049832 0.0481713 0.0388689 3060 FGL2/TNFSF9/FOXP3/ZC3H12A/IL23A/CAMK4/IL4I1/ADAM8/CYP26B1/CD83/SOCS1/IL1RL2/LAG3/CARD11/VNN1/FANCA/LGALS9/PRDM1/HLA-G/INHBA/DUSP10/CD46/NFKBIZ/IL15RA/NFKBID/SOX4/IL7R/TOX/ZEB1/ANXA1/PTPN2/PRELID1/PNP/SYK/MMP14/RIPK2/MALT1/IL4R/CD86/IL15/IRF1/SOS2/IL18/ZBTB7B/BTN2A2/TGFBR2
GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY 48 0.5610552 1.687792 0.0050381 0.0486012 0.0392158 2242 CXCL6/MICA/ITGAM/IL23A/CEACAM1/LAG3/RIPK3/NOS2/LGALS9/SERPINB4/SERPINB9/RAET1E/ICAM1/HLA-G/KLRD1/HLA-F/PVR/CADM1/IL7R/HLA-E/F2RL1/HLA-B
GOBP_CYTOSKELETON_DEPENDENT_CYTOKINESIS 92 -0.4281094 -1.548039 0.0050912 0.0489604 0.0395057 1912 DCDC1/FMN2/CIT/ROPN1B/SEPTIN5/EFHC1/RACGAP1/STMN1/SEPTIN3/KIF23/ESPL1/KIF20B/ANLN/PLK1/KIF20A/KIF4A/CEP55
GOBP_NEGATIVE_REGULATION_OF_PHOSPHORYLATION 324 0.3508034 1.382017 0.0050963 0.0489604 0.0395057 3244 HMGCR/PAX6/MLXIPL/TRIB3/SLIT2/SLC8A1/NTRK3/PTPRH/XDH/SNCA/IL1B/ZC3H12A/CEACAM1/CDKN2B/DKK1/UCHL1/CDKN1C/SFN/SOCS1/SPRY4/OCLN/WARS1/JUN/PIK3IP1/SOCS3/FOXA2/BMP2/PMEPA1/TNFAIP3/ERRFI1/ENG/GPRC5A/PTPRO/PARP14/SH2B3/ENPP1/DUSP6/CDKN1A/PTPRJ/SPRY1/GREM1/RUBCN/CHP1/INHBA/DUSP10/GRB10/NIBAN1/ANKLE2/INCA1/CAMK2N1/IRAK3/DUSP3/CDKN2A/LYN/DBNDD1/TRIB1/IRS2/TRIB2/GADD45A/MAPK8IP1/PLPP3/MICAL1/CHMP6/PTPN22/DUSP1/DDIT4/ADAR/PTPN2/THY1/DUSP16/SPAG9/PIP4K2A/SMAD6/PRKRIP1/INPP5F/IGFBP3/YWHAG/BAK1/PIP4K2C/HYAL2/NCK1/TIGAR/PPIA/DAB2IP/PID1/STK38/LATS2/MYADM/SPRED2/SMPD1/SIRPA/SH3BP5/TWIST1/HEXIM1/CAV1/EIF4G1/TESK1
GOBP_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY 24 -0.6455287 -1.795745 0.0051069 0.0489612 0.0395063 2981 RPS20/RPL11/RPL23/RPS7/RPL37/RPL5/BAG2/FBXO5/MAD2L1/CDC20B/PLK1/CDC20/UBE2C
GOBP_CEREBROSPINAL_FLUID_CIRCULATION 13 -0.7641462 -1.819579 0.0051415 0.0491917 0.0396923 2878 ODAD4/DNAAF11/AQP4/CFAP54/DAW1/CCDC39/SPAG16/DNAH9/CFAP45/CFAP43/CFAP221
GOBP_REGULATION_OF_MEMBRANE_DEPOLARIZATION 35 0.6148128 1.752460 0.0051716 0.0493786 0.0398431 593 FZD9/SCN3B/IFI6/KDR/HSH2D/SCN1B/HCN3/HCN2
GOBP_STEROID_HORMONE_BIOSYNTHETIC_PROCESS 27 0.6347207 1.715480 0.0052111 0.0496548 0.0400659 2708 DHCR7/HSD17B7/HSD17B12/SRD5A3/BMP6/BMP2/HSD17B8/DAB2/EGR1/HSD17B1/WNT4
GOBP_CELLULAR_LIPID_CATABOLIC_PROCESS 182 0.4082613 1.512620 0.0052542 0.0499632 0.0403148 1887 PNPLA3/APOC1/ACAT2/LIPC/LIPG/LPIN1/LDLR/PLA2G4C/NUDT8/SRD5A3/GPCPD1/ACOXL/CNR1/SCARB1/ALDH1L2/MFSD2A/CYP26B1/ACADL/ENPP6/NEU1/PCK2/IDH1/ECH1/BCO1/LIPH/PLPP6/LIPE/GDPD3/ADTRP/CYP1B1/IRS2/ACER2/SPHK1/CPT1C/SESN2/PLA2G15

GOMF

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
GOMF_CHEMOKINE_RECEPTOR_BINDING 36 0.8302366 2.328789 0.0000000 0.0000002 0.0000001 842 DEFB4A/CXCL10/CXCL11/CCL22/CCL4/NES/CXCL9/CCL20/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/CXCL5/DEFB1/CXCL1/PF4V1/CX3CL1/CXCL16/STAT1
GOMF_CYTOKINE_ACTIVITY 122 0.6410433 2.240342 0.0000000 0.0000002 0.0000001 1708 CXCL10/CXCL11/IL19/CCL22/EBI3/CD70/IL36G/CCL4/CXCL9/CCL20/IL32/CXCL2/CXCL6/CXCL3/TNFSF9/CXCL8/FGF2/IL17C/LIF/CCL5/CLCF1/CXCL5/IL1B/BMP8B/CXCL1/CMTM3/IL23A/CSF3/NAMPT/EDN1/PF4V1/GDF15/INHBE/TNFSF13B/IL1RN/IL1A/CX3CL1/AREG/TNF/BMP6/CXCL16/VEGFA/BMP2/TGFB2/GREM1/IL11/INHBA/IL34/IL36A/CSF1/WNT7A/TNFSF14/SECTM1/CCL17
GOMF_CYTOKINE_RECEPTOR_BINDING 172 0.5867398 2.133656 0.0000000 0.0000002 0.0000001 3069 NTRK1/DEFB4A/CXCL10/CXCL11/CCL22/EBI3/CD70/IL36G/CCL4/NES/CXCL9/CCL20/CXCL2/CXCL6/CXCL3/TNFSF9/CXCL8/LIF/CCL5/CLCF1/CXCL5/IL1B/DEFB1/CXCL1/IL23A/SOCS2/CSF3/PF4V1/MYD88/TNFSF13B/IL1RN/IL1A/TMBIM1/CX3CL1/TNF/CXCL16/VEGFA/STAT1/PRLR/OSMR/ENG/TGFB2/SH2B3/GREM1/IL11/IL34/IL36A/CSF1/TRAF1/ITGB3/TNFSF14/CCL17/EFNA5/BID/PXDN/SYK/ADAM17/TNFSF15/SMAD6/TRAF2/CCRL2/TGFBR1/IL13RA1/YARS1/TYK2/LRG1/IL15/S100A14/TRADD/ECM1/IL18/DAB2IP/FADD/CASP8/SPRED2/PLCG1/ITGA5/TGFBR2/JAK1/TRAF5
GOMF_SIGNALING_RECEPTOR_REGULATOR_ACTIVITY 264 0.5218376 2.010299 0.0000000 0.0000002 0.0000001 2032 DEFB4A/PCSK9/CXCL10/CXCL11/IL19/CCL22/EBI3/CD70/IL36G/CCL4/CXCL9/CCL20/IL32/CXCL2/CXCL6/CXCL3/TNFSF9/CXCL8/FGF2/IL17C/LIF/EREG/CCL5/CLCF1/IGF2/CXCL5/IL1B/CGB7/SEMA3B/BMP8B/CXCL1/ADM2/CCN3/CMTM3/IL23A/OSGIN1/FST/CSF3/NAMPT/SEMA3D/EDN1/UTS2B/DKK1/PF4V1/GDF15/TYMP/STC2/INHBE/TNFSF13B/SEMA7A/IL1RN/IL1A/CX3CL1/FGF13/AREG/TNF/BMP6/CXCL16/VEGFA/COLEC10/HBEGF/UCN2/LYNX1/FGF1/ARTN/BMP2/MANF/MACC1/PDGFB/TGFB2/GNRH1/GREM1/IL11/INHBA/IL34/IL36A/FLRT2/EGF/CSF1/WNT7A/KL/TNFSF14/SECTM1/CCL17/FGF11/PTHLH/EFNA5/FAM3D/SCG2/MIA/PDGFC/METRNL/PXDN
GOMF_CHEMOKINE_ACTIVITY 25 0.8547067 2.269778 0.0000000 0.0000013 0.0000012 804 CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/CXCL5/CXCL1/PF4V1/CX3CL1/CXCL16
GOMF_CXCR_CHEMOKINE_RECEPTOR_BINDING 13 0.9320009 2.121029 0.0000001 0.0000181 0.0000164 720 CXCL10/CXCL11/CXCL9/CXCL2/CXCL6/CXCL3/CXCL8/CXCL5/CXCL1/PF4V1/CX3CL1
GOMF_ACYLTRANSFERASE_ACTIVITY 195 0.4676187 1.734899 0.0000179 0.0024097 0.0021815 1887 PNPLA3/ACAT2/HMGCS1/ELOVL6/ACLY/FASN/PLA2G4C/GGT7/LCAT/NAA80/ELOVL5/GGT5/ZDHHC14/ASPG/ABHD4/TGM4/ELOVL7/QPCTL/ZDHHC9/ZDHHC18/SPTSSA/GPAT3/PLAAT1/PIGW/ELOVL1/GCAT/PORCN/LPCAT1/PAFAH1B3/YKT6/SPHK1/HGSNAT/CPT1C/GPAT4/PLA2G15
GOMF_PROTEIN_HETERODIMERIZATION_ACTIVITY 262 -0.4035046 -1.645942 0.0000265 0.0031238 0.0028280 1250 H3C1/PDSS1/TPM2/H3C13/P2RY1/H2AC15/H3C10/SYT10/KCNB1/H2BC11/H2AC21/CYBA/MTTP/SLC51B/AURKA/H2BC3/H4C13/NPAS1/H2BC7/H2AC16/H2AC4/AOC3/H2AC13/ABCD2/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/ADRA2A/H3C12/H2BC17/H2BC13/ABCG1/TOP2A/H3C3/H2BC14/H3C8/H3C2
GOMF_DOUBLE_STRANDED_RNA_BINDING 66 0.6064721 1.939104 0.0000547 0.0057344 0.0051913 2574 ZBP1/OAS3/OASL/OAS1/OAS2/IFIH1/RFTN1/DDX60/EIF2AK2/MSN/SLC3A2/YRDC/DHX58/VIM/ADAR/NLRP1/PRKRIP1/TFRC
GOMF_ATP_DEPENDENT_ACTIVITY_ACTING_ON_DNA 100 -0.5216104 -1.883473 0.0000638 0.0060204 0.0054502 1109 DSCC1/HLTF/BRIP1/ATAD5/BLM/DNA2/RAD51/RECQL4/XRCC2/CHD1L/POLQ/RAD54B/RAD54L/ERCC6L/DMC1/TOP2A
GOMF_MICROTUBULE_MOTOR_ACTIVITY 62 -0.5821539 -1.917317 0.0000780 0.0066894 0.0060558 1712 KIF19/KIF1A/STARD9/KIF22/DNAH9/DYNC2H1/DNAI2/DNAH3/KIF21A/DNAH6/DNAH1/DNAH5/DYNLRB2/DNAH10/KIF11/DNAH2/DNAH12/KIF18A/KIF23/KIF14/KIF20B/KIF15/CENPE/KIF20A/KIF4A/KIF2C/KIFC1/KIF18B
GOMF_SULFUR_COMPOUND_BINDING 194 0.4607741 1.709665 0.0001024 0.0080485 0.0072862 1228 PNPLA3/CXCL10/CXCL11/FGFR4/LIPC/LIPG/FGFBP1/SLIT2/RTN4R/CXCL6/SERPINC1/CXCL8/FGF2/HSD17B12/SELL/PANK3/SMOC1/PANK1/COL13A1/NAA80/CCN3/THBS1/ADAMTS5/FST/PF4V1/CD34/LTBP2/VEGFA/ACADL/HBEGF/FBLN7/LAMC2/ADGRE2/FGF1/SAA1/LIPH/TPK1/FGFBP3/PTGES/CCN1/ENPP1
GOMF_CATALYTIC_ACTIVITY_ACTING_ON_DNA 205 -0.4098378 -1.621981 0.0001699 0.0123252 0.0111578 3322 PTGES3/CRY2/FEN1/LIG1/TOP1MT/MCM4/MRE11/POLH/WRN/RAD9A/NTHL1/CHD3/LIG3/POLI/PRIMPOL/RUVBL2/NEIL1/MGMT/ENDOG/FANCM/TENT4B/ERCC1/RFC3/ZGRF1/ZRANB3/XRCC3/POLN/DSCC1/HLTF/POLD1/BRIP1/MUTYH/ATAD5/BLM/FTO/DNA2/RAD51/RECQL4/XRCC2/CHD1L/POLQ/RAD54B/EXO1/RAD54L/NEIL3/ERCC6L/POLE2/DMC1/TOP2A
GOMF_G_PROTEIN_COUPLED_RECEPTOR_BINDING 162 0.4652855 1.681414 0.0001933 0.0130179 0.0117849 1015 DEFB4A/CXCL10/CXCL11/CCL22/CCL4/NES/CXCL9/CCL20/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/CXCL5/DEFB1/CXCL1/EDN1/UTS2B/FYN/PF4V1/UCHL1/CX3CL1/CXCL16/STAT1/UCN2/GNAZ/SAA1/HOMER3
GOMF_PROTEASE_BINDING 116 0.4966039 1.735643 0.0002407 0.0151326 0.0136993 3821 CD70/LDLR/TTN/SERPINC1/A2ML1/SELL/TNFRSF10A/DERL3/CD177/SERPINE1/VWF/TIMP2/TNF/SERPINB4/TNFAIP3/SERPINB9/CSTB/SELENOS/ITGB3/PANX1/COL1A1/BCL10/RFFL/SERPINF2/ITGAV/NTRK2/FURIN/RIPK2/ITGA3/MALT1/F3/DERL1/IL1R1/POLG/ECM1/FAP/CSTA/UBC/FADD/FLOT1/VCP/SYVN1/OS9/CFLAR/BIN1/PRNP/STIM1/TIMP1/SERPINB13/GSK3B/RIOK3/SERPINA1
GOMF_INTEGRIN_BINDING 123 0.4865914 1.704977 0.0002626 0.0154756 0.0140098 3082 ISG15/FGF2/ITGAM/KDR/IGF2/IL1B/ITGA9/VCAM1/CCN3/THBS1/ADAMTS5/CD177/VWF/ITGA10/SEMA7A/CX3CL1/LAMA3/FGF1/ITGB1BP2/ICAM1/CCN1/MFGE8/FERMT1/ITGB8/ADAM9/LCP1/ESM1/LYN/FRMD5/ITGB3/CD151/PLPP3/CCN4/ITGB7/PTPN2/ITGAV/THY1/SYK/ADAM17/CD9/ITGB6/TGFBI/MMP14/COL16A1/ITGA3/SRC/NRG1/PPIA/MYH9/FAP/P4HB/ITGB4/S1PR3/ITGA6/ITGA5/ITGB5
GOMF_ATP_DEPENDENT_ACTIVITY 475 -0.3272166 -1.419508 0.0002979 0.0165232 0.0149582 2152 CCT6B/PEX1/ABCC6/EP400/HSP90AA1/SMC4/FANCM/RFC3/DNAH7/ZGRF1/ABCA5/TDRD9/SMC2/ABCA9/PEX6/ZRANB3/ABCC9/KIF19/XRCC3/HSPA4L/ATP8B4/KIF1A/ATP2A3/STARD9/KIF22/HSPA1L/DNAH9/ACSBG1/ABCA10/ABCB11/DYNC2H1/ATP6V1C2/DNAI2/DNAH3/KATNAL2/KIF21A/DNAH6/ABCC11/ABCA8/DNAH1/DSCC1/DNAH5/ABCA6/ABCC2/HLTF/DYNLRB2/DNAH10/CLU/BRIP1/KIF11/ORC1/DNAH2/SLC26A1/TRIP13/ATAD5/DNAH12/BLM/HELLS/DNA2/RAD51/RECQL4/KIF18A/XRCC2/KIF23/ABCD2/CHD1L/KIF14/KIF20B/KIF15/POLQ/SLC4A8/RAD54B/CENPE/RAD54L/KIF20A/KIF4A/ERCC6L/KIF2C/DMC1/KIFC1/ABCA1/ABCG1/ATP2B3/TOP2A/KIF18B
GOMF_MICROTUBULE_BINDING 245 -0.3843725 -1.562871 0.0003257 0.0170645 0.0154483 2747 CCDC88C/DNM3/KIF27/CEP57/CEP57L1/CEP290/KIF24/CCDC181/CCDC66/MAP6/CCDC88A/EML6/GAS2L2/KIF6/RMDN2/TOGARAM2/CCDC61/APC2/SPAG8/CDK5/CFAP157/SAXO2/SAXO1/MTUS2/CCDC170/ABRAXAS1/DCDC1/CETN3/MAP1A/KIF19/KIF1A/STARD9/HOOK1/KIF22/CETN2/REEP1/CCDC187/MAP10/KATNAL2/MDM1/KIF21A/DNAI7/RACGAP1/NDRG1/SPATA4/LZTS1/RP1/KIF11/REEP2/KIF18A/PSRC1/KIF23/CENPF/SPC24/KIF14/KIF20B/CAPN6/FAM83D/KIF15/SPAG5/PLK1/CENPE/KIF20A/KIF4A/TPX2/DLGAP5/KIF2C/SKA1/KIFC1/GTSE1/BIRC5/KIF18B
GOMF_CYTOSKELETAL_MOTOR_ACTIVITY 92 -0.4867552 -1.745084 0.0003527 0.0175069 0.0158487 1926 DNAI1/DNAH7/KIF19/KIF1A/STARD9/KIF22/DNAH9/DYNC2H1/DNAI2/DNAH3/KIF21A/DNAH6/DNAH1/DNAH5/DYNLRB2/DNAH10/KIF11/DNAH2/DNAH12/KIF18A/KIF23/KIF14/KIF20B/KIF15/CENPE/KIF20A/KIF4A/KIF2C/KIFC1/KIF18B
GOMF_CARBOXYLIC_ESTER_HYDROLASE_ACTIVITY 107 0.4962078 1.714328 0.0004457 0.0205137 0.0185708 1359 PLA2G3/PNPLA3/ACHE/TNFAIP6/ACOT1/LIPC/LIPG/PLA2G4C/LCAT/ASPG/ABHD4/LIPA/LIPH/PTRH1/LIPE/GDPD3/PGAP6/PLAAT1/ACOT2
GOMF_GTPASE_ACTIVITY 280 0.4042636 1.564892 0.0004568 0.0205137 0.0185708 2832 RAB42/GEM/RGS7/RASD1/MX2/TUBB3/RGS16/MX1/RAB24/RAB32/RAB6C/ARL14/RAB40AL/RND1/TUBB2A/GBP5/GBP2/RAB8B/GTPBP2/RGS9/RHOB/RGS20/GBP1/GNAZ/RAP2B/RND3/RAB5B/TUBB6/RHOF/RRAS/GCH1/RASEF/REM1/SEPTIN11/AGAP2/GNA15/RAC3/GNA12/RAB4B/TUBA1C/EEF1A2/MRAS/GBP4/ARL8A/RAB27B/RHOG/RGS10/RAP1GAP/ARL9/RALA/RAB6A/RASD2/TUBA4A/KRAS/ATL3/RHOD/RHOC/ARF4/RAB27A/RRAGC/NRAS/RAB35/TUBB/GBP3/RHOBTB3/RAB30/RIT1/RAB9A/SEPTIN8/RHEB/ARF3
GOMF_DAMAGED_DNA_BINDING 68 -0.5308747 -1.789231 0.0004867 0.0208623 0.0188863 4027 PNKP/OGG1/ERCC4/RPA3/MSH6/MSH2/POT1/CRY2/FEN1/H2AX/POLH/WRN/SMC6/HMGB1/DDB2/NTHL1/MSH3/TP63/KDM4D/POLI/NEIL1/ERCC1/BRCA1/POLD1/MUTYH/HMGB2/BLM/RECQL4/POLQ/NEIL3
GOMF_TUBULIN_BINDING 335 -0.3513073 -1.464856 0.0005097 0.0208984 0.0189190 2747 CCDC88C/DNM3/TTLL9/KIF27/HSPH1/CEP57/CEP57L1/CEP290/FAM110C/BCAS3/DNAL1/KIF24/CCDC181/CCDC66/MAP6/AGBL4/CCDC88A/EML6/GAS2L2/KIF6/RMDN2/EFHC2/TOGARAM2/B9D2/CCDC61/APC2/ARL4C/SPAG8/PDE4B/CDK5/CFAP157/SAXO2/SAXO1/DIXDC1/STMND1/MTUS2/CCDC170/ABRAXAS1/DCDC1/IFT81/CETN3/MAP1A/KIF19/DLEC1/KIF1A/BRCA1/CENPJ/STARD9/HOOK1/KIF22/CETN2/EFHC1/REEP1/CCDC187/MAP10/KATNAL2/MDM1/KIF21A/DNAI7/RACGAP1/NDRG1/SPATA4/LZTS1/STMN1/RP1/KIF11/TTLL6/REEP2/PPP1R42/KIF18A/PSRC1/KIF23/CENPF/SPC24/KIF14/KIF20B/CAPN6/FAM83D/KIF15/SPAG5/PLK1/CENPE/KIF20A/KIF4A/TPX2/DLGAP5/KIF2C/SKA1/KIFC1/GTSE1/BIRC5/KIF18B
GOMF_GLYCOSAMINOGLYCAN_BINDING 153 0.4576352 1.639086 0.0005343 0.0209945 0.0190061 1721 TNFAIP6/CXCL10/CXCL11/FGFR4/LIPC/LIPG/FGFBP1/SLIT2/RTN4R/CXCL6/SERPINC1/CXCL8/FGF2/HSD17B12/SELL/SMOC1/COL13A1/CCN3/THBS1/CHODL/ADAMTS5/PGLYRP4/PF4V1/LTBP2/VEGFA/HBEGF/FBLN7/LAMC2/ADGRE2/FGF1/SAA1/LIPH/PGLYRP3/ENG/TLR2/FGFBP3/HAPLN3/CCN1/VIT/HMMR/COL5A3/FSTL1/SELP/PCOLCE2/NOD2
GOMF_CCR_CHEMOKINE_RECEPTOR_BINDING 18 0.7882652 1.941977 0.0006052 0.0228274 0.0206653 842 DEFB4A/CCL22/CCL4/NES/CCL20/CCL5/DEFB1/CX3CL1/STAT1
GOMF_PROTEIN_SELF_ASSOCIATION 51 0.5928301 1.802567 0.0007328 0.0265786 0.0240613 2384 ACHE/PCSK9/RSAD2/TTN/CCL5/ADAM8/MYD88/CARD11/TNFAIP3/DVL2/SPTBN5/BCL10/TMEM43/NLRP1/MALT1
GOMF_OXYGEN_BINDING 18 -0.7419081 -1.929381 0.0010335 0.0360945 0.0326759 1179 ADGB/CYP4B1/MB/NGB/CYGB/HBB/CYP2F1/CYP26A1
GOMF_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS 110 0.4934312 1.710695 0.0011534 0.0388464 0.0351671 3931 ZBP1/APOBEC3A/DPYSL2/HDAC9/HINT2/PGLYRP4/APOBEC3B/ASPG/CD101/MTHFD2/OPLAH/VNN1/HDAC6/PGLYRP3/CDA/GCH1/PDF/ARG2/ACER2/NTAQ1/ADAR/DDAH2/HDAC7/LACC1/HINT3/GDA/ACY3/SIRT7/NTAN1/DHODH/GLS/AMDHD2/APOBEC3F/APOBEC3G/TGM2/DPYSL3/PM20D2/DCTD/ADAT1/SIRT6
GOMF_PLUS_END_DIRECTED_MICROTUBULE_MOTOR_ACTIVITY 16 -0.7595711 -1.925207 0.0014941 0.0485848 0.0439832 1712 KIF19/KIF1A/KIF11/KIF18A/KIF14/KIF20B/CENPE/KIF18B

Reactome

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF 55 0.8599375 2.670809 0.0000000 0.0000000 0.0000000 364 MVD/HMGCS1/CYP51A1/ELOVL6/DHCR7/LSS/FDPS/HMGCR/INSIG1/IDI1/FDFT1/TM7SF2/SCD/SQLE/SC5D/FASN/MVK/HELZ2
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP 42 0.8846378 2.593326 0.0000000 0.0000000 0.0000000 364 MVD/HMGCS1/CYP51A1/ELOVL6/DHCR7/LSS/FDPS/HMGCR/IDI1/FDFT1/TM7SF2/SCD/SQLE/SC5D/FASN/MVK/HELZ2
REACTOME_HDACS_DEACETYLATE_HISTONES 81 -0.7297199 -2.531763 0.0000000 0.0000000 0.0000000 1352 SAP30/H3C1/H3C13/H2AC15/H3C10/H2BC11/H2AC21/H2BC3/H4C13/H2AC14/H2BC7/H2AC16/H2AC4/H2AC13/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_CHOLESTEROL_BIOSYNTHESIS 24 0.9496592 2.509335 0.0000000 0.0000000 0.0000000 398 MVD/ACAT2/HMGCS1/CYP51A1/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/IDI1/HSD17B7/FDFT1/TM7SF2/NSDHL/SQLE/SC5D/MVK/DHCR24
REACTOME_METABOLISM_OF_STEROIDS 126 0.7108781 2.477691 0.0000000 0.0000000 0.0000000 620 MVD/ACAT2/HMGCS1/CYP51A1/ELOVL6/EBP/DHCR7/LSS/FDPS/MSMO1/HMGCR/INSIG1/IDI1/HSD17B7/FDFT1/TM7SF2/NSDHL/SCD/SQLE/STARD4/SC5D/FASN/MVK/HSD17B12/HELZ2/DHCR24/SRD5A3/CYP46A1/SLCO1B1
REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES 61 -0.7408130 -2.469931 0.0000000 0.0000000 0.0000000 3093 H4C2/NCAPG2/H2AX/H2AZ2/H3C6/H2BC6/H4C6/NCAPD3/PHF8/H2BC15/H2BC9/H3-3A/H3C11/SMC4/H4C12/H2BC12/H4C4/SMC2/H3C1/H3C13/H3C10/H2BC11/H2BC3/CCNB1/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/CDK1/PLK1/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES 66 -0.7235302 -2.431173 0.0000000 0.0000000 0.0000000 1250 H3C1/H3C13/H2AC15/H3C10/H2AC21/H4C13/H2AC14/H2AC16/H2AC4/H2AC13/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H3C3/H3C8/H3C2
REACTOME_HATS_ACETYLATE_HISTONES 128 -0.6533711 -2.423903 0.0000000 0.0000000 0.0000000 1250 H3C1/H3C13/H2AC15/H3C10/H2BC11/H2AC21/H2BC3/H4C13/H2AC14/H2BC7/H2AC16/H2AC4/H2AC13/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 54 0.7795495 2.407983 0.0000000 0.0000000 0.0000000 1942 IFIT2/MX2/ISG15/RSAD2/IFITM1/IFIT1/IFIT3/OAS3/OASL/ISG20/IFI6/OAS1/MX1/XAF1/OAS2/IFI27/BST2/IRF7/USP18/IFI35/IFITM3/GBP2/SOCS1/STAT1/IFIT5/SOCS3/HLA-G/HLA-F/HLA-C/STAT2/IRF9/HLA-E/ADAR
REACTOME_CELL_CYCLE_CHECKPOINTS 281 -0.5818605 -2.407481 0.0000000 0.0000000 0.0000000 879 H2BC11/BRIP1/ANAPC4/ORC1/CCNE1/MAD1L1/H2BC3/CCNB1/H4C13/CENPU/CENPP/BLM/H2BC7/CDCA8/CDC25C/CCNA2/DNA2/CDC25A/CENPK/KIF18A/ZWINT/SGO2/CENPF/CLSPN/SPC24/H2BC10/H4C1/CCNE2/MAD2L1/H4C9/KNL1/CDK1/NDC80/PLK1/CENPE/EXO1/CCNB2/H2BC17/BUB1/ERCC6L/NUF2/H2BC13/KIF2C/MCM10/SKA1/CDC20/CDC45/SGO1/GTSE1/BUB1B/UBE2C/BIRC5/H2BC14/SPC25
REACTOME_DNA_REPLICATION 176 -0.6161768 -2.402321 0.0000000 0.0000000 0.0000000 1250 H3C1/ORC6/H3C13/POLD1/H3C10/GINS1/H2BC11/ANAPC4/ORC1/CCNE1/H2BC3/E2F1/H4C13/H2AC14/H2BC7/CCNA2/DNA2/GINS2/H2AC4/CDT1/H2BC10/E2F2/H4C1/CCNE2/H3C7/H4C9/H3C12/H2BC17/POLE2/H2BC13/MCM10/CDC45/UBE2C/H3C3/H2BC14/H3C8/H3C2
REACTOME_MITOTIC_SPINDLE_CHECKPOINT 108 -0.6666410 -2.401590 0.0000000 0.0000000 0.0000000 861 ANAPC4/MAD1L1/CENPU/CENPP/CDCA8/CENPK/KIF18A/ZWINT/SGO2/CENPF/SPC24/MAD2L1/KNL1/NDC80/PLK1/CENPE/BUB1/ERCC6L/NUF2/KIF2C/SKA1/CDC20/SGO1/BUB1B/UBE2C/BIRC5/SPC25
REACTOME_DNA_REPLICATION_PRE_INITIATION 133 -0.6173981 -2.279230 0.0000000 0.0000000 0.0000000 1250 H3C1/ORC6/H3C13/H3C10/H2BC11/ORC1/H2BC3/E2F1/H4C13/H2AC14/H2BC7/H2AC4/CDT1/H2BC10/E2F2/H4C1/H3C7/H4C9/H3C12/H2BC17/POLE2/H2BC13/MCM10/CDC45/H3C3/H2BC14/H3C8/H3C2
REACTOME_INTERFERON_SIGNALING 170 0.6192385 2.269829 0.0000000 0.0000000 0.0000000 3219 IFIT2/MX2/ISG15/RSAD2/IFITM1/IFIT1/IFIT3/OAS3/OASL/ISG20/IFI6/OAS1/MX1/XAF1/OAS2/IFI27/BST2/VCAM1/IRF7/HERC5/USP18/IFI35/IFITM3/GBP5/GBP2/PML/SOCS1/TRIM31/STAT1/IFIT5/GBP1/SOCS3/UBE2L6/TRIM21/IFNGR1/TRIM5/PTAFR/ICAM1/HLA-G/TRIM14/HLA-F/MT2A/EIF2AK2/HLA-C/STAT2/SP100/IRF9/GBP4/HLA-E/ADAR/TRIM25/MAPK3/PTPN2/TRIM29/SEC13/IFITM2/HLA-B/TRIM22/FLNA/TYK2/KPNA2/EGR1/GBP3/IRF1/UBC/NEDD4/PLCG1/HLA-A/PTPN11/JAK1/EIF4A1/IFNGR2/EIF4G1
REACTOME_M_PHASE 390 -0.5162866 -2.197544 0.0000000 0.0000000 0.0000000 879 H2BC11/ANAPC4/MAD1L1/H2BC3/CCNB1/H4C13/CENPU/CENPP/H2AC14/LMNB1/TUBB8B/H2BC7/CDCA8/CENPK/KIF18A/ZWINT/PTTG1/H2AC4/KIF23/SGO2/CENPF/SPC24/ESPL1/H2BC10/H4C1/H3C7/MAD2L1/H4C9/KNL1/CDK1/NDC80/PLK1/CENPE/NEK2/CCNB2/PLK4/KIF20A/CDCA5/H3C12/H2BC17/BUB1/ERCC6L/NUF2/H2BC13/KIF2C/SKA1/CDC20/NCAPH/SGO1/BUB1B/UBE2C/BIRC5/H3C3/H2BC14/NCAPG/SPC25/H3C8/H3C2
REACTOME_RHO_GTPASE_EFFECTORS 290 -0.4936626 -2.045378 0.0000000 0.0000000 0.0000000 879 H2BC11/CYBA/MAD1L1/H2BC3/H4C13/CENPU/CENPP/H2AC14/WAS/TUBB8B/H2BC7/CDCA8/CDC25C/CENPK/KIF18A/ZWINT/H2AC4/SGO2/CENPF/SPC24/KIF14/H2BC10/H4C1/H3C7/MAD2L1/H4C9/KNL1/DIAPH3/NDC80/PLK1/CENPE/H3C12/H2BC17/BUB1/ERCC6L/NUF2/H2BC13/KIF2C/SKA1/CDC20/IQGAP3/SGO1/BUB1B/BIRC5/H3C3/H2BC14/SPC25/H3C8/H3C2
REACTOME_HCMV_LATE_EVENTS 103 -0.6565035 -2.376337 0.0000000 0.0000000 0.0000000 1250 H3C1/H3C13/H2AC15/H3C10/H2BC11/H2AC21/H2BC3/H4C13/H2AC14/H2BC7/H2AC16/H2AC4/H2AC13/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION 115 -0.6274596 -2.269102 0.0000000 0.0000000 0.0000000 758 MAD1L1/CCNB1/CENPU/CENPP/TUBB8B/CDCA8/CENPK/KIF18A/ZWINT/SGO2/CENPF/SPC24/MAD2L1/KNL1/CDK1/NDC80/PLK1/CENPE/CCNB2/CDCA5/BUB1/ERCC6L/NUF2/KIF2C/SKA1/CDC20/SGO1/BUB1B/BIRC5/SPC25
REACTOME_CHROMATIN_MODIFYING_ENZYMES 255 -0.4983274 -2.053000 0.0000000 0.0000000 0.0000000 3023 H2AX/H2AZ2/RPS2/ING4/H3C6/SUPT20H/H2BC6/KMT5C/HDAC8/H4C6/CHD3/KDM4D/SMYD3/PHF8/H2BC15/H2BC9/RUVBL2/SMARCD3/SMARCE1/EP400/H3C11/H4C12/H2BC12/SMYD2/H4C4/JADE1/SAP30/H3C1/H3C13/H2AC15/H3C10/EZH2/H2BC11/H2AC21/H2BC3/H4C13/H2AC14/H2BC7/H2AC16/H2AC4/H2AC13/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS 95 -0.6507245 -2.318090 0.0000000 0.0000000 0.0000000 3232 NUP54/NUP155/H4C2/H2AX/H2AZ2/POLR2I/H3C6/H2BC6/H4C6/NDC1/H2BC15/H2BC9/H3-3A/H3C11/H4C12/H2BC12/H4C4/NUP37/H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 97 -0.6584022 -2.355073 0.0000000 0.0000000 0.0000000 2377 H2BC15/H2BC9/H3-3A/H3C11/H4C12/TNRC6C/H2BC12/H4C4/ATP2A3/NOTCH1/H3C1/MIR200B/ST3GAL3/H3C13/H3C10/H2BC11/H2BC3/E2F1/ST3GAL6/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/MIR449C/H3C3/H2BC14/H3C8/H3C2
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE 223 -0.5175649 -2.096812 0.0000000 0.0000000 0.0000000 861 ANAPC4/MAD1L1/CCNB1/CENPU/CENPP/LMNB1/TUBB8B/CDCA8/CENPK/KIF18A/ZWINT/PTTG1/SGO2/CENPF/SPC24/ESPL1/MAD2L1/KNL1/CDK1/NDC80/PLK1/CENPE/CCNB2/CDCA5/BUB1/ERCC6L/NUF2/KIF2C/SKA1/CDC20/SGO1/BUB1B/UBE2C/BIRC5/SPC25
REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA 61 -0.7252284 -2.417970 0.0000000 0.0000000 0.0000000 2377 H2BC15/H2BC9/H3-3A/H3C11/H4C12/H2BC12/H4C4/PHF19/H3C1/H3C13/H3C10/EZH2/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_MITOTIC_PROMETAPHASE 191 -0.5502065 -2.171767 0.0000000 0.0000000 0.0000000 758 MAD1L1/CCNB1/CENPU/CENPP/TUBB8B/CDCA8/CENPK/KIF18A/ZWINT/SGO2/CENPF/SPC24/MAD2L1/KNL1/CDK1/NDC80/PLK1/CENPE/NEK2/CCNB2/PLK4/CDCA5/BUB1/ERCC6L/NUF2/KIF2C/SKA1/CDC20/NCAPH/SGO1/BUB1B/BIRC5/NCAPG/SPC25
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE 78 -0.6826630 -2.354830 0.0000000 0.0000000 0.0000000 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS 178 -0.5524789 -2.149772 0.0000000 0.0000000 0.0000000 861 ANAPC4/MAD1L1/CENPU/CENPP/TUBB8B/CDCA8/CENPK/KIF18A/ZWINT/PTTG1/SGO2/CENPF/SPC24/ESPL1/MAD2L1/KNL1/NDC80/PLK1/CENPE/CDCA5/BUB1/ERCC6L/NUF2/KIF2C/SKA1/CDC20/SGO1/BUB1B/UBE2C/BIRC5/SPC25
REACTOME_MEIOTIC_RECOMBINATION 70 -0.6988848 -2.373989 0.0000000 0.0000000 0.0000000 2377 H2BC15/MSH5/H2BC9/H3-3A/PSMC3IP/H3C11/H4C12/H2BC12/H4C4/BRCA1/H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/BLM/H2BC7/RAD51/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/DMC1/H3C3/H2BC14/H3C8/H3C2
REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 96 -0.6442307 -2.299286 0.0000000 0.0000000 0.0000000 1352 SAP30/H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_DNA_METHYLATION 52 -0.7400772 -2.393995 0.0000000 0.0000000 0.0000000 1250 H2BC15/H2BC9/H3-3A/H3C11/H4C12/H2BC12/H4C4/H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION 64 -0.7174191 -2.399446 0.0000000 0.0000000 0.0000000 1250 H4C2/H2AX/H2AZ2/H3C6/H2BC6/H4C6/CHD3/H2BC15/H2BC9/H3-3A/H3C11/H4C12/H2BC12/H4C4/H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION 79 -0.6753202 -2.338579 0.0000000 0.0000000 0.0000000 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION 98 -0.6395745 -2.292337 0.0000000 0.0000001 0.0000000 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 94 -0.6468797 -2.290400 0.0000000 0.0000001 0.0000000 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_MEIOSIS 95 -0.6333176 -2.256081 0.0000000 0.0000001 0.0000000 2433 SYNE1/H2BC15/MSH5/H2BC9/H3-3A/PSMC3IP/H3C11/H4C12/H2BC12/H4C4/BRCA1/H3C1/SYCP2/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/LMNB1/BLM/H2BC7/RAD51/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/DMC1/H3C3/H2BC14/H3C8/H3C2
REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION 57 -0.7411435 -2.453905 0.0000000 0.0000001 0.0000001 1250 H3C1/ORC6/H3C13/H3C10/H2BC11/ORC1/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_GENE_SILENCING_BY_RNA 123 -0.5952829 -2.190296 0.0000000 0.0000001 0.0000001 3287 MIR23B/NUP54/NUP155/H4C2/H2AX/TDRD6/H2AZ2/PIWIL2/POLR2I/H3C6/H2BC6/H4C6/TDRD1/NDC1/H2BC15/H2BC9/H3-3A/PLD6/H3C11/HSP90AA1/MYBL1/H4C12/TNRC6C/H2BC12/H4C4/NUP37/TDRD9/H3C1/H3C13/H3C10/ANG/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH 89 -0.6409563 -2.246587 0.0000000 0.0000001 0.0000001 1250 H3C1/H3C13/H3C10/EZH2/H2BC11/H2BC3/H4C13/H2AC14/LMNB1/H2BC7/CDC25C/CDC25A/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_CELLULAR_SENESCENCE 181 -0.5312325 -2.073201 0.0000000 0.0000001 0.0000001 1108 H3C13/H3C10/EZH2/H2BC11/CBX2/ANAPC4/CCNE1/H2BC3/E2F1/H4C13/H2AC14/LMNB1/H2BC7/CCNA2/CDKN2C/H2AC4/H2BC10/MAP2K6/E2F2/H4C1/CCNE2/H3C7/H4C9/H1-5/H3C12/H2BC17/H1-1/H2BC13/UBE2C/H3C3/H2BC14/H3C8/H3C2
REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION 56 -0.7285613 -2.405405 0.0000000 0.0000001 0.0000001 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX 78 -0.6636967 -2.289406 0.0000000 0.0000002 0.0000001 2454 TLE3/H2BC15/H2BC9/H3-3A/H3C11/H4C12/H2BC12/H4C4/TCF7/AXIN2/H3C1/H3C13/LEF1/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3 53 -0.7346422 -2.401499 0.0000000 0.0000002 0.0000002 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION 134 -0.5698088 -2.108058 0.0000000 0.0000002 0.0000002 1352 SAP30/H3C1/H3C13/H3C10/EZH2/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS 112 -0.5962855 -2.158983 0.0000000 0.0000003 0.0000002 1250 H3C1/H3C13/H3C10/H2BC11/MYB/H2BC3/GATA2/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS 74 -0.6658665 -2.280635 0.0000000 0.0000004 0.0000003 1250 H3C1/H3C13/LEF1/H3C10/H2BC11/MYB/H2BC3/E2F1/GATA2/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_MITOTIC_PROPHASE 130 -0.5643673 -2.090293 0.0000000 0.0000006 0.0000005 3232 NUP54/NUP155/TMPO/H4C2/NCAPG2/H2AX/H2AZ2/PRKCA/H3C6/H2BC6/H4C6/NCAPD3/PHF8/NDC1/H2BC15/H2BC9/H3-3A/H3C11/SMC4/H4C12/H2BC12/VRK1/H4C4/NUP37/SMC2/H3C1/H3C13/H3C10/H2BC11/H2BC3/CCNB1/H4C13/H2AC14/LMNB1/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/CDK1/PLK1/CCNB2/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP 99 -0.5951460 -2.140480 0.0000000 0.0000008 0.0000007 1250 H3C1/H3C13/H3C10/H2BC11/ANAPC4/H2BC3/H4C13/H2AC14/H2BC7/CCNA2/CDKN2C/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/UBE2C/H3C3/H2BC14/H3C8/H3C2
REACTOME_HOMOLOGY_DIRECTED_REPAIR 130 -0.5567461 -2.062066 0.0000000 0.0000012 0.0000009 3741 NSD2/ERCC4/POLD3/RFC5/RPA3/BARD1/TIMELESS/RPS27A/H4C3/ATRIP/FEN1/ATM/RAD9B/ATR/H4C2/H2AX/MRE11/POLH/WRN/RAD52/H2BC6/RAD9A/RMI1/H4C6/LIG3/H2BC15/H2BC9/H4C12/ERCC1/RFC3/H2BC12/ABRAXAS1/H4C4/XRCC3/BRCA1/EME1/RMI2/POLD1/H2BC11/BRIP1/H2BC3/H4C13/BLM/H2BC7/CCNA2/DNA2/RAD51/XRCC2/RAD51AP1/CLSPN/H2BC10/H4C1/POLQ/H4C9/EXO1/H2BC17/POLE2/H2BC13/H2BC14
REACTOME_CHROMOSOME_MAINTENANCE 126 -0.5714214 -2.117202 0.0000001 0.0000014 0.0000011 3694 POLD3/MIS18BP1/RFC5/RPA3/RUVBL1/NPM1/H4C3/POT1/SHQ1/FEN1/LIG1/H4C2/CENPW/H2AX/H2AZ2/POLR2I/WRN/H2BC6/H4C6/CENPM/H2BC15/H2BC9/RUVBL2/H3-3A/WRAP53/CENPC/H4C12/MIS18A/RFC3/CENPH/H2BC12/H4C4/DSCC1/POLD1/H2BC11/H2BC3/H4C13/CENPU/CENPP/H2AC14/BLM/H2BC7/CCNA2/DNA2/CENPK/H2AC4/H2BC10/H4C1/OIP5/H4C9/KNL1/H2BC17/H2BC13/H2BC14/HJURP
REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE 111 -0.5807097 -2.102714 0.0000001 0.0000016 0.0000013 1250 H3C1/H3C13/H3C10/EZH2/H2BC11/CBX2/H2BC3/E2F1/H4C13/H2AC14/H2BC7/CDKN2C/H2AC4/H2BC10/MAP2K6/E2F2/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RHO_GTPASES_ACTIVATE_PKNS 78 -0.6327971 -2.182819 0.0000001 0.0000024 0.0000019 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/CDC25C/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION 134 -0.5421804 -2.005844 0.0000001 0.0000025 0.0000020 3093 H4C2/BCL2/H2AX/H2AZ2/POLR2I/H3C6/ERBB4/H2BC6/H4C6/TLE3/H2BC15/H2BC9/TFF3/H3-3A/H3C11/HSP90AA1/H4C12/TNRC6C/H2BC12/H4C4/NR5A2/H3C1/H3C13/H3C10/H2BC11/MYB/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION 81 -0.6196588 -2.149906 0.0000001 0.0000031 0.0000025 1250 H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES 24 0.8461576 2.235847 0.0000002 0.0000041 0.0000032 804 CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/CCR3/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/CXCL5/CXCL1/CX3CL1/CXCL16
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 63 -0.6681976 -2.230987 0.0000002 0.0000041 0.0000033 879 H4C2/CENPW/H2AX/H2AZ2/H2BC6/H4C6/CENPM/H2BC15/H2BC9/CENPC/H4C12/MIS18A/CENPH/H2BC12/H4C4/H2BC11/H2BC3/H4C13/CENPU/CENPP/H2AC14/H2BC7/CENPK/H2AC4/H2BC10/H4C1/OIP5/H4C9/KNL1/H2BC17/H2BC13/H2BC14/HJURP
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR 159 -0.5088214 -1.945037 0.0000002 0.0000044 0.0000035 3741 NSD2/ERCC4/POLD3/RFC5/RPA3/APBB1/BARD1/TIMELESS/RPS27A/H4C3/ATRIP/FEN1/ATM/RAD9B/ATR/H4C2/H2AX/MRE11/POLH/WRN/RAD52/H2BC6/RAD9A/RMI1/H4C6/LIG3/H2BC15/H2BC9/H4C12/ERCC1/RFC3/H2BC12/ABRAXAS1/H4C4/XRCC3/BRCA1/EME1/RMI2/POLD1/H2BC11/BRIP1/H2BC3/H4C13/BLM/H2BC7/CCNA2/DNA2/RAD51/XRCC2/RAD51AP1/CLSPN/H2BC10/H4C1/POLQ/H4C9/EXO1/H2BC17/POLE2/H2BC13/H2BC14
REACTOME_HCMV_EARLY_EVENTS 117 -0.5653891 -2.051817 0.0000002 0.0000046 0.0000037 1108 H3C1/H3C13/H2AC15/H3C10/EZH2/H2BC11/H2AC21/H2BC3/H4C13/H2AC14/TUBB8B/H2BC7/H2AC16/H2AC4/H2AC13/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_AMYLOID_FIBER_FORMATION 85 -0.6036647 -2.119157 0.0000003 0.0000054 0.0000043 1250 H2BC15/H2BC9/H3-3A/H3C11/LYZ/H4C12/H2BC12/H4C4/APOE/H3C1/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/LTF/H2AC4/CALB1/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_RHO_GTPASES_ACTIVATE_FORMINS 129 -0.5546380 -2.055895 0.0000003 0.0000054 0.0000043 758 MAD1L1/CENPU/CENPP/TUBB8B/CDCA8/CENPK/KIF18A/ZWINT/SGO2/CENPF/SPC24/MAD2L1/KNL1/DIAPH3/NDC80/PLK1/CENPE/BUB1/ERCC6L/NUF2/KIF2C/SKA1/CDC20/SGO1/BUB1B/BIRC5/SPC25
REACTOME_BASE_EXCISION_REPAIR 81 -0.6058978 -2.102162 0.0000004 0.0000072 0.0000057 4080 H2BC4/H2BC5/TERF1/PNKP/OGG1/POLD3/RFC5/RPA3/H4C3/POT1/FEN1/LIG1/H4C2/H2AX/H2AZ2/H2BC6/H4C6/NTHL1/LIG3/H2BC15/H2BC9/NEIL1/H4C12/RFC3/H2BC12/H4C4/POLD1/H2BC11/MUTYH/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H4C9/H2BC17/NEIL3/POLE2/H2BC13/H2BC14
REACTOME_REPRODUCTION 108 -0.5714519 -2.058669 0.0000004 0.0000073 0.0000058 1250 SYNE1/H2BC15/MSH5/H2BC9/H3-3A/PSMC3IP/H3C11/H4C12/H2BC12/H4C4/ADAM20/BRCA1/H3C1/SYCP2/H3C13/H3C10/H2BC11/H2BC3/H4C13/H2AC14/LMNB1/BLM/H2BC7/CATSPERD/RAD51/H2AC4/OVGP1/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/DMC1/H3C3/H2BC14/H3C8/H3C2
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION 147 -0.5286360 -1.996502 0.0000004 0.0000081 0.0000064 837 DHFR/ORC1/CCNE1/E2F1/CCNB1/CCNA2/CDC25A/TYMS/CDKN2C/CDT1/E2F2/CCNE2/CDK1/TK1/POLE2/MCM10/RRM2/CDC45/TOP2A/MYBL2
REACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE 70 -0.6325423 -2.148635 0.0000005 0.0000093 0.0000074 879 H1-3/H4C3/POT1/ATM/H1-2/H4C2/H2AX/H2AZ2/MRE11/H2BC6/H4C6/H2BC15/H2BC9/EP400/H4C12/H2BC12/H4C4/H2BC11/CCNE1/H2BC3/H4C13/H2AC14/LMNB1/H2BC7/CCNA2/H2AC4/H2BC10/H4C1/CCNE2/H4C9/H1-5/H2BC17/H1-1/H2BC13/H2BC14
REACTOME_HDMS_DEMETHYLATE_HISTONES 45 -0.7082012 -2.199619 0.0000005 0.0000095 0.0000076 1250 H3C1/H3C13/H3C10/H4C13/H4C1/H3C7/H4C9/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_NOTCH 217 -0.4642484 -1.873677 0.0000005 0.0000096 0.0000076 1427 HEY2/NBEA/NOTCH1/H3C1/MIR200B/ST3GAL3/H3C13/H3C10/H2BC11/DLL1/H2BC3/E2F1/ST3GAL6/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/TACC3/H3C7/H4C9/HEYL/H3C12/H2BC17/DLGAP5/H2BC13/MIR449C/H3C3/H2BC14/H3C8/H3C2
REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS 92 -0.5810360 -2.045257 0.0000006 0.0000101 0.0000080 3628 RFC5/RPA3/BARD1/TIMELESS/RPS27A/H4C3/ATRIP/ATM/RAD9B/ATR/H4C2/H2AX/MRE11/WRN/H2BC6/RAD9A/RMI1/H4C6/H2BC15/H2BC9/H4C12/RFC3/H2BC12/ABRAXAS1/H4C4/BRCA1/RMI2/H2BC11/BRIP1/H2BC3/H4C13/BLM/H2BC7/CCNA2/DNA2/CLSPN/H2BC10/H4C1/H4C9/EXO1/H2BC17/H2BC13/H2BC14
REACTOME_HCMV_INFECTION 141 -0.5226667 -1.953281 0.0000006 0.0000108 0.0000086 1108 H3C13/H2AC15/H3C10/EZH2/H2BC11/H2AC21/H2BC3/H4C13/H2AC14/TUBB8B/H2BC7/H2AC16/H2AC4/H2AC13/H2BC10/H4C1/H3C7/H2AC11/H4C9/H2AC12/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS 21 -0.8357522 -2.245483 0.0000009 0.0000150 0.0000120 861 ANAPC4/MAD2L1/CDC20/BUB1B/UBE2C
REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 26 -0.8015212 -2.233662 0.0000010 0.0000164 0.0000130 861 ANAPC4/MAD2L1/NEK2/CDC20/BUB1B/UBE2C
REACTOME_INTERLEUKIN_10_SIGNALING 33 0.7689498 2.161439 0.0000010 0.0000164 0.0000130 1443 CXCL10/CCL22/CCL4/CCL20/CXCL2/CXCL8/LIF/IL1R2/CCL5/IL1B/CXCL1/PTGS2/CSF3/IL1RN/IL1A/TNF/TNFRSF1B/PTAFR/ICAM1/CSF1
REACTOME_G2_M_CHECKPOINTS 160 -0.5054712 -1.935551 0.0000010 0.0000164 0.0000130 2014 H4C12/RFC3/H2BC12/ABRAXAS1/H4C4/BRCA1/PKMYT1/CDC7/RMI2/ORC6/H2BC11/BRIP1/ORC1/H2BC3/CCNB1/H4C13/BLM/H2BC7/CDC25C/DNA2/CDC25A/CLSPN/H2BC10/H4C1/H4C9/CDK1/EXO1/CCNB2/H2BC17/H2BC13/MCM10/CDC45/GTSE1/H2BC14
REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS 104 -0.5712376 -2.062994 0.0000010 0.0000166 0.0000132 1250 H3C1/H3C13/H3C10/EZH2/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT 89 -0.5755638 -2.017383 0.0000011 0.0000175 0.0000139 3628 RFC5/RPA3/BARD1/H4C3/ATRIP/ATM/RAD9B/ATR/H4C2/H2AX/MRE11/WRN/H2BC6/RAD9A/RMI1/H4C6/H2BC15/H2BC9/H4C12/RFC3/H2BC12/ABRAXAS1/H4C4/BRCA1/RMI2/H2BC11/BRIP1/H2BC3/CCNB1/H4C13/BLM/H2BC7/CDC25C/DNA2/H2BC10/H4C1/H4C9/CDK1/EXO1/H2BC17/H2BC13/H2BC14
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION 90 -0.5800455 -2.032389 0.0000011 0.0000178 0.0000142 4457 RPS11/RPS26/RPL18/RPS16/RPL18A/RPS24/RPL23A/RPL24/RPS5/RPS27/RPS12/RPL27/RPL9/RPS8/EEF1B2/RPL7A/EEF2/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/RPL41/RPL27A/RPL37A/RPL34/RPS15A/RPS28/RPS29/RPL3/RPS2/RPS20/RPS13/RPS4Y1/EEF1A1/RPL29/RPS23/RPL11/RPS25/RPL4/RPL30/RPL21/RPL23/RPL31/RPL13A/RPL32/RPL35A/RPL26L1/RPS6/RPSA/RPS4X/RPL15/RPS7/RPL6/RPL37/RPS18/RPL22/RPS14/RPL7/RPL5/RPL10A/RPS3A/RPS10/RPL39L
REACTOME_INTERFERON_GAMMA_SIGNALING 76 0.6294404 2.049693 0.0000022 0.0000346 0.0000275 3165 OAS3/OASL/OAS1/OAS2/VCAM1/IRF7/GBP5/GBP2/PML/SOCS1/TRIM31/STAT1/GBP1/SOCS3/TRIM21/IFNGR1/TRIM5/PTAFR/ICAM1/HLA-G/TRIM14/HLA-F/MT2A/HLA-C/SP100/IRF9/GBP4/HLA-E/TRIM25/PTPN2/TRIM29/HLA-B/TRIM22/GBP3/IRF1/HLA-A/PTPN11/JAK1/IFNGR2
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION 228 0.4751126 1.796361 0.0000027 0.0000410 0.0000326 2336 LUM/CAPN14/SDC3/FGF2/ITGAM/KDR/MMP25/MMP16/MMP10/MATN3/MMP17/COL13A1/ITGA9/VCAM1/CAPN12/THBS1/CEACAM1/ADAMTS14/ADAMTS5/PECAM1/COL6A3/SERPINE1/ADAM8/VWF/ITGA10/LTBP2/EMILIN2/KLK7/TIMP2/CEACAM6/LAMA3/MMP19/LAMC2/CD47/LAMB3/LOXL2/BMP2/COL6A1/PDGFB/TGFB2/MMP15/COLGALT2/ICAM1/COL9A2/MFAP2/ADAMTS9/ITGB8/PLOD3/ADAM9/MMP7/COLGALT1/ITGB3/MMP12/COL5A3/FMOD/COL1A1/COL22A1/CD151/PCOLCE2/LTBP1/HSPG2/MMP13/ITGB7/COL8A2/CTSV/PXDN/ITGAV/COL12A1/MMP24/ADAM17/FURIN/ITGB6/SERPINH1/MMP14/CAPN13/COL25A1/ADAMTS1/COL16A1/LAMC1/COL17A1/CAPN2/ITGA3
REACTOME_DNA_REPAIR 319 -0.4048895 -1.693911 0.0000032 0.0000481 0.0000383 4096 RAD51B/H2BC4/H2BC5/TERF1/PNKP/CCNH/PIAS3/BRCA2/PPIE/OGG1/KDM4A/FANCL/REV3L/FANCE/NSD2/ERCC4/POLD3/RFC5/RPA3/RUVBL1/APBB1/USP45/SPRTN/MSH6/BARD1/MSH2/TIMELESS/RPS27A/H4C3/POT1/ATRIP/FEN1/ATM/LIG1/RAD9B/ATR/H4C2/H2AX/H2AZ2/UBE2T/POLR2I/MRE11/POLH/WRN/GTF2H5/RAD52/H2BC6/RAD9A/RMI1/H4C6/DDB2/NTHL1/MSH3/LIG3/POLI/H2BC15/H2BC9/NEIL1/MGMT/FANCM/H4C12/ERCC1/RFC3/H2BC12/ABRAXAS1/H4C4/XRCC3/BRCA1/POLN/CETN2/EME1/RMI2/FANCI/POLD1/PCLAF/H2BC11/BRIP1/FANCB/MUTYH/H2BC3/H4C13/H2AC14/BLM/H2BC7/FTO/CCNA2/DNA2/RAD51/XRCC2/H2AC4/RAD51AP1/CLSPN/CHD1L/H2BC10/H4C1/POLQ/H4C9/EXO1/H2BC17/NEIL3/POLE2/H2BC13/DTL/H2BC14
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 130 -0.5067771 -1.876992 0.0000032 0.0000486 0.0000386 1250 H3C1/KIF21A/RACGAP1/H3C13/H3C10/MYB/KIF11/GATA2/TUBB8B/KIF18A/KIF23/KIF20B/H3C7/KIF15/HBB/CENPE/KIF20A/KIF4A/H3C12/KIF2C/KIFC1/H3C3/H3C8/KIF18B/H3C2
REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES 65 -0.6217848 -2.079779 0.0000033 0.0000491 0.0000391 1250 H3C11/H4C12/SMYD2/H4C4/H3C1/H3C13/H3C10/EZH2/H4C13/H4C1/H3C7/H4C9/H3C12/H3C3/H3C8/H3C2
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 29 -0.7565257 -2.143315 0.0000040 0.0000587 0.0000467 1115 FBXO5/DHFR/ORC1/CCNE1/E2F1/CDC25A/TYMS/CDT1/CDK1/TK1/RRM2/CDC45
REACTOME_TELOMERE_MAINTENANCE 100 -0.5521465 -1.981909 0.0000048 0.0000691 0.0000549 3694 POLD3/RFC5/RPA3/RUVBL1/H4C3/POT1/SHQ1/FEN1/LIG1/H4C2/H2AX/H2AZ2/POLR2I/WRN/H2BC6/H4C6/H2BC15/H2BC9/RUVBL2/H3-3A/WRAP53/H4C12/RFC3/H2BC12/H4C4/DSCC1/POLD1/H2BC11/H2BC3/H4C13/H2AC14/BLM/H2BC7/CCNA2/DNA2/H2AC4/H2BC10/H4C1/H4C9/H2BC17/H2BC13/H2BC14
REACTOME_BASE_EXCISION_REPAIR_AP_SITE_FORMATION 53 -0.6523269 -2.132416 0.0000061 0.0000880 0.0000700 3362 H4C3/POT1/H4C2/H2AX/H2AZ2/H2BC6/H4C6/NTHL1/H2BC15/H2BC9/NEIL1/H4C12/H2BC12/H4C4/H2BC11/MUTYH/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H4C9/H2BC17/NEIL3/H2BC13/H2BC14
REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS 16 -0.8620329 -2.138759 0.0000070 0.0000997 0.0000793 720 CCNB1/CDC25C/CDC25A/CENPF/FOXM1/PLK1/CCNB2/MYBL2
REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE 46 -0.6770852 -2.127540 0.0000075 0.0001050 0.0000835 879 H4C3/POT1/H4C2/H2AX/H2AZ2/H2BC6/H4C6/H2BC15/H2BC9/H4C12/H2BC12/H4C4/H2BC11/MUTYH/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H4C9/H2BC17/NEIL3/H2BC13/H2BC14
REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS 85 -0.5601243 -1.966309 0.0000089 0.0001224 0.0000973 1115 FBXO5/ANAPC4/AURKA/CCNB1/CCNA2/PTTG1/MAD2L1/CDK1/PLK1/NEK2/CDC20/BUB1B/UBE2C
REACTOME_NEUTROPHIL_DEGRANULATION 392 0.4005638 1.597652 0.0000093 0.0001267 0.0001007 3821 S100A7/TNFAIP6/ACLY/FGL2/PRSS3/ALDOC/S100A12/PLAUR/FCGR2A/ITGAM/RAB24/S100P/SELL/SLCO4C1/MMP25/SERPINB12/BST2/SERPINA3/HP/CXCL1/CHRNB4/PLAU/SLC2A3/CEACAM1/CD177/OLFM4/PECAM1/ADAM8/HVCN1/TMBIM1/S100A8/TIMP2/CEACAM6/TNFRSF1B/CD55/VNN1/NEU1/HSPA6/IDH1/UNC13D/CD47/RAP2B/STK10/CKAP4/TLR2/RAB5B/PTAFR/VCL/CDA/RHOF/PTPRJ/S100A9/TSPAN14/CSTB/NPC2/PDXK/CSNK2B/LRRC7/LCN2/HLA-C/LPCAT1/GLIPR1/RAB4B/HGSNAT/STBD1/OLR1/ARL8A/RHOG/ARSB/VAT1/MOSPD2/ITGAV/PTGES2/PNP/ATP11A/HLA-B/RAB6A/CAP1/STOM/MGST1/HEXB/SURF4/DSN1/COTL1/PSMD11/RAB27A/NRAS/LRG1/TMC6/GYG1/GHDC/DGAT1/TUBB/CNN2/DIAPH1/CTSC/NFKB1/PPIA/TMEM63A/C3/ACAA1/SLC15A4/MGAM/JUP/ARSA/HLA-A/PLEKHO2/SIRPA/VCP/AP1M1/ALDOA/DNAJC13/RAP2C/HMOX2/MANBA/QPCT/PGRMC1/ATAD3B/IQGAP1/TMEM30A/MAGT1/HEBP2/IMPDH1/PSMD1/CD63/APEH/FRK/ALOX5/ITGAL/PSMD7/SLC44A2/RHOA/RAC1/NBEAL2/DYNC1H1/B4GALT1/CANT1/SERPINA1
REACTOME_PHOSPHORYLATION_OF_THE_APC_C 20 -0.8036911 -2.134205 0.0000123 0.0001655 0.0001316 861 ANAPC4/CCNB1/CDK1/PLK1/UBE2C
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1 207 -0.4344358 -1.739622 0.0000165 0.0002196 0.0001746 1108 H3C13/H3C10/CTSK/H2BC11/MYB/CBX2/H2BC3/GATA2/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/CSF2/H3C7/H4C9/CLDN5/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT 201 -0.4411588 -1.761914 0.0000196 0.0002590 0.0002060 1331 SOX13/CBY1/ZNRF3/TLE3/H2BC15/H2BC9/SOX2/FRAT2/H3-3A/H3C11/H4C12/H2BC12/H4C4/TCF7/AXIN2/H3C1/H3C13/LEF1/H3C10/H2BC11/H2BC3/WNT3A/H4C13/CXXC4/WIF1/H2AC14/H2BC7/H2AC4/LGR6/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_G0_AND_EARLY_G1 27 -0.7580607 -2.126988 0.0000221 0.0002885 0.0002294 821 CCNE1/E2F1/CCNA2/CDC25A/CCNE2/CDK1/TOP2A/MYBL2
REACTOME_EUKARYOTIC_TRANSLATION_INITIATION 117 -0.5108012 -1.853715 0.0000246 0.0003167 0.0002519 4726 RPL12/EIF3H/RPL10/RPS11/RPS26/RPL18/RPS16/RPL18A/RPS24/RPL23A/RPL24/EIF4A2/RPS5/RPS27/RPS12/RPL27/EIF3D/RPL9/EIF3L/RPS8/RPL7A/EIF3F/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/RPL41/RPL27A/RPL37A/RPL34/RPS15A/RPS28/PABPC1/RPS29/RPL3/RPS2/RPS20/RPS13/RPS4Y1/RPL29/RPS23/RPL11/RPS25/RPL4/RPL30/RPL21/RPL23/RPL31/RPL13A/RPL32/RPL35A/RPL26L1/RPS6/RPSA/RPS4X/RPL15/RPS7/RPL6/RPL37/RPS18/EIF3E/RPL22/EIF4B/RPS14/RPL7/RPL5/RPL10A/RPS3A/RPS10/RPL39L
REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS 254 -0.3971720 -1.635569 0.0000379 0.0004837 0.0003846 2098 H3C11/HSP90AA1/ARL4C/PIK3R1/H4C12/TNRC6C/PDK4/H2BC12/H4C4/NR1H3/NR5A2/GNGT1/APOE/PLIN1/H3C1/AKR1C3/RDH5/EEPD1/H3C13/H3C10/ADH1C/H2BC11/MYB/H2BC3/PLTP/H4C13/H2AC14/H2BC7/ALDH1A1/SREBF1/H2AC4/H2BC10/FABP5/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/ABCA1/MYLIP/ABCG1/H3C3/H2BC14/CYP26A1/H3C8/H3C2
REACTOME_MEIOTIC_SYNAPSIS 62 -0.5818364 -1.930450 0.0000487 0.0006144 0.0004885 3362 H4C3/POT1/ATR/H4C2/H2AX/H2AZ2/H2BC6/H4C6/SYNE1/H2BC15/H2BC9/H4C12/H2BC12/H4C4/BRCA1/SYCP2/H2BC11/H2BC3/H4C13/H2AC14/LMNB1/H2BC7/H2AC4/H2BC10/H4C1/H4C9/H2BC17/H2BC13/H2BC14
REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE 58 -0.6117005 -2.031656 0.0000562 0.0007021 0.0005583 3362 H4C3/POT1/H4C2/H2AX/H2AZ2/POLR2I/H2BC6/H4C6/H2BC15/H2BC9/H3-3A/H4C12/H2BC12/H4C4/H2BC11/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H4C9/H2BC17/H2BC13/H2BC14
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B 24 -0.7530019 -2.078724 0.0000569 0.0007024 0.0005585 861 ANAPC4/CCNB1/CDK1/CDC20/UBE2C
REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE 95 -0.5111712 -1.820956 0.0000652 0.0007974 0.0006340 4054 AHI1/TTBK2/HAUS3/IQCB1/ALMS1/TMEM216/DYNLL1/CEP41/CEP250/HAUS4/CEP76/TCTN2/CEP135/SFI1/HAUS1/B9D1/CEP57/CEP43/TCTN1/MKS1/CEP290/KIF24/CEP162/HAUS5/CEP97/CEP164/NPHP1/TUBB4B/CNTRL/RPGRIP1L/B9D2/AKAP9/HSP90AA1/PCM1/CC2D2A/TMEM67/CCP110/CEP83/CENPJ/CEP152/CETN2/FBF1/CEP78/CDK1/PLK1/NEK2/PLK4
REACTOME_SIGNALING_BY_INTERLEUKINS 375 0.3980414 1.582370 0.0000745 0.0009010 0.0007164 3188 CXCL10/IL19/CCL22/EBI3/IL36G/CCL4/CCL20/S100A12/IL32/CXCL2/CXCL8/FGF2/IL17C/LIF/ITGAM/IL2RG/IL1R2/CCL5/CLCF1/LBP/IL1RL1/IL1B/VCAM1/CXCL1/IL23A/PTGS2/SOCS2/IRAK2/CSF3/FYN/NFKB2/IL31RA/FOS/SERPINB2/MYD88/IL1RN/IL1A/SOCS1/IL1RL2/TNF/STX3/TNFRSF1B/VEGFA/STAT1/NFKBIA/NOS2/MAPK11/PSME4/JUN/BATF/SOCS3/IKBKG/LGALS9/SAA1/OSMR/IL18R1/MEF2C/PTAFR/ICAM1/TNIP2/DUSP6/CDKN1A/IL11/LCP1/MSN/IRAK3/PSMA6/DUSP3/MYC/IL34/IL36A/CSF1/STX4/LYN/IRS2/PIM1/LCN2/IL15RA/GAB2/IFNLR1/STAT2/NOD2/PELI1/PTPN12/IL7R/IRAK1/MAP3K8/VIM/ZEB1/MAPK3/ANXA1/PTPN2/SYK/STX1A/TALDO1/MAPK7/TAB3/SQSTM1/RALA/HMOX1/RIPK2/STAT5A/PTPN18/NOD1/IL13RA1/IL4R/PSMB9/PSMD11/TYK2/MAP2K1/DUSP4/CNN2/JUNB/CD86/IL15/PTPN9/IL1R1/MAP3K3/MAP2K3/NFKB1/NFKBIB/PPIA/SOS2/MUC1/IL18/CISH/IL10RB/UBC/CEBPD/P4HB/MAPKAPK2/NKIRAS2/PPP2R1B/PSME2/PTPN11/JAK1/MMP1/TWIST1/PSMC4/MAPKAPK3/RPS6KA3/CFL1
REACTOME_MYD88_INDEPENDENT_TLR4_CASCADE 95 0.5492536 1.847742 0.0000770 0.0009217 0.0007329 3178 S100A12/IRF7/BIRC3/IRAK2/NFKB2/FOS/RIPK3/TICAM1/NFKBIA/MAPK11/JUN/IKBKG/SAA1/IKBKE/LY96/MEF2C/TLR4/TNIP2/DUSP6/DUSP3/NOD2/IRAK1/MAP3K8/MAPK3/MAPK7/TAB3/RIPK2/NOD1/MAP2K1/DUSP4/MAP2K3/NFKB1/NFKBIB/UBC/MAPKAPK2/FADD/NKIRAS2/CASP8/PPP2R1B/PTPN11/MAPKAPK3/RPS6KA3
REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ 63 -0.5756476 -1.921980 0.0000901 0.0010677 0.0008490 3486 BARD1/H4C3/ATM/H4C2/H2AX/MRE11/H2BC6/H4C6/H2BC15/H2BC9/H4C12/H2BC12/ABRAXAS1/H4C4/BRCA1/H2BC11/H2BC3/H4C13/H2BC7/H2BC10/H4C1/H4C9/H2BC17/H2BC13/H2BC14
REACTOME_TOLL_LIKE_RECEPTOR_CASCADES 139 0.4915866 1.738911 0.0000921 0.0010798 0.0008586 3230 S100A12/ITGAM/LBP/IRF7/BIRC3/IRAK2/NFKB2/FOS/MYD88/SOCS1/S100A8/RIPK3/TICAM1/NFKBIA/MAPK11/JUN/IKBKG/SAA1/IKBKE/LY96/TLR2/MEF2C/TLR4/TNIP2/DUSP6/S100A9/IRAK3/DUSP3/LGMN/NOD2/PELI1/IRAK1/MAP3K8/MAPK3/CTSV/MAPK7/TAB3/RIPK2/NOD1/MAP2K1/DUSP4/MAP2K3/NFKB1/NFKBIB/UBC/MAPKAPK2/FADD/NKIRAS2/CASP8/PPP2R1B/TIRAP/PTPN11/MAPKAPK3/RPS6KA3/GSDME
REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA 66 0.5910041 1.892932 0.0000965 0.0011039 0.0008777 2975 ISG15/S100A12/NLRC5/IRF7/IFIH1/HERC5/NFKB2/CASP10/NFKBIA/IKBKG/SAA1/IKBKE/UBE2L6/TNFAIP3/DHX58/TRIM25/TRAF2/NFKB1/NFKBIB/UBC/FADD/NKIRAS2/CASP8
REACTOME_SIGNALING_BY_NTRKS 123 0.5066677 1.770212 0.0000970 0.0011039 0.0008777 3743 ARC/NTRK1/NTRK3/ASCL1/FOSB/FYN/EGR2/FOS/MAPK11/SGK1/PTPRO/MEF2C/JUND/DUSP6/DUSP3/TRIB1/IRS2/SHC2/ID4/SRF/MAPK3/ID3/AP2B1/NTRK2/FURIN/MAPK7/RALA/KRAS/SRC/FOSL1/NRAS/MAP2K1/EGR1/F3/DUSP4/JUNB/RIT1/ID1/MAPKAPK2/PPP2R1B/PLCG1/PTPN11/MAPKAPK3/RPS6KA3/MAP2K2/MAPK13/IRS1/SHC1/CRK/HRAS/MAPK12/RHOA/RAC1/RAPGEF1
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 175 0.4644928 1.709358 0.0000968 0.0011039 0.0008777 2945 SLC26A9/SLC18A2/SLC2A6/SLC29A2/SLC2A4/RHCG/SLC8A1/SLC39A8/SLC7A11/SLC5A1/SLCO4C1/SLC26A4/SLC5A8/SLC7A9/SLCO4A1/SLC6A11/SLC2A3/SLC26A6/SLCO1B1/SLC9A4/SLC6A14/SLC13A5/HEPH/SLC20A1/SLC15A3/SLC9A2/SLC16A3/SLC35C1/SLC10A6/SLC15A1/SLC9A3/SLC4A3/SLC3A2/SLC50A1/SLC2A12/SLC12A4/SLC7A7/SLC8B1/SLC28A1/SLC9A6/SLCO3A1/SLC11A2/SLC28A3/SLC1A4/SLC39A1/SLC5A5/SLC27A4/SLC5A12/SLC39A7/SLC7A1/SLC12A2/SLC7A5/SLC5A6/SLC9A7/SLC9A1/SLC39A4/SLC25A22/SLC31A1/SLC41A2/AHCYL2/CTNS/SLC36A1/SLC38A5/SLC15A4
REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING 126 0.5083084 1.771655 0.0001047 0.0011802 0.0009384 3817 IL36G/S100A12/IL1R2/IL1RL1/IL1B/IRAK2/NFKB2/MYD88/IL1RN/IL1A/IL1RL2/NFKBIA/PSME4/IKBKG/SAA1/IL18R1/TNIP2/IRAK3/PSMA6/IL36A/NOD2/PELI1/PTPN12/IRAK1/MAP3K8/PTPN2/TAB3/SQSTM1/RIPK2/PTPN18/NOD1/PSMB9/PSMD11/MAP2K1/PTPN9/IL1R1/MAP3K3/NFKB1/NFKBIB/IL18/UBC/NKIRAS2/PSME2/PTPN11/PSMC4/RELA/PSMD1/PSMA1/ALOX5/IL18BP/PSMD7/PSMB8/SMAD3
REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 80 0.5481913 1.803735 0.0001479 0.0016513 0.0013130 3495 MX2/ISG15/IFIT1/OAS3/OASL/OAS1/MX1/OAS2/HERC5/USP18/STAT1/UBE2L6/EIF2AK2/TRIM25/MAPK3/SEC13/FLNA/KPNA2/UBC/NEDD4/PLCG1/JAK1/EIF4A1/EIF4G1/NUP58/KPNA1
REACTOME_DISEASES_OF_DNA_REPAIR 34 -0.6713804 -1.969009 0.0001573 0.0017398 0.0013834 3490 RAD51B/BRCA2/OGG1/MSH6/BARD1/MSH2/ATM/MRE11/WRN/RMI1/NTHL1/MSH3/NEIL1/BRCA1/RMI2/BRIP1/MUTYH/BLM/DNA2/RAD51/XRCC2/RAD51AP1/EXO1/NEIL3
REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX 32 -0.6917515 -1.995914 0.0001829 0.0020037 0.0015932 1540 GMNN/CDC7/ORC6/ORC1/CDT1/POLE2/MCM10/CDC45
REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION 24 -0.7247637 -2.000770 0.0001856 0.0020139 0.0016013 720 PKMYT1/CCNB1/CDC25C/CCNA2/CDC25A/CDK1/FOXM1/PLK1/CCNB2
REACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE 90 0.5319528 1.785211 0.0002339 0.0025146 0.0019994 3178 S100A12/IRF7/IRAK2/NFKB2/FOS/MYD88/TICAM1/NFKBIA/MAPK11/JUN/IKBKG/SAA1/LY96/MEF2C/TLR4/TNIP2/DUSP6/DUSP3/NOD2/PELI1/IRAK1/MAP3K8/MAPK3/MAPK7/TAB3/RIPK2/NOD1/MAP2K1/DUSP4/MAP2K3/NFKB1/NFKBIB/UBC/MAPKAPK2/NKIRAS2/PPP2R1B/MAPKAPK3/RPS6KA3
REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES 446 0.3689054 1.485095 0.0002563 0.0027304 0.0021711 3281 ARC/NTRK1/FGFR4/FGFBP1/TRIB3/NTRK3/FGF2/NCF1/KDR/IL2RG/ASCL1/EREG/IGF2/FOSB/KLB/NCF2/THBS1/FYN/EGR2/COL6A3/FOS/SOCS1/AREG/VEGFA/LAMA3/STAT1/HBEGF/LAMC2/MAPK11/SGK1/ELMO1/FGF1/CD274/LAMB3/COL6A1/PRDM1/NCF4/PDGFB/PTPRO/FGFBP3/ITPR2/MEF2C/WASF1/SH2B3/JUND/DUSP6/COL9A2/PTPRJ/SPRY1/MKNK1/GRB10/DUSP3/MET/MYC/FLRT2/EGF/LYN/TRIB1/FLT1/ITGB3/COL5A3/IRS2/PTPRK/KL/SHC2/COL1A1/GAB2/ITPR3/SPHK1/RAB4B/ID4/PTPN12/AKT3/MST1R/PDGFC/SRF/TNS4/MAPK3/PTPN2/ID3/ITGAV/AP2B1/ADAM17/NTRK2/FURIN/MAPK7/RALA/LAMC1/BCAR1/ITGA3/KRAS/SRC/STAT5A/PTPN18/FOSL1/COL24A1/TGFA/SPINT1/ADAP1/NRAS/MAP2K1/EGR1/F3/NRG1/DUSP4/JUNB/ACTB/DIAPH1/NCK1/RIT1/ACTG1/POLR2G/ID1/UBC/MAPKAPK2/NEDD4/PPP2R1B/ATP6V1E2/JUP/SPRED2/PLCG1/SHB/SPARC/PTPN11/MAPKAPK3/GTF2F2/SH3KBP1/RPS6KA3/CAV1/MAP2K2/ELMO2/THBS4/GRB7
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 110 -0.4748945 -1.716568 0.0002588 0.0027312 0.0021717 4457 RPS11/RPS26/RPL18/RPS16/RPL18A/RPS24/RPL23A/SEC61A2/RPL24/RPS5/RPS27/RPS12/RPL27/RPL9/RPS8/RPL7A/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/RPL41/RPL27A/RPL37A/RPL34/RPS15A/RPS28/SRP9/RPS29/RPL3/RPS2/RPS20/RPS13/RPS4Y1/RPL29/RPS23/RPL11/RPS25/RPL4/RPL30/RPL21/RPL23/RPL31/RPL13A/RPL32/RPL35A/RPL26L1/RPS6/RPSA/RPS4X/RPL15/RPS7/RPL6/RPL37/RPS18/RPL22/RPS14/RPL7/RPL5/RPL10A/RPS3A/RPS10/RPL39L
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 65 0.5761577 1.839128 0.0002803 0.0029314 0.0023309 2336 LUM/ITGAM/KDR/COL13A1/ITGA9/VCAM1/THBS1/PECAM1/COL6A3/VWF/ITGA10/CD47/COL6A1/ICAM1/COL9A2/ITGB8/ITGB3/COL5A3/COL1A1/HSPG2/ITGB7/COL8A2/ITGAV/ITGB6/COL16A1/ITGA3
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 62 0.5849400 1.856641 0.0002876 0.0029813 0.0023706 998 CXCL10/CXCL11/CCL22/CCL4/CXCL9/CCL20/CCR3/CXCL2/CXCL6/CXCL3/CXCL8/CCL5/CXCL5/CXCL1/C5AR2/EDN1/UTS2B/GALR2/CX3CL1/CXCL16/SAA1
REACTOME_NONSENSE_MEDIATED_DECAY_NMD 113 -0.4890005 -1.768846 0.0002976 0.0030577 0.0024313 4726 RPL12/UPF2/RPL10/UPF1/RPS11/RPS26/RPL18/RPS16/RPL18A/RPS24/UPF3A/RPL23A/RPL24/RPS5/RPS27/RPS12/RPL27/RPL9/RPS8/RPL7A/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/RPL41/RPL27A/RPL37A/RPL34/RPS15A/RPS28/PABPC1/RPS29/RPL3/RPS2/RPS20/RPS13/RPS4Y1/RPL29/RPS23/RPL11/RPS25/RPL4/RPL30/RPL21/RPL23/RPL31/RPL13A/RPL32/RPL35A/RPL26L1/RPS6/RPSA/RPS4X/RPL15/RPS7/RPL6/RPL37/RPS18/RPL22/RPS14/RPL7/RPL5/RPL10A/RPS3A/RPS10/RPL39L
REACTOME_LDL_CLEARANCE 17 0.7687538 1.886306 0.0004121 0.0041244 0.0032795 2201 PCSK9/LDLR/NPC1/LIPA/NPC2/AP2B1/LSR
REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE 72 -0.5386470 -1.840062 0.0004090 0.0041244 0.0032795 3573 APBB1/BARD1/RPS27A/H4C3/ATM/H4C2/H2AX/MRE11/H2BC6/H4C6/H2BC15/H2BC9/H4C12/H2BC12/ABRAXAS1/H4C4/BRCA1/H2BC11/H2BC3/H4C13/H2BC7/H2BC10/H4C1/H4C9/H2BC17/H2BC13/H2BC14
REACTOME_SIGNALING_BY_WNT 283 -0.3659253 -1.512109 0.0004105 0.0041244 0.0032795 1497 CAMK2A/GNGT1/WNT16/TCF7/ITPR1/PDE6A/AXIN2/ROR1/H3C1/H3C13/LEF1/H3C10/H2BC11/H2BC3/WNT3A/H4C13/CXXC4/WIF1/H2AC14/H2BC7/H2AC4/LGR6/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_METALLOPROTEASE_DUBS 30 -0.6723336 -1.923869 0.0004210 0.0041637 0.0033107 1933 ABRAXAS1/STAMBPL1/BRCA1/H2AC15/H2AC21/H2AC14/H2AC16/H2AC4/H2AC13/H2AC11/H2AC12
REACTOME_PROTEIN_UBIQUITINATION 77 -0.5174296 -1.779797 0.0004232 0.0041637 0.0033107 1041 HLTF/H2BC11/H2BC3/H2BC7/H2BC10/H2BC17/H2BC13/UBE2C/H2BC14
REACTOME_KERATINIZATION 70 0.5513193 1.778804 0.0004737 0.0046212 0.0036745 1364 SPRR2E/SPRR2F/SPRR2A/SPRR1A/SPRR3/SPRR2D/KRT78/RPTN/KRT6B/KRT24/PI3/KRT23/PRSS8/KRT7/IVL/DSC2/KRT80/KRTAP2-3/KRT17/KRT40/KRT86/SPRR1B/KRT8
REACTOME_ESR_MEDIATED_SIGNALING 194 -0.4040032 -1.604627 0.0005221 0.0050514 0.0040166 2377 TLE3/H2BC15/H2BC9/TFF3/H3-3A/H3C11/HSP90AA1/PIK3R1/H4C12/TNRC6C/H2BC12/H4C4/NR5A2/GNGT1/H3C1/H3C13/H3C10/H2BC11/MYB/H2BC3/H4C13/H2AC14/H2BC7/H2AC4/H2BC10/H4C1/H3C7/H4C9/H3C12/H2BC17/H2BC13/H3C3/H2BC14/H3C8/H3C2
REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS 115 0.4810602 1.670780 0.0005284 0.0050698 0.0040312 2009 CXCL10/CXCL11/ADRA1A/CCL22/CCL4/CXCL9/CCL20/CCR3/CXCL2/CXCL6/CXCL3/CXCL8/OXER1/CCL5/LPAR5/CXCL5/CXCL1/CNR1/C5AR2/EDN1/UTS2B/GALR2/CX3CL1/CXCL16/GPR68/SAA1/GNRH1/ADRB2/PTAFR/ECE1/OPN3/NLN/LPAR2/CCL17/HCAR3/HTR4/HRH1/GPR37L1/ANXA1/F2RL1
REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_ZBP1 17 0.7606669 1.866463 0.0005345 0.0050864 0.0040444 938 ZBP1/NFKB2/MYD88/RIPK3/TICAM1/NFKBIA/IKBKG
REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE 20 -0.7358202 -1.953974 0.0006230 0.0057861 0.0046007 1442 CDC14A/ANAPC4/CDC20/UBE2C
REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA 37 -0.6250409 -1.855077 0.0006186 0.0057861 0.0046007 3720 ERCC4/RFC5/RPA3/BARD1/ATRIP/ATM/RAD9B/ATR/MRE11/WRN/RAD52/RAD9A/RMI1/ERCC1/RFC3/BRCA1/RMI2/BRIP1/BLM/DNA2/RAD51/EXO1
REACTOME_S_PHASE 160 -0.4184783 -1.602437 0.0006172 0.0057861 0.0046007 1211 ORC6/POLD1/GINS1/ANAPC4/ORC1/CCNE1/E2F1/CCNA2/DNA2/CDC25A/GINS2/CDT1/CCNE2/ESCO2/CDCA5/POLE2/CDC45/UBE2C
REACTOME_INTERLEUKIN_7_SIGNALING 29 -0.6488657 -1.838303 0.0006344 0.0058457 0.0046482 1250 H3C1/H3C13/H3C10/IL7/TSLP/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_CILIUM_ASSEMBLY 184 -0.4020773 -1.577674 0.0006455 0.0059010 0.0046921 3904 HAUS3/IFT22/TUBAL3/UNC119B/BBS12/ARL6/ARL13B/IQCB1/ALMS1/ARL3/TMEM216/WDR19/BBS4/DYNLL1/CEP41/BBIP1/CEP250/HAUS4/CEP76/TRAF3IP1/KIF17/TCTN2/IFT74/CEP135/DYNC2I1/SFI1/HAUS1/TCP1/BBS9/B9D1/CEP57/DYNLT5/DYNLT2B/IFT43/CEP43/TCTN1/MKS1/CEP290/BBS2/KIF24/DYNC2LI1/CEP162/IFT52/HAUS5/IFT122/IFT140/CEP97/CEP164/NPHP1/TUBB4B/IFT57/CNTRL/DYNLT2/RPGRIP1L/LZTFL1/B9D2/IFT27/AKAP9/HSP90AA1/WDR35/CLUAP1/PCM1/IFT88/CC2D2A/IFT81/TMEM67/CCP110/CEP83/IFT172/IFT80/CENPJ/CEP152/CETN2/DYNC2H1/FBF1/TTC21B/CEP78/DYNLRB2/CNGA4/TUBB8B/CDK1/PLK1/NEK2/PLK4
REACTOME_ZBP1_DAI_MEDIATED_INDUCTION_OF_TYPE_I_IFNS 20 0.7453390 1.890291 0.0006650 0.0059854 0.0047592 938 ZBP1/NFKB2/MYD88/RIPK3/TICAM1/NFKBIA/IKBKG
REACTOME_AURKA_ACTIVATION_BY_TPX2 70 -0.5168346 -1.755596 0.0006646 0.0059854 0.0047592 3416 DYNLL1/CEP41/CEP250/HAUS4/CEP76/CEP135/SFI1/HAUS1/CEP57/CEP43/CEP290/HAUS5/CEP164/TUBB4B/CNTRL/AKAP9/HSP90AA1/PCM1/CCP110/CENPJ/CEP152/CETN2/CEP78/AURKA/CDK1/PLK1/NEK2/PLK4/TPX2
REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE 42 -0.5944830 -1.823037 0.0006811 0.0060824 0.0048363 3628 RFC5/RPA3/BARD1/ATRIP/ATM/RAD9B/ATR/MRE11/WRN/RAD9A/RMI1/RFC3/XRCC3/BRCA1/RMI2/BRIP1/BLM/DNA2/RAD51/XRCC2/RAD51AP1/EXO1
REACTOME_SYNTHESIS_OF_DNA 118 -0.4494650 -1.637442 0.0007359 0.0065220 0.0051859 1211 ORC6/POLD1/GINS1/ANAPC4/ORC1/CCNE1/CCNA2/DNA2/GINS2/CDT1/CCNE2/POLE2/CDC45/UBE2C
REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS 392 0.3581083 1.428318 0.0007640 0.0067198 0.0053432 4597 FGFR4/BCL2A1/DLL4/NR4A1/FGF2/KDR/EREG/KLB/HDAC9/CLCN6/FYN/DKK1/PPP2R5B/DUSP8/VWF/AREG/STAT1/HBEGF/PSME4/FGF1/HDAC6/EIF2AK3/PDGFB/VCL/DUSP6/RNF213/CDKN1A/DUSP10/LMNA/MSN/PSMA6/MET/MYC/LMO7/EGF/TPM4/LYN/ITGB3/IRS2/PIM1/KL/PORCN/GAB2/PTPN12/RRBP1/MRAS/AKT3/RHOG/MAPK3/ADAM17/HDAC7/DUSP16/SQSTM1/KRAS/TGFBR1/SRC/STAT5A/PSMB9/TGFA/PSMD11/NRAS/MAP2K1/NRG1/JUNB/ACTB/CD86/STRN/CEBPB/ACTG1/MYH9/POLR2G/UBC/PPP2R1B/PSME2/SPRED2/PLCG1/PPFIBP1/PTPN11/TGFBR2/PSMC4/SEC31A/GTF2F2/VCP/FZD5/SYVN1/MAP2K2/OS9/IQGAP1/FGF5/AXIN1/ZC3HAV1/IRS1/TPM3/PDGFRA/PSMD1/SHC1/PSMA1/HRAS/APH1A/PSMD7/PPP1CB/RAC1/PPP2R5A/FZD8/ZC3HC1/PSMB8/RAC2/GSK3B/SMAD3/KLC1/FOXO6/MPRIP/MDM2/AGTRAP/DERL2/BCR/ARAF/QKI/PSMB2/AKT1/YES1/PPM1B/PPP2R5D/ERBB3/PSEN1/NCOR1/VAV1/AKT1S1/ARRB1/NCSTN/PSME1/SPTBN1/MAML1/RPS6KB2/DUSP7/TFG/WDCP/PIK3CB/POLR2L/ATG7/MYO18A/CSK/PIK3R3
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 96 0.5052404 1.702256 0.0008803 0.0076847 0.0061104 3083 GRB14/SDC3/L1CAM/ITGAM/SLC7A11/SELL/SLC7A9/TNFRSF10A/CEACAM1/CD177/PROCR/FYN/CEACAM5/PECAM1/PF4V1/ESAM/CEACAM6/CD47/SLC16A3/SLC3A2/LYN/PSG5/ITGB3/COL1A1/SELP/SLC7A7/OLR1/ATP1B1/ITGAV/TREM1/ITGA3/KRAS/SRC/SLC7A5/NRAS/PPIA/TNFRSF10B/EPCAM/ITGA6/PLCG1/ITGA5/PTPN11/MMP1/SIRPA
REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION 58 0.5793251 1.819856 0.0008900 0.0077114 0.0061316 2976 ARC/ASCL1/FOSB/EGR2/FOS/MAPK11/SGK1/MEF2C/JUND/DUSP6/DUSP3/TRIB1/ID4/SRF/MAPK3/ID3/MAPK7/FOSL1/EGR1/F3/DUSP4/JUNB/ID1/MAPKAPK2/PPP2R1B
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL 57 0.5792574 1.813660 0.0009482 0.0081541 0.0064837 3033 NCR3LG1/IFITM1/MICA/SELL/VCAM1/SH2D1B/CD34/MICB/RAET1E/ICAM1/ULBP1/HLA-G/KLRD1/HLA-F/PVR/ULBP3/CD200/HLA-C/COL1A1/CD40/HLA-E/ITGB7/HLA-B/TREM1/COL17A1/NECTIN2/NPDC1/C3/CDH1/HLA-A
REACTOME_TRANSCRIPTION_OF_E2F_TARGETS_UNDER_NEGATIVE_CONTROL_BY_P107_RBL1_AND_P130_RBL2_IN_COMPLEX_WITH_HDAC1 16 -0.7672494 -1.903595 0.0009732 0.0083078 0.0066059 734 E2F1/CCNA2/CDK1/MYBL2
REACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR 65 -0.5101115 -1.706248 0.0009867 0.0083618 0.0066488 3694 POLD3/RFC5/RPA3/BARD1/RPS27A/ATRIP/ATM/RAD9B/ATR/MRE11/POLH/WRN/RAD9A/RMI1/RFC3/XRCC3/BRCA1/EME1/RMI2/POLD1/BRIP1/BLM/DNA2/RAD51/XRCC2/RAD51AP1/EXO1/POLE2
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE 69 0.5470121 1.761088 0.0010781 0.0090692 0.0072113 1364 SPRR2E/SPRR2F/SPRR2A/SPRR1A/SPRR3/SPRR2D/KRT78/RPTN/KRT6B/KRT24/PI3/KRT23/PRSS8/KRT7/IVL/DSC2/KRT80/KRT17/KRT40/KRT86/SPRR1B/KRT8
REACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION 85 -0.4742442 -1.664828 0.0010858 0.0090692 0.0072113 3498 BORA/DYNLL1/RPS27A/CEP41/CEP250/HAUS4/CEP76/CEP135/SFI1/HAUS1/CEP57/CEP43/CEP290/HAUS5/CEP164/TUBB4B/CNTRL/AKAP9/HSP90AA1/PCM1/CCP110/CENPJ/CEP152/CETN2/CEP78/AURKA/CCNB1/CDK1/PLK1/NEK2/CCNB2/PLK4
REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING 34 0.6344609 1.788527 0.0011400 0.0094541 0.0075173 1070 ISG15/NLRC5/IFIH1/HERC5/IKBKE/UBE2L6/TNFAIP3
REACTOME_PLASMA_LIPOPROTEIN_CLEARANCE 29 0.6493643 1.767493 0.0011723 0.0096526 0.0076752 1023 APOC1/PCSK9/LIPC/LDLR/NPC1/SCARB1/LIPA/AMN/APOBR
REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK 87 0.5123516 1.706344 0.0012104 0.0098513 0.0078332 3804 FGFR4/TRIB3/FGF2/EREG/IL1RL1/KLB/FYN/PPP2R5B/MYD88/AREG/PHLPP2/IER3/HBEGF/FGF1/PDGFB/MET/EGF/IRS2/KL/GAB2/AKT3/IRAK1/RHOG/MAPK3/PIP4K2A/SRC/TGFA/NRG1/CD86/PIP4K2C/STRN/PPP2R1B/PTPN11/PIP4K2B/FGF5/IRS1/PDGFRA/RAC1/PPP2R5A/RAC2/PIP5K1A
REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE 96 0.4990060 1.681251 0.0012134 0.0098513 0.0078332 3178 S100A12/IRAK2/NFKB2/FOS/MYD88/SOCS1/S100A8/NFKBIA/MAPK11/JUN/IKBKG/SAA1/LY96/TLR2/MEF2C/TLR4/TNIP2/DUSP6/S100A9/IRAK3/DUSP3/NOD2/PELI1/IRAK1/MAP3K8/MAPK3/MAPK7/TAB3/RIPK2/NOD1/MAP2K1/DUSP4/MAP2K3/NFKB1/NFKBIB/UBC/MAPKAPK2/NKIRAS2/PPP2R1B/TIRAP/MAPKAPK3/RPS6KA3
REACTOME_INTERLEUKIN_1_SIGNALING 99 0.4948298 1.671531 0.0012219 0.0098513 0.0078332 3770 S100A12/IL1R2/IL1B/IRAK2/NFKB2/MYD88/IL1RN/IL1A/NFKBIA/PSME4/IKBKG/SAA1/TNIP2/IRAK3/PSMA6/NOD2/PELI1/IRAK1/MAP3K8/TAB3/SQSTM1/RIPK2/NOD1/PSMB9/PSMD11/MAP2K1/IL1R1/MAP3K3/NFKB1/NFKBIB/UBC/NKIRAS2/PSME2/PSMC4/RELA/PSMD1/PSMA1/PSMD7/PSMB8
REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES 11 -0.8103034 -1.846479 0.0013056 0.0104541 0.0083125 720 SMC4/SMC2/CCNB1/CDK1/CCNB2/NCAPH/NCAPG
REACTOME_SELENOAMINO_ACID_METABOLISM 114 -0.4497014 -1.620538 0.0014202 0.0112938 0.0089802 4457 RPS11/RPS26/AIMP2/SEPSECS/RPL18/RPS16/RPL18A/RPS24/RPL23A/RPL24/RPS5/RPS27/RPS12/RPL27/RPL9/RPS8/RPL7A/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/RPL41/RPL27A/RPL37A/RPL34/RPS15A/RPS28/RPS29/RPL3/RPS2/RPS20/RPS13/RPS4Y1/RPL29/RPS23/RPL11/RPS25/NNMT/RPL4/RPL30/RPL21/RPL23/RPL31/RPL13A/RPL32/RPL35A/RPL26L1/RPS6/RPSA/RPS4X/RPL15/RPS7/RPL6/RPL37/RPS18/RPL22/RPS14/RPL7/RPL5/PSTK/RPL10A/RPS3A/RPS10/RPL39L/GNMT/MAT1A
REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS 111 0.4670391 1.609455 0.0014504 0.0114555 0.0091087 1679 QPRT/PRSS3/FASN/SLC5A8/PANK3/NT5E/PANK1/MMAB/SLC2A3/PTGS2/NAMPT/ALDH1L2/PARP9/AMN/MTHFD2/VNN1/ACACA/MTHFR/TPK1/MTHFD1L/PARP14/ENPP1/PDXK/SLC52A2/SLC52A3
REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS 132 0.4564303 1.603032 0.0016030 0.0125749 0.0099988 4863 SGIP1/LDLR/SYT2/SYT1/EREG/AREG/HBEGF/TOR1B/RAB5B/ADRB2/SNX9/PACSIN1/DVL2/EGF/DAB2/CFTR/IL7R/AP2B1/ITSN1/TGFA/ITSN2/ARPC2/NECAP1/TFRC/ACTB/ACTG1/PIK3C2A/UBC/CLTB/SYNJ2/SH3KBP1/ARFGAP1/ARPC4/SH3GL1/WASL/CTTN/NECAP2/BIN1/PICALM/PACSIN2/SCARB2/PIP5K1C/ARPC5/TRIP10/UBQLN1/FNBP1L/ARRB1/GRK2/IGF2R/SYT11/FNBP1/AGFG1/STON2/RAB5A/FCHO2/SYNJ1/RAB5C/EPS15/CLTA/ARF6/OCRL/CBL/GRB2
REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS 31 0.6417807 1.780017 0.0016824 0.0129359 0.0102858 2172 ELOVL6/ACLY/SCD/FASN/ACSL1/HSD17B12/SLC25A1/ACSL4/ELOVL5/ELOVL7/ACACA/ELOVL1/HSD17B8/HACD2/ACSL5/ELOVL4
REACTOME_E3_UBIQUITIN_LIGASES_UBIQUITINATE_TARGET_PROTEINS 57 -0.5346153 -1.770096 0.0016819 0.0129359 0.0102858 1041 HLTF/H2BC11/H2BC3/H2BC7/H2BC10/H2BC17/H2BC13/H2BC14
REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY 15 0.7538507 1.761158 0.0016723 0.0129359 0.0102858 2699 TRIB3/CHAC1/ATF3/DDIT3/ATF5/ATF4/GRB10/CEBPG/CEBPB
REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS 13 -0.7819391 -1.825989 0.0017152 0.0131013 0.0104174 365 PDS5B/KIF23/PLK1/KIF20A
REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX 31 0.6399876 1.775044 0.0018427 0.0138918 0.0110460 2950 S100A12/IRAK2/NFKB2/NFKBIA/IKBKG/SAA1/NOD2/IRAK1/TAB3/RIPK2/NOD1/NFKB1/NFKBIB/UBC/NKIRAS2
REACTOME_GPCR_LIGAND_BINDING 182 0.4149020 1.534747 0.0018427 0.0138918 0.0110460 2009 CXCL10/CXCL11/ADRA1A/CCL22/CCL4/FZD9/CXCL9/CCL20/CCR3/CXCL2/CXCL6/CXCL3/CXCL8/OXER1/CCL5/LPAR5/CXCL5/CXCL1/ADM2/CNR1/C5AR2/GNG2/EDN1/UTS2B/GALR2/CX3CL1/TAS2R3/CXCL16/CD55/GPR68/UCN2/ADGRE2/GRM1/SAA1/GNRH1/ADRB2/PTAFR/ECE1/OPN3/WNT7A/NLN/LPAR2/CCL17/HCAR3/PTHLH/HTR4/GABBR1/HRH1/GPR37L1/ANXA1/F2RL1
REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY 87 0.5009022 1.668212 0.0018678 0.0139903 0.0111242 5664 TNFRSF9/CD70/TNFSF9/BIRC3/TNFRSF12A/NFKB2/RELB/TNFSF13B/TNFRSF13C/TNF/TNFRSF1B/PSME4/PSMA6/TNFSF14/CD40/TNFSF15/TRAF2/PSMB9/PSMD11/UBC/PSME2/PSMC4/TNFRSF1A/PSMD1/PSMA1/TNFRSF25/PSMD7/PSMB8/PSMB2/PSME1/EDA2R/MAP3K14/TNFSF11/PSMF1/TNFRSF18/PSMC1/PSMB6/PSMD14/LTBR/PSMD2/PSMA2/BTRC/CHUK/PSMA3/PSMC6/PSME3/PSMA7/TRAF3/PSMC5/PSMB7/PSMD8
REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 109 0.4757583 1.641053 0.0020009 0.0148911 0.0118405 1887 PLA2G3/PNPLA3/ACHE/LPIN1/PLA2G4C/GPCPD1/ABHD4/MFSD2A/PCYT2/SELENOI/TMEM86B/LIPH/PISD/GPAT3/PLAAT1/CSNK2B/LPCAT1/GPAT4/PLA2G15
REACTOME_BASIGIN_INTERACTIONS 20 0.7150459 1.813463 0.0020273 0.0149914 0.0119203 3181 L1CAM/SLC7A11/SLC7A9/SLC16A3/SLC3A2/SLC7A7/ATP1B1/ITGA3/SLC7A5/PPIA/ITGA6/MMP1/CAV1
REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS 62 0.5414841 1.718709 0.0024304 0.0178589 0.0142003 1311 LY6G6C/RAET1L/LY6K/PLAUR/CEACAM7/ALPL/NTNG1/CEACAM5/NTM/VNN1/MELTF/PIGW
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 79 -0.4721664 -1.635074 0.0025919 0.0189260 0.0150488 3416 CEP70/CEP131/CEP192/ODF2/MZT1/TUBGCP5/NME7/HAUS3/ALMS1/DYNLL1/MZT2A/TUBGCP2/CEP41/TUBG2/CEP250/HAUS4/CEP76/CEP135/SFI1/HAUS1/CEP57/CEP43/CEP290/HAUS5/CEP164/TUBB4B/CNTRL/AKAP9/HSP90AA1/PCM1/CCP110/CENPJ/CEP152/CETN2/CEP78/CDK1/PLK1/NEK2/PLK4
REACTOME_REGULATED_NECROSIS 53 0.5496303 1.681327 0.0028460 0.0206512 0.0164206 4587 TNFRSF10A/IL1B/BIRC3/IL1A/RIPK3/MLKL/CHMP7/PELI1/CHMP6/CASP5/TRAF2/FAS/BAK1/TRADD/IRF1/IL18/TNFRSF10B/UBC/FADD/CASP8/FLOT1/GSDME/CHMP4C/CFLAR/CHMP2B/TP53/SDCBP/RIPK1/CASP4/XIAP/CYCS/CHMP3
REACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM 11 0.8024523 1.715110 0.0029532 0.0212961 0.0169334 1348 FADS2/FADS1/ACSL1/ELOVL5/ELOVL1
REACTOME_FATTY_ACID_METABOLISM 145 0.4321925 1.542914 0.0031068 0.0222654 0.0177041 2196 FADS2/ELOVL6/FADS1/ACOT1/ACLY/SCD/FASN/ALOXE3/ACSL1/TBXAS1/HSD17B12/SLC25A1/ACSL4/ACOXL/PTGS2/ELOVL5/GGT5/ELOVL7/ACADL/ACACA/CYP4A22/PTGES/ELOVL1/ACOT2/CYP1B1/ACOT9/HSD17B8/ACOT7/HACD2/PTGES2/ACSL5/ELOVL4/ACAA2
REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC 25 0.6674605 1.782233 0.0034112 0.0242158 0.0192550 3960 TAP1/TAP2/HLA-G/HLA-F/SEC23A/HLA-C/HLA-E/SEC13/TAPBP/HLA-B/HLA-A/SEC31A/ERAP1/SEC24D/ERAP2/SEC24A/PDIA3/CALR
REACTOME_MITOTIC_G2_G2_M_PHASES 188 -0.3804710 -1.494569 0.0034207 0.0242158 0.0192550 791 AURKA/E2F1/CCNB1/TUBB8B/CDC25C/CCNA2/CDC25A/CENPF/CDK1/FOXM1/PLK1/NEK2/CCNB2/PLK4/TPX2/GTSE1/MYBL2
REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS 37 -0.5801482 -1.721838 0.0034984 0.0246163 0.0195734 3628 RFC5/RPA3/ATRIP/RAD9B/ATR/MCM4/RAD9A/RFC3/CDC7/ORC6/ORC1/CDC25C/CDC25A/CLSPN/MCM10/CDC45
REACTOME_SIGNALING_BY_GPCR 378 0.3399555 1.352963 0.0036230 0.0253393 0.0201483 2597 CXCL10/CXCL11/ADRA1A/RGS7/CCL22/CCL4/FZD9/CXCL9/CCL20/CCR3/RGS16/CXCL2/CXCL6/CXCL3/CXCL8/OXER1/CCL5/LPAR5/CXCL5/CXCL1/ADM2/PDE4C/GRK5/CNR1/C5AR2/GNG2/EDN1/UTS2B/CAMK4/DGKI/GALR2/CX3CL1/TAS2R3/RGS9/CXCL16/RHOB/CD55/RGS20/GPR68/HBEGF/UCN2/ADGRE2/GRM1/GNAZ/SAA1/FGD2/ITPR2/GNRH1/ADRB2/PTAFR/ECE1/PRKCQ/CAMKK1/ARHGEF9/TIAM2/GPR27/GNA15/ADCY4/MCF2L/OPN3/ADCY5/WNT7A/GNA12/NLN/NGEF/LPAR2/ITPR3/CCL17/CAMKK2/AKT3/HCAR3/PTHLH/ARHGEF40/HTR4/RGS10/GABBR1/HRH1/GPR37L1/MAPK3/ANXA1/F2RL1/TRIO/MAPK7/GPSM1/GABBR2/CCRL2/CCK/KRAS/SRC/ARHGEF1/ITSN1/RHOC/PRKCH/NRAS/ARHGEF37/KPNA2/PDE8A/PLCB3/ARHGEF3/P2RY2
REACTOME_CLEC7A_DECTIN_1_SIGNALING 98 0.4682328 1.575694 0.0037360 0.0259732 0.0206524 5664 CCL22/IL1B/NFKB2/RELB/CARD11/NFKBIA/PSME4/IKBKG/ITPR2/CLEC7A/PSMA6/ITPR3/CCL17/BCL10/SYK/TAB3/SRC/MALT1/PSMB9/PSMD11/NFKB1/UBC/CASP8/PSME2/PSMC4/CDC34/RELA/PSMD1/PSMA1/PSMD7/PSMB8/PSMB2/PSME1/MAP3K14/PSMF1/PSMC1/TAB2/PSMB6/PSMD14/PSMD2/PSMA2/BTRC/CHUK/PSMA3/PSMC6/PSME3/PSMA7/PPP3R1/PSMC5/PSMB7/PSMD8
REACTOME_NGF_STIMULATED_TRANSCRIPTION 36 0.6029570 1.720609 0.0038125 0.0263469 0.0209494 2841 ARC/ASCL1/FOSB/EGR2/FOS/SGK1/JUND/TRIB1/ID4/SRF/ID3/FOSL1/EGR1/F3/JUNB/ID1
REACTOME_INTERLEUKIN_17_SIGNALING 67 0.5176161 1.661008 0.0038900 0.0266981 0.0212287 3178 IL17C/IRAK2/FOS/MAPK11/JUN/IKBKG/MEF2C/TNIP2/DUSP6/DUSP3/NOD2/IRAK1/MAP3K8/MAPK3/MAPK7/TAB3/RIPK2/NOD1/MAP2K1/DUSP4/MAP2K3/NFKB1/UBC/MAPKAPK2/PPP2R1B/MAPKAPK3/RPS6KA3
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 171 0.4012393 1.471618 0.0039093 0.0266981 0.0212287 2001 CXCL10/CXCL11/RGS7/CCL4/CXCL9/CCL20/CCR3/RGS16/CXCL2/CXCL6/CXCL3/CXCL8/OXER1/CCL5/LPAR5/CXCL5/CXCL1/PDE4C/CNR1/GNG2/CAMK4/GALR2/CX3CL1/TAS2R3/RGS9/CXCL16/RGS20/GNAZ/SAA1/ITPR2/CAMKK1/GNA15/ADCY4/OPN3/ADCY5/LPAR2/ITPR3/CAMKK2/HCAR3/RGS10/GABBR1/GPR37L1/ANXA1
REACTOME_SIGNALLING_TO_ERKS 32 0.6298710 1.754992 0.0040396 0.0272675 0.0216815 3743 NTRK1/MAPK11/SHC2/MAPK3/RALA/KRAS/SRC/NRAS/MAP2K1/RIT1/MAPKAPK2/MAPKAPK3/MAP2K2/MAPK13/SHC1/CRK/HRAS/MAPK12/RAPGEF1
REACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING 11 0.7935098 1.695997 0.0040163 0.0272675 0.0216815 831 GGT7/CHAC1/GGT5/OPLAH
REACTOME_KINESINS 48 -0.5422692 -1.720909 0.0042037 0.0282109 0.0224316 1712 KIF19/KIF1A/KIF22/KIF21A/RACGAP1/KIF11/TUBB8B/KIF18A/KIF23/KIF20B/KIF15/CENPE/KIF20A/KIF4A/KIF2C/KIFC1/KIF18B
REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES 186 -0.3675168 -1.447250 0.0045331 0.0302469 0.0240506 1001 H2AC15/H2BC11/H2AC21/IL33/H2BC3/H2AC14/H2BC7/CCNA2/CDC25A/H2AC16/USP13/H2AC4/H2AC13/CLSPN/H2BC10/H2AC11/H2AC12/H2BC17/H2BC13/CDC20/H2BC14
REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY 42 0.5634768 1.651839 0.0048406 0.0321137 0.0255349 4174 DUSP5/PPP2R5B/DUSP8/DUSP6/DUSP10/DUSP1/MAPK3/DUSP16/KRAS/NRAS/MAP2K1/DUSP4/UBC/PPP2R1B/MAP2K2/HRAS/MAPK12/PPP2R5A/ARAF/PPP2R5D
REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING 117 0.4414470 1.533504 0.0049318 0.0325332 0.0258685 6056 LAT2/FYN/FOS/CARD11/NFKBIA/PSME4/JUN/IKBKG/ITPR2/PRKCQ/PSMA6/LYN/GAB2/ITPR3/BCL10/MAPK3/SYK/TAB3/KRAS/MALT1/PSMB9/PSMD11/NRAS/NFKB1/UBC/PSME2/PLCG1/PSMC4/CDC34/RELA/PSMD1/SHC1/PSMA1/HRAS/PSMD7/RAC1/PSMB8/TEC/VAV2/MAP2K7/PSMB2/VAV1/PSME1/PIK3CB/PIK3CA/PSMF1/PSMC1/TAB2/GRB2/PSMB6/PSMD14/PSMD2/PSMA2/BTRC/CHUK/PSMA3/PSMC6/PSME3/PSMA7/PAK2/PPP3R1/PSMC5/PSMB7/PSMD8/FBXW11/PSMD3/PSMD13/MAPK1/RASGRP1/MAPK9/PSMA4
REACTOME_INFLUENZA_INFECTION 153 -0.3821311 -1.451089 0.0051622 0.0338607 0.0269240 4595 RPL10/POLR2E/NUP85/RPS11/RPS26/RPL18/RPS16/NUP43/RPL18A/RPS24/RAE1/RPL23A/RPL24/RPS5/NUP107/RPS27/RPS12/RPL27/RPL9/RPS8/RPL7A/RPL14/RPS21/RPL13/RPS27A/RPL39/RPS19/RPL41/RPL27A/RPL37A/RPL34/NUP54/NUP155/RPS15A/RPS28/RPS29/RPL3/RPS2/RPS20/POLR2I/RPS13/RPS4Y1/RPL29/RPS23/RPL11/RPS25/RPL4/RPL30/RPL21/KPNA5/RPL23/RPL31/RPL13A/RPL32/RPL35A/HSPA1A/RPL26L1/RPS6/RPSA/RPS4X/RPL15/IPO5/RPS7/RPL6/NDC1/RPL37/RPS18/RPL22/RPS14/RPL7/RPL5/HSP90AA1/RPL10A/NUP37/RPS3A/RPS10/RPL39L
REACTOME_TRAF6_MEDIATED_NF_KB_ACTIVATION 23 0.6611885 1.728688 0.0053887 0.0345652 0.0274842 2950 S100A12/IFIH1/NFKB2/NFKBIA/IKBKG/SAA1/TRIM25/TRAF2/NFKB1/NFKBIB/NKIRAS2
REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS 45 -0.5353096 -1.662631 0.0053581 0.0345652 0.0274842 791 AURKA/CDCA8/TOP2A/BIRC5
REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC 87 -0.4402350 -1.543039 0.0053099 0.0345652 0.0274842 1712 KIF19/KIF1A/KIF22/KIF21A/RACGAP1/KIF11/TUBB8B/KIF18A/KIF23/KIF20B/KIF15/CENPE/KIF20A/KIF4A/KIF2C/KIFC1/KIF18B
REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA 105 0.4438214 1.513496 0.0053688 0.0345652 0.0274842 2568 HMGCS1/FADS1/HMGCR/FDFT1/TRIB3/ACSL1/ME1/HELZ2/ANGPTL4/ANKRD1/SREBF2/TIAM2/PPARGC1B/GLIPR1/PPARGC1A/ARNT2/MED8/TXNRD1/GPS2/MED31/SIN3B/AHR/GRHL1
REACTOME_SIGNALLING_TO_RAS 19 0.6696969 1.692786 0.0060857 0.0388216 0.0308687 3640 NTRK1/MAPK11/SHC2/RALA/KRAS/SRC/NRAS/MAPKAPK2/MAPKAPK3/MAPK13/SHC1/HRAS/MAPK12
REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX 104 0.4540274 1.548392 0.0063644 0.0403775 0.0321058 2327 CAPN14/MMP25/MMP16/MMP10/MMP17/COL13A1/CAPN12/ADAMTS5/COL6A3/ADAM8/KLK7/TIMP2/LAMA3/MMP19/LAMC2/LAMB3/COL6A1/MMP15/COL9A2/ADAMTS9/ADAM9/MMP7/MMP12/COL5A3/COL1A1/HSPG2/MMP13/COL8A2/CTSV/COL12A1/MMP24/ADAM17/FURIN/MMP14/CAPN13/COL25A1/ADAMTS1/COL16A1/LAMC1/COL17A1/CAPN2
REACTOME_SARS_COV_INFECTIONS 143 0.4112185 1.460410 0.0065459 0.0413035 0.0328421 3915 ZBP1/FXYD6/PARP9/VEGFA/IFNGR1/PARP14/FNTB/MGAT4C/SIGMAR1/CHMP7/ACE2/STAT2/CHMP6/PARP6/ATP1B1/AP2B1/FURIN/MGAT4A/ST3GAL1/TYK2/PARP10/TUBB/SRPK1/IL1R1/MGAT4B/UBC/MAP1LC3B/JAK1/PARP4/MGAT5/BRMS1/IFNGR2/VCP/EDEM2/PARP16/ST3GAL4/CHMP4C/MAGT1/IMPDH1/MAN2A1/STT3A/RPN2/GSK3B/ST3GAL2/CHMP2B
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6 34 -0.5670380 -1.662996 0.0067218 0.0419573 0.0333620 4808 PHC3/PCGF6/UXT/CBX5/CHEK1/BMI1/PHC1/EHMT2/YAF2/CBX3/TFDP1/EED/TFDP2/BRCA1/CDC7/EZH2/E2F1/RAD51/RRM2
REACTOME_PHOSPHOLIPID_METABOLISM 185 0.3949729 1.459876 0.0066969 0.0419573 0.0333620 4821 PLA2G3/PNPLA3/ACHE/LPIN1/PLA2G4C/GPCPD1/PIP4P1/ABHD4/MFSD2A/PCYT2/SELENOI/TMEM86B/ENPP6/LIPH/PI4K2A/PISD/GDPD3/GPAT3/PLAAT1/PLEKHA6/CSNK2B/LPCAT1/PIK3C2G/GPAT4/PLA2G15/PITPNB/PIP4K2A/PIK3C2B/INPP5F/LPIN2/DGAT1/PIP4K2C/PLB1/GPD2/LPCAT4/MBOAT7/PIK3C2A/ARF3/PNPLA2/PLA2G4A/SYNJ2/PITPNM2/PIP4K2B/PTDSS1/PNPLA8/PLEKHA2/TAFAZZIN/GDE1/SLC44A2/MGLL/PTDSS2/PIP5K1A/LPIN3/ABHD3/PIKFYVE/PIP5K1C/MTMR12/INPP4A/DDHD2/PEMT/MTMR14/PCYT1B/CRLS1/PLD2/PIK3CB/AGPAT3/RAB5A/PIK3R3/SBF2/PIK3CA/SYNJ1/PLEKHA1/PNPLA6/INPP5K/CPNE1/OCRL/STARD10
REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS 125 0.4396459 1.530882 0.0067728 0.0420496 0.0334353 3655 MUC21/CCL22/MUC3A/IL1B/FYN/NFKB2/RELB/CARD11/NFKBIA/PSME4/IKBKG/ITPR2/CLEC7A/PSMA6/LYN/ITPR3/CCL17/BCL10/SYK/TAB3/KRAS/SRC/MALT1/PSMB9/PSMD11/NRAS/NFKB1/MUC1/UBC/CASP8/PSME2/PSMC4/CDC34/RELA/PSMD1/PSMA1/HRAS/PSMD7
REACTOME_PI3K_AKT_SIGNALING_IN_CANCER 80 0.4690813 1.543437 0.0068191 0.0421117 0.0334847 4732 FGFR4/NR4A1/FGF2/EREG/KLB/FYN/AREG/HBEGF/FGF1/PDGFB/CDKN1A/MET/EGF/IRS2/KL/GAB2/AKT3/RHOG/SRC/TGFA/NRG1/CD86/STRN/PTPN11/FGF5/IRS1/PDGFRA/RAC1/RAC2/GSK3B/FOXO6/MDM2/AKT1/ERBB3/VAV1/AKT1S1/RPS6KB2/PIK3CB/PIK3R3/PIK3CA/ESR1
REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA 26 -0.6308442 -1.758023 0.0069388 0.0426239 0.0338920 1693 BARD1/ATM/MRE11/WRN/RMI1/XRCC3/BRCA1/RMI2/BRIP1/BLM/DNA2/RAD51/XRCC2/RAD51AP1/EXO1
REACTOME_TRYPTOPHAN_CATABOLISM 12 0.7421215 1.635818 0.0072773 0.0444684 0.0353586 1470 IDO1/IDO2/KYNU/KMO/SLC3A2/HAAO
REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION 11 -0.7560449 -1.722838 0.0075071 0.0456323 0.0362840 108 PDS5B/ESCO2/CDCA5
REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING 89 0.4646999 1.558249 0.0076459 0.0462335 0.0367621 3125 CCL22/CXCL8/FGF2/LIF/ITGAM/IL2RG/LBP/IL1B/VCAM1/IL23A/PTGS2/FOS/IL1A/SOCS1/TNF/TNFRSF1B/VEGFA/STAT1/NOS2/BATF/SOCS3/SAA1/ICAM1/CDKN1A/MYC/PIM1/LCN2/VIM/ZEB1/ANXA1/HMOX1/IL13RA1/IL4R/TYK2/JUNB/MUC1/IL18/CEBPD/JAK1/MMP1/TWIST1
REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING 24 0.6495137 1.716244 0.0079425 0.0477786 0.0379907 2445 EREG/FOS/AREG/HBEGF/EGF/AKT3/SRF/MAPK3/TGFA

Cytokine + Pitavastatin vs Control

Volcano plots

ensembl baseMean log2FoldChange lfcSE stat pvalue padj ensembl_version protID prot_name gene ENTREZID description gene_biotype
ENSG00000161905 24383.731220 3.086019 0.0760713 40.567465 0.0000000 0.0000000 ENSG00000161905.13 P16050 ALOX15 ALOX15 246 arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433] protein_coding
ENSG00000197632 8134.727375 2.949859 0.0769627 38.328442 0.0000000 0.0000000 ENSG00000197632.9 E7ERB5 SERPINB2 SERPINB2 5055 serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584] protein_coding
ENSG00000124215 5672.004630 3.733729 0.0585924 63.723767 0.0000000 0.0000000 ENSG00000124215.17 Q9NTY2 CDH26 CDH26 60437 cadherin 26 [Source:HGNC Symbol;Acc:HGNC:15902] protein_coding
ENSG00000188761 1324.570586 3.670520 0.0994891 36.893705 0.0000000 0.0000000 ENSG00000188761.13 Q5TBC7 BCL2L15 BCL2L15 440603 BCL2 like 15 [Source:HGNC Symbol;Acc:HGNC:33624] protein_coding
ENSG00000112972 7344.190156 2.449439 0.0692397 35.376229 0.0000000 0.0000000 ENSG00000112972.15 D6RIW1 HMGCS1 HMGCS1 3157 3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007] protein_coding
ENSG00000214711 1144.254049 6.661966 0.1893143 35.189985 0.0000000 0.0000000 ENSG00000214711.10 A8MX76 CAPN14 CAPN14 440854 calpain 14 [Source:HGNC Symbol;Acc:HGNC:16664] protein_coding
ENSG00000160752 2805.163978 2.205905 0.0635773 34.696411 0.0000000 0.0000000 ENSG00000160752.15 A0A087X1D8 FDPS FDPS 2224 farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631] protein_coding
ENSG00000140297 1379.857252 2.299425 0.0670620 34.288024 0.0000000 0.0000000 ENSG00000140297.13 A0A024R5T9 GCNT3 GCNT3 9245 glucosaminyl (N-acetyl) transferase 3, mucin type [Source:HGNC Symbol;Acc:HGNC:4205] protein_coding
ENSG00000138131 3844.508213 2.966518 0.0865512 34.274735 0.0000000 0.0000000 ENSG00000138131.4 Q96JB6 LOXL4 LOXL4 84171 lysyl oxidase like 4 [Source:HGNC Symbol;Acc:HGNC:17171] protein_coding
ENSG00000131620 731.106344 5.105899 0.1494284 34.169538 0.0000000 0.0000000 ENSG00000131620.18 E9PP68 ANO1 ANO1 55107 anoctamin 1 [Source:HGNC Symbol;Acc:HGNC:21625] protein_coding
ENSG00000206073 4195.872945 3.113437 0.0932904 33.373590 0.0000000 0.0000000 ENSG00000206073.11 P48594 SERPINB4 SERPINB4 6318 serpin family B member 4 [Source:HGNC Symbol;Acc:HGNC:10570] protein_coding
ENSG00000052802 7032.630916 1.951615 0.0608871 32.053027 0.0000000 0.0000000 ENSG00000052802.13 Q15800 MSMO1 MSMO1 6307 methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545] protein_coding
ENSG00000172575 654.800975 3.679468 0.1174177 31.336572 0.0000000 0.0000000 ENSG00000172575.14 H0YKP8 RASGRP1 RASGRP1 10125 RAS guanyl releasing protein 1 [Source:HGNC Symbol;Acc:HGNC:9878] protein_coding
ENSG00000186480 3171.726178 1.799258 0.0595423 30.218125 0.0000000 0.0000000 ENSG00000186480.13 C9JSG8 INSIG1 INSIG1 3638 insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083] protein_coding
ENSG00000120437 1559.403451 2.454426 0.0812328 30.214701 0.0000000 0.0000000 ENSG00000120437.9 Q9BWD1 ACAT2 ACAT2 39 acetyl-CoA acetyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:94] protein_coding
ENSG00000109861 7403.125064 1.970796 0.0659227 29.895555 0.0000000 0.0000000 ENSG00000109861.17 A0A7I2V3A6 CTSC CTSC 1075 cathepsin C [Source:HGNC Symbol;Acc:HGNC:2528] protein_coding
ENSG00000166348 3892.551650 1.755518 0.0587655 29.873297 0.0000000 0.0000000 ENSG00000166348.20 A0A8I5KRV2 USP54 USP54 159195 ubiquitin specific peptidase 54 [Source:HGNC Symbol;Acc:HGNC:23513] protein_coding
ENSG00000118515 2632.755859 1.984320 0.0675029 29.396084 0.0000000 0.0000000 ENSG00000118515.12 O00141 SGK1 SGK1 6446 serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810] protein_coding
ENSG00000167508 1108.457351 2.573266 0.0876140 29.370503 0.0000000 0.0000000 ENSG00000167508.12 H3BVC4 MVD MVD 4597 mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529] protein_coding
ENSG00000178934 799.404442 2.750897 0.0944480 29.126051 0.0000000 0.0000000 ENSG00000178934.5 P47929 LGALS7 LGALS7B 653499 galectin 7B [Source:HGNC Symbol;Acc:HGNC:34447] protein_coding
ENSG00000007171 1600.098037 6.587879 0.2289155 28.778644 0.0000000 0.0000000 ENSG00000007171.19 A0A8V8TKX9 NOS2 NOS2 4843 nitric oxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:7873] protein_coding
ENSG00000134824 2545.745645 2.252635 0.0785555 28.675705 0.0000000 0.0000000 ENSG00000134824.14 O95864 FADS2 FADS2 9415 fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575] protein_coding
ENSG00000140105 6108.437520 2.261892 0.0795675 28.427334 0.0000000 0.0000000 ENSG00000140105.18 G3V423 WARS1 WARS1 7453 tryptophanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12729] protein_coding
ENSG00000029153 2194.351473 1.596241 0.0570240 27.992426 0.0000000 0.0000000 ENSG00000029153.15 Q8WYA1 BMAL2 BMAL2 56938 basic helix-loop-helix ARNT like 2 [Source:HGNC Symbol;Acc:HGNC:18984] protein_coding
ENSG00000160285 2227.956667 2.197316 0.0786482 27.938533 0.0000000 0.0000000 ENSG00000160285.15 P48449 LSS LSS 4047 lanosterol synthase [Source:HGNC Symbol;Acc:HGNC:6708] protein_coding
ENSG00000164309 882.869631 3.005129 0.1097937 27.370677 0.0000000 0.0000000 ENSG00000164309.15 Q8N3K9 CMYA5 CMYA5 202333 cardiomyopathy associated 5 [Source:HGNC Symbol;Acc:HGNC:14305] protein_coding
ENSG00000197641 2089.207801 1.912026 0.0708166 26.999692 0.0000000 0.0000000 ENSG00000197641.12 Q9UIV8 SERPINB13 SERPINB13 5275 serpin family B member 13 [Source:HGNC Symbol;Acc:HGNC:8944] protein_coding
ENSG00000172893 1728.173460 2.038019 0.0776071 26.260730 0.0000000 0.0000000 ENSG00000172893.18 A0A804HL56 DHCR7 DHCR7 1717 7-dehydrocholesterol reductase [Source:HGNC Symbol;Acc:HGNC:2860] protein_coding
ENSG00000242550 1716.806799 2.463909 0.0950702 25.916729 0.0000000 0.0000000 ENSG00000242550.7 P48595 SERPINB10 SERPINB10 5273 serpin family B member 10 [Source:HGNC Symbol;Acc:HGNC:8942] protein_coding
ENSG00000196611 1161.479019 2.704531 0.1044448 25.894361 0.0000000 0.0000000 ENSG00000196611.6 P03956 MMP1 MMP1 4312 matrix metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:7155] protein_coding
ENSG00000198574 593.987947 6.692771 0.2618981 25.554869 0.0000000 0.0000000 ENSG00000198574.6 O14796 SH2D1B SH2D1B 117157 SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416] protein_coding
ENSG00000169908 2128.378006 1.619623 0.0635746 25.475942 0.0000000 0.0000000 ENSG00000169908.12 F8WF27 TM4SF1 TM4SF1 4071 transmembrane 4 L six family member 1 [Source:HGNC Symbol;Acc:HGNC:11853] protein_coding
ENSG00000174485 2299.262733 1.356718 0.0539516 25.146941 0.0000000 0.0000000 ENSG00000174485.16 H3BTW5 DENND4A DENND4A 10260 DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321] protein_coding
ENSG00000079459 5534.988758 1.450730 0.0577208 25.133595 0.0000000 0.0000000 ENSG00000079459.14 E9PSH1 FDFT1 FDFT1 2222 farnesyl-diphosphate farnesyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3629] protein_coding
ENSG00000136826 1576.393093 1.589856 0.0633820 25.083721 0.0000000 0.0000000 ENSG00000136826.15 A0A087X0S4 KLF4 KLF4 9314 KLF transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:6348] protein_coding
ENSG00000108244 3794.055122 1.775205 0.0719870 24.660071 0.0000000 0.0000000 ENSG00000108244.17 Q9C075 KRT23 KRT23 25984 keratin 23 [Source:HGNC Symbol;Acc:HGNC:6438] protein_coding
ENSG00000117143 2642.687344 1.730967 0.0712389 24.298052 0.0000000 0.0000000 ENSG00000117143.14 Q16222 UAP1 UAP1 6675 UDP-N-acetylglucosamine pyrophosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12457] protein_coding
ENSG00000135069 1207.885673 2.229770 0.0919938 24.238265 0.0000000 0.0000000 ENSG00000135069.14 Q9Y617 PSAT1 PSAT1 29968 phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:HGNC:19129] protein_coding
ENSG00000113161 5348.262899 1.833856 0.0765114 23.968385 0.0000000 0.0000000 ENSG00000113161.17 A0A7P0Z481 HMGCR HMGCR 3156 3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006] protein_coding
ENSG00000104549 3847.312430 1.328434 0.0557174 23.842354 0.0000000 0.0000000 ENSG00000104549.12 H0YBN7 SQLE SQLE 6713 squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279] protein_coding
ENSG00000189221 3303.326476 1.971650 0.0829892 23.757897 0.0000000 0.0000000 ENSG00000189221.11 P21397 MAOA MAOA 4128 monoamine oxidase A [Source:HGNC Symbol;Acc:HGNC:6833] protein_coding
ENSG00000268104 5939.325411 1.394170 0.0596007 23.391838 0.0000000 0.0000000 ENSG00000268104.3 Q9UN76 SLC6A14 SLC6A14 11254 solute carrier family 6 member 14 [Source:HGNC Symbol;Acc:HGNC:11047] protein_coding
ENSG00000186832 917.455341 2.234338 0.0959129 23.295475 0.0000000 0.0000000 ENSG00000186832.9 P08779 KRT16 KRT16 3868 keratin 16 [Source:HGNC Symbol;Acc:HGNC:6423] protein_coding
ENSG00000131069 1133.252872 1.885223 0.0810482 23.260509 0.0000000 0.0000000 ENSG00000131069.20 F8WC73 ACSS2 ACSS2 55902 acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814] protein_coding
ENSG00000168615 5544.163532 1.017412 0.0437835 23.237315 0.0000000 0.0000000 ENSG00000168615.13 A0A7I2V5N8 ADAM9 ADAM9 8754 ADAM metallopeptidase domain 9 [Source:HGNC Symbol;Acc:HGNC:216] protein_coding
ENSG00000170961 333.073004 4.226456 0.1853735 22.799680 0.0000000 0.0000000 ENSG00000170961.7 Q92819 HAS2 HAS2 3037 hyaluronan synthase 2 [Source:HGNC Symbol;Acc:HGNC:4819] protein_coding
ENSG00000170522 747.561613 2.197693 0.0967012 22.726626 0.0000000 0.0000000 ENSG00000170522.10 D6RBP4 ELOVL6 ELOVL6 79071 ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829] protein_coding
ENSG00000287059 565.582046 6.282832 0.2769701 22.684151 0.0000000 0.0000000 ENSG00000287059.1 NA novel transcript lncRNA
ENSG00000213626 1198.174106 1.557517 0.0692396 22.494585 0.0000000 0.0000000 ENSG00000213626.13 B5MCM2 LBH LBH 81606 LBH regulator of WNT signaling pathway [Source:HGNC Symbol;Acc:HGNC:29532] protein_coding
ENSG00000002587 1634.071113 2.046906 0.0921555 22.211432 0.0000000 0.0000000 ENSG00000002587.10 O14792 HS3ST1 HS3ST1 9957 heparan sulfate-glucosamine 3-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5194] protein_coding
ENSG00000156463 1128.091026 1.710631 0.0790951 21.627515 0.0000000 0.0000000 ENSG00000156463.18 Q8TEC5 SH3RF2 SH3RF2 153769 SH3 domain containing ring finger 2 [Source:HGNC Symbol;Acc:HGNC:26299] protein_coding
ENSG00000173559 669.534552 2.497139 0.1160169 21.523920 0.0000000 0.0000000 ENSG00000173559.15 Q96AH0 NABP1 NABP1 64859 nucleic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:26232] protein_coding
ENSG00000109084 671.850433 2.393237 0.1118336 21.399985 0.0000000 0.0000000 ENSG00000109084.14 J3KT68 TMEM97 TMEM97 27346 transmembrane protein 97 [Source:HGNC Symbol;Acc:HGNC:28106] protein_coding
ENSG00000075673 4771.572999 3.288860 0.1539368 21.364996 0.0000000 0.0000000 ENSG00000075673.12 P54707 ATP12A ATP12A 479 ATPase H+/K+ transporting non-gastric alpha2 subunit [Source:HGNC Symbol;Acc:HGNC:13816] protein_coding
ENSG00000138821 432.396839 2.564452 0.1206254 21.259629 0.0000000 0.0000000 ENSG00000138821.14 Q9C0K1 SLC39A8 SLC39A8 64116 solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] protein_coding
ENSG00000048028 1123.127543 1.574752 0.0743578 21.178026 0.0000000 0.0000000 ENSG00000048028.12 G3V1N5 USP28 USP28 57646 ubiquitin specific peptidase 28 [Source:HGNC Symbol;Acc:HGNC:12625] protein_coding
ENSG00000012660 4940.983963 1.367557 0.0647387 21.124260 0.0000000 0.0000000 ENSG00000012660.14 Q9NYP7 ELOVL5 ELOVL5 60481 ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308] protein_coding
ENSG00000137628 5951.247227 1.117327 0.0533995 20.923928 0.0000000 0.0000000 ENSG00000137628.18 A0A3G9HN97 DDX60 DDX60 55601 DExD/H-box helicase 60 [Source:HGNC Symbol;Acc:HGNC:25942] protein_coding
ENSG00000106105 1584.352773 1.610417 0.0772374 20.850221 0.0000000 0.0000000 ENSG00000106105.15 A0A6Q8PH49 GARS1 GARS1 2617 glycyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:4162] protein_coding
ENSG00000131711 5640.934424 1.600371 0.0777361 20.587225 0.0000000 0.0000000 ENSG00000131711.15 P46821 MAP1B MAP1B 4131 microtubule associated protein 1B [Source:HGNC Symbol;Acc:HGNC:6836] protein_coding
ENSG00000130164 6399.332792 1.521708 0.0741400 20.524798 0.0000000 0.0000000 ENSG00000130164.15 P01130 LDLR LDLR 3949 low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:6547] protein_coding
ENSG00000181577 311.753868 3.480508 0.1702445 20.444175 0.0000000 0.0000000 ENSG00000181577.16 LINC03040 221416 long intergenic non-protein coding RNA 3040 [Source:HGNC Symbol;Acc:HGNC:28692] lncRNA
ENSG00000065911 1001.183076 1.902084 0.0935050 20.342066 0.0000000 0.0000000 ENSG00000065911.13 A0A7I2V3T1 MTHFD2 MTHFD2 10797 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:7434] protein_coding
ENSG00000164211 1367.739722 1.504427 0.0745593 20.177586 0.0000000 0.0000000 ENSG00000164211.13 Q96DR4 STARD4 STARD4 134429 StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058] protein_coding
ENSG00000067064 6020.802801 1.596030 0.0794802 20.080851 0.0000000 0.0000000 ENSG00000067064.13 C9JD53 IDI1 IDI1 3422 isopentenyl-diphosphate delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:5387] protein_coding
ENSG00000120217 336.492845 2.976769 0.1485019 20.045334 0.0000000 0.0000000 ENSG00000120217.14 Q9NZQ7 CD274 CD274 29126 CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635] protein_coding
ENSG00000119917 1557.788127 1.457483 0.0727752 20.027199 0.0000000 0.0000000 ENSG00000119917.15 Q5T765 IFIT3 IFIT3 3437 interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] protein_coding
ENSG00000167600 2633.518094 1.366788 0.0682592 20.023488 0.0000000 0.0000000 ENSG00000167600.14 M0R057 CYP2S1 CYP2S1 29785 cytochrome P450 family 2 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:15654] protein_coding
ENSG00000128268 666.044381 2.099876 0.1053098 19.939973 0.0000000 0.0000000 ENSG00000128268.12 Q09327 MGAT3 MGAT3 4248 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7046] protein_coding
ENSG00000099994 229.080408 4.743828 0.2379214 19.938630 0.0000000 0.0000000 ENSG00000099994.11 A0A140VJW3 SUSD2 SUSD2 56241 sushi domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30667] protein_coding
ENSG00000151012 1268.876595 2.008317 0.1022641 19.638538 0.0000000 0.0000000 ENSG00000151012.13 H0Y9F9 SLC7A11 SLC7A11 23657 solute carrier family 7 member 11 [Source:HGNC Symbol;Acc:HGNC:11059] protein_coding
ENSG00000261040 1672.298952 1.610510 0.0822254 19.586518 0.0000000 0.0000000 ENSG00000261040.10 WFDC21P NA WAP four-disulfide core domain 21, pseudogene [Source:HGNC Symbol;Acc:HGNC:50357] transcribed_unitary_pseudogene
ENSG00000149485 1129.345081 1.530697 0.0784802 19.504250 0.0000000 0.0000000 ENSG00000149485.19 F5GWE3 FADS1 FADS1 3992 fatty acid desaturase 1 [Source:HGNC Symbol;Acc:HGNC:3574] protein_coding
ENSG00000073849 5043.999591 1.289900 0.0664026 19.425464 0.0000000 0.0000000 ENSG00000073849.16 C9K0R8 ST6GAL1 ST6GAL1 6480 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10860] protein_coding
ENSG00000119922 1029.786863 1.858783 0.0956884 19.425363 0.0000000 0.0000000 ENSG00000119922.11 P09913 IFIT2 IFIT2 3433 interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] protein_coding
ENSG00000196352 1254.146381 1.720524 0.0892248 19.283020 0.0000000 0.0000000 ENSG00000196352.18 B1AP13 CD55 CD55 1604 CD55 molecule (Cromer blood group) [Source:HGNC Symbol;Acc:HGNC:2665] protein_coding
ENSG00000109586 1791.773317 1.266936 0.0657429 19.271081 0.0000000 0.0000000 ENSG00000109586.12 H0YAH3 GALNT7 GALNT7 51809 polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129] protein_coding
ENSG00000138496 2366.725530 1.016889 0.0529214 19.215068 0.0000000 0.0000000 ENSG00000138496.17 Q8IXQ6 PARP9 PARP9 83666 poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118] protein_coding
ENSG00000064651 2849.855806 1.119433 0.0587942 19.039853 0.0000000 0.0000000 ENSG00000064651.14 P55011 SLC12A2 SLC12A2 6558 solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911] protein_coding
ENSG00000089127 1302.775685 1.384749 0.0729097 18.992642 0.0000000 0.0000000 ENSG00000089127.15 A0A7P0T960 OAS1 OAS1 4938 2’-5’-oligoadenylate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:8086] protein_coding
ENSG00000168389 1042.618103 1.405867 0.0744540 18.882362 0.0000000 0.0000000 ENSG00000168389.18 E7EPI8 MFSD2A MFSD2A 84879 MFSD2 lysolipid transporter A, lysophospholipid [Source:HGNC Symbol;Acc:HGNC:25897] protein_coding
ENSG00000233705 286.715205 3.033152 0.1608898 18.852355 0.0000000 0.0000000 ENSG00000233705.9 SLC26A4-AS1 NA SLC26A4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:22385] lncRNA
ENSG00000157601 2795.874836 1.353058 0.0722358 18.731124 0.0000000 0.0000000 ENSG00000157601.15 A0A7P0T9R0 MX1 MX1 4599 MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532] protein_coding
ENSG00000155846 710.759377 1.660043 0.0888314 18.687576 0.0000000 0.0000000 ENSG00000155846.17 Q86YN6 PPARGC1B PPARGC1B 133522 PPARG coactivator 1 beta [Source:HGNC Symbol;Acc:HGNC:30022] protein_coding
ENSG00000101445 493.884479 1.887603 0.1012854 18.636472 0.0000000 0.0000000 ENSG00000101445.10 Q96T49 PPP1R16B PPP1R16B 26051 protein phosphatase 1 regulatory subunit 16B [Source:HGNC Symbol;Acc:HGNC:15850] protein_coding
ENSG00000101670 511.513788 2.147427 0.1156872 18.562360 0.0000000 0.0000000 ENSG00000101670.12 J3KTN7 LIPG LIPG 9388 lipase G, endothelial type [Source:HGNC Symbol;Acc:HGNC:6623] protein_coding
ENSG00000131473 4168.904656 1.265970 0.0685799 18.459791 0.0000000 0.0000000 ENSG00000131473.17 P53396 ACLY ACLY 47 ATP citrate lyase [Source:HGNC Symbol;Acc:HGNC:115] protein_coding
ENSG00000248144 2144.760151 1.670999 0.0905464 18.454620 0.0000000 0.0000000 ENSG00000248144.6 P00326 ADH1C ADH1C 126 alcohol dehydrogenase 1C (class I), gamma polypeptide [Source:HGNC Symbol;Acc:HGNC:251] protein_coding
ENSG00000171492 860.882249 1.668341 0.0907584 18.382219 0.0000000 0.0000000 ENSG00000171492.14 E9PMF9 LRRC8D LRRC8D 55144 leucine rich repeat containing 8 VRAC subunit D [Source:HGNC Symbol;Acc:HGNC:16992] protein_coding
ENSG00000137440 1914.021781 1.553833 0.0846421 18.357688 0.0000000 0.0000000 ENSG00000137440.5 Q14512 FGFBP1 FGFBP1 9982 fibroblast growth factor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19695] protein_coding
ENSG00000170745 435.427653 2.210221 0.1212955 18.221788 0.0000000 0.0000000 ENSG00000170745.12 Q9BQ31 KCNS3 KCNS3 3790 potassium voltage-gated channel modifier subfamily S member 3 [Source:HGNC Symbol;Acc:HGNC:6302] protein_coding
ENSG00000137857 3042.573895 1.059504 0.0583455 18.159123 0.0000000 0.0000000 ENSG00000137857.18 Q9NRD9 DUOX1 DUOX1 53905 dual oxidase 1 [Source:HGNC Symbol;Acc:HGNC:3062] protein_coding
ENSG00000140254 896.901114 1.485455 0.0818469 18.149186 0.0000000 0.0000000 ENSG00000140254.13 H0YNR1 DUOXA1 DUOXA1 90527 dual oxidase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:26507] protein_coding
ENSG00000082641 7064.029006 1.140946 0.0636551 17.923880 0.0000000 0.0000000 ENSG00000082641.16 J3QQY8 NFE2L1 NFE2L1 4779 NFE2 like bZIP transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:7781] protein_coding
ENSG00000185338 183.695251 4.016713 0.2244476 17.895997 0.0000000 0.0000000 ENSG00000185338.7 O15524 SOCS1 SOCS1 8651 suppressor of cytokine signaling 1 [Source:HGNC Symbol;Acc:HGNC:19383] protein_coding
ENSG00000107863 3120.666501 1.132902 0.0635156 17.836595 0.0000000 0.0000000 ENSG00000107863.20 H0Y5T2 ARHGAP21 ARHGAP21 57584 Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:HGNC:23725] protein_coding
ENSG00000114737 262.742501 6.019670 0.3381901 17.799663 0.0000000 0.0000000 ENSG00000114737.16 Q9NSE2 CISH CISH 1154 cytokine inducible SH2 containing protein [Source:HGNC Symbol;Acc:HGNC:1984] protein_coding
ENSG00000103044 1493.467970 1.667025 0.0937077 17.789631 0.0000000 0.0000000 ENSG00000103044.11 H3BRH5 HAS3 HAS3 3038 hyaluronan synthase 3 [Source:HGNC Symbol;Acc:HGNC:4820] protein_coding
ENSG00000164038 412.905503 2.228950 0.1254961 17.761108 0.0000000 0.0000000 ENSG00000164038.16 Q86UD5 SLC9B2 SLC9B2 133308 solute carrier family 9 member B2 [Source:HGNC Symbol;Acc:HGNC:25143] protein_coding
ENSG00000183486 976.124436 1.809487 0.1023590 17.677846 0.0000000 0.0000000 ENSG00000183486.14 P20592 MX2 MX2 4600 MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533] protein_coding
ENSG00000057657 534.570659 1.850480 0.1047674 17.662750 0.0000000 0.0000000 ENSG00000057657.17 B2REA5 PRDM1 PRDM1 639 PR/SET domain 1 [Source:HGNC Symbol;Acc:HGNC:9346] protein_coding
ENSG00000148175 12068.978780 1.136524 0.0645258 17.613478 0.0000000 0.0000000 ENSG00000148175.13 P27105 STOM STOM 2040 stomatin [Source:HGNC Symbol;Acc:HGNC:3383] protein_coding
ENSG00000140022 4085.842729 1.078007 0.0612207 17.608544 0.0000000 0.0000000 ENSG00000140022.14 H0YJ05 STON2 STON2 85439 stonin 2 [Source:HGNC Symbol;Acc:HGNC:30652] protein_coding
ENSG00000133985 2660.389767 1.131548 0.0645156 17.539132 0.0000000 0.0000000 ENSG00000133985.3 Q92623 TTC9 TTC9 23508 tetratricopeptide repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20267] protein_coding
ENSG00000107959 1726.108926 1.301982 0.0745140 17.472979 0.0000000 0.0000000 ENSG00000107959.17 A0A7I2V3B6 PITRM1 PITRM1 10531 pitrilysin metallopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:17663] protein_coding
ENSG00000103942 1086.835530 1.346291 0.0770946 17.462831 0.0000000 0.0000000 ENSG00000103942.13 H0YNR9 HOMER2 HOMER2 9455 homer scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:17513] protein_coding
ENSG00000109929 3622.935134 1.193339 0.0684282 17.439284 0.0000000 0.0000000 ENSG00000109929.10 O75845 SC5D SC5D 6309 sterol-C5-desaturase [Source:HGNC Symbol;Acc:HGNC:10547] protein_coding
ENSG00000067082 2333.979576 1.308775 0.0751681 17.411309 0.0000000 0.0000000 ENSG00000067082.15 Q99612 KLF6 KLF6 1316 KLF transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:2235] protein_coding
ENSG00000104267 216.876412 3.837231 0.2214960 17.324153 0.0000000 0.0000000 ENSG00000104267.10 E5RK37 CA2 CA2 760 carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373] protein_coding
ENSG00000137449 705.361272 1.382224 0.0803968 17.192521 0.0000000 0.0000000 ENSG00000137449.17 A0A5K1VW79 CPEB2 CPEB2 132864 cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21745] protein_coding
ENSG00000113070 393.736708 2.087605 0.1217795 17.142499 0.0000000 0.0000000 ENSG00000113070.8 Q99075 HBEGF HBEGF 1839 heparin binding EGF like growth factor [Source:HGNC Symbol;Acc:HGNC:3059] protein_coding
ENSG00000159202 2692.203570 1.037141 0.0607799 17.063883 0.0000000 0.0000000 ENSG00000159202.18 Q9H832 UBE2Z UBE2Z 65264 ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847] protein_coding
ENSG00000074054 2438.868307 1.100694 0.0645165 17.060654 0.0000000 0.0000000 ENSG00000074054.21 C9J151 CLASP1 CLASP1 23332 cytoplasmic linker associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17088] protein_coding
ENSG00000197635 186.506933 4.058771 0.2393612 16.956677 0.0000000 0.0000000 ENSG00000197635.11 A0A7I2V2I2 DPP4 DPP4 1803 dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009] protein_coding
ENSG00000187608 483.891237 1.740575 0.1032161 16.863399 0.0000000 0.0000000 ENSG00000187608.10 P05161 ISG15 ISG15 9636 ISG15 ubiquitin like modifier [Source:HGNC Symbol;Acc:HGNC:4053] protein_coding
ENSG00000165474 2851.437944 1.661651 0.0987573 16.825602 0.0000000 0.0000000 ENSG00000165474.8 P29033 GJB2 GJB2 2706 gap junction protein beta 2 [Source:HGNC Symbol;Acc:HGNC:4284] protein_coding
ENSG00000134321 867.280605 1.751076 0.1048071 16.707605 0.0000000 0.0000000 ENSG00000134321.13 Q8WXG1 RSAD2 RSAD2 91543 radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908] protein_coding
ENSG00000165449 1094.288492 1.515261 0.0907605 16.695165 0.0000000 0.0000000 ENSG00000165449.12 Q7RTY1 SLC16A9 SLC16A9 220963 solute carrier family 16 member 9 [Source:HGNC Symbol;Acc:HGNC:23520] protein_coding
ENSG00000141458 1205.679848 1.415717 0.0850238 16.650843 0.0000000 0.0000000 ENSG00000141458.13 K7EIH7 NPC1 NPC1 4864 NPC intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7897] protein_coding
ENSG00000144824 836.207977 1.672902 0.1006398 16.622674 0.0000000 0.0000000 ENSG00000144824.21 A0A1W2PRT1 PHLDB2 PHLDB2 90102 pleckstrin homology like domain family B member 2 [Source:HGNC Symbol;Acc:HGNC:29573] protein_coding
ENSG00000196776 3188.665419 1.093067 0.0661875 16.514692 0.0000000 0.0000000 ENSG00000196776.17 A0A2R8Y484 CD47 CD47 961 CD47 molecule [Source:HGNC Symbol;Acc:HGNC:1682] protein_coding
ENSG00000165071 247.974337 2.545228 0.1542859 16.496828 0.0000000 0.0000000 ENSG00000165071.15 E5RGD3 TMEM71 TMEM71 137835 transmembrane protein 71 [Source:HGNC Symbol;Acc:HGNC:26572] protein_coding
ENSG00000128274 1550.139220 1.027231 0.0622874 16.491781 0.0000000 0.0000000 ENSG00000128274.17 Q9NPC4 A4GALT A4GALT 53947 alpha 1,4-galactosyltransferase (P blood group) [Source:HGNC Symbol;Acc:HGNC:18149] protein_coding
ENSG00000110090 1397.272635 1.053798 0.0639382 16.481500 0.0000000 0.0000000 ENSG00000110090.13 H3BUJ0 CPT1A CPT1A 1374 carnitine palmitoyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:2328] protein_coding
ENSG00000184254 4527.806349 1.504231 0.0914610 16.446690 0.0000000 0.0000000 ENSG00000184254.17 P47895 ALDH1A3 ALDH1A3 220 aldehyde dehydrogenase 1 family member A3 [Source:HGNC Symbol;Acc:HGNC:409] protein_coding
ENSG00000110799 167.758806 3.899815 0.2381605 16.374739 0.0000000 0.0000000 ENSG00000110799.14 P04275 VWF VWF 7450 von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726] protein_coding
ENSG00000137959 1438.165434 1.419142 0.0867893 16.351574 0.0000000 0.0000000 ENSG00000137959.17 H7C1K6 IFI44L IFI44L 10964 interferon induced protein 44 like [Source:HGNC Symbol;Acc:HGNC:17817] protein_coding
ENSG00000169174 349.057488 2.076702 0.1276044 16.274528 0.0000000 0.0000000 ENSG00000169174.12 A0A669KAY4 PCSK9 PCSK9 255738 proprotein convertase subtilisin/kexin type 9 [Source:HGNC Symbol;Acc:HGNC:20001] protein_coding
ENSG00000126016 1177.685773 1.224966 0.0755785 16.207869 0.0000000 0.0000000 ENSG00000126016.17 E7ERM3 AMOT AMOT 154796 angiomotin [Source:HGNC Symbol;Acc:HGNC:17810] protein_coding
ENSG00000100439 744.340141 1.231213 0.0763718 16.121313 0.0000000 0.0000000 ENSG00000100439.11 J3KMW0 ABHD4 ABHD4 63874 abhydrolase domain containing 4, N-acyl phospholipase B [Source:HGNC Symbol;Acc:HGNC:20154] protein_coding
ENSG00000173918 135.365666 3.921309 0.2439192 16.076262 0.0000000 0.0000000 ENSG00000173918.15 Q9BXJ1 C1QTNF1 C1QTNF1 114897 C1q and TNF related 1 [Source:HGNC Symbol;Acc:HGNC:14324] protein_coding
ENSG00000072786 552.126075 1.485326 0.0925444 16.049878 0.0000000 0.0000000 ENSG00000072786.13 O94804 STK10 STK10 6793 serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388] protein_coding
ENSG00000101255 212.168911 2.317335 0.1475157 15.709069 0.0000000 0.0000000 ENSG00000101255.12 J3KR25 TRIB3 TRIB3 57761 tribbles pseudokinase 3 [Source:HGNC Symbol;Acc:HGNC:16228] protein_coding
ENSG00000136869 234.212978 2.589162 0.1648973 15.701658 0.0000000 0.0000000 ENSG00000136869.16 O00206 TLR4 TLR4 7099 toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] protein_coding
ENSG00000134324 814.864521 1.429284 0.0910396 15.699584 0.0000000 0.0000000 ENSG00000134324.12 C9J278 LPIN1 LPIN1 23175 lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345] protein_coding
ENSG00000111331 2035.597144 1.605212 0.1022727 15.695410 0.0000000 0.0000000 ENSG00000111331.14 A0A7P0TAT5 OAS3 OAS3 4940 2’-5’-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088] protein_coding
ENSG00000100170 273.414767 2.575691 0.1642326 15.683187 0.0000000 0.0000000 ENSG00000100170.10 P13866 SLC5A1 SLC5A1 6523 solute carrier family 5 member 1 [Source:HGNC Symbol;Acc:HGNC:11036] protein_coding
ENSG00000154451 688.221074 1.522534 0.0973092 15.646363 0.0000000 0.0000000 ENSG00000154451.15 E7ETN8 GBP5 GBP5 115362 guanylate binding protein 5 [Source:HGNC Symbol;Acc:HGNC:19895] protein_coding
ENSG00000161921 1486.075585 1.218609 0.0786188 15.500223 0.0000000 0.0000000 ENSG00000161921.17 A0A6I8PIU7 CXCL16 CXCL16 58191 C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642] protein_coding
ENSG00000163898 1070.763510 1.116704 0.0723360 15.437743 0.0000000 0.0000000 ENSG00000163898.10 Q8WWY8 LIPH LIPH 200879 lipase H [Source:HGNC Symbol;Acc:HGNC:18483] protein_coding
ENSG00000099194 11321.691790 1.313261 0.0851747 15.418437 0.0000000 0.0000000 ENSG00000099194.6 O00767 SCD SCD 6319 stearoyl-CoA desaturase [Source:HGNC Symbol;Acc:HGNC:10571] protein_coding
ENSG00000150551 142.609152 3.267943 0.2125975 15.371505 0.0000000 0.0000000 ENSG00000150551.11 Q8N2G4 LYPD1 LYPD1 116372 LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28431] protein_coding
ENSG00000132205 113.001347 4.572478 0.3013313 15.174256 0.0000000 0.0000000 ENSG00000132205.11 Q9BXX0 EMILIN2 EMILIN2 84034 elastin microfibril interfacer 2 [Source:HGNC Symbol;Acc:HGNC:19881] protein_coding
ENSG00000050344 1050.228268 1.019438 0.0675075 15.101114 0.0000000 0.0000000 ENSG00000050344.9 Q9Y4A8 NFE2L3 NFE2L3 9603 NFE2 like bZIP transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:7783] protein_coding
ENSG00000130589 1046.715817 1.480834 0.0981093 15.093720 0.0000000 0.0000000 ENSG00000130589.16 Q9BYK8 HELZ2 HELZ2 85441 helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021] protein_coding
ENSG00000121207 449.607612 1.559180 0.1038779 15.009741 0.0000000 0.0000000 ENSG00000121207.12 O95237 LRAT LRAT 9227 lecithin retinol acyltransferase [Source:HGNC Symbol;Acc:HGNC:6685] protein_coding
ENSG00000050327 429.745430 1.517604 0.1019755 14.882042 0.0000000 0.0000000 ENSG00000050327.15 Q12774 ARHGEF5 ARHGEF5 7984 Rho guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:13209] protein_coding
ENSG00000011422 293.386498 1.794494 0.1211735 14.809286 0.0000000 0.0000000 ENSG00000011422.12 M0R0L1 PLAUR PLAUR 5329 plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053] protein_coding
ENSG00000134326 590.713492 1.430040 0.0969214 14.754637 0.0000000 0.0000000 ENSG00000134326.12 Q5EBM0 CMPK2 CMPK2 129607 cytidine/uridine monophosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:27015] protein_coding
ENSG00000155918 126.183936 3.296972 0.2236707 14.740295 0.0000000 0.0000000 ENSG00000155918.8 Q5VY80 RAET1L RAET1L 154064 retinoic acid early transcript 1L [Source:HGNC Symbol;Acc:HGNC:16798] protein_coding
ENSG00000221963 3196.329414 1.024299 0.0701279 14.606151 0.0000000 0.0000000 ENSG00000221963.6 Q9BWW8 APOL6 APOL6 80830 apolipoprotein L6 [Source:HGNC Symbol;Acc:HGNC:14870] protein_coding
ENSG00000188211 328.520462 1.703890 0.1167867 14.589752 0.0000000 0.0000000 ENSG00000188211.9 Q68D85 NCR3LG1 NCR3LG1 374383 natural killer cell cytotoxicity receptor 3 ligand 1 [Source:HGNC Symbol;Acc:HGNC:42400] protein_coding
ENSG00000135926 3168.518320 1.092747 0.0749568 14.578357 0.0000000 0.0000000 ENSG00000135926.15 Q969X1 TMBIM1 TMBIM1 64114 transmembrane BAX inhibitor motif containing 1 [Source:HGNC Symbol;Acc:HGNC:23410] protein_coding
ENSG00000108639 1410.453550 1.013296 0.0696787 14.542395 0.0000000 0.0000000 ENSG00000108639.8 K7ENG9 SYNGR2 SYNGR2 9144 synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499] protein_coding
ENSG00000138772 2062.877011 1.053040 0.0725979 14.505093 0.0000000 0.0000000 ENSG00000138772.13 D6RA82 ANXA3 ANXA3 306 annexin A3 [Source:HGNC Symbol;Acc:HGNC:541] protein_coding
ENSG00000185745 1436.956152 1.302865 0.0898451 14.501228 0.0000000 0.0000000 ENSG00000185745.10 P09914 IFIT1 IFIT1 3434 interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] protein_coding
ENSG00000265451 123.156143 4.178951 0.2885573 14.482220 0.0000000 0.0000000 ENSG00000265451.1 CLASP1-AS1 NA CLASP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:55328] lncRNA
ENSG00000169710 6760.843765 1.085491 0.0750988 14.454171 0.0000000 0.0000000 ENSG00000169710.9 A0A0U1RRG3 FASN FASN 2194 fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594] protein_coding
ENSG00000160211 1082.562130 1.082205 0.0748942 14.449772 0.0000000 0.0000000 ENSG00000160211.20 A0A8Q3SIS5 G6PD G6PD 2539 glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057] protein_coding
ENSG00000132196 336.397053 1.636209 0.1141551 14.333209 0.0000000 0.0000000 ENSG00000132196.16 F2Z2C2 HSD17B7 HSD17B7 51478 hydroxysteroid 17-beta dehydrogenase 7 [Source:HGNC Symbol;Acc:HGNC:5215] protein_coding
ENSG00000006606 2183.335634 11.978936 0.8366402 14.317907 0.0000000 0.0000000 ENSG00000006606.9 Q9Y258 CCL26 CCL26 10344 C-C motif chemokine ligand 26 [Source:HGNC Symbol;Acc:HGNC:10625] protein_coding
ENSG00000078725 137.724911 2.631835 0.1839049 14.310846 0.0000000 0.0000000 ENSG00000078725.13 O60477 BRINP1 BRINP1 1620 BMP/retinoic acid inducible neural specific 1 [Source:HGNC Symbol;Acc:HGNC:2687] protein_coding
ENSG00000169435 932.647270 1.044822 0.0742578 14.070204 0.0000000 0.0000000 ENSG00000169435.14 Q6ZTQ3 RASSF6 RASSF6 166824 Ras association domain family member 6 [Source:HGNC Symbol;Acc:HGNC:20796] protein_coding
ENSG00000070010 804.832706 1.040176 0.0742262 14.013596 0.0000000 0.0000000 ENSG00000070010.19 C9J7C8 UFD1 UFD1 7353 ubiquitin recognition factor in ER associated degradation 1 [Source:HGNC Symbol;Acc:HGNC:12520] protein_coding
ENSG00000224259 324.190925 1.586402 0.1133971 13.989796 0.0000000 0.0000000 ENSG00000224259.9 LINC01133 NA long intergenic non-protein coding RNA 1133 [Source:HGNC Symbol;Acc:HGNC:49447] lncRNA
ENSG00000125775 352.587729 1.772474 0.1268724 13.970520 0.0000000 0.0000000 ENSG00000125775.15 Q9H190 SDCBP2 SDCBP2 27111 syndecan binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15756] protein_coding
ENSG00000128965 206.442695 2.188523 0.1570125 13.938530 0.0000000 0.0000000 ENSG00000128965.13 Q9BUX1 CHAC1 CHAC1 79094 ChaC glutathione specific gamma-glutamylcyclotransferase 1 [Source:HGNC Symbol;Acc:HGNC:28680] protein_coding
ENSG00000178033 145.147927 3.187997 0.2290824 13.916381 0.0000000 0.0000000 ENSG00000178033.6 Q8N5C1 CALHM5 CALHM5 254228 calcium homeostasis modulator family member 5 [Source:HGNC Symbol;Acc:HGNC:21568] protein_coding
ENSG00000147383 550.094132 1.306490 0.0938848 13.915890 0.0000000 0.0000000 ENSG00000147383.11 Q15738 NSDHL NSDHL 50814 NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398] protein_coding
ENSG00000133935 2005.575618 1.008818 0.0726449 13.886965 0.0000000 0.0000000 ENSG00000133935.7 Q6FII3 C14orf1 ERG28 11161 ergosterol biosynthesis 28 homolog [Source:HGNC Symbol;Acc:HGNC:1187] protein_coding
ENSG00000065833 442.926257 1.465137 0.1058884 13.836615 0.0000000 0.0000000 ENSG00000065833.9 P48163 ME1 ME1 4199 malic enzyme 1 [Source:HGNC Symbol;Acc:HGNC:6983] protein_coding
ENSG00000124664 180.237854 2.447728 0.1775184 13.788586 0.0000000 0.0000000 ENSG00000124664.11 O95238 SPDEF SPDEF 25803 SAM pointed domain containing ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:17257] protein_coding
ENSG00000048052 2522.844613 1.221502 0.0886474 13.779339 0.0000000 0.0000000 ENSG00000048052.25 A0A7P0T8F4 HDAC9 HDAC9 9734 histone deacetylase 9 [Source:HGNC Symbol;Acc:HGNC:14065] protein_coding
ENSG00000168003 782.977029 1.195586 0.0871267 13.722375 0.0000000 0.0000000 ENSG00000168003.19 A0A7P0TAT7 SLC3A2 SLC3A2 6520 solute carrier family 3 member 2 [Source:HGNC Symbol;Acc:HGNC:11026] protein_coding
ENSG00000166986 1413.713955 1.192912 0.0871443 13.688936 0.0000000 0.0000000 ENSG00000166986.15 F8W0S4 MARS1 MARS1 4141 methionyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6898] protein_coding
ENSG00000113739 184.133204 2.202299 0.1615108 13.635617 0.0000000 0.0000000 ENSG00000113739.11 Q6FHC9 STC2 STC2 8614 stanniocalcin 2 [Source:HGNC Symbol;Acc:HGNC:11374] protein_coding
ENSG00000175793 2626.906816 1.043637 0.0767557 13.596863 0.0000000 0.0000000 ENSG00000175793.12 P31947 SFN SFN 2810 stratifin [Source:HGNC Symbol;Acc:HGNC:10773] protein_coding
ENSG00000059728 1098.802315 1.139353 0.0842708 13.520143 0.0000000 0.0000000 ENSG00000059728.11 Q05195 MXD1 MXD1 4084 MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761] protein_coding
ENSG00000091137 2888.864863 4.093254 0.3032182 13.499370 0.0000000 0.0000000 ENSG00000091137.14 O43511 SLC26A4 SLC26A4 5172 solute carrier family 26 member 4 [Source:HGNC Symbol;Acc:HGNC:8818] protein_coding
ENSG00000128039 1062.871624 1.052775 0.0784940 13.412181 0.0000000 0.0000000 ENSG00000128039.13 A0A7P0TBH6 SRD5A3 SRD5A3 79644 steroid 5 alpha-reductase 3 [Source:HGNC Symbol;Acc:HGNC:25812] protein_coding
ENSG00000181381 960.135442 1.059337 0.0790466 13.401428 0.0000000 0.0000000 ENSG00000181381.15 D6RBA2 DDX60L DDX60L 91351 DExD/H-box 60 like [Source:HGNC Symbol;Acc:HGNC:26429] protein_coding
ENSG00000041982 3444.001025 1.228951 0.0923387 13.309162 0.0000000 0.0000000 ENSG00000041982.17 A0A0U1RR80 TNC TNC 3371 tenascin C [Source:HGNC Symbol;Acc:HGNC:5318] protein_coding
ENSG00000104689 461.572386 1.255397 0.0947058 13.255758 0.0000000 0.0000000 ENSG00000104689.10 O00220 TNFRSF10A TNFRSF10A 8797 TNF receptor superfamily member 10a [Source:HGNC Symbol;Acc:HGNC:11904] protein_coding
ENSG00000100889 408.370440 1.746671 0.1317894 13.253507 0.0000000 0.0000000 ENSG00000100889.12 H0YNG4 PCK2 PCK2 5106 phosphoenolpyruvate carboxykinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:8725] protein_coding
ENSG00000163993 811.690361 1.457092 0.1100076 13.245376 0.0000000 0.0000000 ENSG00000163993.7 P25815 S100P S100P 6286 S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504] protein_coding
ENSG00000008517 258.222766 1.791775 0.1359182 13.182748 0.0000000 0.0000000 ENSG00000008517.19 F8W1V1 IL32 IL32 9235 interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830] protein_coding
ENSG00000176928 747.724626 1.135743 0.0861623 13.181435 0.0000000 0.0000000 ENSG00000176928.7 Q9P109 GCNT4 GCNT4 51301 glucosaminyl (N-acetyl) transferase 4 [Source:HGNC Symbol;Acc:HGNC:17973] protein_coding
ENSG00000137563 646.817608 1.411961 0.1072563 13.164361 0.0000000 0.0000000 ENSG00000137563.13 Q92820 GGH GGH 8836 gamma-glutamyl hydrolase [Source:HGNC Symbol;Acc:HGNC:4248] protein_coding
ENSG00000172432 667.145708 1.073114 0.0822093 13.053429 0.0000000 0.0000000 ENSG00000172432.19 H0YF05 GTPBP2 GTPBP2 54676 GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4670] protein_coding
ENSG00000175538 456.921044 1.363009 0.1045629 13.035311 0.0000000 0.0000000 ENSG00000175538.11 Q9Y6H6 KCNE3 KCNE3 10008 potassium voltage-gated channel subfamily E regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:6243] protein_coding
ENSG00000148339 310.448595 1.444291 0.1109160 13.021483 0.0000000 0.0000000 ENSG00000148339.13 Q6KCM7 SLC25A25 SLC25A25 114789 solute carrier family 25 member 25 [Source:HGNC Symbol;Acc:HGNC:20663] protein_coding
ENSG00000125089 170.593353 1.977599 0.1520245 13.008421 0.0000000 0.0000000 ENSG00000125089.18 A0A804HJH0 SH3TC1 SH3TC1 54436 SH3 domain and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:26009] protein_coding
ENSG00000090861 1675.440216 1.009235 0.0775901 13.007266 0.0000000 0.0000000 ENSG00000090861.17 A0A6Q8PHP7 AARS1 AARS1 16 alanyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:20] protein_coding
ENSG00000026508 9801.201960 1.702548 0.1314717 12.949920 0.0000000 0.0000000 ENSG00000026508.21 H0YCV9 CD44 CD44 960 CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] protein_coding
ENSG00000141524 700.894925 1.059446 0.0818104 12.950006 0.0000000 0.0000000 ENSG00000141524.19 Q7Z403 TMC6 TMC6 11322 transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021] protein_coding
ENSG00000142224 87.996501 5.509454 0.4254827 12.948714 0.0000000 0.0000000 ENSG00000142224.18 Q9UHD0 IL19 IL19 29949 interleukin 19 [Source:HGNC Symbol;Acc:HGNC:5990] protein_coding
ENSG00000117525 4025.999475 1.211564 0.0935818 12.946576 0.0000000 0.0000000 ENSG00000117525.14 P13726 F3 F3 2152 coagulation factor III, tissue factor [Source:HGNC Symbol;Acc:HGNC:3541] protein_coding
ENSG00000153822 420.909653 1.756084 0.1358746 12.924298 0.0000000 0.0000000 ENSG00000153822.15 Q9NPI9 KCNJ16 KCNJ16 3773 potassium inwardly rectifying channel subfamily J member 16 [Source:HGNC Symbol;Acc:HGNC:6262] protein_coding
ENSG00000172183 302.790277 1.578212 0.1222811 12.906423 0.0000000 0.0000000 ENSG00000172183.16 Q96AZ6 ISG20 ISG20 3669 interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130] protein_coding
ENSG00000227243 96.119598 4.347483 0.3376450 12.875901 0.0000000 0.0000000 ENSG00000227243.3 SLAMF6P1 NA SLAM family member 6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32012] unprocessed_pseudogene
ENSG00000114248 174.549137 6.824103 0.5309224 12.853295 0.0000000 0.0000000 ENSG00000114248.10 Q6UY01 LRRC31 LRRC31 79782 leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261] protein_coding
ENSG00000151651 248.395638 1.660904 0.1293318 12.842201 0.0000000 0.0000000 ENSG00000151651.16 H0YMT6 ADAM8 ADAM8 101 ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215] protein_coding
ENSG00000074590 418.827029 1.539205 0.1200721 12.819010 0.0000000 0.0000000 ENSG00000074590.14 O60285 NUAK1 NUAK1 9891 NUAK family kinase 1 [Source:HGNC Symbol;Acc:HGNC:14311] protein_coding
ENSG00000130513 888.772621 1.268669 0.0991819 12.791341 0.0000000 0.0000000 ENSG00000130513.7 Q99988 GDF15 GDF15 9518 growth differentiation factor 15 [Source:HGNC Symbol;Acc:HGNC:30142] protein_coding
ENSG00000188641 1464.970642 1.039916 0.0814273 12.771100 0.0000000 0.0000000 ENSG00000188641.14 Q12882 DPYD DPYD 1806 dihydropyrimidine dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3012] protein_coding
ENSG00000128165 129.316604 2.398849 0.1878640 12.769072 0.0000000 0.0000000 ENSG00000128165.9 Q7Z4H4 ADM2 ADM2 79924 adrenomedullin 2 [Source:HGNC Symbol;Acc:HGNC:28898] protein_coding
ENSG00000139304 492.376357 1.305020 0.1024431 12.738971 0.0000000 0.0000000 ENSG00000139304.16 A0A087WZU1 PTPRQ PTPRQ 374462 protein tyrosine phosphatase receptor type Q [Source:HGNC Symbol;Acc:HGNC:9679] protein_coding
ENSG00000268628 289.871111 1.943805 0.1538719 12.632620 0.0000000 0.0000000 ENSG00000268628.2 NA novel transcript lncRNA
ENSG00000134684 1183.527891 1.074048 0.0857141 12.530594 0.0000000 0.0000000 ENSG00000134684.13 A0A6Q8PFC1 YARS1 YARS1 8565 tyrosyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:12840] protein_coding
ENSG00000115267 773.156552 1.154767 0.0923659 12.502093 0.0000000 0.0000000 ENSG00000115267.10 A0A7P0Z4A9 IFIH1 IFIH1 64135 interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873] protein_coding
ENSG00000181649 441.077488 1.349525 0.1079626 12.499931 0.0000000 0.0000000 ENSG00000181649.8 Q53GA4 PHLDA2 PHLDA2 7262 pleckstrin homology like domain family A member 2 [Source:HGNC Symbol;Acc:HGNC:12385] protein_coding
ENSG00000139514 1609.932138 1.060904 0.0851326 12.461783 0.0000000 0.0000000 ENSG00000139514.13 Q5JR49 SLC7A1 SLC7A1 6541 solute carrier family 7 member 1 [Source:HGNC Symbol;Acc:HGNC:11057] protein_coding
ENSG00000162366 552.955602 1.831121 0.1471261 12.445933 0.0000000 0.0000000 ENSG00000162366.8 Q13113 PDZK1IP1 PDZK1IP1 10158 PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16887] protein_coding
ENSG00000174175 96.936094 3.494833 0.2810545 12.434715 0.0000000 0.0000000 ENSG00000174175.17 Q5R345 SELP SELP 6403 selectin P [Source:HGNC Symbol;Acc:HGNC:10721] protein_coding
ENSG00000101298 166.206429 2.717400 0.2198913 12.357920 0.0000000 0.0000000 ENSG00000101298.15 O15079 SNPH SNPH 9751 syntaphilin [Source:HGNC Symbol;Acc:HGNC:15931] protein_coding
ENSG00000164120 811.165728 1.009162 0.0816746 12.355883 0.0000000 0.0000000 ENSG00000164120.14 D6RA83 HPGD HPGD 3248 15-hydroxyprostaglandin dehydrogenase [Source:HGNC Symbol;Acc:HGNC:5154] protein_coding
ENSG00000145934 1727.042073 1.372552 0.1112151 12.341415 0.0000000 0.0000000 ENSG00000145934.17 F8VNQ3 TENM2 TENM2 57451 teneurin transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:29943] protein_coding
ENSG00000149809 734.887185 1.039690 0.0845148 12.301866 0.0000000 0.0000000 ENSG00000149809.17 A0A024R577 TM7SF2 TM7SF2 7108 transmembrane 7 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11863] protein_coding
ENSG00000111859 1076.610402 1.141829 0.0928283 12.300442 0.0000000 0.0000000 ENSG00000111859.17 D6RGD7 NEDD9 NEDD9 4739 neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733] protein_coding
ENSG00000147155 160.927658 2.321354 0.1889566 12.285116 0.0000000 0.0000000 ENSG00000147155.11 A0A024QYX0 EBP EBP 10682 EBP cholestenol delta-isomerase [Source:HGNC Symbol;Acc:HGNC:3133] protein_coding
ENSG00000168394 806.580207 1.085558 0.0884125 12.278340 0.0000000 0.0000000 ENSG00000168394.13 X5CKB3 TAP1 TAP1 6890 transporter 1, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:43] protein_coding
ENSG00000107960 615.197458 1.010319 0.0827565 12.208338 0.0000000 0.0000000 ENSG00000107960.12 A0A8V8TN12 STN1 STN1 79991 STN1 subunit of CST complex [Source:HGNC Symbol;Acc:HGNC:26200] protein_coding
ENSG00000140479 149.585352 2.150474 0.1762949 12.198166 0.0000000 0.0000000 ENSG00000140479.18 A0A7I2YQH5 PCSK6 PCSK6 5046 proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569] protein_coding
ENSG00000120756 6233.533474 1.029149 0.0844277 12.189709 0.0000000 0.0000000 ENSG00000120756.13 C9JYI1 PLS1 PLS1 5357 plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090] protein_coding
ENSG00000096433 2194.588233 1.001739 0.0830213 12.066053 0.0000000 0.0000000 ENSG00000096433.11 Q14573 ITPR3 ITPR3 3710 inositol 1,4,5-trisphosphate receptor type 3 [Source:HGNC Symbol;Acc:HGNC:6182] protein_coding
ENSG00000090512 204.676322 6.736381 0.5625706 11.974286 0.0000000 0.0000000 ENSG00000090512.12 Q9UGM5 FETUB FETUB 26998 fetuin B [Source:HGNC Symbol;Acc:HGNC:3658] protein_coding
ENSG00000188042 264.658159 1.524618 0.1276932 11.939695 0.0000000 0.0000000 ENSG00000188042.8 P56559 ARL4C ARL4C 10123 ADP ribosylation factor like GTPase 4C [Source:HGNC Symbol;Acc:HGNC:698] protein_coding
ENSG00000126549 87.571345 2.838303 0.2382016 11.915552 0.0000000 0.0000000 ENSG00000126549.11 P02808 STATH STATH 6779 statherin [Source:HGNC Symbol;Acc:HGNC:11369] protein_coding
ENSG00000169926 1074.553090 1.084699 0.0914061 11.866818 0.0000000 0.0000000 ENSG00000169926.11 Q9Y2Y9 KLF13 KLF13 51621 KLF transcription factor 13 [Source:HGNC Symbol;Acc:HGNC:13672] protein_coding
ENSG00000136802 2113.951654 1.081274 0.0911197 11.866527 0.0000000 0.0000000 ENSG00000136802.12 A0A024R892 LRRC8A LRRC8A 56262 leucine rich repeat containing 8 VRAC subunit A [Source:HGNC Symbol;Acc:HGNC:19027] protein_coding
ENSG00000113361 1812.776888 2.344303 0.1984636 11.812256 0.0000000 0.0000000 ENSG00000113361.13 P55285 CDH6 CDH6 1004 cadherin 6 [Source:HGNC Symbol;Acc:HGNC:1765] protein_coding
ENSG00000213214 186.216588 1.694308 0.1439211 11.772480 0.0000000 0.0000000 ENSG00000213214.6 A5YM69 ARHGEF35 ARHGEF35 445328 Rho guanine nucleotide exchange factor 35 [Source:HGNC Symbol;Acc:HGNC:33846] protein_coding
ENSG00000223784 70.968096 3.113568 0.2653082 11.735663 0.0000000 0.0000000 ENSG00000223784.2 LINP1 NA lncRNA in non-homologous end joining pathway 1 [Source:HGNC Symbol;Acc:HGNC:53170] lncRNA
ENSG00000147697 276.936595 1.436126 0.1224306 11.730120 0.0000000 0.0000000 ENSG00000147697.10 A0A2R8Y5J4 GSDMC GSDMC 56169 gasdermin C [Source:HGNC Symbol;Acc:HGNC:7151] protein_coding
ENSG00000108448 276.867865 1.354064 0.1158199 11.691120 0.0000000 0.0000000 ENSG00000108448.24 TRIM16L NA tripartite motif containing 16 like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:32670] transcribed_unprocessed_pseudogene
ENSG00000128283 902.742221 1.074974 0.0920169 11.682355 0.0000000 0.0000000 ENSG00000128283.7 Q00587 CDC42EP1 CDC42EP1 11135 CDC42 effector protein 1 [Source:HGNC Symbol;Acc:HGNC:17014] protein_coding
ENSG00000164379 618.921527 1.137735 0.0998066 11.399395 0.0000000 0.0000000 ENSG00000164379.7 Q9C009 FOXQ1 FOXQ1 94234 forkhead box Q1 [Source:HGNC Symbol;Acc:HGNC:20951] protein_coding
ENSG00000160326 143.089433 2.256283 0.1980953 11.389889 0.0000000 0.0000000 ENSG00000160326.14 Q9UGQ3 SLC2A6 SLC2A6 11182 solute carrier family 2 member 6 [Source:HGNC Symbol;Acc:HGNC:11011] protein_coding
ENSG00000221926 475.230173 1.211036 0.1065449 11.366438 0.0000000 0.0000000 ENSG00000221926.13 J3QKY5 TRIM16 TRIM16 10626 tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241] protein_coding
ENSG00000072042 745.522184 1.082020 0.0956644 11.310585 0.0000000 0.0000000 ENSG00000072042.13 G3V2G6 RDH11 RDH11 51109 retinol dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:17964] protein_coding
ENSG00000196639 237.070016 1.402274 0.1246230 11.252126 0.0000000 0.0000000 ENSG00000196639.7 P35367 HRH1 HRH1 3269 histamine receptor H1 [Source:HGNC Symbol;Acc:HGNC:5182] protein_coding
ENSG00000244694 376.354273 1.241330 0.1107704 11.206339 0.0000000 0.0000000 ENSG00000244694.8 A0A7P0TAD5 PTCHD4 PTCHD4 442213 patched domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21345] protein_coding
ENSG00000100344 89.280469 3.700652 0.3303129 11.203473 0.0000000 0.0000000 ENSG00000100344.11 F8W8E5 PNPLA3 PNPLA3 80339 patatin like phospholipase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18590] protein_coding
ENSG00000124813 281.548608 1.482284 0.1324890 11.187979 0.0000000 0.0000000 ENSG00000124813.23 Q13950 RUNX2 RUNX2 860 RUNX family transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10472] protein_coding
ENSG00000275395 2083.389464 1.691402 0.1524630 11.093852 0.0000000 0.0000000 ENSG00000275395.7 A0A087WXI2 FCGBP FCGBP 8857 Fc gamma binding protein [Source:HGNC Symbol;Acc:HGNC:13572] protein_coding
ENSG00000100078 80.716038 4.784838 0.4332008 11.045310 0.0000000 0.0000000 ENSG00000100078.4 Q9NZ20 PLA2G3 PLA2G3 50487 phospholipase A2 group III [Source:HGNC Symbol;Acc:HGNC:17934] protein_coding
ENSG00000176907 248.611930 2.026556 0.1838677 11.021816 0.0000000 0.0000000 ENSG00000176907.5 Q9NR00 TCIM TCIM 56892 transcriptional and immune response regulator [Source:HGNC Symbol;Acc:HGNC:1357] protein_coding
ENSG00000171992 1187.909073 1.002169 0.0912325 10.984775 0.0000000 0.0000000 ENSG00000171992.13 Q8N3V7 SYNPO SYNPO 11346 synaptopodin [Source:HGNC Symbol;Acc:HGNC:30672] protein_coding
ENSG00000132170 174.563752 1.629374 0.1490370 10.932680 0.0000000 0.0000000 ENSG00000132170.24 A0A3P3ZKM0 PPARG PPARG 5468 peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236] protein_coding
ENSG00000114738 388.796686 1.206801 0.1104471 10.926507 0.0000000 0.0000000 ENSG00000114738.11 A0A024R2W7 MAPKAPK3 MAPKAPK3 7867 MAPK activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6888] protein_coding
ENSG00000072858 483.430272 1.105452 0.1012310 10.920099 0.0000000 0.0000000 ENSG00000072858.11 Q9NXL6 SIDT1 SIDT1 54847 SID1 transmembrane family member 1 [Source:HGNC Symbol;Acc:HGNC:25967] protein_coding
ENSG00000169439 163.599715 2.034320 0.1867154 10.895301 0.0000000 0.0000000 ENSG00000169439.12 E9PBI9 SDC2 SDC2 6383 syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] protein_coding
ENSG00000119121 65.230056 3.645485 0.3358235 10.855360 0.0000000 0.0000000 ENSG00000119121.22 Q9BX84 TRPM6 TRPM6 140803 transient receptor potential cation channel subfamily M member 6 [Source:HGNC Symbol;Acc:HGNC:17995] protein_coding
ENSG00000171124 407.115746 1.131068 0.1042122 10.853508 0.0000000 0.0000000 ENSG00000171124.14 P21217 FUT3 FUT3 2525 fucosyltransferase 3 (Lewis blood group) [Source:HGNC Symbol;Acc:HGNC:4014] protein_coding
ENSG00000114378 77.818016 2.797521 0.2578627 10.848875 0.0000000 0.0000000 ENSG00000114378.17 C9JRK1 HYAL1 HYAL1 3373 hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:5320] protein_coding
ENSG00000066230 70.197131 3.279570 0.3028992 10.827265 0.0000000 0.0000000 ENSG00000066230.12 P48764 SLC9A3 SLC9A3 6550 solute carrier family 9 member A3 [Source:HGNC Symbol;Acc:HGNC:11073] protein_coding
ENSG00000135114 325.049251 1.544988 0.1430775 10.798258 0.0000000 0.0000000 ENSG00000135114.14 A0A7P0T9H8 OASL OASL 8638 2’-5’-oligoadenylate synthetase like [Source:HGNC Symbol;Acc:HGNC:8090] protein_coding
ENSG00000168679 439.632518 1.233076 0.1141942 10.798064 0.0000000 0.0000000 ENSG00000168679.18 E9PKZ1 SLC16A4 SLC16A4 9122 solute carrier family 16 member 4 [Source:HGNC Symbol;Acc:HGNC:10925] protein_coding
ENSG00000138135 244.719427 1.759686 0.1634969 10.762807 0.0000000 0.0000000 ENSG00000138135.7 O95992 CH25H CH25H 9023 cholesterol 25-hydroxylase [Source:HGNC Symbol;Acc:HGNC:1907] protein_coding
ENSG00000082497 749.124502 1.027621 0.0954827 10.762373 0.0000000 0.0000000 ENSG00000082497.12 Q9NUC0 SERTAD4 SERTAD4 56256 SERTA domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25236] protein_coding
ENSG00000151617 70.897733 3.271047 0.3045135 10.741877 0.0000000 0.0000000 ENSG00000151617.17 P25101 EDNRA EDNRA 1909 endothelin receptor type A [Source:HGNC Symbol;Acc:HGNC:3179] protein_coding
ENSG00000130766 433.262229 1.109499 0.1040311 10.665062 0.0000000 0.0000000 ENSG00000130766.5 P58004 SESN2 SESN2 83667 sestrin 2 [Source:HGNC Symbol;Acc:HGNC:20746] protein_coding
ENSG00000185507 379.091279 1.071018 0.1005293 10.653795 0.0000000 0.0000000 ENSG00000185507.21 M9RSF4 IRF7 IRF7 3665 interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122] protein_coding
ENSG00000073008 315.591508 1.368448 0.1285306 10.646864 0.0000000 0.0000000 ENSG00000073008.16 A0A0A0MSA9 PVR PVR 5817 PVR cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:9705] protein_coding
ENSG00000006327 554.727132 1.003163 0.0945882 10.605583 0.0000000 0.0000000 ENSG00000006327.14 I3L1J9 TNFRSF12A TNFRSF12A 51330 TNF receptor superfamily member 12A [Source:HGNC Symbol;Acc:HGNC:18152] protein_coding
ENSG00000130487 536.345822 1.164728 0.1100282 10.585727 0.0000000 0.0000000 ENSG00000130487.9 Q96G42 KLHDC7B KLHDC7B 113730 kelch domain containing 7B [Source:HGNC Symbol;Acc:HGNC:25145] protein_coding
ENSG00000204267 321.622936 1.323208 0.1254098 10.551069 0.0000000 0.0000000 ENSG00000204267.19 A0A8V8TNJ0 TAP2 TAP2 6891 transporter 2, ATP binding cassette subfamily B member [Source:HGNC Symbol;Acc:HGNC:44] protein_coding
ENSG00000169035 108.709781 1.987591 0.1884378 10.547729 0.0000000 0.0000000 ENSG00000169035.12 P49862 KLK7 KLK7 5650 kallikrein related peptidase 7 [Source:HGNC Symbol;Acc:HGNC:6368] protein_coding
ENSG00000115008 463.408510 1.153585 0.1099018 10.496515 0.0000000 0.0000000 ENSG00000115008.6 P01583 IL1A IL1A 3552 interleukin 1 alpha [Source:HGNC Symbol;Acc:HGNC:5991] protein_coding
ENSG00000103257 1147.144119 1.083551 0.1038643 10.432369 0.0000000 0.0000000 ENSG00000103257.9 Q01650 SLC7A5 SLC7A5 8140 solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063] protein_coding
ENSG00000121552 1558.370175 1.163393 0.1116067 10.424037 0.0000000 0.0000000 ENSG00000121552.4 P01040 CSTA CSTA 1475 cystatin A [Source:HGNC Symbol;Acc:HGNC:2481] protein_coding
ENSG00000198488 100.618529 2.529394 0.2427835 10.418314 0.0000000 0.0000000 ENSG00000198488.10 Q6ZMB0 B3GNT6 B3GNT6 192134 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:24141] protein_coding
ENSG00000177494 136.585006 1.733522 0.1664391 10.415353 0.0000000 0.0000000 ENSG00000177494.6 Q9BTP6 ZBED2 ZBED2 79413 zinc finger BED-type containing 2 [Source:HGNC Symbol;Acc:HGNC:20710] protein_coding
ENSG00000188910 456.330744 1.052786 0.1011844 10.404623 0.0000000 0.0000000 ENSG00000188910.8 O75712 GJB3 GJB3 2707 gap junction protein beta 3 [Source:HGNC Symbol;Acc:HGNC:4285] protein_coding
ENSG00000165125 47.264062 4.215032 0.4051330 10.404071 0.0000000 0.0000000 ENSG00000165125.22 C9J9W0 TRPV6 TRPV6 55503 transient receptor potential cation channel subfamily V member 6 [Source:HGNC Symbol;Acc:HGNC:14006] protein_coding
ENSG00000131746 1524.222745 1.154875 0.1110599 10.398662 0.0000000 0.0000000 ENSG00000131746.13 Q8IZW8 TNS4 TNS4 84951 tensin 4 [Source:HGNC Symbol;Acc:HGNC:24352] protein_coding
ENSG00000141682 897.014308 1.021430 0.0982472 10.396532 0.0000000 0.0000000 ENSG00000141682.12 Q13794 PMAIP1 PMAIP1 5366 phorbol-12-myristate-13-acetate-induced protein 1 [Source:HGNC Symbol;Acc:HGNC:9108] protein_coding
ENSG00000141574 390.914929 1.055315 0.1015574 10.391313 0.0000000 0.0000000 ENSG00000141574.8 J3QR99 SECTM1 SECTM1 6398 secreted and transmembrane 1 [Source:HGNC Symbol;Acc:HGNC:10707] protein_coding
ENSG00000186854 97.560545 2.512783 0.2427478 10.351415 0.0000000 0.0000000 ENSG00000186854.11 Q86V40 TRABD2A TRABD2A 105374836 TraB domain containing 2A [Source:HGNC Symbol;Acc:HGNC:27013] protein_coding
ENSG00000140279 1733.105258 1.567071 0.1515652 10.339256 0.0000000 0.0000000 ENSG00000140279.13 Q9NRD8 DUOX2 DUOX2 50506 dual oxidase 2 [Source:HGNC Symbol;Acc:HGNC:13273] protein_coding
ENSG00000170345 310.867128 1.215761 0.1182040 10.285276 0.0000000 0.0000000 ENSG00000170345.10 G3V5N9 FOS FOS 2353 Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796] protein_coding
ENSG00000120738 880.976693 1.099846 0.1072038 10.259387 0.0000000 0.0000000 ENSG00000120738.8 P18146 EGR1 EGR1 1958 early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238] protein_coding
ENSG00000169116 1987.614556 1.135062 0.1110926 10.217256 0.0000000 0.0000000 ENSG00000169116.11 D6RBB6 PARM1 PARM1 25849 prostate androgen-regulated mucin-like protein 1 [Source:HGNC Symbol;Acc:HGNC:24536] protein_coding
ENSG00000185022 345.493630 1.184036 0.1166546 10.149930 0.0000000 0.0000000 ENSG00000185022.12 Q9ULX9 MAFF MAFF 23764 MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780] protein_coding
ENSG00000169474 145.726750 2.064719 0.2037174 10.135213 0.0000000 0.0000000 ENSG00000169474.5 P35321 SPRR1A SPRR1A 6698 small proline rich protein 1A [Source:HGNC Symbol;Acc:HGNC:11259] protein_coding
ENSG00000122861 1597.066605 1.148333 0.1134177 10.124814 0.0000000 0.0000000 ENSG00000122861.16 P00749 PLAU PLAU 5328 plasminogen activator, urokinase [Source:HGNC Symbol;Acc:HGNC:9052] protein_coding
ENSG00000112715 609.780400 1.182288 0.1168814 10.115276 0.0000000 0.0000000 ENSG00000112715.26 A0A024RD33 VEGF VEGFA 7422 vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] protein_coding
ENSG00000012171 124.554623 1.843364 0.1825090 10.100129 0.0000000 0.0000000 ENSG00000012171.20 B4DEK9 SEMA3B SEMA3B 7869 semaphorin 3B [Source:HGNC Symbol;Acc:HGNC:10724] protein_coding
ENSG00000256870 167.124294 2.166095 0.2160628 10.025302 0.0000000 0.0000000 ENSG00000256870.3 Q8N695 SLC5A8 SLC5A8 160728 solute carrier family 5 member 8 [Source:HGNC Symbol;Acc:HGNC:19119] protein_coding
ENSG00000131203 816.376563 1.208833 0.1221129 9.899307 0.0000000 0.0000000 ENSG00000131203.13 A0A140T9Z2 IDO1 IDO1 3620 indoleamine 2,3-dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:6059] protein_coding
ENSG00000163251 385.429003 1.142738 0.1158096 9.867381 0.0000000 0.0000000 ENSG00000163251.4 Q13467 FZD5 FZD5 7855 frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043] protein_coding
ENSG00000060982 178.733490 1.353674 0.1376261 9.835887 0.0000000 0.0000000 ENSG00000060982.15 P54687 BCAT1 BCAT1 586 branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976] protein_coding
ENSG00000127666 334.019550 1.038916 0.1064936 9.755672 0.0000000 0.0000000 ENSG00000127666.11 Q8IUC6 TICAM1 TICAM1 148022 TIR domain containing adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:18348] protein_coding
ENSG00000203722 218.489428 1.330362 0.1363868 9.754330 0.0000000 0.0000000 ENSG00000203722.8 Q6H3X3 RAET1G RAET1G 353091 retinoic acid early transcript 1G [Source:HGNC Symbol;Acc:HGNC:16795] protein_coding
ENSG00000162512 385.143858 1.112460 0.1145744 9.709498 0.0000000 0.0000000 ENSG00000162512.16 O75056 SDC3 SDC3 9672 syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660] protein_coding
ENSG00000092621 306.647644 1.213353 0.1252328 9.688784 0.0000000 0.0000000 ENSG00000092621.13 A0A2C9F2M7 PHGDH PHGDH 26227 phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923] protein_coding
ENSG00000197646 70.465740 2.438143 0.2520429 9.673521 0.0000000 0.0000000 ENSG00000197646.8 Q9BQ51 PDCD1LG2 PDCD1LG2 80380 programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] protein_coding
ENSG00000258689 86.610058 1.965474 0.2048156 9.596312 0.0000000 0.0000000 ENSG00000258689.2 LINC01269 103695436 long intergenic non-protein coding RNA 1269 [Source:HGNC Symbol;Acc:HGNC:50325] lncRNA
ENSG00000121281 248.941858 1.136373 0.1189838 9.550655 0.0000000 0.0000000 ENSG00000121281.13 H3BQ93 ADCY7 ADCY7 113 adenylate cyclase 7 [Source:HGNC Symbol;Acc:HGNC:238] protein_coding
ENSG00000128383 78.832706 2.932012 0.3074709 9.535902 0.0000000 0.0000000 ENSG00000128383.14 P31941 APOBEC3A APOBEC3A 100913187 apolipoprotein B mRNA editing enzyme catalytic subunit 3A [Source:HGNC Symbol;Acc:HGNC:17343] protein_coding
ENSG00000134262 190.332759 1.373774 0.1446959 9.494214 0.0000000 0.0000000 ENSG00000134262.14 Q9Y6B7 AP4B1 AP4B1 10717 adaptor related protein complex 4 subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:572] protein_coding
ENSG00000167617 135.393864 1.675185 0.1771385 9.456925 0.0000000 0.0000000 ENSG00000167617.3 Q6NZY7 CDC42EP5 CDC42EP5 148170 CDC42 effector protein 5 [Source:HGNC Symbol;Acc:HGNC:17408] protein_coding
ENSG00000068971 223.111442 1.182828 0.1251890 9.448340 0.0000000 0.0000000 ENSG00000068971.14 Q15173 PPP2R5B PPP2R5B 5526 protein phosphatase 2 regulatory subunit B’beta [Source:HGNC Symbol;Acc:HGNC:9310] protein_coding
ENSG00000166123 323.537003 1.190681 0.1264369 9.417192 0.0000000 0.0000000 ENSG00000166123.14 Q8TD30 GPT2 GPT2 84706 glutamic–pyruvic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:18062] protein_coding
ENSG00000154310 267.831668 1.160976 0.1233497 9.412069 0.0000000 0.0000000 ENSG00000154310.17 Q9UKE5 TNIK TNIK 23043 TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:HGNC:30765] protein_coding
ENSG00000182389 92.234641 2.121373 0.2258802 9.391585 0.0000000 0.0000000 ENSG00000182389.20 H0Y476 CACNB4 CACNB4 785 calcium voltage-gated channel auxiliary subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:1404] protein_coding
ENSG00000124882 196.608661 1.295628 0.1385665 9.350219 0.0000000 0.0000000 ENSG00000124882.4 O14944 EREG EREG 2069 epiregulin [Source:HGNC Symbol;Acc:HGNC:3443] protein_coding
ENSG00000155966 87.289878 1.981088 0.2132185 9.291351 0.0000000 0.0000000 ENSG00000155966.14 P51816 AFF2 AFF2 2334 ALF transcription elongation factor 2 [Source:HGNC Symbol;Acc:HGNC:3776] protein_coding
ENSG00000001630 68.042902 2.667544 0.2880047 9.262156 0.0000000 0.0000000 ENSG00000001630.18 Q16850 CYP51A1 CYP51A1 1595 cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649] protein_coding
ENSG00000164574 440.681900 1.055954 0.1143522 9.234226 0.0000000 0.0000000 ENSG00000164574.16 F2Z2M7 GALNT10 GALNT10 55568 polypeptide N-acetylgalactosaminyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19873] protein_coding
ENSG00000141480 294.259336 1.048512 0.1136474 9.226015 0.0000000 0.0000000 ENSG00000141480.18 P32121 ARRB2 ARRB2 409 arrestin beta 2 [Source:HGNC Symbol;Acc:HGNC:712] protein_coding
ENSG00000103089 226.833282 1.269462 0.1379136 9.204759 0.0000000 0.0000000 ENSG00000103089.9 H3BP32 FA2H FA2H 79152 fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197] protein_coding
ENSG00000204959 149.979785 1.474466 0.1603034 9.197973 0.0000000 0.0000000 ENSG00000204959.4 ARHGEF34P NA Rho guanine nucleotide exchange factor 34, pseudogene [Source:HGNC Symbol;Acc:HGNC:38086] unprocessed_pseudogene
ENSG00000242265 333.737479 1.494181 0.1626475 9.186618 0.0000000 0.0000000 ENSG00000242265.6 A0A087WX23 PEG10 PEG10 23089 paternally expressed 10 [Source:HGNC Symbol;Acc:HGNC:14005] protein_coding
ENSG00000172059 219.345711 1.215353 0.1323034 9.186109 0.0000000 0.0000000 ENSG00000172059.11 B5MCC4 KLF11 KLF11 8462 KLF transcription factor 11 [Source:HGNC Symbol;Acc:HGNC:11811] protein_coding
ENSG00000126709 571.992656 1.101548 0.1206487 9.130210 0.0000000 0.0000000 ENSG00000126709.16 P09912 IFI6 IFI6 2537 interferon alpha inducible protein 6 [Source:HGNC Symbol;Acc:HGNC:4054] protein_coding
ENSG00000078018 369.864288 1.187095 0.1300470 9.128196 0.0000000 0.0000000 ENSG00000078018.22 A0A669KB77 MAP2 MAP2 4133 microtubule associated protein 2 [Source:HGNC Symbol;Acc:HGNC:6839] protein_coding
ENSG00000215424 87.277528 1.961213 0.2173979 9.021308 0.0000000 0.0000000 ENSG00000215424.10 MCM3AP-AS1 114044 MCM3AP antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:16417] lncRNA
ENSG00000068079 206.479124 1.224148 0.1362408 8.985178 0.0000000 0.0000000 ENSG00000068079.8 P80217 IFI35 IFI35 3430 interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399] protein_coding
ENSG00000140853 150.424271 1.415348 0.1580875 8.952939 0.0000000 0.0000000 ENSG00000140853.17 H0YFT1 NLRC5 NLRC5 84166 NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933] protein_coding
ENSG00000157193 271.732315 1.090741 0.1219577 8.943606 0.0000000 0.0000000 ENSG00000157193.18 A0A590UK45 LRP8 LRP8 7804 LDL receptor related protein 8 [Source:HGNC Symbol;Acc:HGNC:6700] protein_coding
ENSG00000114993 300.049168 1.073270 0.1203901 8.914937 0.0000000 0.0000000 ENSG00000114993.17 Q9BST9 RTKN RTKN 6242 rhotekin [Source:HGNC Symbol;Acc:HGNC:10466] protein_coding
ENSG00000133106 339.843685 1.007145 0.1133819 8.882772 0.0000000 0.0000000 ENSG00000133106.15 F5H799 EPSTI1 EPSTI1 94240 epithelial stromal interaction 1 [Source:HGNC Symbol;Acc:HGNC:16465] protein_coding
ENSG00000182010 241.689488 1.123438 0.1269230 8.851331 0.0000000 0.0000000 ENSG00000182010.11 Q8IZC4 RTKN2 RTKN2 219790 rhotekin 2 [Source:HGNC Symbol;Acc:HGNC:19364] protein_coding
ENSG00000105388 4110.302352 1.198411 0.1362089 8.798331 0.0000000 0.0000000 ENSG00000105388.17 P06731 CEACAM5 CEACAM5 1048 CEA cell adhesion molecule 5 [Source:HGNC Symbol;Acc:HGNC:1817] protein_coding
ENSG00000276045 255.242807 1.060131 0.1218263 8.701984 0.0000000 0.0000000 ENSG00000276045.4 Q96D31 ORAI1 ORAI1 84876 ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896] protein_coding
ENSG00000167207 99.237812 1.590090 0.1833500 8.672430 0.0000000 0.0000000 ENSG00000167207.15 Q9HC29 NOD2 NOD2 64127 nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331] protein_coding
ENSG00000251152 310.855164 1.050494 0.1214835 8.647218 0.0000000 0.0000000 ENSG00000251152.1 NA novel transcript lncRNA
ENSG00000165233 188.493506 1.204787 0.1394796 8.637732 0.0000000 0.0000000 ENSG00000165233.18 Q96LW7 CARD19 CARD19 84270 caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] protein_coding
ENSG00000152137 256.485771 1.089431 0.1262143 8.631595 0.0000000 0.0000000 ENSG00000152137.8 A0A6Q8PGM6 HSPB8 HSPB8 26353 heat shock protein family B (small) member 8 [Source:HGNC Symbol;Acc:HGNC:30171] protein_coding
ENSG00000077150 422.546740 1.002875 0.1164954 8.608708 0.0000000 0.0000000 ENSG00000077150.21 Q00653 NFKB2 NFKB2 4791 nuclear factor kappa B subunit 2 [Source:HGNC Symbol;Acc:HGNC:7795] protein_coding
ENSG00000184160 32.783144 4.660709 0.5415096 8.606882 0.0000000 0.0000000 ENSG00000184160.8 P18825 ADRA2C ADRA2C 152 adrenoceptor alpha 2C [Source:HGNC Symbol;Acc:HGNC:283] protein_coding
ENSG00000136010 71.223480 2.026100 0.2362201 8.577170 0.0000000 0.0000000 ENSG00000136010.14 Q3SY69 ALDH1L2 ALDH1L2 160428 aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777] protein_coding
ENSG00000101000 51.141016 2.531979 0.2960176 8.553473 0.0000000 0.0000000 ENSG00000101000.6 A0A0U1RRC4 PROCR PROCR 10544 protein C receptor [Source:HGNC Symbol;Acc:HGNC:9452] protein_coding
ENSG00000179914 79.467140 2.251978 0.2655722 8.479719 0.0000000 0.0000000 ENSG00000179914.5 Q8WWA0 ITLN1 ITLN1 55600 intelectin 1 [Source:HGNC Symbol;Acc:HGNC:18259] protein_coding
ENSG00000105641 36.224941 4.186479 0.4940372 8.474017 0.0000000 0.0000000 ENSG00000105641.4 Q92911 SLC5A5 SLC5A5 6528 solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] protein_coding
ENSG00000165899 46.180373 4.811224 0.5677903 8.473592 0.0000000 0.0000000 ENSG00000165899.12 H0YIL4 OTOGL OTOGL 283310 otogelin like [Source:HGNC Symbol;Acc:HGNC:26901] protein_coding
ENSG00000142273 199.416947 1.128123 0.1333416 8.460398 0.0000000 0.0000000 ENSG00000142273.13 Q9ULV8 CBLC CBLC 23624 Cbl proto-oncogene C [Source:HGNC Symbol;Acc:HGNC:15961] protein_coding
ENSG00000130303 291.983426 1.067193 0.1262589 8.452423 0.0000000 0.0000000 ENSG00000130303.14 Q10589 BST2 BST2 684 bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119] protein_coding
ENSG00000169429 6723.677238 1.379253 0.1632411 8.449181 0.0000000 0.0000000 ENSG00000169429.12 C9J4T6 CXCL8 CXCL8 3576 C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] protein_coding
ENSG00000159763 155.715189 1.221644 0.1449788 8.426364 0.0000000 0.0000000 ENSG00000159763.4 P12273 PIP PIP 5304 prolactin induced protein [Source:HGNC Symbol;Acc:HGNC:8993] protein_coding
ENSG00000127152 168.800722 1.466250 0.1741332 8.420277 0.0000000 0.0000000 ENSG00000127152.18 D3YTK1 BCL11B BCL11B 64919 BCL11 transcription factor B [Source:HGNC Symbol;Acc:HGNC:13222] protein_coding
ENSG00000173846 226.784344 1.172086 0.1405782 8.337605 0.0000000 0.0000000 ENSG00000173846.13 Q9H4B4 PLK3 PLK3 1263 polo like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2154] protein_coding
ENSG00000184545 152.527574 1.233803 0.1485382 8.306299 0.0000000 0.0000000 ENSG00000184545.11 Q13202 DUSP8 DUSP8 1850 dual specificity phosphatase 8 [Source:HGNC Symbol;Acc:HGNC:3074] protein_coding
ENSG00000182580 245.396789 1.100734 0.1328963 8.282654 0.0000000 0.0000000 ENSG00000182580.3 P54753 EPHB3 EPHB3 2049 EPH receptor B3 [Source:HGNC Symbol;Acc:HGNC:3394] protein_coding
ENSG00000166510 170.629769 1.234164 0.1490253 8.281572 0.0000000 0.0000000 ENSG00000166510.14 A0A024R2B9 CCDC68 CCDC68 80323 coiled-coil domain containing 68 [Source:HGNC Symbol;Acc:HGNC:24350] protein_coding
ENSG00000114771 79.230086 2.699403 0.3264198 8.269728 0.0000000 0.0000000 ENSG00000114771.14 P22760 AADAC AADAC 13 arylacetamide deacetylase [Source:HGNC Symbol;Acc:HGNC:17] protein_coding
ENSG00000133110 73.579917 2.371925 0.2874408 8.251873 0.0000000 0.0000000 ENSG00000133110.15 A0A024RDS2 POSTN POSTN 10631 periostin [Source:HGNC Symbol;Acc:HGNC:16953] protein_coding
ENSG00000006062 146.203986 1.328317 0.1625757 8.170453 0.0000000 0.0000000 ENSG00000006062.18 Q99558 MAP3K14 MAP3K14 9020 mitogen-activated protein kinase kinase kinase 14 [Source:HGNC Symbol;Acc:HGNC:6853] protein_coding
ENSG00000168899 62.688166 2.090603 0.2565167 8.149969 0.0000000 0.0000000 ENSG00000168899.5 O95183 VAMP5 VAMP5 10791 vesicle associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:12646] protein_coding
ENSG00000153391 258.709166 1.026930 0.1268029 8.098634 0.0000000 0.0000000 ENSG00000153391.16 K7EKI6 INO80C INO80C 125476 INO80 complex subunit C [Source:HGNC Symbol;Acc:HGNC:26994] protein_coding
ENSG00000120254 223.923676 1.062437 0.1329174 7.993215 0.0000000 0.0000000 ENSG00000120254.16 Q4VXM1 MTHFD1L MTHFD1L 25902 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like [Source:HGNC Symbol;Acc:HGNC:21055] protein_coding
ENSG00000103888 455.011361 1.789463 0.2245166 7.970294 0.0000000 0.0000000 ENSG00000103888.17 Q8WUJ3 CEMIP CEMIP 57214 cell migration inducing hyaluronidase 1 [Source:HGNC Symbol;Acc:HGNC:29213] protein_coding
ENSG00000163209 253.161053 2.691776 0.3377415 7.969928 0.0000000 0.0000000 ENSG00000163209.15 Q9UBC9 SPRR3 SPRR3 6707 small proline rich protein 3 [Source:HGNC Symbol;Acc:HGNC:11268] protein_coding
ENSG00000040608 61.052075 2.166853 0.2725480 7.950355 0.0000000 0.0000000 ENSG00000040608.14 Q9BZR6 RTN4R RTN4R 65078 reticulon 4 receptor [Source:HGNC Symbol;Acc:HGNC:18601] protein_coding
ENSG00000184304 57.517257 2.210268 0.2803315 7.884480 0.0000000 0.0000000 ENSG00000184304.17 H0YHS9 PRKD1 PRKD1 5587 protein kinase D1 [Source:HGNC Symbol;Acc:HGNC:9407] protein_coding
ENSG00000198873 50.846771 2.474524 0.3141910 7.875858 0.0000000 0.0000000 ENSG00000198873.12 P34947 GRK5 GRK5 2869 G protein-coupled receptor kinase 5 [Source:HGNC Symbol;Acc:HGNC:4544] protein_coding
ENSG00000184113 42.504105 5.927328 0.7547854 7.852998 0.0000000 0.0000000 ENSG00000184113.10 O00501 CLDN5 CLDN5 7122 claudin 5 [Source:HGNC Symbol;Acc:HGNC:2047] protein_coding
ENSG00000174502 44.345742 2.752209 0.3512726 7.834966 0.0000000 0.0000000 ENSG00000174502.19 Q7LBE3 SLC26A9 SLC26A9 115019 solute carrier family 26 member 9 [Source:HGNC Symbol;Acc:HGNC:14469] protein_coding
ENSG00000161955 249.811216 1.040270 0.1328393 7.831047 0.0000000 0.0000000 ENSG00000161955.17 Q2QBA2 TNFSF13 TNFSF13 8741 TNF superfamily member 13 [Source:HGNC Symbol;Acc:HGNC:11928] protein_coding
ENSG00000279806 141.901807 1.320848 0.1689652 7.817275 0.0000000 0.0000000 ENSG00000279806.1 NA TEC TEC
ENSG00000135218 232.060484 1.327949 0.1698870 7.816661 0.0000000 0.0000000 ENSG00000135218.19 E7EU05 CD36 CD36 948 CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663] protein_coding
ENSG00000168621 38.310366 4.055340 0.5190630 7.812809 0.0000000 0.0000000 ENSG00000168621.15 A0A0C4DGC2 GDNF GDNF 2668 glial cell derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:4232] protein_coding
ENSG00000198400 54.359739 9.293399 1.1953328 7.774738 0.0000000 0.0000000 ENSG00000198400.14 A0A6Q8PF65 NTRK1 NTRK1 4914 neurotrophic receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:8031] protein_coding
ENSG00000165507 179.917699 1.144921 0.1481096 7.730226 0.0000000 0.0000000 ENSG00000165507.9 Q9NTK1 DEPP1 DEPP1 11067 DEPP autophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:23355] protein_coding
ENSG00000137267 103.087389 1.437090 0.1869974 7.685080 0.0000000 0.0000000 ENSG00000137267.7 Q13885 TUBB2A TUBB2A 7280 tubulin beta 2A class IIa [Source:HGNC Symbol;Acc:HGNC:12412] protein_coding
ENSG00000138685 217.835597 1.101718 0.1434378 7.680808 0.0000000 0.0000000 ENSG00000138685.18 P09038 FGF2 FGF2 2247 fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] protein_coding
ENSG00000170955 197.729396 1.004061 0.1319985 7.606614 0.0000000 0.0000000 ENSG00000170955.10 Q969G5 CAVIN3 CAVIN3 112464 caveolae associated protein 3 [Source:HGNC Symbol;Acc:HGNC:9400] protein_coding
ENSG00000184979 152.158847 1.110343 0.1463589 7.586437 0.0000000 0.0000000 ENSG00000184979.11 A0A8V8TMN0 USP18 USP18 11274 ubiquitin specific peptidase 18 [Source:HGNC Symbol;Acc:HGNC:12616] protein_coding
ENSG00000160191 124.648614 1.444680 0.1906424 7.577957 0.0000000 0.0000000 ENSG00000160191.18 O76083 PDE9A PDE9A 5152 phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795] protein_coding
ENSG00000179241 206.360125 1.027861 0.1367609 7.515755 0.0000000 0.0000000 ENSG00000179241.13 Q86YD5 LDLRAD3 LDLRAD3 143458 low density lipoprotein receptor class A domain containing 3 [Source:HGNC Symbol;Acc:HGNC:27046] protein_coding
ENSG00000224420 31.116397 4.263456 0.5677580 7.509284 0.0000000 0.0000000 ENSG00000224420.4 C9JUS6 ADM5 ADM5 199800 adrenomedullin 5 (putative) [Source:HGNC Symbol;Acc:HGNC:27293] protein_coding
ENSG00000105327 154.606108 1.135926 0.1515377 7.495999 0.0000000 0.0000000 ENSG00000105327.18 Q96PG8 BBC3 BBC3 27113 BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868] protein_coding
ENSG00000176092 162.972256 1.163555 0.1561936 7.449437 0.0000000 0.0000000 ENSG00000176092.17 Q8N1P7 CRYBG2 CRYBG2 55057 crystallin beta-gamma domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17295] protein_coding
ENSG00000031081 82.888053 1.541385 0.2081799 7.404101 0.0000000 0.0000000 ENSG00000031081.11 C9J652 ARHGAP31 ARHGAP31 57514 Rho GTPase activating protein 31 [Source:HGNC Symbol;Acc:HGNC:29216] protein_coding
ENSG00000143882 76.268382 1.630577 0.2204924 7.395163 0.0000000 0.0000000 ENSG00000143882.12 Q8NEY4 ATP6V1C2 ATP6V1C2 245973 ATPase H+ transporting V1 subunit C2 [Source:HGNC Symbol;Acc:HGNC:18264] protein_coding
ENSG00000162551 148.270545 1.271473 0.1720262 7.391159 0.0000000 0.0000000 ENSG00000162551.14 A0A024RAB4 ALPL ALPL 249 alkaline phosphatase, biomineralization associated [Source:HGNC Symbol;Acc:HGNC:438] protein_coding
ENSG00000172345 144.924450 1.101944 0.1492137 7.385006 0.0000000 0.0000000 ENSG00000172345.14 Q9NSY2 STARD5 STARD5 80765 StAR related lipid transfer domain containing 5 [Source:HGNC Symbol;Acc:HGNC:18065] protein_coding
ENSG00000169894 79.112638 1.623441 0.2206393 7.357897 0.0000000 0.0000000 ENSG00000169894.18 Q02505 MUC3A MUC3A 4584 mucin 3A, cell surface associated [Source:HGNC Symbol;Acc:HGNC:7513] protein_coding
ENSG00000050730 142.937001 1.583465 0.2156850 7.341565 0.0000000 0.0000000 ENSG00000050730.16 Q96KP6 TNIP3 TNIP3 79931 TNFAIP3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:19315] protein_coding
ENSG00000215853 26.845844 3.470809 0.4747642 7.310596 0.0000000 0.0000000 ENSG00000215853.3 Q6XPR3 RPTN RPTN 126638 repetin [Source:HGNC Symbol;Acc:HGNC:26809] protein_coding
ENSG00000136688 112.484666 1.592508 0.2180548 7.303250 0.0000000 0.0000000 ENSG00000136688.11 C9J681 IL36G IL36G 56300 interleukin 36 gamma [Source:HGNC Symbol;Acc:HGNC:15741] protein_coding
ENSG00000171711 82.018488 2.267726 0.3137840 7.227030 0.0000000 0.0000000 ENSG00000171711.3 O15263 DEFB4A DEFB4A 124906748 defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767] protein_coding
ENSG00000118729 43.852720 2.916055 0.4049996 7.200143 0.0000000 0.0000000 ENSG00000118729.13 O14958 CASQ2 CASQ2 845 calsequestrin 2 [Source:HGNC Symbol;Acc:HGNC:1513] protein_coding
ENSG00000237975 102.916591 1.419949 0.1975907 7.186319 0.0000000 0.0000000 ENSG00000237975.7 FLG-AS1 339400 FLG antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27913] lncRNA
ENSG00000225434 169.113504 1.048758 0.1464251 7.162419 0.0000000 0.0000000 ENSG00000225434.5 LINC01504 100507540 long intergenic non-protein coding RNA 1504 [Source:HGNC Symbol;Acc:HGNC:51185] lncRNA
ENSG00000183098 89.469355 1.451230 0.2028956 7.152594 0.0000000 0.0000000 ENSG00000183098.12 Q9Y625 GPC6 GPC6 10082 glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454] protein_coding
ENSG00000187678 70.116881 1.619917 0.2264907 7.152244 0.0000000 0.0000000 ENSG00000187678.10 Q9C004 SPRY4 SPRY4 81848 sprouty RTK signaling antagonist 4 [Source:HGNC Symbol;Acc:HGNC:15533] protein_coding
ENSG00000169583 161.382184 1.209206 0.1694421 7.136394 0.0000000 0.0000000 ENSG00000169583.13 O95833 CLIC3 CLIC3 9022 chloride intracellular channel 3 [Source:HGNC Symbol;Acc:HGNC:2064] protein_coding
ENSG00000072832 75.162747 1.636650 0.2302266 7.108865 0.0000000 0.0000000 ENSG00000072832.15 Q14194 CRMP1 CRMP1 1400 collapsin response mediator protein 1 [Source:HGNC Symbol;Acc:HGNC:2365] protein_coding
ENSG00000112182 112.849949 1.298217 0.1827208 7.104920 0.0000000 0.0000000 ENSG00000112182.16 Q9BYV9 BACH2 BACH2 60468 BTB domain and CNC homolog 2 [Source:HGNC Symbol;Acc:HGNC:14078] protein_coding
ENSG00000104856 254.284739 1.003801 0.1413776 7.100143 0.0000000 0.0000000 ENSG00000104856.15 Q01201 RELB RELB 5971 RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956] protein_coding
ENSG00000164509 123.933087 1.288547 0.1819258 7.082815 0.0000000 0.0000000 ENSG00000164509.16 A0A494C190 IL31RA IL31RA 133396 interleukin 31 receptor A [Source:HGNC Symbol;Acc:HGNC:18969] protein_coding
ENSG00000204520 170.001114 1.016690 0.1440784 7.056507 0.0000000 0.0000000 ENSG00000204520.14 A0A1W2PRA6 MICA MICA 100507436 MHC class I polypeptide-related sequence A [Source:HGNC Symbol;Acc:HGNC:7090] protein_coding
ENSG00000146859 122.745563 1.150471 0.1635120 7.036003 0.0000000 0.0000000 ENSG00000146859.6 Q9NV12 TMEM140 TMEM140 55281 transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870] protein_coding
ENSG00000168062 82.105884 1.543760 0.2203921 7.004610 0.0000000 0.0000000 ENSG00000168062.10 Q8N1L9 BATF2 BATF2 116071 basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163] protein_coding
ENSG00000006652 145.153391 1.091784 0.1568041 6.962724 0.0000000 0.0000000 ENSG00000006652.15 C9J7U6 IFRD1 IFRD1 3475 interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456] protein_coding
ENSG00000111432 36.484598 2.982545 0.4290670 6.951235 0.0000000 0.0000000 ENSG00000111432.5 Q9ULW2 FZD10 FZD10 11211 frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039] protein_coding
ENSG00000035664 137.723862 1.095683 0.1577042 6.947708 0.0000000 0.0000000 ENSG00000035664.11 H0YLP5 DAPK2 DAPK2 23604 death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675] protein_coding
ENSG00000178826 66.688322 1.540460 0.2221090 6.935602 0.0000000 0.0000000 ENSG00000178826.11 Q8IV31 TMEM139 TMEM139 135932 transmembrane protein 139 [Source:HGNC Symbol;Acc:HGNC:22058] protein_coding
ENSG00000115602 33.881709 2.284116 0.3301925 6.917529 0.0000000 0.0000000 ENSG00000115602.17 C9JSY6 IL1RL1 IL1RL1 9173 interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] protein_coding
ENSG00000164236 68.788940 1.637747 0.2369508 6.911757 0.0000000 0.0000000 ENSG00000164236.12 A6NCL7 ANKRD33B ANKRD33B 651746 ankyrin repeat domain 33B [Source:HGNC Symbol;Acc:HGNC:35240] protein_coding
ENSG00000144655 171.586043 1.037724 0.1511132 6.867194 0.0000000 0.0000000 ENSG00000144655.15 Q96S65 CSRNP1 CSRNP1 64651 cysteine and serine rich nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:14300] protein_coding
ENSG00000203706 91.657722 1.456190 0.2123483 6.857552 0.0000000 0.0000000 ENSG00000203706.9 SERTAD4-AS1 NA SERTAD4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:32019] lncRNA
ENSG00000080031 114.740928 1.231140 0.1804357 6.823152 0.0000000 0.0000000 ENSG00000080031.10 Q9HD43 PTPRH PTPRH 5794 protein tyrosine phosphatase receptor type H [Source:HGNC Symbol;Acc:HGNC:9672] protein_coding
ENSG00000078098 92.197264 1.615831 0.2371192 6.814427 0.0000000 0.0000000 ENSG00000078098.15 Q12884 FAP FAP 2191 fibroblast activation protein alpha [Source:HGNC Symbol;Acc:HGNC:3590] protein_coding
ENSG00000059377 38.886152 2.296673 0.3399476 6.755961 0.0000000 0.0000000 ENSG00000059377.19 C9JS68 TBXAS1 TBXAS1 6916 thromboxane A synthase 1 [Source:HGNC Symbol;Acc:HGNC:11609] protein_coding
ENSG00000146858 142.066540 1.053062 0.1566691 6.721570 0.0000000 0.0000000 ENSG00000146858.8 Q96H79 ZC3HAV1L ZC3HAV1L 92092 zinc finger CCCH-type containing, antiviral 1 like [Source:HGNC Symbol;Acc:HGNC:22423] protein_coding
ENSG00000121742 55.356677 1.699842 0.2535208 6.704940 0.0000000 0.0000000 ENSG00000121742.19 O95452 GJB6 GJB6 10804 gap junction protein beta 6 [Source:HGNC Symbol;Acc:HGNC:4288] protein_coding
ENSG00000112195 50.789635 7.979448 1.1939621 6.683167 0.0000000 0.0000000 ENSG00000112195.9 Q5T2D2 TREML2 TREML2 79865 triggering receptor expressed on myeloid cells like 2 [Source:HGNC Symbol;Acc:HGNC:21092] protein_coding
ENSG00000174669 126.412944 1.166057 0.1747815 6.671514 0.0000000 0.0000000 ENSG00000174669.12 Q14542 SLC29A2 SLC29A2 3177 solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004] protein_coding
ENSG00000249631 235.424586 1.037659 0.1564522 6.632436 0.0000000 0.0000000 ENSG00000249631.7 107986178 novel transcript lncRNA
ENSG00000185885 137.969198 1.176840 0.1782354 6.602728 0.0000000 0.0000000 ENSG00000185885.17 A0A7P0TB03 IFITM1 IFITM1 8519 interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412] protein_coding
ENSG00000013016 119.910597 1.279455 0.1947469 6.569836 0.0000000 0.0000000 ENSG00000013016.16 Q9NZN3 EHD3 EHD3 30845 EH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:3244] protein_coding
ENSG00000285820 73.079411 1.456346 0.2224251 6.547580 0.0000000 0.0000000 ENSG00000285820.1 NA Novel transcript, antisense to ASTN2 lncRNA
ENSG00000158055 126.428801 1.095323 0.1675737 6.536367 0.0000000 0.0000000 ENSG00000158055.17 A0A8I5KUQ1 GRHL3 GRHL3 57822 grainyhead like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:25839] protein_coding
ENSG00000260630 119.701953 1.191318 0.1826688 6.521740 0.0000000 0.0000000 ENSG00000260630.9 SNAI3-AS1 197187 SNAI3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:28327] lncRNA
ENSG00000196684 135.413236 1.044074 0.1606969 6.497166 0.0000000 0.0000000 ENSG00000196684.12 A0A087X0V9 HSH2D HSH2D 84941 hematopoietic SH2 domain containing [Source:HGNC Symbol;Acc:HGNC:24920] protein_coding
ENSG00000184574 115.500546 1.113153 0.1714406 6.492933 0.0000000 0.0000000 ENSG00000184574.10 Q9H1C0 LPAR5 LPAR5 57121 lysophosphatidic acid receptor 5 [Source:HGNC Symbol;Acc:HGNC:13307] protein_coding
ENSG00000241322 144.829886 1.328121 0.2045750 6.492100 0.0000000 0.0000000 ENSG00000241322.11 A0A087WSX6 FBXW10B FBXW10B 374286 F-box and WD repeat domain containing 10B [Source:HGNC Symbol;Acc:HGNC:14379] protein_coding
ENSG00000123405 27.154316 3.025751 0.4695597 6.443804 0.0000000 0.0000000 ENSG00000123405.14 A8K3E0 NFE2 NFE2 4778 nuclear factor, erythroid 2 [Source:HGNC Symbol;Acc:HGNC:7780] protein_coding
ENSG00000142227 114.748738 1.152158 0.1797241 6.410703 0.0000000 0.0000000 ENSG00000142227.11 M0QZ66 EMP3 EMP3 2014 epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335] protein_coding
ENSG00000257242 44.934216 1.855583 0.2913017 6.369970 0.0000000 0.0000000 ENSG00000257242.9 LINC01619 256021 long intergenic non-protein coding RNA 1619 [Source:HGNC Symbol;Acc:HGNC:27409] lncRNA
ENSG00000251493 77.322154 1.423510 0.2240843 6.352563 0.0000000 0.0000000 ENSG00000251493.5 Q16676 FOXD1 FOXD1 2297 forkhead box D1 [Source:HGNC Symbol;Acc:HGNC:3802] protein_coding
ENSG00000133067 29.084190 3.376890 0.5331210 6.334190 0.0000000 0.0000000 ENSG00000133067.18 Q9HBX8 LGR6 LGR6 59352 leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719] protein_coding
ENSG00000283160 92.905981 1.213453 0.1918849 6.323861 0.0000000 0.0000000 ENSG00000283160.1 MIR4521 100616406 microRNA 4521 [Source:HGNC Symbol;Acc:HGNC:41813] miRNA
ENSG00000115756 127.023078 1.094941 0.1734888 6.311308 0.0000000 0.0000000 ENSG00000115756.13 Q6FGY1 HPCAL1 HPCAL1 3241 hippocalcin like 1 [Source:HGNC Symbol;Acc:HGNC:5145] protein_coding
ENSG00000260196 45.951970 1.824762 0.2911286 6.267890 0.0000000 0.0000000 ENSG00000260196.1 NA antisense to KCNJ11 and overlapping to a novel gene lncRNA
ENSG00000267107 52.508308 1.848316 0.2954528 6.255875 0.0000000 0.0000000 ENSG00000267107.9 PCAT19 100505495 prostate cancer associated transcript 19 [Source:HGNC Symbol;Acc:HGNC:49593] lncRNA
ENSG00000183010 80.391674 1.274503 0.2042156 6.240970 0.0000000 0.0000000 ENSG00000183010.17 J3QKT4 PYCR1 PYCR1 5831 pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:HGNC:9721] protein_coding
ENSG00000244198 43.728091 2.086121 0.3348133 6.230700 0.0000000 0.0000000 ENSG00000244198.7 ARHGEF35-AS1 NA ARHGEF35 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41292] lncRNA
ENSG00000101187 66.077110 1.560354 0.2510958 6.214177 0.0000000 0.0000000 ENSG00000101187.16 Q96BD0 SLCO4A1 SLCO4A1 28231 solute carrier organic anion transporter family member 4A1 [Source:HGNC Symbol;Acc:HGNC:10953] protein_coding
ENSG00000140379 71.226561 1.437712 0.2313648 6.214049 0.0000000 0.0000000 ENSG00000140379.9 Q16548 BCL2A1 BCL2A1 597 BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] protein_coding
ENSG00000184227 99.076063 1.206762 0.1955041 6.172568 0.0000000 0.0000000 ENSG00000184227.8 Q86TX2 ACOT1 ACOT1 641371 acyl-CoA thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:33128] protein_coding
ENSG00000170373 19.656429 7.516938 1.2241186 6.140694 0.0000000 0.0000000 ENSG00000170373.9 P01037 CST1 CST1 1469 cystatin SN [Source:HGNC Symbol;Acc:HGNC:2473] protein_coding
ENSG00000196549 51.017189 1.918729 0.3131107 6.127957 0.0000000 0.0000000 ENSG00000196549.13 P08473 MME MME 4311 membrane metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:7154] protein_coding
ENSG00000213886 88.568486 1.249759 0.2045250 6.110542 0.0000000 0.0000000 ENSG00000213886.4 A0A1U9X8S6 FAT10 UBD 10537 ubiquitin D [Source:HGNC Symbol;Acc:HGNC:18795] protein_coding
ENSG00000171476 45.407356 2.213434 0.3624760 6.106428 0.0000000 0.0000000 ENSG00000171476.23 Q9BPY8 HOPX HOPX 84525 HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961] protein_coding
ENSG00000188404 34.418413 2.430335 0.3980283 6.105935 0.0000000 0.0000000 ENSG00000188404.10 P14151 SELL SELL 6402 selectin L [Source:HGNC Symbol;Acc:HGNC:10720] protein_coding
ENSG00000157833 38.459159 2.243553 0.3683514 6.090797 0.0000000 0.0000000 ENSG00000157833.13 Q75VX8 GAREM2 GAREM2 150946 GRB2 associated regulator of MAPK1 subtype 2 [Source:HGNC Symbol;Acc:HGNC:27172] protein_coding
ENSG00000171791 85.954412 1.183715 0.1946393 6.081580 0.0000000 0.0000000 ENSG00000171791.14 A0A7I2V5Q7 BCL2 BCL2 596 BCL2 apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:990] protein_coding
ENSG00000280219 21.709831 2.597128 0.4277728 6.071279 0.0000000 0.0000000 ENSG00000280219.1 NA TEC TEC
ENSG00000230438 86.256866 1.221251 0.2013492 6.065336 0.0000000 0.0000000 ENSG00000230438.9 SERPINB9P1 NA serpin family B member 9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:28590] lncRNA
ENSG00000138311 102.856794 1.090734 0.1802943 6.049745 0.0000000 0.0000000 ENSG00000138311.18 Q70YC5 ZNF365 ZNF365 22891 zinc finger protein 365 [Source:HGNC Symbol;Acc:HGNC:18194] protein_coding
ENSG00000146054 123.634679 1.133654 0.1882837 6.020990 0.0000000 0.0000000 ENSG00000146054.18 Q9C029 TRIM7 TRIM7 81786 tripartite motif containing 7 [Source:HGNC Symbol;Acc:HGNC:16278] protein_coding
ENSG00000238837 119.046269 1.114909 0.1854506 6.011892 0.0000000 0.0000000 ENSG00000238837.3 LINC02031 NA long intergenic non-protein coding RNA 2031 [Source:HGNC Symbol;Acc:HGNC:52865] lncRNA
ENSG00000169248 76.225151 1.710791 0.2848149 6.006677 0.0000000 0.0000000 ENSG00000169248.13 O14625 CXCL11 CXCL11 6373 C-X-C motif chemokine ligand 11 [Source:HGNC Symbol;Acc:HGNC:10638] protein_coding
ENSG00000140931 109.017702 1.129621 0.1881619 6.003450 0.0000000 0.0000000 ENSG00000140931.20 I3L3C2 CMTM3 CMTM3 123920 CKLF like MARVEL transmembrane domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19174] protein_coding
ENSG00000104415 18.820219 4.694996 0.7969304 5.891351 0.0000000 0.0000000 ENSG00000104415.14 E5RG88 CCN4 CCN4 8840 cellular communication network factor 4 [Source:HGNC Symbol;Acc:HGNC:12769] protein_coding
ENSG00000163053 141.448750 1.008285 0.1713125 5.885645 0.0000000 0.0000000 ENSG00000163053.11 Q7RTX9 SLC16A14 SLC16A14 151473 solute carrier family 16 member 14 [Source:HGNC Symbol;Acc:HGNC:26417] protein_coding
ENSG00000187583 85.494552 1.096670 0.1874128 5.851628 0.0000000 0.0000001 ENSG00000187583.11 J3KSM5 PLEKHN1 PLEKHN1 84069 pleckstrin homology domain containing N1 [Source:HGNC Symbol;Acc:HGNC:25284] protein_coding
ENSG00000120833 88.352178 1.168478 0.2005015 5.827777 0.0000000 0.0000001 ENSG00000120833.14 O14508 SOCS2 SOCS2 8835 suppressor of cytokine signaling 2 [Source:HGNC Symbol;Acc:HGNC:19382] protein_coding
ENSG00000175197 99.616077 1.148172 0.1981523 5.794391 0.0000000 0.0000001 ENSG00000175197.13 P35638 DDIT3 DDIT3 1649 DNA damage inducible transcript 3 [Source:HGNC Symbol;Acc:HGNC:2726] protein_coding
ENSG00000241794 149.938713 2.486031 0.4311828 5.765610 0.0000000 0.0000001 ENSG00000241794.2 P35326 SPRR2A SPRR2A 6700 small proline rich protein 2A [Source:HGNC Symbol;Acc:HGNC:11261] protein_coding
ENSG00000182472 75.057789 1.274863 0.2211873 5.763726 0.0000000 0.0000001 ENSG00000182472.9 M0QZT6 CAPN12 CAPN12 147968 calpain 12 [Source:HGNC Symbol;Acc:HGNC:13249] protein_coding
ENSG00000138166 530.496274 1.447451 0.2512025 5.762089 0.0000000 0.0000001 ENSG00000138166.6 Q16690 DUSP5 DUSP5 1847 dual specificity phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:3071] protein_coding
ENSG00000247596 112.113947 1.008521 0.1751593 5.757735 0.0000000 0.0000001 ENSG00000247596.10 A0A7I2V5B1 TWF2 TWF2 11344 twinfilin actin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9621] protein_coding
ENSG00000142156 30.443561 2.119801 0.3692288 5.741159 0.0000000 0.0000001 ENSG00000142156.16 P12109 COL6A1 COL6A1 1291 collagen type VI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2211] protein_coding
ENSG00000278910 13.907980 7.042900 1.2365290 5.695701 0.0000000 0.0000001 ENSG00000278910.5 BANCR NA BRAF-activated non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:43877] lncRNA
ENSG00000285427 35.841489 2.106526 0.3713360 5.672830 0.0000000 0.0000001 ENSG00000285427.1 SOD2-OT1 100129518 SOD2 overlapping transcript 1 [Source:HGNC Symbol;Acc:HGNC:53445] lncRNA
ENSG00000127528 141.467140 1.166517 0.2067948 5.640943 0.0000000 0.0000002 ENSG00000127528.6 Q9Y5W3 KLF2 KLF2 10365 KLF transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:6347] protein_coding
ENSG00000160471 82.592058 1.171615 0.2078130 5.637833 0.0000000 0.0000002 ENSG00000160471.13 Q6YFQ2 COX6B2 COX6B2 125965 cytochrome c oxidase subunit 6B2 [Source:HGNC Symbol;Acc:HGNC:24380] protein_coding
ENSG00000164088 61.619806 1.401833 0.2497651 5.612608 0.0000000 0.0000002 ENSG00000164088.18 Q96MI6 PPM1M PPM1M 132160 protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506] protein_coding
ENSG00000107485 96.572207 1.067527 0.1906465 5.599508 0.0000000 0.0000002 ENSG00000107485.18 A0A2R8Y2A9 GATA3 GATA3 2625 GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172] protein_coding
ENSG00000148600 81.951719 1.397936 0.2501343 5.588740 0.0000000 0.0000002 ENSG00000148600.15 Q96JP9 CDHR1 CDHR1 92211 cadherin related family member 1 [Source:HGNC Symbol;Acc:HGNC:14550] protein_coding
ENSG00000049249 24.422051 2.407113 0.4318415 5.574066 0.0000000 0.0000002 ENSG00000049249.10 Q07011 TNFRSF9 TNFRSF9 3604 TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] protein_coding
ENSG00000176697 35.459100 1.884994 0.3384349 5.569737 0.0000000 0.0000002 ENSG00000176697.20 P23560 BDNF BDNF 627 brain derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:1033] protein_coding
ENSG00000130775 41.092606 1.653240 0.2983535 5.541213 0.0000000 0.0000003 ENSG00000130775.16 X6RK39 THEMIS2 THEMIS2 9473 thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839] protein_coding
ENSG00000179593 557.921180 1.172549 0.2126411 5.514215 0.0000000 0.0000003 ENSG00000179593.16 O15296 ALOX15B ALOX15B 247 arachidonate 15-lipoxygenase type B [Source:HGNC Symbol;Acc:HGNC:434] protein_coding
ENSG00000234147 17.899432 4.385637 0.7984142 5.492935 0.0000000 0.0000004 ENSG00000234147.4 NA novel transcript lncRNA
ENSG00000159231 71.742967 1.311031 0.2398530 5.465977 0.0000000 0.0000004 ENSG00000159231.6 O75828 CBR3 CBR3 874 carbonyl reductase 3 [Source:HGNC Symbol;Acc:HGNC:1549] protein_coding
ENSG00000127951 20.513199 6.540114 1.2171360 5.373364 0.0000001 0.0000007 ENSG00000127951.8 A4D1B8 FGL2 FGL2 10875 fibrinogen like 2 [Source:HGNC Symbol;Acc:HGNC:3696] protein_coding
ENSG00000167419 22.701385 2.524812 0.4730291 5.337542 0.0000001 0.0000009 ENSG00000167419.11 F5H386 LPO LPO 4025 lactoperoxidase [Source:HGNC Symbol;Acc:HGNC:6678] protein_coding
ENSG00000285108 50.408409 1.844019 0.3462719 5.325350 0.0000001 0.0000009 ENSG00000285108.1 NA novel transcript lncRNA
ENSG00000107201 94.900245 1.171942 0.2211150 5.300147 0.0000001 0.0000010 ENSG00000107201.11 A0A7P0Z425 RIGI RIGI 23586 RNA sensor RIG-I [Source:HGNC Symbol;Acc:HGNC:19102] protein_coding
ENSG00000185052 28.437320 2.203944 0.4162581 5.294658 0.0000001 0.0000011 ENSG00000185052.13 Q9HC58 SLC24A3 SLC24A3 57419 solute carrier family 24 member 3 [Source:HGNC Symbol;Acc:HGNC:10977] protein_coding
ENSG00000170542 88.260917 1.143746 0.2172213 5.265351 0.0000001 0.0000012 ENSG00000170542.6 P50453 SERPINB9 SERPINB9 5272 serpin family B member 9 [Source:HGNC Symbol;Acc:HGNC:8955] protein_coding
ENSG00000141497 49.679971 1.347439 0.2559237 5.265002 0.0000001 0.0000012 ENSG00000141497.14 Q9H091 ZMYND15 ZMYND15 84225 zinc finger MYND-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20997] protein_coding
ENSG00000167105 45.068217 1.517551 0.2885276 5.259639 0.0000001 0.0000013 ENSG00000167105.8 Q6UXU6 TMEM92 TMEM92 162461 transmembrane protein 92 [Source:HGNC Symbol;Acc:HGNC:26579] protein_coding
ENSG00000142619 27.201255 2.521810 0.4812127 5.240531 0.0000002 0.0000014 ENSG00000142619.4 Q9ULW8 PADI3 PADI3 51702 peptidyl arginine deiminase 3 [Source:HGNC Symbol;Acc:HGNC:18337] protein_coding
ENSG00000104332 35.460564 1.785845 0.3425978 5.212658 0.0000002 0.0000016 ENSG00000104332.12 Q8N474 SFRP1 SFRP1 6422 secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] protein_coding
ENSG00000007129 10.458824 6.546833 1.2610987 5.191373 0.0000002 0.0000018 ENSG00000007129.18 Q3KPI0 CEACAM21 CEACAM21 90273 CEA cell adhesion molecule 21 [Source:HGNC Symbol;Acc:HGNC:28834] protein_coding
ENSG00000141540 31.790091 1.826516 0.3523307 5.184095 0.0000002 0.0000019 ENSG00000141540.11 B4DKD1 TTYH2 TTYH2 94015 tweety family member 2 [Source:HGNC Symbol;Acc:HGNC:13877] protein_coding
ENSG00000197506 80.006448 1.018827 0.1972262 5.165777 0.0000002 0.0000021 ENSG00000197506.8 Q9HAS3 SLC28A3 SLC28A3 64078 solute carrier family 28 member 3 [Source:HGNC Symbol;Acc:HGNC:16484] protein_coding
ENSG00000088826 62.322965 1.241492 0.2405201 5.161696 0.0000002 0.0000021 ENSG00000088826.18 Q9NWM0 SMOX SMOX 54498 spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862] protein_coding
ENSG00000147119 88.076999 1.002493 0.1960817 5.112631 0.0000003 0.0000027 ENSG00000147119.4 Q9NS84 CHST7 CHST7 56548 carbohydrate sulfotransferase 7 [Source:HGNC Symbol;Acc:HGNC:13817] protein_coding
ENSG00000288018 29.042260 1.875403 0.3681622 5.093959 0.0000004 0.0000030 ENSG00000288018.3 101929174 novel transcript lncRNA
ENSG00000167123 89.748562 1.281478 0.2520179 5.084871 0.0000004 0.0000031 ENSG00000167123.20 X6RL83 CERCAM CERCAM 51148 cerebral endothelial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:23723] protein_coding
ENSG00000188001 59.385533 1.214176 0.2404606 5.049376 0.0000004 0.0000037 ENSG00000188001.10 C9JDW1 TPRG1 TPRG1 285386 tumor protein p63 regulated 1 [Source:HGNC Symbol;Acc:HGNC:24759] protein_coding
ENSG00000169245 285.008493 2.215773 0.4393542 5.043251 0.0000005 0.0000038 ENSG00000169245.6 P02778 CXCL10 CXCL10 3627 C-X-C motif chemokine ligand 10 [Source:HGNC Symbol;Acc:HGNC:10637] protein_coding
ENSG00000232977 15.526673 3.135671 0.6219925 5.041332 0.0000005 0.0000038 ENSG00000232977.7 LINC00327 100506697 long intergenic non-protein coding RNA 327 [Source:HGNC Symbol;Acc:HGNC:42009] lncRNA
ENSG00000134242 17.855203 2.473847 0.5006501 4.941270 0.0000008 0.0000062 ENSG00000134242.16 E9PMK2 PTPN22 PTPN22 26191 protein tyrosine phosphatase non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652] protein_coding
ENSG00000166546 18.174592 2.109392 0.4309242 4.895042 0.0000010 0.0000077 ENSG00000166546.15 Q3B7T3 BEAN1 BEAN1 146227 brain expressed associated with NEDD4 1 [Source:HGNC Symbol;Acc:HGNC:24160] protein_coding
ENSG00000042832 41.970780 1.345242 0.2749098 4.893395 0.0000010 0.0000078 ENSG00000042832.12 E5RG33 TG TG 7038 thyroglobulin [Source:HGNC Symbol;Acc:HGNC:11764] protein_coding
ENSG00000164181 85.976763 1.002914 0.2069269 4.846708 0.0000013 0.0000097 ENSG00000164181.14 D6RBM2 ELOVL7 ELOVL7 79993 ELOVL fatty acid elongase 7 [Source:HGNC Symbol;Acc:HGNC:26292] protein_coding
ENSG00000289268 53.918169 1.353504 0.2804269 4.826583 0.0000014 0.0000107 ENSG00000289268.1 NA novel transcript lncRNA
ENSG00000231106 37.426227 1.630669 0.3404412 4.789868 0.0000017 0.0000127 ENSG00000231106.3 LINC01436 NA long intergenic non-protein coding RNA 1436 [Source:HGNC Symbol;Acc:HGNC:50754] lncRNA
ENSG00000204544 24.486149 2.007453 0.4220904 4.755978 0.0000020 0.0000149 ENSG00000204544.5 Q5SSG8 MUC21 MUC21 394263 mucin 21, cell surface associated [Source:HGNC Symbol;Acc:HGNC:21661] protein_coding
ENSG00000182601 22.167484 2.311483 0.4887835 4.729052 0.0000023 0.0000168 ENSG00000182601.7 Q9Y661 HS3ST4 HS3ST4 9951 heparan sulfate-glucosamine 3-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:5200] protein_coding
ENSG00000105499 44.225486 1.297742 0.2745264 4.727204 0.0000023 0.0000170 ENSG00000105499.14 M0R1B4 PLA2G4C PLA2G4C 8605 phospholipase A2 group IVC [Source:HGNC Symbol;Acc:HGNC:9037] protein_coding
ENSG00000109099 9.779680 3.262655 0.6914314 4.718698 0.0000024 0.0000177 ENSG00000109099.16 J3KT36 PMP22 PMP22 5376 peripheral myelin protein 22 [Source:HGNC Symbol;Acc:HGNC:9118] protein_coding
ENSG00000204839 44.410817 1.303974 0.2786901 4.678940 0.0000029 0.0000212 ENSG00000204839.9 A6NGR9 MROH6 MROH6 642475 maestro heat like repeat family member 6 [Source:HGNC Symbol;Acc:HGNC:27814] protein_coding
ENSG00000173868 11.217035 5.873177 1.2691704 4.627572 0.0000037 0.0000267 ENSG00000173868.12 D6RIT6 PHOSPHO1 PHOSPHO1 162466 phosphoethanolamine/phosphocholine phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:16815] protein_coding
ENSG00000255521 12.389747 3.267098 0.7078479 4.615537 0.0000039 0.0000282 ENSG00000255521.3 CD44-DT 100507144 CD44 divergent transcript [Source:HGNC Symbol;Acc:HGNC:56175] lncRNA
ENSG00000225177 47.516704 1.293697 0.2803972 4.613800 0.0000040 0.0000284 ENSG00000225177.6 NHSL1-AS1 124900217 NHSL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40947] lncRNA
ENSG00000165140 65.311354 1.007641 0.2189109 4.602973 0.0000042 0.0000298 ENSG00000165140.12 P09467 FBP1 FBP1 2203 fructose-bisphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3606] protein_coding
ENSG00000130208 13.334621 3.226620 0.7013055 4.600877 0.0000042 0.0000301 ENSG00000130208.10 P02654 APOC1 APOC1 341 apolipoprotein C1 [Source:HGNC Symbol;Acc:HGNC:607] protein_coding
ENSG00000233292 26.622607 1.742118 0.3828759 4.550085 0.0000054 0.0000376 ENSG00000233292.1 NA novel zinc finger pseudogene processed_pseudogene
ENSG00000233930 71.300957 1.075243 0.2382617 4.512863 0.0000064 0.0000442 ENSG00000233930.4 KRTAP5-AS1 338651 KRTAP5-1/KRTAP5-2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27877] lncRNA
ENSG00000162873 34.522303 1.369641 0.3061970 4.473070 0.0000077 0.0000527 ENSG00000162873.15 U3KPX9 KLHDC8A KLHDC8A 55220 kelch domain containing 8A [Source:HGNC Symbol;Acc:HGNC:25573] protein_coding
ENSG00000164451 15.160270 5.540633 1.2393336 4.470655 0.0000078 0.0000532 ENSG00000164451.14 Q5JW98 CALHM4 CALHM4 221301 calcium homeostasis modulator family member 4 [Source:HGNC Symbol;Acc:HGNC:21094] protein_coding
ENSG00000219891 26.308695 1.547061 0.3483283 4.441387 0.0000089 0.0000604 ENSG00000219891.4 ZSCAN12P1 NA zinc finger and SCAN domain containing 12 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13850] transcribed_unprocessed_pseudogene
ENSG00000266729 12.124074 2.986537 0.6729184 4.438186 0.0000091 0.0000612 ENSG00000266729.5 DSG1-AS1 101927718 DSG1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51115] lncRNA
ENSG00000114279 63.583000 1.066109 0.2408288 4.426833 0.0000096 0.0000643 ENSG00000114279.15 C9JIN3 FGF12 FGF12 2257 fibroblast growth factor 12 [Source:HGNC Symbol;Acc:HGNC:3668] protein_coding
ENSG00000078401 84.428258 1.017126 0.2300410 4.421498 0.0000098 0.0000658 ENSG00000078401.7 P05305 EDN1 EDN1 1906 endothelin 1 [Source:HGNC Symbol;Acc:HGNC:3176] protein_coding
ENSG00000126545 12.294394 4.842536 1.1007991 4.399110 0.0000109 0.0000723 ENSG00000126545.14 P47710 CSN1S1 CSN1S1 1446 casein alpha s1 [Source:HGNC Symbol;Acc:HGNC:2445] protein_coding
ENSG00000140274 95.200443 1.113295 0.2534965 4.391756 0.0000112 0.0000747 ENSG00000140274.14 Q1HG44 DUOXA2 DUOXA2 405753 dual oxidase maturation factor 2 [Source:HGNC Symbol;Acc:HGNC:32698] protein_coding
ENSG00000279277 47.263676 1.275550 0.2906062 4.389274 0.0000114 0.0000754 ENSG00000279277.2 NA novel transcript lncRNA
ENSG00000148488 70.263346 1.017309 0.2329039 4.367933 0.0000125 0.0000827 ENSG00000148488.17 P61647 ST8SIA6 ST8SIA6 338596 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:23317] protein_coding
ENSG00000144681 25.720244 1.555740 0.3570941 4.356667 0.0000132 0.0000865 ENSG00000144681.11 Q99469 STAC STAC 6769 SH3 and cysteine rich domain [Source:HGNC Symbol;Acc:HGNC:11353] protein_coding
ENSG00000114013 52.827218 1.031675 0.2387132 4.321818 0.0000155 0.0001002 ENSG00000114013.16 P42081 CD86 CD86 942 CD86 molecule [Source:HGNC Symbol;Acc:HGNC:1705] protein_coding
ENSG00000130222 33.701335 1.427786 0.3316798 4.304711 0.0000167 0.0001077 ENSG00000130222.11 Q5VZ88 GADD45G GADD45G 10912 growth arrest and DNA damage inducible gamma [Source:HGNC Symbol;Acc:HGNC:4097] protein_coding
ENSG00000123358 31.191040 1.402027 0.3276427 4.279132 0.0000188 0.0001197 ENSG00000123358.20 H3BSM8 NR4A1 NR4A1 3164 nuclear receptor subfamily 4 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7980] protein_coding
ENSG00000123685 17.467316 1.958902 0.4586413 4.271097 0.0000195 0.0001235 ENSG00000123685.9 Q9NR55 BATF3 BATF3 55509 basic leucine zipper ATF-like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:28915] protein_coding
ENSG00000259924 15.945556 2.245724 0.5276957 4.255718 0.0000208 0.0001320 ENSG00000259924.1 NA DnaJ (Hsp40) homolog, subfamily B, member 14 pseudogene processed_pseudogene
ENSG00000222182 19.288060 2.122420 0.4994982 4.249104 0.0000215 0.0001355 ENSG00000222182.1 RNA5SP156 NA RNA, 5S ribosomal pseudogene 156 [Source:HGNC Symbol;Acc:HGNC:43056] rRNA_pseudogene
ENSG00000067191 54.231281 1.077103 0.2542546 4.236315 0.0000227 0.0001429 ENSG00000067191.17 Q02641 CACNB1 CACNB1 782 calcium voltage-gated channel auxiliary subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:1401] protein_coding
ENSG00000204869 11.075262 3.172841 0.7502479 4.229057 0.0000235 0.0001470 ENSG00000204869.9 Q6B9Z1 IGFL4 IGFL4 444882 IGF like family member 4 [Source:HGNC Symbol;Acc:HGNC:32931] protein_coding
ENSG00000076864 56.712786 1.063499 0.2519716 4.220709 0.0000244 0.0001523 ENSG00000076864.21 Q5T3T0 RAP1GAP RAP1GAP 5909 RAP1 GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:9858] protein_coding
ENSG00000010438 12.515845 2.332015 0.5526590 4.219627 0.0000245 0.0001529 ENSG00000010438.17 A0A7P0MP65 PRSS3 PRSS3 5646 serine protease 3 [Source:HGNC Symbol;Acc:HGNC:9486] protein_coding
ENSG00000204421 10.729259 4.007754 0.9529851 4.205475 0.0000261 0.0001619 ENSG00000204421.3 O95867 LY6G6C LY6G6C 80740 lymphocyte antigen 6 family member G6C [Source:HGNC Symbol;Acc:HGNC:13936] protein_coding
ENSG00000165646 6.272255 5.533869 1.3193010 4.194546 0.0000273 0.0001689 ENSG00000165646.14 Q05940 SLC18A2 SLC18A2 6571 solute carrier family 18 member A2 [Source:HGNC Symbol;Acc:HGNC:10935] protein_coding
ENSG00000175505 47.226511 1.096800 0.2628999 4.171931 0.0000302 0.0001851 ENSG00000175505.11 Q9UBD9 CLCF1 CLCF1 23529 cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412] protein_coding
ENSG00000092445 47.781757 1.053284 0.2531607 4.160538 0.0000317 0.0001940 ENSG00000092445.12 Q06418 TYRO3 TYRO3 7301 TYRO3 protein tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12446] protein_coding
ENSG00000154277 37.571859 1.279210 0.3084621 4.147056 0.0000337 0.0002046 ENSG00000154277.13 D6R974 UCHL1 UCHL1 7345 ubiquitin C-terminal hydrolase L1 [Source:HGNC Symbol;Acc:HGNC:12513] protein_coding
ENSG00000287927 5.171683 5.525932 1.3405465 4.122149 0.0000375 0.0002262 ENSG00000287927.1 107986954 novel transcript lncRNA
ENSG00000203785 11.013187 3.740426 0.9090469 4.114668 0.0000388 0.0002331 ENSG00000203785.9 P22531 SPRR2E SPRR2E 6704 small proline rich protein 2E [Source:HGNC Symbol;Acc:HGNC:11265] protein_coding
ENSG00000139292 8.565426 2.908739 0.7070645 4.113824 0.0000389 0.0002339 ENSG00000139292.13 O75473 LGR5 LGR5 8549 leucine rich repeat containing G protein-coupled receptor 5 [Source:HGNC Symbol;Acc:HGNC:4504] protein_coding
ENSG00000271856 7.615476 3.313055 0.8056182 4.112438 0.0000392 0.0002352 ENSG00000271856.1 LINC01215 101929623 long intergenic non-protein coding RNA 1215 [Source:HGNC Symbol;Acc:HGNC:49651] lncRNA
ENSG00000156510 16.126953 2.145602 0.5228066 4.104007 0.0000406 0.0002433 ENSG00000156510.13 Q2TB90 HKDC1 HKDC1 80201 hexokinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23302] protein_coding
ENSG00000186792 48.912841 1.050437 0.2577193 4.075895 0.0000458 0.0002718 ENSG00000186792.17 O43820 HYAL3 HYAL3 8372 hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] protein_coding
ENSG00000238266 9.862345 2.539945 0.6245893 4.066585 0.0000477 0.0002817 ENSG00000238266.3 LINC00707 100507127 long intergenic non-protein coding RNA 707 [Source:HGNC Symbol;Acc:HGNC:44691] lncRNA
ENSG00000257594 20.805862 1.788515 0.4418726 4.047581 0.0000517 0.0003041 ENSG00000257594.4 Q8N4A0 GALNT4 GALNT4 8693 polypeptide N-acetylgalactosaminyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:4126] protein_coding
ENSG00000135045 50.350740 1.073287 0.2658248 4.037571 0.0000540 0.0003163 ENSG00000135045.7 Q8IXQ3 C9orf40 C9orf40 55071 chromosome 9 open reading frame 40 [Source:HGNC Symbol;Acc:HGNC:23433] protein_coding
ENSG00000233569 15.896971 2.045801 0.5082129 4.025479 0.0000569 0.0003311 ENSG00000233569.2 101928797 novel transcript lncRNA
ENSG00000248587 8.426787 3.551202 0.8858435 4.008837 0.0000610 0.0003530 ENSG00000248587.8 GDNF-AS1 NA GDNF antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43592] lncRNA
ENSG00000117407 27.882982 1.276704 0.3193854 3.997379 0.0000640 0.0003686 ENSG00000117407.17 Q5T4W7 ARTN ARTN 9048 artemin [Source:HGNC Symbol;Acc:HGNC:727] protein_coding
ENSG00000186567 35.111180 1.196811 0.3004501 3.983393 0.0000679 0.0003884 ENSG00000186567.14 Q7Z692 CEACAM19 CEACAM19 56971 CEA cell adhesion molecule 19 [Source:HGNC Symbol;Acc:HGNC:31951] protein_coding
ENSG00000145911 43.233144 1.067229 0.2681360 3.980178 0.0000689 0.0003929 ENSG00000145911.6 O15049 N4BP3 N4BP3 23138 NEDD4 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:29852] protein_coding
ENSG00000103254 35.552760 1.141589 0.2870198 3.977388 0.0000697 0.0003969 ENSG00000103254.10 Q9BQD7 ANTKMT ANTKMT 65990 adenine nucleotide translocase lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:14152] protein_coding
ENSG00000124256 8.249823 3.444411 0.8662611 3.976181 0.0000700 0.0003987 ENSG00000124256.15 Q9H171 ZBP1 ZBP1 81030 Z-DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:16176] protein_coding
ENSG00000177300 18.052806 1.976285 0.4972795 3.974194 0.0000706 0.0004017 ENSG00000177300.7 Q8N7P3 CLDN22 CLDN22 53842 claudin 22 [Source:HGNC Symbol;Acc:HGNC:2044] protein_coding
ENSG00000114948 46.510615 1.037704 0.2627796 3.948952 0.0000785 0.0004425 ENSG00000114948.13 O75077 ADAM23 ADAM23 8745 ADAM metallopeptidase domain 23 [Source:HGNC Symbol;Acc:HGNC:202] protein_coding
ENSG00000070669 20.881688 1.499143 0.3832218 3.911945 0.0000916 0.0005110 ENSG00000070669.17 F8WEJ5 ASNS ASNS 440 asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:HGNC:753] protein_coding
ENSG00000235513 19.035757 1.611953 0.4122996 3.909664 0.0000924 0.0005156 ENSG00000235513.2 L3MBTL2-AS1 NA L3MBTL2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40847] lncRNA
ENSG00000196408 40.340224 1.121142 0.2875973 3.898304 0.0000969 0.0005379 ENSG00000196408.12 Q8NFA2 NOXO1 NOXO1 124056 NADPH oxidase organizer 1 [Source:HGNC Symbol;Acc:HGNC:19404] protein_coding
ENSG00000160200 7.678611 2.940814 0.7579210 3.880106 0.0001044 0.0005768 ENSG00000160200.18 P35520 CBS CBS 102724560 cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] protein_coding
ENSG00000165091 13.175931 2.165088 0.5590654 3.872693 0.0001076 0.0005935 ENSG00000165091.18 A0A2R8YDA3 TMC1 TMC1 117531 transmembrane channel like 1 [Source:HGNC Symbol;Acc:HGNC:16513] protein_coding
ENSG00000135960 39.880274 1.152490 0.2977917 3.870122 0.0001088 0.0005993 ENSG00000135960.10 Q9UNE0 EDAR EDAR 10913 ectodysplasin A receptor [Source:HGNC Symbol;Acc:HGNC:2895] protein_coding
ENSG00000111981 24.595593 1.408745 0.3641495 3.868589 0.0001095 0.0006027 ENSG00000111981.5 Q9BZM6 ULBP1 ULBP1 80329 UL16 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:14893] protein_coding
ENSG00000283930 19.564458 1.870314 0.4844464 3.860724 0.0001131 0.0006208 ENSG00000283930.1 A0A1W2PQ67 PLD5P1 PLD5P1 NA PLD5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:55072] protein_coding
ENSG00000254951 15.961184 1.868458 0.4888459 3.822182 0.0001323 0.0007151 ENSG00000254951.7 283299 novel transcript, sense overlapping OR5P2, OR5P3 and OR5P1P lncRNA
ENSG00000205057 6.403499 3.708031 0.9755229 3.801070 0.0001441 0.0007742 ENSG00000205057.6 CLLU1-AS1 574016 CLLU1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:24070] lncRNA
ENSG00000148053 30.647476 1.358380 0.3594884 3.778649 0.0001577 0.0008411 ENSG00000148053.18 A0A8I5KUZ1 NTRK2 NTRK2 4915 neurotrophic receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:8032] protein_coding
ENSG00000008735 22.743388 1.446062 0.3828257 3.777338 0.0001585 0.0008449 ENSG00000008735.14 Q13387 MAPK8IP2 MAPK8IP2 23542 mitogen-activated protein kinase 8 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:6883] protein_coding
ENSG00000286042 27.827205 1.571499 0.4164421 3.773633 0.0001609 0.0008571 ENSG00000286042.1 LCAL1 80078 lung cancer associated lncRNA 1 [Source:HGNC Symbol;Acc:HGNC:25837] lncRNA
ENSG00000118432 12.410747 2.024255 0.5408002 3.743073 0.0001818 0.0009581 ENSG00000118432.13 F8W908 CNR1 CNR1 1268 cannabinoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:2159] protein_coding
ENSG00000138316 13.416514 1.940078 0.5193748 3.735411 0.0001874 0.0009864 ENSG00000138316.11 Q8WXS8 ADAMTS14 ADAMTS14 140766 ADAM metallopeptidase with thrombospondin type 1 motif 14 [Source:HGNC Symbol;Acc:HGNC:14899] protein_coding
ENSG00000128578 29.466740 1.267005 0.3395285 3.731659 0.0001902 0.0010002 ENSG00000128578.10 Q9ULQ0 STRIP2 STRIP2 57464 striatin interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:22209] protein_coding
ENSG00000245213 52.996350 1.024787 0.2749893 3.726642 0.0001940 0.0010177 ENSG00000245213.7 GALNT7-DT 101930370 GALNT7 divergent transcript [Source:HGNC Symbol;Acc:HGNC:55604] lncRNA
ENSG00000157111 31.834325 1.128077 0.3036019 3.715646 0.0002027 0.0010586 ENSG00000157111.13 Q8WVE6 TMEM171 TMEM171 134285 transmembrane protein 171 [Source:HGNC Symbol;Acc:HGNC:27031] protein_coding
ENSG00000124019 5.652396 4.844428 1.3116993 3.693246 0.0002214 0.0011502 ENSG00000124019.10 Q9H5Z6 FAM124B FAM124B 79843 family with sequence similarity 124 member B [Source:HGNC Symbol;Acc:HGNC:26224] protein_coding
ENSG00000115590 9.274236 3.208442 0.8699317 3.688154 0.0002259 0.0011714 ENSG00000115590.14 P27930 IL1R2 IL1R2 7850 interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994] protein_coding
ENSG00000120907 4.390701 5.018656 1.3642846 3.678599 0.0002345 0.0012109 ENSG00000120907.18 P35348 ADRA1A ADRA1A 148 adrenoceptor alpha 1A [Source:HGNC Symbol;Acc:HGNC:277] protein_coding
ENSG00000183378 15.701056 1.860972 0.5059094 3.678468 0.0002346 0.0012112 ENSG00000183378.13 A0A087X1V8 OVCH2 OVCH2 341277 ovochymase 2 [Source:HGNC Symbol;Acc:HGNC:29970] protein_coding
ENSG00000151490 17.514277 2.457470 0.6684086 3.676599 0.0002364 0.0012170 ENSG00000151490.15 Q16827 PTPRO PTPRO 5800 protein tyrosine phosphatase receptor type O [Source:HGNC Symbol;Acc:HGNC:9678] protein_coding
ENSG00000284644 12.781003 2.161526 0.5933786 3.642744 0.0002697 0.0013694 ENSG00000284644.1 NA novel transcript, antisense to OR2A1 and ARHGEF5 lncRNA
ENSG00000133116 17.273430 1.599936 0.4396564 3.639060 0.0002736 0.0013864 ENSG00000133116.8 Q9UEF7 KL KL 9365 klotho [Source:HGNC Symbol;Acc:HGNC:6344] protein_coding
ENSG00000087303 28.829676 1.336075 0.3711848 3.599487 0.0003188 0.0015877 ENSG00000087303.19 Q14112 NID2 NID2 22795 nidogen 2 [Source:HGNC Symbol;Acc:HGNC:13389] protein_coding
ENSG00000105880 8.739451 2.910397 0.8113041 3.587307 0.0003341 0.0016577 ENSG00000105880.7 P56178 DLX5 DLX5 1749 distal-less homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2918] protein_coding
ENSG00000170608 10.559893 2.854585 0.7964854 3.583977 0.0003384 0.0016759 ENSG00000170608.3 M0QZW5 FOXA3 FOXA3 3171 forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023] protein_coding
ENSG00000167916 17.706117 1.675649 0.4713507 3.554994 0.0003780 0.0018532 ENSG00000167916.5 Q2M2I5 KRT24 KRT24 192666 keratin 24 [Source:HGNC Symbol;Acc:HGNC:18527] protein_coding
ENSG00000163216 148.187531 1.559522 0.4388447 3.553699 0.0003799 0.0018605 ENSG00000163216.7 P22532 SPRR2D SPRR2D 6703 small proline rich protein 2D [Source:HGNC Symbol;Acc:HGNC:11264] protein_coding
ENSG00000170356 30.168817 1.205688 0.3405524 3.540389 0.0003995 0.0019484 ENSG00000170356.10 OR2A20P 401428 olfactory receptor family 2 subfamily A member 20 pseudogene [Source:HGNC Symbol;Acc:HGNC:15413] transcribed_unprocessed_pseudogene
ENSG00000153993 35.877673 1.040638 0.2939582 3.540087 0.0004000 0.0019498 ENSG00000153993.14 C9JYT6 SEMA3D SEMA3D 223117 semaphorin 3D [Source:HGNC Symbol;Acc:HGNC:10726] protein_coding
ENSG00000107518 26.034677 1.555815 0.4414207 3.524563 0.0004242 0.0020563 ENSG00000107518.18 Q5VV63 ATRNL1 ATRNL1 26033 attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063] protein_coding
ENSG00000102962 23.156425 1.367044 0.3882802 3.520766 0.0004303 0.0020820 ENSG00000102962.5 O00626 CCL22 CCL22 6367 C-C motif chemokine ligand 22 [Source:HGNC Symbol;Acc:HGNC:10621] protein_coding
ENSG00000250986 4.172792 4.723881 1.3432996 3.516625 0.0004371 0.0021092 ENSG00000250986.1 LINC02600 NA long intergenic non-protein coding RNA 2600 [Source:HGNC Symbol;Acc:HGNC:53177] lncRNA
ENSG00000278991 66.237367 1.057175 0.3009952 3.512264 0.0004443 0.0021411 ENSG00000278991.1 NA TEC TEC
ENSG00000144843 26.301671 1.246632 0.3549930 3.511707 0.0004452 0.0021451 ENSG00000144843.12 P54922 ADPRH ADPRH 141 ADP-ribosylarginine hydrolase [Source:HGNC Symbol;Acc:HGNC:269] protein_coding
ENSG00000115165 7.385393 3.106189 0.8907306 3.487237 0.0004880 0.0023248 ENSG00000115165.10 O60759 CYTIP CYTIP 9595 cytohesin 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:9506] protein_coding
ENSG00000177096 40.755625 1.004345 0.2881031 3.486061 0.0004902 0.0023335 ENSG00000177096.9 Q6ICB4 PHETA2 PHETA2 150368 PH domain containing endocytic trafficking adaptor 2 [Source:HGNC Symbol;Acc:HGNC:27161] protein_coding
ENSG00000099251 32.300115 1.444206 0.4147757 3.481898 0.0004979 0.0023650 ENSG00000099251.15 HSD17B7P2 NA hydroxysteroid 17-beta dehydrogenase 7 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28120] transcribed_unprocessed_pseudogene
ENSG00000288695 20.700774 1.534179 0.4406794 3.481394 0.0004988 0.0023678 ENSG00000288695.1 NA novel protein, SRD5A3-RP11-177J6.1 readthrough protein_coding
ENSG00000233588 9.015725 2.654340 0.7633163 3.477378 0.0005063 0.0023991 ENSG00000233588.1 CYP51A1P2 NA cytochrome P450 family 51 subfamily A member 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:20251] processed_pseudogene
ENSG00000163995 16.725364 1.557126 0.4506679 3.455152 0.0005500 0.0025823 ENSG00000163995.22 Q6H8Q1 ABLIM2 ABLIM2 84448 actin binding LIM protein family member 2 [Source:HGNC Symbol;Acc:HGNC:19195] protein_coding
ENSG00000279294 15.466086 1.798536 0.5216048 3.448081 0.0005646 0.0026424 ENSG00000279294.1 NA novel transcript TEC
ENSG00000285763 13.156407 1.761324 0.5108956 3.447522 0.0005658 0.0026460 ENSG00000285763.1 NA novel transcript, antisense to C6orf52 lncRNA
ENSG00000175920 22.295691 1.276146 0.3709861 3.439876 0.0005820 0.0027169 ENSG00000175920.18 A0A2R8Y701 DOK7 DOK7 285489 docking protein 7 [Source:HGNC Symbol;Acc:HGNC:26594] protein_coding
ENSG00000185352 6.424647 3.385124 0.9859889 3.433228 0.0005964 0.0027704 ENSG00000185352.10 Q8IZP7 HS6ST3 HS6ST3 266722 heparan sulfate 6-O-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:19134] protein_coding
ENSG00000171303 6.902379 2.408109 0.7033160 3.423935 0.0006172 0.0028577 ENSG00000171303.8 O14649 KCNK3 KCNK3 3777 potassium two pore domain channel subfamily K member 3 [Source:HGNC Symbol;Acc:HGNC:6278] protein_coding
ENSG00000206828 26.864395 1.197432 0.3504600 3.416745 0.0006337 0.0029269 ENSG00000206828.1 RNVU1-30 124904627 RNA, variant U1 small nuclear 30 [Source:HGNC Symbol;Acc:HGNC:54434] snRNA
ENSG00000116852 13.263094 1.736418 0.5091154 3.410657 0.0006481 0.0029870 ENSG00000116852.15 O75037 KIF21B KIF21B 23046 kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442] protein_coding
ENSG00000204889 15.991223 1.479485 0.4348350 3.402404 0.0006680 0.0030719 ENSG00000204889.11 Q6A162 KRT40 KRT40 125115 keratin 40 [Source:HGNC Symbol;Acc:HGNC:26707] protein_coding
ENSG00000272941 11.521752 1.766714 0.5199380 3.397933 0.0006790 0.0031148 ENSG00000272941.1 NA novel transcript, antisense to C7orf49 lncRNA
ENSG00000244094 9.743436 2.520850 0.7450157 3.383620 0.0007154 0.0032668 ENSG00000244094.2 Q96RM1 SPRR2F SPRR2F 6705 small proline rich protein 2F [Source:HGNC Symbol;Acc:HGNC:11266] protein_coding
ENSG00000163568 22.944102 1.221604 0.3616540 3.377827 0.0007306 0.0033289 ENSG00000163568.16 O14862 AIM2 AIM2 9447 absent in melanoma 2 [Source:HGNC Symbol;Acc:HGNC:357] protein_coding
ENSG00000154548 16.072852 1.637952 0.4856852 3.372456 0.0007450 0.0033846 ENSG00000154548.9 Q8WXF0 SRSF12 SRSF12 135295 serine and arginine rich splicing factor 12 [Source:HGNC Symbol;Acc:HGNC:21220] protein_coding
ENSG00000121335 9.750543 4.443506 1.3241507 3.355741 0.0007915 0.0035752 ENSG00000121335.12 P02812 PRB2 PRB2 653247 proline rich protein BstNI subfamily 2 [Source:HGNC Symbol;Acc:HGNC:9338] protein_coding
ENSG00000167992 23.552460 1.375135 0.4100973 3.353192 0.0007989 0.0036034 ENSG00000167992.14 B4DY31 VWCE VWCE 220001 von Willebrand factor C and EGF domains [Source:HGNC Symbol;Acc:HGNC:26487] protein_coding
ENSG00000244479 6.171695 3.327065 0.9941658 3.346589 0.0008181 0.0036855 ENSG00000244479.7 OR2A1-AS1 NA OR2A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49168] lncRNA
ENSG00000134588 4.723098 4.568000 1.3693043 3.336001 0.0008499 0.0038068 ENSG00000134588.13 Q9BXU7 USP26 USP26 83844 ubiquitin specific peptidase 26 [Source:HGNC Symbol;Acc:HGNC:13485] protein_coding
ENSG00000166924 16.939107 1.722857 0.5219189 3.301004 0.0009634 0.0042568 ENSG00000166924.9 C9JS30 NYAP1 NYAP1 222950 neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 [Source:HGNC Symbol;Acc:HGNC:22009] protein_coding
ENSG00000179546 13.783441 1.868871 0.5680410 3.290029 0.0010018 0.0044101 ENSG00000179546.5 P28221 HTR1D HTR1D 3352 5-hydroxytryptamine receptor 1D [Source:HGNC Symbol;Acc:HGNC:5289] protein_coding
ENSG00000135643 24.283800 1.183580 0.3606873 3.281458 0.0010327 0.0045352 ENSG00000135643.5 Q86W47 KCNMB4 KCNMB4 27345 potassium calcium-activated channel subfamily M regulatory beta subunit 4 [Source:HGNC Symbol;Acc:HGNC:6289] protein_coding
ENSG00000119686 21.046513 1.317033 0.4016031 3.279441 0.0010401 0.0045651 ENSG00000119686.10 G3V391 FLVCR2 FLVCR2 55640 FLVCR heme transporter 2 [Source:HGNC Symbol;Acc:HGNC:20105] protein_coding
ENSG00000237988 21.354011 1.320475 0.4041766 3.267074 0.0010867 0.0047497 ENSG00000237988.6 A0A2R8Y4D9 OR2I1P OR2I1P 442197 olfactory receptor family 2 subfamily I member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:8258] protein_coding
ENSG00000093009 16.549652 1.597417 0.4899494 3.260371 0.0011127 0.0048488 ENSG00000093009.11 O75419 CDC45 CDC45 8318 cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739] protein_coding
ENSG00000221887 11.736873 1.960388 0.6021918 3.255421 0.0011322 0.0049225 ENSG00000221887.6 P0C7T4 HMSD HMSD 284293 histocompatibility minor serpin domain containing [Source:HGNC Symbol;Acc:HGNC:23037] protein_coding
ENSG00000188573 7.477348 2.302583 0.7145178 3.222570 0.0012705 0.0054580 ENSG00000188573.8 A6NHQ2 FBLL1 FBLL1 345630 fibrillarin like 1 [Source:HGNC Symbol;Acc:HGNC:35458] protein_coding
ENSG00000159640 18.505798 1.428612 0.4472601 3.194142 0.0014025 0.0059684 ENSG00000159640.17 P12821 ACE ACE 1636 angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707] protein_coding
ENSG00000244247 3.301485 4.619080 1.4461642 3.194022 0.0014031 0.0059696 ENSG00000244247.2 LINC01995 105374244 long intergenic non-protein coding RNA 1995 [Source:HGNC Symbol;Acc:HGNC:52828] lncRNA
ENSG00000234380 17.836085 1.418746 0.4460764 3.180501 0.0014702 0.0062279 ENSG00000234380.3 LINC01426 100506385 long intergenic non-protein coding RNA 1426 [Source:HGNC Symbol;Acc:HGNC:50734] lncRNA
ENSG00000148798 24.148256 1.156141 0.3638650 3.177390 0.0014861 0.0062867 ENSG00000148798.11 Q16352 INA INA 9118 internexin neuronal intermediate filament protein alpha [Source:HGNC Symbol;Acc:HGNC:6057] protein_coding
ENSG00000181444 24.174885 1.187191 0.3738946 3.175202 0.0014973 0.0063296 ENSG00000181444.13 C9JAX3 ZNF467 ZNF467 168544 zinc finger protein 467 [Source:HGNC Symbol;Acc:HGNC:23154] protein_coding
ENSG00000230533 29.693138 1.090888 0.3438691 3.172393 0.0015119 0.0063832 ENSG00000230533.5 LINC03004 102723649 long intergenic non-protein coding RNA 3004 [Source:HGNC Symbol;Acc:HGNC:56128] lncRNA
ENSG00000005108 8.541624 2.249360 0.7139912 3.150402 0.0016305 0.0068172 ENSG00000005108.17 Q9UPZ6 THSD7A THSD7A 221981 thrombospondin type 1 domain containing 7A [Source:HGNC Symbol;Acc:HGNC:22207] protein_coding
ENSG00000164949 18.239389 1.604318 0.5125584 3.130021 0.0017479 0.0072680 ENSG00000164949.8 P55040 GEM GEM 2669 GTP binding protein overexpressed in skeletal muscle [Source:HGNC Symbol;Acc:HGNC:4234] protein_coding
ENSG00000136404 12.495883 1.532848 0.4920774 3.115054 0.0018391 0.0076097 ENSG00000136404.16 Q9BZW5 TM6SF1 TM6SF1 53346 transmembrane 6 superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:11860] protein_coding
ENSG00000186603 5.942231 2.886573 0.9267986 3.114563 0.0018422 0.0076179 ENSG00000186603.7 Q96IR7 HPDL HPDL 84842 4-hydroxyphenylpyruvate dioxygenase like [Source:HGNC Symbol;Acc:HGNC:28242] protein_coding
ENSG00000269919 5.239927 3.646810 1.1778489 3.096161 0.0019604 0.0080575 ENSG00000269919.1 NA novel transcript, sense intronic to PRDM1 lncRNA
ENSG00000287879 4.729150 3.637709 1.1868090 3.065118 0.0021758 0.0088505 ENSG00000287879.1 NA novel transcript lncRNA
ENSG00000088538 24.190015 1.102897 0.3598357 3.065003 0.0021767 0.0088514 ENSG00000088538.13 Q8IZD9 DOCK3 DOCK3 1795 dedicator of cytokinesis 3 [Source:HGNC Symbol;Acc:HGNC:2989] protein_coding
ENSG00000243004 25.538168 1.158206 0.3808045 3.041473 0.0023542 0.0095115 ENSG00000243004.7 NA novel transcript, sense overlapping to MACC1 lncRNA
ENSG00000136274 13.567995 1.583934 0.5209136 3.040684 0.0023604 0.0095280 ENSG00000136274.9 O15069 NACAD NACAD 23148 NAC alpha domain containing [Source:HGNC Symbol;Acc:HGNC:22196] protein_coding
ENSG00000065675 17.283015 1.345806 0.4430750 3.037422 0.0023861 0.0096088 ENSG00000065675.16 Q04759 PRKCQ PRKCQ 5588 protein kinase C theta [Source:HGNC Symbol;Acc:HGNC:9410] protein_coding
ENSG00000260528 12.405697 1.545459 0.5096066 3.032650 0.0024242 0.0097389 ENSG00000260528.6 FAM157C NA family with sequence similarity 157 member C [Source:HGNC Symbol;Acc:HGNC:34081] lncRNA
ENSG00000112541 18.535731 1.235829 0.4078226 3.030311 0.0024430 0.0098030 ENSG00000112541.19 A0A7I2V301 PDE10A PDE10A 90632 phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772] protein_coding
ENSG00000189325 12.379934 1.534327 0.5075775 3.022844 0.0025041 0.0100254 ENSG00000189325.7 P0C671 BNIP5 BNIP5 389384 BCL2 interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:33769] protein_coding
ENSG00000213398 25.014343 1.127236 0.3737696 3.015857 0.0025625 0.0102240 ENSG00000213398.8 P04180 LCAT LCAT 3931 lecithin-cholesterol acyltransferase [Source:HGNC Symbol;Acc:HGNC:6522] protein_coding
ENSG00000275552 14.639784 1.814266 0.6018579 3.014442 0.0025745 0.0102637 ENSG00000275552.1 NA novel transcript, antisense ABHD4 lncRNA
ENSG00000186517 18.683115 1.265306 0.4211934 3.004099 0.0026637 0.0105756 ENSG00000186517.14 E9PLA4 ARHGAP30 ARHGAP30 257106 Rho GTPase activating protein 30 [Source:HGNC Symbol;Acc:HGNC:27414] protein_coding
ENSG00000228477 16.351264 1.512845 0.5050780 2.995270 0.0027420 0.0108358 ENSG00000228477.1 NA ribosomal protein S2 (RPS2) pseudogene processed_pseudogene
ENSG00000241717 4.597056 4.040159 1.3509720 2.990557 0.0027847 0.0109873 ENSG00000241717.1 VWFP1 NA von Willebrand factor pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:12727] transcribed_unprocessed_pseudogene
ENSG00000289341 6.844261 2.202054 0.7403928 2.974170 0.0029378 0.0115177 ENSG00000289341.2 NA novel transcript lncRNA
ENSG00000277610 22.993833 1.166252 0.3933310 2.965065 0.0030262 0.0118072 ENSG00000277610.1 RNVU1-4 101954268 RNA, variant U1 small nuclear 4 [Source:HGNC Symbol;Acc:HGNC:48312] snRNA
ENSG00000188676 5.470686 3.067338 1.0377625 2.955723 0.0031194 0.0121149 ENSG00000188676.15 IDO2 169355 indoleamine 2,3-dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:27269] protein_coding
ENSG00000246350 26.377402 1.070565 0.3622619 2.955224 0.0031244 0.0121298 ENSG00000246350.1 ZBED9-AS1 NA ZBED9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:55596] lncRNA
ENSG00000125740 22.315660 1.145142 0.3881147 2.950525 0.0031723 0.0123017 ENSG00000125740.15 K7ERZ8 FOSB FOSB 2354 FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797] protein_coding
ENSG00000275302 8.240859 1.995504 0.6775243 2.945288 0.0032265 0.0124834 ENSG00000275302.2 P13236 CCL4 CCL4 6351 C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630] protein_coding
ENSG00000251194 12.840119 1.465366 0.4978366 2.943468 0.0032456 0.0125427 ENSG00000251194.2 NA novel transcript lncRNA
ENSG00000228124 13.069596 1.468549 0.4994504 2.940330 0.0032786 0.0126559 ENSG00000228124.1 MDN1-AS1 NA MDN1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40837] lncRNA
ENSG00000169122 6.897346 2.170514 0.7407783 2.930045 0.0033891 0.0130108 ENSG00000169122.12 A0A024R7V5 C8orf72 FAM110B 90362 family with sequence similarity 110 member B [Source:HGNC Symbol;Acc:HGNC:28587] protein_coding
ENSG00000185303 6.381847 2.407506 0.8222623 2.927904 0.0034125 0.0130883 ENSG00000185303.17 R4GMN3 SFTPA2 SFTPA2 729238 surfactant protein A2 [Source:HGNC Symbol;Acc:HGNC:10799] protein_coding
ENSG00000172554 10.405325 1.690797 0.5794923 2.917722 0.0035260 0.0134674 ENSG00000172554.12 A0A0G2JS85 SNTG2 SNTG2 54221 syntrophin gamma 2 [Source:HGNC Symbol;Acc:HGNC:13741] protein_coding
ENSG00000274322 5.867325 2.469698 0.8579512 2.878599 0.0039945 0.0150001 ENSG00000274322.1 NA novel protein protein_coding
ENSG00000109158 3.429093 4.201612 1.4614100 2.875040 0.0040398 0.0151478 ENSG00000109158.11 D6R924 GABRA4 GABRA4 2557 gamma-aminobutyric acid type A receptor subunit alpha4 [Source:HGNC Symbol;Acc:HGNC:4078] protein_coding
ENSG00000205076 4.027817 3.578180 1.2472909 2.868762 0.0041208 0.0153949 ENSG00000205076.5 P47929 LGALS7 LGALS7 653499 galectin 7 [Source:HGNC Symbol;Acc:HGNC:6568] protein_coding
ENSG00000287941 6.372786 2.696222 0.9402214 2.867646 0.0041354 0.0154408 ENSG00000287941.1 NA novel transcript lncRNA
ENSG00000112137 22.375278 1.031237 0.3600211 2.864379 0.0041783 0.0155837 ENSG00000112137.19 A0A6Q8PGC2 PHACTR1 PHACTR1 221692 phosphatase and actin regulator 1 [Source:HGNC Symbol;Acc:HGNC:20990] protein_coding
ENSG00000254560 8.774984 1.707785 0.5980113 2.855773 0.0042932 0.0159597 ENSG00000254560.6 BBOX1-AS1 103695435 BBOX1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50700] lncRNA
ENSG00000100565 3.199095 4.197629 1.4768846 2.842219 0.0044801 0.0165755 ENSG00000100565.16 Q0VAA2 LRRC74A LRRC74A 145497 leucine rich repeat containing 74A [Source:HGNC Symbol;Acc:HGNC:23346] protein_coding
ENSG00000123496 3.471592 3.139269 1.1069187 2.836043 0.0045676 0.0168656 ENSG00000123496.8 Q14627 IL13RA2 IL13RA2 3598 interleukin 13 receptor subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:5975] protein_coding
ENSG00000170965 3.180913 3.940450 1.3945480 2.825611 0.0047191 0.0173679 ENSG00000170965.10 Q9HBJ0 PLAC1 PLAC1 10761 placenta enriched 1 [Source:HGNC Symbol;Acc:HGNC:9044] protein_coding
ENSG00000198650 12.231587 1.678796 0.5956184 2.818576 0.0048237 0.0177146 ENSG00000198650.11 P17735 TAT TAT 6898 tyrosine aminotransferase [Source:HGNC Symbol;Acc:HGNC:11573] protein_coding
ENSG00000278952 14.596015 1.818697 0.6509956 2.793716 0.0052106 0.0189606 ENSG00000278952.1 NA TEC TEC
ENSG00000124143 26.956559 1.058429 0.3799326 2.785833 0.0053390 0.0193482 ENSG00000124143.11 ARHGAP40 343578 Rho GTPase activating protein 40 [Source:HGNC Symbol;Acc:HGNC:16226] protein_coding
ENSG00000249378 14.397426 1.228730 0.4422003 2.778673 0.0054581 0.0196885 ENSG00000249378.8 LINC01060 401164 long intergenic non-protein coding RNA 1060 [Source:HGNC Symbol;Acc:HGNC:49081] lncRNA
ENSG00000274114 16.515631 1.223102 0.4408008 2.774727 0.0055248 0.0199148 ENSG00000274114.3 ALOX15P1 NA arachidonate 15-lipoxygenase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13742] transcribed_unprocessed_pseudogene
ENSG00000222429 4.380981 3.604668 1.3006629 2.771408 0.0055814 0.0200762 ENSG00000222429.1 RNU6-955P NA RNA, U6 small nuclear 955, pseudogene [Source:HGNC Symbol;Acc:HGNC:47918] snRNA
ENSG00000235448 7.499587 1.933045 0.6990462 2.765260 0.0056877 0.0204115 ENSG00000235448.3 LURAP1L-AS1 NA LURAP1L antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49761] lncRNA
ENSG00000166741 8.903737 1.720696 0.6223514 2.764831 0.0056952 0.0204348 ENSG00000166741.9 P40261 NNMT NNMT 4837 nicotinamide N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:7861] protein_coding
ENSG00000225964 9.388559 1.587022 0.5745444 2.762227 0.0057408 0.0205876 ENSG00000225964.6 NRIR NA negative regulator of interferon response [Source:HGNC Symbol;Acc:HGNC:51269] lncRNA
ENSG00000160447 15.409973 1.281073 0.4654917 2.752084 0.0059217 0.0211504 ENSG00000160447.7 Q6P5Z2 PKN3 PKN3 29941 protein kinase N3 [Source:HGNC Symbol;Acc:HGNC:17999] protein_coding
ENSG00000225339 12.232890 1.474823 0.5381777 2.740402 0.0061364 0.0217697 ENSG00000225339.4 NA novel transcript, antisense to C6orf1 lncRNA
ENSG00000158517 3.996887 2.946725 1.0773280 2.735216 0.0062339 0.0220663 ENSG00000158517.16 P14598 NCF1 NCF1 653361 neutrophil cytosolic factor 1 [Source:HGNC Symbol;Acc:HGNC:7660] protein_coding
ENSG00000251537 23.484716 1.040708 0.3830317 2.717028 0.0065871 0.0231644 ENSG00000251537.4 NA novel tripartite motif-containing 16 (TRIM16) and CMT1A duplicated region transcript 1 (CDRT1) protein protein_coding
ENSG00000239593 6.210092 2.225323 0.8195803 2.715198 0.0066236 0.0232733 ENSG00000239593.1 NA novel transcript lncRNA
ENSG00000288900 6.652089 1.951486 0.7197548 2.711321 0.0067016 0.0234896 ENSG00000288900.1 NA novel transcript lncRNA
ENSG00000283646 4.472554 2.910989 1.0748590 2.708252 0.0067639 0.0236875 ENSG00000283646.2 LINC02009 105377068 long intergenic non-protein coding RNA 2009 [Source:HGNC Symbol;Acc:HGNC:52845] lncRNA
ENSG00000225206 3.717189 2.858002 1.0611004 2.693432 0.0070721 0.0246563 ENSG00000225206.12 MIR137HG 400765 MIR137 host gene [Source:HGNC Symbol;Acc:HGNC:42871] lncRNA
ENSG00000197921 16.201431 1.243306 0.4641052 2.678932 0.0073857 0.0256093 ENSG00000197921.6 Q5TA89 HES5 HES5 388585 hes family bHLH transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:19764] protein_coding
ENSG00000183303 9.007228 1.644547 0.6139896 2.678461 0.0073961 0.0256325 ENSG00000183303.3 Q8WZ92 OR5P2 OR5P2 120065 olfactory receptor family 5 subfamily P member 2 [Source:HGNC Symbol;Acc:HGNC:14783] protein_coding
ENSG00000139269 4.505770 2.476305 0.9327322 2.654894 0.0079333 0.0272245 ENSG00000139269.3 P58166 INHBE INHBE 83729 inhibin subunit beta E [Source:HGNC Symbol;Acc:HGNC:24029] protein_coding
ENSG00000249345 4.264107 2.917436 1.1019847 2.647438 0.0081104 0.0277760 ENSG00000249345.8 LINC02405 101927592 long intergenic non-protein coding RNA 2405 [Source:HGNC Symbol;Acc:HGNC:53333] lncRNA
ENSG00000154096 3.004896 3.434223 1.2985927 2.644573 0.0081794 0.0279713 ENSG00000154096.14 P04216 THY1 THY1 7070 Thy-1 cell surface antigen [Source:HGNC Symbol;Acc:HGNC:11801] protein_coding
ENSG00000284646 3.599700 3.687560 1.3987020 2.636416 0.0083787 0.0285598 ENSG00000284646.1 NA novel transcript lncRNA
ENSG00000270640 9.258662 1.554179 0.5896950 2.635564 0.0083998 0.0286172 ENSG00000270640.1 NA novel transcript, sense intronic to FOSL2 lncRNA
ENSG00000276107 7.728070 1.766800 0.6704826 2.635116 0.0084108 0.0286454 ENSG00000276107.1 THBS1-IT1 NA THBS1 intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:55225] lncRNA
ENSG00000123610 2.999699 3.808975 1.4474164 2.631569 0.0084992 0.0289074 ENSG00000123610.5 P98066 TNFAIP6 TNFAIP6 7130 TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898] protein_coding
ENSG00000164037 11.828630 1.603000 0.6093107 2.630842 0.0085174 0.0289645 ENSG00000164037.17 H0Y9Z0 SLC9B1 SLC9B1 150159 solute carrier family 9 member B1 [Source:HGNC Symbol;Acc:HGNC:24244] protein_coding
ENSG00000075790 19.424558 1.059474 0.4029499 2.629294 0.0085562 0.0290772 ENSG00000075790.12 F8WDG1 BCAP29 BCAP29 55973 B cell receptor associated protein 29 [Source:HGNC Symbol;Acc:HGNC:24131] protein_coding
ENSG00000101210 22.285947 1.050361 0.4049208 2.593990 0.0094869 0.0317774 ENSG00000101210.14 Q05639 EEF1A2 EEF1A2 1917 eukaryotic translation elongation factor 1 alpha 2 [Source:HGNC Symbol;Acc:HGNC:3192] protein_coding
ENSG00000199879 11.669083 1.424442 0.5535836 2.573129 0.0100784 0.0334442 ENSG00000199879.1 RNVU1-22 NA RNA, variant U1 small nuclear 22 [Source:HGNC Symbol;Acc:HGNC:48462] snRNA
ENSG00000231185 3.990664 2.765093 1.0760835 2.569590 0.0101819 0.0337436 ENSG00000231185.9 SPRY4-AS1 101926941 SPRY4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:53465] lncRNA
ENSG00000286964 12.160545 1.403100 0.5466600 2.566677 0.0102678 0.0340006 ENSG00000286964.1 NA novel transcript lncRNA
ENSG00000288969 5.867381 2.104460 0.8231255 2.556669 0.0105680 0.0348978 ENSG00000288969.1 NA novel transcript, sense intronic to HRH1 lncRNA
ENSG00000169750 18.573976 1.201413 0.4700757 2.555786 0.0105948 0.0349752 ENSG00000169750.9 P60763 RAC3 RAC3 5881 Rac family small GTPase 3 [Source:HGNC Symbol;Acc:HGNC:9803] protein_coding
ENSG00000196711 12.596340 1.490735 0.5841324 2.552050 0.0107091 0.0352664 ENSG00000196711.9 Q6UXT8 ALKAL1 ALKAL1 389658 ALK and LTK ligand 1 [Source:HGNC Symbol;Acc:HGNC:33775] protein_coding
ENSG00000165511 20.757160 1.042646 0.4103588 2.540817 0.0110594 0.0362203 ENSG00000165511.6 ZNF22-AS1 220979 ZNF22 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:23509] lncRNA
ENSG00000173175 5.868261 2.230478 0.8798664 2.535019 0.0112441 0.0367069 ENSG00000173175.16 A0A8V8TP58 ADCY5 ADCY5 111 adenylate cyclase 5 [Source:HGNC Symbol;Acc:HGNC:236] protein_coding
ENSG00000162882 10.453989 1.466802 0.5796977 2.530287 0.0113969 0.0371580 ENSG00000162882.15 P46952 HAAO HAAO 23498 3-hydroxyanthranilate 3,4-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4796] protein_coding
ENSG00000253315 14.933323 1.200010 0.4743233 2.529941 0.0114082 0.0371768 ENSG00000253315.1 LINC01932 105377682 long intergenic non-protein coding RNA 1932 [Source:HGNC Symbol;Acc:HGNC:52755] lncRNA
ENSG00000270210 14.383650 1.131054 0.4494516 2.516520 0.0118520 0.0384197 ENSG00000270210.1 NA novel transcript lncRNA
ENSG00000198576 2.977386 3.720004 1.4817721 2.510510 0.0120557 0.0389991 ENSG00000198576.4 Q7LC44 ARC ARC 23237 activity regulated cytoskeleton associated protein [Source:HGNC Symbol;Acc:HGNC:648] protein_coding
ENSG00000166408 6.529267 1.885933 0.7528703 2.504991 0.0122454 0.0395248 ENSG00000166408.4 OR5P1P NA olfactory receptor family 5 subfamily P member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:14779] unprocessed_pseudogene
ENSG00000259644 9.397913 1.423072 0.5696966 2.497947 0.0124915 0.0402230 ENSG00000259644.1 NA novel transcript lncRNA
ENSG00000261544 10.865922 1.571144 0.6298273 2.494564 0.0126112 0.0405636 ENSG00000261544.1 NA novel transcript, intronic to DENND4A lncRNA
ENSG00000273812 12.284282 1.267592 0.5088169 2.491254 0.0127293 0.0408593 ENSG00000273812.3 LINC02970 NA long intergenic non-protein coding RNA 2970 [Source:HGNC Symbol;Acc:HGNC:56010] lncRNA
ENSG00000092929 17.086398 1.142073 0.4586621 2.490009 0.0127740 0.0409833 ENSG00000092929.13 K7EQ37 UNC13D UNC13D 201294 unc-13 homolog D [Source:HGNC Symbol;Acc:HGNC:23147] protein_coding
ENSG00000130558 16.487359 1.135372 0.4577781 2.480181 0.0131316 0.0419781 ENSG00000130558.20 Q99784 OLFM1 OLFM1 10439 olfactomedin 1 [Source:HGNC Symbol;Acc:HGNC:17187] protein_coding
ENSG00000287551 4.264919 2.654601 1.0711356 2.478305 0.0132008 0.0421729 ENSG00000287551.1 NA novel transcript, antisense to LINGO2 lncRNA
ENSG00000272574 13.137581 1.385684 0.5617132 2.466890 0.0136292 0.0433642 ENSG00000272574.1 NA novel transcript, sense intronic to UAP1 lncRNA
ENSG00000279970 2.835910 3.155782 1.2852747 2.455336 0.0140753 0.0446296 ENSG00000279970.1 NA TEC TEC
ENSG00000253983 5.633054 1.738105 0.7083747 2.453652 0.0141414 0.0448042 ENSG00000253983.3 NA novel transcript lncRNA
ENSG00000087128 15.694356 1.254325 0.5115853 2.451840 0.0142128 0.0450094 ENSG00000087128.10 A0A0G2JNI0 TMPRSS11E TMPRSS11E 28983 transmembrane serine protease 11E [Source:HGNC Symbol;Acc:HGNC:24465] protein_coding
ENSG00000124391 10.292329 1.425607 0.5819644 2.449647 0.0142996 0.0451928 ENSG00000124391.5 Q9P0M4 IL17C IL17C 27189 interleukin 17C [Source:HGNC Symbol;Acc:HGNC:5983] protein_coding
ENSG00000164849 15.251087 1.189436 0.4869462 2.442643 0.0145801 0.0459703 ENSG00000164849.10 C9J5X5 GPR146 GPR146 115330 G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718] protein_coding
ENSG00000021852 3.281312 3.130284 1.2850902 2.435847 0.0148569 0.0466998 ENSG00000021852.14 A0A8Q3SI88 C8B C8B 732 complement C8 beta chain [Source:HGNC Symbol;Acc:HGNC:1353] protein_coding
ENSG00000160867 9.201274 1.588446 0.6555653 2.423017 0.0153922 0.0481142 ENSG00000160867.15 P22455 FGFR4 FGFR4 2264 fibroblast growth factor receptor 4 [Source:HGNC Symbol;Acc:HGNC:3691] protein_coding
ENSG00000167748 18.190540 1.055093 0.4361664 2.419014 0.0155626 0.0485126 ENSG00000167748.11 P06870 KLK1 KLK1 3816 kallikrein 1 [Source:HGNC Symbol;Acc:HGNC:6357] protein_coding

GSEA analysis (logFc)

GOBP

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
GOBP_SISTER_CHROMATID_SEGREGATION 188 -0.5847771 -2.333110 0.0000000 0.0000000 0.0000000 1101 HECW2/PSRC1/FBXO5/ANAPC4/CCNB1/STAG3/TRIP13/CENPK/KIFC1/AXIN2/KIF4A/PTTG1/SPAG5/SGO2/TTK/DSCC1/CDT1/CDCA5/NDC80/KIF14/MAD2L1/CENPF/NCAPH/CENPE/NEK2/NUF2/PLK1/SGO1/KIF2C/BUB1/CEP55/ESCO2/CDC20/DLGAP5/KIF18B/NCAPG/UBE2C/TOP2A/BUB1B
GOBP_MITOTIC_SISTER_CHROMATID_SEGREGATION 162 -0.5888125 -2.300641 0.0000000 0.0000000 0.0000000 1101 HECW2/PSRC1/FBXO5/ANAPC4/CCNB1/TRIP13/CENPK/KIFC1/KIF4A/PTTG1/SPAG5/SGO2/TTK/DSCC1/CDT1/CDCA5/NDC80/KIF14/MAD2L1/CENPF/NCAPH/CENPE/NEK2/NUF2/PLK1/SGO1/KIF2C/BUB1/CEP55/CDC20/DLGAP5/KIF18B/NCAPG/UBE2C/BUB1B
GOBP_CHROMOSOME_SEGREGATION 308 -0.5391442 -2.273317 0.0000000 0.0000000 0.0000000 1256 KIF18A/ZCWPW1/M1AP/ABRAXAS1/PSMC3IP/HECW2/BRIP1/SPC24/PSRC1/FBXO5/FMN2/ANAPC4/CCNB1/STAG3/TRIP13/CENPK/KIFC1/AXIN2/KIF4A/PTTG1/SPAG5/KNL1/SKA3/SGO2/TTK/DSCC1/CDT1/CDCA5/NDC80/KIF14/MAD2L1/CENPF/CENPW/NCAPH/CDCA2/CENPE/NEK2/NUF2/CCNE2/PLK1/SGO1/SKA1/KIF2C/BUB1/CEP55/ESCO2/DMC1/CDC20/DLGAP5/KIF18B/OIP5/NCAPG/UBE2C/TOP2A/HJURP/BUB1B/SPC25/MKI67
GOBP_NUCLEAR_CHROMOSOME_SEGREGATION 250 -0.5396545 -2.230148 0.0000000 0.0000000 0.0000000 1256 KIF18A/ZCWPW1/M1AP/ABRAXAS1/PSMC3IP/HECW2/BRIP1/SPC24/PSRC1/FBXO5/FMN2/ANAPC4/CCNB1/STAG3/TRIP13/CENPK/KIFC1/AXIN2/KIF4A/PTTG1/SPAG5/KNL1/SGO2/TTK/DSCC1/CDT1/CDCA5/NDC80/KIF14/MAD2L1/CENPF/NCAPH/CENPE/NEK2/NUF2/CCNE2/PLK1/SGO1/KIF2C/BUB1/CEP55/ESCO2/DMC1/CDC20/DLGAP5/KIF18B/NCAPG/UBE2C/TOP2A/BUB1B/SPC25
GOBP_PROTEIN_DNA_COMPLEX_ASSEMBLY 165 -0.5624912 -2.223801 0.0000000 0.0000000 0.0000000 2253 NASP/MIS18A/H2BC9/HNF1B/NAP1L1/CENPH/H3C11/CENPS/H3C1/H2BC11/H3C13/H2BC15/H4C4/CHAF1B/H4C1/H3C10/HMGB2/H2BC7/H2BC3/HELLS/NAP1L3/H4C13/HEY2/CENPK/H4C9/CENPP/H2BC13/H1-5/CDT1/GMNN/H2BC14/H2BC10/CENPF/H3C7/CENPW/H1-1/ASF1B/H2BC17/H3C12/CENPE/DMC1/H3C3/DLGAP5/OIP5/HJURP/H3C8/H3C2
GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 265 0.5556219 2.187474 0.0000000 0.0000000 0.0000000 2607 SH2D1B/FGL2/EMILIN2/SOCS1/RASGRP1/ZBP1/SERPINB4/CD274/NCF1/TLR4/PTPN22/KLK7/ISG15/CD55/ADAM8/PPARG/OAS3/NOD2/OASL/GBP5/IL4I1/NLRC5/OAS1/PVR/RAET1G/CD36/IFIT1/EREG/IFI35/AIM2/SERPINB9/DDX60/USP18/LRP8/IRF7/TYRO3/ARRB2/APOE/UFD1/PARP9/MICA/RAET1E/NECTIN2/HCK/LY96/IFNLR1/DTX3L/TRIB1/CEACAM1/DUSP10/IL23A/ZC3H12A/AHR/CX3CL1/SYT11/ARG2/APPL2/PARP14/OPTN/CCL5/LGALS9/FYN/NLRP10/CARD9/RNF125/HERC5/SPINK5/ADAR/FADD/CXCL6/STAT1/MICB/PLSCR1/TRIM21/N4BP1/RIPK2/NPLOC4/TNFAIP3/AKIRIN2/SEC14L1/ZNFX1/IL15/BMP6/TRAFD1/HLA-F/STAT2/POLR3D/TRIM5/CGAS/SRC/PTPN11/MUL1/NOD1/BIRC3/TIGAR/PAK2
GOBP_MITOTIC_NUCLEAR_DIVISION 274 -0.5213324 -2.164997 0.0000000 0.0000000 0.0000000 1344 MTBP/INSR/KIF18A/PKMYT1/ABRAXAS1/HECW2/KIF11/CCDC8/PSRC1/FBXO5/ANAPC4/CCNB1/TRIP13/CENPK/KIFC1/EPGN/KIF4A/PTTG1/CDC14A/SPAG5/KIF20B/SGO2/TTK/DSCC1/CDT1/CDCA5/NDC80/KIF14/FBXO43/MAD2L1/CENPF/TPX2/NCAPH/CDCA2/CENPE/NEK2/NUF2/PLK1/SGO1/ANLN/KIF15/KIF2C/BUB1/CEP55/CDC20/DLGAP5/KIF18B/NCAPG/CDC25C/UBE2C/BUB1B/MYBL2/MKI67
GOBP_RESPONSE_TO_VIRUS 312 0.5070443 2.044662 0.0000000 0.0000000 0.0000000 2898 FGL2/ZBP1/APOBEC3A/HYAL1/PTPN22/CXCL10/CCL4/BATF3/IFIT2/MX2/RSAD2/ISG15/OAS3/CXCL9/ISG20/DUOX2/OASL/IFIT3/IFI44L/NLRC5/OAS1/VWCE/CCL22/MX1/MAP3K14/IFIT1/AIM2/BCL2/IFITM1/IFIH1/UNC13D/DDX60/IFI6/IRF7/GATA3/BST2/HYAL3/UFD1/TICAM1/PMAIP1/PARP9/MICA/IFI27/IFNLR1/DTX3L/OAS2/RIPK3/HIF1A/PML/FOSL1/IFITM3/ITGB8/IL23A/MYD88/TNF/ZC3H12A/SHFL/IFIT5/MAPK11/CCL5/LGALS9/CARD9/RNF125/HERC5/SERINC5/MST1R/ADAR/FADD/MLKL/STAT1/MICB/PLSCR1/TRIM21/EIF2AK2/ACTA2/APOBEC3B/TRIM25/NPLOC4/TNFAIP3/SEC14L1/ZNFX1/IL15/ITGB6/IFI44/ENO1/SAP30BP/RTP4/GBP1/FCN3/STAT2/POLR3D/AUP1/RELA/TRIM5/CGAS/SRC/MUL1/BIRC3/BCL3/CLPB/PDE12/CFL1/IFI16/MARCHF2/SMPD1/TRAF3IP2/NPC2/IKBKG/IL17RA/IKBKE
GOBP_ORGANELLE_FISSION 425 -0.4667736 -2.025623 0.0000000 0.0000000 0.0000000 1395 PEX11G/SHOC1/MTBP/INSR/KIF18A/RAD54B/ZCWPW1/HSPA2/PKMYT1/M1AP/ABRAXAS1/WNT5A/PSMC3IP/HECW2/KIF11/CCDC8/RAD54L/BRIP1/PSRC1/FBXO5/MEI1/FMN2/ANAPC4/CCNB1/PIWIL2/STAG3/HSF2BP/TRIP13/CENPK/KIFC1/EPGN/KIF4A/PTTG1/RAD51AP1/CDC14A/SPAG5/KIF20B/MYBL1/SGO2/MTFR2/TTK/DSCC1/CDT1/CDCA5/NDC80/KIF14/FBXO43/MAD2L1/CENPF/TPX2/CCNB2/NCAPH/CDCA2/CENPE/NEK2/NUF2/CCNE2/PLK1/SGO1/ANLN/CYP26B1/KIF15/KIF2C/BUB1/CEP55/DMC1/CDC20/DLGAP5/KIF18B/NCAPG/CDC25C/UBE2C/ASPM/TOP2A/CNTD1/BUB1B/MYBL2/MKI67
GOBP_REGULATION_OF_DEFENSE_RESPONSE 445 0.4800523 1.990991 0.0000000 0.0000000 0.0000000 2753 SH2D1B/FGL2/PLA2G3/CCN4/EMILIN2/SOCS1/TNFAIP6/RASGRP1/ZBP1/SERPINB4/ALOX15/NCF1/TLR4/PTPN22/IL1RL1/CNR1/KLK7/CTSC/ISG15/ADAM8/PPARG/OAS3/NOD2/KLF4/GBP5/LDLR/DUOXA1/ACE/NLRC5/FNDC4/OAS1/PVR/RAET1G/IFIT1/EREG/IFI35/AIM2/IDO1/SERPINB9/GPS2/DUOXA2/USP18/CD47/LRP8/IRF7/GATA3/TYRO3/PLA2G7/ARRB2/APOE/UFD1/PARP9/MICA/ANXA1/MVK/RAET1E/NECTIN2/HCK/CD200R1/OSMR/IFNLR1/DTX3L/MFHAS1/NFKBIA/METRNL/CEACAM1/DUSP10/PTGS2/IL23A/ZFP36/MYD88/SEMA7A/TNF/ZC3H12A/PSMA6/SOCS3/CX3CL1/SYT11/CALCRL/SPHK1/ARG2/TNIP1/APPL2/PARP14/OPTN/CCL5/LGALS9/FYN/NLRP10/CCN3/CARD9/RNF125/HERC5/SPINK5/SNCA/ADAR/FADD/IL1RL2/CXCL6/STAT1/MICB/PLSCR1/TRIM21/N4BP1/RIPK2/IL20RB/NPLOC4/TNFAIP3/AKIRIN2/SEC14L1/ZNFX1/IL15/CELF1/TRAFD1/FURIN/SBNO2/C2CD4B/TMSB4X/HLA-F/RORA/TRPV4/SELENOS/STAT2/GPER1/POLR3D/RELA/TRIM5/CYLD/CGAS/SRC/PTPN11/MUL1/RHBDF2/NOD1/BIRC3/NEAT1/PAK2/PPARD/IL6ST/BCR/MAPK13/ALOX5/RHBDD3/SYK/IFI16/SLC15A4/ABCC1
GOBP_CILIUM_ORGANIZATION 375 -0.4582800 -1.984009 0.0000000 0.0000000 0.0000000 4025 SPEF1/CFAP100/DNAAF11/CFAP157/LRGUK/TTC39C/CFAP298/RTTN/TBC1D8/TAPT1/TBC1D2B/UNC119B/ARL6/CEP41/TCTN1/IFT20/CEP250/DRC1/CEP164/ZMYND10/IQCB1/KIF3A/ARL13B/DYNLT2B/DNAI3/ARMC9/CFAP20/IFT46/TTC29/TMEM107/RAB17/ROPN1B/BBS10/CIBAR1/CEP135/SPATA6/ENO4/CCDC113/ODAD4/VDAC3/TEKT3/TOGARAM1/DNAAF2/ARL3/CEP19/WDPCP/TEKT5/RSPH4A/TBC1D15/DYNC2I1/PIBF1/DNAJB13/CFAP126/BBS9/CLUAP1/NEK1/CCDC66/CCDC39/CFAP54/TMEM216/DNAI1/BBIP1/IFT122/IFT43/TCTN2/CFAP74/SPAG17/DNAAF10/HYDIN/WDR90/BBS2/DNAL1/NOTCH1/BBOF1/WDR19/CENPJ/TBC1D32/ARMC2/CBY1/CFAP52/DCDC2/KIF24/DYNC2LI1/TMEM67/MAPK15/KIF27/B9D1/PCM1/CEP83/RPGR/FOXJ1/CEP97/CCDC96/CCP110/DNAAF3/POC1A/SPEF2/CEP120/CCDC65/TUB/CATIP/TTC21A/PKHD1/RSPH9/DNAH7/CFAP58/FAM161A/IFT57/IFT140/CEP162/TEKT2/CFAP61/CFAP69/IFT27/CFAP91/ODF2L/CC2D2A/UBXN10/LCA5/DRC7/IFT88/SPAG16/TMEM237/IFT52/FUZ/CFAP47/IFT74/TTC12/RFX2/CILK1/BBS12/DNAH1/IFT81/ODAD3/RPGRIP1L/WDR35/IQCG/CIBAR2/IFT172/NME5/RSPH1/CPLANE2/CFAP73/IFT80/TMEM138/DYNC2H1/DAW1/CFAP221/MKS1/B9D2/CFAP44/RFX3/CFAP65/CEP78/DNAI4/KIF19/DNAAF1/DNAAF4/CEP70/TEKT1/DNAI2/DZIP1L/BBS4/IQUB/MNS1/HOATZ/CFAP70/CFAP43/LCA5L/LRRC49/MPHOSPH9/CFAP206/TEKT4/CDKL1/CFAP161/CCDC13/DNAH2/TTC21B/DNAH5/CROCC/RP1/DNAAF6/DNAAF8/CFAP53/ODAD2/HYLS1/MEIG1/ABCC4/SAXO1/NEURL1/CDC14A/MCIDAS/CCNO/PLK4/GMNC
GOBP_CYTOKINE_MEDIATED_SIGNALING_PATHWAY 339 0.4915632 1.986268 0.0000000 0.0000001 0.0000001 2580 CCL26/SOCS1/ZBP1/IL1R2/IL13RA2/IL1RL1/CXCL10/CCL4/ISG15/CXCL11/CD44/PPARG/IL12RB2/OAS3/IL36G/CXCL9/DUOX2/OASL/IL17REL/NLRC5/OAS1/SLIT2/CXCL8/CCL22/MX1/IL2RG/EREG/IL31RA/AIM2/EBI3/F3/IL36A/IFITM1/IL1A/GPS2/USP18/EGR1/CLCF1/LRP8/CD70/IRF7/DUOX1/DOK1/EDN1/PARP9/IL1RN/IFI27/CCR3/HCK/OSMR/ACSL1/PXDN/IFNLR1/OAS2/IL18R1/IRAK2/NFKBIA/HIF1A/IFITM3/CEACAM1/CXCL1/MYD88/TNF/PLP2/LIFR/FAS/KRT18/IL1RAPL2/CX3CL1/YAP1/SPHK1/RPS6KA4/IL4R/APPL2/PARP14/CCL5/TNFRSF19/CXCL2/IL15RA/TNFRSF25/AXL/SH2B3/MST1R/ADAR/OXSR1/FADD/IL1RL2/CXCL6/STAT1/IRAK1/RIPK2/IL20RB/TRAF5/CDIP1/TNFAIP3/TNFRSF13C/IL15/CSNK2B/ST18/ADIPOR2/AKT1/TMSB4X/ADAM17/IRAK4/STAT2/PF4V1/GAS6/RELA/GFI1/RFFL/CYLD/SRC/PTPN11/CCL20/MUL1/IL27RA/BIRC3/WBP1L/CSF2
GOBP_NUCLEOSOME_ASSEMBLY 94 -0.6254620 -2.249064 0.0000000 0.0000007 0.0000005 2253 NASP/MIS18A/H2BC9/NAP1L1/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/CHAF1B/H4C1/H3C10/HMGB2/H2BC7/H2BC3/NAP1L3/H4C13/H4C9/CENPP/H2BC13/H1-5/H2BC14/H2BC10/H3C7/CENPW/H1-1/ASF1B/H2BC17/H3C12/H3C3/OIP5/HJURP/H3C8/H3C2
GOBP_DNA_PACKAGING 206 -0.5065113 -2.045426 0.0000000 0.0000007 0.0000006 2332 SMC4/HDAC5/NASP/MIS18A/H2BC9/NAP1L1/SMC2/H3C11/H3C1/H2BC11/H3C13/H2BC15/TET1/H4C4/CHAF1B/H4C1/M1AP/H3C10/HMGB2/H2BC7/H2BC3/HELLS/NAP1L3/H4C13/H4C9/ATF7IP2/CENPP/H2BC13/H1-5/CDCA5/H2BC14/H2BC10/H3C7/CENPW/H1-1/NCAPH/ASF1B/H2BC17/H3C12/PLK1/CDK1/H3C3/OIP5/NCAPG/TOP2A/HJURP/H3C8/H3C2
GOBP_STEROL_BIOSYNTHETIC_PROCESS 53 0.7521629 2.332720 0.0000000 0.0000008 0.0000007 887 CYP51A1/MVD/HMGCS1/EBP/FDPS/LSS/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/FDFT1/SQLE/NSDHL/ACLY/SC5D/G6PD/APOE/TM7SF2/ERG28/MVK
GOBP_REGULATION_OF_CHROMOSOME_SEGREGATION 81 -0.6473587 -2.282139 0.0000000 0.0000015 0.0000012 1101 HECW2/FBXO5/ANAPC4/CCNB1/TRIP13/PTTG1/TTK/CDT1/NDC80/MAD2L1/CENPF/CDCA2/CENPE/PLK1/KIF2C/BUB1/DLGAP5/UBE2C/BUB1B/MKI67
GOBP_DNA_CONFORMATION_CHANGE 300 -0.4545535 -1.912151 0.0000000 0.0000018 0.0000015 2521 H4C3/HMGB1/H4C2/RFC5/MRE11/SMC4/HDAC5/NASP/MIS18A/H2BC9/ZRANB3/CHTF8/NAP1L1/SMC2/H3C11/H3C1/DNA2/H2BC11/H3C13/H2BC15/TET1/H4C4/CHAF1B/H4C1/MCM8/RAD54B/M1AP/BLM/GINS1/GINS2/RAD54L/BRIP1/H3C10/HMGB2/H2BC7/H2BC3/HELLS/RECQL4/POLQ/NAP1L3/H4C13/H4C9/MCMDC2/CHD1L/ATF7IP2/CENPP/H2BC13/H1-5/DSCC1/CDCA5/H2BC14/H2BC10/H3C7/CENPW/H1-1/NCAPH/ASF1B/H2BC17/H3C12/PLK1/CDK1/ERCC6L/H3C3/OIP5/NCAPG/TOP2A/HJURP/H3C8/H3C2
GOBP_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION 211 -0.4908236 -1.988399 0.0000000 0.0000025 0.0000020 3971 NPM1/H2BC12/PIH1D1/TSPYL4/ITGB3BP/RUVBL1/ACTL6A/H3-3A/H1-3/CENPC/H2AX/KNTC1/H3C6/MCM2/H2BC6/H4C5/ACTR6/GTF2H5/NAP1L4/SMARCE1/H2BC5/H4C12/RUVBL2/RPL23/RAD52/SMYD3/TCF4/ANP32E/H4C6/H2BC4/ESR1/H4C3/HMGB1/H4C2/NASP/MIS18A/H2BC9/HNF1B/NAP1L1/CENPH/H3C11/CENPS/H3C1/H2BC11/H3C13/H2BC15/H4C4/CHAF1B/H4C1/H3C10/HMGB2/H2BC7/SMARCD3/H2BC3/HELLS/INO80B/NAP1L3/H4C13/HEY2/CENPK/H4C9/CENPP/H2BC13/H1-5/CDT1/GMNN/H2BC14/H2BC10/CENPF/H3C7/CENPW/H1-1/ASF1B/H2BC17/H3C12/CENPE/DMC1/H3C3/DLGAP5/OIP5/HJURP/H3C8/H3C2
GOBP_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS 476 0.4279468 1.789366 0.0000000 0.0000033 0.0000028 2869 NOS2/CISH/SOCS1/PNPLA3/ALOX15/IDO2/MVD/HMGCS1/ADCY5/FDPS/ELOVL6/SLC5A8/ACSS2/NNMT/GARS1/IDI1/FADS1/HAAO/ME1/ADCY4/CMPK2/LPIN1/MFSD2A/HRH1/ELOVL5/PLA2G4C/ACLY/ABHD4/IDO1/SOCS2/ANTKMT/ADCY7/LCAT/LIPH/FGF2/GUCY2C/G6PD/SRD5A3/PARP9/ELOVL7/PLA2G4A/MVK/P2RY1/HSD17B12/ACSL1/QPRT/PANK3/SERAC1/TKT/GPAT3/LPCAT4/FAR1/IDH1/ACOT7/SLC25A1/SOCS3/GCH1/PTAFR/NAMPT/UCKL1/TPK1/ELOVL1/PISD/TMEM150A/SGMS1/PIGW/ACSL4/SERINC5/PTPMT1/SELENOI/P2RY6/NOS1/ELOVL4/SNCA/SAMD8/ACACA/PLSCR1/ITPKA/ADCY10/KYNU/UPP1/GPAT4/PGAP4/NADK/VPS9D1/PIP4K2A/DGKQ/PARP10/DHDDS/TAFAZZIN/PDXK/ACP6/CKMT1B/CKMT1A/FLCN/CAPN2/PIP5K1A/ENO1/ATP5MC1/INPP1/MBOAT1/PIK3C2B/PDHA1/PLD2/TMSB4X/MYC/INPPL1/DGKA/GPER1/PTDSS1/CHP1/ATP5F1D/CTPS1/PITPNM2/ITPKC/PPARD/DOLK/NAPRT/PPARGC1A/MOCOS/TTC7A/AKR1A1/ABHD3/ACSL3/HACD1/FLAD1/IPPK
GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 235 0.5078902 1.966624 0.0000000 0.0000044 0.0000036 1872 SH2D1B/NOS2/FGL2/PLA2G3/RASGRP1/IL13RA2/SERPINB4/NCF1/TLR4/PTPN22/KLK7/RSAD2/CD55/NOD2/IL4I1/PVR/RAET1G/CD36/SERPINB9/FZD5/UNC13D/DDX60/CLCF1/CD47/SLC7A5/GATA3/BST2/ARRB2/TNFSF13/TICAM1/CD86/MICA/ANXA1/RAET1E/NECTIN2/COLEC10/IL18R1/RIPK3/NFKBID/ARID5A/CEACAM1/DUSP10/IL23A/SEMA7A/ICAM1/TNF/ZC3H12A/AHR/GAB2/HK1/HMOX1/IL4R/PTAFR/TRPM4/APPL2/ZBTB7B/LGALS9/NR4A3/ITGAM/SPINK5/FADD/CXCL6/RIPK2/IL20RB
GOBP_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS 287 0.4769580 1.897587 0.0000000 0.0000044 0.0000036 2722 FGL2/DPP4/SOCS1/TNFAIP6/THY1/IL13RA2/SERPINB4/ALOX15/CD274/LGALS7B/TLR4/PTPN22/PDCD1LG2/IL1RL1/CNR1/SFRP1/ISG15/CD55/PPARG/OAS3/NOD2/LDLR/IL4I1/NLRC5/OAS1/SLIT2/IL31RA/IDO1/SERPINB9/GPS2/USP18/CD47/BST2/TYRO3/ARRB2/CD86/MICA/ANXA1/HCK/CD200R1/KITLG/HLA-DOB/TRIB1/SOX9/CEACAM1/DUSP10/TNF/ZC3H12A/AHR/DUSP3/CX3CL1/SYT11/HMOX1/ARG2/IL4R/DLG1/PARP14/ZBTB7B/LGALS9/THBS1/FYN/CCN3/GREM1/AXL/SPINK5/MMP28/ADAR/FADD/TRIM21/IL20RB/TNFAIP3/CD46/FCRLB/WASL/TRAFD1/FURIN/PRNP/DLG5/SCRIB/GBP1/PAWR/AKT1/HLA-F/MYC/SELENOS/UBASH3B/STAT2/GPER1/RUNX1/SRC/MUL1/RHBDF2/IL27RA/MIA3/BCR/LGALS3/RHBDD3/SYK/IFI16
GOBP_DEFENSE_RESPONSE_TO_SYMBIONT 234 0.5122573 1.981033 0.0000000 0.0000047 0.0000039 2730 FGL2/ZBP1/APOBEC3A/PTPN22/CXCL10/IFIT2/MX2/RSAD2/ISG15/OAS3/CXCL9/ISG20/OASL/IFIT3/IFI44L/NLRC5/OAS1/MX1/MAP3K14/IFIT1/AIM2/BCL2/IFITM1/IFIH1/UNC13D/DDX60/IFI6/IRF7/BST2/UFD1/TICAM1/PMAIP1/PARP9/MICA/IFI27/IFNLR1/DTX3L/OAS2/RIPK3/PML/IFITM3/IL23A/MYD88/ZC3H12A/SHFL/IFIT5/CARD9/RNF125/HERC5/SERINC5/ADAR/FADD/MLKL/STAT1/MICB/PLSCR1/TRIM21/EIF2AK2/APOBEC3B/TRIM25/NPLOC4/TNFAIP3/SEC14L1/ZNFX1/IL15/RTP4/GBP1/FCN3/STAT2/POLR3D/RELA/TRIM5/CGAS/MUL1/BIRC3/CLPB/PDE12/IFI16/MARCHF2
GOBP_MEIOTIC_CELL_CYCLE 198 -0.4775727 -1.918379 0.0000001 0.0000211 0.0000174 1416 XRCC2/MNS1/SHOC1/INSR/KIF18A/RAD54B/ZCWPW1/HSPA2/WBP2NL/PKMYT1/M1AP/WNT5A/PSMC3IP/CDC25A/RAD54L/BRIP1/FBXO5/MEI1/FMN2/PIWIL2/STAG3/HSF2BP/TRIP13/MCMDC2/PTTG1/RAD51AP1/EXO1/MYBL1/SGO2/TTK/NDC80/FBXO43/CCNB2/NCAPH/NEK2/NUF2/CCNE2/PLK1/SGO1/CYP26B1/BUB1/DMC1/CDC20/CDC25C/ASPM/TOP2A/CNTD1/BUB1B
GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS 302 0.4693532 1.879433 0.0000001 0.0000211 0.0000174 2753 CCL26/SH2D1B/PLA2G3/CCN4/EMILIN2/RASGRP1/ZBP1/TLR4/IL1RL1/CXCL10/PRKD1/CNR1/CCL4/KLK7/CTSC/ADAM8/NOD2/OASL/GBP5/LDLR/ACE/NLRC5/SLIT2/CXCL8/PVR/RAET1G/EREG/ARTN/NTRK3/IFI35/AIM2/F3/IDO1/VEGFA/DDX60/FGF2/DAPK2/CD47/IRF7/SMOC2/PLA2G7/EDN1/PARP9/MET/RAET1E/NECTIN2/HCK/LY96/OSMR/NFKBIA/STX3/S100A7/THBD/PTGS2/IL23A/KDR/TNF/CAMK1D/CX3CL1/TNIP1/OPTN/CCL5/LGALS9/THBS1/FYN/NLRP10/NDEL1/FKBP1B/CARD9/P2RX4/SNCA/OXSR1/FADD/RAC1/PLSCR1/RIPK2/SCG2/AKIRIN2/ZNFX1/IL15/BMP6/MCU/C2CD4B/TMSB4X/HLA-F/ADAM17/TRPV4/POLR3D/GAS6/TRIM5/STX4/CGAS/SRC/NOD1/NEAT1/PAK2/IL6ST/MAPK13/S100A14/SYK/IFI16/SLC15A4/ABCC1
GOBP_MICROTUBULE_BASED_MOVEMENT 330 -0.4188094 -1.784974 0.0000001 0.0000244 0.0000201 3518 DRC1/HSPB1/ZMYND10/KIF2A/KIF3A/DNAL4/CFAP251/DYNLT2B/DNAI3/CFAP20/IFT46/TTC29/ROPN1B/AGBL4/SLC22A16/ENO4/ODAD4/TEKT3/DNAAF2/ARL3/TEKT5/RSPH4A/DYNLT1/DYNC2I1/AP3M2/CCDC39/CFAP54/DNAI1/IFT122/KIF7/IFT43/SPAG17/HYDIN/BBS2/KIF23/WDR19/KIF6/ARMC2/CFAP52/KIF17/KIF24/DYNC2LI1/KIF27/MAPK8IP3/KATNIP/PCM1/ZBBX/RPGR/DPCD/SPEF2/CCDC65/TUB/TTC21A/RSPH9/GAS2L2/DNAH7/CFAP58/IFT57/ROPN1L/IFT140/TEKT2/CFAP61/CFAP69/IFT27/CFAP91/MAP1A/LCA5/DRC7/IFT88/INPP5B/MAPT/SPAG16/IFT52/CFAP47/SPA17/IFT74/TTC12/DNAH9/CILK1/BBS12/DNAH1/IFT81/ODAD3/WDR35/SLC26A8/IQCG/IFT172/NME5/CLN3/CFAP73/DYNC2H1/DAW1/CFAP221/CFAP44/DYNLT2/AQP4/RFX3/CFAP65/PLTP/NEFL/DNAH3/DNAI4/KIF19/DNAAF1/DNAAF4/TEKT1/KIF22/DNAI2/DNAH6/BBS4/MNS1/HOATZ/CFAP70/TCTE1/CFAP43/DNAH10/LCA5L/CFAP45/KIF18A/CFAP206/TEKT4/KIF26B/STARD9/KIF11/DYNLRB2/DNAH2/TTC21B/TTLL6/DNAH5/FMN2/DNAAF6/CFAP53/ODAD2/CNIH2/KIFC1/NEK10/KIF21A/MEIG1/DLG2/KIF4A/NEURL1/KIF20B/KIF14/DYNLT4/CENPE/CATSPERD/KIF15/KIF2C/EPPIN/KIF20A/DLGAP5/KIF18B
GOBP_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS 437 0.4208893 1.748098 0.0000002 0.0000291 0.0000239 2372 PLA2G3/APOC1/ALOX15/CBS/CYP51A1/MVD/HMGCS1/EBP/TRIB3/TBXAS1/FADS2/PSAT1/FDPS/ELOVL6/LSS/LIPG/DHCR7/MSMO1/HMGCR/INSIG1/PCK2/NNMT/HSD17B7/IDI1/FGFR4/FADS1/STARD4/ALDH1A3/ASNS/HAAO/FDFT1/HRH1/ELOVL5/BCAT1/ALOXE3/SCD/NSDHL/PYCR1/FA2H/ACLY/PHGDH/IDO1/SC5D/ALOX15B/LIPH/SESN2/FGF2/EGR1/FASN/G6PD/MTHFD1L/SRD5A3/APOE/DPYD/TM7SF2/EDN1/FBP1/ELOVL7/PLA2G4A/GOT1/ATF4/CTH/CYP27B1/ANXA1/MVK/P2RY1/PRTFDC1/HSD17B12/SHMT2/GGT5/ERFE/CEACAM1/PTGS2/MLXIPL/TNF/AMD1/ACOT7/SLC25A1/CYP46A1/SPHK1/GCH1/PTAFR/GGT7/BMP2/LTA4H/HSD3B7/UCKL1/TPK1/ELOVL1/CYP2C9/PPTC7/SERINC5/ACADL/P2RY6/ELOVL4/SNCA/ACACA/PLOD3/NAGS/AACS/ITPKA/FAM3C/KYNU/NLN/DGKQ/ATF3/DHDDS/PDXK/ASS1/SLC39A14/PGD/BMP6/SLC35B4/ACER2/DHCR24/MID1IP1/KAT2B/GLS/SELENOS/ASAH2/CYB5R3/GPER1
GOBP_IMMUNE_EFFECTOR_PROCESS 393 0.4324209 1.770190 0.0000002 0.0000319 0.0000262 2641 SH2D1B/NOS2/FGL2/PLA2G3/RASGRP1/IL13RA2/C8B/SERPINB4/NCF1/TLR4/PTPN22/TCIM/KLK7/CTSC/RSAD2/CD55/LAT2/NOD2/ACE/IL4I1/ULBP1/PVR/RAET1G/CD36/IFI35/SERPINB9/FZD5/UNC13D/DDX60/CLCF1/CD47/SLC7A5/CD70/IRF7/GATA3/BST2/ANXA3/ARRB2/TNFSF13/TICAM1/CD86/MICA/RELB/ANXA1/RAET1E/NECTIN2/COLEC10/ULBP2/HCK/DOCK11/HLA-DOB/IL18R1/RIPK3/NFKBID/ARID5A/CEACAM1/DUSP10/IL23A/MYD88/SEMA7A/ICAM1/TNF/CEBPG/ZC3H12A/CFB/AHR/GAB2/HK1/HMOX1/IL4R/PTAFR/TRPM4/APPL2/ZBTB7B/LGALS9/FYN/NR4A3/ITGAM/CARD9/RNF19B/TUBB/SPINK5/FADD/CXCL6/ULBP3/RIPK2/IL20RB/C1S/RNF8/CD46/SHLD2/WDR1/BATF/SBNO2/BCL10/LIMK1/HLA-DQB2/PLD2/HLA-F/ADAM17/RORA/IRAK4/FCN3/C2/CD177/PLEC/STX4/CGAS/SRC/IL27RA/BCL3/STXBP2/BCR/LGALS3
GOBP_SISTER_CHROMATID_COHESION 54 -0.6726041 -2.199664 0.0000002 0.0000381 0.0000313 2514 PDS5B/HORMAD1/HASPIN/MRE11/CHTF8/ESPL1/KIF22/STAG3/AXIN2/SGO2/DSCC1/CDCA5/PLK1/SGO1/BUB1/ESCO2/CDC20/BUB1B
GOBP_RESPONSE_TO_INTERFERON_GAMMA 104 0.6072704 2.122520 0.0000003 0.0000381 0.0000313 2702 CCL26/NOS2/SOCS1/TLR4/CCL4/PPARG/GBP5/NLRC5/CCL22/UBD/CXCL16/IFITM1/CD47/BST2/EDN1/PARP9/CYP27B1/HCK/SLC26A6/IFITM3/TNF/MYO1C/CX3CL1/SHFL/GCH1/PARP14/CCL5/LGALS9/EPRS1/GSN/SNCA/RAB43/STAT1/TRIM21/KYNU/ASS1/DAPK3/GBP1/MYC/STX4/CCL20/GBP4/CLDN1/CALCOCO2/PDE12/ACTG1
GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE 170 0.5393717 2.001428 0.0000002 0.0000381 0.0000313 2740 SH2D1B/SOCS1/RASGRP1/ZBP1/SERPINB4/NCF1/TLR4/PTPN22/ISG15/ADAM8/PPARG/OAS3/NOD2/GBP5/NLRC5/OAS1/PVR/RAET1G/EREG/IFI35/AIM2/SERPINB9/USP18/LRP8/IRF7/TYRO3/ARRB2/APOE/PARP9/MICA/RAET1E/NECTIN2/HCK/CEACAM1/DUSP10/APPL2/PARP14/CCL5/LGALS9/FYN/CARD9/ADAR/FADD/PLSCR1/TRIM21/N4BP1/TNFAIP3/AKIRIN2/ZNFX1/TRAFD1/HLA-F/STAT2/POLR3D/TRIM5/CGAS/SRC/PTPN11/MUL1/BIRC3/PAK2/SYK/IFI16/SLC15A4
GOBP_NUCLEOSOME_ORGANIZATION 139 -0.5187049 -1.984320 0.0000003 0.0000381 0.0000313 3971 NPM1/H2BC12/TSPYL4/ITGB3BP/RUVBL1/ACTL6A/H3-3A/H1-3/H2AX/H3C6/MCM2/H2BC6/H4C5/ACTR6/NAP1L4/SMARCE1/H2BC5/H4C12/RUVBL2/SMYD3/ANP32E/H4C6/H2BC4/H4C3/H4C2/NASP/MIS18A/H2BC9/NAP1L1/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/CHAF1B/H4C1/H3C10/HMGB2/H2BC7/SMARCD3/H2BC3/INO80B/NAP1L3/H4C13/H4C9/CENPP/H2BC13/H1-5/H2BC14/H2BC10/H3C7/CENPW/H1-1/ASF1B/H2BC17/H3C12/H3C3/OIP5/HJURP/H3C8/H3C2
GOBP_CELLULAR_RESPONSE_TO_PEPTIDE 286 0.4642742 1.849026 0.0000003 0.0000381 0.0000313 1639 NTRK1/ANO1/SOCS1/CA2/PNPLA3/EDNRA/TLR4/PTPN22/TRIB3/PCSK9/INSIG1/PCK2/GJB2/PPARG/MAP1B/KL/NOD2/LPIN1/NR4A1/CPEB2/PRKCQ/CD36/MIR200A/GDF15/HDAC9/KLF11/MARS1/SOCS2/KLF2/SLC29A2/CACNB1/EDN1/FBP1/GOT1/PTPRE/GRB10/ENPP1/ERFE/RAB8B/CEACAM1/ICAM1/TNF/SLC27A4/MYO1C/SOCS3/IRS2/CAV2/RAB31/NAMPT/APPL2/ZBTB7B/GRB14/EPRS1/BCAR1/FYN/ERRFI1/CCND3/NDEL1/NR4A3/RAB15/SLC9A1
GOBP_LEUKOCYTE_DIFFERENTIATION 404 0.4213027 1.732894 0.0000004 0.0000606 0.0000498 2403 NTRK1/FGL2/PLA2G3/CCN4/SOCS1/TNFAIP6/RASGRP1/TLR4/PTPN22/FZD9/SLC9B2/BATF3/PRDM1/SFRP1/MT1G/RSAD2/ADAM8/PPARGC1B/PPARG/BATF2/RUNX2/BCL11B/IL4I1/KLF6/DLL4/IL31RA/UBD/HDAC9/FOS/HHEX/BCL2/VEGFA/IL1A/FZD5/TOX/GPS2/EGR1/CLCF1/FASN/LRRC8A/IRF7/GATA3/TYRO3/CD86/RELB/ANXA1/KITLG/DOCK11/TNFSF9/IL18R1/RIPK3/TRIB1/NFKBID/BAK1/IKZF1/CARD11/ROR2/CEACAM1/DUSP10/ITGB8/IL23A/TNF/NFIL3/CEBPG/ZC3H12A/GAB2/CD83/LIF/IL4R/CMTM7/EPHA2/ZBTB7B/LGALS9/TFE3/IL15RA/AXL/SPINK5/FADD/IL1RL2/PRXL2A/MYH9/RIPK2/PRELID1/FAM20C/JUNB/CD46/IL15/BATF/ITGB6/SBNO2/LTBR/PIR/AP3D1/JUN/ADAM17/RORA/MYC/UBASH3B/GAS6/JMJD6
GOBP_RESPONSE_TO_WOUNDING 433 0.4210333 1.746689 0.0000004 0.0000615 0.0000505 2729 NTRK1/CCN4/ADRA2C/EMILIN2/C1QTNF1/VWF/SELP/EDNRA/ALOX15/SERPINB2/SPRR3/TLR4/PROCR/RTN4R/HBEGF/SLC7A11/SERPINC1/PLAUR/CD44/PHLDB2/PPARG/FAP/MAP1B/KLF4/PAX6/DUOX2/PRKCQ/CD36/EREG/NTRK3/TNC/F3/BCL2/VEGFA/IL1A/PLAU/SLC12A2/FGF2/CLASP1/GRHL3/SMOC2/DUOX1/TYRO3/APOE/EDN1/TNFRSF12A/PLA2G4A/CD9/ANXA1/P2RY1/KRT6A/EPPK1/SCARB1/NOTCH4/MSX2/THBD/HIF1A/VCL/PEAR1/OCLN/TFPI2/ANXA8/CEACAM1/ZFP36/KDR/TNF/CDH3/CLDN4/CX3CL1/SYT11/HMOX1/RIPOR1/YAP1/ID3/NREP/ST3GAL4/THBS1/SOX2/NDEL1/FKBP1B/LOX/AXL/SH2B3/RAP2B/ENTPD2/P2RX4/MYOF/RAC1/PLSCR1/ACTA2/TGFA/MYH9/DGKI/TEC/TNFAIP3/DGKQ/CHMP6/ACTB/CSRP1/TIMP1/ITGB6/ADIPOR2/CDKN1A/SCRIB/SPP1/CHMP7/GNA12/ITPK1/RHOC/JUN/TGFBR1/ADAM17/MYC/DGKA/UBASH3B/PF4V1/GAS6/TMPRSS4/CD151/PDPN/PLEC/ACTN1/SRC/CLDN1/FERMT1/PPARD/CADM4/IL6ST/MIA3/MAP2K1/ALOX5/ACTG1/SYK/DAG1/PAFAH2
GOBP_WOUND_HEALING 337 0.4423733 1.784336 0.0000005 0.0000656 0.0000539 3002 CCN4/ADRA2C/EMILIN2/C1QTNF1/VWF/SELP/ALOX15/SERPINB2/SPRR3/TLR4/PROCR/HBEGF/SLC7A11/SERPINC1/PLAUR/CD44/PHLDB2/PPARG/FAP/DUOX2/PRKCQ/CD36/EREG/F3/VEGFA/IL1A/PLAU/SLC12A2/FGF2/CLASP1/GRHL3/SMOC2/DUOX1/TYRO3/APOE/EDN1/TNFRSF12A/PLA2G4A/CD9/ANXA1/P2RY1/KRT6A/EPPK1/SCARB1/NOTCH4/MSX2/THBD/HIF1A/VCL/PEAR1/OCLN/TFPI2/ANXA8/CEACAM1/KDR/TNF/CDH3/CLDN4/CX3CL1/SYT11/HMOX1/YAP1/ST3GAL4/THBS1/LOX/AXL/SH2B3/RAP2B/ENTPD2/MYOF/PLSCR1/ACTA2/TGFA/MYH9/DGKI/TEC/TNFAIP3/DGKQ/CHMP6/ACTB/CSRP1/TIMP1/ITGB6/ADIPOR2/CDKN1A/SCRIB/CHMP7/GNA12/ITPK1/RHOC/TGFBR1/ADAM17/DGKA/UBASH3B/PF4V1/GAS6/CD151/PDPN/PLEC/ACTN1/SRC/CLDN1/FERMT1/PPARD/CADM4/IL6ST/MIA3/ALOX5/ACTG1/SYK/DAG1/PAFAH2/VAV2/SMPD1/CAV1/DGKD/MYL12A/CRK/FERMT2/COMP/GGCX
GOBP_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE 61 -0.6410830 -2.127126 0.0000006 0.0000795 0.0000653 1101 HECW2/FBXO5/ANAPC4/CCNB1/TRIP13/TTK/CDT1/NDC80/MAD2L1/CENPF/CENPE/PLK1/BUB1/DLGAP5/UBE2C/BUB1B
GOBP_REGULATION_OF_CHROMOSOME_SEPARATION 66 -0.6289327 -2.116362 0.0000007 0.0000825 0.0000678 1101 HECW2/FBXO5/ANAPC4/CCNB1/TRIP13/PTTG1/TTK/CDT1/NDC80/MAD2L1/CENPF/CENPE/PLK1/BUB1/DLGAP5/UBE2C/BUB1B
GOBP_TAXIS 433 0.4172267 1.730897 0.0000007 0.0000857 0.0000704 1885 CCL26/NTRK1/DPP4/GDNF/TNFAIP6/LGR6/EDNRA/DLX5/PTPRO/DEFB4A/CXCL10/PRKD1/HBEGF/CCL4/BDNF/SEMA3B/PLAUR/CH25H/CXCL11/ADAM8/CRMP1/NOD2/CXCL9/PAX6/ARHGEF5/BCL11B/FOXD1/HRH1/NR4A1/SLIT2/CXCL8/CCL22/PRKCQ/FLT1/ST6GAL1/ARTN/NTRK3/AMOT/CXCL16/F3/VEGFA/PLAU/CMTM3/RELN/SLC12A2/FGF2/EPHB3/DAPK2/GATA3/SMOC2/PLA2G7/ARRB2/SEMA3D/TUBB3/EDN1/EGR2/MET/ANXA1/CCR3/COLEC10/ANOS1/EPHA3/STX3/S100A7/NRP2/FOSL1/PLXNA3/CXCL1/IL23A/KDR/SEMA7A/CAMK1D/PLP2/NRCAM/NIBAN2/DUSP3/CX3CL1/EPHA10/ITGA9/SEMA3A/SEMA4C/PTAFR/TRPM4/CMTM7/ECE1/EPHA2/PLEKHG5/CCL5/HSD3B7/LGALS9/SEMA6A/THBS1/BCAR1/FYN/RHOG/CXCL2/CCN3/SLIT1/GREM1/LOX/NTN1/DPYSL2/MMP28/P2RX4/IGSF9/ITGAV/OXSR1/PDE4B/CXCL6/RAC1/SLC8B1/TYMP/KIF5C/VASP
GOBP_REGULATION_OF_NUCLEAR_DIVISION 116 -0.5397231 -2.006606 0.0000009 0.0001046 0.0000859 1344 MTBP/INSR/PKMYT1/WNT5A/CCDC8/FBXO5/ANAPC4/CCNB1/PIWIL2/TRIP13/EPGN/RAD51AP1/KIF20B/TTK/CDT1/NDC80/FBXO43/MAD2L1/CENPF/CDCA2/NEK2/PLK1/BUB1/CDC20/DLGAP5/CDC25C/BUB1B/MKI67
GOBP_ALCOHOL_BIOSYNTHETIC_PROCESS 108 0.5903293 2.061729 0.0000010 0.0001109 0.0000911 2650 CYP51A1/MVD/HMGCS1/EBP/FDPS/LSS/DHCR7/MSMO1/HMGCR/INSIG1/PCK2/HSD17B7/IDI1/FDFT1/HRH1/NSDHL/ACLY/SC5D/FGF2/G6PD/SRD5A3/APOE/TM7SF2/GOT1/CYP27B1/MVK/P2RY1/SPHK1/GCH1/PTAFR/BMP2/P2RY6/SNCA/ITPKA/DGKQ/DHDDS/BMP6/ACER2/DHCR24/ASAH2/CYB5R3/GPER1/GFI1/ITPKC/SPTSSA/PTS
GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE 120 0.5749977 2.037943 0.0000010 0.0001109 0.0000911 2722 FGL2/IL13RA2/SERPINB4/ALOX15/IL1RL1/ISG15/CD55/PPARG/OAS3/NOD2/IL4I1/NLRC5/OAS1/SERPINB9/USP18/TYRO3/ARRB2/MICA/ANXA1/HCK/CEACAM1/DUSP10/ZC3H12A/AHR/HMOX1/ARG2/IL4R/PARP14/ZBTB7B/LGALS9/FYN/SPINK5/ADAR/TRIM21/IL20RB/TNFAIP3/CD46/FCRLB/TRAFD1/FURIN/HLA-F/SELENOS/STAT2/SRC/MUL1/RHBDF2/IL27RA/BCR/LGALS3/SYK/IFI16
GOBP_ANION_TRANSPORT 360 0.4261495 1.728338 0.0000010 0.0001109 0.0000911 2163 NOS2/ANO1/PLA2G3/GABRA4/SLC5A5/SLC26A4/CA2/SLC9A3/SLC26A9/SLC5A1/SLC39A8/SLC2A6/SLC24A3/SLC5A8/SLC7A11/TTYH2/ANO2/LRRC8D/SLCO4A1/CLIC2/SLCO1B1/SLC16A9/SLC25A25/ACE/MFSD2A/SLC6A14/NTRK2/ANO4/TG/CD36/SLC16A4/CLIC3/SLC3A2/IL1A/SLC7A9/SLC12A2/CD47/SLC7A5/LRRC8A/SLC7A1/EDN1/SLC16A14/PLA2G4A/SLC1A5/ATF4/CLIC4/ANXA1/ENPP1/SLC4A9/SLC36A1/TCAF2/LRRC8B/SLCO1B3/SLC26A6/SLC26A11/SLC1A4/ANO8/CEACAM1/SLC16A13/SLCO3A1/TNF/SLC27A4/SLC4A3/SFXN5/ATP8B1/SLC38A1/SLC25A1/CLDN4/LRRC8C/RGS2/SLCO4C1/PTAFR/CLCN6/SLC25A32/SLC5A12/ANO7/SLC25A3/SLC12A4/SLC38A7/SLC16A7/APOL1/SLC9A1/SERINC5/SLC6A9/SLC17A5/P2RY6/SLC9A4/SLC52A2/P2RX4/VDAC2/SNCA/SLC66A1/PRAF2/ANO9/MFSD12/PACC1/GABBR1/SLC16A3/SLC25A23/SLC39A14/SLC35D2/SLC25A22/PRNP/SLC35B4
GOBP_RESPONSE_TO_PEPTIDE 380 0.4231318 1.725881 0.0000010 0.0001109 0.0000911 2755 NTRK1/ANO1/SOCS1/CA2/PNPLA3/EDNRA/TLR4/PTPN22/TRIB3/STC2/PCSK9/INSIG1/PCK2/GJB2/PPARG/MAP1B/KL/NOD2/LPIN1/NR4A1/CPEB2/PRKCQ/CD36/MIR200A/EREG/GDF15/HDAC9/KLF11/TRIM16/MARS1/SOCS2/KLF2/SLC29A2/SESN2/EGR1/CACNB1/EDN1/EGR2/FBP1/GOT1/PTPRE/ANXA1/GRB10/ENPP1/ZBED3/BTG1/NFKBIA/ERFE/RAB8B/CEACAM1/PTGS2/ICAM1/TNF/SLC27A4/MYO1C/SOCS3/IRS2/CAV2/RAB31/NAMPT/APPL2/LTA4H/ZBTB7B/GRB14/EPRS1/BCAR1/FYN/ERRFI1/CCND3/NDEL1/NR4A3/RAB15/CARD9/SLC9A1/JUND/ZDHHC7/STAT1/RIPK2/PIP4K2A/TNFAIP3/SORL1/ASS1/SLC39A14/TIMP1/PRNP/AKT1/KAT2B/TRPV4/DENND4C/MYC/SELENOS/INPPL1/STAT2/GPER1/RELA/SRC/PTPN11/LPIN2/NOD1/ACVR1C/TBC1D4/GPT/DAG1/LPIN3/ABCC1/YWHAG
GOBP_ATTACHMENT_OF_MITOTIC_SPINDLE_MICROTUBULES_TO_KINETOCHORE 14 -0.8776155 -2.152852 0.0000011 0.0001191 0.0000979 356 CDT1/NDC80/CENPE/NUF2/KIF2C
GOBP_MEIOTIC_CELL_CYCLE_PROCESS 154 -0.4915931 -1.916166 0.0000012 0.0001217 0.0001000 1256 SHOC1/KIF18A/RAD54B/ZCWPW1/HSPA2/M1AP/WNT5A/PSMC3IP/CDC25A/RAD54L/BRIP1/FBXO5/MEI1/FMN2/PIWIL2/STAG3/HSF2BP/TRIP13/PTTG1/RAD51AP1/MYBL1/SGO2/TTK/NDC80/FBXO43/CCNB2/NCAPH/NUF2/CCNE2/PLK1/SGO1/CYP26B1/BUB1/DMC1/CDC20/CDC25C/ASPM/TOP2A/CNTD1/BUB1B
GOBP_REGULATION_OF_CELL_ACTIVATION 434 0.4064831 1.687045 0.0000012 0.0001217 0.0001000 2740 FGL2/PLA2G3/EMILIN2/DPP4/SOCS1/C1QTNF1/RASGRP1/SELP/THY1/IL13RA2/CD274/LGALS7B/TLR4/PTPN22/PDCD1LG2/IL1RL1/CNR1/CTSC/PRDM1/SFRP1/CD55/ADAM8/THEMIS2/NOD2/LDLR/IL4I1/PRKCQ/IL31RA/EBI3/IDO1/BCL2/IL1A/UNC13D/TOX/CLCF1/CD47/CD70/GATA3/SLC7A1/TYRO3/APOE/TNFSF13/TICAM1/CD86/MICA/PLA2G4A/CD9/ANXA1/CD276/NECTIN2/HLA-DOB/MFHAS1/TNFSF9/RIPK3/NFKBID/THBD/CARD11/CEACAM1/DUSP10/IL23A/MYD88/TNF/ZC3H12A/AHR/GAB2/DUSP3/CD83/CX3CL1/IRS2/SYT11/HMOX1/SPHK1/ARG2/IL4R/DLG1/PTAFR/ZBTB7B/CCL5/LGALS9/THBS1/FYN/NR4A3/ITGAM/IL15RA/AXL/SH2B3/JUND/SPINK5/SNCA/FADD/IL1RL2/PLSCR1/ACTA2/RIPK2/IL20RB/PRELID1/TEC/TNFAIP3/CD46/TNFRSF13C/MAP3K8/IL15/SHLD2/PRNP/BCL10/CDKN1A/DLG5/SCRIB/AP3D1/HLA-DQB2/PAWR/AKT1/HLA-F/RORA/UBASH3B/GPER1/GAS6/CD177/RUNX1/PDPN/STX4/CGAS/SRC/PTPN11/IL27RA/IL6ST/STXBP2/BCR/LGALS3/RHBDD3/SYK/MYO18A/SLC15A4
GOBP_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE 36 -0.7170824 -2.152611 0.0000016 0.0001499 0.0001232 1161 ABRAXAS1/SPC24/CCNB1/SPAG5/KNL1/CDT1/NDC80/CENPE/NEK2/NUF2/SGO1/KIF2C/SPC25
GOBP_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS 179 0.5064493 1.892106 0.0000015 0.0001499 0.0001232 2650 ALOX15/CYP51A1/MVD/HMGCS1/EBP/PSAT1/FDPS/LSS/DHCR7/SLC7A11/MSMO1/HMGCR/INSIG1/CH25H/PCK2/HSD17B7/KL/IDI1/FGFR4/STARD4/FDFT1/HRH1/SQLE/NSDHL/ACLY/SC5D/ALOX15B/FGF2/G6PD/GATA3/SRD5A3/APOE/TM7SF2/ERG28/GOT1/CYP27B1/MVK/P2RY1/TNF/CDH3/CYP46A1/SPHK1/GCH1/PTAFR/BMP2/HSD3B7/P2RY6/SNCA/ZEB2/ITPKA/DGKQ/MFSD12/DHDDS/PDXK/BMP6/ACER2/DHCR24/ASAH2/CYB5R3/GPER1/OSBPL1A/GFI1/GIPC1/ITPKC/SPTSSA/PTS
GOBP_REGULATION_OF_CHROMOSOME_ORGANIZATION 201 -0.4476498 -1.800467 0.0000015 0.0001499 0.0001232 1101 HECW2/PKIB/FBXO5/INO80B/ANAPC4/CCNB1/TRIP13/AXIN2/PTTG1/ATF7IP2/TTK/CDT1/CDCA5/NDC80/MAD2L1/CENPF/NCAPH/CENPE/NEK2/PLK1/BUB1/DLGAP5/NCAPG/UBE2C/TOP2A/BUB1B
GOBP_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY 193 -0.4608469 -1.847296 0.0000017 0.0001536 0.0001262 4152 H2BC8/H2BC18/NDN/UBN2/SUV39H1/NPM1/H2BC12/TSPYL4/RBBP4/ITGB3BP/BEND3/H3-3A/H1-3/H2AX/H3C6/MCM2/H2BC6/H4C5/CBX3/NAP1L4/SMARCE1/H2BC5/HIRIP3/H4C12/HAT1/FAM172A/SMYD3/H4C6/H2BC4/EZH2/H4C3/H4C2/HDAC5/NASP/MIS18A/H2BC9/NAP1L1/H3C11/H3C1/H2BC11/H3C13/H2BC15/TET1/H4C4/CHAF1B/PADI2/H4C1/M1AP/H3C10/HMGB2/H2BC7/SMARCD3/H2BC3/HELLS/NAP1L3/H4C13/H4C9/ATF7IP2/CENPP/H2BC13/H1-5/H2BC14/H2BC10/H3C7/CENPW/H1-1/ASF1B/H2BC17/H3C12/H3C3/OIP5/HJURP/H3C8/H3C2
GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS 284 0.4515682 1.797230 0.0000017 0.0001536 0.0001262 2749 FGL2/DPP4/C1QTNF1/TNFAIP6/SERPINB4/SERPINB2/PTPRO/RTN4R/SEMA3B/ISG15/PHLDB2/PPARG/FAP/OAS3/NOD2/KLF4/LDLR/NLRC5/FNDC4/OAS1/SLIT2/ST6GAL1/PLAU/SERPINB9/SLC12A2/GPS2/USP18/FGF2/CLASP1/GATA3/TYRO3/ARRB2/APOE/SEMA3D/UFD1/EDN1/MICA/CD9/MVK/HCK/CD200R1/MFHAS1/EPPK1/TRIB1/THBD/METRNL/CEACAM1/DUSP10/PLXNA3/ZFP36/SEMA7A/TNF/SOCS3/DUSP3/CX3CL1/SYT11/CALCRL/SEMA3A/SEMA4C/ARG2/PARP14/LGALS9/SEMA6A/THBS1/FYN/CCN3/SLIT1/GREM1/RNF125/SH2B3/SPINK5/MMP28/ADAR/MICB/TRIM21/IL20RB/NPLOC4/TNFAIP3/SEC14L1/TRAFD1/FURIN/SPP1/HLA-F/RORA/SELENOS/UBASH3B/STAT2/GPER1/DRD1/SRC/MUL1/RHBDF2/PPARD/BCR/ALOX5/SYK/IFI16/SEMA4F
GOBP_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION 51 0.6955870 2.135511 0.0000020 0.0001779 0.0001462 2010 APOBEC3A/RSAD2/ISG15/OAS3/ISG20/OASL/OAS1/MX1/IFIT1/IFITM1/IFIH1/BST2/OAS2/IFITM3/TNF/SHFL/TNIP1/IFIT5/CCL5/PLSCR1/N4BP1/EIF2AK2/APOBEC3B/PARP10/ZNFX1
GOBP_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY 35 -0.7091001 -2.120791 0.0000021 0.0001779 0.0001462 4334 ODAD1/CCDC40/CFAP100/DNAAF11/DRC1/ZMYND10/DNAI3/ODAD4/DNAAF2/CCDC39/DNAI1/DNAAF10/DNAL1/DNAAF3/CCDC65/DNAH7/TEKT2/TTC12/DNAH1/ODAD3/CFAP73/DAW1/DNAI4/DNAAF1/DNAAF4/DNAI2/LRRC49/DNAH2/DNAH5/DNAAF6/DNAAF8/ODAD2
GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 169 0.5050104 1.874634 0.0000021 0.0001779 0.0001462 1588 SH2D1B/NOS2/PLA2G3/RASGRP1/IL13RA2/TLR4/PTPN22/KLK7/RSAD2/CD55/NOD2/PVR/RAET1G/CD36/FZD5/UNC13D/DDX60/CLCF1/SLC7A5/GATA3/TNFSF13/TICAM1/CD86/ANXA1/RAET1E/NECTIN2/COLEC10/IL18R1/NFKBID/ARID5A/IL23A/SEMA7A/TNF/GAB2/HK1/HMOX1/IL4R/PTAFR/APPL2/LGALS9/NR4A3/ITGAM
GOBP_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE 357 0.4208870 1.707012 0.0000021 0.0001779 0.0001462 2968 SH2D1B/PLA2G3/RASGRP1/ZBP1/THY1/C8B/CD274/TLR4/PTPN22/CNR1/KLK7/HMSD/RSAD2/CD55/ADAM8/THEMIS2/LAT2/NOD2/GBP5/NLRC5/PVR/PRKCQ/RAET1G/EREG/IFI35/AIM2/IDO1/BCL2/FZD5/CMTM3/GPS2/CLCF1/CD47/IRF7/GATA3/TNFSF13/CD86/PARP9/PLA2G4A/ANXA1/CD276/RAET1E/NECTIN2/COLEC10/HCK/IL18R1/NFKBID/ARID5A/CARD11/CEACAM1/IL23A/TNF/ZC3H12A/CFB/GAB2/DUSP3/IL4R/PTAFR/APPL2/PRKCH/CCL5/LGALS9/BCAR1/FYN/NLRP10/NR4A3/ITGAM/CARD9/PDE4B/FADD/MICB/PLSCR1/RBCK1/RIPK2/C1S/TEC/CD46/AKIRIN2/ZNFX1/IL15/RAB29/SHLD2/PRNP/BCL10/LIMK1/GBP1/PAWR/PLD2/HLA-F/FCN3/POLR3D/C2/CD177/RELA/TRIM5/STX4/CGAS/SRC/IL27RA/PAK2/IL6ST/LGALS3/SYK/IFI16/SLC15A4/VAV2/SKAP1/CSK/IKBKG/IKBKE/HEXIM1/C4BPA/EXOSC6
GOBP_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA 85 0.6086345 2.069276 0.0000022 0.0001780 0.0001462 2702 CCL26/NOS2/SOCS1/TLR4/CCL4/PPARG/GBP5/NLRC5/CCL22/CD47/EDN1/PARP9/HCK/SLC26A6/TNF/MYO1C/CX3CL1/PARP14/CCL5/LGALS9/EPRS1/GSN/RAB43/STAT1/ASS1/DAPK3/GBP1/MYC/STX4/CCL20/GBP4/CLDN1/PDE12/ACTG1
GOBP_POSITIVE_REGULATION_OF_LOCOMOTION 456 0.4032557 1.676995 0.0000022 0.0001780 0.0001462 2712 CCL26/CCN4/HAS2/TNFAIP6/SELP/THY1/LGR6/CD274/HYAL1/TLR4/CXCL10/PRKD1/HBEGF/CCL4/SEMA3B/CEMIP/SH3RF2/ADAM8/DUOX2/FGFBP1/SLIT2/CXCL8/FLT1/MIR200A/ARTN/NTRK3/HDAC9/CXCL16/F3/BCL2/VEGFA/IL1A/PLAU/NEDD9/RELN/DUOXA2/FGF2/CLASP1/DAPK2/CD47/GATA3/SMOC2/DUOX1/ANXA3/PLA2G7/SEMA3D/ADAM9/EDN1/MET/ANXA1/WASHC1/KITLG/TCAF2/SCARB1/STX3/S100A7/FAM110C/NRP2/HIF1A/SOX9/ROR2/PTGS2/IL23A/KDR/RHOD/SEMA7A/ICAM1/TNF/ZC3H12A/CAMK1D/DDR2/MYO1C/CLDN4/CX3CL1/IRS2/HMOX1/RIPOR1/SPHK1/SEMA3A/SEMA4C/PTAFR/NSMF/EPHA2/BMP2/CCL5/LGALS9/SEMA6A/THBS1/BCAR1/ITGA6/NR4A3/NTN1/SERPINB3/P2RY6/SPAG9/P2RX4/CPNE3/ITGAV/RUFY3/OXSR1/FADD/TJP1/SLC8A1/RAC1/FAM83H/AKT3/ACTA2/RHOB/SCG2/HDAC6/GCNT2/MCU/RHOC/DAPK3/AKT1/JUN/PODXL/LAMB1/TGFBR1/TMSB4X/ADAM17/TRPV4/MYC/GPER1/GAS6/DIAPH1/ITGA3/CD151/PDPN/DRD1/STX4/SRC/HDAC7/RRAS2/CCL20/PLAA/CLDN1/MAPRE2/FERMT1/SHTN1/MIA3/LGALS3/DDRGK1/FUT4/ACTG1/S100A14/TIAM1
GOBP_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 81 0.6111244 2.051251 0.0000026 0.0002053 0.0001687 2546 CCL26/HAS2/ZBP1/IL1R2/HYAL1/CCL4/SFRP1/CXCL8/CCL22/KLF2/EGR1/CD47/HYAL3/EDN1/IL1RN/IRAK2/HIF1A/SOX9/MYD88/ZC3H12A/CX3CL1/RPS6KA4/MAPK11/CCL5/IL1RL2/IRAK1/ST18/GBP1/RORA/MYC/IRAK4/NKX3-1/RELA/CCL20/UPF1
GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS 77 0.6335227 2.114456 0.0000026 0.0002055 0.0001688 2010 APOBEC3A/CH25H/RSAD2/ISG15/OAS3/ISG20/OASL/OAS1/MX1/IFIT1/IFITM1/IFIH1/BST2/OAS2/IFITM3/ZFP36/TNF/SHFL/TNIP1/IFIT5/CCL5/TRIM14/GSN/STAT1/PLSCR1/TRIM21/N4BP1/EIF2AK2/APOBEC3B/TRIM25/PARP10/ZNFX1
GOBP_CHROMOSOME_SEPARATION 88 -0.5688863 -2.021222 0.0000027 0.0002069 0.0001700 1375 SHOC1/M1AP/HECW2/FBXO5/ANAPC4/CCNB1/TRIP13/PTTG1/TTK/CDT1/NDC80/MAD2L1/CENPF/NCAPH/CENPE/PLK1/BUB1/DLGAP5/UBE2C/TOP2A/BUB1B
GOBP_AXONEME_ASSEMBLY 78 -0.5779735 -2.012822 0.0000027 0.0002069 0.0001700 4025 SPEF1/CFAP100/DNAAF11/CFAP157/LRGUK/DRC1/ZMYND10/DNAI3/ODAD4/TOGARAM1/DNAAF2/RSPH4A/DNAJB13/CCDC39/DNAI1/CFAP74/SPAG17/DNAAF10/HYDIN/BBS2/DNAL1/ARMC2/FOXJ1/DNAAF3/SPEF2/CCDC65/RSPH9/DNAH7/CFAP58/TEKT2/CFAP69/CFAP91/CC2D2A/DRC7/SPAG16/CFAP47/TTC12/DNAH1/ODAD3/IQCG/RSPH1/CFAP73/DAW1/CFAP44/CFAP65/DNAI4/DNAAF1/DNAAF4/DNAI2/MNS1/HOATZ/CFAP43/LRRC49/CFAP206/DNAH2/DNAH5/RP1/DNAAF6/DNAAF8/ODAD2/MEIG1/NEURL1
GOBP_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE 169 0.5023979 1.864936 0.0000027 0.0002069 0.0001700 3697 FGL2/TNFAIP6/SERPINB4/ISG15/PPARG/OAS3/NOD2/KLF4/LDLR/NLRC5/FNDC4/OAS1/SERPINB9/GPS2/USP18/GATA3/TYRO3/ARRB2/APOE/UFD1/MICA/MVK/HCK/CD200R1/MFHAS1/METRNL/CEACAM1/DUSP10/ZFP36/SOCS3/CX3CL1/SYT11/CALCRL/ARG2/PARP14/LGALS9/FYN/CCN3/RNF125/SPINK5/ADAR/MICB/TRIM21/IL20RB/NPLOC4/TNFAIP3/SEC14L1/TRAFD1/FURIN/HLA-F/RORA/SELENOS/STAT2/GPER1/SRC/MUL1/RHBDF2/PPARD/BCR/ALOX5/SYK/IFI16/SIRT2/ISL1/CRK/DHX58/MIR149/GIT1/ILRUN/HLA-G/PLK2/CXCL17/NMI/HLA-A/SIRPA/TTLL12/HLA-B/HLA-E/LYN/MAPK7
GOBP_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION 99 -0.5523049 -2.018499 0.0000030 0.0002189 0.0001799 1344 MTBP/INSR/PKMYT1/CCDC8/FBXO5/ANAPC4/CCNB1/TRIP13/EPGN/KIF20B/TTK/CDT1/NDC80/FBXO43/MAD2L1/CENPF/CDCA2/NEK2/PLK1/BUB1/DLGAP5/CDC25C/BUB1B/MKI67
GOBP_LEUKOCYTE_MEDIATED_IMMUNITY 258 0.4507141 1.768009 0.0000034 0.0002481 0.0002039 2416 SH2D1B/NOS2/PLA2G3/RASGRP1/IL13RA2/C8B/SERPINB4/TLR4/CTSC/RSAD2/CD55/LAT2/NOD2/ACE/IL4I1/ULBP1/PVR/RAET1G/SERPINB9/FZD5/UNC13D/CLCF1/CD70/IRF7/GATA3/BST2/ANXA3/ARRB2/TNFSF13/TICAM1/MICA/RAET1E/NECTIN2/ULBP2/HLA-DOB/IL18R1/RIPK3/ARID5A/CEACAM1/IL23A/MYD88/ICAM1/TNF/CEBPG/AHR/GAB2/HMOX1/IL4R/PTAFR/TRPM4/LGALS9/NR4A3/ITGAM/CARD9/RNF19B/TUBB/FADD/CXCL6/ULBP3/IL20RB/C1S/RNF8/CD46/SHLD2/WDR1/BATF/BCL10/HLA-DQB2/HLA-F/ADAM17/IRAK4/C2/CD177
GOBP_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS 226 0.4655340 1.791432 0.0000035 0.0002516 0.0002067 2887 SOCS1/CA2/PNPLA3/EDNRA/TRIB3/PCSK9/INSIG1/PCK2/GJB2/PPARG/MAP1B/KL/LPIN1/NR4A1/CPEB2/PRKCQ/GDF15/HDAC9/MARS1/SOCS2/SLC29A2/EDN1/FBP1/GOT1/PTPRE/GRB10/ENPP1/ERFE/RAB8B/CEACAM1/SLC27A4/MYO1C/SOCS3/IRS2/CAV2/RAB31/NAMPT/APPL2/ZBTB7B/GRB14/EPRS1/BCAR1/ERRFI1/CCND3/NDEL1/NR4A3/RAB15/SLC9A1/ZDHHC7/STAT1/PIP4K2A/SORL1/ASS1/SLC39A14/AKT1/KAT2B/DENND4C/MYC/SELENOS/GPER1/RELA/SRC/PTPN11/LPIN2/TBC1D4/GPT/LPIN3/YWHAG/CSK/CAV1/IGF2
GOBP_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY 464 0.3882675 1.620066 0.0000038 0.0002682 0.0002203 3036 CCL26/NTRK1/ADRA1A/RASGRP1/THY1/EDNRA/FZD10/RGS7/PRKD1/RTN4R/CCL4/SFRP1/PPARGC1B/PPARG/ARHGEF5/CCL22/FLT1/NTRK3/ADPRH/AIM2/F3/VEGFA/NEDD9/BBC3/ARHGAP11B/FGF2/GRHL3/RAP1GAP/CD86/PMAIP1/RGS16/XDH/RIC1/DOCK11/RIPK3/BAK1/BIN1/GMIP/HIP1/ASAP3/PML/MAPK12/ADAP2/TNF/SNX9/FAS/SLC27A4/PPP1R15B/CLDN4/CX3CL1/CAV2/NLRP2/PTAFR/EPHA2/BMP2/ARHGAP27/CCL5/LGALS9/GNA15/CYCS/FYN/RHOG/NDEL1/ITGA6/CARD9/SOX7/SERPINB3/GSN/TBC1D22A/P2RY6/ADAP1/SNCA/FADD/SIPA1L2/RAP1GAP2/TBC1D14/RIPK2/ARHGEF10/PRELID1/AKIRIN2/EVI5L/CHN1/ST18/BCL10/FLCN/LPAR2/ACER2/PIP5K1A/SCRIB/TBC1D10A/GNA12/RHOC/S100A10/AKT1/BOK/SH3BP1/MYC/NGEF/NKX3-1/GPER1/PICALM/CCL20/MUL1/PLAA/RAPGEF4/NOD1/MAPRE2/ACVR1C/BID/BCR/DDRGK1/TBC1D4/SYK/TIAM1/IFI16/TBC1D9/RGP1/TBC1D20/TIAM2/EIF2AK3/RAP1A/DOCK7/CAV1/PRSS22/ARF4/TBC1D16/CASP2/CRK/SIPA1L1/FERMT2/DOCK6/SMCR8/LGMN/PCOLCE2
GOBP_INTRACILIARY_TRANSPORT 36 -0.7029254 -2.110113 0.0000042 0.0002794 0.0002296 3642 IFT20/DYNLT2B/IFT46/ARL3/DYNC2I1/IFT122/IFT43/WDR19/DYNC2LI1/PCM1/RPGR/TUB/TTC21A/IFT57/IFT140/IFT27/LCA5/IFT88/IFT52/IFT74/CILK1/BBS12/IFT81/WDR35/IFT172/DYNC2H1/LCA5L/TTC21B
GOBP_MEIOSIS_I_CELL_CYCLE_PROCESS 98 -0.5423230 -1.980148 0.0000041 0.0002794 0.0002296 1375 SHOC1/RAD54B/ZCWPW1/HSPA2/M1AP/PSMC3IP/CDC25A/RAD54L/BRIP1/FBXO5/MEI1/FMN2/PIWIL2/STAG3/HSF2BP/TRIP13/PTTG1/RAD51AP1/MYBL1/SGO2/NDC80/CCNB2/CCNE2/PLK1/SGO1/DMC1/CDC25C/TOP2A/CNTD1
GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY 164 0.5139272 1.898501 0.0000042 0.0002794 0.0002296 1477 SH2D1B/NOS2/PLA2G3/RASGRP1/IL13RA2/SERPINB4/TLR4/RSAD2/CD55/NOD2/IL4I1/PVR/RAET1G/SERPINB9/FZD5/UNC13D/CLCF1/GATA3/BST2/ARRB2/TNFSF13/TICAM1/MICA/RAET1E/NECTIN2/IL18R1/RIPK3/ARID5A/CEACAM1/IL23A/ICAM1/TNF/AHR/GAB2/HMOX1/IL4R/PTAFR/TRPM4/LGALS9
GOBP_ADAPTIVE_IMMUNE_RESPONSE 285 0.4370658 1.738758 0.0000042 0.0002794 0.0002296 2385 SH2D1B/IL13RA2/C8B/ALOX15/CD274/TLR4/PDCD1LG2/IL1RL1/CTSC/PRDM1/RSAD2/CD55/LAT2/NOD2/IL4I1/PVR/PRKCQ/TAP2/BACH2/EBI3/FZD5/UNC13D/ADCY7/CLCF1/TAP1/CD70/IRF7/GATA3/RAP1GAP/ORAI1/TNFSF13/CD86/MICA/RELB/NFKB2/PLA2G4A/ANXA1/NECTIN2/HLA-DOB/IL18R1/RIPK3/NFKBID/ARID5A/LAMP3/CEACAM1/DUSP10/FCAMR/IL23A/MYD88/ICAM1/TNF/ZC3H12A/AHR/ARG2/IL4R/TRPM4/ZBTB7B/FYN/NLRP10/CARD9/RNF19B/RNF125/TFE3/FADD/CD7/MICB/RAP1GAP2/RIPK2/IL20RB/C1S/RNF8/TEC/TNFAIP3/CD46/TNFRSF13C/SHLD2/BATF/BCL10/HLA-DQB2/HLA-F/ADAM17/RORA/HLA-C/C2
GOBP_RESPONSE_TO_BACTERIUM 422 0.4047564 1.673887 0.0000041 0.0002794 0.0002296 2737 NOS2/EMILIN2/SELP/CD274/STATH/TLR4/LPO/PTPN22/PDCD1LG2/DEFB4A/CXCL10/PRKD1/CNR1/KLK7/PCK2/ISG15/CD55/CXCL11/GJB6/GJB2/IL12RB2/OAS3/IL36G/NOD2/CXCL9/TNIP3/LRAT/GBP5/GSDMC/CMPK2/ACE/NR4A1/OAS1/CXCL8/CD36/ALPL/FOS/IDO1/MAPKAPK3/IL36A/IL1A/FZD5/PRB3/ANXA3/TICAM1/CD86/ADAM9/EDN1/MICA/HPGD/CYP27B1/HERC6/KRT6A/HCK/LY96/OAS2/PI3/TRIB1/IRAK2/ARID5A/SCARB1/NFKBIA/S100A7/THBD/C15orf48/DUSP10/PTGS2/CXCL1/IL23A/ZFP36/MYD88/TNF/ZC3H12A/ADAMTS9/CX3CL1/SYT11/RNF213/ARG2/GCH1/PTAFR/TNIP1/EPHA2/OPTN/BMP2/CCL5/LGALS9/NOCT/NLRP10/CXCL2/LYG1/CARD9/HP/AXL/SLC17A5/JUND/SPINK5/NOS1/SNCA/PDE4B/CXCL6/IRAK1/RBCK1/RIPK2/TNFAIP3/AKIRIN2/WASL/ZNFX1/RAB29/ASS1/BMP6/SBNO2/NFKBIB/BCL10/TMEM255A/CAPN2/IFI44/AKT1/ADAM17/SELENOS/PF4V1/C2/MAPKAPK2/RELA/TRIM5/GFI1/SRC/CCL20/GBP4/PLAA/CLDN1/UPF1/IL27RA/NOD1/CSF2/BCL3/CYP2E1/PPARD/BCR/S100A14/SYK/MARCHF2/FER1L6
GOBP_CHROMATIN_REMODELING 226 -0.4323764 -1.765266 0.0000046 0.0002954 0.0002427 3971 NPM1/H2BC12/PIH1D1/KAT2A/TSPYL4/RBBP4/ITGB3BP/RUVBL1/RBBP7/ACTL6A/H3-3A/H1-3/HCFC2/H2AX/H3C6/MCM2/H2BC6/FOXA1/H4C5/CBX3/SMARCA2/ACTR6/NAP1L4/SMARCE1/H2BC5/H4C12/RUVBL2/SMYD3/ANP32E/H4C6/H2BC4/ESR1/H4C3/H4C2/HDAC5/NASP/MIS18A/H2BC9/NAP1L1/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/CHAF1B/H4C1/H3C10/HMGB2/H2BC7/SMARCD3/H2BC3/HELLS/INO80B/NAP1L3/H4C13/H4C9/CHD1L/CENPP/H2BC13/H1-5/H2BC14/H2BC10/H3C7/MYB/CENPW/H1-1/ASF1B/H2BC17/H3C12/H3C3/OIP5/HJURP/H3C8/H3C2
GOBP_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT 358 0.4207143 1.705542 0.0000053 0.0003416 0.0002806 2809 NTRK1/PLA2G3/ARC/THY1/PMP22/PTPRO/PRKD1/RTN4R/SDC2/CNR1/BDNF/SEMA3B/SFRP1/CRMP1/MAP1B/KLF4/NTNG1/ALKAL1/MFSD2A/SLIT2/NTRK2/NTRK3/MAP2/PPP2R5B/VEGFA/TNIK/TOX/RELN/EPHB3/LRP8/ZNF365/GATA3/APOE/SEMA3D/TWF2/CHODL/PRAG1/EPHA3/DAB1/BRSK2/ROR2/PLXNA3/SEMA7A/CAMK1D/NRCAM/FZD1/LRRC7/CX3CL1/ISLR2/DBN1/SEMA3A/SEMA4C/RGS2/ATP8A2/NSMF/BRSK1/SEMA6A/MARK1/FYN/SLIT1/NDEL1/ITGA6/FKBP1B/NTN1/NDRG4/RUFY3/ARSB/DENND5A/EHD1/PTPRG/CSMD3/ITPKA/PTPN9/TENM3/RAB29/CHN1/ACAP3/PTK6/SPP1/PDLIM5/MBOAT1/LIMK1/AKT1/EFNA5/TRPV4/NGEF/PARP6/NEDD4/SHANK3/SCN1B/GFI1/ITGA3/MCF2/FGF13/EPHA7/PAK2/SHTN1/STK25/MAP2K1/CFL1/COBL/TIAM1/SEMA4F/TIAM2/RAP1A
GOBP_DNA_REPLICATION_DEPENDENT_CHROMATIN_ORGANIZATION 29 -0.7331369 -2.134667 0.0000057 0.0003581 0.0002942 2521 H3C6/H4C5/H4C12/HAT1/H4C6/H4C3/H4C2/NASP/H3C11/H3C1/H4C4/CHAF1B/H4C1/H3C10/H4C13/H4C9/H3C7/ASF1B/H3C12/H3C3/H3C8/H3C2
GOBP_MEIOTIC_CHROMOSOME_SEGREGATION 72 -0.5754061 -1.982625 0.0000058 0.0003642 0.0002992 2602 MAPK15/HORMAD1/MRE11/SMC4/NDC1/SMC2/CENPS/ESPL1/SHOC1/ZCWPW1/M1AP/PSMC3IP/BRIP1/FMN2/STAG3/TRIP13/PTTG1/SGO2/TTK/NCAPH/NUF2/CCNE2/PLK1/SGO1/BUB1/DMC1/TOP2A/BUB1B
GOBP_CENTROMERIC_SISTER_CHROMATID_COHESION 11 -0.8904920 -2.024711 0.0000062 0.0003820 0.0003138 677 AXIN2/SGO2/SGO1/BUB1/BUB1B
GOBP_CILIUM_MOVEMENT 137 -0.4876382 -1.866628 0.0000074 0.0004513 0.0003708 3581 DRC1/ZMYND10/CFAP251/DNAI3/CFAP20/TTC29/ROPN1B/SLC22A16/ENO4/ODAD4/TEKT3/DNAAF2/TEKT5/RSPH4A/CCDC39/CFAP54/DNAI1/SPAG17/HYDIN/BBS2/ARMC2/CFAP52/KIF27/KATNIP/ZBBX/DPCD/SPEF2/CCDC65/TTC21A/RSPH9/GAS2L2/DNAH7/CFAP58/ROPN1L/TEKT2/CFAP61/CFAP69/CFAP91/DRC7/INPP5B/SPAG16/CFAP47/SPA17/TTC12/DNAH9/DNAH1/ODAD3/SLC26A8/IQCG/NME5/CFAP73/DAW1/CFAP221/CFAP44/AQP4/RFX3/CFAP65/PLTP/DNAI4/DNAAF1/DNAAF4/TEKT1/DNAI2/BBS4/MNS1/HOATZ/CFAP70/TCTE1/CFAP43/CFAP45/CFAP206/TEKT4/TTLL6/DNAH5/DNAAF6/CFAP53/ODAD2/NEK10/MEIG1/NEURL1/CATSPERD/EPPIN
GOBP_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE 140 0.5220207 1.902048 0.0000081 0.0004801 0.0003944 2603 CCL26/NTRK1/ADRA1A/RASGRP1/ALOX15/TLR4/PTPN22/CCL4/CD44/NOD2/FGFR4/ALKAL1/CCL22/NTRK2/CD36/NTRK3/IL1A/FGF2/ARRB2/APOE/CAVIN3/P2RY1/MFHAS1/S100A7/ROR2/KDR/SEMA7A/ICAM1/TNF/CX3CL1/BMP2/CCL5/LGALS9/CARD9/ABCA7/NDRG4/P2RY6/ACTA2/RIPK2/GAREM1/GCNT2/JUN/TRPV4/GPER1/GAS6/SRC/PTPN11/CCL20/ARHGAP8/NOD1/PRXL2C
GOBP_VIRAL_PROCESS 357 0.4086153 1.657241 0.0000080 0.0004801 0.0003944 3386 APOBEC3A/CCL4/CH25H/RSAD2/ISG15/CD55/OAS3/ISG20/OASL/LDLR/ANPEP/NPC1/OAS1/CXCL8/PVR/MX1/IFIT1/ST6GAL1/SLC3A2/BCL2/IFITM1/IFIH1/STOM/IRF7/BST2/TYRO3/APOE/CD86/PARP9/SLC1A5/IFI27/NECTIN2/OAS2/TMPRSS2/SCARB1/LAMP3/VPS37B/IFITM3/ZFP36/VPS37D/ICAM1/TNF/ZC3H12A/IGF2R/RNASEK/CAV2/SHFL/TNIP1/IFIT5/EPHA2/CCL5/ST3GAL4/LGALS9/TRIM14/SERPINB3/GSN/AXL/SLC52A2/ITGAV/TPCN2/ADAR/RAB43/STAT1/PLSCR1/TRIM21/N4BP1/MGAT4B/EIF2AK2/APOBEC3B/EDEM2/TRIM25/CLDN9/CD46/NECTIN4/CHMP6/PARP10/ITGB7/ZNFX1/RAB29/ITGB6/FURIN/CHMP7/JUN/PCBP1/FCN3/NEDD4/GAS6/SLC20A2/TMPRSS4/TRIM5/GFI1/CLDN1/TMEM41B/EPS15/CALCOCO2/PDE12/CFL1/IFI16/DAG1/LARP1/TBC1D20/CCNK/SMPD1/CAV1/HEXIM1/SRPK1/TRIM22/PKN2/VPS4A/DENR/RAD23A/VPS4B/CHMP1B/CSNK1A1/TFRC/P4HB/CD81/ATG7/SNF8/TP53
GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE 253 0.4503913 1.761187 0.0000083 0.0004864 0.0003996 2753 PLA2G3/CCN4/TNFAIP6/ZBP1/ALOX15/NCF1/TLR4/IL1RL1/CNR1/CTSC/ADAM8/PPARG/NOD2/KLF4/LDLR/DUOXA1/ACE/FNDC4/IFI35/IDO1/GPS2/DUOXA2/USP18/CD47/GATA3/TYRO3/PLA2G7/APOE/ANXA1/MVK/HCK/CD200R1/OSMR/MFHAS1/NFKBIA/METRNL/DUSP10/PTGS2/IL23A/ZFP36/MYD88/SEMA7A/TNF/PSMA6/SOCS3/CX3CL1/SYT11/CALCRL/SPHK1/TNIP1/CCL5/FYN/NLRP10/CCN3/SNCA/IL1RL2/IL20RB/TNFAIP3/IL15/CELF1/FURIN/SBNO2/C2CD4B/TMSB4X/RORA/TRPV4/SELENOS/GPER1/RELA/CYLD/SRC/RHBDF2/BIRC3/NEAT1/PPARD/IL6ST/BCR/MAPK13/ALOX5/RHBDD3/SYK/ABCC1
GOBP_POSITIVE_REGULATION_OF_GTPASE_ACTIVITY 221 0.4642299 1.782950 0.0000094 0.0005404 0.0004440 3004 CCL26/NTRK1/RASGRP1/THY1/FZD10/RGS7/RTN4R/CCL4/SFRP1/ARHGEF5/CCL22/NTRK3/ADPRH/NEDD9/ARHGAP11B/GRHL3/RAP1GAP/RGS16/RIC1/DOCK11/BIN1/GMIP/ASAP3/ADAP2/SNX9/SLC27A4/CX3CL1/CAV2/EPHA2/ARHGAP27/CCL5/RHOG/NDEL1/ITGA6/TBC1D22A/ADAP1/SIPA1L2/RAP1GAP2/TBC1D14/ARHGEF10/EVI5L/CHN1/FLCN/PIP5K1A/SCRIB/TBC1D10A/S100A10/SH3BP1/NGEF/PICALM/CCL20/RAPGEF4/MAPRE2/BCR/TBC1D4/TIAM1/TBC1D9/RGP1/TBC1D20/TIAM2/RAP1A/DOCK7/TBC1D16/CRK/SIPA1L1/FERMT2/DOCK6/SMCR8
GOBP_SECONDARY_ALCOHOL_METABOLIC_PROCESS 114 0.5501689 1.943323 0.0000101 0.0005668 0.0004656 1710 CYP51A1/MVD/HMGCS1/EBP/FDPS/LSS/PCSK9/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/LDLR/FDFT1/NPC1/SQLE/NSDHL/ACLY/SC5D/NFE2L1/LCAT/G6PD/APOE/TM7SF2/CYP27B1/MVK/SCARB1/IDH1/APOL2/CYP46A1/SREBF2/APOBR/CYP2C9/APOL1/ACADL/GBA2
GOBP_POSITIVE_REGULATION_OF_CELL_DEATH 483 0.3757656 1.573527 0.0000101 0.0005668 0.0004656 2607 NTRK1/NOS2/IL19/EMILIN2/ZBP1/CD274/TLR4/SPDEF/FZD9/PCSK9/CNR1/CTSC/IFIT2/SFRP1/ADAM8/PPARG/FAP/ALDH1A3/ACE/GADD45G/NR4A1/SLIT2/PHLDA2/CD36/MIR200A/TNFRSF10A/UBD/FOS/KLF11/IDO1/DDIT3/BBC3/OLFM1/EGR1/PLEKHN1/TNFSF12/DAPK2/EEF1A2/ARRB2/UBE2Z/PMAIP1/HPGD/TNFRSF12A/ATF4/OSGIN1/ANXA1/BTG1/RIPK3/BAK1/BIN1/MSX2/RNF122/PML/SYCE3/FOSL1/PTGS2/TNF/ZC3H12A/CAMK1D/FAS/SLC27A4/IGF2R/PEA15/HMOX1/ASCL1/ID3/STK17B/BMP2/CCL5/LGALS9/THBS1/FYN/GADD45A/E2F3/ITGA6/ITGAM/DUSP6/HP/SLC9A1/GSN/SNCA/FADD/VDR/TNFRSF10C/RBCK1/RIPK2/ADCY10/AIFM2/MAP3K9/PRELID1/RHOB/ATF3/HDAC6/LATS2/TP53BP2/CDKN2A/CELF1/DCUN1D3/PHLDA1/PRNP/BCL10/FLCN/ACER2/SQSTM1/CDKN1A/CAPN2/SCRIB/LTBR/DAPK3/PAWR/JUN/BOK/TGFBR1/MYC/NKX3-1/GPER1/GRIK2/EIF4G1/PICALM/CYLD/SRC/PLAGL2/NOD1/TIGAR/EPHA7/ACVR1C/BID/PAK2
GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE 199 0.4696394 1.778314 0.0000107 0.0005961 0.0004897 2753 SH2D1B/PLA2G3/CCN4/EMILIN2/RASGRP1/ZBP1/TLR4/IL1RL1/CNR1/KLK7/CTSC/ADAM8/NOD2/GBP5/LDLR/ACE/NLRC5/PVR/RAET1G/EREG/IFI35/AIM2/IDO1/CD47/IRF7/PLA2G7/PARP9/RAET1E/NECTIN2/HCK/OSMR/NFKBIA/PTGS2/IL23A/TNF/CX3CL1/TNIP1/OPTN/CCL5/FYN/NLRP10/CARD9/SNCA/FADD/PLSCR1/RIPK2/AKIRIN2/ZNFX1/IL15/C2CD4B/HLA-F/TRPV4/POLR3D/TRIM5/CGAS/SRC/NOD1/NEAT1/PAK2/IL6ST/MAPK13/SYK/IFI16/SLC15A4/ABCC1
GOBP_CELLULAR_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN 154 0.5141361 1.878411 0.0000116 0.0006371 0.0005234 2637 NOS2/CD274/TLR4/PTPN22/PDCD1LG2/CXCL10/CD55/CXCL11/IL36G/NOD2/CXCL9/TNIP3/CMPK2/CXCL8/CD36/IL36A/IL1A/FZD5/TICAM1/CD86/ADAM9/HCK/LY96/TRIB1/IRAK2/ARID5A/SCARB1/NFKBIA/CXCL1/ZFP36/MYD88/TNF/ZC3H12A/CX3CL1/PTAFR/TNIP1/CCL5/CXCL2/AXL/PDE4B/CXCL6/IRAK1/RIPK2/TNFAIP3/ASS1/BMP6/SBNO2/NFKBIB/BCL10/CAPN2/AKT1/SELENOS/PF4V1/RELA/TRIM5/GFI1/SRC/PLAA/UPF1/CSF2/PPARD/BCR
GOBP_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN 247 0.4465857 1.743580 0.0000132 0.0007176 0.0005895 2637 NOS2/SELP/CD274/TLR4/PTPN22/PDCD1LG2/CXCL10/CNR1/PCK2/CD55/CXCL11/GJB6/GJB2/IL12RB2/IL36G/NOD2/CXCL9/TNIP3/CMPK2/ACE/NR4A1/CXCL8/CD36/ALPL/FOS/IDO1/MAPKAPK3/IL36A/IL1A/FZD5/TICAM1/CD86/ADAM9/EDN1/HPGD/CYP27B1/HCK/LY96/TRIB1/IRAK2/ARID5A/SCARB1/NFKBIA/S100A7/THBD/DUSP10/PTGS2/CXCL1/ZFP36/MYD88/TNF/ZC3H12A/CX3CL1/GCH1/PTAFR/TNIP1/CCL5/LGALS9/NOCT/CXCL2/CARD9/AXL/JUND/NOS1/SNCA/PDE4B/CXCL6/IRAK1/RIPK2/TNFAIP3/AKIRIN2/ASS1/BMP6/SBNO2/NFKBIB/BCL10/CAPN2/AKT1/ADAM17/SELENOS/PF4V1/C2/MAPKAPK2/RELA/TRIM5/GFI1/SRC/PLAA/CLDN1/UPF1/CSF2/PPARD/BCR
GOBP_RESPONSE_TO_PEPTIDE_HORMONE 304 0.4243774 1.698754 0.0000134 0.0007179 0.0005898 2755 SOCS1/CA2/PNPLA3/EDNRA/TRIB3/STC2/PCSK9/INSIG1/PCK2/GJB2/PPARG/MAP1B/KL/LPIN1/NR4A1/CPEB2/PRKCQ/EREG/GDF15/HDAC9/TRIM16/MARS1/SOCS2/SLC29A2/SESN2/EGR1/EDN1/EGR2/FBP1/GOT1/PTPRE/ANXA1/GRB10/ENPP1/ZBED3/BTG1/ERFE/RAB8B/CEACAM1/PTGS2/SLC27A4/MYO1C/SOCS3/IRS2/CAV2/RAB31/NAMPT/APPL2/LTA4H/ZBTB7B/GRB14/EPRS1/BCAR1/ERRFI1/CCND3/NDEL1/NR4A3/RAB15/SLC9A1/JUND/ZDHHC7/STAT1/PIP4K2A/SORL1/ASS1/SLC39A14/TIMP1/AKT1/KAT2B/TRPV4/DENND4C/MYC/SELENOS/INPPL1/STAT2/GPER1/RELA/SRC/PTPN11/LPIN2/ACVR1C/TBC1D4/GPT/DAG1/LPIN3/YWHAG
GOBP_SPINDLE_ORGANIZATION 184 -0.4427487 -1.752716 0.0000143 0.0007592 0.0006237 2042 EFHC2/CENPH/RACGAP1/MAP10/AUNIP/ESPL1/EFHC1/KIZ/STIL/GOLGA8M/STMN1/ABRAXAS1/WDR62/STARD9/KIF11/PSRC1/FBXO5/CCNB1/KIFC1/KIF4A/SPAG5/TTK/NDC80/TPX2/CCNB2/CENPE/NEK2/NUF2/PLK1/KIF15/GOLGA8H/CDC20/DLGAP5/ASPM/SPC25/MYBL2
GOBP_VIRAL_LIFE_CYCLE 267 0.4337696 1.711075 0.0000157 0.0008224 0.0006756 2795 APOBEC3A/CH25H/RSAD2/ISG15/CD55/OAS3/ISG20/OASL/LDLR/ANPEP/NPC1/OAS1/CXCL8/PVR/MX1/IFIT1/SLC3A2/BCL2/IFITM1/IFIH1/STOM/BST2/TYRO3/APOE/CD86/SLC1A5/IFI27/NECTIN2/OAS2/TMPRSS2/SCARB1/LAMP3/VPS37B/IFITM3/VPS37D/ICAM1/TNF/ZC3H12A/RNASEK/CAV2/SHFL/TNIP1/IFIT5/EPHA2/CCL5/LGALS9/TRIM14/SERPINB3/GSN/AXL/SLC52A2/ITGAV/TPCN2/ADAR/RAB43/PLSCR1/TRIM21/N4BP1/EIF2AK2/APOBEC3B/TRIM25/CLDN9/CD46/NECTIN4/CHMP6/PARP10/ITGB7/ZNFX1/RAB29/ITGB6/FURIN/CHMP7/PCBP1/FCN3/NEDD4/GAS6/SLC20A2/TMPRSS4/TRIM5/CLDN1/TMEM41B/EPS15/PDE12/IFI16/DAG1/LARP1/TBC1D20/CCNK/SMPD1
GOBP_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS 180 0.4872539 1.822410 0.0000162 0.0008235 0.0006765 2805 NOS2/CD274/TLR4/PTPN22/PDCD1LG2/CXCL10/CD55/CXCL11/IL36G/NOD2/CXCL9/TNIP3/CMPK2/CXCL8/CD36/IL36A/IL1A/DDIT3/FZD5/TICAM1/CD86/ADAM9/HCK/LY96/TRIB1/IRAK2/ARID5A/SCARB1/NFKBIA/CXCL1/ZFP36/MYD88/TNF/ZC3H12A/PPP1R15B/CX3CL1/PTAFR/TNIP1/CCL5/CXCL2/AXL/PDE4B/SLX4/CXCL6/IRAK1/RIPK2/TNFAIP3/ASS1/BMP6/SBNO2/NFKBIB/BCL10/CAPN2/AKT1/SELENOS/PF4V1/MUS81/RELA/TRIM5/GFI1/SRC/PLAA/UPF1/CSF2/TIGAR/PPARD/BCR/WFS1/SYK/SIRT2/EIF2AK3
GOBP_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS 145 -0.4666049 -1.795729 0.0000162 0.0008235 0.0006765 3165 TOGARAM1/MAP9/DYNLT1/HSPA1A/CHEK2/PIBF1/GPSM2/AURKA/KIF23/TOGARAM2/CEP97/SAPCD2/PKHD1/EFHC2/CENPH/RACGAP1/MAP10/ESPL1/EFHC1/STIL/ANKFN1/STMN1/ABRAXAS1/WDR62/KIF11/PSRC1/CCNB1/GJA1/KIFC1/KIF4A/TTK/NDC80/MAD2L1/TPX2/CENPE/NEK2/NUF2/PLK1/KIF15/CDC20/DLGAP5/SPC25/MYBL2
GOBP_RESPONSE_TO_INSULIN 210 0.4636959 1.769580 0.0000162 0.0008235 0.0006765 2755 SOCS1/PNPLA3/TRIB3/PCSK9/INSIG1/PCK2/PPARG/KL/LPIN1/CPEB2/PRKCQ/HDAC9/MARS1/SLC29A2/SESN2/EGR1/EGR2/FBP1/GOT1/PTPRE/GRB10/ENPP1/ZBED3/ERFE/RAB8B/CEACAM1/SLC27A4/MYO1C/SOCS3/IRS2/CAV2/RAB31/NAMPT/APPL2/ZBTB7B/GRB14/EPRS1/BCAR1/ERRFI1/CCND3/NDEL1/RAB15/SLC9A1/ZDHHC7/STAT1/PIP4K2A/SORL1/SLC39A14/AKT1/KAT2B/TRPV4/DENND4C/MYC/SELENOS/INPPL1/SRC/PTPN11/LPIN2/ACVR1C/TBC1D4/GPT/LPIN3/YWHAG
GOBP_MITOTIC_SPINDLE_ORGANIZATION 122 -0.4857442 -1.814493 0.0000173 0.0008690 0.0007139 2042 EFHC2/CENPH/RACGAP1/MAP10/EFHC1/STIL/STMN1/ABRAXAS1/WDR62/KIF11/PSRC1/CCNB1/KIFC1/KIF4A/TTK/NDC80/TPX2/CENPE/NEK2/NUF2/PLK1/KIF15/CDC20/DLGAP5/SPC25/MYBL2
GOBP_POSITIVE_REGULATION_OF_MAPK_CASCADE 359 0.4052114 1.643886 0.0000184 0.0009143 0.0007511 1935 CCL26/NTRK1/ADRA1A/ADRA2C/C1QTNF1/RASGRP1/ALOX15/FZD10/NCF1/TLR4/PTPN22/CCL4/SH3RF2/CD44/ADAM8/KL/NOD2/FGFR4/ARHGEF5/ALKAL1/MAPK8IP2/GADD45G/CCL22/NTRK2/FLT1/CD36/GDF15/NTRK3/VEGFA/TNIK/IL1A/EDAR/FZD5/FGF2/ARRB2/APOE/ADAM9/EDN1/CAVIN3/XDH/P2RY1/KITLG/FGD2/MFHAS1/S100A7/TMEM106A/ROR2/KDR/MYD88/SEMA7A/ICAM1/TNF/ZC3H12A/ANKRD6/CX3CL1/CAV2/LIF/SPHK1/KLB/SEMA3A/SEMA4C/DOK4/BMP2/CCL5/LGALS9/THBS1/TNFRSF19/GADD45A/SOX2/CARD9/ABCA7/NDRG4/MST1R/P2RY6/SPAG9/EIF2AK2/IRAK1/ACTA2/TGFA/RIPK2/TRAF5/GAREM1/PLCE1
GOBP_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS 230 0.4510083 1.738560 0.0000218 0.0010733 0.0008817 2787 CISH/SOCS1/PNPLA3/ALOX15/MVD/HMGCS1/FDPS/IDI1/FADS1/LPIN1/MFSD2A/PLA2G4C/ABHD4/SOCS2/LCAT/LIPH/FGF2/SRD5A3/PLA2G4A/MVK/SERAC1/GPAT3/LPCAT4/FAR1/IDH1/SOCS3/PISD/TMEM150A/SGMS1/PIGW/SERINC5/PTPMT1/SELENOI/SAMD8/PLSCR1/ITPKA/GPAT4/PGAP4/PIP4K2A/DGKQ/DHDDS/TAFAZZIN/ACP6/CAPN2/PIP5K1A/INPP1/MBOAT1/PIK3C2B/PLD2/INPPL1/DGKA/PTDSS1/CHP1/PITPNM2/ITPKC/PPARD/DOLK/TTC7A/ABHD3/ACSL3
GOBP_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEGREGATION 42 -0.6580110 -2.032223 0.0000223 0.0010848 0.0008912 918 FBXO5/CCNB1/TRIP13/PTTG1/TTK/CDT1/NDC80/MAD2L1/CENPF/PLK1/BUB1/BUB1B
GOBP_PHOSPHOLIPID_METABOLIC_PROCESS 328 0.4122127 1.662908 0.0000238 0.0011442 0.0009400 2795 CISH/PLA2G3/SOCS1/PNPLA3/APOC1/ALOX15/MVD/HMGCS1/FDPS/LIPG/PCSK9/IDI1/FADS1/LDLR/FDFT1/LPIN1/MFSD2A/PLA2G4C/ABHD4/ENPP6/ALOX15B/SOCS2/PLAAT1/LCAT/LIPH/FGF2/SRD5A3/PLA2G7/PLA2G4A/GPCPD1/MVK/SCARB1/SERAC1/GPAT3/LPCAT4/FAR1/IDH1/SOCS3/PISD/PLCB3/ABCA3/TMEM150A/SGMS1/PIGW/SERINC5/PTPMT1/SELENOI/SNCA/SAMD8/PLSCR1/ITPKA/GPAT4/PGAP4/PIP4K2A/DGKQ/DHDDS/TAFAZZIN/ACP6/GDPD3/CAPN2/PIP5K1A/INPP1/MBOAT1/PIK3C2B/PLD2/MTMR12/INPPL1/DGKA/SGPP1/PTDSS1/CHP1/PIP4P1/PLAA/PITPNM2/ITPKC/PPARD/DOLK/TTC7A/ABHD3/OSBPL5/ACSL3/SMPD1
GOBP_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS 172 0.4911855 1.818663 0.0000245 0.0011654 0.0009574 2755 SOCS1/PNPLA3/TRIB3/PCSK9/INSIG1/PCK2/PPARG/KL/LPIN1/CPEB2/PRKCQ/HDAC9/MARS1/SLC29A2/FBP1/GOT1/PTPRE/GRB10/ENPP1/ERFE/RAB8B/CEACAM1/SLC27A4/MYO1C/SOCS3/IRS2/CAV2/RAB31/NAMPT/APPL2/ZBTB7B/GRB14/EPRS1/BCAR1/ERRFI1/CCND3/NDEL1/RAB15/SLC9A1/ZDHHC7/STAT1/PIP4K2A/SORL1/SLC39A14/AKT1/KAT2B/DENND4C/MYC/SELENOS/SRC/PTPN11/LPIN2/TBC1D4/GPT/LPIN3/YWHAG
GOBP_CHROMOSOME_CONDENSATION 40 -0.6503274 -1.994619 0.0000249 0.0011693 0.0009606 363 H1-5/CDCA5/H1-1/NCAPH/PLK1/CDK1/NCAPG/TOP2A
GOBP_REGULATION_OF_HORMONE_LEVELS 352 0.4029557 1.634388 0.0000250 0.0011693 0.0009606 2372 NOS2/ANO1/PLA2G3/TRPV6/SLC5A5/DPP4/C1QTNF1/ADCY5/SLC9B2/STC2/PCSK6/DHCR7/CNR1/SFRP1/PCK2/ADH1C/HSD17B7/PPARG/DUOX2/SLCO4A1/LRAT/SLCO1B1/ALDH1A3/DUOXA1/ACE/FOXD1/IL4I1/CYP2S1/TG/GCNT4/DUOXA2/EGR1/SLC7A5/RDH11/LRRC8A/GATA3/DUOX1/CPT1A/SRD5A3/PLA2G7/EDN1/IL1RN/DOC2B/CYP27B1/ANXA1/RAB11FIP1/P2RY1/SDR16C5/HSD17B12/STX1A/HIF1A/DHRS7/BRSK2/RAB8B/TNF/CYP2C18/NIBAN2/CYP46A1/IRS2/LIF/RETSAT/GPR27/TRPM4/ECE1/BMP2/CCL5/CCN3/BACE2/FKBP1B/CYP2C9/ACSL4/SLC8B1/RDH13/AACS/CYP3A5/DGKQ/PCSK7/VSNL1/LTBP4/GABBR1/SLC39A14/SGPL1/BMP6/FURIN/PIM3/MCU/EIPR1/TFR2/SPP1/ATP1A1/EFNA5/RAB11FIP5/TRPV4/NKX3-1/GPER1
GOBP_MONONUCLEAR_CELL_DIFFERENTIATION 310 0.4158197 1.675708 0.0000253 0.0011718 0.0009626 2403 NTRK1/FGL2/SOCS1/RASGRP1/PTPN22/FZD9/BATF3/PRDM1/SFRP1/MT1G/RSAD2/ADAM8/PPARG/BATF2/RUNX2/BCL11B/IL4I1/KLF6/DLL4/IL31RA/UBD/HDAC9/HHEX/BCL2/VEGFA/IL1A/FZD5/TOX/GPS2/EGR1/CLCF1/FASN/LRRC8A/IRF7/GATA3/TYRO3/CD86/RELB/ANXA1/DOCK11/TNFSF9/IL18R1/RIPK3/NFKBID/BAK1/IKZF1/CARD11/DUSP10/ITGB8/IL23A/NFIL3/CEBPG/ZC3H12A/CD83/IL4R/CMTM7/ZBTB7B/LGALS9/IL15RA/AXL/SPINK5/FADD/IL1RL2/MYH9/RIPK2/PRELID1/CD46/IL15/BATF/ITGB6/LTBR/PIR/AP3D1/JUN/ADAM17/RORA/MYC/GAS6/JMJD6
GOBP_MICROTUBULE_BUNDLE_FORMATION 106 -0.5011331 -1.852092 0.0000272 0.0012471 0.0010245 3199 ODAD4/TOGARAM1/DNAAF2/RSPH4A/DNAJB13/CCDC66/CCDC39/DNAI1/CFAP74/SPAG17/DNAAF10/HYDIN/BBS2/DNAL1/ARMC2/FOXJ1/DNAAF3/SPEF2/CCDC65/RSPH9/GAS2L2/DNAH7/CFAP58/TEKT2/CFAP69/CFAP91/CC2D2A/NCKAP5/DRC7/TPPP3/SPAG16/CFAP47/TTC12/DNAH1/ODAD3/IQCG/RSPH1/CFAP73/DAW1/CFAP44/CFAP65/DNAI4/DNAAF1/DNAAF4/DNAI2/MNS1/HOATZ/CFAP43/LRRC49/CFAP206/DNAH2/PSRC1/TTLL6/DNAH5/RP1/DNAAF6/DNAAF8/CAPN6/ODAD2/MEIG1/NEURL1/PLK1/KIF20A
GOBP_EXTRACELLULAR_TRANSPORT 42 -0.6545712 -2.021599 0.0000278 0.0012622 0.0010370 3199 ODAD4/DNAAF2/CCDC39/CFAP54/DNAI1/SPAG17/KIF27/KATNIP/DPCD/SPEF2/ROPN1L/SPAG16/SPA17/DNAH9/DNAH1/NME5/DAW1/CFAP221/AQP4/RFX3/DNAAF1/DNAAF4/CFAP43/CFAP45/DNAH5/CFAP53/NEK10
GOBP_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT 15 0.8591812 2.035969 0.0000286 0.0012837 0.0010546 1361 NTRK1/GDNF/EDNRA/GATA3/NRP2/ASCL1/SEMA3A
GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 124 0.5270369 1.884621 0.0000309 0.0013748 0.0011294 926 SH2D1B/EMILIN2/RASGRP1/ZBP1/CD274/TLR4/KLK7/ADAM8/NOD2/OASL/GBP5/NLRC5/PVR/RAET1G/EREG/IFI35/AIM2/DDX60/IRF7/PARP9/RAET1E/NECTIN2/HCK/LY96
GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION 344 0.4009114 1.622603 0.0000339 0.0014801 0.0012159 2622 NOS2/PLA2G3/RASGRP1/CD274/TLR4/PTPN22/IL1RL1/RSAD2/ISG15/CD55/ADAM8/IL12RB2/OAS3/NOD2/LUM/GBP5/OAS1/PRKCQ/RAET1G/CD36/EREG/AIM2/EBI3/F3/TRIM16/IDO1/IL36A/ALOX15B/IFIH1/IL1A/DDIT3/FZD5/EGR1/SLC7A5/IRF7/GATA3/TICAM1/CD86/LURAP1/ATF4/SERPINB7/ANXA1/CD276/LY96/OAS2/IL18R1/ARID5A/PANX2/HIF1A/CARD11/TMEM106A/PTGS2/IL23A/MYD88/SEMA7A/TNF/CEBPG/SULF1/CD83/CX3CL1/HK1/HMOX1/SPHK1/NLRP2/IL4R/PTAFR/MAPK11/ZBTB7B/LGALS9/THBS1/NLRP10/NR4A3/CARD9/PDE4B/FADD/IL1RL2/STAT1/EIF2AK2/IRAK1/RIPK2/IL20RB/CD46/AKIRIN2/SORL1/IL15/SULF2/BATF/FURIN/BCL10/SCRIB/HLA-F/ADAM17/RORA/TRPV4/POLR3D/MAPKAPK2/RELA/RUNX1/CGAS/SRC/PTPN11/IL27RA/NOD1/CSF2/BCL3/FERMT1/IL6ST
GOBP_DNA_REPLICATION 266 -0.3821122 -1.581945 0.0000338 0.0014801 0.0012159 2429 LRWD1/RFC5/WDHD1/MRE11/JADE1/NASP/ATAD5/ZRANB3/CHTF8/NAP1L1/CENPS/CCNA2/RRM1/CHEK1/DNA2/RPA3/POLE2/POLI/LIG1/ZGRF1/CHAF1B/CDC7/MCM8/BLM/POLN/GINS1/GINS2/POLA2/FBXO5/RECQL4/GLI2/INO80B/ORC1/POLQ/MCIDAS/PCLAF/E2F7/DSCC1/CDT1/GMNN/DACH1/CCNE2/TICRR/GMNC/CDK1/RRM2/DTL/MCM10/ESCO2/FAM111B/ADRA2A
GOBP_STEROID_BIOSYNTHETIC_PROCESS 129 0.5114956 1.836594 0.0000360 0.0015568 0.0012790 1471 CYP51A1/MVD/HMGCS1/EBP/FDPS/LSS/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/FGFR4/STARD4/FDFT1/SQLE/NSDHL/ACLY/SC5D/IL1A/EGR1/G6PD/SRD5A3/APOE/TM7SF2/ERG28/CYP27B1/MVK/HSD17B12/TNF/CYP46A1/BMP2/HSD3B7
GOBP_T_CELL_ACTIVATION 362 0.3972601 1.610977 0.0000375 0.0016082 0.0013212 2641 TREML2/FGL2/DPP4/SOCS1/CDH26/RASGRP1/THY1/CD274/LGALS7B/PTPN22/PDCD1LG2/PRDM1/RSAD2/CD55/CD44/ADAM8/NOD2/RUNX2/BCL11B/IL4I1/PRKCQ/DLL4/EBI3/IDO1/BCL2/IL1A/FZD5/TOX/EGR1/CD47/CD70/GATA3/SLC7A1/HSH2D/CD86/MICA/RELB/ANXA1/CD276/HLA-DOB/TNFSF9/IL18R1/RIPK3/NFKBID/CARD11/CEACAM1/DUSP10/IL23A/ICAM1/ZC3H12A/DUSP3/CD83/ARG2/IL4R/DLG1/ZBTB7B/CCL5/LGALS9/FYN/CCND3/FKBP1B/GSN/SPINK5/FADD/IL1RL2/CD7/MICB/MYH9/RIPK2/IL20RB/PRELID1/ELF4/CD46/TNFRSF13C/MAP3K8/IL15/RAB29/BATF/PRNP/BCL10/DLG5/SCRIB/AP3D1/HLA-DQB2/PAWR/AKT1/MSN/ADAM17/RORA/JMJD6/RUNX1/CD151/CTPS1/CGAS/SRC/PTPN11/IL27RA/BCL3/IL6ST/LGALS3
GOBP_LEUKOCYTE_CELL_CELL_ADHESION 278 0.4173369 1.658762 0.0000398 0.0016906 0.0013889 2887 FGL2/HAS2/DPP4/SOCS1/RASGRP1/SELP/THY1/CD274/LGALS7B/SLC39A8/PTPN22/PDCD1LG2/SELL/CD55/CD44/ADAM8/NOD2/KLF4/STK10/IL4I1/PRKCQ/CERCAM/EBI3/IDO1/IL1A/CD47/CD70/GATA3/SLC7A1/CD86/ANXA1/CD276/HLA-DOB/TNFSF9/NFKBID/CARD11/CEACAM1/DUSP10/IL23A/ICAM1/TNF/ZC3H12A/DUSP3/CD83/ARG2/IL4R/DLG1/PTAFR/TNIP1/ZBTB7B/CCL5/ST3GAL4/LGALS9/FYN/NR4A3/FADD/IL1RL2/IRAK1/RIPK2/IL20RB/CD46/TNFRSF13C/ITGB7/MAP3K8/IL15/ASS1/PRNP/BCL10/DLG5/SCRIB/AP3D1/HLA-DQB2/PAWR/AKT1/MSN/CD177/RELA/RUNX1/SRC/PTPN11/IL27RA/IL6ST/MIA3/LGALS3/FUT4/ALOX5/SYK/OLR1/SKAP1/CSK/CAV1/NFAT5/IGF2
GOBP_ERK1_AND_ERK2_CASCADE 237 0.4341435 1.682148 0.0000420 0.0017657 0.0014506 2603 CCL26/NTRK1/ADRA1A/RASGRP1/ALOX15/TLR4/PTPN22/CCL4/CD44/SPRY4/NOD2/FGFR4/ARHGEF5/ALKAL1/DUSP5/CCL22/NTRK2/CD36/NTRK3/IL1A/FGF2/ARRB2/APOE/EDN1/CAVIN3/GRB10/P2RY1/MFHAS1/S100A7/SOX9/ROR2/CEACAM1/DUSP10/KDR/SEMA7A/ICAM1/TNF/DUSP3/CX3CL1/LIF/DUSP7/DLG1/SPRED2/TNIP1/EPHA2/BMP2/CCL5/LGALS9/SEMA6A/ERRFI1/CARD9/ABCA7/DUSP6/NDRG4/P2RY6/ITGAV/ACTA2/RIPK2/GAREM1/ATF3/GCNT2/CNKSR3/FLCN/GBP1/JUN/TRPV4/MYC/GPER1/GAS6/SRC/PTPN11/CCL20/ARHGAP8/NOD1/EPHA7/PRXL2C
GOBP_REGULATION_OF_VIRAL_PROCESS 134 0.4945707 1.785110 0.0000440 0.0018327 0.0015056 3085 APOBEC3A/CH25H/RSAD2/ISG15/OAS3/ISG20/OASL/OAS1/CXCL8/MX1/IFIT1/BCL2/IFITM1/IFIH1/STOM/BST2/TYRO3/NECTIN2/OAS2/TMPRSS2/LAMP3/VPS37B/IFITM3/ZFP36/TNF/SHFL/TNIP1/IFIT5/CCL5/LGALS9/TRIM14/GSN/AXL/ADAR/STAT1/PLSCR1/TRIM21/N4BP1/EIF2AK2/APOBEC3B/TRIM25/PARP10/ZNFX1/FCN3/TMPRSS4/TRIM5/PDE12/IFI16/LARP1/TBC1D20/HEXIM1/SRPK1/TRIM22/PKN2/VPS4A/RAD23A
GOBP_MITOTIC_METAPHASE_PLATE_CONGRESSION 52 -0.6031529 -1.954348 0.0000445 0.0018386 0.0015105 1478 KIF22/KIF18A/PSRC1/CCNB1/KIFC1/CDT1/CDCA5/NDC80/KIF14/CENPE/NUF2/KIF2C/CEP55
GOBP_MALE_GAMETE_GENERATION 375 -0.3573809 -1.547192 0.0000463 0.0018946 0.0015565 3442 SMARCA2/PRKAG1/SOX30/FIGNL1/ATM/BRCA2/TCP11/ROPN1B/MERTK/PATZ1/SLC22A16/SPATA6/PYGO1/AZIN2/SFMBT1/OAZ3/PACRG/CFAP54/MORN2/RPL39L/BBS2/SPAG8/SPDYA/SPATA6L/NOTCH1/TSNAXIP1/ARMC2/PAIP2/IMMP2L/SPATA24/SYNE1/FOXJ1/HORMAD1/DPCD/SPEF2/LRRK2/TTC21A/MYCBP/ZSCAN2/CFAP58/ROPN1L/NDC1/CFAP69/IFT27/CFAP91/PCSK4/CREB3L4/DRC7/INPP5B/SPAG16/SPINK1/CFAP47/SPA17/TTC12/NPHP1/ERCC1/RFX2/DNAH1/CETN2/IFT81/HSF2/TSPAN8/SIX5/SLC26A8/IQCG/TDRP/RACGAP1/NME5/CCDC136/RSPH1/SPATA32/TCFL5/CFAP44/SPOCD1/HOOK1/IFTAP/TDRD6/CFAP65/TESMIN/GAMT/BBS4/MNS1/HOATZ/CFAP43/ROS1/MCM8/KIF18A/TSGA10/CFAP206/ZCWPW1/HSPA2/CCDC87/PMFBP1/M1AP/SPATA9/BRIP1/HMGB2/SPAG4/PIWIL2/HROB/HSF2BP/TRIP13/GJA1/ELL3/KIT/MEIG1/PTTG1/NEURL1/YBX2/KNL1/E2F1/MGAT4D/MYBL1/OCA2/MYCBPAP/BCL2L10/H1-1/ASF1B/TSSK3/CYP26B1/AR/CATSPERD/NLRP14/DMC1/ZBTB16/CDC25C/ASPM/CNTD1
GOBP_REGULATION_OF_CELL_CELL_ADHESION 345 0.4082131 1.652196 0.0000469 0.0019045 0.0015646 2711 FGL2/EMILIN2/HAS2/DPP4/SOCS1/C1QTNF1/RASGRP1/SELP/THY1/CD274/LGALS7B/PTPN22/PDCD1LG2/MUC21/PLAUR/CD55/CD44/ADAM8/NOD2/KLF4/IL4I1/PRKCQ/EBI3/IDO1/VEGFA/IL1A/FUT3/EPHB3/CD47/CD70/GATA3/SLC7A1/CD86/IL1RN/CD9/ANXA1/CD276/HLA-DOB/TNFSF9/NFKBID/NOTCH4/CARD11/CEACAM1/DUSP10/IL23A/TNF/ZC3H12A/PIEZO1/DUSP3/CD83/CX3CL1/ARG2/IL4R/DLG1/PTAFR/BMP2/ZBTB7B/CCL5/ST3GAL4/LGALS9/FYN/SOX2/NR4A3/SH2B3/FADD/IL1RL2/TJP1/SPINT2/PTPRG/IRAK1/RIPK2/IL20RB/CD46/TENM3/TNFRSF13C/MAP3K8/IL15/GCNT2/ASS1/BMP6/MYO10/PRNP/BCL10/DLG5/SCRIB/AP3D1/HLA-DQB2/PAWR/AKT1/PODXL/EFNA5/TRPV4/UBASH3B/RELA/RUNX1/PDPN/SRC/PTPN11/IL27RA/EPHA7/IL6ST/MIA3/LGALS3/FUT4/ALOX5/SYK
GOBP_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT 125 0.5086509 1.815047 0.0000475 0.0019131 0.0015717 1954 NTRK1/PLA2G3/PRKD1/CNR1/BDNF/ALKAL1/NTRK2/NTRK3/PPP2R5B/TOX/RELN/LRP8/APOE/TWF2/EPHA3/ROR2/CAMK1D/FZD1/LRRC7/CX3CL1/DBN1/RGS2/ATP8A2/FYN/NDEL1/ITGA6/FKBP1B/NDRG4/ARSB/EHD1/ITPKA/TENM3
GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS 90 0.5683081 1.944226 0.0000499 0.0019751 0.0016226 2366 FGL2/SERPINB4/ISG15/PPARG/OAS3/IL4I1/NLRC5/OAS1/SERPINB9/USP18/TYRO3/ARRB2/UFD1/MICA/TRIB1/CEACAM1/DUSP10/AHR/ARG2/PARP14/LGALS9/RNF125/SPINK5/ADAR/MICB/TRIM21/NPLOC4/TNFAIP3/SEC14L1/TRAFD1/HLA-F/STAT2
GOBP_RESPONSE_TO_INTERLEUKIN_1 102 0.5542671 1.936883 0.0000495 0.0019751 0.0016226 2546 CCL26/HAS2/ZBP1/IL1R2/HYAL1/CCL4/SFRP1/CXCL8/CCL22/KLF2/EGR1/CD47/HYAL3/EDN1/IL1RN/ANXA1/IRAK2/HIF1A/SOX9/MYD88/ZC3H12A/CX3CL1/RPS6KA4/MAPK11/CCL5/LGALS9/SNCA/IL1RL2/IRAK1/RIPK2/ST18/GBP1/RORA/MYC/IRAK4/NKX3-1/RELA/SRC/CCL20/UPF1
GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 118 0.5243651 1.853422 0.0000508 0.0019932 0.0016375 1547 CLDN5/GDNF/FOXE3/ZBED2/PAX6/HES5/TRIM16/MAFF/VEGFA/ALOX15B/IL1A/FGF2/GATA3/SFN/XDH/CYP27B1/CDKN1C/BTG1/NOTCH4/MSX2/S1PR3/VCL/SOX9/CEACAM1/ZFP36/TNF/MAFG/ASCL1/YAP1/LIF/SPRED2/PRKCH/CDKN2B/OSR1/ERRFI1
GOBP_STEROL_METABOLIC_PROCESS 116 0.5249047 1.857296 0.0000548 0.0021341 0.0017533 1710 CYP51A1/MVD/HMGCS1/EBP/FDPS/LSS/PCSK9/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/LDLR/FDFT1/NPC1/SQLE/NSDHL/ACLY/SC5D/NFE2L1/LCAT/G6PD/APOE/TM7SF2/ERG28/MVK/SCARB1/APOL2/CYP46A1/SREBF2/APOBR/CYP2C9/APOL1/ACADL/GBA2
GOBP_IMPORT_INTO_CELL 164 0.4806486 1.775566 0.0000576 0.0022172 0.0018215 2338 SLC18A2/TRPV6/GDNF/ATP12A/SLC9A3/SLC5A1/SLC39A8/SLC7A11/KCNJ16/LRRC8D/SYNGR3/SLC6A14/CD36/SLC3A2/SLC29A2/SLC12A2/SLC7A5/LRRC8A/SLC7A1/HCN2/SLC1A5/SCNN1D/SLC5A3/SLC36A1/ACSL1/SLC1A4/TRPV3/TNF/SLC27A4/SLC38A1/IRS2/LRRC8C/RGS2/DLG1/TRPM4/SLC15A3/EPRS1/THBS1/FYN/SLC12A4/ATP1B1/SLC9A1/SLC6A9/SLC9A4/NOS1/SNCA/SLC8A1/SLC39A4/ACTB/SLC39A14/PRNP/TFR2/ATP1A1/GRM1/SLC6A11/AKT1/SLC29A4/TRPV4
GOBP_REGULATION_OF_GTPASE_ACTIVITY 304 0.4087300 1.636119 0.0000579 0.0022172 0.0018215 3004 CCL26/NTRK1/RASGRP1/THY1/FZD10/RGS7/RTN4R/CCL4/SFRP1/ARHGEF5/CPEB2/CCL22/NTRK2/NTRK3/ADPRH/AMOT/NEDD9/ARHGAP11B/EPHB3/GRHL3/RAP1GAP/ARRB2/RGS16/MET/RIC1/FGD2/DOCK11/BIN1/GMIP/EPHA3/ASAP3/PLXNA3/ADAP2/GPSM1/SNX9/SLC27A4/CX3CL1/CAV2/FGD3/EPHA2/ARHGAP27/CCL5/RHOG/NDEL1/ITGA6/TBC1D22A/FGD6/ADAP1/RASA2/SIPA1L2/RAP1GAP2/TBC1D14/ARHGEF10/STMN3/EVI5L/RASIP1/CHN1/FLCN/PIP5K1A/SCRIB/TBC1D10A/S100A10/SH3BP1/EFNA5/NGEF/PICALM/CCPG1/CCL20/RAPGEF4/MAPRE2/BCR/TBC1D4/TIAM1/TBC1D9/RGP1/VAV2/TBC1D20/TIAM2/RAP1A/DOCK7/TBC1D16/CRK/SIPA1L1/FERMT2/DOCK6/SMCR8
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS 197 -0.4141574 -1.665641 0.0000596 0.0022615 0.0018579 3038 CHEK2/SLF1/GPSM2/AURKA/RAD51B/RGCC/KIF23/SMPD3/NANOGP8/DYRK3/CENPJ/DRD2/EZH2/MAPK15/SASS6/CEP120/CCN2/ATAD5/PBX1/RACGAP1/MAP10/RRM1/ESPL1/STIL/PRKCE/CDC7/MTBP/INSR/ADAMTS1/HSPA2/WNT5A/CDC25A/STOX1/FBXO5/ANAPC4/CCNB1/PIWIL2/EPGN/RAD51AP1/CDC14A/SPAG5/KIF20B/E2F7/CIT/CDT1/CDCA5/NDC80/KIF14/MAD2L1/PLK4/CDK1/RRM2/DTL/DLGAP5/CDC25C/UBE2C
GOBP_CENTROMERE_COMPLEX_ASSEMBLY 30 -0.6961618 -2.025210 0.0000624 0.0023479 0.0019289 2253 NASP/MIS18A/CENPH/CENPS/HELLS/CENPK/CENPP/CENPF/CENPW/CENPE/DLGAP5/OIP5/HJURP
GOBP_NEGATIVE_REGULATION_OF_CELL_ACTIVATION 139 0.4871617 1.769780 0.0000643 0.0024010 0.0019725 2372 FGL2/SOCS1/C1QTNF1/IL13RA2/CD274/LGALS7B/PTPN22/PDCD1LG2/CNR1/SFRP1/LDLR/IL4I1/IL31RA/IDO1/TYRO3/APOE/CD86/MICA/CD9/ANXA1/THBD/CEACAM1/ZC3H12A/DUSP3/CX3CL1/SYT11/HMOX1/ARG2/IL4R/DLG1/ZBTB7B/LGALS9/AXL/SH2B3/IL20RB/TNFAIP3/PRNP/DLG5/SCRIB/PAWR/HLA-F/UBASH3B/GPER1
GOBP_CHROMOSOME_LOCALIZATION 79 -0.5301065 -1.855338 0.0000649 0.0024056 0.0019763 1478 KIF22/KIF18A/PSRC1/FMN2/CCNB1/KIFC1/SPAG5/CDT1/CDCA5/NDC80/KIF14/CENPF/CENPE/NUF2/KIF2C/CEP55/DLGAP5
GOBP_REGULATION_OF_PLATELET_ACTIVATION 33 0.7088682 1.995669 0.0000708 0.0026011 0.0021369 2711 EMILIN2/C1QTNF1/SELP/TLR4/PRKCQ/APOE/PLA2G4A/CD9/THBD/CEACAM1/SH2B3/TEC/UBASH3B/PDPN/IL6ST/SYK
GOBP_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY 48 0.6381020 1.923864 0.0000763 0.0027578 0.0022656 1835 SH2D1B/RASGRP1/SERPINB4/ULBP1/PVR/RAET1G/SERPINB9/UNC13D/ARRB2/MICA/RAET1E/NECTIN2/ULBP2/CEACAM1/CEBPG/LGALS9/RNF19B/TUBB/ULBP3
GOBP_METAPHASE_PLATE_CONGRESSION 64 -0.5601793 -1.887646 0.0000759 0.0027578 0.0022656 1478 KIF22/KIF18A/PSRC1/CCNB1/KIFC1/SPAG5/CDT1/CDCA5/NDC80/KIF14/CENPF/CENPE/NUF2/KIF2C/CEP55
GOBP_GLYCEROLIPID_METABOLIC_PROCESS 322 0.3975650 1.602154 0.0000768 0.0027578 0.0022656 2787 CISH/PLA2G3/SOCS1/PNPLA3/APOC1/ALOX15/AADAC/LIPG/PCSK9/INSIG1/PCK2/LDLR/LPIN1/MFSD2A/PLA2G4C/ABHD4/ENPP6/SOCS2/PNPLA1/PLAAT1/LCAT/LIPH/FGF2/CPT1A/PLA2G7/APOE/PLA2G4A/GPCPD1/ACSL1/SCARB1/SERAC1/GPAT3/LPCAT4/FAR1/SOCS3/PISD/PLCB3/APOBR/ABCA3/TMEM150A/PIGW/SERINC5/PTPMT1/SELENOI/PLSCR1/ITPKA/DGKI/GPAT4/PGAP4/PLCE1/PIP4K2A/DGKQ/SORL1/TAFAZZIN/ACP6/GDPD3/CAPN2/PIP5K1A/INPP1/MBOAT1/PIK3C2B/PLD2/MTMR12/INPPL1/DGKA/PTDSS1/PIP4P1/PTPN11/LPIN2/PITPNM2/ITPKC/CYP2E1/TTC7A/LPIN3/ABHD3/OSBPL5/ACSL3
GOBP_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY 258 0.4179685 1.639558 0.0000835 0.0029761 0.0024450 2655 CST1/FETUB/APOC1/SERPINB4/FZD10/SERPINB2/SERPINB10/HMSD/SERPINC1/SERPINB13/PLAUR/SERPINB12/CD44/KLF4/LPIN1/NR4A1/CPEB2/AMOT/HDAC9/VEGFA/CSTA/SERPINB9/IFI6/BST2/ARRB2/SFN/UBE2Z/SERPINB8/SERPINB7/ANXA1/ANOS1/PI3/TIMP2/BIN1/GMIP/LAMP3/TFPI2/ANXA8/PTGS2/ITIH2/GPSM1/TNF/SERPINB6/SLC27A4/SERPINB11/CSTB/RGS2/THBS1/SERPINB1/FKBP1B/SERPINB3/SPINK5/NOS1/SERPINH1/SNCA/SPINT2/ANXA8L1/A2ML1/SORL1/MASTL/SLC39A14/TIMP1/FURIN/PRNP/DHCR24/MICAL1/AKT1/GAS6/PICALM/CHP1/USP14/RFFL/SRC/BIRC3/PAK2/LGALS3/DNAJB6
GOBP_NEGATIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE 39 -0.6390428 -1.950171 0.0000891 0.0031283 0.0025701 918 FBXO5/CCNB1/TRIP13/TTK/CDT1/NDC80/MAD2L1/CENPF/PLK1/BUB1/BUB1B
GOBP_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE 61 0.6111885 1.949366 0.0000887 0.0031283 0.0025701 1591 NOS2/PLA2G3/IL1R2/NCF1/TLR4/NOD2/GBP5/CD36/ADCY7/TICAM1/HIF1A/DUSP10/MYD88/TNF/ZC3H12A/IL4R/APPL2/CARD9
GOBP_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE 52 -0.5873256 -1.903064 0.0000942 0.0032835 0.0026976 2458 HORMAD1/MRE11/SMC4/NDC1/SMC2/ZCWPW1/PSMC3IP/BRIP1/STAG3/TRIP13/SGO2/NCAPH/CCNE2/SGO1/BUB1/DMC1/BUB1B
GOBP_REGULATION_OF_MEIOTIC_CELL_CYCLE 35 -0.6512333 -1.947722 0.0000974 0.0033694 0.0027681 1301 INSR/WNT5A/CDC25A/FBXO5/PIWIL2/TRIP13/RAD51AP1/TTK/FBXO43/CDC20/CDC25C/ASPM/CNTD1
GOBP_HORMONE_TRANSPORT 203 0.4472822 1.697675 0.0001018 0.0034965 0.0028725 2614 NOS2/ANO1/PLA2G3/TRPV6/C1QTNF1/ADCY5/SLC9B2/CNR1/SFRP1/PCK2/PPARG/SLCO4A1/SLCO1B1/FOXD1/SLC7A5/LRRC8A/GATA3/CPT1A/EDN1/IL1RN/DOC2B/ANXA1/RAB11FIP1/P2RY1/STX1A/HIF1A/BRSK2/RAB8B/TNF/NIBAN2/IRS2/LIF/GPR27/TRPM4/CCL5/CCN3/FKBP1B/ACSL4/SLC8B1/AACS/VSNL1/LTBP4/GABBR1/BMP6/PIM3/MCU/EIPR1/TFR2/SPP1/EFNA5/RAB11FIP5/TRPV4/NKX3-1/GPER1/STX4/PTPN11/RAPGEF4/ACVR1C/PPARD
GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY 195 0.4532010 1.706706 0.0001131 0.0038329 0.0031489 2149 SH2D1B/RASGRP1/IL13RA2/C8B/SERPINB4/CTSC/RSAD2/CD55/NOD2/IL4I1/ULBP1/PVR/RAET1G/SERPINB9/FZD5/UNC13D/CLCF1/CD70/IRF7/GATA3/ARRB2/TNFSF13/MICA/RAET1E/NECTIN2/ULBP2/HLA-DOB/IL18R1/RIPK3/ARID5A/CEACAM1/IL23A/MYD88/ICAM1/TNF/CEBPG/AHR/IL4R/TRPM4/LGALS9/CARD9/RNF19B/TUBB/FADD/ULBP3/IL20RB/C1S/RNF8/CD46/SHLD2/BATF/BCL10
GOBP_REGULATION_OF_SECRETION 429 0.3676353 1.525335 0.0001133 0.0038329 0.0031489 2718 NOS2/ANO1/ADRA1A/PLA2G3/ADRA2C/TRPV6/GDNF/C1QTNF1/IL13RA2/CYP51A1/TLR4/ACHE/ADCY5/SLC9B2/CNR1/SGK1/HMGCR/SFRP1/RSAD2/PCK2/ADAM8/PPARG/ACE/KCNMB4/IL1A/UNC13D/SLC12A2/CLASP1/LRRC8A/CPT1A/HYAL3/APOE/ADAM9/EDN1/TTN/PLA2G4A/DOC2B/ANXA1/RAB11FIP1/P2RY1/RIC1/SYT17/STX1A/OAS2/LLGL2/HIF1A/BRSK2/RAB8B/CEACAM1/TNF/RIMS3/KCNA2/GAB2/IRS2/SYT11/HMOX1/LIF/GPR27/IL4R/PTAFR/TRPM4/BMP2/CCL5/SYT1/LGALS9/CCN3/FKBP1B/RAB15/ITGAM/PRKCG/ACSL4/P2RX4/TPCN2/SNCA/SLC8B1/ATP13A2/AACS/RAB9A/CHMP6/VSNL1/GABBR1/BMP6/PIM3/MCU/EIPR1/TFR2/MICAL1/SPP1/STXBP5/EFNA5/HLA-F/RAB11FIP5/NKX3-1/GPER1/CD177/DRD1/PNKD/STX4/PTPN11/RAPGEF4/RHBDF2/GIPC1/ACVR1C/PPARD/STXBP2/BCR/ALOX5/RALA/RHBDD3/SYK/MYO18A
GOBP_DNA_REPLICATION_INDEPENDENT_CHROMATIN_ORGANIZATION 32 -0.6663925 -1.954484 0.0001177 0.0039542 0.0032486 4032 UBN2/RBBP4/ITGB3BP/H3-3A/H4C5/H4C12/HAT1/H4C6/H4C3/H4C2/NASP/MIS18A/H4C4/H4C1/H4C13/H4C9/CENPP/CENPW/ASF1B/OIP5/HJURP
GOBP_INTERFERON_GAMMA_PRODUCTION 77 0.5705778 1.904370 0.0001308 0.0043616 0.0035833 1872 RASGRP1/CD274/LGALS7B/TLR4/PTPN22/PDCD1LG2/IL1RL1/ISG15/IL12RB2/NOD2/EBI3/DDIT3/FZD5/CD47/SLC7A5/GATA3/CD276/IL18R1/RIPK3/ARID5A/IL23A/TNF/CEBPG/ZC3H12A/LGALS9/AXL/PDE4B/FADD/RIPK2/IL20RB
GOBP_MONOCYTE_CHEMOTAXIS 39 0.6719330 1.965495 0.0001363 0.0045140 0.0037085 1561 CCL26/PTPRO/CXCL10/CCL4/SLIT2/CCL22/FLT1/PLA2G7/ANXA1/S100A7/CX3CL1/CCL5/CCN3/GREM1
GOBP_PYRIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS 33 0.6947392 1.955892 0.0001527 0.0050220 0.0041258 2035 IDO2/PSAT1/SLC5A8/NNMT/HAAO/ALPL/IDO1/PARP9/NUDT17/QPRT/NAMPT/KYNU/NADK/PARP10/PDXK
GOBP_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 80 -0.5125528 -1.799874 0.0001639 0.0053519 0.0043968 1930 PBX1/RRM1/ESPL1/STIL/CDC7/MTBP/ADAMTS1/HSPA2/CDC25A/STOX1/FBXO5/ANAPC4/CCNB1/CDT1/CDCA5/CDK1/RRM2/DTL/DLGAP5/CDC25C/UBE2C
GOBP_CELL_CHEMOTAXIS 213 0.4292488 1.638277 0.0001659 0.0053804 0.0044203 1831 CCL26/DPP4/TNFAIP6/PTPRO/DEFB4A/CXCL10/PRKD1/HBEGF/CCL4/CH25H/CXCL11/ADAM8/NOD2/CXCL9/ARHGEF5/HRH1/NR4A1/SLIT2/CXCL8/CCL22/PRKCQ/FLT1/CXCL16/VEGFA/SLC12A2/FGF2/DAPK2/SMOC2/PLA2G7/ARRB2/EDN1/MET/ANXA1/CCR3/S100A7/CXCL1/IL23A/KDR/CAMK1D/CX3CL1/ITGA9/TRPM4/EPHA2/PLEKHG5/CCL5/HSD3B7/LGALS9/THBS1/BCAR1/RHOG/CXCL2/CCN3/GREM1/LOX/MMP28/P2RX4/OXSR1/PDE4B/CXCL6/RAC1/SLC8B1
GOBP_RESPONSE_TO_TUMOR_NECROSIS_FACTOR 192 0.4442700 1.673043 0.0001674 0.0053902 0.0044283 3063 CCL26/HAS2/HYAL1/CCL4/SFRP1/PCK2/CXCL8/CCL22/UBD/AIM2/CXCL16/KLF2/GPS2/CD70/GATA3/HYAL3/ADAM9/EDN1/NFKBIA/PTGS2/ZFP36/TNF/ZC3H12A/FAS/KRT18/CX3CL1/SPHK1/GCH1/CCL5/THBS1/TNFRSF19/TNFRSF25/STAT1/TRAF5/CDIP1/TNFAIP3/TNFRSF13C/ASS1/ST18/GBP1/AKT1/YBX3/TMSB4X/ADAM17/RORA/NKX3-1/GPER1/GAS6/RELA/RFFL/CYLD/CCL20/CLDN1/MAP4K3/BIRC3/SYK/SMPD1/TRAF3IP2/ACTN4/CCDC3/PELI3/ARHGEF2/NKIRAS2
GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION 224 0.4311466 1.659480 0.0001696 0.0054229 0.0044552 2887 EMILIN2/HAS2/DPP4/SOCS1/RASGRP1/SELP/THY1/CD274/PTPN22/PDCD1LG2/PLAUR/CD55/CD44/ADAM8/NOD2/IL4I1/PRKCQ/EBI3/IL1A/FUT3/CD47/CD70/GATA3/SLC7A1/CD86/ANXA1/CD276/HLA-DOB/TNFSF9/NFKBID/CARD11/DUSP10/IL23A/TNF/PIEZO1/CD83/CX3CL1/IL4R/PTAFR/ZBTB7B/CCL5/ST3GAL4/LGALS9/FYN/SOX2/NR4A3/FADD/IL1RL2/TJP1/IRAK1/RIPK2/CD46/TNFRSF13C/MAP3K8/IL15/GCNT2/MYO10/BCL10/AP3D1/HLA-DQB2/AKT1/PODXL/RELA/RUNX1/PDPN/SRC/PTPN11/IL27RA/IL6ST/FUT4/ALOX5/SYK/SKAP1/CSK/CAV1/NFAT5/IGF2
GOBP_HYALURONAN_BIOSYNTHETIC_PROCESS 13 0.8529732 1.947950 0.0001743 0.0055365 0.0045485 307 HAS2/HYAL1/CEMIP/HAS3
GOBP_PROCESS_UTILIZING_AUTOPHAGIC_MECHANISM 493 0.3564201 1.493651 0.0002025 0.0063886 0.0052485 4871 ADRA1A/PTPN22/TRIB3/PRKD1/ATP6V1C2/NOD2/ATP6V0D2/NPC1/UCHL1/ADPRH/RAB24/BCL2/PLK3/DDIT3/DEPP1/FZD5/SESN2/DAPK2/HSPB8/EEF1A2/TICAM1/MET/HK2/WASHC1/LAMP3/HIF1A/VPS37B/MAP1LC3B2/GPSM1/KDR/VPS37D/ZC3H12A/ATP6V0A2/RUBCN/VMP1/SYT11/RNF213/HMOX1/OPTN/SREBF2/TRIM14/RRAGC/RRAGD/TPCN2/SNCA/CAMKK2/ARSB/RAB43/TRIM21/TBC1D14/ATP13A2/RIPK2/CTTN/PIP4K2A/HDAC6/ATP6V1E2/CHMP6/TAFAZZIN/RASIP1/FLCN/ACER2/SQSTM1/DEPDC5/MTCL1/CHMP7/DAPK3/AKT1/BOK/ATG4D/TECPR2/AUP1/NEDD4/EIF4G1/FOXK1/TRIM5/SRC/MUL1/PLAA/CPTP/EPM2A/ATG2A/TMEM41B/MCOLN1/NOD1/TIGAR/NRBP2/CALCOCO2/DDRGK1/RGS19/IFI16/LARP1/SIRT2/STX12/HAX1/IKBKG/FOXK2/MFN2/TRIM22/EVA1A/SMCR8/PIP4K2C/ATG101/VPS4A/RPTOR/VPS4B/TSC1/HTT/CHMP1B/PACS2/ILRUN/MAP1LC3B/PLK2/ATG9A/ATG7/SNF8/TP53/PLEKHM1/RAB8A/PGAM5/VPS37A/TGFBRAP1/RNF185/TOLLIP/GABARAPL1/ATP6V1H/ITGB4/ARL8B/SPTLC2/VTI1A/ERN1/RETREG3/EXOC8/MAP1S/PHF23/SNX30/UBQLN1/CDK5R1/CDC37/MTOR/TAB3/GNAI3/SLC25A46/BCL2L11/PIK3CB/RAB7A/RMC1/SLC25A5/RNF166/TP53INP2/TSPO/TRIM65/ATG4A/TBC1D25/VCP/MVB12A/RHEB/ATG13/UFM1/DRAM1/VPS29/MAPK3/ATP6V0A1/USP36/TFEB/RAB5A/PSEN1/ATP6V0B/ATP6V1B2/ATP6V0D1/ZFYVE1/RALB/VPS26A/TAB2/SH3BP4/NUPR1/UBXN2A/CAPN1/VIPAS39/FBXL2/SMG1/TECPR1/TLK2/MCL1/TMEM208/ATG16L1/CSNK2A2/ACBD5/VPS33B/UBQLN4/GSK3A/RNF41/RAB3GAP2/DNM1L/CHMP1A/ATP6V0E1/PIKFYVE/MARK2/STAM/CHMP3/SPTLC1/GSK3B/PARL/KEAP1/GOLGA2/STUB1/DAP/SBF2/ELAPOR1/SEC16A/BAD
GOBP_CELLULAR_RESPONSE_TO_LIPID 432 0.3558567 1.473720 0.0002041 0.0063959 0.0052545 2731 NOS2/FZD10/CD274/BRINP1/TLR4/PTPN22/PDCD1LG2/ADCY5/CXCL10/SGK1/INSIG1/SFRP1/PCK2/CD55/CXCL11/GJB2/PPARGC1B/IL36G/NOD2/CXCL9/TNIP3/LBH/LDLR/CMPK2/ACE/NPC1/CXCL8/CD36/NTRK3/IL36A/IL1A/LRP8/CPT1A/GJB3/TICAM1/CD86/ADAM9/EDN1/TWF2/CYP27B1/ANXA1/HCK/LY96/KLF9/TRIB1/IRAK2/ARID5A/SCARB1/NFKBIA/EPHA3/MSX2/SOX9/CXCL1/ZFP36/MYD88/TNF/ZC3H12A/AHR/CX3CL1/YAP1/ID3/PTAFR/TNIP1/WNT6/CCL5/OSR1/CXCL2/ERRFI1/NR4A3/PIM1/AXL/PDE4B/CXCL6/IRAK1/VDR/RIPK2/TNFAIP3/HDAC6/IL15/ASS1/BMP6/SBNO2/NFKBIB/BCL10/PTK6/CAPN2/SPP1/ATP1A1/AKT1/MSN/EFNA5/RORA/MYC/SELENOS/NKX3-1/GPER1/PF4V1/NEDD4/RELA/TRIM5/GFI1/SRC/PLAA/CLDN1/UPF1/CSF2/PPARD/BCR/DDRGK1/SYK/DAG1/TEAD2
GOBP_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY 169 0.4491309 1.667205 0.0002086 0.0064933 0.0053345 2655 CST1/FETUB/SERPINB4/SERPINB2/SERPINB10/HMSD/SERPINC1/SERPINB13/PLAUR/SERPINB12/CD44/KLF4/NR4A1/VEGFA/CSTA/SERPINB9/IFI6/BST2/ARRB2/SFN/UBE2Z/SERPINB8/SERPINB7/ANOS1/PI3/TIMP2/BIN1/LAMP3/TFPI2/ANXA8/PTGS2/ITIH2/TNF/SERPINB6/SERPINB11/CSTB/THBS1/SERPINB1/SERPINB3/SPINK5/SERPINH1/SNCA/SPINT2/ANXA8L1/A2ML1/SORL1/TIMP1/FURIN/PRNP/DHCR24/MICAL1/AKT1/GAS6/PICALM/USP14/RFFL/SRC/BIRC3/PAK2/DNAJB6
GOBP_TRIGLYCERIDE_METABOLIC_PROCESS 69 0.5623644 1.841004 0.0002164 0.0066927 0.0054984 1094 PNPLA3/APOC1/AADAC/LIPG/PCSK9/INSIG1/PCK2/LDLR/LPIN1/MFSD2A/PNPLA1/LIPH/CPT1A/APOE/ACSL1/SCARB1/GPAT3
GOBP_HYALURONAN_METABOLIC_PROCESS 23 0.7364559 1.931168 0.0002201 0.0067614 0.0055548 1159 HAS2/TNFAIP6/HYAL1/CEMIP/CD44/HAS3/FGF2/HYAL3/ITIH2
GOBP_CHLORIDE_TRANSPORT 74 0.5568810 1.848768 0.0002249 0.0068617 0.0056372 1688 ANO1/GABRA4/SLC26A4/CA2/SLC26A9/SLC5A1/TTYH2/ANO2/CLIC2/ANO4/CLIC3/SLC12A2/LRRC8A/CLIC4/SLC26A6/ANO8/ATP8B1/CLDN4/PTAFR/CLCN6/ANO7/SLC12A4/APOL1/P2RY6
GOBP_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS 69 0.5608528 1.836055 0.0002291 0.0069446 0.0057053 1949 FGL2/IL13RA2/SERPINB4/CD55/NOD2/IL4I1/SERPINB9/CD47/BST2/ARRB2/MICA/ANXA1/CEACAM1/DUSP10/TNF/ZC3H12A/AHR/HMOX1/IL4R/ZBTB7B/LGALS9/SPINK5/IL20RB/CD46
GOBP_HOMOLOGOUS_CHROMOSOME_SEGREGATION 43 -0.5890669 -1.827631 0.0002327 0.0069643 0.0057214 2458 HORMAD1/MRE11/NDC1/ESPL1/ZCWPW1/PSMC3IP/BRIP1/FMN2/STAG3/TRIP13/PTTG1/SGO2/CCNE2/PLK1/SGO1/DMC1
GOBP_SIGNAL_RELEASE 321 0.3921017 1.577528 0.0002312 0.0069643 0.0057214 2629 NOS2/ANO1/ADRA1A/PLA2G3/ADRA2C/TRPV6/GDNF/C1QTNF1/SNPH/ADCY5/SLC9B2/CNR1/SFRP1/PCK2/PPARG/FOXD1/NR4A1/UNC13A/KCNMB4/ERC2/IL1A/LRRC8A/GATA3/CPT1A/EDN1/IL1RN/PLA2G4A/DOC2B/ANXA1/RAB11FIP1/P2RY1/SYT17/STX1A/STX3/SYN2/HIF1A/BRSK2/RAB8B/PPFIA3/TNF/RIMS3/NIBAN2/KCNA2/IRS2/SYT11/LIF/GPR27/TRPM4/BRSK1/CCL5/SYT1/CCN3/FKBP1B/PRKCG/ACSL4/P2RX4/SNCA/SLC8B1/AACS/VSNL1/LTBP4/GABBR1/BMP6/PIM3/MCU/EIPR1/TFR2/SCRIB/SPP1/STXBP5/EFNA5/RAB11FIP5/TRPV4/NKX3-1/GPER1/DRD1/PNKD/STX4/PTPN11/RAPGEF4/GIPC1/ACVR1C/PPARD/STXBP2
GOBP_CELLULAR_AMINO_ACID_METABOLIC_PROCESS 238 0.4177512 1.622315 0.0002390 0.0071076 0.0058392 1183 NOS2/IDO2/CBS/HPDL/SLC39A8/WARS1/PSAT1/SLC7A11/TAT/GARS1/KYAT1/ASNS/HAAO/ASPG/IL4I1/BCAT1/PYCR1/PHGDH/IDO1/MARS1/GPT2/ARHGAP11B/YARS1/DPYD/AARS1/TARS1/GOT1/ATF4/CTH/IARS1/SHMT2/GGT5/GFPT2/HAL/SARS1
GOBP_CILIUM_OR_FLAGELLUM_DEPENDENT_CELL_MOTILITY 104 -0.4635941 -1.702819 0.0002409 0.0071191 0.0058486 3467 CFAP251/DNAI3/CFAP20/ROPN1B/SLC22A16/ENO4/TEKT3/DNAAF2/TEKT5/RSPH4A/CCDC39/CFAP54/DNAI1/BBS2/ARMC2/CFAP52/DPCD/SPEF2/CCDC65/TTC21A/RSPH9/GAS2L2/DNAH7/CFAP58/ROPN1L/TEKT2/CFAP69/DRC7/INPP5B/SPAG16/CFAP47/TTC12/EFHC2/DNAH1/SLC26A8/IQCG/CFAP44/EFHC1/RFX3/CFAP65/PLTP/DNAH3/TEKT1/DNAH6/BBS4/MNS1/HOATZ/TCTE1/CFAP43/CFAP45/CFAP206/TEKT4/DNAH2/TTLL6/DNAH5/DNAAF6/MEIG1/NEURL1/CATSPERD/EPPIN
GOBP_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY 167 0.4575906 1.695723 0.0002441 0.0071668 0.0058878 1268 CCL26/ALOX15/MMP1/TLR4/TRABD2A/WARS1/ISG15/CDC42EP5/MAP1B/GBP5/ARHGEF5/CD36/PPP2R5B/VEGFA/CLASP1/CDC42EP1/MET/HCK/BAK1/BIN1/BIK/CAPG/OCLN/MYD88/TNF/SNX9/PIEZO1
GOBP_RESPONSE_TO_EXTRACELLULAR_STIMULUS 367 0.3747291 1.519100 0.0002471 0.0072113 0.0059244 2822 NTRK1/CBS/FOXA3/POSTN/CXCL10/PRKD1/STC2/LIPG/PCSK9/CNR1/SFRP1/PCK2/PPARG/MAP1B/KL/NOD2/LRAT/NUAK1/FADS1/LDLR/SGIP1/ASNS/SLC25A25/ACE/MFSD2A/ALPL/GDF15/FOS/MARS1/BCL2/IL1A/DDIT3/SESN2/G6PD/CPT1A/APOE/PMAIP1/ATF4/CYP27B1/ACSL1/KIF26A/BRSK2/FOSL1/PTGS2/MAP1LC3B2/ZFP36/TNF/ZC3H12A/FAS/SLC27A4/HMOX1/RIPOR1/ASCL1/APPL2/BRSK1/SREBF2/CDKN2B/NOCT/RRAGC/FKBP1B/PRKCG/PIM1/RRAGD/AXL/ARSB/STAT1/SLC8A1/EIF2AK2/VDR/KYNU/SLC39A4/UPP1/TRIM25/ATF3/SORL1/IL15/ASS1/BCL10/FLCN/CDKN1A/DEPDC5/NDOR1/SPP1/AKT1/TRPV4/GAS6/GAS2L1/EIF4G1/FOXK1/PLEC/SRC/ACVR1C/PPARD/GPT/IFI16/PPARGC1A/LARP1/CHSY1/KPTN/SIRT2/EIF2AK3/MTHFR
GOBP_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE 54 0.6022003 1.867929 0.0002515 0.0072926 0.0059912 4053 SERPINB4/ISG15/PPARG/OAS3/NLRC5/OAS1/SERPINB9/USP18/TYRO3/ARRB2/MICA/CEACAM1/DUSP10/PARP14/LGALS9/ADAR/TRIM21/TNFAIP3/TRAFD1/HLA-F/STAT2/MUL1/IFI16/CRK/DHX58/HLA-G/NMI/HLA-A/TTLL12/HLA-B/HLA-E/FAM3A/CACTIN/YTHDF3
GOBP_ANION_TRANSMEMBRANE_TRANSPORT 184 0.4433257 1.666059 0.0002550 0.0073501 0.0060385 2163 ANO1/GABRA4/SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC5A1/SLC39A8/SLC24A3/SLC5A8/SLC7A11/ANO2/LRRC8D/CLIC2/ANO4/SLC3A2/SLC12A2/SLC7A5/LRRC8A/SLC7A1/SLC1A5/SLC4A9/TCAF2/LRRC8B/SLC26A6/SLC26A11/SLC1A4/TNF/SLC4A3/SLC25A1/LRRC8C/RGS2/PTAFR/CLCN6/SLC25A32/SLC5A12/ANO7/SLC25A3/SLC12A4/SLC38A7/SLC16A7/APOL1/SLC9A1/SLC6A9/SLC9A4/VDAC2/SLC66A1/PRAF2/ANO9/MFSD12/SLC16A3/SLC35D2/SLC25A22/PRNP/SLC35B4
GOBP_KINETOCHORE_ORGANIZATION 22 -0.7293591 -2.001199 0.0002615 0.0074905 0.0061538 2332 SMC4/SMC2/CENPH/CENPS/CENPK/CDT1/NDC80/CENPF/CENPW/CENPE/NUF2/DLGAP5
GOBP_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS 476 0.3566468 1.491240 0.0002652 0.0075487 0.0062016 3443 NOS2/IDO2/APOBEC3A/MVD/HMGCS1/SLC2A6/ADCY5/ELOVL6/SLC5A8/HKDC1/ACSS2/HMGCR/UAP1/NNMT/CRMP1/GARS1/HAAO/ME1/ADCY4/PDE9A/CMPK2/ELOVL5/PDE8B/ACLY/ALDOB/PDE10A/IDO1/ACOT1/ANTKMT/ADCY7/GUCY2C/DPYD/PARP9/FBP1/ELOVL7/HK2/GALT/XDH/MVK/PRTFDC1/ENPP1/HSD17B12/SHMT2/ACSL1/NUDT17/GFPT2/GNE/ALDOC/QPRT/PANK3/HIF1A/CARD11/FAR1/MLXIPL/PFKP/AMD1/ACOT7/SLC25A1/MAGI3/HK1/DLG1/NAMPT/EPHA2/UAP1L1/UCKL1/ELOVL1/ACSL4/DPYSL2/NOS1/ENTPD2/OGDH/ELOVL4/UXS1/SNCA/GNPNAT1/PDE4B/GMPR/ACACA/NUDT8/TYMP/APOBEC3B/ADCY10/KYNU/UPP1/GPAT4/NADK/VPS9D1/GALK1/REXO2/PARP10/TAFAZZIN/PMM2/ENTPD5/FLCN/ENO1/ATP5MC1/TJP2/PDHA1/TMSB4X/RORA/MYC/FOXK1/ATP5F1D/PTHLH/CTPS1/ACOT9/TIGAR/PRXL2C/NT5C2/AMDHD2/ENTPD6/DLST/NAPRT/PPARGC1A/ACSL3/HACD1/FLAD1/PFKFB2/FOXK2/GMDS/UGP2/NUDT16/SIRT6/DCTD/GFUS/NPR2/ADPGK/GFPT1/DCK/GPI/GIT1/GLRX/ATP5MC3/GUK1/NCOR1/PMVK/PDE4D/PANK4/SLC26A2/SLC25A16/ADSS2/CNP/ICMT
GOBP_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS 139 0.4657185 1.691880 0.0002760 0.0078107 0.0064168 3063 SOCS1/ZBP1/IL1R2/TLR4/ISG15/PPARG/OAS3/KLF4/NLRC5/OAS1/SLIT2/IFIH1/GPS2/USP18/IRF7/EDN1/PARP9/IL1RN/PXDN/IRAK2/HIF1A/SPHK1/PARP14/CCL5/AXL/SH2B3/ADAR/FADD/IRAK1/RIPK2/TNFAIP3/ADAM17/STAT2/GAS6/GFI1/RFFL/CYLD/PTPN11/MUL1/SYK/PALM3/CAV1/IKBKE/CCDC3/PELI3/NKIRAS2
GOBP_EPIDERMAL_CELL_DIFFERENTIATION 151 0.4675141 1.711478 0.0002779 0.0078176 0.0064225 1689 SPRR2E/SPRR3/SPRR2F/SPRR2A/KRT16/TMC1/SPRR1A/ZBED2/KLF4/GRXCR2/PAX6/SPRR2D/BCL11B/EREG/FA2H/HES5/TRIM16/MAFF/ALOX15B/CSTA/IL1A/SFN/PLS1/ADAM9/CLIC4/CYP27B1/ANXA1/OVOL1/FOSL2/LCE1E/S100A7/MSX2/ZFP36/MAFG/CDH3/YAP1/EPHA2/PRKCH/ERRFI1/IRF6/SPINK5
GOBP_RESPONSE_TO_CHEMOKINE 53 0.6066444 1.881416 0.0002853 0.0079098 0.0064983 1780 CCL26/CXCL10/CCL4/CXCL11/CXCL9/SLIT2/CXCL8/CCL22/SLC12A2/EDN1/CCR3/HIF1A/CXCL1/ZC3H12A/CX3CL1/CCL5/CXCL2/LOX/SH2B3/OXSR1/CXCL6
GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION 163 0.4542208 1.676452 0.0002863 0.0079098 0.0064983 2722 PLA2G3/CCN4/TNFAIP6/TLR4/SLC9B2/BATF3/SFRP1/MT1G/PPARGC1B/PPARG/BATF2/IL31RA/UBD/FOS/VEGFA/FASN/IRF7/GATA3/RELB/KITLG/TRIB1/ROR2/CEACAM1/ITGB8/IL23A/TNF/GAB2/LIF/EPHA2/LGALS9/TFE3/FADD/PRXL2A/MYH9/FAM20C/JUNB/IL15/BATF/ITGB6/SBNO2/LTBR/PIR/JUN/MYC/UBASH3B/RUNX1/SRC/CSF2/SNX10/IFI16
GOBP_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS 421 0.3683784 1.525097 0.0002842 0.0079098 0.0064983 2650 SLC5A5/EDNRA/ALOX15/CYP51A1/MVD/HMGCS1/EBP/PSAT1/FDPS/LSS/PCSK9/DHCR7/SLC7A11/MAOA/MSMO1/ACSS2/HMGCR/INSIG1/CH25H/PCK2/ADH1C/HSD17B7/KL/IDI1/FGFR4/DUOX2/LRAT/LDLR/STARD4/ALDH1A3/DUOXA1/FDFT1/NPC1/HRH1/TG/SQLE/NSDHL/ALPL/ACLY/SC5D/BCL2/ALOX15B/NFE2L1/GCNT4/LCAT/DUOXA2/TTPA/FGF2/G6PD/RDH11/GATA3/DUOX1/SRD5A3/APOE/TM7SF2/ERG28/PLA2G4A/GOT1/CYP27B1/MVK/P2RY1/SLC5A3/SDR16C5/SCARB1/HIF1A/DHRS7/IDH1/TNF/CYP2C18/CDH3/APOL2/ATP8B1/CYP46A1/SPHK1/RETSAT/GCH1/PTAFR/GPD2/BMP2/HSD3B7/TPK1/SREBF2/APOBR/CYP2C9/ITGAM/APOL1/ACADL/P2RY6/GBA2/SNCA/SGPP2/ZEB2/RDH13/ITPKA/CYP3A5/DGKQ/GALK1/MFSD12/DHDDS/LIPA/PDXK/GDPD3/BMP6/ACER2/DHCR24/INPP1/ITPK1/ASAH2/CYB5R3/GPER1/SGPP1/OSBPL1A/GFI1/DRD1/PNKD/CLN6/PIP4P1/GIPC1/TIGAR/ITPKC/CYP2E1/PPARD/SPTSSA/PTS
GOBP_EXTERNAL_ENCAPSULATING_STRUCTURE_ORGANIZATION 236 0.4092558 1.584740 0.0003104 0.0084747 0.0069623 1938 HAS2/DPP4/LOXL4/MMP1/SLC39A8/VIT/POSTN/COL13A1/KLK7/ADAMTS14/PHLDB2/HAS3/ADAM8/MMP16/FAP/FGFR4/LUM/NTNG1/NID2/MMP19/NOXO1/CLASP1/MMP25/SMOC2/NFKB2/SH3PXD2B/WASHC1/RIC1/HSD17B12/PXDN/MMP17/COLGALT2/SERAC1/CAPG/ADAMTSL3/SOX9/TNF/SULF1/DDR2/ADAMTS9/CAV2/FOXF2/SCX/BMP2/ENG/ADAMTS17/MMP11/COL22A1/GREM1/LOX/GSN/SPINK5/COL17A1/MMP28/SERPINH1/MMP10/LAMB3/PLOD3/SPINT2/COLGALT1/EGFL6/BMP1/COL14A1
GOBP_REGULATION_OF_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 269 -0.3681810 -1.529097 0.0003090 0.0084747 0.0069623 1957 KANK2/PBX1/RRM1/CHEK1/ESPL1/GPNMB/STIL/BRCA1/CDC7/MTBP/ADAMTS1/HSPA2/ABRAXAS1/CDC25A/BLM/HECW2/STOX1/FHL1/FBXO5/ANAPC4/CCNB1/ORC1/TRIP13/CDC14A/E2F1/E2F7/CCL2/TTK/CDT1/CDCA5/NDC80/KIF14/MAD2L1/CENPF/CENPE/PLK1/TICRR/CDK1/ANLN/RRM2/DTL/BUB1/GTSE1/DLGAP5/CDC25C/UBE2C/BUB1B
GOBP_BEHAVIOR 411 0.3625831 1.501929 0.0003135 0.0085096 0.0069910 1754 NTRK1/CLDN5/SLC18A2/DPP4/GDNF/ARC/LYPD1/BRINP1/ADM2/FZD9/ADCY5/CNR1/SLC7A11/SGK1/AFF2/MME/BDNF/HTR1D/HMGCR/LDLR/ALDH1A3/SGIP1/MAPK8IP2/ACE/NPC1/MFSD2A/HRH1/NTRK2/HOMER2/UCHL1/GDF15/FOS/IDO1/BCL2/TMOD1/GCNT4/RELN/LPAR5/EGR1/FGF12/CPT1A/ARRB2/APOE/EGR2/ITPR3/P2RY1/GJB4/MMP17/DAB1/HIF1A/FOSL1/PTGS2/CIART/MAFG/KCNA2/SYT11/CSTB/ATP8A2/BRSK1/PER3/THBS1/KRAS/FYN/NR4A3/ABCA7/PRKCG/NDRG4/P2RX4/SNCA/FADD
GOBP_POSITIVE_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY 11 -0.8190624 -1.862302 0.0003198 0.0086031 0.0070678 337 CDC20B/PLK1/CDC20/UBE2C
GOBP_CELL_JUNCTION_ASSEMBLY 339 0.3791513 1.532043 0.0003206 0.0086031 0.0070678 2855 NTRK1/CLDN5/THY1/PTPRO/ACHE/CDH6/CLDN22/BDNF/SFRP1/GJB6/PHLDB2/GJB2/MAP1B/GPC6/ACE/LRRTM2/NTRK2/NTRK3/BCL2/VEGFA/FZD5/CDH19/ANK2/EPHB3/CLASP1/CD9/GJA4/LRRC4/LRFN4/EPHA3/SLK/VCL/OCLN/ESAM/KDR/RHOD/PKP2/TNF/UGT8/NRCAM/FZD1/MYO1C/VSTM5/CRB3/IL1RAPL2/DUSP3/CLDN4/VMP1/PCDHB2/IGFN1/DLG1/EPHA2/PRKCH/THBS1/SLIT1/GREM1/ITGA6/LSR/NTN1/SLC9A1/COL17A1/SNCA/TJP1/RAC1/MARVELD3/CTTN/CLDN9/ACTB/RAB29/CLDN7/WDR1/FLCN/DLG5/PIP5K1A/PDLIM5/RHOC/DAPK3/S100A10/SH3BP1/EFNA5/TRPV4/PCDHB6/SHANK3/EIF4G1/PLEC/ACTN1/DRD1/SRC/HDAC7/CLDN1/FGF13/TLN2/EPHA7/STRN/PAK2/BCR/LRRN3/CAMSAP3/ACTG1/GPC4/SETD5/RAP1A/CLDN12/CAV1/TESK2
GOBP_RESPONSE_TO_TYPE_I_INTERFERON 58 0.5929659 1.871820 0.0003287 0.0087200 0.0071639 1827 ZBP1/CH25H/ISG15/OAS3/NLRC5/OAS1/MX1/IFIT1/IFITM1/USP18/IRF7/IFI27/SHMT2/OAS2/IFITM3/MYD88/SHFL/ADAR/FADD/STAT1/IRAK1
GOBP_INTERLEUKIN_1_PRODUCTION 76 0.5514392 1.841574 0.0003275 0.0087200 0.0071639 1547 IL1R2/TLR4/NOD2/GBP5/CD36/AIM2/TRIM16/FZD5/EGR1/ARRB2/ANXA1/PANX2/S1PR3/PML/TMEM106A/CEACAM1/MYD88/TNF/ZC3H12A/CX3CL1/HK1/SPHK1/NLRP2/ARG2/LGALS9/SERPINB1/NLRP10/ERRFI1
GOBP_LYMPHOCYTE_MIGRATION 72 0.5490673 1.814899 0.0003383 0.0089246 0.0073320 2678 CCL26/CXCL10/CCL4/CH25H/CXCL11/ADAM8/STK10/CCL22/ARTN/CXCL16/SLC12A2/GATA3/CD200R1/RIPK3/S100A7/ICAM1/CX3CL1/CCL5/HSD3B7/OXSR1/FADD/SLC8B1/WASL/ITGB7/AKT1/MSN/ADAM17/GAS6/PLEC/CCL20/IL27RA/MIA3/FUT4
GOBP_REGULATION_OF_AUTOPHAGY 306 0.3933286 1.580679 0.0003472 0.0091077 0.0074824 4771 ADRA1A/PTPN22/TRIB3/PRKD1/ATP6V1C2/NOD2/ATP6V0D2/NPC1/UCHL1/BCL2/PLK3/DDIT3/DEPP1/FZD5/SESN2/DAPK2/HSPB8/EEF1A2/TICAM1/MET/WASHC1/LAMP3/HIF1A/GPSM1/KDR/ZC3H12A/ATP6V0A2/RUBCN/HMOX1/OPTN/SREBF2/TRIM14/RRAGC/RRAGD/TPCN2/SNCA/CAMKK2/TRIM21/TBC1D14/ATP13A2/RIPK2/CTTN/PIP4K2A/HDAC6/ATP6V1E2/RASIP1/FLCN/ACER2/DEPDC5/MTCL1/DAPK3/AKT1/BOK/NEDD4/EIF4G1/FOXK1/TRIM5/CPTP/EPM2A/ATG2A/NOD1/TIGAR/NRBP2/CALCOCO2/IFI16/LARP1/SIRT2/HAX1/IKBKG/FOXK2/TRIM22/SMCR8/PIP4K2C/RPTOR/TSC1/HTT/PLK2/ATG7/TP53/RAB8A/ATP6V1H/SPTLC2/ERN1/EXOC8/PHF23/SNX30/UBQLN1/CDK5R1/MTOR/TAB3/GNAI3/BCL2L11/PIK3CB/RMC1/SLC25A5/TP53INP2/TSPO/TRIM65/TBC1D25/RHEB/DRAM1/VPS29/MAPK3/ATP6V0A1/USP36/TFEB/ATP6V0B/ATP6V1B2/ATP6V0D1/RALB/VPS26A/TAB2/SH3BP4/NUPR1/CAPN1/FBXL2/SMG1/TECPR1/TLK2/MCL1/ATG16L1/CSNK2A2/UBQLN4/GSK3A/RNF41/RAB3GAP2/DNM1L/ATP6V0E1/SPTLC1/GSK3B/PARL/KEAP1/GOLGA2
GOBP_PROTEIN_LOCALIZATION_TO_CHROMOSOME 88 -0.4966993 -1.764746 0.0003640 0.0094953 0.0078008 3499 ZWILCH/BRCA2/RUVBL2/WRAP53/SLF1/IK/MSH2/MRNIP/ESR1/EZH2/LRWD1/HASPIN/FAM47E/MTBP/MCM8/KNL1/TTK/H1-5/CDT1/CDCA5/NDC80/PLK1/CDK1/ESCO2
GOBP_FEMALE_MEIOTIC_NUCLEAR_DIVISION 27 -0.6787145 -1.950297 0.0003742 0.0097072 0.0079749 918 FBXO5/FMN2/HSF2BP/TRIP13/TTK/NDC80/CCNB2/NCAPH/PLK1/TOP2A
GOBP_INORGANIC_ANION_TRANSPORT 133 0.4943595 1.784212 0.0003975 0.0102532 0.0084234 1723 ANO1/GABRA4/SLC5A5/SLC26A4/CA2/SLC26A9/SLC5A1/SLC39A8/TTYH2/ANO2/LRRC8D/CLIC2/ANO4/TG/CLIC3/SLC12A2/LRRC8A/ATF4/CLIC4/ENPP1/SLC4A9/LRRC8B/SLC26A6/SLC26A11/SLC1A4/ANO8/SLC4A3/ATP8B1/CLDN4/LRRC8C/PTAFR/CLCN6/ANO7/SLC25A3/SLC12A4/APOL1/P2RY6/VDAC2
GOBP_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION 81 -0.4996339 -1.761363 0.0004049 0.0103312 0.0084875 918 FBXO5/CCNB1/TRIP13/PTTG1/TTK/CDT1/NDC80/MAD2L1/CENPF/PLK1/BUB1/TOP2A/BUB1B
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION 187 0.4342450 1.629216 0.0004037 0.0103312 0.0084875 2887 HAS2/DPP4/SOCS1/RASGRP1/SELP/THY1/CD274/PTPN22/PDCD1LG2/CD55/CD44/ADAM8/NOD2/IL4I1/PRKCQ/EBI3/IL1A/CD47/CD70/GATA3/SLC7A1/CD86/ANXA1/CD276/HLA-DOB/TNFSF9/NFKBID/CARD11/DUSP10/IL23A/TNF/CD83/IL4R/PTAFR/ZBTB7B/CCL5/ST3GAL4/LGALS9/FYN/NR4A3/FADD/IL1RL2/IRAK1/RIPK2/CD46/TNFRSF13C/MAP3K8/IL15/BCL10/AP3D1/HLA-DQB2/AKT1/RELA/RUNX1/SRC/PTPN11/IL27RA/IL6ST/FUT4/ALOX5/SYK/SKAP1/CSK/CAV1/NFAT5/IGF2
GOBP_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS 262 0.4005874 1.574032 0.0004080 0.0103523 0.0085049 2887 NOS2/PLA2G3/C1QTNF1/APOC1/TRIB3/SLC2A6/DHCR7/CNR1/SLC7A11/INSIG1/NNMT/PPARG/FGFR4/LDLR/STARD4/MFSD2A/HRH1/ELOVL5/PHLDA2/PPP1R3G/ANTKMT/SESN2/EGR1/CPT1A/APOE/PMAIP1/FBP1/CYP27B1/ANXA1/P2RY1/ENPP1/ERFE/HIF1A/SOX9/CEACAM1/PTGS2/MLXIPL/TNF/SLC27A4/IRS2/PTAFR/APPL2/BMP2/PPP1R3C/PPTC7/NR4A3/ACADL/P2RY6/NOS1/SNCA/FAM3C/NLN/DGKQ/TAFAZZIN/ENTPD5/BMP6/SLC35B4/FLCN/MID1IP1/ENO1/AKT1/KAT2B/TMSB4X/RORA/MYC/SELENOS/GPER1/FOXK1/GFI1/SRC/CLYBL/ARPP19/TIGAR/PRXL2C/PPARD/GPT/PPARGC1A/CAV1/DUSP12/MIDN/PFKFB2/IGF2
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION 29 -0.6605761 -1.923393 0.0004280 0.0107134 0.0088015 2836 RAD51B/DYRK3/ATAD5/PBX1/RRM1/CDC7/HSPA2/CDC25A/STOX1/FBXO5/CCNB1/CDK1/DTL/CDC25C
GOBP_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION 23 -0.6919580 -1.923140 0.0004264 0.0107134 0.0088015 1344 KNTC1/ZWILCH/IK/HASPIN/MTBP/KNL1/TTK/CDT1/NDC80/CDK1
GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY 48 0.5989110 1.805704 0.0004314 0.0107134 0.0088015 1780 NOS2/RASGRP1/SERPINB4/PVR/SERPINB9/ARRB2/MICA/RAET1E/NECTIN2/RIPK3/CEACAM1/IL23A/ICAM1/LGALS9/ITGAM/FADD/CXCL6
GOBP_SKIN_DEVELOPMENT 207 0.4147205 1.574163 0.0004297 0.0107134 0.0088015 1689 SPRR2E/LGR5/SPRR3/SPRR2F/SPRR2A/KRT16/SPRR1A/ZBED2/PAX6/SPRR2D/BCL11B/ALOXE3/NSDHL/EREG/FA2H/TRIM16/BCL2/ALOX15B/CSTA/IL1A/EDAR/FOXQ1/GRHL3/GJB3/SFN/ADAM9/MET/CLIC4/CYP27B1/ANXA1/OVOL1/FOSL2/LCE1E/S100A7/MSX2/SOX9/ZFP36/TNF/SLC27A4/CDH3/CLDN4/YAP1/ATP8A2/EPHA2/PRKCH/ELOVL1/TNFRSF19/ERRFI1/ITGA6/LSR/IRF6/SPINK5
GOBP_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY 342 0.3705499 1.497377 0.0004380 0.0108202 0.0088893 4015 CCL26/SELP/ALOX15/MMP1/TLR4/TRABD2A/WARS1/ISG15/CDC42EP5/MAP1B/GBP5/ARHGEF5/SLIT2/CD36/MAP2/PPP2R5B/VEGFA/TMOD1/LCAT/CLASP1/CDC42EP1/ARHGAP40/APOE/TICAM1/TWF2/MET/TMC8/HCK/STX1A/BAK1/BIN1/BIK/CAPG/OCLN/SOX9/ESAM/MYD88/TNF/TMSB10/SNX9/FLII/PIEZO1/DBN1/SVIL/DLG1/ABCA3/GSN/ARPC5L/SSH1/GBA2/VDAC2/SNCA/RAC1/EIF2AK2/VASP/CTTN/KANK3/NCLN/HDAC6/SEPTIN8/SORL1/RASIP1/SPTBN5/RHOC/STXBP5/MSN/TMSB4X/EIF4G1/RANGRF/SRC/PTPN11/CPTP/CSF2/FERMT1/BID/LGALS3/CAMSAP3/SYK/SIRT2/ARPC4/HAX1/TRIOBP/SKAP1/TMOD2/AIDA/IKBKE/ISL1/PFN1/H3-3B/INPP5J/FERMT2/SPTBN1/TFRC/GIT1/SPTAN1/CTNNBIP1/MYADM/WASHC2C/TP53/FBLIM1/RNF4/ARPC5/CYRIB/RAB3A/NCKAP1/SLF2/PREB/AJUBA/FNIP1/NAPA/HSPA5/ARPC1B/ANKRD27/CDK5R1/TMOD3/FNIP2/ARPC1A/ARFGEF1/HIP1R/ARF6/MTOR/NRG1/COTL1/BCL2L11/CYFIP1/TIRAP/HCLS1
GOBP_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION 51 -0.5515787 -1.784784 0.0004515 0.0110942 0.0091144 918 MTBP/FBXO5/CCNB1/TRIP13/TTK/CDT1/NDC80/FBXO43/MAD2L1/CENPF/PLK1/BUB1/BUB1B
GOBP_AMEBOIDAL_TYPE_CELL_MIGRATION 364 0.3720742 1.509697 0.0004649 0.0113051 0.0092877 2627 HAS2/DPP4/GDNF/EDNRA/HYAL1/PRSS3/KRT16/PRKD1/HBEGF/SEMA3B/PPARG/FAP/KLF4/FGFBP1/S100P/NR4A1/SLIT2/MIR200A/DLL4/PKN3/AMOT/HDAC9/VEGFA/FGF2/CLASP1/TNFSF12/GATA3/SMOC2/ANXA3/APOE/SEMA3D/ADAM9/EDN1/MET/ANXA1/KITLG/EPPK1/SCARB1/NRP2/HIF1A/PML/SOX9/CEACAM1/DUSP10/PTGS2/KDR/SEMA7A/TNF/ZC3H12A/PTP4A3/DDR2/ADAMTS9/ARID5B/HMOX1/SEMA3A/SEMA4C/EPHA2/APPL2/ENG/PLEKHG5/SEMA6A/THBS1/BCAR1/GADD45A/CCN3/GREM1/TESK1/P2RX4/ARSB/STAT1/SLC8A1/RAC1/PTPRG/ZEB2/AKT3/ACTA2/MYH9/MARVELD3/NRTN/ALX1/RHOB/SCG2/HDAC6/ITGB7/CSNK2B/SGPL1/TIMP1/PIP5K1A/GNA12/AKT1/JUN/SH3BP1/TGFBR1/TMSB4X/ADAM17/ZFAND5/ITGA3/TACSTD2/RFFL/PLEC/SRC/HDAC7/PTPN11/GIPC1/MAPRE2/FERMT1/ACVR1C/PPARD/MIA3
GOBP_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS 373 0.3666323 1.494403 0.0004639 0.0113051 0.0092877 3386 SOCS1/THY1/APOC1/PTPN22/PTPRO/TRIB3/WARS1/PPP1R16B/HMGCR/SFRP1/PPARG/SPRY4/PAX6/LPIN1/SLIT2/PTPRQ/UCHL1/NTRK3/PTPRH/HHEX/CBLC/ARRB2/APOE/SFN/FBP1/XDH/GRB10/WASHC1/ENPP1/ZBED3/CDKN1C/MFHAS1/TRIB1/BAK1/OCLN/CEACAM1/DUSP10/TRIB2/MLXIPL/TNF/ZC3H12A/NIBAN1/PPP1R15B/RUBCN/SOCS3/DUSP3/IRS2/DBNDD1/RGS2/DUSP7/SPRED2/PARP14/BMP2/ENG/CDKN2B/GADD45A/ERRFI1/GREM1/FKBP1B/DUSP6/SERPINB3/SH2B3/TESK1/SPAG9/SNCA/ADAR/ZGPAT/SLC8A1/ANKLE2/PIP4K2A/TNFAIP3/DGKQ/LATS2/CHMP6/SORL1/MASTL/RASIP1/GPRC5A/CDKN2A/CNKSR3/PRNP/FLCN/CDKN1A/PTK6/MICAL1/AKT1/KAT2B/JUN/PPP4R2/ZFYVE28/UBASH3B/EIF4G1/CHP1/PIK3IP1/PLEC/DBNDD2/ARPP19/TIGAR/PAK2/CADM4/LGALS3/YWHAG/SIRT2/SMPD1/CSK/CAV1/MIDN/AIDA/HEXIM1/PRKAR1B/SIRT6/INPP5J/CBL/SMCR8/PIP4K2C/LRRK1/PKIA/SWAP70/HEG1/INPP5F/GIT1/SPRED1/IBTK/MYADM/NCOR1/UBE2B/PDE4D/TP53
GOBP_ORGANIC_ACID_BIOSYNTHETIC_PROCESS 237 0.4009139 1.553395 0.0004791 0.0115907 0.0095222 1792 PLA2G3/APOC1/ALOX15/CBS/TRIB3/TBXAS1/FADS2/PSAT1/ELOVL6/LIPG/INSIG1/FGFR4/FADS1/STARD4/ALDH1A3/ASNS/HAAO/ELOVL5/BCAT1/ALOXE3/SCD/PYCR1/FA2H/ACLY/PHGDH/IDO1/ALOX15B/LIPH/FASN/MTHFD1L/DPYD/EDN1/ELOVL7/PLA2G4A/GOT1/CTH/ANXA1/HSD17B12/SHMT2/GGT5/CEACAM1/PTGS2/MLXIPL/ACOT7/CYP46A1/GGT7/LTA4H/HSD3B7/ELOVL1/CYP2C9/SERINC5/ACADL/ELOVL4/ACACA/PLOD3/NAGS
GOBP_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION 50 -0.5687773 -1.829090 0.0004912 0.0117603 0.0096616 2402 RFC5/ZRANB3/CHTF8/CDC7/BLM/GINS1/GINS2/FBXO5/MCIDAS/E2F7/DSCC1/CDT1/GMNN/DACH1/TICRR
GOBP_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS 264 0.3967322 1.561448 0.0004909 0.0117603 0.0096616 2787 CISH/PLA2G3/SOCS1/PNPLA3/APOC1/ALOX15/LDLR/LPIN1/MFSD2A/PLA2G4C/ABHD4/ENPP6/SOCS2/PLAAT1/LCAT/LIPH/FGF2/PLA2G7/PLA2G4A/GPCPD1/SCARB1/SERAC1/GPAT3/LPCAT4/FAR1/SOCS3/PISD/PLCB3/ABCA3/TMEM150A/PIGW/SERINC5/PTPMT1/SELENOI/PLSCR1/ITPKA/GPAT4/PGAP4/PIP4K2A/DGKQ/TAFAZZIN/ACP6/GDPD3/CAPN2/PIP5K1A/INPP1/MBOAT1/PIK3C2B/PLD2/MTMR12/INPPL1/DGKA/PTDSS1/PIP4P1/PITPNM2/ITPKC/TTC7A/ABHD3/OSBPL5/ACSL3
GOBP_SERTOLI_CELL_DEVELOPMENT 10 0.8535331 1.835556 0.0004984 0.0118289 0.0097179 1121 NTRK1/IL1A/SOX9
GOBP_PROTEIN_LOCALIZATION_TO_CILIUM 66 -0.5253333 -1.767749 0.0004991 0.0118289 0.0097179 4227 CDK20/BBS1/ATP6V1D/DNAAF11/ARL6/TCTN1/IFT20/ZMYND10/ARL13B/TMEM107/ROPN1B/ODAD4/ARL3/BBS9/CCDC66/CCDC39/BBIP1/IFT122/TCTN2/WDR19/TBC1D32/MAPK15/SPATA7/TUB/TTC21A/CFAP58/IFT140/CC2D2A/WDR35/IFT80/DYNC2H1/LZTFL1/EFCAB7/DZIP1L/BBS4/TTC21B/CROCC/ROM1
GOBP_CYTOKINE_PRODUCTION_INVOLVED_IN_INFLAMMATORY_RESPONSE 43 0.6275177 1.859701 0.0005267 0.0123691 0.0101617 1591 NOS2/PLA2G3/IL1R2/TLR4/NOD2/GBP5/ADCY7/TICAM1/HIF1A/MYD88/TNF/ZC3H12A/APPL2/CARD9
GOBP_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION 444 0.3574460 1.483131 0.0005272 0.0123691 0.0101617 2837 NTRK1/GDNF/ARC/THY1/LGR6/EDNRA/DLX5/PTPRO/RTN4R/SDC2/BDNF/SEMA3B/CRMP1/MAP1B/GRXCR2/PAX6/NTNG1/BCL11B/MAPK8IP2/FOXD1/MFSD2A/CDHR1/SLIT2/NTRK2/PRKCQ/UCHL1/ARTN/MAP2/BCL2/VEGFA/TNIK/OLFM1/RELN/EPHB3/LRP8/ZNF365/GATA3/APOE/SEMA3D/PHACTR1/PLS1/TUBB3/EDN1/EGR2/TWF2/CHODL/ANOS1/EPHA3/DAB1/NRP2/VCL/BRSK2/PLXNA3/SEMA7A/NRCAM/NIBAN2/EPHA10/ISLR2/DBN1/SEMA3A/SEMA4C/ATP8A2/NSMF/ECE1/EPHA2/BRSK1/SEMA6A/FYN/RHOG/SLIT1/NDEL1/NTN1/DPYSL2/IGSF9/RUFY3/RAC1/ITPKA/KIF5C/VASP/CTTN/HDAC6/WASL/MYOT/RAPH1/ACTB/CHN1/SCRIB/SPP1/PDLIM5/LIMK1/EFNA5/NGEF/PARP6/NEDD4/SHANK3/PICALM/SCN1B/FOXB1/MCF2/PTPN11/FGF13/EPHA7/PAK2/SHTN1/STK25/MAP2K1/CFL1/COBL/TIAM1/DAG1/TTL/SEMA4F/LAMA3/EMB/TIAM2/LAMB2/TRIOBP/DOCK7
GOBP_SPINDLE_ASSEMBLY 119 -0.4431214 -1.651856 0.0005317 0.0124121 0.0101971 1235 GOLGA8M/ABRAXAS1/STARD9/KIF11/FBXO5/KIFC1/KIF4A/SPAG5/NDC80/TPX2/CCNB2/NEK2/PLK1/KIF15/GOLGA8H/CDC20/ASPM/MYBL2
GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS 209 0.4095788 1.557430 0.0005542 0.0128743 0.0105768 2385 IL13RA2/C8B/CD274/TLR4/IL1RL1/CTSC/RSAD2/CD55/NOD2/IL4I1/PVR/PRKCQ/BACH2/EBI3/FZD5/UNC13D/CLCF1/CD70/IRF7/GATA3/TNFSF13/MICA/RELB/NFKB2/PLA2G4A/ANXA1/NECTIN2/HLA-DOB/IL18R1/RIPK3/NFKBID/ARID5A/CEACAM1/IL23A/MYD88/ICAM1/TNF/ZC3H12A/AHR/IL4R/TRPM4/ZBTB7B/NLRP10/CARD9/FADD/RIPK2/IL20RB/C1S/RNF8/TNFAIP3/CD46/SHLD2/BATF/BCL10/HLA-DQB2/HLA-F/ADAM17/RORA/C2
GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION 270 0.3876367 1.529137 0.0005692 0.0131565 0.0108087 2565 PLA2G3/DPP4/SOCS1/RASGRP1/SELP/THY1/CD274/TLR4/PTPN22/PDCD1LG2/IL1RL1/CTSC/CD55/ADAM8/NOD2/IL4I1/PRKCQ/EBI3/BCL2/IL1A/TOX/CLCF1/CD47/CD70/GATA3/SLC7A1/TNFSF13/TICAM1/CD86/PLA2G4A/ANXA1/CD276/NECTIN2/HLA-DOB/TNFSF9/NFKBID/CARD11/DUSP10/IL23A/MYD88/TNF/GAB2/CD83/IRS2/IL4R/PTAFR/ZBTB7B/CCL5/LGALS9/THBS1/FYN/NR4A3/ITGAM/IL15RA/AXL/JUND/FADD/IL1RL2/ACTA2/RIPK2/CD46/TNFRSF13C/MAP3K8/IL15/SHLD2/BCL10/CDKN1A/AP3D1/HLA-DQB2/AKT1/HLA-F/GAS6/CD177/RUNX1/STX4/SRC/PTPN11/IL27RA
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION 99 -0.4803786 -1.755631 0.0006085 0.0139962 0.0114985 2836 RAD51B/RGCC/NANOGP8/DYRK3/CENPJ/EZH2/MAPK15/SASS6/ATAD5/PBX1/RRM1/ESPL1/STIL/CDC7/MTBP/ADAMTS1/HSPA2/CDC25A/STOX1/FBXO5/ANAPC4/CCNB1/CDT1/CDCA5/CDK1/RRM2/DTL/DLGAP5/CDC25C/UBE2C
GOBP_IMPORT_ACROSS_PLASMA_MEMBRANE 124 0.4740255 1.695058 0.0006296 0.0144099 0.0118383 2338 TRPV6/ATP12A/SLC9A3/SLC5A1/SLC39A8/SLC7A11/KCNJ16/LRRC8D/SLC6A14/CD36/SLC3A2/SLC12A2/SLC7A5/LRRC8A/SLC7A1/HCN2/SLC1A5/SCNN1D/SLC5A3/SLC36A1/ACSL1/SLC1A4/TRPV3/TNF/IRS2/LRRC8C/RGS2/DLG1/TRPM4/SLC15A3/THBS1/FYN/SLC12A4/ATP1B1/SLC9A1/SLC6A9/SLC9A4/SLC8A1/SLC39A4/SLC39A14/PRNP/ATP1A1/GRM1/AKT1/TRPV4
GOBP_CELL_CYCLE_G2_M_PHASE_TRANSITION 142 -0.4188731 -1.614639 0.0006524 0.0148361 0.0121885 3038 CHEK2/NOP53/AURKA/RAD51B/ING4/MRNIP/USH1C/DYRK3/KDM8/MRE11/CLSPN/ATAD5/CCNA2/PBX1/RRM1/CHEK1/BRCA1/CDC7/MELK/HSPA2/PKMYT1/ABRAXAS1/CDC25A/BLM/STOX1/FHL1/FBXO5/CCNB1/ORC1/NEK10/FOXM1/FBXL22/CIT/NDC80/KIF14/CENPF/CCNB2/PLK1/TICRR/CDK1/DTL/CDC25C
GOBP_TISSUE_MIGRATION 268 0.3855299 1.520229 0.0006578 0.0148361 0.0121885 2627 HAS2/DPP4/HYAL1/PRSS3/KRT16/PRKD1/HBEGF/PPARG/FAP/KLF4/FGFBP1/S100P/NR4A1/SLIT2/MIR200A/DLL4/PKN3/AMOT/HDAC9/VEGFA/FGF2/CLASP1/TNFSF12/GATA3/SMOC2/ANXA3/APOE/ADAM9/EDN1/MET/ANXA1/EPPK1/SCARB1/NRP2/HIF1A/SOX9/CEACAM1/DUSP10/PTGS2/KDR/TNF/ZC3H12A/PTP4A3/ADAMTS9/HMOX1/SEMA3A/EPHA2/PLEKHG5/THBS1/BCAR1/GADD45A/CCN3/GREM1/TESK1/P2RX4/ARSB/STAT1/RAC1/PTPRG/ZEB2/AKT3/ACTA2/MYH9/MARVELD3/RHOB/SCG2/HDAC6/CSNK2B/AKT1/JUN/SH3BP1/TGFBR1/TMSB4X/ADAM17/ITGA3/TACSTD2/SRC/HDAC7/PTPN11/GIPC1/MAPRE2/FERMT1/PPARD/MIA3
GOBP_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY 355 0.3648646 1.482570 0.0006566 0.0148361 0.0121885 2898 NTRK1/TLR4/PRKD1/SGK1/ADAM8/PPARGC1B/PPARG/NOD2/KLF4/ARHGEF5/NLRC5/PRKCQ/CD36/AIM2/PPP2R5B/VEGFA/DDIT3/RTKN2/RELN/LPAR5/LRP8/ANXA3/ARRB2/TICAM1/EDN1/CTH/ENPP1/HCK/IL18R1/RIPK3/TRIB1/IRAK2/NFKBIA/MSX2/CARD11/FOSL1/MYD88/SLCO3A1/TNF/CEBPG/ZC3H12A/CAMK1D/PSMA6/FZD1/DDR2/CX3CL1/ARID5B/HMOX1/ID3/SPHK1/RPS6KA4/NLRP2/BMP2/PRKCH/LGALS9/TRIM14/GREM1/CARD9/PIM1/ANXA4/HES6/TRIM21/EIF2AK2/IRAK1/RBCK1/RIPK2/TRAF5/TRIM25/TNFAIP3/NFKBIE/PARP10/CDKN2A/NFKBIB/PRNP/BCL10/AKT1/TMSB4X/MDFI/BHLHE40/NKX3-1/GAS6/CHP1/RELA/TRIM5/GFI1/CYLD/GLIS2/NOD1/BCL3/WFS1/DDRGK1/SYK/PPARGC1A/CAV1/IKBKG/MAP3K13/CRTC3/IKBKE
GOBP_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS 17 -0.7554980 -1.936549 0.0006702 0.0148383 0.0121903 1441 ECRG4/ANAPC4/CDC20B/PLK1/CDC20/UBE2C
GOBP_XENOBIOTIC_METABOLIC_PROCESS 82 -0.4908296 -1.723640 0.0006737 0.0148383 0.0121903 1585 GSTM2/FMO4/GSTM1/UGT1A7/HNF4A/CYP2C8/UGT1A5/CYP2W1/SULT1B1/ACSM1/GSTA3/EPHX1/AKR1C1/CYP2B6/UGT1A8/FMO5/NAT1/CYP2F1/FMO2/CYP2A6/ALDH3A1/GSTA4/CYP26B1/ABCB11/GSTA1/GSTA2
GOBP_REGULATION_OF_HORMONE_SECRETION 159 0.4408851 1.629708 0.0006723 0.0148383 0.0121903 2614 NOS2/ANO1/PLA2G3/C1QTNF1/ADCY5/SLC9B2/CNR1/SFRP1/PCK2/PPARG/LRRC8A/CPT1A/EDN1/DOC2B/ANXA1/RAB11FIP1/P2RY1/STX1A/HIF1A/BRSK2/RAB8B/TNF/IRS2/LIF/GPR27/TRPM4/CCL5/CCN3/FKBP1B/ACSL4/SLC8B1/AACS/VSNL1/GABBR1/BMP6/PIM3/MCU/EIPR1/TFR2/SPP1/EFNA5/RAB11FIP5/NKX3-1/GPER1/STX4/PTPN11/ACVR1C/PPARD
GOBP_DNA_DEPENDENT_DNA_REPLICATION 155 -0.4076187 -1.590409 0.0006720 0.0148383 0.0121903 2429 TOPBP1/MMS22L/PRIM1/POLA1/OOEP/RPA1/MCM6/SAMHD1/SETMAR/EME1/E2F8/MCM2/TIMELESS/BRCA2/MCM7/POLD1/RFC3/WRN/PRIMPOL/FANCM/LRWD1/RFC5/WDHD1/MRE11/ATAD5/ZRANB3/CHTF8/CENPS/RRM1/DNA2/POLE2/LIG1/ZGRF1/CDC7/BLM/POLN/GINS1/GINS2/POLA2/FBXO5/RECQL4/ORC1/POLQ/MCIDAS/E2F7/DSCC1/CDT1/GMNN/DACH1/CCNE2/TICRR/GMNC/MCM10
GOBP_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY 222 0.4098825 1.576178 0.0006727 0.0148383 0.0121903 1909 NTRK1/TLR4/PRKD1/ADAM8/PPARGC1B/PPARG/NOD2/ARHGEF5/PRKCQ/CD36/AIM2/PPP2R5B/VEGFA/DDIT3/RTKN2/RELN/LPAR5/LRP8/ANXA3/TICAM1/EDN1/CTH/IL18R1/RIPK3/IRAK2/CARD11/FOSL1/MYD88/SLCO3A1/TNF/CEBPG/CAMK1D/PSMA6/FZD1/DDR2/CX3CL1/ARID5B/SPHK1/RPS6KA4/BMP2/PRKCH/LGALS9/TRIM14/GREM1/CARD9/TRIM21/EIF2AK2/IRAK1/RBCK1/RIPK2/TRAF5/TRIM25
GOBP_REGULATION_OF_CHEMOTAXIS 161 0.4477920 1.654237 0.0006817 0.0149440 0.0122771 1831 CCL26/DPP4/TNFAIP6/PTPRO/CXCL10/PRKD1/CCL4/SEMA3B/NOD2/SLIT2/CXCL8/ST6GAL1/ARTN/NTRK3/F3/VEGFA/FGF2/DAPK2/SMOC2/PLA2G7/SEMA3D/EDN1/MET/STX3/S100A7/PLXNA3/IL23A/KDR/SEMA7A/CAMK1D/DUSP3/SEMA3A/SEMA4C/CCL5/LGALS9/SEMA6A/THBS1/CCN3/SLIT1/GREM1/MMP28/P2RX4/OXSR1/RAC1/SLC8B1
GOBP_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY 118 0.4832675 1.708159 0.0006943 0.0151486 0.0124452 1477 SH2D1B/RASGRP1/SERPINB4/RSAD2/CD55/NOD2/IL4I1/PVR/RAET1G/SERPINB9/FZD5/CLCF1/GATA3/ARRB2/TNFSF13/MICA/RAET1E/NECTIN2/IL18R1/RIPK3/ARID5A/CEACAM1/IL23A/TNF/AHR/TRPM4/LGALS9
GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY 78 0.5321160 1.789430 0.0006995 0.0151902 0.0124794 1835 NOS2/RASGRP1/SERPINB4/CTSC/ULBP1/PVR/RAET1G/SERPINB9/UNC13D/ARRB2/MICA/RAET1E/NECTIN2/ULBP2/RIPK3/CEACAM1/IL23A/MYD88/ICAM1/CEBPG/LGALS9/ITGAM/RNF19B/TUBB/FADD/CXCL6/ULBP3
GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY 161 0.4465230 1.649549 0.0007148 0.0154076 0.0126580 3190 NTRK1/CLDN5/THY1/BDNF/SFRP1/PHLDB2/GPC6/ACE/LRRTM2/NTRK2/NTRK3/VEGFA/FZD5/EPHB3/CLASP1/LRFN4/EPHA3/SLK/VCL/KDR/TNF/FZD1/MYO1C/VSTM5/CRB3/IL1RAPL2/DUSP3/EPHA2/PRKCH/THBS1/SLIT1/GREM1/NTN1/SLC9A1/SNCA/TJP1/RAC1/DLG5/PDLIM5/DAPK3/S100A10/EFNA5/EIF4G1/SRC/CLDN1/EPHA7/LRRN3/CAMSAP3/ACTG1/GPC4/SETD5/RAP1A/CAV1/FERMT2/SLITRK6/MMP14/SLITRK5/FLOT1/TSC1/CLSTN3
GOBP_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION 148 0.4391939 1.610830 0.0007161 0.0154076 0.0126580 2338 CCL26/ALOX15/SFRP1/CDC42EP5/MAP1B/ARHGEF5/CLASP1/CD47/CDC42EP1/APOE/EDN1/SYNPO/MET/HCK/CFL2/BIN1/OCLN/SNX9/CX3CL1/DLG1/GSN/TESK1/RAC1/COLGALT1/VASP/CTTN/ARHGEF10/WASL/WDR1/LIMK1/RHOC/S100A10/TGFBR1/TRPV4
GOBP_P38MAPK_CASCADE 47 0.5867892 1.775143 0.0007240 0.0155058 0.0127387 2507 RASGRP1/NCF1/PTPN22/GADD45G/VEGFA/XDH/MFHAS1/DUSP10/ZFP36/ZC3H12A/SPHK1/DLG1/MAPK11/BMP2/LGALS9/GADD45A/RELL1/RELL2/MAPKAPK2/CYLD
GOBP_GLYCEROPHOSPHOLIPID_BIOSYNTHETIC_PROCESS 190 0.4169839 1.565329 0.0007428 0.0157652 0.0129518 3012 CISH/SOCS1/PNPLA3/ALOX15/LPIN1/MFSD2A/PLA2G4C/ABHD4/SOCS2/LCAT/LIPH/FGF2/PLA2G4A/GPAT3/LPCAT4/FAR1/SOCS3/PISD/TMEM150A/PIGW/PTPMT1/SELENOI/PLSCR1/ITPKA/GPAT4/PGAP4/PIP4K2A/DGKQ/TAFAZZIN/ACP6/CAPN2/PIP5K1A/INPP1/PIK3C2B/PLD2/INPPL1/DGKA/PTDSS1/PITPNM2/ITPKC/TTC7A/ABHD3/ACSL3/DGKD/INPP5J/PIP4K2C
GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING 255 0.3982842 1.558393 0.0007404 0.0157652 0.0129518 3063 EDNRA/TLR4/PRKD1/NOD2/TNIP3/MAP3K14/CD36/UBD/CARD19/IL1A/EDAR/BST2/SECTM1/TICAM1/LURAP1/EDN1/RELB/NEK6/CTH/RIPK3/IRAK2/NFKBIA/LURAP1L/CARD11/TMEM106A/CANT1/TLE1/MYD88/TNF/ZC3H12A/CX3CL1/HMOX1/TNIP1/IFIT5/OPTN/PLEKHG5/LGALS9/TNFRSF19/OTUD7A/FYN/TRIM14/CARD9/SHISA5/FADD/STAT1/NDFIP2/TRIM21/IRAK1/RBCK1/RIPK2/TRAF5/TRIM25/TNFAIP3/NFKBIB/BCL10/SQSTM1/LTBR/RHOC/AKT1/RORA/IRAK4/RELA/TRIM5/MUL1/NOD1/BIRC3/BCL3/SLC20A1/DDRGK1/TRAF3IP2/AKAP13/IKBKG/IKBKE/TRIM22/TNFRSF10B/NKIRAS2
GOBP_SPECIFICATION_OF_SYMMETRY 105 -0.4526393 -1.667000 0.0007487 0.0158171 0.0129945 4170 ANKS6/CCDC40/SMO/DNAAF11/ENKUR/RTTN/IHH/ARL6/DRC1/ARL13B/TMEM107/ODAD4/DNAAF2/CCDC39/DNAI1/NOTCH1/TBC1D32/CFAP52/DYNC2LI1/FOXJ1/DPCD/IFT57/IFT140/CC2D2A/IFT52/IFT74/CITED2/ACVR2B/ODAD3/RPGRIP1L/DLL1/IFT172/DYNC2H1/DAW1/MKS1/RFX3/STIL/WNT3A/FOLR1/DNAAF1/DNAAF4/DNAI2/BBS4/CFAP45/WNT5A/BICC1/DNAH5/CFAP53/GJA1/ODAD2/SOSTDC1/ASB2/SHH/MEF2C/FOXN4
GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION 78 0.5305488 1.784160 0.0007588 0.0159175 0.0130769 2010 APOBEC3A/RSAD2/ISG15/OAS3/ISG20/OASL/OAS1/CXCL8/MX1/IFIT1/BCL2/IFITM1/IFIH1/BST2/OAS2/IFITM3/TNF/SHFL/TNIP1/IFIT5/CCL5/ADAR/PLSCR1/N4BP1/EIF2AK2/APOBEC3B/PARP10/ZNFX1
GOBP_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY 80 0.5152110 1.731209 0.0007602 0.0159175 0.0130769 3267 IL19/GDNF/BCL2/IL1A/IFI6/TMBIM1/ICAM1/TNF/CX3CL1/PEA15/HMOX1/YAP1/THBS1/ITGA6/ITGAV/EYA4/LMNA/CTTN/SCG2/TNFAIP3/AKT1/TGFBR1/RELA/RFFL/SRC/CSF2/LGALS3/SIAH2/UNC5B/PELI3/ARHGEF2/STRADB/EYA3/EYA2/HTT/SH3RF1/ZC3HC1
GOBP_O_GLYCAN_PROCESSING 38 0.6400168 1.858307 0.0007950 0.0164242 0.0134932 1720 B3GNT6/GCNT3/GALNT4/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ST3GAL4/B3GNT8
GOBP_INTRACILIARY_RETROGRADE_TRANSPORT 13 -0.7737276 -1.847026 0.0007915 0.0164242 0.0134932 3420 DYNLT2B/DYNC2I1/IFT122/IFT43/WDR19/DYNC2LI1/TTC21A/IFT140/CILK1/WDR35/DYNC2H1/TTC21B
GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS 113 0.4729121 1.670138 0.0007935 0.0164242 0.0134932 2638 NTRK1/PLA2G3/GDNF/FZD9/BDNF/ADAM8/NTRK2/BCL2/FOXQ1/CLCF1/NES/TYRO3/ARRB2/APOE/AARS1/HIF1A/CX3CL1/HMOX1/KRAS/PRKCG/AXL/SNCA/HYOU1/ZPR1/JUN/BOK/GRIK2/FOXB1/IL27RA/NRBP2/IL6ST/WFS1
GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION 354 0.3677096 1.493008 0.0008003 0.0164601 0.0135227 2887 EMILIN2/HAS2/DPP4/SOCS1/RASGRP1/SELP/THY1/ALOX15/CD274/HYAL1/VIT/PTPN22/PDCD1LG2/PLAUR/SFRP1/CD55/CD44/ADAM8/NOD2/IL4I1/PRKCQ/CD36/EBI3/RAC3/VEGFA/IL1A/UNC13D/NEDD9/FUT3/CD47/CD70/GATA3/SLC7A1/CD86/ADAM9/ANXA1/CD276/HSD17B12/HLA-DOB/TNFSF9/NFKBID/STX3/CARD11/DUSP10/IL23A/KDR/RHOD/TNF/PIEZO1/CD83/CX3CL1/LIF/IL4R/PTAFR/ZBTB7B/CCL5/ST3GAL4/LGALS9/FYN/SOX2/NR4A3/TFE3/TESK1/ITGAV/FADD/IL1RL2/TJP1/RAC1/PLEKHA2/IRAK1/EGFL6/RIPK2/CD46/TNFRSF13C/MAP3K8/IL15/GCNT2/MYO10/BCL10/FLCN/AP3D1/HLA-DQB2/RELL2/S100A10/AKT1/PODXL/RELA/ITGA3/RUNX1/PDPN/CYTH3/STX4/SRC/PTPN11/IL27RA/FERMT1/IL6ST/FUT4/ALOX5/SYK/DAG1/TRIOBP/SKAP1/CSK/CAV1/NFAT5/IGF2
GOBP_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS 421 0.3541876 1.466347 0.0008178 0.0167465 0.0137580 1940 CCL26/NTRK1/CLDN5/THY1/ALOX15/HYAL1/MMP1/TLR4/TRABD2A/WARS1/BDNF/SFRP1/ISG15/CDC42EP5/PHLDB2/HAS3/MAP1B/GBP5/ARHGEF5/LRRTM2/TENM2/NTRK2/CD36/PPP2R5B/VEGFA/EPHB3/CLASP1/CD47/CDC42EP1/TWF2/SYNPO/MET/WASHC1/HCK/DOCK11/BAK1/BIN1/BIK/CAPG/OCLN/SOX9/KDR/MYD88/TNF/SNX9/PIEZO1/VSTM5/CRB3/CX3CL1/CDK2/DLG1/EPHA2/NDEL1/ABCA3/TESK1/SNCA/SLX4/RAC1/ATP13A2/VASP/CTTN/ARHGEF10/PLCE1/PIP4K2A
GOBP_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION 492 0.3419010 1.431549 0.0008220 0.0167598 0.0137689 1738 FGL2/CCN4/SOCS1/TNFAIP6/THY1/BRINP1/TLR4/SPDEF/TRIB3/CXCL10/HOPX/RTN4R/PRTG/FOXE3/BDNF/SEMA3B/INSIG1/SFRP1/PPARG/SPRY4/PAX6/LBH/LDLR/EREG/NTRK3/HES5/CEACAM5/MAP2/VEGFA/IL1A/DDIT3/GPS2/TTPA/KLF13/G6PD/GATA3/RAP1GAP/SEMA3D/PRICKLE1/XDH/ANXA1/JDP2/ENPP1/SOX6/TRIB1/NFKBIA/NOTCH4/MSX2/DAB1/S1PR3/SOX9/CEACAM1/DUSP10/PLXNA3/TRIB2/ZFP36/SEMA7A/PKP2/TNF/ZC3H12A/ASCL1/YAP1/ID3/SEMA3A/SEMA4C/RGS2/IL4R/SPRED2/TRPM4/APPL2/BMP2/ZBTB7B/MMP11/SEMA6A/CDKN2B/MARK1/KRAS/OSR1/NOCT/SOX2/CCN3/SLIT1/GREM1/NTN1/PRDM6/SPAG9/ITGAV/RUFY3
GOBP_PEPTIDYL_TYROSINE_MODIFICATION 295 0.3827679 1.531657 0.0008342 0.0169340 0.0139120 2915 NTRK1/ADRA1A/SOCS1/THY1/NCF1/HBEGF/SFRP1/CD44/IL12RB2/NOD2/FGFR4/ALKAL1/ACE/NTRK2/FLT1/CD36/EREG/IL31RA/DOK7/NTRK3/HES5/PPP2R5B/VEGFA/NEDD9/CBLC/RELN/DOCK3/EPHB3/CLCF1/LRP8/TYRO3/ARRB2/PARP9/TTN/MET/HCK/KITLG/EPHA3/ROR2/IL23A/KDR/TNF/DDR2/SOCS3/EPHA10/LIF/EPHA2/PARP14/CCL5/FYN/ERRFI1/GREM1/PKDCC/AXL/SH2B3/RAP2B/MST1R/TESK1/ZGPAT/CAMKK2/EIF2AK2/TGFA/RIPK2/TEC/RAP2C/DGKQ/TNK2/CHMP6/IL15/GPRC5A/BMP6/PRNP/PTK6/EFNA5/ZFYVE28/ADAM17/SCYL1/GAS6/SRC/PTPN11/CSF2/EPHA7/PAK2/CADM4/IL6ST/BCR/MAP2K1/SYK/TTL/HAX1/CSK/CAV1/TESK2/IGF2/ISL1
GOBP_LEUKOCYTE_APOPTOTIC_PROCESS 84 0.5102678 1.726906 0.0008527 0.0172339 0.0141584 2389 CD274/SLC7A11/ADAM8/NOD2/PRKCQ/ST6GAL1/PIP/IDO1/IRF7/HSH2D/ANXA1/KITLG/RIPK3/BAK1/HIF1A/FAS/IRS2/ARG2/CCL5/LGALS9/PLEKHO2/AXL/FADD/PRELID1/CDKN2A/BCL10/AKT1/ADAM17/SELENOS/GAS6
GOBP_SERTOLI_CELL_DIFFERENTIATION 13 0.8200017 1.872652 0.0008724 0.0174036 0.0142978 1385 NTRK1/IL1A/SOX9/SCX
GOBP_LYMPHOCYTE_CHEMOTAXIS 35 0.6431044 1.826390 0.0008703 0.0174036 0.0142978 2533 CCL26/CXCL10/CCL4/CH25H/CXCL11/ADAM8/CCL22/CXCL16/SLC12A2/S100A7/CX3CL1/CCL5/HSD3B7/OXSR1/SLC8B1/ADAM17/GAS6/PLEC/CCL20
GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION 207 0.4016106 1.524402 0.0008797 0.0174036 0.0142978 2013 FGL2/PLA2G3/SOCS1/TNFAIP6/RASGRP1/TLR4/SLC9B2/PRDM1/SFRP1/ADAM8/PPARGC1B/IL4I1/FOS/TOX/IRF7/GATA3/CD86/ANXA1/KITLG/TNFSF9/TRIB1/NFKBID/CARD11/ROR2/CEACAM1/DUSP10/IL23A/TNF/ZC3H12A/CD83/LIF/IL4R/ZBTB7B/LGALS9/TFE3/IL15RA/AXL/SPINK5/FADD/IL1RL2/PRXL2A/RIPK2/PRELID1/CD46/IL15
GOBP_REGULATION_OF_PEPTIDASE_ACTIVITY 344 0.3660212 1.481392 0.0008758 0.0174036 0.0142978 2722 CST1/FETUB/SERPINB4/SERPINB2/SERPINB10/HMSD/SERPINC1/SERPINB13/PLAUR/SERPINB12/CD44/PPARG/KLF4/NR4A1/AIM2/F3/VEGFA/CSTA/SERPINB9/BBC3/IFI6/BST2/ARRB2/SFN/UBE2Z/PMAIP1/SERPINB8/SERPINB7/XDH/ANOS1/PI3/BAK1/TIMP2/BIN1/HIP1/LAMP3/PML/TFPI2/ANXA8/PTGS2/ITIH2/MAPK12/TNF/SERPINB6/FAS/SERPINB11/CLDN4/CSTB/NLRP2/LGALS9/THBS1/CYCS/SERPINB1/FYN/SOX2/CARD9/SOX7/SERPINB3/GSN/SPINK5/SERPINH1/SNCA/FADD/SPINT2/ANXA8L1/ATP13A2/A2ML1/RIPK2/PRELID1/AKIRIN2/SORL1/TIMP1/ST18/FURIN/PRNP/BCL10/ACER2/DHCR24/MICAL1/TBC1D10A/AKT1/BOK/MYC/NKX3-1/GPER1/GAS6/PICALM/USP14/RFFL/SRC/MUL1/NOD1/BIRC3/EPHA7/ACVR1C/BID/PAK2/DNAJB6/DDRGK1/SYK/IFI16
GOBP_MITOTIC_CELL_CYCLE_PHASE_TRANSITION 381 -0.3322029 -1.439298 0.0008793 0.0174036 0.0142978 1369 CDC7/MTBP/MELK/ADAMTS1/HSPA2/PKMYT1/ABRAXAS1/CDC25A/BLM/HECW2/STOX1/CAMK2A/FHL1/FBXO5/ANAPC4/CCNB1/ORC1/TRIP13/CCNP/CDC14A/CCNO/E2F1/FOXM1/FBXL22/E2F7/CCL2/TTK/CIT/CDT1/CDCA5/CDKN3/NDC80/KIF14/MAD2L1/CENPF/CCNB2/CENPE/CCNE2/PLK1/TICRR/CDK1/IQGAP3/ANLN/RRM2/DTL/BUB1/GTSE1/DLGAP5/CDC25C/UBE2C/BUB1B
GOBP_ALCOHOL_METABOLIC_PROCESS 283 0.3835913 1.527957 0.0009042 0.0178137 0.0146347 2869 CYP51A1/MVD/HMGCS1/EBP/FDPS/LSS/PCSK9/DHCR7/MSMO1/ACSS2/HMGCR/INSIG1/CH25H/PCK2/ADH1C/HSD17B7/IDI1/LRAT/LDLR/ALDH1A3/FDFT1/NPC1/HRH1/SQLE/NSDHL/ACLY/SC5D/NFE2L1/LCAT/FGF2/G6PD/RDH11/SRD5A3/APOE/TM7SF2/PLA2G4A/GOT1/CYP27B1/MVK/P2RY1/SLC5A3/SDR16C5/SCARB1/DHRS7/IDH1/CYP2C18/APOL2/CYP46A1/SPHK1/RETSAT/GCH1/PTAFR/GPD2/BMP2/TPK1/SREBF2/APOBR/CYP2C9/APOL1/ACADL/P2RY6/GBA2/SNCA/SGPP2/RDH13/ITPKA/CYP3A5/DGKQ/GALK1/DHDDS/GDPD3/BMP6/ACER2/DHCR24/INPP1/ITPK1/ASAH2/CYB5R3/GPER1/SGPP1/OSBPL1A/GFI1/CLN6/PIP4P1/ITPKC/PPARD/SPTSSA/PTS/AKR1A1/OSBPL5/SMPD1/ACER3/ALDH3B2/NPC2/IPPK
GOBP_VENTRICULAR_CARDIAC_MUSCLE_CELL_DIFFERENTIATION 11 -0.7890329 -1.794024 0.0009094 0.0178411 0.0146572 755 HEY2/MEF2C/CDK1/MYOCD
GOBP_MEIOSIS_II_CELL_CYCLE_PROCESS 10 -0.8133215 -1.804383 0.0009188 0.0178862 0.0146943 479 HORMAD1/SGO2/SGO1/BUB1/BUB1B
GOBP_PROTEIN_AUTOPHOSPHORYLATION 199 0.4130104 1.563885 0.0009232 0.0178862 0.0146943 2870 NTRK1/THY1/GRK5/PRKD1/FGFR4/STK10/ACE/NTRK2/FLT1/MAPKAPK3/PPP2R5B/VEGFA/TNIK/EPHB3/DAPK2/TYRO3/NEK6/ENPP1/HCK/GRK7/RIPK3/SLK/MKNK1/KDR/UHMK1/DDR2/STK17B/ENG/FYN/ERRFI1/GREM1/PRKCG/PIM1/RAP2B/TESK1/OXSR1/CAMKK2/EIF2AK2/IRAK1/ATP13A2/MAP3K9/TEC/TNKS1BP1/RAP2C/MAP3K21/PIM3/PTK6/DAPK3/AAK1/AKT1/JUN/CHP1/MAPKAPK2/SRC/EPHA7/PAK2/STK25/TAOK3/SYK/EIF2AK3/CSK/CAV1/MAP3K13
GOBP_REGULATION_OF_VASCULATURE_DEVELOPMENT 218 0.4056390 1.553236 0.0009216 0.0178862 0.0146943 1944 CLDN5/EMILIN2/HYAL1/ADM2/WARS1/CXCL10/PRKD1/PPP1R16B/SFRP1/PPARG/KLF4/YJEFN3/CXCL8/FLT1/AMOT/F3/HHEX/VEGFA/KLF2/IL1A/SLC12A2/FGF2/TNFSF12/SMOC2/ANXA3/HK2/CCR3/BTG1/HIF1A/PML/CEACAM1/ITGB8/KDR/SARS1/TNF/ZC3H12A/NIBAN2/SULF1/ADAMTS9/HMOX1/SPHK1/EPHA2/ENG/SEMA6A/THBS1/GADD45A/GREM1/STIM1/SPINK5/TJP1/STAT1/AKT3/RHOB/TNFAIP3
GOBP_NEURON_PROJECTION_GUIDANCE 176 0.4377189 1.630017 0.0009333 0.0180071 0.0147936 1885 NTRK1/GDNF/LGR6/EDNRA/DLX5/PTPRO/BDNF/SEMA3B/CRMP1/PAX6/BCL11B/FOXD1/SLIT2/PRKCQ/ARTN/VEGFA/RELN/EPHB3/GATA3/SEMA3D/TUBB3/EDN1/EGR2/ANOS1/EPHA3/NRP2/PLXNA3/SEMA7A/NRCAM/NIBAN2/EPHA10/SEMA3A/SEMA4C/ECE1/EPHA2/SEMA6A/FYN/RHOG/SLIT1/NTN1/DPYSL2/IGSF9/RAC1/KIF5C/VASP
GOBP_ACTIN_FILAMENT_ORGANIZATION 379 0.3609575 1.472185 0.0009421 0.0181023 0.0148719 2987 CCL26/ALOX15/SFRP1/CTNNA3/CDC42EP5/PHLDB2/PPARGC1B/ARHGEF5/SLIT2/RAC3/BCL2/TMOD1/NEDD9/CLASP1/CD47/CDC42EP1/ARHGAP40/PHACTR1/PLS1/TWF2/MYO1A/SYNPO/TTN/MET/WASHC1/HCK/CFL2/ZBED3/SPATC1L/SHROOM1/BIN1/HIP1/ASAP3/CAPG/ESAM/NAA80/RHOD/TMSB10/SNX9/FLII/MYO1C/SPIRE1/CX3CL1/DBN1/SVIL/MSRB1/DLG1/TNFAIP1/RND3/BCAR1/RHOG/MYO5B/SLC9A1/GSN/ARPC5L/SSH1/TESK1/GBA2/RUFY3/TJP1/MICAL2/RAC1/PSTPIP2/MYO5C/VASP/CTTN/ARHGEF10/RHOB/KANK3/WASL/TPM3/WDR1/MCU/MYO1E/FHDC1/ERMN/SPTBN5/MICAL1/MYO19/LIMK1/RHOC/PAWR/S100A10/MYO1B/SH3BP1/TGFBR1/TMSB4X/TRPV4/INPPL1/PPP1R9A/GAS2L1/SHANK3/DIAPH1/TPM4/TACSTD2/PLEC/ACTN1/SRC/PAK2/SHTN1/ACTG1/CFL1/COBL/KPTN/ARPC4/HAX1/TRIOBP/TMOD2/PPFIA1/RND1/PFN1/ELMO2/FERMT2
GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION 73 0.5246851 1.735923 0.0009628 0.0184238 0.0151360 1477 SOCS1/CDH26/CD274/LGALS7B/RSAD2/CD55/PRKCQ/TOX/GATA3/CD86/RELB/ANXA1/IL18R1/NFKBID/IL23A/ZC3H12A/CD83/ARG2/IL4R/ZBTB7B/LGALS9
GOBP_KERATINOCYTE_DIFFERENTIATION 101 0.4983136 1.736078 0.0009726 0.0184602 0.0151658 1629 SPRR2E/SPRR3/SPRR2F/SPRR2A/KRT16/SPRR1A/ZBED2/PAX6/SPRR2D/BCL11B/EREG/TRIM16/ALOX15B/CSTA/IL1A/SFN/ADAM9/CLIC4/CYP27B1/ANXA1/FOSL2/LCE1E/S100A7/MSX2/ZFP36/CDH3/YAP1/EPHA2/PRKCH/ERRFI1/IRF6
GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY 299 0.3729508 1.489430 0.0009697 0.0184602 0.0151658 2857 THY1/TLR4/PTPN22/RSAD2/THEMIS2/LAT2/OAS3/NOD2/TNIP3/OASL/OAS1/PRKCQ/CD36/IFI35/MAPKAPK3/BCL2/IFIH1/CMTM3/DDX60/GPS2/CD47/IRF7/GATA3/TYRO3/ARRB2/UFD1/TICAM1/CD276/NECTIN2/HCK/CD200R1/LY96/MFHAS1/NFKBID/IRAK2/NFKBIA/CARD11/CEACAM1/MYD88/TNF/ZC3H12A/DUSP3/TNIP1/SLC15A3/APPL2/PRKCH/LGALS9/BCAR1/FYN/NR4A3/RNF125/PDE4B/MICB/PLSCR1/IRAK1/RBCK1/RIPK2/IL20RB/TRIM25/NPLOC4/TEC/TNFAIP3/SEC14L1/RAB29/PRNP/BCL10/LIMK1/GBP1/PAWR/PLD2/IRAK4/MAPKAPK2/RELA/GFI1/CYLD/SRC/NOD1/BIRC3/PAK2/CLPB/LGALS3/S100A14/SYK/SLC15A4/VAV2/SKAP1/CSK/CAV1/IKBKG
GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY 99 0.5015003 1.740928 0.0009914 0.0187398 0.0153955 1199 SH2D1B/NOS2/RASGRP1/RSAD2/CD55/NOD2/PVR/RAET1G/FZD5/CLCF1/GATA3/TNFSF13/TICAM1/RAET1E/NECTIN2/IL18R1/ARID5A/IL23A/TNF
GOBP_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION 31 -0.6356850 -1.861692 0.0010153 0.0191152 0.0157040 3458 H4C5/SCIN/H4C12/H4C6/H4C3/H4C2/H4C4/H4C1/HMGB2/RAB7B/MTURN/FAXDC2/H4C13/H4C9/MEF2C/GATA2
GOBP_REGULATION_OF_CILIUM_MOVEMENT 25 -0.6697014 -1.885113 0.0010571 0.0197443 0.0162208 4151 CCDC40/CFAP298/DRC1/CFAP20/RSPH4A/CCDC39/BBS2/CCDC65/GAS2L2/CFAP69/DNAAF1/BBS4/CFAP43/CFAP45/CFAP206/TTLL6/ODAD2/EPPIN
GOBP_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE 101 0.4965973 1.730098 0.0010572 0.0197443 0.0162208 2923 SH2D1B/RASGRP1/ZBP1/TLR4/ADAM8/NOD2/GBP5/NLRC5/PVR/RAET1G/EREG/IFI35/AIM2/IRF7/PARP9/RAET1E/NECTIN2/HCK/CCL5/FYN/CARD9/FADD/PLSCR1/AKIRIN2/ZNFX1/HLA-F/POLR3D/TRIM5/CGAS/SRC/PAK2/SYK/IFI16/SLC15A4/IKBKE/HEXIM1
GOBP_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY 54 0.5723169 1.775235 0.0010670 0.0198311 0.0162921 2740 TLR4/PTPN22/OAS3/NOD2/OASL/IFIH1/DDX60/IRF7/UFD1/NFKBIA/SLC15A3/RNF125/RIPK2/TRIM25/NPLOC4/TNFAIP3/SEC14L1/RELA/CYLD/BIRC3/CLPB/SLC15A4
GOBP_BLOOD_VESSEL_MORPHOGENESIS 487 0.3378596 1.415666 0.0010703 0.0198311 0.0162921 1944 CLDN5/EMILIN2/HAS2/THY1/EDNRA/HYAL1/ADM2/WARS1/THSD7A/CXCL10/PRKD1/PPP1R16B/PRDM1/SFRP1/ADAM8/PPARG/FAP/KLF4/FGFBP1/LDLR/ACE/YJEFN3/ANPEP/NR4A1/SLIT2/CXCL8/NTRK2/FLT1/EREG/DLL4/AMOT/HDAC9/F3/MMP19/HHEX/VEGFA/KLF2/IL1A/FZD5/SLC12A2/FGF2/EPHB3/TNFSF12/SMOC2/ANXA3/APOE/EDN1/HPGD/TNFRSF12A/HK2/XDH/CLIC4/ANXA1/CCR3/BTG1/BAK1/NOTCH4/S100A7/NRP2/PLCD3/HIF1A/PML/CEACAM1/PTGS2/ITGB8/KDR/SARS1/TNF/ZC3H12A/NRCAM/NIBAN2/SULF1/ADAMTS9/CX3CL1/RNF213/HMOX1/CALCRL/YAP1/SPHK1/EPHA2/ENG/SEMA6A/THBS1/COL22A1/GADD45A/CCN3/GREM1/LOX/CCM2/STIM1/SPINK5/ITGAV/TJP1/STAT1/AKT3/TGFA/TYMP/MYH9/RHOB/SCG2/JUNB/TNFAIP3
GOBP_ENDOCYTIC_RECYCLING 69 0.5277420 1.727661 0.0010781 0.0198958 0.0163453 4335 PLA2G3/ARL4C/EHD3/WASHC1/GRIP2/NDRG4/EHD1/SORL1/EIPR1/SCRIB/RAB35/VPS26C/EPS15/GGA3/CCDC93/EHD2/MICALL1/INPP5F/LMTK2/PTPN23/WASHC2C/SNF8/RAB8A/RAB11A/GRIPAP1/VPS35L/SNX12/ANKRD27/ARF6/EHD4/RAB7A/GRIP1/RAB14/VPS29/DENND1A/VPS26A
GOBP_MONONUCLEAR_CELL_MIGRATION 129 0.4631613 1.663043 0.0011150 0.0204717 0.0168184 2705 CCL26/PTPRO/CXCL10/CCL4/CH25H/CXCL11/ADAM8/ARHGEF5/STK10/SLIT2/CCL22/FLT1/ARTN/CXCL16/SLC12A2/CD47/GATA3/PLA2G7/ANXA1/CD200R1/RIPK3/S100A7/ICAM1/TNF/CX3CL1/TRPM4/CCL5/HSD3B7/LGALS9/THBS1/CCN3/GREM1/OXSR1/FADD/SLC8B1/WASL/ITGB7/AKT1/MSN/ADAM17/TRPV4/GAS6/PLEC/CCL20/IL27RA/MIA3/LGALS3/FUT4/ALOX5/S100A14
GOBP_EPITHELIAL_CELL_PROLIFERATION 329 0.3647105 1.469407 0.0011225 0.0204717 0.0168184 1944 CCL26/HAS2/DLX5/LGR5/HYAL1/PRKD1/FOXE3/PPP1R16B/SFRP1/PPARG/FAP/NOD2/PAX6/FGFBP1/BCL11B/NR4A1/FLT1/EREG/DLL4/HES5/F3/VEGFA/FGF2/TNFSF12/GATA3/RAP1GAP/APOE/SFN/XDH/CCR3/SDR16C5/CDKN1C/EPPK1/KLF9/SCARB1/NRP2/HIF1A/SOX9/CEACAM1/DUSP10/ZFP36/KDR/TNF/CDH3/SULF1/CAV2/HMOX1/YAP1/DLG1/EPHA2/BMP2/FUT2/CDKN2B/THBS1/OSR1/SERPINB1/SOX2/ERRFI1/CCN3/NR4A3/IRF6/STAT1/SGPP2/VDR/AKT3/TGFA/MARVELD3/EHF/SCG2/TNFAIP3
GOBP_GAMETE_GENERATION 493 -0.3087734 -1.358500 0.0011224 0.0204717 0.0168184 2474 PAQR7/SYNE1/FOXJ1/HORMAD1/DPCD/SPEF2/LRRK2/TTC21A/MYCBP/ZSCAN2/CFAP58/ROPN1L/NDC1/CFAP69/IFT27/CFAP91/PCSK4/CREB3L4/DRC7/INPP5B/SPAG16/SPINK1/CFAP47/SPA17/TTC12/NPHP1/ERCC1/RFX2/DNAH1/CETN2/IFT81/HSF2/TSPAN8/SIX5/SLC26A8/IQCG/TDRP/RACGAP1/NME5/CCDC136/RSPH1/SPATA32/TCFL5/BMPR1B/CFAP44/SPOCD1/HOOK1/IFTAP/FOXL2/TDRD6/PTK2B/CFAP65/TESMIN/NANOS1/GAS2/GAMT/BBS4/MNS1/HOATZ/CFAP43/ROS1/ADAMTS1/MCM8/KIF18A/TSGA10/CFAP206/ZCWPW1/HSPA2/CCDC87/PMFBP1/M1AP/GDF9/SPATA9/BRIP1/HMGB2/PLAT/FBXO5/FMN2/SPAG4/PIWIL2/HROB/HSF2BP/TRIP13/GJA1/PTN/ELL3/KIT/MEIG1/PTTG1/NEURL1/YBX2/KNL1/BMP15/E2F1/MGAT4D/MYBL1/TTK/OCA2/NDC80/MYCBPAP/BCL2L10/H1-1/CCNB2/NCAPH/ASF1B/TSSK3/PLK1/CYP26B1/AR/CATSPERD/NLRP14/DMC1/ZBTB16/CDC25C/ASPM/TOP2A/CNTD1
GOBP_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT 32 0.6533819 1.847479 0.0011398 0.0207065 0.0170113 1361 NTRK1/GDNF/EDNRA/GATA3/EGR2/KIF26A/NRP2/PLXNA3/ASCL1/SEMA3A
GOBP_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION 438 0.3391205 1.407613 0.0011572 0.0209418 0.0172046 3475 NTRK1/ADRA1A/RASGRP1/PRKD1/RTN4R/RAB42/CDC42EP5/SPRY4/USP28/ARHGAP31/ARHGEF5/SLIT2/DENND4A/ARHGAP30/AMOT/RAC3/ARHGAP11B/ARHGAP21/RELN/DOCK3/FGF2/CDC42EP1/RTKN/RAP1GAP/ARHGAP40/APOE/DOK1/FBP1/MET/KITLG/FGD2/DOCK11/PRAG1/GMIP/DAB1/TAGAP/PLEKHG6/RHOD/HMOX1/RIPOR1/CDK2/FGD3/LRRC59/TNFAIP1/RND3/PLEKHG1/ARHGAP27/PLEKHG5/KRAS/RHOG/RRAGC/RAB15/CDC42SE1/NTN1/RAP2B/RASA2/ITGAV/ARHGDIA/SIPA1L2/RAC1/RAB4B/RAP1GAP2/RAB9A/PSD4/ARHGEF10/RHOB/PLCE1/RAP2C/STMN3/TNK2/RASIP1/CDKN2A/CHN1/NRAS/ARHGAP10/FLCN/SQSTM1/CDKN1A/DHCR24/RAB35/RASSF1/LIMK1/GNA12/RHOC/DENND3/JUN/PLD2/SH3BP1/DENND4C/NGEF/CHP1/RANGRF/ITGA3/PDPN/MCF2/CYTH3/EPS8L1/SRC/RRAS2/RAPGEF4/ARHGAP8/MAPRE2/SHTN1/CADM4/BCR/RABIF/RGS19/RALA/CFL1/TIAM1/VAV2/TIAM2/RAP1A/AKAP13/DOCK7/RND1/GNB1/SIAH2/MFN2/CRK/SIPA1L1/CBL/DOCK6/GBF1/MYO9B/ARHGEF2/NKIRAS2/FLOT1/WASF1/SWAP70/RREB1/ARHGAP17/ERBIN/HEG1/GARRE1/PLEKHG3/PHACTR4/RASAL1/PLK2/SH2D3C/ABR/TP53/DOCK5/RHOT2/SPRY2/ARHGEF1/LZTR1/ARFGAP1/KALRN/CYRIB
GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_HOST 157 0.4282660 1.571134 0.0011673 0.0210431 0.0172878 3358 CH25H/CD55/LDLR/ANPEP/NPC1/CXCL8/PVR/IFIT1/SLC3A2/IFITM1/TYRO3/CD86/SLC1A5/KRT6A/NECTIN2/TMPRSS2/SCARB1/LAMP3/VPS37B/IFITM3/ICAM1/RNASEK/CAV2/EPHA2/LGALS9/TRIM14/SERPINB3/GSN/AXL/SLC52A2/ITGAV/TPCN2/PLSCR1/TRIM21/TRIM25/CLDN9/CD46/NECTIN4/CHMP6/ITGB7/ITGB6/CHMP7/FCN3/GAS6/SLC20A2/TMPRSS4/TRIM5/SRC/CLDN1/EPS15/DAG1/SMPD1/THOC6/CAV1/TRIM22/CBL/VPS4A/VPS4B/CHMP1B/TFRC/P4HB/CD81/ATG7
GOBP_OUTER_DYNEIN_ARM_ASSEMBLY 19 -0.7031302 -1.841911 0.0011727 0.0210583 0.0173003 3518 ODAD1/DNAAF11/ZMYND10/ODAD4/DNAAF2/DNAI1/DNAL1/ODAD3/DAW1/DNAAF1/DNAAF4/DNAI2/LRRC49/DNAH5/DNAAF6/DNAAF8/ODAD2
GOBP_REGULATION_OF_P38MAPK_CASCADE 37 0.6300980 1.804356 0.0011947 0.0213715 0.0175576 1525 RASGRP1/NCF1/PTPN22/GADD45G/VEGFA/XDH/MFHAS1/DUSP10/ZC3H12A/SPHK1/DLG1/BMP2/LGALS9/GADD45A
GOBP_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS 26 0.7103726 1.924691 0.0012028 0.0214343 0.0176092 2035 IDO2/PSAT1/SLC5A8/NNMT/HAAO/IDO1/PARP9/QPRT/NAMPT/KYNU/NADK/PARP10/PDXK
GOBP_GLYCEROLIPID_CATABOLIC_PROCESS 49 0.5881757 1.784613 0.0012401 0.0220150 0.0180863 1025 PNPLA3/APOC1/AADAC/LIPG/LDLR/PLA2G4C/ENPP6/PNPLA1/LIPH/PLA2G7/PLA2G4A/GPCPD1/SCARB1
GOBP_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS 23 0.6949942 1.822445 0.0012518 0.0221381 0.0181874 1987 IDO2/SLC5A8/NNMT/HAAO/IDO1/PARP9/QPRT/NAMPT/KYNU/NADK/PARP10
GOBP_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION 78 0.5169673 1.738487 0.0012696 0.0223681 0.0183763 1899 CCL26/ALOX15/CDC42EP5/MAP1B/CLASP1/CDC42EP1/MET/HCK/BIN1/OCLN/SNX9/DLG1/RAC1/VASP/CTTN
GOBP_VIRAL_GENOME_REPLICATION 117 0.4665056 1.653806 0.0013085 0.0229681 0.0188693 3085 APOBEC3A/RSAD2/ISG15/OAS3/ISG20/OASL/OAS1/CXCL8/MX1/IFIT1/BCL2/IFITM1/IFIH1/STOM/BST2/IFI27/OAS2/IFITM3/TNF/ZC3H12A/SHFL/TNIP1/IFIT5/CCL5/ADAR/PLSCR1/N4BP1/EIF2AK2/APOBEC3B/PARP10/ZNFX1/RAB29/PCBP1/GAS6/TMEM41B/PDE12/IFI16/LARP1/TBC1D20/CCNK/SRPK1/PKN2/RAD23A
GOBP_REGULATION_OF_LYMPHOCYTE_ACTIVATION 335 0.3624499 1.461897 0.0013176 0.0230409 0.0189291 2322 FGL2/DPP4/SOCS1/RASGRP1/THY1/CD274/LGALS7B/TLR4/PTPN22/PDCD1LG2/PRDM1/SFRP1/CD55/ADAM8/THEMIS2/NOD2/IL4I1/PRKCQ/EBI3/IDO1/BCL2/IL1A/TOX/CLCF1/CD47/CD70/GATA3/SLC7A1/TYRO3/TNFSF13/TICAM1/CD86/MICA/ANXA1/CD276/HLA-DOB/TNFSF9/RIPK3/NFKBID/CARD11/CEACAM1/DUSP10/IL23A/MYD88/ZC3H12A/AHR/DUSP3/CD83/IRS2/ARG2/IL4R/DLG1/ZBTB7B/CCL5/LGALS9/FYN/IL15RA/AXL/SPINK5/FADD/IL1RL2/RIPK2/IL20RB/PRELID1/TNFAIP3/CD46/TNFRSF13C/MAP3K8/IL15/SHLD2/PRNP/BCL10/CDKN1A/DLG5/SCRIB/AP3D1/HLA-DQB2/PAWR/AKT1/HLA-F
GOBP_NEGATIVE_REGULATION_OF_PROTEOLYSIS 243 0.3935094 1.534134 0.0013288 0.0231501 0.0190188 2657 CST1/FETUB/IL1R2/SERPINB4/SERPINB2/SERPINB10/CHAC1/HMSD/SERPINC1/SERPINB13/PLAUR/SERPINB12/CD44/KLF4/NR4A1/VEGFA/CSTA/SERPINB9/IFI6/BST2/ARRB2/SFN/UBE2Z/SERPINB8/SERPINB7/ANOS1/PI3/TIMP2/BIN1/LAMP3/PML/TFPI2/ANXA8/PTGS2/ITIH2/TNF/SERPINB6/SERPINB11/CSTB/THBS1/SERPINB1/PRKCG/SERPINB3/SPINK5/SERPINH1/SNCA/SPINT2/ANXA8L1/TRIM21/N4BP1/A2ML1/HDAC6/SORL1/TIMP1/FURIN/PRNP/DHCR24/MICAL1/AKT1/GAS6/PICALM/USP14/RFFL/F8A1/SRC/BIRC3/GIPC1/PAK2/DNAJB6/DDRGK1
GOBP_FAT_CELL_DIFFERENTIATION 189 0.4067439 1.525234 0.0013340 0.0231536 0.0190217 2791 CCN4/SOCS1/PNPLA3/GRK5/TRIB3/INSIG1/SFRP1/PPARG/KLF4/NR4A1/ALOXE3/PTPRQ/DDIT3/GPS2/GATA3/EGR2/JDP2/ENPP1/MSX2/METRNL/DUSP10/PTGS2/TRIB2/ZFP36/TNF/ZC3H12A/WDFY2/ARID5B/YAP1/LRRC8C/RGS2/TRPM4/BMP2/ZBTB7B/MMP11/NOCT/NR4A3/PIM1/CCDC71L/TFE3/LAMB3/ARL4A/HDAC6/ZBTB7C/TMEM120A/FLCN/AKT1/RORA/TRPV4/AXIN1/GPER1/TMEM120B/KLF5/PPARD/ALOX5/ATF5/PPARGC1A/SIRT2
GOBP_NERVE_GROWTH_FACTOR_SIGNALING_PATHWAY 10 0.8273984 1.779352 0.0013445 0.0231923 0.0190535 240 NTRK1/BDNF
GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE 138 0.4519239 1.642572 0.0013531 0.0231923 0.0190535 2046 ALOX15/CD274/IL1RL1/RSAD2/CD55/NOD2/IL4I1/PVR/PRKCQ/FZD5/ADCY7/CLCF1/IRF7/GATA3/TNFSF13/PLA2G4A/ANXA1/NECTIN2/IL18R1/RIPK3/NFKBID/ARID5A/CEACAM1/DUSP10/IL23A/TNF/ZC3H12A/AHR/IL4R/TRPM4/ZBTB7B/NLRP10/CARD9/FADD/RIPK2/IL20RB/TNFAIP3/CD46/SHLD2
GOBP_LEUKOCYTE_CHEMOTAXIS 159 0.4302110 1.590251 0.0013512 0.0231923 0.0190535 1831 CCL26/DPP4/TNFAIP6/PTPRO/CXCL10/CCL4/CH25H/CXCL11/ADAM8/NOD2/CXCL9/ARHGEF5/HRH1/SLIT2/CXCL8/CCL22/FLT1/CXCL16/VEGFA/SLC12A2/DAPK2/PLA2G7/EDN1/ANXA1/S100A7/CXCL1/IL23A/CAMK1D/CX3CL1/ITGA9/TRPM4/CCL5/HSD3B7/LGALS9/THBS1/CXCL2/CCN3/GREM1/MMP28/OXSR1/PDE4B/CXCL6/RAC1/SLC8B1
GOBP_EPITHELIAL_CELL_DEVELOPMENT 175 0.4204217 1.561785 0.0013561 0.0231923 0.0190535 2809 NTRK1/CLDN5/EDNRA/SPDEF/PPP1R16B/PRDM1/PAX6/BCL11B/VEGFA/TMOD1/IL1A/FASN/SFN/MET/ATF4/CLIC4/FOSL2/NOTCH4/HIF1A/S1PR3/VCL/SOX9/MYD88/ICAM1/TNF/YAP1/EPHA2/COL22A1/CCM2/RAP2B/SLC9A4/PLOD3/TJP1/SPINT2/ACTA2/VSIG1/GPAT4/RAP2C/E2F4/BMP6/MYO1E/TJP2/AKT1/PODXL/MSN/PLEC/SRC/CLDN1/KLF5/TIGAR/IL6ST/C1GALT1/TBC1D20/LAMB2/RAP1A
GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION 205 0.4025435 1.526760 0.0013825 0.0235576 0.0193536 2581 IL1R2/CD274/LGALS7B/TLR4/PTPN22/PDCD1LG2/IL1RL1/OAS3/NOD2/KLF4/OAS1/HOMER2/HDAC9/IDO1/KLF2/DDIT3/ADCY7/GATA3/BST2/ARRB2/UFD1/RELB/ANXA1/CD200R1/PML/CEACAM1/TRIB2/IL23A/ZFP36/SARS1/TNF/ZC3H12A/CDH3/CD83/CX3CL1/SYT11/HMOX1/RPS6KA4/ARG2/EPHA2/APPL2/LGALS9/THBS1/SERPINB1/ERRFI1/RNF125/AXL/ANXA4/RAC1/N4BP1/IL20RB/NPLOC4/TNFAIP3/HOMER3/FURIN/PRNP/GBP1/TMSB4X/HLA-F/SELENOS/GAS6/CYLD/HDAC7/MUL1/CPTP/IL27RA/BCL3
GOBP_LEUKOCYTE_MIGRATION 269 0.3868252 1.526226 0.0013978 0.0237329 0.0194977 2711 CCL26/DPP4/TNFAIP6/SELP/THY1/PTPRO/SELL/CXCL10/CCL4/CH25H/CXCL11/ADAM8/NOD2/CXCL9/ARHGEF5/STK10/HRH1/SLIT2/CXCL8/CCL22/FLT1/ARTN/CXCL16/VEGFA/IL1A/SLC12A2/DAPK2/CD47/GATA3/PLA2G7/EDN1/CD9/ANXA1/HCK/CD200R1/KITLG/RIPK3/S100A7/ROR2/CXCL1/IL23A/MYD88/ICAM1/TNF/CAMK1D/CX3CL1/ITGA9/HMOX1/PTAFR/TRPM4/CCL5/HSD3B7/ST3GAL4/LGALS9/THBS1/FYN/RHOG/CXCL2/CCN3/GREM1/ITGA6/MMP28/P2RX4/OXSR1/PDE4B/FADD/CXCL6/RAC1/SLC8B1/MYH9/SCG2/WASL/ITGB7/SBDS/WDR1/MCU/AKT1/MSN/MTUS1/ADAM17/TRPV4/IRAK4/PF4V1/GAS6/CD177/ITGA3/PLEC/SRC/CCL20/IL27RA/MIA3/BCR/LGALS3/FUT4/ALOX5/S100A14/SYK
GOBP_REGULATION_OF_BODY_FLUID_LEVELS 290 0.3770198 1.502353 0.0014086 0.0238293 0.0195768 2543 ADRA2C/EMILIN2/HAS2/C1QTNF1/VWF/SELP/NFE2/SERPINB2/STATH/TLR4/PROCR/PTPRO/KRT16/SLC7A11/SERPINC1/PLAUR/FAP/PRKCQ/CD36/ALOXE3/FA2H/F3/VEGFA/SOCS2/SLC29A2/PLAU/GRHL3/TYRO3/APOE/SFN/EDN1/PLA2G4A/MET/CD9/HK2/XDH/P2RY1/OAS2/THBD/HIF1A/VCL/PEAR1/TFPI2/ANXA8/CEACAM1/CLDN4/ZBTB7B/ST3GAL4/ELOVL1/THBS1/MYO5B/LSR/AXL/SH2B3/RAP2B/ENTPD2/PLSCR1/VDR/MYH9/DGKI/GPAT4/TEC/DGKQ/ACTB/CSRP1/GNA12/ITPK1/TRPV4/DGKA/UBASH3B/PF4V1/GAS6/FOXB1/GRHL1/PDPN/TMPRSS11F/PLEC/ACTN1/SRC/CLDN1
GOBP_CELL_KILLING 103 0.4756511 1.663204 0.0014189 0.0238940 0.0196300 1835 NOS2/RASGRP1/SERPINB4/DEFB4A/CTSC/CD55/ULBP1/PVR/RAET1G/SERPINB9/UNC13D/ARRB2/MICA/RAET1E/NECTIN2/ULBP2/RIPK3/CEACAM1/IL23A/MYD88/ICAM1/CEBPG/LGALS9/ITGAM/RNF19B/TUBB/FADD/CXCL6/ULBP3
GOBP_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING 113 0.4612259 1.628867 0.0014278 0.0238940 0.0196300 1199 NTRK1/RASGRP1/SELP/NCF1/PPP1R16B/NYAP1/NTRK2/FLT1/NTRK3/RELN/FGF2/GATA3/TYRO3/EDN1/PEAR1/SOX9/ROR2/CEACAM1/KDR/TNF
GOBP_REGULATION_OF_MITOTIC_CELL_CYCLE 408 -0.3229746 -1.396949 0.0014238 0.0238940 0.0196300 1369 CDC7/STK33/MTBP/INSR/ADAMTS1/HSPA2/PKMYT1/ABRAXAS1/CDC25A/BLM/HECW2/CCDC8/STOX1/FHL1/FBXO5/ANAPC4/CCNB1/ORC1/GAS1/TRIP13/EPGN/CDC14A/MCIDAS/KIF20B/E2F1/E2F7/CCL2/TTK/CDT1/CDCA5/GMNN/NDC80/KIF14/FBXO43/MAD2L1/CENPF/CDCA2/CENPE/NEK2/PLK1/TICRR/CDK1/ANLN/RRM2/DTL/BUB1/GTSE1/DLGAP5/CDC25C/UBE2C/BUB1B/MKI67
GOBP_NEGATIVE_REGULATION_OF_PHOSPHORYLATION 324 0.3647374 1.468952 0.0014447 0.0240904 0.0197914 3368 SOCS1/THY1/PTPN22/PTPRO/TRIB3/WARS1/HMGCR/SFRP1/PPARG/SPRY4/PAX6/SLIT2/PTPRQ/UCHL1/NTRK3/PTPRH/HHEX/CBLC/ARRB2/APOE/SFN/FBP1/XDH/GRB10/WASHC1/ENPP1/ZBED3/CDKN1C/TRIB1/BAK1/OCLN/CEACAM1/DUSP10/TRIB2/MLXIPL/ZC3H12A/NIBAN1/PPP1R15B/RUBCN/SOCS3/DUSP3/IRS2/DBNDD1/RGS2/DUSP7/SPRED2/PARP14/BMP2/ENG/CDKN2B/GADD45A/ERRFI1/GREM1/DUSP6/SERPINB3/SH2B3/TESK1/SPAG9/SNCA/ADAR/ZGPAT/SLC8A1/ANKLE2/PIP4K2A/TNFAIP3/DGKQ/LATS2/CHMP6/SORL1/RASIP1/GPRC5A/CDKN2A/CNKSR3/PRNP/CDKN1A/PTK6/MICAL1/AKT1/KAT2B/JUN/PPP4R2/ZFYVE28/UBASH3B/EIF4G1/CHP1/PIK3IP1/PLEC/DBNDD2/TIGAR/PAK2/CADM4/YWHAG/SIRT2/SMPD1/CSK/CAV1/MIDN/AIDA/HEXIM1/PRKAR1B/SIRT6/INPP5J/CBL/SMCR8/PIP4K2C/LRRK1/PKIA/HEG1/INPP5F/GIT1/SPRED1/IBTK/MYADM/NCOR1/UBE2B/PDE4D
GOBP_CHLORIDE_TRANSMEMBRANE_TRANSPORT 43 0.6026443 1.785986 0.0014784 0.0245248 0.0201482 1617 ANO1/GABRA4/SLC26A4/SLC26A9/SLC5A1/ANO2/CLIC2/ANO4/SLC12A2/LRRC8A/SLC26A6/CLCN6/ANO7/SLC12A4/APOL1
GOBP_PROGRAMMED_CELL_DEATH_INVOLVED_IN_CELL_DEVELOPMENT 11 0.8080444 1.782430 0.0014813 0.0245248 0.0201482 920 NTRK1/BCL2/IL1A/FGF2/KITLG
GOBP_INNER_DYNEIN_ARM_ASSEMBLY 16 -0.7241531 -1.826602 0.0015120 0.0248918 0.0204497 4151 CCDC40/CFAP100/DNAAF11/ZMYND10/DNAI3/DNAAF2/CCDC39/DNAH7/TEKT2/DNAH1/CFAP73/DNAAF1/DNAAF4/DNAH2/DNAAF6
GOBP_NEGATIVE_REGULATION_OF_NEURON_DEATH 165 0.4275584 1.575302 0.0015194 0.0248918 0.0204497 3017 NTRK1/PLA2G3/GDNF/FZD9/SLC7A11/BDNF/ADAM8/NTRK2/BCL2/FOXQ1/CLCF1/NES/TYRO3/ARRB2/APOE/AARS1/ATF4/CD200R1/HIF1A/FZD1/CX3CL1/HMOX1/AP2B1/KRAS/NR4A3/PRKCG/AXL/SNCA/ATP13A2/HYOU1/ZPR1/SORL1/AKT1/JUN/BOK/HLA-F/GRIK2/EIF4G1/FOXB1/IL27RA/TIGAR/NRBP2/IL6ST/WFS1/PPARGC1A/IKBKG/ISL1/UNC5B/CBL/LGMN
GOBP_REGULATION_OF_PROTEIN_SECRETION 191 0.4111079 1.546086 0.0015145 0.0248918 0.0204497 3032 NOS2/ANO1/CYP51A1/TLR4/ACHE/ADCY5/SLC9B2/CNR1/HMGCR/SFRP1/RSAD2/PCK2/ADAM8/PPARG/IL1A/SLC12A2/LRRC8A/CPT1A/APOE/ADAM9/TTN/DOC2B/RAB11FIP1/STX1A/LLGL2/HIF1A/BRSK2/TNF/IRS2/GPR27/TRPM4/CCL5/CCN3/FKBP1B/ACSL4/SLC8B1/ATP13A2/AACS/VSNL1/BMP6/PIM3/MCU/EIPR1/STXBP5/EFNA5/RAB11FIP5/GPER1/STX4/PTPN11/RHBDF2/ACVR1C/PPARD/ALOX5/RHBDD3/MYO18A/MIDN/PFKFB2/DNAJC1/ISL1/RHBDF1/DISP1/ICA1
GOBP_REGULATION_OF_RESPONSE_TO_WOUNDING 124 0.4601912 1.645588 0.0015336 0.0250361 0.0205683 1658 CCN4/C1QTNF1/SERPINB2/RTN4R/HBEGF/SERPINC1/PHLDB2/FAP/KLF4/DUOX2/CD36/F3/PLAU/SLC12A2/FGF2/CLASP1/SMOC2/DUOX1/APOE/EDN1/TNFRSF12A/CD9/ANXA1/EPPK1/THBD/OCLN/CEACAM1/TNF/CLDN4/ST3GAL4/THBS1/NDEL1/FKBP1B/SH2B3
GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY 131 0.4531594 1.633660 0.0015445 0.0251267 0.0206427 3267 IL19/GDNF/SFRP1/BCL2/IL1A/IFI6/TNFSF12/TMBIM1/PMAIP1/TNFRSF12A/TMC8/PML/ICAM1/TNF/CX3CL1/PEA15/HMOX1/YAP1/THBS1/ITGA6/ITGAV/FADD/EYA4/RBCK1/LMNA/CTTN/SCG2/TNFAIP3/BCL2L14/ATF3/BCL10/LTBR/AKT1/TGFBR1/GPER1/RELA/RFFL/CYLD/STX4/SRC/CSF2/BID/PAK2/LGALS3/CAV1/SIAH2/UNC5B/PELI3/ARHGEF2/STRADB/EYA3/EYA2/HTT/SH3RF1/ZC3HC1
GOBP_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT 65 0.5399947 1.757336 0.0015704 0.0254598 0.0209163 1617 ANO1/GABRA4/SLC5A5/SLC26A4/SLC26A9/SLC5A1/ANO2/CLIC2/ANO4/SLC12A2/LRRC8A/SLC26A6/SLC26A11/PTAFR/CLCN6/ANO7/SLC25A3/SLC12A4/APOL1
GOBP_RECEPTOR_RECYCLING 31 0.6604107 1.847157 0.0016036 0.0258790 0.0212608 3457 ACHE/PCSK9/LDLR/EHD3/PHETA2/PLEKHJ1/ECE1/OPTN/SNCA/SORL1/RAB29/LAMTOR1/SCRIB/TBC1D16/INPP5F/LMTK2/ANXA2
GOBP_RESPONSE_TO_NICOTINE 34 0.6478476 1.841243 0.0016184 0.0258790 0.0212608 1329 NTRK1/LYPD1/CNR1/SLC7A11/BCL2/EDN1/TNF/HMOX1
GOBP_PROTEIN_LOCALIZATION_TO_CHROMATIN 31 -0.6245187 -1.828990 0.0016185 0.0258790 0.0212608 3218 RUVBL2/MSH2/MRNIP/ESR1/EZH2/LRWD1/FAM47E/MCM8/H1-5/CDCA5/PLK1/ESCO2
GOBP_REGULATION_OF_MAP_KINASE_ACTIVITY 157 0.4228067 1.551106 0.0016104 0.0258790 0.0212608 1840 RASGRP1/FZD10/TLR4/PTPN22/TRIB3/HMGCR/SFRP1/ADAM8/PPARG/SPRY4/NOD2/ARHGEF5/FLT1/UCHL1/NTRK3/VEGFA/FZD5/CBLC/FGF2/APOE/ADAM9/EDN1/KITLG/FGD2/TRIB1/ROR2/DUSP10/TRIB2/TNF/RGS2/DUSP7/BMP2/THBS1/SERPINB3/SH2B3/MST1R/IRAK1/TGFA
GOBP_ORGANIC_ANION_TRANSPORT 248 0.3893696 1.519383 0.0016594 0.0264421 0.0217234 2250 NOS2/PLA2G3/SLC26A4/SLC26A9/SLC39A8/SLC2A6/SLC5A8/SLC7A11/LRRC8D/SLCO4A1/SLCO1B1/SLC16A9/SLC25A25/ACE/MFSD2A/SLC6A14/NTRK2/CD36/SLC16A4/SLC3A2/IL1A/SLC7A9/SLC12A2/CD47/SLC7A5/LRRC8A/SLC7A1/EDN1/SLC16A14/PLA2G4A/SLC1A5/ANXA1/SLC4A9/SLC36A1/SLCO1B3/SLC26A6/SLC1A4/CEACAM1/SLC16A13/SLCO3A1/TNF/SLC27A4/SLC4A3/SFXN5/ATP8B1/SLC38A1/SLC25A1/LRRC8C/RGS2/SLCO4C1/SLC25A32/SLC5A12/SLC38A7/SLC16A7/SERINC5/SLC6A9/SLC17A5/SLC52A2/P2RX4/SNCA/SLC66A1/PRAF2/MFSD12/GABBR1/SLC16A3/SLC25A23/SLC35D2/SLC25A22/SLC35B4/GRM1/SLC6A11
GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY 82 0.5094217 1.718610 0.0017074 0.0271157 0.0222767 1199 SH2D1B/RASGRP1/RSAD2/CD55/NOD2/PVR/RAET1G/FZD5/CLCF1/GATA3/TNFSF13/RAET1E/NECTIN2/IL18R1/ARID5A/IL23A/TNF
GOBP_ALPHA_BETA_T_CELL_ACTIVATION 108 0.4700641 1.641702 0.0017297 0.0273754 0.0224901 1477 SOCS1/CDH26/CD274/LGALS7B/PTPN22/PRDM1/RSAD2/CD55/BCL11B/PRKCQ/EBI3/BCL2/TOX/GATA3/CD86/RELB/ANXA1/IL18R1/NFKBID/IL23A/ZC3H12A/CD83/ARG2/IL4R/ZBTB7B/LGALS9
GOBP_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY 29 0.6690798 1.828053 0.0017639 0.0278231 0.0228579 1477 SH2D1B/RASGRP1/SERPINB4/PVR/RAET1G/SERPINB9/ARRB2/MICA/RAET1E/NECTIN2/CEACAM1/LGALS9
GOBP_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS 63 0.5548951 1.780369 0.0017804 0.0279896 0.0229947 2389 CD274/SLC7A11/ADAM8/NOD2/PRKCQ/ST6GAL1/PIP/IDO1/IRF7/HSH2D/ANXA1/KITLG/RIPK3/HIF1A/IRS2/ARG2/CCL5/LGALS9/AXL/FADD/PRELID1/CDKN2A/BCL10/ADAM17/SELENOS/GAS6
GOBP_REGULATION_OF_CELL_KILLING 59 0.5552713 1.761770 0.0018222 0.0285504 0.0234554 1780 NOS2/RASGRP1/SERPINB4/CD55/PVR/SERPINB9/ARRB2/MICA/RAET1E/NECTIN2/RIPK3/CEACAM1/IL23A/ICAM1/LGALS9/ITGAM/FADD/CXCL6
GOBP_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION 98 -0.4530832 -1.654312 0.0018316 0.0286015 0.0234974 2983 NOP53/AURKA/RAD51B/ING4/MRNIP/DYRK3/MRE11/CLSPN/ATAD5/PBX1/RRM1/CHEK1/BRCA1/CDC7/HSPA2/ABRAXAS1/CDC25A/BLM/STOX1/FHL1/FBXO5/CCNB1/ORC1/NEK10/KIF14/CENPF/PLK1/TICRR/CDK1/DTL/CDC25C
GOBP_PLATELET_ACTIVATION 99 0.4871085 1.690968 0.0018563 0.0288902 0.0237346 2990 ADRA2C/EMILIN2/C1QTNF1/VWF/SELP/TLR4/SLC7A11/PRKCQ/TYRO3/APOE/PLA2G4A/CD9/P2RY1/THBD/VCL/PEAR1/CEACAM1/AXL/SH2B3/RAP2B/ENTPD2/PLSCR1/MYH9/DGKI/TEC/DGKQ/ACTB/CSRP1/DGKA/UBASH3B/PF4V1/PDPN/ACTN1/SRC/IL6ST/ACTG1/SYK/VAV2/DGKD/MYL12A/COMP
GOBP_NEUROTROPHIN_SIGNALING_PATHWAY 31 0.6538041 1.828679 0.0018730 0.0290540 0.0238691 597 NTRK1/BDNF/NTRK2/NTRK3/PPP2R5B
GOBP_CIRCULATORY_SYSTEM_PROCESS 401 0.3423939 1.406798 0.0019014 0.0293963 0.0241504 1796 NOS2/CLDN5/ADRA1A/ADRA2C/ADM5/SLC5A5/EDNRA/CASQ2/SLC5A1/PTPRO/ADM2/TBXAS1/CXCL10/HOPX/SLC24A3/HBEGF/CNR1/SGK1/HTR1D/CTNNA3/PPARG/KL/CLIC2/ACE/ANPEP/MFSD2A/HRH1/SLIT2/KCNE3/CD36/DLL4/EHD3/KCNMB4/VEGFA/KLF2/SLC29A2/SLC12A2/ANK2/SLC7A5/FGF12/SLC7A1/KLK1/APOE/EDN1/TTN/SLC1A5/P2RY1/KCNK6/SLC5A3/SVEP1/BIN1/OCLN/SLC1A4/CEACAM1/PTGS2/GRIP2/SLCO3A1/PKP2/TNF/ZC3H12A/SLC27A4/SLC4A3/PTP4A3/SLC38A1/HMOX1/YAP1/SEMA3A/RGS2/GCH1/DLG1/PTAFR/TRPM4/ECE1/PLCB3/FYN/FKBP1B/SLC16A7/ATP1B1/SLC9A1/GSN/SLC6A9/NOS1/P2RX4/PDE4B/PLOD3/MYOF/TJP1/STAT1/SLC8A1/CELF2
GOBP_PYRIDINE_NUCLEOTIDE_METABOLIC_PROCESS 27 0.6703270 1.800348 0.0019223 0.0296218 0.0243356 1987 IDO2/SLC5A8/NNMT/HAAO/IDO1/PARP9/NUDT17/QPRT/NAMPT/KYNU/NADK/PARP10
GOBP_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY 47 0.5589751 1.691001 0.0019441 0.0298586 0.0245302 1795 ADRA1A/RASGRP1/EDNRA/FLT1/FGF2/CD86/ANXA1/ANXA8/RGS2/PTAFR/CCL5/GNA15/P2RY6/SNCA/ANXA8L1
GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY 193 0.4117614 1.552355 0.0019524 0.0298876 0.0245540 3305 IL19/GDNF/SFRP1/BCL2A1/TNFRSF10A/BCL2/IL1A/IFI6/TNFSF12/TMBIM1/CD70/PMAIP1/TNFRSF12A/IFI27/TMC8/KITLG/BAK1/PML/ICAM1/TNF/FAS/KRT18/CX3CL1/PEA15/HMOX1/YAP1/THBS1/ITGA6/ITGAV/FADD/EYA4/TNFRSF10C/RBCK1/LMNA/CTTN/SCG2/TNFAIP3/BCL2L14/ATF3/BCL10/LTBR/AKT1/BOK/TGFBR1/GPER1/SGPP1/RELA/RFFL/CYLD/STX4/SRC/CSF2/BID/PAK2/LGALS3/CAV1/SIAH2/UNC5B/CASP2/TNFRSF10B/PELI3/ARHGEF2/STRADB/EYA3/EYA2/HTT/SH3RF1/ZC3HC1/DAXX
GOBP_ALPHA_AMINO_ACID_METABOLIC_PROCESS 164 0.4250741 1.570268 0.0019925 0.0304025 0.0249770 1124 NOS2/IDO2/CBS/SLC39A8/PSAT1/SLC7A11/TAT/KYAT1/ASNS/HAAO/ASPG/IL4I1/BCAT1/PYCR1/PHGDH/IDO1/GPT2/ARHGAP11B/GOT1/ATF4/CTH/SHMT2/GFPT2/HAL
GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION 42 0.6119453 1.811946 0.0020533 0.0311777 0.0256138 1899 CCL26/ALOX15/CDC42EP5/CDC42EP1/HCK/BIN1/SNX9/DLG1/VASP/CTTN
GOBP_SYNAPTIC_TRANSMISSION_GABAERGIC 32 0.6322793 1.787810 0.0020567 0.0311777 0.0256138 574 ADRA1A/GABRA4/CA2/CNR1/PHF24/RAC3
GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE 191 0.4067330 1.529633 0.0020673 0.0312370 0.0256626 2740 SH2D1B/FGL2/PLA2G3/RASGRP1/IL13RA2/TLR4/TCIM/LAT2/IFI35/UNC13D/CLCF1/GATA3/ANXA3/TNFSF13/TICAM1/CD86/RELB/ANXA1/DOCK11/IL18R1/NFKBID/CEACAM1/IL23A/MYD88/ICAM1/ZC3H12A/GAB2/HMOX1/IL4R/PTAFR/ZBTB7B/LGALS9/NR4A3/ITGAM/RIPK2/RNF8/CD46/SHLD2/BATF/SBNO2/HLA-F/RORA/CD177/STX4/IL27RA/BCL3/STXBP2/BCR/LGALS3/SYK/SLC15A4
GOBP_REGULATION_OF_TRANSMEMBRANE_TRANSPORT 390 0.3383822 1.387498 0.0021046 0.0316975 0.0260409 2575 CA2/ARC/THY1/EDNRA/CASQ2/TRIB3/ITLN1/RGS7/CXCL10/PRKD1/KCNS3/TMC1/CACNB4/PCSK9/CEMIP/KCNJ16/CXCL11/KCNH8/GEM/CXCL9/STAC/CLIC2/MAPK8IP2/ACE/KCNE3/EHD3/CLIC3/BCL2/ANTKMT/STOM/RELN/ANK2/G6PD/CACNB1/FGF12/SHISA6/EDN1/KCNQ4/HK2/CLIC4/GRB10/KCNK6/ENPP1/SHISA8/TCAF2/TSPAN13/ACSL1/FXYD6/BIN1/SLC26A6/ERFE/OCLN/TNF/KCNA2/VMP1/CX3CL1/IRS2/PEA15/CATSPER3/RGS2/DLG1/PTAFR/APPL2/CTTNBP2NL/THBS1/OSR1/FYN/FKBP1B/NR4A3/PIM1/ATP1B1/SLC9A1/STIM1/SLC6A9/P2RY6/NOS1/TPCN2/SNCA/OXSR1/PDE4B/SLC8A1/CACNA2D4/ANO9/KCNK15/ACTB/WDR1/CNKSR3/PRNP/SHISA9/AKT1/TMSB4X/STIM2/MYC/SELENOS/UBASH3B/GPER1/NEDD4/SHANK3/DIAPH1/CHP1/SCN1B/COA8/HVCN1/RANGRF/DRD1/PTPN11/FGF13/ARPP19
GOBP_REGULATION_OF_EPITHELIAL_CELL_MIGRATION 205 0.3960726 1.502218 0.0021287 0.0319572 0.0262542 3656 HAS2/HYAL1/PRKD1/HBEGF/PPARG/KLF4/FGFBP1/SLIT2/MIR200A/DLL4/HDAC9/VEGFA/FGF2/CLASP1/GATA3/SMOC2/ANXA3/APOE/ADAM9/EDN1/MET/ANXA1/EPPK1/SCARB1/NRP2/HIF1A/SOX9/CEACAM1/DUSP10/PTGS2/KDR/TNF/ZC3H12A/ADAMTS9/HMOX1/SEMA3A/EPHA2/THBS1/BCAR1/GADD45A/P2RX4/ARSB/RAC1/PTPRG/AKT3/MARVELD3/RHOB/HDAC6/CSNK2B/AKT1/JUN/SH3BP1/TMSB4X/ADAM17/ITGA3/TACSTD2/SRC/HDAC7/MAPRE2/CARD10/PFN1/RAB25/MAP2K3/ATOH8/LGMN/GFUS/RREB1/GPI/STAT5A/MIR149/SPRED1/ACVRL1/PTPN23/PRKCA/PLK2/FOXC2/MACF1/DOCK5/RAB11A/CALR/ATP2B4/MMRN2/JUP/RRAS/MAP4K4
GOBP_RESPONSE_TO_INTERFERON_ALPHA 19 0.7392837 1.855218 0.0021771 0.0325792 0.0267653 2634 IFIT2/MX2/IFIT3/IFITM1/GATA3/BST2/LAMP3/IFITM3/AXL/ADAR/EIF2AK2/GAS6/PDE12
GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY 142 0.4280405 1.553195 0.0021848 0.0325902 0.0267743 3201 TLR4/PTPN22/RSAD2/OAS3/NOD2/TNIP3/OASL/OAS1/CD36/IFI35/MAPKAPK3/IFIH1/DDX60/GPS2/IRF7/TYRO3/ARRB2/UFD1/TICAM1/LY96/MFHAS1/IRAK2/NFKBIA/MYD88/TNF/TNIP1/SLC15A3/APPL2/LGALS9/RNF125/IRAK1/RIPK2/TRIM25/NPLOC4/TNFAIP3/SEC14L1/BCL10/IRAK4/MAPKAPK2/RELA/GFI1/CYLD/NOD1/BIRC3/CLPB/S100A14/SLC15A4/CAV1/SCARA3/FLOT1/DHX58/ERBIN/NINJ1
GOBP_RIBOSE_PHOSPHATE_METABOLIC_PROCESS 330 0.3548423 1.428700 0.0022042 0.0327755 0.0269265 3438 MVD/HMGCS1/SLC2A6/ADCY5/ELOVL6/HKDC1/ACSS2/HMGCR/ADCY4/PDE9A/ELOVL5/PDE8B/ACLY/ALDOB/PDE10A/ACOT1/ANTKMT/ADCY7/GUCY2C/G6PD/DPYD/FBP1/ELOVL7/HK2/XDH/MVK/PRTFDC1/ENPP1/HSD17B12/ACSL1/ALDOC/PANK3/TKT/HIF1A/CARD11/FAR1/MLXIPL/PFKP/ACOT7/SLC25A1/MAGI3/HK1/DLG1/EPHA2/UCKL1/ELOVL1/ACSL4/OGDH/ELOVL4/SNCA/PDE4B/ACACA/NUDT8/ADCY10/UPP1/GPAT4/VPS9D1/GALK1/TAFAZZIN/ENTPD5/FLCN/ENO1/ATP5MC1/TJP2/PDHA1/TMSB4X/RORA/MYC/FOXK1/ATP5F1D/PTHLH/CTPS1/ACOT9/TIGAR/PRXL2C/NT5C2/DLST/PPARGC1A/ACSL3/HACD1/PFKFB2/FOXK2/NUDT16/SIRT6/NPR2/ADPGK/GPI/GIT1/ATP5MC3/GUK1/NCOR1/PMVK/PDE4D/PANK4/SLC26A2/SLC25A16/ADSS2
GOBP_REGULATED_EXOCYTOSIS 172 0.4267388 1.580042 0.0022227 0.0329459 0.0270665 1598 ADRA1A/PLA2G3/TRPV6/RASGRP1/IL13RA2/SNPH/CNR1/LAT2/SYNGR3/UNC13A/ERC2/UNC13D/ANXA3/HYAL3/SYNGR2/DOC2B/RAB11FIP1/P2RY1/HCK/SYT17/STX1A/STX3/SYN2/PPFIA3/CEACAM1/RIMS3/GAB2/SYT11/HMOX1/RAB31/IL4R/PTAFR/SYT1/LGALS9/NR4A3/RAB15/ITGAM/PRKCG
GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION 41 0.5915369 1.740374 0.0022416 0.0331197 0.0272093 1448 HAS2/DPP4/PHLDB2/FAP/FGFR4/CLASP1/RIC1/SOX9/DDR2/BMP2
GOBP_REGULATION_OF_WOUND_HEALING 98 0.4823201 1.666894 0.0022734 0.0334845 0.0275090 1495 CCN4/C1QTNF1/SERPINB2/HBEGF/SERPINC1/PHLDB2/FAP/DUOX2/CD36/F3/PLAU/SLC12A2/FGF2/CLASP1/SMOC2/DUOX1/APOE/EDN1/TNFRSF12A/CD9/ANXA1/EPPK1/THBD/OCLN/CEACAM1/TNF/CLDN4/ST3GAL4/THBS1
GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_INFLAMMATORY_RESPONSE 19 0.7370762 1.849678 0.0022816 0.0334988 0.0275207 1591 PLA2G3/TLR4/NOD2/GBP5/TICAM1/HIF1A/MYD88/TNF/CARD9
GOBP_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION 139 0.4314696 1.567459 0.0023075 0.0337731 0.0277461 2359 FGL2/SOCS1/C1QTNF1/CD274/LGALS7B/PTPN22/PDCD1LG2/MUC21/KLF4/IL4I1/IDO1/VEGFA/CD86/IL1RN/CD9/ANXA1/NOTCH4/CEACAM1/ZC3H12A/DUSP3/ARG2/IL4R/DLG1/BMP2/ZBTB7B/LGALS9/SH2B3/SPINT2/IL20RB/ASS1/BMP6/PRNP/DLG5/SCRIB/PAWR/AKT1/PODXL/TRPV4/UBASH3B
GOBP_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY 135 0.4447346 1.602586 0.0023749 0.0346515 0.0284677 1909 NTRK1/TLR4/PRKD1/ADAM8/NOD2/PRKCQ/CD36/AIM2/RTKN2/TICAM1/CTH/IL18R1/RIPK3/IRAK2/CARD11/MYD88/SLCO3A1/TNF/PSMA6/CX3CL1/SPHK1/RPS6KA4/PRKCH/LGALS9/TRIM14/GREM1/CARD9/TRIM21/EIF2AK2/IRAK1/RBCK1/RIPK2/TRAF5/TRIM25
GOBP_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS 28 0.6598148 1.781532 0.0023893 0.0347524 0.0285506 2787 APOC1/LDLR/LPIN1/MFSD2A/SCARB1/IDH1/ABCA3/TAFAZZIN/CAPN2/CHP1/ACSL3
GOBP_CHROMATIN_REMODELING_AT_CENTROMERE 11 -0.7650642 -1.739526 0.0024043 0.0348626 0.0286411 2253 NASP/MIS18A/HELLS/CENPP/CENPW/OIP5/HJURP
GOBP_ENTRY_INTO_HOST 121 0.4558259 1.627944 0.0024246 0.0350472 0.0287928 2992 CH25H/CD55/LDLR/ANPEP/NPC1/CXCL8/PVR/SLC3A2/IFITM1/TYRO3/CD86/SLC1A5/KRT6A/NECTIN2/TMPRSS2/SCARB1/LAMP3/IFITM3/ICAM1/RNASEK/CAV2/EPHA2/LGALS9/TRIM14/SERPINB3/GSN/AXL/SLC52A2/ITGAV/TPCN2/PLSCR1/TRIM21/TRIM25/CLDN9/CD46/NECTIN4/ITGB7/ITGB6/FCN3/GAS6/SLC20A2/TMPRSS4/TRIM5/SRC/CLDN1/EPS15/DAG1/SMPD1/CAV1/TRIM22/CBL
GOBP_EXTRACELLULAR_MATRIX_DISASSEMBLY 48 0.5612290 1.692093 0.0024327 0.0350568 0.0288007 1724 DPP4/MMP1/KLK7/ADAM8/FAP/FGFR4/MMP19/NOXO1/CLASP1/SH3PXD2B/WASHC1/CAPG/DDR2/MMP11/GSN/MMP10
GOBP_SYNAPSE_ORGANIZATION 327 0.3546898 1.430145 0.0024600 0.0353409 0.0290341 3216 NTRK1/GDNF/ARC/PTPRO/ACHE/FZD9/CACNB4/SLC7A11/BDNF/MAP1B/NTNG1/GPC6/PDZRN3/LRRTM2/NTRK2/ELFN1/DOK7/NTRK3/UNC13A/ERC2/INA/FZD5/RELN/EPHB3/LRP8/ZNF365/CACNB1/APOE/SHISA6/SYNPO/LRRC4/LRFN4/NRP2/PPFIA3/TNF/NRCAM/FZD1/CHCHD10/VSTM5/IL1RAPL2/CX3CL1/DBN1/PCDHB2/IGFN1/DLG1/FYN/SLIT1/ITGAM/NTN1/TUBB/IGSF9/SNCA/ITPKA/CTTN/HDAC6/WASL/MYOT/ACTB/RAB29/ABHD17C/PRNP/DLG5/PDLIM5/PPFIBP1/EFNA5/NGEF/NEDD4/PCDHB6/SHANK3/EIF4G1/ITGA3/CNKSR2/ACTN1/DRD1/FGF13/EPHA7/CBLN3/LRRN3/ACTG1/CFL1/DAG1/GPC4/SETD5/LAMB2/RAPSN/PPFIA1/ARF4/PFN1/SIPA1L1/LGMN/SLITRK6/SLITRK5/WASF1/APBB2/TSC1/CLSTN3/CDH1
GOBP_ALPHA_AMINO_ACID_CATABOLIC_PROCESS 74 0.5018950 1.666222 0.0024739 0.0354321 0.0291090 938 NOS2/IDO2/CBS/TAT/KYAT1/HAAO/IL4I1/IDO1/GPT2/ARHGAP11B/GOT1/SHMT2
GOBP_NEGATIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION 47 0.5530616 1.673111 0.0024851 0.0354824 0.0291503 3339 SOCS1/THY1/SFRP1/CBLC/SOCS3/PARP14/ERRFI1/SH2B3/ZGPAT/CHMP6/GPRC5A/PTK6/ZFYVE28/CADM4/CAV1/CBL/LRRK1/INPP5F/IBTK
GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION 256 0.3754900 1.472544 0.0025257 0.0358617 0.0294620 3475 NTRK1/ADRA1A/RASGRP1/RTN4R/SPRY4/ARHGAP31/ARHGEF5/SLIT2/DENND4A/ARHGAP30/AMOT/ARHGAP11B/ARHGAP21/RELN/DOCK3/RAP1GAP/ARHGAP40/APOE/FBP1/MET/KITLG/FGD2/PRAG1/GMIP/TAGAP/PLEKHG6/RHOD/FGD3/LRRC59/TNFAIP1/PLEKHG1/ARHGAP27/PLEKHG5/KRAS/CDC42SE1/RASA2/ITGAV/ARHGDIA/SIPA1L2/RAC1/RAP1GAP2/PSD4/ARHGEF10/PLCE1/STMN3/RASIP1/CHN1/ARHGAP10/FLCN/SQSTM1/DENND3/SH3BP1/DENND4C/NGEF/ITGA3/MCF2/CYTH3/EPS8L1/SRC/ARHGAP8/MAPRE2/CADM4/BCR/TIAM1/VAV2/TIAM2/AKAP13/MFN2/CRK/SIPA1L1/CBL/GBF1/MYO9B/ARHGEF2/FLOT1/SWAP70/ARHGAP17/ERBIN/HEG1/PLEKHG3/RASAL1/ABR/SPRY2/ARHGEF1/LZTR1/ARFGAP1/KALRN/CYRIB
GOBP_EXOCYTOSIS 275 0.3712608 1.472480 0.0025270 0.0358617 0.0294620 2711 ADRA1A/PLA2G3/TRPV6/RASGRP1/IL13RA2/SNPH/CNR1/LAT2/SYNGR3/UNC13A/ERC2/UNC13D/CLASP1/ANXA3/HYAL3/SYNGR2/DOC2B/ANXA1/RAB11FIP1/P2RY1/WASHC1/HCK/SYT17/STX1A/STX3/LLGL2/SYN2/BRSK2/RAB8B/PPFIA3/CEACAM1/RIMS3/GAB2/SYT11/HMOX1/RAB31/IL4R/PTAFR/CCL5/SYT1/LGALS9/NR4A3/RAB15/ITGAM/PRKCG/SYT16/TPCN2/SNCA/ATP13A2/MYH9/YKT6/RAB9A/CHMP6/VSNL1/EXOC6/SCRIB/MICAL1/STXBP5/HLA-F/RAB11FIP5/CD177/SCRN1/DRD1/STX4/EXOC3/RAPGEF4/GIPC1/MIA3/STXBP2/BCR/RALA/SYK
GOBP_REGULATION_OF_LIPASE_ACTIVITY 62 0.5395983 1.727677 0.0025853 0.0365778 0.0300503 2259 ADRA1A/RASGRP1/EDNRA/APOC1/PCSK6/FLT1/HDAC9/FGF2/CD86/ANXA1/ANXA8/RGS2/PTAFR/CCL5/GNA15/P2RY6/SNCA/ANXA8L1/FURIN/LPAR2/RHOC
GOBP_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS 218 0.3891820 1.490221 0.0026255 0.0370342 0.0304252 2342 NOS2/IDO2/ADCY5/ELOVL6/SLC5A8/ACSS2/NNMT/GARS1/HAAO/ME1/ADCY4/CMPK2/ELOVL5/ACLY/IDO1/ANTKMT/ADCY7/GUCY2C/PARP9/ELOVL7/HSD17B12/ACSL1/QPRT/PANK3/ACOT7/SLC25A1/NAMPT/UCKL1/ELOVL1/ACSL4/NOS1/ELOVL4/SNCA/ACACA/ADCY10/KYNU/UPP1/NADK/VPS9D1/PARP10/TAFAZZIN/FLCN/ENO1/ATP5MC1/PDHA1/TMSB4X/MYC
GOBP_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS 34 0.6303083 1.791395 0.0026397 0.0371224 0.0304977 1857 ALOX15/ELOVL6/ELOVL5/ALOX15B/ELOVL7/HSD17B12/ACSL1/GGT5/FAR1/SLC25A1/GGT7/ELOVL1/ACSL4/ELOVL4/ACACA/AACS
GOBP_REGULATION_OF_PLATELET_AGGREGATION 21 0.6953676 1.787658 0.0026597 0.0371799 0.0305449 2711 EMILIN2/C1QTNF1/PRKCQ/CD9/CEACAM1/SH2B3/UBASH3B/PDPN/IL6ST/SYK
GOBP_NATURAL_KILLER_CELL_ACTIVATION 53 0.5530473 1.715193 0.0026593 0.0371799 0.0305449 2389 RASGRP1/PTPN22/PRDM1/ULBP1/UNC13D/TOX/TYRO3/TICAM1/MICA/ULBP2/IL18R1/IL23A/NFIL3/IL15RA/AXL/ULBP3/ELF4/IL15/HLA-F/GAS6
GOBP_REGULATION_OF_ACTION_POTENTIAL 42 0.6007352 1.778753 0.0026850 0.0373508 0.0306854 1639 ADRA1A/CNR1/CTNNA3/KCNE3/CD36/ANK2/FGF12/BIN1/PKP2/TNF/DLG1/TRPM4/SLC9A1
GOBP_GRANULOCYTE_CHEMOTAXIS 89 0.4758298 1.622164 0.0026879 0.0373508 0.0306854 1788 CCL26/DPP4/TNFAIP6/CXCL10/CCL4/CXCL11/NOD2/CXCL9/HRH1/SLIT2/CXCL8/CCL22/DAPK2/EDN1/ANXA1/S100A7/CXCL1/IL23A/CAMK1D/CX3CL1/ITGA9/CCL5/THBS1/CXCL2/PDE4B/CXCL6/RAC1
GOBP_T_CELL_MIGRATION 45 0.5683371 1.703413 0.0027280 0.0375437 0.0308438 2565 CCL26/CXCL10/CXCL11/ADAM8/CXCL16/SLC12A2/CD200R1/RIPK3/S100A7/ICAM1/CCL5/OXSR1/FADD/ITGB7/MSN/ADAM17/PLEC/CCL20/IL27RA
GOBP_GLYCEROLIPID_BIOSYNTHETIC_PROCESS 217 0.3912031 1.496273 0.0027221 0.0375437 0.0308438 3274 CISH/SOCS1/PNPLA3/ALOX15/PCK2/LDLR/LPIN1/MFSD2A/PLA2G4C/ABHD4/SOCS2/LCAT/LIPH/FGF2/PLA2G4A/ACSL1/SCARB1/GPAT3/LPCAT4/FAR1/SOCS3/PISD/TMEM150A/PIGW/PTPMT1/SELENOI/PLSCR1/ITPKA/GPAT4/PGAP4/PLCE1/PIP4K2A/DGKQ/TAFAZZIN/ACP6/CAPN2/PIP5K1A/INPP1/PIK3C2B/PLD2/INPPL1/DGKA/PTDSS1/LPIN2/PITPNM2/ITPKC/TTC7A/LPIN3/ABHD3/ACSL3/DGKD/INPP5J/PIP4K2C/PLA2G15/PI4K2A/INPP5F/PNPLA2/AGPAT3
GOBP_REGULATION_OF_T_CELL_ACTIVATION 248 0.3817195 1.489531 0.0027340 0.0375437 0.0308438 2283 FGL2/DPP4/SOCS1/RASGRP1/THY1/CD274/LGALS7B/PTPN22/PDCD1LG2/PRDM1/CD55/ADAM8/NOD2/IL4I1/PRKCQ/EBI3/IDO1/IL1A/TOX/CD47/CD70/GATA3/SLC7A1/CD86/ANXA1/CD276/HLA-DOB/TNFSF9/RIPK3/NFKBID/CARD11/CEACAM1/DUSP10/IL23A/ZC3H12A/DUSP3/CD83/ARG2/IL4R/DLG1/ZBTB7B/CCL5/LGALS9/FYN/SPINK5/FADD/IL1RL2/RIPK2/IL20RB/PRELID1/CD46/TNFRSF13C/MAP3K8/IL15/PRNP/BCL10/DLG5/SCRIB/AP3D1/HLA-DQB2/PAWR/AKT1
GOBP_POSITIVE_REGULATION_OF_KINASE_ACTIVITY 394 0.3373173 1.381908 0.0027189 0.0375437 0.0308438 3073 NTRK1/ADRA1A/ADRA2C/SOCS1/RASGRP1/FZD10/NCF1/TLR4/PRKD1/HBEGF/TCIM/CEMIP/ADAM8/NOD2/FGFR4/ARHGEF5/ALKAL1/ACE/NTRK2/FLT1/EREG/DOK7/TNFRSF10A/NTRK3/VEGFA/FZD5/NEDD9/RELN/DOCK3/FGF2/EPHB3/EGR1/LRP8/TYRO3/EEF1A2/CD86/ADAM9/EDN1/MET/KITLG/FGD2/ACSL1/SPATC1L/RIPK3/EPHA3/DAB1/ROR2/IL23A/KDR/MOB3C/TNF/SNX9/DDR2/EPHA10/DLG1/EPHA2/BMP2/CCL5/THBS1/GREM1/CCND3/AXL/MST1R/SNCA/TXN/IRAK1/TGFA/DGKQ/CDC25B/CCNYL1/GPRC5A/PRNP/BCL10/CDKN1A/AKT1/EFNA5/ADAM17/AXIN1/GAS6/MOB2/DIPK2A/SRC/FGF13/TIGAR/EPHA7/PAK2/TAOK3/MAP2K1/SYK/CARD10/DAG1/VAV2/CCNK/RAP1A/AKAP13/CSK/DUSP12/MAP3K13/PFKFB2/IGF2/STRADA/MAP2K3/FERMT2/TNFRSF10B/PKD2/TPD52L1/STRADB/RPTOR
GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION 52 0.5507742 1.694299 0.0027433 0.0375613 0.0308583 1786 ADRA1A/CASQ2/CTNNA3/CLIC2/EHD3/ANK2/BIN1/PKP2/ZC3H12A/RGS2/DLG1/TRPM4/FKBP1B/ATP1B1/SLC9A1/NOS1/P2RX4/PDE4B/SLC8A1
GOBP_PROTEIN_LOCALIZATION_TO_CONDENSED_CHROMOSOME 18 -0.7028049 -1.844694 0.0027925 0.0378076 0.0310606 3683 KNTC1/ZWILCH/IK/HASPIN/MTBP/KNL1/TTK/CDT1/NDC80/CDK1
GOBP_REGULATION_OF_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY 17 0.7407061 1.823251 0.0028040 0.0378076 0.0310606 1771 CLDN5/FZD5/TNF/MYO1C/EPHA2/PRKCH/TJP1
GOBP_NON_MOTILE_CILIUM_ASSEMBLY 59 -0.5085636 -1.677583 0.0028180 0.0378076 0.0310606 4627 TTC8/TMEM17/INTU/BBS1/DISC1/CEP126/CEP250/ARL13B/TMEM107/BBS10/CEP135/TOGARAM1/PIBF1/TMEM216/IFT122/BBS2/CENPJ/TBC1D32/PCM1/IFT57/IFT140/CC2D2A/IFT88/IFT52/FUZ/IFT74/RPGRIP1L/IFT172/IFT80/DYNC2H1/MKS1/BBS4/CCDC13/RP1
GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE 150 0.4267812 1.564925 0.0027975 0.0378076 0.0310606 2865 TNFAIP6/LYPD1/FZD9/SLC7A11/CEMIP/STAC/GPC6/STOM/BBC3/TMBIM1/SHISA6/PLS1/SLC5A3/TCAF2/EPHA3/STX3/TNF/MYO1C/AP2B1/DLG1/EPHA2/PRKCH/FYN/RHOG/ITGAM/PKDCC/GSN/AP2M1/ZDHHC7/PTPN9/ACTB/PRNP/SQSTM1/MTCL1/GBP1/AKT1/GPER1/PICALM/CHP1/RANGRF/ITGA3/STX4/LGALS3/DAG1/MIEF1/GPC4/ACSL3/RAP1A/NMT1/CSK/PPFIA1
GOBP_HEMOSTASIS 172 0.4221044 1.562883 0.0027996 0.0378076 0.0310606 3002 ADRA2C/EMILIN2/C1QTNF1/VWF/SELP/NFE2/SERPINB2/TLR4/PROCR/SLC7A11/SERPINC1/PLAUR/FAP/PRKCQ/CD36/F3/PLAU/TYRO3/APOE/EDN1/PLA2G4A/CD9/P2RY1/THBD/VCL/PEAR1/TFPI2/ANXA8/CEACAM1/ST3GAL4/THBS1/AXL/SH2B3/RAP2B/ENTPD2/PLSCR1/MYH9/DGKI/TEC/DGKQ/ACTB/CSRP1/GNA12/ITPK1/DGKA/UBASH3B/PF4V1/GAS6/PDPN/ACTN1/SRC/IL6ST/ACTG1/SYK/PAFAH2/VAV2/CAV1/DGKD/MYL12A/COMP/GGCX
GOBP_REGULATION_OF_FAT_CELL_DIFFERENTIATION 106 0.4432182 1.548633 0.0028152 0.0378076 0.0310606 2687 CCN4/TRIB3/INSIG1/SFRP1/PPARG/PTPRQ/DDIT3/GPS2/GATA3/JDP2/ENPP1/MSX2/METRNL/DUSP10/PTGS2/TRIB2/ZFP36/TNF/ZC3H12A/WDFY2/YAP1/TRPM4/BMP2/ZBTB7B/MMP11/NOCT/PIM1/CCDC71L/TFE3/HDAC6/ZBTB7C/FLCN/AKT1/RORA/TRPV4/AXIN1/GPER1/KLF5/PPARD/ALOX5
GOBP_MACROAUTOPHAGY 291 0.3630550 1.447718 0.0027720 0.0378076 0.0310606 4746 ATP6V1C2/NOD2/ATP6V0D2/NPC1/UCHL1/ADPRH/SESN2/HSPB8/HIF1A/VPS37B/MAP1LC3B2/GPSM1/KDR/VPS37D/ATP6V0A2/RUBCN/VMP1/RNF213/HMOX1/OPTN/RAB43/TBC1D14/ATP13A2/RIPK2/PIP4K2A/HDAC6/ATP6V1E2/CHMP6/TAFAZZIN/SQSTM1/CHMP7/AKT1/ATG4D/AUP1/NEDD4/SRC/PLAA/EPM2A/ATG2A/TMEM41B/MCOLN1/NOD1/TIGAR/NRBP2/CALCOCO2/DDRGK1/LARP1/STX12/IKBKG/MFN2/SMCR8/PIP4K2C/ATG101/VPS4A/VPS4B/TSC1/HTT/CHMP1B/PACS2/ILRUN/MAP1LC3B/ATG9A/ATG7/SNF8/TP53/PLEKHM1/PGAM5/VPS37A/GABARAPL1/ATP6V1H/ARL8B/SPTLC2/VTI1A/ERN1/RETREG3/EXOC8/PHF23/SNX30/UBQLN1/CDK5R1/CDC37/MTOR/GNAI3/RAB7A/SLC25A5/TP53INP2/TBC1D25/VCP/MVB12A/RHEB/ATG13/UFM1/MAPK3/ATP6V0A1/USP36/RAB5A/PSEN1/ATP6V0B/ATP6V1B2/ATP6V0D1/ZFYVE1/RALB/VPS26A/NUPR1/UBXN2A/CAPN1/VIPAS39/SMG1/TECPR1/ATG16L1/ACBD5/VPS33B/UBQLN4/RNF41/RAB3GAP2/CHMP1A/ATP6V0E1/PIKFYVE/STAM/CHMP3/SPTLC1
GOBP_CELL_PROLIFERATION_IN_FOREBRAIN 18 -0.7012807 -1.840694 0.0028305 0.0378668 0.0311092 2532 PCM1/CEP120/DIXDC1/FGFR2/GLI3/WNT3A/ARX/DCT/SIX3/KIF14
GOBP_INTERLEUKIN_6_PRODUCTION 110 0.4463825 1.567427 0.0029014 0.0384920 0.0316229 2915 NOS2/TLR4/PTPN22/NOD2/CD36/EREG/IL36A/KLF2/IFIH1/IL1A/CD47/ARRB2/TICAM1/CD200R1/ARID5A/TMEM106A/MYD88/TNF/ZC3H12A/CX3CL1/SYT11/PTAFR/LGALS9/NLRP10/CARD9/IL1RL2/RIPK2/TNFAIP3/AKIRIN2/BCL10/CAPN2/TRPV4/SELENOS/GAS6/MAPKAPK2/PTPN11/IL27RA/NOD1/MAPK13/SYK/CSK/IL17RA/ISL1
GOBP_POSITIVE_REGULATION_OF_ION_TRANSPORT 181 0.4050652 1.518090 0.0028863 0.0384920 0.0316229 1732 PLA2G3/GDNF/ARC/THY1/EDNRA/RGS7/CXCL10/CCL4/CEMIP/CXCL11/CXCL9/STAC/EHD3/IL1A/ANTKMT/RELN/SLC12A2/ANK2/G6PD/FGF12/ORAI1/ARRB2/EDN1/PLA2G4A/ATF4/P2RY1/BAK1/TRPV3/PKP2/PRSS8/VMP1/CX3CL1/DLG1/PTAFR/CCL5/SYT1/ATP1B1/SLC9A1/STIM1/SLC6A9/P2RY6/NOS1/P2RX4/SNCA
GOBP_CALCIUM_ION_TRANSPORT 281 0.3668018 1.459080 0.0029019 0.0384920 0.0316229 1831 ADRA1A/TRPV6/TRPM6/THY1/EDNRA/CASQ2/CXCL10/PRKD1/SLC24A3/STC2/TMC1/CACNB4/CCL4/CEMIP/CXCL11/GEM/CXCL9/STAC/CLIC2/SLC25A25/ACE/HOMER2/EHD3/SLC3A2/BCL2/DDIT3/ANK2/FGF2/G6PD/CACNB1/ORAI1/ARRB2/EDN1/ITPR3/GJA4/CYP27B1/TSPAN13/BAK1/BIN1/MCUR1/PML/EPB41/PTGS2/TRPV3/VMP1/CX3CL1/CATSPER3/CALCRL/BSPRY/SLC35G1/TRPM4/CCL5/FYN/FKBP1B/ATP1B1/SLC9A1/MCUB/STIM1/P2RY6/NOS1/P2RX4/ITGAV/TPCN2/SNCA/PDE4B/SLC8A1/CACNA2D4/VDR/SLC8B1
GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING 175 0.4076820 1.514459 0.0029596 0.0391458 0.0321600 4063 TLR4/PRKD1/NOD2/MAP3K14/CD36/UBD/IL1A/EDAR/BST2/SECTM1/TICAM1/LURAP1/NEK6/CTH/LURAP1L/CARD11/TMEM106A/CANT1/MYD88/TNF/CX3CL1/HMOX1/IFIT5/PLEKHG5/LGALS9/TNFRSF19/FYN/TRIM14/CARD9/SHISA5/FADD/NDFIP2/TRIM21/IRAK1/RBCK1/RIPK2/TRAF5/TRIM25/BCL10/LTBR/RHOC/IRAK4/RELA/TRIM5/MUL1/NOD1/BIRC3/SLC20A1/TRAF3IP2/AKAP13/IKBKG/IKBKE/TRIM22/TNFRSF10B/TFRC/EDA2R/PLK2/DDX21/FKBP1A/TRADD/TNIP2/AJUBA/FLNA/MALT1/RIPK1/GOLT1B/TAB3/TIRAP/LITAF/ECT2/CD40
GOBP_NEUTRAL_LIPID_METABOLIC_PROCESS 93 0.4900638 1.695529 0.0029769 0.0392625 0.0322559 2004 PNPLA3/APOC1/AADAC/LIPG/PCSK9/INSIG1/PCK2/LDLR/LPIN1/MFSD2A/PNPLA1/LIPH/CPT1A/APOE/PLA2G4A/ACSL1/SCARB1/GPAT3/APOBR/SNCA/DGKI/GPAT4/PLCE1/DGKQ/SORL1
GOBP_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE 120 0.4533610 1.606831 0.0030143 0.0396448 0.0325699 1689 IL13RA2/TLR4/PTPN22/KLK7/RSAD2/CD55/NOD2/RAET1G/CD36/FZD5/CLCF1/SLC7A5/GATA3/BST2/TNFSF13/TICAM1/CD86/IL18R1/ARID5A/SEMA7A/TNF/HK1/HMOX1/IL4R/TRPM4/NR4A3/SPINK5
GOBP_KERATINOCYTE_PROLIFERATION 38 0.5997938 1.741518 0.0030360 0.0398176 0.0327119 1828 HAS2/PRKD1/BCL11B/EREG/SFN/SDR16C5/EPPK1/KLF9/ZFP36/CDH3/YAP1/IRF6/VDR
GOBP_MONOSACCHARIDE_METABOLIC_PROCESS 216 0.3923756 1.499303 0.0030549 0.0399537 0.0328237 2938 OTOGL/C1QTNF1/HKDC1/PCK2/NNMT/OAS1/PHLDA2/ALDOB/PPP1R3G/SESN2/G6PD/CPT1A/PMAIP1/FBP1/HK2/GALT/ATF4/ENPP1/ALDOC/ERFE/PFKP/TNF/PFKFB4/SLC25A1/IRS2/HK1/FUOM/FUT2/PPP1R3C/GDPGP1/UXS1/FAM3C/NLN/DGKQ/ATF3/GALK1/PMM2/SLC39A14/PGD/SLC35B4/ENO1/PDHA1/AKT1/KAT2B/RORA/MYC/SELENOS/INPPL1/FOXK1/CHST1/SRC/ARPP19/PGM5/TIGAR/PPARD/FUT4/GPT/PPARGC1A/AKR1A1/DUSP12/MIDN/PFKFB2/IGF2/FOXK2
GOBP_CARBOXYLIC_ACID_TRANSPORT 190 0.3951567 1.483391 0.0030657 0.0399824 0.0328473 2117 NOS2/PLA2G3/SLC26A4/SLC26A9/SLC5A8/SLC7A11/LRRC8D/SLCO1B1/SLC16A9/ACE/SLC6A14/NTRK2/CD36/SLC16A4/SLC3A2/IL1A/SLC7A9/SLC12A2/SLC7A5/LRRC8A/SLC7A1/EDN1/SLC16A14/PLA2G4A/SLC1A5/ANXA1/SLC36A1/SLCO1B3/SLC26A6/SLC1A4/CEACAM1/SLC16A13/SLCO3A1/TNF/SLC27A4/SFXN5/ATP8B1/SLC38A1/SLC25A1/LRRC8C/RGS2/SLC25A32/SLC5A12/SLC38A7/SLC16A7/SERINC5/SLC6A9/SLC17A5/P2RX4/SNCA/SLC66A1/PRAF2/MFSD12/GABBR1/SLC16A3/SLC35D2/SLC25A22
GOBP_MYELOID_LEUKOCYTE_ACTIVATION 161 0.4159091 1.536455 0.0030878 0.0401584 0.0329919 2718 PLA2G3/RASGRP1/IL13RA2/TLR4/IL1RL1/CNR1/CTSC/BATF3/MT1G/LAT2/BATF2/LDLR/CXCL8/IL31RA/UBD/IFI35/UNC13D/ANXA3/TICAM1/ADAM9/RELB/PLA2G4A/ANXA1/NECTIN2/MFHAS1/TMEM106A/ITGB8/MYD88/TNF/ZC3H12A/GAB2/CX3CL1/SYT11/HMOX1/SPHK1/IL4R/PTAFR/CCL5/LGALS9/THBS1/NR4A3/ITGAM/JUND/SNCA/CXCL6/PLSCR1/IL15/BATF/ITGB6/SBNO2/LTBR/JUN/RORA/JMJD6/CD177/STX4/CSF2/STXBP2/BCR/SYK/MYO18A
GOBP_REGULATION_OF_CILIUM_BEAT_FREQUENCY 15 -0.7121416 -1.777940 0.0031352 0.0404373 0.0332211 3365 CFAP20/CCDC39/BBS2/GAS2L2/DNAAF1/BBS4/CFAP43/CFAP45/CFAP206/TTLL6/ODAD2
GOBP_LEUKOCYTE_DEGRANULATION 50 0.5591552 1.701833 0.0031287 0.0404373 0.0332211 2711 PLA2G3/RASGRP1/IL13RA2/LAT2/UNC13D/ANXA3/HCK/CEACAM1/GAB2/HMOX1/IL4R/PTAFR/LGALS9/NR4A3/ITGAM/HLA-F/CD177/STX4/STXBP2/BCR/SYK
GOBP_REGULATION_OF_ION_TRANSPORT 445 0.3294041 1.366186 0.0031319 0.0404373 0.0332211 2457 PLA2G3/GDNF/CA2/ARC/THY1/EDNRA/CASQ2/RGS7/CXCL10/PRKD1/KCNS3/STC2/TMC1/CACNB4/PCSK9/CNR1/CCL4/CEMIP/KCNJ16/CXCL11/KCNH8/GEM/CXCL9/STAC/CLIC2/MAPK8IP2/ACE/KCNE3/HOMER2/EHD3/CLIC3/BCL2/IL1A/ANTKMT/STOM/RELN/SLC12A2/ANK2/G6PD/CACNB1/FGF12/ORAI1/ARRB2/SHISA6/EDN1/KCNQ4/PLA2G4A/ATF4/CLIC4/P2RY1/KCNK6/SHISA8/TCAF2/TSPAN13/SYT17/FXYD6/BAK1/BIN1/PML/EPB41/PTGS2/TRPV3/PKP2/TNF/ATP8B1/PRSS8/KCNA2/VMP1/CX3CL1/SYT11/CATSPER3/RGS2/DLG1/PTAFR/CCL5/SYT1/OSR1/FYN/FKBP1B/ATP1B1/SLC9A1/STIM1/SLC6A9/P2RY6/NOS1/P2RX4/TPCN2/SNCA/NKAIN3/OXSR1/PDE4B/SLC8A1/CACNA2D4/SLC8B1/ANO9/KCNK15/GABBR1/WDR1/HOMER3/CNKSR3/PRNP/PACSIN3/ATP1A1/SHISA9/AKT1/TMSB4X/STIM2/UBASH3B/GPER1/NEDD4/SHANK3/DIAPH1/CHP1/SCN1B/COA8/HVCN1/RANGRF
GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY 443 0.3385238 1.404971 0.0031771 0.0408642 0.0335718 1511 CCL26/CISH/ANO1/ADRA1A/ADRA2C/ADM5/CA2/LGR6/EDNRA/FZD10/LGR5/GRK5/ADM2/FZD9/DEFB4A/RGS7/ADCY5/CXCL10/CNR1/CCL4/HTR1D/OR5P3/RASD1/CXCL11/OR5P2/PPARG/CXCL9/ATRNL1/PHF24/ADCY4/HRH1/CXCL8/CCL22/HOMER2/OR2I1P/EREG/GPR146/ALOX15B/FZD5/ADCY7/LPAR5/TYRO3/ARRB2/APOE/EDN1/RGS16/HPGD/ITPR3/MET/OR2A7/GNAZ/ANXA1/P2RY1/CCR3/GRK7/S1PR3/CXCL1/IGF2R/GPR143/FZD1/RGS20/RGS9/CX3CL1/CGB7/CALCRL/SPHK1/GPR27/RGS2/PTAFR/ECE1/CCL5/GNA15/BCAR1/PLCB3
GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION 105 0.4497895 1.570660 0.0032127 0.0411780 0.0338295 2322 FGL2/SOCS1/CD274/LGALS7B/PTPN22/PDCD1LG2/SFRP1/IL4I1/IDO1/TYRO3/CD86/MICA/ANXA1/CEACAM1/ZC3H12A/DUSP3/ARG2/IL4R/DLG1/ZBTB7B/LGALS9/AXL/IL20RB/TNFAIP3/PRNP/DLG5/SCRIB/PAWR/HLA-F
GOBP_AXON_DEVELOPMENT 382 0.3502834 1.431077 0.0032191 0.0411780 0.0338295 3093 NTRK1/GDNF/THY1/LGR6/EDNRA/DLX5/PTPRO/RTN4R/CNR1/BDNF/SEMA3B/CRMP1/MAP1B/KLF4/PAX6/NTNG1/BCL11B/FOXD1/SLIT2/NTRK2/PRKCQ/UCHL1/ARTN/MAP2/BCL2/VEGFA/OLFM1/RELN/EPHB3/GATA3/APOE/SEMA3D/TUBB3/EDN1/EGR2/TWF2/CHODL/ANOS1/EPHA3/DAB1/NRP2/VCL/BRSK2/PLXNA3/SEMA7A/NRCAM/NIBAN2/EPHA10/ISLR2/DBN1/NREP/SEMA3A/SEMA4C/ATP8A2/ECE1/EPHA2/BRSK1/SEMA6A/FYN/RHOG/SLIT1/NDEL1/FKBP1B/NTN1/DPYSL2/IGSF9/RUFY3/RAC1/KIF5C/VASP/CTTN/ZPR1/HDAC6/MYOT/RAPH1/ACTB/CHN1/SPP1/LIMK1/JUN/EFNA5/PICALM/SCN1B/FOXB1/MCF2/PTPN11/FGF13/EPHA7/PAK2/SHTN1/STK25/MAP2K1/COBL/TIAM1/DAG1/TTL/SEMA4F/LAMA3/EMB/TIAM2/LAMB2/DOCK7/MAP3K13/ISL1/UNC5B/SIPA1L1/SLC9A6/SLITRK6/SLITRK5/DIP2B/FLOT1
GOBP_DNA_REPLICATION_INITIATION 37 -0.5708897 -1.727969 0.0032551 0.0415249 0.0341145 1047 POLA2/ORC1/MCIDAS/CDT1/GMNN/CCNE2/TICRR/GMNC/MCM10
GOBP_COGNITION 222 0.3818983 1.468567 0.0032640 0.0415254 0.0341149 1745 NTRK1/CLDN5/ARC/BRINP1/FZD9/MGAT3/CNR1/SLC7A11/SGK1/AFF2/MME/BDNF/HMGCR/LDLR/MAPK8IP2/MFSD2A/HRH1/NTRK2/CBR3/TMPRSS11E/FOS/RELN/APOE/EGR2/ITPR3/HIF1A/SLC1A4/FOSL1/PTGS2/TNF/SYT11/BRSK1/ST3GAL4/KRAS/FYN/ABCA7/PRKCG/NDRG4/DOP1B/NSUN5
GOBP_NEPHRON_TUBULE_FORMATION 15 0.7431246 1.760954 0.0032942 0.0417956 0.0343369 1561 GDNF/HES5/GATA3/SOX9/WNT6/OSR1/GREM1
GOBP_NATURAL_KILLER_CELL_DIFFERENTIATION 19 0.7262543 1.822521 0.0033265 0.0419565 0.0344691 2389 RASGRP1/PRDM1/TOX/TYRO3/NFIL3/IL15RA/AXL/IL15/GAS6
GOBP_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION 28 0.6473482 1.747872 0.0033518 0.0419565 0.0344691 2711 EMILIN2/C1QTNF1/PLAUR/PRKCQ/CD9/CEACAM1/CCL5/SH2B3/UBASH3B/PDPN/IL6ST/SYK
GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS 64 0.5262953 1.700099 0.0033424 0.0419565 0.0344691 2013 FGL2/PTPN22/IFIT1/AIM2/UFD1/PARP9/IFNLR1/DTX3L/IL23A/ZC3H12A/RNF125/HERC5/STAT1/MICB/NPLOC4/TNFAIP3/SEC14L1/IL15
GOBP_NEURON_DEATH 288 0.3598288 1.429240 0.0033462 0.0419565 0.0344691 2638 NTRK1/PLA2G3/GDNF/TLR4/FZD9/PCSK9/SLC7A11/BDNF/ADAM8/NTRK2/MIR200A/FOS/BCL2/DDIT3/FOXQ1/EGR1/CLCF1/G6PD/GATA3/NES/TYRO3/ARRB2/APOE/AARS1/ATF4/CD200R1/HIF1A/TNF/FAS/FZD1/CASP7/CX3CL1/HMOX1/ASCL1/AP2B1/NSMF/CCL5/KRAS/FYN/NR4A3/ITGAM/PRKCG/SLC9A1/AXL/TBC1D24/SNCA/FADD/ATP13A2/HYOU1/ZPR1/SORL1/RAB29/PRNP/CAPN2/DHCR24/AKT1/JUN/BOK/HLA-F/GRIK2/EIF4G1/PICALM/CHP1/FOXB1/RRAS2/IL27RA/TIGAR/EPHA7/BID/NRBP2/IL6ST/WFS1
GOBP_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT 426 0.3352622 1.390464 0.0033477 0.0419565 0.0344691 3494 ADRA1A/PLA2G3/TRPV6/ARC/APOC1/IL13RA2/ALOX15/PRKD1/PCSK9/CNR1/NOD2/SGIP1/LRRTM2/CD36/IL2RG/VEGFA/UNC13D/CLASP1/CD47/STON2/HYAL3/ARRB2/APOE/DOC2B/ANXA1/P2RY1/COLEC10/HCK/SYT17/STX1A/SCARB1/BIN1/EPHA3/HIP1/RAB8B/CEACAM1/TNF/RIMS3/CAMK1D/RUBCN/GAB2/SYT11/HMOX1/AP2B1/SPHK1/RAB31/IL4R/SMAP1/PTAFR/APPL2/SYT1/LGALS9/ANKRD13B/GREM1/RAB15/ITGAM/PKDCC/ABCA7/PRKCG/IL15RA/AXL/NDRG4/ITGAV/TPCN2/SNCA/AP2M1/EHD1/RAC1/PLSCR1/RAB4B/ATP13A2/RAB9A/DGKQ/TNK2/CHMP6/VSNL1/WASL/SORL1/IL15/RAB29/EIPR1/PACSIN3/TFR2/PACSIN2/SCRIB/MICAL1/AAK1/STXBP5/MSN/HLA-F/STON1/FCN3/C2/GAS6/RAB5B/PICALM/CD177/CD151/DRD1/STX4/SRC/RAPGEF4/GIPC1/STXBP2/BCR/LGALS3/MAP2K1/TBC1D4/RALA/SYK/MYO18A/TBC1D20/ACSL3/SMPD1/RAP1A/CSK/CAV1/DGKD/ANKFY1/PRKAR1B/RAB25/CBL/BET1L/VPS4A/EHD2/FLOT1/VPS4B/SEPTIN1/INPP5F/GIT1/PTPN23/MAP2K2/BSN/DAB2/SNF8/RAB8A/CNN2/RAB11A/ANXA2/CALR/ARFGAP1/SIRPA/CBARP/RAB3A
GOBP_T_CELL_CHEMOTAXIS 17 0.7352127 1.809729 0.0033962 0.0423980 0.0348318 1743 CCL26/CXCL10/CXCL11/CXCL16/SLC12A2/S100A7/CCL5/OXSR1
GOBP_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION 34 0.6203932 1.763215 0.0034230 0.0425090 0.0349230 1199 CLDN5/VEGFA/XDH/BTG1/NOTCH4/S1PR3/VCL/CEACAM1/TNF
GOBP_MITOTIC_SPINDLE_ASSEMBLY 68 -0.4723430 -1.610960 0.0034324 0.0425090 0.0349230 3165 TOGARAM1/MAP9/HSPA1A/CHEK2/PIBF1/KIF23/TOGARAM2/CEP97/RACGAP1/MAP10/ABRAXAS1/KIF11/KIFC1/KIF4A/TPX2/NEK2/PLK1/KIF15/CDC20/MYBL2
GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT 109 0.4445025 1.556802 0.0034317 0.0425090 0.0349230 1786 THY1/CASQ2/CXCL10/PRKD1/TMC1/CACNB4/CEMIP/CXCL11/GEM/CXCL9/STAC/CLIC2/EHD3/ANK2/G6PD/CACNB1/TSPAN13/BIN1/VMP1/CX3CL1/FYN/FKBP1B/ATP1B1/SLC9A1/STIM1/P2RY6/NOS1/SNCA/PDE4B/SLC8A1
GOBP_POSITIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE 15 -0.7083409 -1.768451 0.0034430 0.0425269 0.0349378 2602 MAPK15/ESPL1/ANAPC4/CDT1/DLGAP5
GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION 79 0.4814590 1.617792 0.0034699 0.0427470 0.0351186 2334 CCL26/PRKD1/PPP1R16B/FGFBP1/NR4A1/F3/VEGFA/FGF2/TNFSF12/CCR3/NRP2/HIF1A/KDR/CAV2/HMOX1/BMP2/AKT3/SCG2/BMP6/NRAS/AKT1/JUN/TGFBR1/ADAM17
GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS 38 0.5943798 1.725798 0.0034923 0.0429090 0.0352516 2389 NOD2/PRKCQ/ST6GAL1/PIP/IDO1/IRF7/HSH2D/KITLG/HIF1A/IRS2/ARG2/CCL5/AXL/FADD/BCL10/SELENOS/GAS6
GOBP_POSITIVE_REGULATION_OF_CELL_CYCLE 267 -0.3301359 -1.368781 0.0035109 0.0430246 0.0353466 3038 CHEK2/SLF1/MEIS2/GPSM2/AURKA/RAD51B/RGCC/SPDYA/KIF23/SMPD3/NANOGP8/DYRK3/CENPJ/DRD2/EZH2/MAPK15/SASS6/CEP120/CCN2/ATAD5/CITED2/CKS2/PBX1/RACGAP1/MAP10/RRM1/CHEK1/ESPL1/TGM1/FGFR2/STIL/PRKCE/CDC7/MTBP/INSR/MIR590/ADAMTS1/HSPA2/WNT5A/CDC25A/STOX1/PSRC1/FBXO5/ANAPC4/CCNB1/PIWIL2/EPGN/RAD51AP1/CDC14A/SPAG5/KIF20B/E2F7/CIT/CDT1/CDCA5/NDC80/KIF14/MAD2L1/PLK4/CDK1/RRM2/DTL/DLGAP5/CDC25C/UBE2C
GOBP_PHOSPHATIDIC_ACID_METABOLIC_PROCESS 32 0.6165468 1.743325 0.0035288 0.0431307 0.0354338 2350 PLA2G3/PNPLA3/LPIN1/ABHD4/LIPH/GPAT3/LPCAT4/GPAT4/DGKQ/ACP6/PLD2/DGKA
GOBP_REGULATION_OF_REPRODUCTIVE_PROCESS 116 -0.4179216 -1.553767 0.0035514 0.0431807 0.0354748 1339 OXTR/INSR/CACNA1H/CFAP206/CCDC87/WNT5A/CDC25A/GDF9/PLAT/FBXO5/PIWIL2/TRIP13/GJA1/RAD51AP1/OVGP1/SHH/TTK/UMODL1/FBXO43/ARHGDIB/AR/EPPIN/CDC20/CDC25C/ASPM/CNTD1
GOBP_CELL_GROWTH 400 0.3345992 1.375011 0.0035492 0.0431807 0.0354748 2363 CISH/ADRA1A/EDNRA/HYAL1/TMEM97/RTN4R/HBEGF/SGK1/BDNF/SEMA3B/SFRP1/MEG3/MAP1B/MFSD2A/SLIT2/PRKCQ/TNC/CXCL16/UNC13A/MAP2/BCL2/VEGFA/SOCS2/OLFM1/SESN2/G6PD/BST2/APOE/SFN/SEMA3D/EDN1/TWF2/FBP1/OSGIN1/TMC8/CYP27B1/ENPP1/SYT17/BTG1/KIF26A/NRP2/VCL/PML/SOX9/CEACAM1/PLXNA3/SEMA7A/NRCAM/ISLR2/DBN1/YAP1/SPHK1/SEMA3A/SEMA4C/RGS2/SYT1/SEMA6A/BCAR1/CCN3/SLIT1/GREM1/NDEL1/NTN1/SLC9A1/DPYSL2/SPAG9/RUFY3/CTTN/PLCE1/HDAC6/LTBP4/RAPH1/ITSN2/CDKN2A/LAMTOR1/DCUN1D3/FLCN/CDKN1A/CRLF3/ENO1/SPP1/PDLIM5/LIMK1/AKT1/PAK4/TGFBR1/EFNA5/ADAM17/OGFR
GOBP_PROTEIN_KINASE_B_SIGNALING 152 0.4233909 1.544902 0.0035718 0.0433159 0.0355859 2537 NTRK1/C1QTNF1/HBEGF/ADAM8/NTRK2/GDF15/NTRK3/F3/PLK3/DDIT3/SESN2/FGF2/GATA3/TYRO3/ARRB2/CAVIN3/MET/XDH/MFHAS1/HIP1/FAM110C/PEAR1/SOX9/KDR/TNF/CX3CL1/DLG1/EPHA2/ENG/CCL5/THBS1/LOX/AXL/SH2B3/MST1R/P2RX4/TXN/GCNT2/FLCN/AKT1/TGFBR1/NKX3-1/GPER1/GAS6/SRC/MUL1
GOBP_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY 20 0.6917836 1.769427 0.0035920 0.0433355 0.0356020 1781 SOCS1/PPARG/NLRC5/PARP9/HCK/PARP14/STAT1
GOBP_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION 440 0.3321154 1.379884 0.0035831 0.0433355 0.0356020 2929 NOS2/ANO1/CYP51A1/TLR4/ACHE/ADCY5/SLC9B2/PRKD1/CNR1/SLC7A11/HMGCR/INSIG1/CEMIP/SFRP1/RSAD2/PCK2/ADAM8/PPARG/ARHGEF5/CD36/PLK3/IL1A/FZD5/STOM/BBC3/SLC12A2/LRRC8A/CPT1A/APOE/SFN/ADAM9/TTN/IFI27/DOC2B/RAB11FIP1/TCAF2/STX1A/LLGL2/HIF1A/BRSK2/PTGS2/TNF/ZC3H12A/UHMK1/PTP4A3/MYO1C/IRS2/RIPOR1/GPR27/TRPM4/CCL5/SREBF2/FYN/CCN3/NDEL1/FKBP1B/ITGAM/PKDCC/ACSL4/RUFY3/NDFIP2/TXN/SLC8B1/ATP13A2/AACS/EDEM2/ZPR1/HDAC6/VSNL1/SORL1/EDEM1/RAB29/BMP6/PIM3/MCU/PRNP/EIPR1/MTCL1/STXBP5/EFNA5/RAB11FIP5/GPER1/GAS6/CHP1/STX4/SRC/PTPN11/RHBDF2/FERMT1/ACVR1C/PPARD/ALOX5/RHBDD3/MYO18A/MIEF1/ACSL3/HAX1/NMT1/CSK/MIDN/PFKFB2/BAP1/DNAJC1/ISL1/RHBDF1
GOBP_TRIGLYCERIDE_CATABOLIC_PROCESS 18 0.7039596 1.732414 0.0036176 0.0435323 0.0357637 671 PNPLA3/AADAC/LIPG/PNPLA1/LIPH
GOBP_POSITIVE_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS 104 0.4547825 1.589548 0.0036356 0.0436365 0.0358493 2732 NOS2/PLA2G3/NNMT/PPARG/STARD4/HRH1/ELOVL5/PPP1R3G/CPT1A/PMAIP1/ANXA1/P2RY1/HIF1A/PTGS2/MLXIPL/TNF/IRS2/PTAFR/NR4A3/P2RY6/NOS1/SNCA/TAFAZZIN/ENTPD5/BMP6/MID1IP1/ENO1/AKT1/KAT2B/TMSB4X/MYC/GPER1/SRC/CLYBL/ARPP19/PRXL2C/PPARD/GPT/PPARGC1A
GOBP_EOSINOPHIL_MIGRATION 11 0.7768454 1.713610 0.0037177 0.0445077 0.0365650 1465 CCL26/CCL4/ADAM8/HRH1/DAPK2/CX3CL1/CCL5
GOBP_NEUTROPHIL_CHEMOTAXIS 72 0.4906760 1.621891 0.0037378 0.0445203 0.0365754 1788 CCL26/DPP4/TNFAIP6/CXCL10/CCL4/CXCL11/NOD2/CXCL9/SLIT2/CXCL8/CCL22/DAPK2/EDN1/CXCL1/IL23A/CAMK1D/CX3CL1/ITGA9/CCL5/CXCL2/PDE4B/CXCL6/RAC1
GOBP_GRANULOCYTE_MIGRATION 106 0.4363803 1.524741 0.0037378 0.0445203 0.0365754 2711 CCL26/DPP4/TNFAIP6/CXCL10/CCL4/CXCL11/ADAM8/NOD2/CXCL9/HRH1/SLIT2/CXCL8/CCL22/IL1A/DAPK2/EDN1/ANXA1/S100A7/CXCL1/IL23A/MYD88/CAMK1D/CX3CL1/ITGA9/CCL5/THBS1/RHOG/CXCL2/PDE4B/CXCL6/RAC1/SCG2/WDR1/MCU/TRPV4/IRAK4/PF4V1/CD177/CCL20/LGALS3/FUT4/S100A14/SYK
GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION 136 0.4258987 1.536707 0.0038045 0.0450849 0.0370392 3458 HAS2/HYAL1/PRKD1/HBEGF/FGFBP1/MIR200A/HDAC9/VEGFA/FGF2/CLASP1/GATA3/SMOC2/ANXA3/ADAM9/EDN1/MET/ANXA1/SCARB1/NRP2/HIF1A/SOX9/PTGS2/KDR/ZC3H12A/HMOX1/THBS1/BCAR1/P2RX4/RAC1/AKT3/RHOB/HDAC6/AKT1/JUN/TMSB4X/ADAM17/ITGA3/SRC/HDAC7/MAPRE2/PFN1/RAB25/MAP2K3/ATOH8/LGMN/GFUS/RREB1/GPI/STAT5A/PRKCA/PLK2/FOXC2/DOCK5/RAB11A/CALR
GOBP_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS 288 0.3578688 1.421455 0.0038010 0.0450849 0.0370392 3044 EDNRA/NCF1/TLR4/PRKD1/MGAT3/SLC7A11/LRRC8D/GJB2/PPARGC1B/CPEB2/CD36/PYCR1/FOS/BCL2/KLF2/DDIT3/NFE2L1/SESN2/G6PD/EDN1/RELB/MET/ATF4/ANXA1/EFHD1/RIPK3/HIF1A/PML/PTGS2/TNF/SERPINB6/ZC3H12A/FAS/FZD1/HMOX1/SPHK1/LRRC8C/GCH1/ETV5/FYN/ERRFI1/NR4A3/AXL/TBC1D24/SNCA/OXSR1/CAMKK2/TXN/ATP13A2/AIFM2/RHOB/TNFAIP3/HDAC6/SLC25A23/FANCC/RBM11/PAWR/LETM1/AKT1/JUN/YBX3/TRPV4/MYC/SELENOS/RELA/PLEC/STX4/SRC/STK25/MAPK13/ALOX5/PPARGC1A/ABCC1/SIRT2/EIF2AK3/CAV1/BAG5/LONP1/PKD2/SLC4A11/ARHGEF2
GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION 46 0.5594772 1.682217 0.0038750 0.0455728 0.0374400 1477 SOCS1/CD274/LGALS7B/CD55/PRKCQ/GATA3/CD86/ANXA1/NFKBID/IL23A/ZC3H12A/CD83/ARG2/IL4R/ZBTB7B/LGALS9
GOBP_HOMOTYPIC_CELL_CELL_ADHESION 74 0.4931852 1.637307 0.0038750 0.0455728 0.0374400 2711 EMILIN2/C1QTNF1/SLC7A11/PLAUR/CTNNA3/PRKCQ/CEACAM5/TYRO3/CD9/VCL/PEAR1/CEACAM1/PKP2/CCL5/SH2B3/RAP2B/MYH9/ACTB/CSRP1/TJP2/UBASH3B/DSG2/PDPN/ACTN1/IL6ST/ACTG1/SYK
GOBP_REGULATION_OF_ACTIN_FILAMENT_LENGTH 134 0.4167871 1.504357 0.0038719 0.0455728 0.0374400 4165 CCL26/ALOX15/CDC42EP5/SLIT2/TMOD1/CDC42EP1/ARHGAP40/TWF2/HCK/CFL2/BIN1/CAPG/ESAM/NAA80/TMSB10/SNX9/FLII/DBN1/SVIL/DLG1/GSN/ARPC5L/SSH1/GBA2/VASP/CTTN/KANK3/WDR1/SPTBN5/SH3BP1/TMSB4X/ARPC4/HAX1/TRIOBP/TMOD2/PFN1/SWAP70/SPTBN1/SPTAN1/MYADM/WASHC2C/ARPC5/CYRIB/NCKAP1/ARPC1B/TMOD3/ARPC1A/ARFGEF1/HIP1R/ARF6/MTOR/COTL1/CYFIP1/HCLS1/ADD3/ARPC2/LIMA1/RHOA
GOBP_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION 44 0.5685735 1.698484 0.0039185 0.0459690 0.0377656 1788 NTRK1/RASGRP1/RTN4R/RELN/KITLG/PRAG1/LRRC59/KRAS/ITGAV/RAC1
GOBP_CEREBROSPINAL_FLUID_CIRCULATION 13 -0.7265283 -1.734353 0.0039925 0.0464866 0.0381908 3199 DNAAF11/ODAD4/CCDC39/CFAP54/KATNIP/SPAG16/DNAH9/DAW1/CFAP221/AQP4/CFAP43/CFAP45
GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT 152 0.4214161 1.537696 0.0039879 0.0464866 0.0381908 2575 CA2/ARC/THY1/EDNRA/ITLN1/RGS7/CXCL10/CEMIP/CXCL11/CXCL9/STAC/EHD3/ANTKMT/RELN/ANK2/G6PD/EDN1/ACSL1/SLC26A6/ERFE/OCLN/VMP1/CX3CL1/IRS2/PTAFR/NR4A3/ATP1B1/SLC9A1/STIM1/SLC6A9/P2RY6/NOS1/SNCA/CNKSR3/AKT1/TMSB4X/STIM2/GPER1/SHANK3/CHP1/COA8/DRD1/PTPN11/ARPP19
GOBP_REGULATION_OF_HEMOPOIESIS 281 0.3598674 1.431496 0.0039840 0.0464866 0.0381908 1949 FGL2/PLA2G3/SOCS1/TNFAIP6/RASGRP1/TLR4/SLC9B2/TCIM/PRDM1/SFRP1/ISG15/ADAM8/PPARGC1B/IL4I1/FOS/TOX/KLF13/IRF7/GATA3/CD86/ANXA1/KITLG/TNFSF9/TRIB1/NFKBID/NFKBIA/HIF1A/CARD11/ROR2/CEACAM1/DUSP10/IL23A/ZFP36/TNF/ZC3H12A/CD83/LIF/IL4R/SMAP1/MAPK11/ZBTB7B/LGALS9/LOX/TFE3/IL15RA/AXL/SPINK5/FADD/IL1RL2/STAT1/PRXL2A/RIPK2/PRELID1/CD46
GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY 41 0.5763939 1.695821 0.0040086 0.0465579 0.0382493 1949 IL13RA2/SERPINB4/CD55/NOD2/IL4I1/SERPINB9/BST2/ARRB2/MICA/CEACAM1/AHR/HMOX1/LGALS9/IL20RB/CD46
GOBP_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY 81 0.4803281 1.612230 0.0040572 0.0470057 0.0386172 2607 ADRA1A/THY1/NCF1/HBEGF/ALKAL1/ACE/EREG/DOK7/NEDD9/CBLC/RELN/DOCK3/LRP8/CCL5/ERRFI1/GREM1/RAP2B/ZGPAT/TGFA/RAP2C/CHMP6/GPRC5A/PRNP/PTK6/ZFYVE28/ADAM17/GAS6/SRC/PAK2
GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_DISASSEMBLY 14 0.7607943 1.769506 0.0040953 0.0473287 0.0388826 1266 DPP4/FAP/FGFR4/CLASP1/DDR2
GOBP_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER 48 0.5432349 1.637841 0.0041266 0.0474559 0.0389871 2543 CLDN5/EDNRA/PPP1R16B/VEGFA/FASN/S1PR3/VCL/MYD88/ICAM1/TNF/RAP2B/TJP1/RAP2C/TJP2/MSN/CLDN1
GOBP_MYELOID_LEUKOCYTE_MIGRATION 159 0.4091674 1.512465 0.0041188 0.0474559 0.0389871 1788 CCL26/DPP4/TNFAIP6/PTPRO/CXCL10/CCL4/CXCL11/ADAM8/NOD2/CXCL9/ARHGEF5/HRH1/SLIT2/CXCL8/CCL22/FLT1/VEGFA/IL1A/DAPK2/CD47/PLA2G7/EDN1/CD9/ANXA1/CD200R1/S100A7/ROR2/CXCL1/IL23A/MYD88/CAMK1D/CX3CL1/ITGA9/CCL5/THBS1/RHOG/CXCL2/CCN3/GREM1/MMP28/P2RX4/PDE4B/CXCL6/RAC1
GOBP_REGULATION_OF_CELLULAR_RESPIRATION 44 0.5676728 1.695793 0.0041960 0.0481349 0.0395450 2732 NOS2/SHMT2/IFNLR1/HIF1A/MLXIPL/TNF/SNCA/PRELID1/SLC25A23/FLCN/TRPV4/MYC/PDE12/PPARGC1A
GOBP_TELOMERE_ORGANIZATION 151 -0.3832947 -1.486710 0.0042361 0.0484762 0.0398253 3819 PTGES3/H3-3A/ERCC4/HSP90AA1/H3C6/H4C5/ATM/BRCA2/H4C12/NAF1/WRAP53/TENT4B/WRN/SMC6/H4C6/EZH2/MAPK15/H4C3/H4C2/MRE11/ERCC1/H3C11/H3C1/DNA2/RPA3/ZSCAN4/H4C4/H4C1/BLM/H3C10/PKIB/RECQL4/H4C13/H4C9/EXO1/H3C7/H3C12/NEK2/CCNE2/H3C3/H3C8/H3C2
GOBP_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION 199 0.3894190 1.474555 0.0042484 0.0484978 0.0398430 2622 ADRA1A/SOCS1/THY1/NCF1/HBEGF/SFRP1/CD44/NOD2/ALKAL1/ACE/CD36/EREG/IL31RA/DOK7/HES5/PPP2R5B/VEGFA/NEDD9/CBLC/RELN/DOCK3/CLCF1/LRP8/ARRB2/PARP9/KITLG/IL23A/TNF/SOCS3/LIF/PARP14/CCL5/FYN/ERRFI1/GREM1/SH2B3/RAP2B/ZGPAT/TGFA/RIPK2/TEC/RAP2C/DGKQ/TNK2/CHMP6/IL15/GPRC5A/BMP6/PRNP/PTK6/EFNA5/ZFYVE28/ADAM17/GAS6/SRC/PTPN11/CSF2/EPHA7/PAK2/CADM4/IL6ST
GOBP_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY 24 -0.6348758 -1.779833 0.0042611 0.0485243 0.0398648 918 FBXO5/CDC20B/MAD2L1/PLK1/CDC20/UBE2C
GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY 39 0.5835059 1.706834 0.0044006 0.0499911 0.0410699 1788 GDNF/EDNRA/SEMA3B/SEMA3D/EDN1/MET/NRP2/PLXNA3/SEMA7A/SEMA3A/SEMA4C/ECE1/SEMA6A/ARHGDIA/RAC1

GOMF

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
GOMF_CYTOKINE_RECEPTOR_BINDING 172 0.5143361 1.944547 0.0000014 0.0012845 0.0011657 2711 CCL26/NTRK1/DEFB4A/CXCL10/CCL4/BDNF/RASL11B/CXCL11/IL36G/CXCL9/CXCL8/CCL22/EBI3/CXCL16/IL36A/VEGFA/SOCS2/IL1A/CLCF1/TNFSF12/TMBIM1/CD70/YARS1/GATA3/NES/TNFSF13/IL1RN/KITLG/OSMR/PXDN/TNFSF9/CXCL1/IL23A/MYD88/TNF/LIFR/CX3CL1/LIF/SPRED2/ENG/CCL5/CXCL2/GREM1/SH2B3/FADD/CXCL6/STAT1/TRAF5/IL15/TGFBR1/EFNA5/ADAM17/IRAK4/PF4V1/CCL20/IL27RA/CSF2/BID/CADM4/IL6ST/S100A14/SYK
GOMF_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 226 0.4740712 1.847686 0.0000061 0.0019037 0.0017277 2163 SLC18A2/ANO1/GABRA4/SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC39A8/SLC2A6/SLC24A3/SLC5A8/SLC7A11/TTYH2/ANO2/LRRC8D/SLCO4A1/CLIC2/SLCO1B1/SLC25A25/MFSD2A/SLC6A14/ANO4/CD36/CLIC3/SLC3A2/SLC7A9/SLC12A2/SLC7A5/LRRC8A/SLC7A1/SLC1A5/CLIC4/SLC4A9/SLC36A1/LRRC8B/SLCO1B3/SLC26A6/SLC26A11/SLC1A4/ANO8/SLCO3A1/SLC27A4/SLC4A3/SFXN5/SLC38A1/SLC25A1/CLDN4/LRRC8C/SLCO4C1/CLCN6/SLC25A32/SLC5A12/ANO7/SLC12A4/SLC38A7/SLC16A7/APOL1/SLC9A1/SERINC5/SLC6A9/SLC9A4/SLC52A2/VDAC2/SLC66A1/ANO9/MFSD12/PACC1/SLC16A3/SLC25A23/SLC39A14/SLC35D2/SLC25A22/SLC35B4
GOMF_SIGNALING_RECEPTOR_REGULATOR_ACTIVITY 264 0.4481086 1.777212 0.0000050 0.0019037 0.0017277 1945 CCL26/IL19/DPP4/GDNF/LYPD1/INHBE/ADM2/DEFB4A/CXCL10/STC2/HBEGF/PCSK9/CCL4/BDNF/SEMA3B/IL32/CXCL11/KL/IL36G/CXCL9/IL17C/CXCL8/CCL22/TG/EREG/ARTN/GDF15/EBI3/CXCL16/IL36A/VEGFA/IL1A/CMTM3/FGF2/CLCF1/TNFSF12/CD70/FGF12/SECTM1/GNRH1/SEMA3D/TNFSF13/EDN1/IL1RN/OSGIN1/COLEC10/KITLG/PXDN/TNFSF9/ERFE/METRNL/CXCL1/IL23A/SEMA7A/TNF/CX3CL1/CGB7/LIF/SEMA3A/SEMA4C/NAMPT/CMTM7/BMP2/WNT6/CCL5/MACC1/SEMA6A/CXCL2/CCN3/GREM1/MANF/CXCL6/LYPD6B/TGFA/TYMP/NRTN/RLN1/FAM3C/BMP1/SCG2/DGKQ
GOMF_CYTOKINE_ACTIVITY 122 0.5295073 1.913038 0.0000335 0.0078961 0.0071658 2103 CCL26/IL19/INHBE/CXCL10/CCL4/IL32/CXCL11/IL36G/CXCL9/IL17C/CXCL8/CCL22/GDF15/EBI3/CXCL16/IL36A/VEGFA/IL1A/CMTM3/FGF2/CLCF1/TNFSF12/CD70/SECTM1/TNFSF13/EDN1/IL1RN/KITLG/TNFSF9/CXCL1/IL23A/TNF/CX3CL1/LIF/NAMPT/CMTM7/BMP2/WNT6/CCL5/CXCL2/GREM1/CXCL6/FAM3C/BMP1/SCG2/IL15/BMP6/TIMP1
GOMF_CHEMOKINE_RECEPTOR_BINDING 36 0.6796045 1.978611 0.0003554 0.0290473 0.0263609 1781 CCL26/DEFB4A/CXCL10/CCL4/CXCL11/CXCL9/CXCL8/CCL22/CXCL16/YARS1/NES/CXCL1/CX3CL1/CCL5/CXCL2/CXCL6/STAT1
GOMF_ANION_CHANNEL_ACTIVITY 59 0.5955140 1.897812 0.0002931 0.0290473 0.0263609 2009 ANO1/GABRA4/SLC26A9/TTYH2/ANO2/LRRC8D/CLIC2/ANO4/CLIC3/LRRC8A/CLIC4/LRRC8B/SLC26A6/SLC1A4/ANO8/CLDN4/LRRC8C/CLCN6/ANO7/APOL1/VDAC2/ANO9/PACC1
GOMF_MICROTUBULE_MOTOR_ACTIVITY 62 -0.5467905 -1.858639 0.0002339 0.0290473 0.0263609 2903 KIF7/KIF23/KIF6/KIF17/KIF24/KIF27/DNAH7/DNAH9/DNAH1/DYNC2H1/DNAH3/KIF19/KIF22/DNAI2/DNAH6/DNAH10/KIF18A/KIF26B/STARD9/KIF11/DYNLRB2/DNAH2/DNAH5/KIFC1/KIF21A/KIF4A/KIF20B/KIF14/CENPE/KIF15/KIF2C/KIF20A/KIF18B
GOMF_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 106 0.5134834 1.821095 0.0004662 0.0290473 0.0263609 1723 SLC18A2/ANO1/GABRA4/SLC5A5/SLC26A4/SLC26A9/SLC39A8/TTYH2/ANO2/LRRC8D/CLIC2/ANO4/CLIC3/SLC12A2/LRRC8A/CLIC4/SLC4A9/LRRC8B/SLC26A6/SLC26A11/SLC1A4/ANO8/SLC4A3/CLDN4/LRRC8C/CLCN6/ANO7/SLC12A4/APOL1/VDAC2
GOMF_GROWTH_FACTOR_BINDING 110 0.4996999 1.784482 0.0004453 0.0290473 0.0263609 1575 NTRK1/CCN4/IL1R2/PCSK6/COL6A1/KL/FGFR4/FGFBP1/NTRK2/FLT1/CD36/IL2RG/NTRK3/TRIM16/IL1RN/OSMR/PXDN/NRP2/KDR/LIFR/IGF2R/KLB/EPHA2/ENG/THBS1/CCN3/ITGA6
GOMF_CARBOXYLIC_ESTER_HYDROLASE_ACTIVITY 107 0.4984438 1.768844 0.0005260 0.0290473 0.0263609 893 PLA2G3/CA2/TNFAIP6/PNPLA3/AADAC/ACHE/LIPG/ASPG/PLA2G4C/ABHD4/ACOT1/PNPLA1/PLAAT1/LCAT/LIPH/PLA2G7/AARS1/PLA2G4A/IARS1
GOMF_PROTEASE_BINDING 116 0.4900587 1.766773 0.0004256 0.0290473 0.0263609 2488 DPP4/VWF/SERPINB4/SELL/SERPINC1/SERPINB13/FAP/LDLR/NTRK2/TNFRSF10A/F3/BCL2/CSTA/SERPINB9/CD70/TTN/TIMP2/BIN1/TNF/SERPINB6/CSTB/SERPINB3/STIM1/ITGAV/FADD/A2ML1/RIPK2/TNFAIP3/TIMP1/FURIN/PRNP/BCL10/SELENOS/CD177/ITGA3/RFFL/RHBDD2
GOMF_GLYCOSAMINOGLYCAN_BINDING 153 0.4619782 1.730057 0.0002328 0.0290473 0.0263609 1560 CCN4/TNFAIP6/SELP/LGR6/VIT/SELL/POSTN/CXCL10/RTN4R/PCSK6/LIPG/HBEGF/COL13A1/SERPINC1/CEMIP/SFRP1/CXCL11/CD44/NOD2/FGFR4/FGFBP1/SLIT2/CXCL8/VEGFA/LIPH/FGF2/SMOC2/APOE/CHODL/HSD17B12/ANOS1/FBLN7/HAPLN3/NRP2/ITIH2/SULF1/HK1/ENG/SGSH/THBS1/CCN3/SLIT1
GOMF_SERINE_HYDROLASE_ACTIVITY 115 0.4742356 1.705861 0.0005174 0.0290473 0.0263609 3243 DPP4/MMP1/AADAC/ACHE/PRSS3/PCSK6/PCSK9/KLK7/CTSC/OVCH2/ADAM8/FAP/ACE/PRSS27/TMPRSS11E/F3/MMP19/PLAU/RELN/TMPRSS11B/KLK1/KLK12/TMPRSS2/TMPRSS11A/CFB/PRSS8/PRSS36/MMP11/HP/MMP10/C1S/PRSS16/BMP1/PCSK7/FURIN/RHBDL1/KLK10/C2/TMPRSS4/RHBDD2/TMPRSS11F/RHBDF2/RHBDD1/RHBDD3/PRSS22/RHBDF1/LONP1/MMP14/SEC11C/DPP9/MASP1/ST14
GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 167 0.4467726 1.682281 0.0003134 0.0290473 0.0263609 2145 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC5A1/SLC39A8/SLC9B2/SLC24A3/SLC5A8/SLC7A11/SLC9B1/SLCO4A1/SLCO1B1/SLC16A9/MFSD2A/SLC6A14/SLC16A4/SLC3A2/SLC12A2/SLC7A5/SLC28A3/SLC16A14/SLC1A5/SLC5A3/SLC4A9/SLC36A1/SLCO1B3/SLC26A6/SLC26A11/SLC1A4/SLC16A13/SLCO3A1/SLC45A4/SLC4A3/SLC38A1/SLC25A1/SLCO4C1/CLCN6/SLC15A3/SLC5A12/SLC25A3/SLC12A4/SLC35C1/SLC16A7/SLC9A1/SLC6A9/SLC17A5/SLC9A4/SLC8A1/SLC8B1/MFSD12/SLC16A3/SLC39A14/SLC35D2/SLC25A22/MCU
GOMF_PHOSPHATIDYLINOSITOL_BINDING 237 0.4061546 1.591280 0.0004108 0.0290473 0.0263609 3007 THY1/ALOX15/NCF1/SDCBP2/NCF1C/GSDMC/PHLDA2/CEACAM5/NOXO1/TTPA/PLEKHN1/TWF2/ITPR3/PLA2G4A/SH3PXD2B/FGD2/SCARB1/HIP1/CAPG/EPB41/ANXA8/ADAP2/MREG/SNX9/FLII/RUBCN/GAB2/SNX8/SVIL/APPL2/SYT1/TOM1L2/MARK1/SLC9A1/GSN/SNX24/ADAP1/TPCN2/ATP13A2/ESYT1/VEPH1/MYO10/PHLDA1/MYO1E/ZFYVE26/RAB35/PIK3C2B/AKT1/MYO1B/PLD2/ZFYVE28/CERT1/PICALM/HS1BP3/CYTH3/ZCCHC2/CGAS/PITPNM2/ATG2A/SNX10/ITPR2/PITPNB/GGA3/OSBPL5/NCF4/FCHO2/AIDA/ANKFY1/PFN1/FERMT2/GBF1
GOMF_MICROTUBULE_BINDING 245 -0.3862802 -1.573639 0.0003238 0.0290473 0.0263609 2819 SPAG8/MAP6/KIF23/TOGARAM2/KIF6/KIF17/KIF24/KIF27/RMDN2/CCDC181/LRRK2/GAS2L2/FAM161A/MAP1A/CETN3/MAPT/CETN2/DCDC1/RACGAP1/MAP10/MTUS2/HOOK1/CCDC170/CEP44/SAXO2/KIF19/GAS2/KIF22/MDM1/DNAI7/KIF18A/EML6/CCDC187/ABRAXAS1/KIF26B/STARD9/KIF11/VASH2/SPC24/PSRC1/CRYAB/S100A9/RP1/KATNAL2/SPATA4/CAPN6/KIFC1/KIF21A/S100A8/KIF4A/SAXO1/SPAG5/KIF20B/APC2/KIF14/REEP1/CENPF/TPX2/NDRG1/IRAG2/CENPE/PLK1/SKA1/BIRC5/KIF15/KIF2C/KIF20A/GTSE1/DLGAP5/KIF18B
GOMF_ENDOPEPTIDASE_ACTIVITY 286 0.3910058 1.558571 0.0003815 0.0290473 0.0263609 1980 CAPN14/USP26/DPP4/MMP1/TRABD2A/PRSS3/PCSK6/PCSK9/KLK7/CTSC/ADAMTS14/MME/OVCH2/SFRP1/ADAM8/MMP16/FAP/USP28/ACE/PRSS27/PITRM1/UCHL1/CAPN12/TMPRSS11E/PIP/F3/MMP19/PLAU/USP18/TMPRSS11B/MMP25/KLK1/ADAM23/KLK12/ADAM9/MMP17/TMPRSS2/TMPRSS11A/ADAMTSL3/PSMA6/CFB/ADAMTS9/PRSS8/CASP7/PAPPA/ECE1/PRSS36/ADAMTS17/MMP11/NRIP3/BACE2/HP/MMP28/MMP10/C1S/ADAM28/BMP1/NLN/ADAM20/PCSK7
GOMF_TUBULIN_BINDING 335 -0.3459100 -1.456935 0.0005545 0.0290473 0.0263609 2819 SPAG8/MAP6/DNAL1/KIF23/TOGARAM2/CENPJ/KIF6/BCAS3/KIF17/KIF24/KIF27/RMDN2/CCDC181/LRRK2/GAS2L2/AGBL5/FAM161A/MAP1A/TPPP3/CETN3/MAPT/IFT74/EFHC2/CETN2/IFT81/DCDC1/RACGAP1/MAP10/MTUS2/B9D2/HOOK1/EFHC1/DIXDC1/CCDC170/CEP44/SAXO2/KIF19/GAS2/CEP70/BRCA1/KIF22/MDM1/BBS4/AGBL1/DNAI7/KIF18A/EML6/STMND1/STMN1/CCDC187/ABRAXAS1/KIF26B/STARD9/KIF11/VASH2/SPC24/PSRC1/PPP1R42/CRYAB/S100A9/TTLL6/RP1/KATNAL2/SPATA4/CAPN6/GJA1/KIFC1/KIF21A/S100A8/KIF4A/SAXO1/SPAG5/KIF20B/APC2/KIF14/REEP1/CENPF/TPX2/NDRG1/IRAG2/CENPE/PLK1/SKA1/BIRC5/KIF15/KIF2C/KIF20A/GTSE1/DLGAP5/KIF18B
GOMF_PEPTIDASE_ACTIVITY 442 0.3564103 1.474588 0.0006265 0.0295373 0.0268056 3122 CAPN14/FGL2/USP26/DPP4/MMP1/TRABD2A/PRSS3/PCSK6/PCSK9/KLK7/CTSC/ADAMTS14/MME/OVCH2/SFRP1/USP54/ADAM8/MMP16/FAP/USP28/ACE/ANPEP/GGH/PRSS27/PITRM1/UCHL1/CAPN12/TMPRSS11E/PIP/F3/MMP19/PLAU/RELN/USP18/TMPRSS11B/MMP25/KLK1/UFD1/ADAM23/KLK12/ADAM9/MYRF/MMP17/JOSD1/GGT5/TMPRSS2/TMPRSS11A/ADAMTSL3/ZC3H12A/PSMA6/CFB/ADAMTS9/PRSS8/CASP7/PAPPA/CPA6/FOLH1/GGT7/ECE1/PRSS36/LTA4H/ADAMTS17/MMP11/OTUD7A/NRIP3/LACTB/BACE2/NDEL1/USP44/RNPEPL1/HP/MMP28/MMP10/C1S/PRSS16/ADAM28/BMP1/NLN/NCLN/TNFAIP3/ADAM20/PCSK7/METAP1D/QPCTL/FURIN/TFR2/CAPN2/RHBDL1/ATG4D/KLK10/ADAM17/C2/DNPEP/TMPRSS4/USP35/USP14/SCRN1/RHBDD2/TMPRSS11F/CYLD/RHBDF2/USP12/DESI1/RHBDD1/CAPN15/RHBDD3/CPA4/PSMD7/RCE1/ZUP1/PRSS22/PSMB2/BAP1/RHBDF1/CASP2/NUDT16/LONP1/CPQ/LGMN/USP32/USP39/MMP14/PM20D2/SEC11C/MINDY1/HM13/DPP9
GOMF_INORGANIC_MOLECULAR_ENTITY_TRANSMEMBRANE_TRANSPORTER_ACTIVITY 488 0.3431104 1.443806 0.0006004 0.0295373 0.0268056 1862 CALHM4/SLC18A2/ANO1/TRPV6/GABRA4/SLC5A5/SLC26A4/TRPM6/ATP12A/SLC9A3/CALHM5/SLC26A9/SLC5A1/SLC39A8/KCNK3/SLC9B2/KCNS3/SLC24A3/SLC5A8/TMC1/CACNB4/CNR1/TTYH2/KCNJ16/ANO2/KCNH8/LRRC8D/ATP6V1C2/SLC9B1/ATP6V0D2/CLIC2/HTR3B/MFSD2A/KCNE3/ANO4/CNGB3/CLIC3/SLC3A2/KCNMB4/SLC12A2/LRRC8A/CACNB1/ORAI1/TMC6/SLC28A3/HCN2/ITPR3/KCNQ4/SCNN1D/TMC8/CLIC4/KCNK6/SLC5A3/SLC4A9/SLC36A1/LRRC8B/HTR3A/HCN3/SLC30A4/NIPA1/SLC26A6/SLC26A11/SLC1A4/ANO8/TRPV3/ATP6V0A2/SLC45A4/SLC4A3/PIEZO1/SLC38A1/KCNA2/CLDN4/CATSPER3/ATP13A5/LRRC8C/CLCN6/TRPM4/SLC15A3/SLC25A28/SLC5A12/ANO7/SLC25A3/SLC12A4/SLC39A1/FKBP1B/APOL1/ATP1B1/SLC9A1/MCUB/SLC6A9/SLC17A5/SLC9A4/P2RX4/VDAC2/ITGAV/TPCN2/SLC8A1/GRIK4/CACNA2D4/SLC8B1/ATP13A2/ANO9
GOMF_CXCR_CHEMOKINE_RECEPTOR_BINDING 13 0.8050550 1.878297 0.0006834 0.0306858 0.0278479 2380 CXCL10/CXCL11/CXCL9/CXCL8/YARS1/CXCL1/CX3CL1/CXCL2/CXCL6/PF4V1
GOMF_HEPARIN_BINDING 111 0.4847501 1.727721 0.0007182 0.0307866 0.0279394 1058 CCN4/SELP/LGR6/SELL/POSTN/CXCL10/RTN4R/PCSK6/LIPG/HBEGF/COL13A1/SERPINC1/SFRP1/CXCL11/FGFR4/FGFBP1/SLIT2/CXCL8/VEGFA/LIPH/FGF2/SMOC2/APOE/HSD17B12/ANOS1/FBLN7/NRP2
GOMF_PHOSPHOLIPID_BINDING 384 0.3637289 1.490799 0.0008232 0.0337498 0.0306285 2933 PNPLA3/RASGRP1/THY1/APOC1/ALOX15/NCF1/GRK5/MME/SDCBP2/NCF1C/MAP1B/SGIP1/GSDMC/PHLDA2/PLA2G4C/UNC13A/F3/CEACAM5/NOXO1/TTPA/PLEKHN1/ANXA3/PLA2G7/APOE/TWF2/ITPR3/PLA2G4A/SH3PXD2B/DOC2B/ANXA1/FGD2/SYT17/SCARB1/BIN1/HIP1/CAPG/EPB41/ANXA8/ADAP2/MREG/SNX9/FLII/ATP8B1/RUBCN/GAB2/SYT11/SNX8/SVIL/PTAFR/APPL2/SYT1/TOM1L2/THBS1/MARK1/SLC9A1/GSN/AXL/SNX24/ADAP1/CPNE3/RASA2/ANXA4/VDAC2/TPCN2/SNCA/MYOF/CPNE4/ANXA8L1/ATP13A2/PSD4/TEC/ESYT1/VEPH1/MYO10/PHLDA1/MYO1E/ZFYVE26/PACSIN3/PACSIN2/RAB35/PIK3C2B/AKT1/MYO1B/PLD2/ZFYVE28/DGKA/CERT1/GAS6/PICALM/OSBPL1A/HS1BP3/CYTH3/ZCCHC2/CLN6/CGAS/CPTP/PITPNM2/ATG2A/SNX10/ITPR2/PAFAH2/PITPNB/GGA3/OSBPL5/NCF4/FCHO2/AIDA/ANKFY1/PFN1
GOMF_SULFUR_COMPOUND_BINDING 194 0.4136784 1.587453 0.0010318 0.0405411 0.0367918 1780 CCN4/PNPLA3/SELP/LGR6/CBS/SELL/POSTN/CXCL10/RTN4R/PCSK6/LIPG/HBEGF/COL13A1/SERPINC1/SFRP1/CXCL11/FGFR4/FGFBP1/SLIT2/CXCL8/VEGFA/LIPH/FGF2/SMOC2/APOE/ENPP1/HSD17B12/ANOS1/FBLN7/NRP2/PANK3/TKT/NAA80/ACOT7/TPK1/THBS1/CCN3/SLIT1/ACADL/OGDH/CXCL6
GOMF_1_PHOSPHATIDYLINOSITOL_3_KINASE_REGULATOR_ACTIVITY 11 0.8193896 1.807005 0.0011304 0.0409999 0.0372081 1299 CISH/SOCS1/SOCS2/SOCS3
GOMF_PROTEIN_HETERODIMERIZATION_ACTIVITY 262 -0.3584560 -1.475650 0.0011265 0.0409999 0.0372081 1023 H3C10/H2AC16/H2BC7/H2BC3/CYBB/IL12A/BDKRB2/PGLYRP4/H4C13/H2AC13/H4C9/H2AC11/H2AC21/SLC51B/NPAS1/H2BC13/MTTP/GABBR2/H2AC12/MEF2C/H2BC14/H2BC10/BCL2L10/H3C7/CENPW/EPAS1/H2BC17/H3C12/ABCG1/TPM2/KCNB1/ABCD2/H3C3/TOP2A/H3C8/ADRA2A/H3C2
GOMF_NEUROTROPHIN_RECEPTOR_BINDING 10 0.8441598 1.845210 0.0013698 0.0478427 0.0434181 240 NTRK1/BDNF

Reactome

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
REACTOME_CHOLESTEROL_BIOSYNTHESIS 24 0.9100095 2.415338 0.0000000 0.0000000 0.0000000 887 CYP51A1/MVD/ACAT2/HMGCS1/EBP/FDPS/LSS/DHCR7/MSMO1/HMGCR/HSD17B7/IDI1/FDFT1/SQLE/NSDHL/SC5D/TM7SF2/MVK
REACTOME_CELL_CYCLE_CHECKPOINTS 281 -0.4899724 -2.015469 0.0000000 0.0000000 0.0000000 2032 CENPH/CENPS/CCNA2/CENPU/CHEK1/DNA2/B9D2/CENPM/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/CDC7/MCM8/KIF18A/PKMYT1/ABRAXAS1/CDC25A/BLM/BRIP1/SPC24/H2BC7/H2BC3/ANAPC4/CCNB1/ORC1/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/EXO1/SGO2/H2BC14/NDC80/H2BC10/MAD2L1/CENPF/CCNB2/H2BC17/CENPE/NUF2/CCNE2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/MCM10/ERCC6L/CDC20/GTSE1/CDC25C/UBE2C/BUB1B/SPC25
REACTOME_M_PHASE 390 -0.4453607 -1.894092 0.0000000 0.0000000 0.0000000 2064 SMC2/CENPH/H3C11/CENPS/CETN2/H3C1/CENPU/VRK1/B9D2/ESPL1/CENPM/H2BC11/H3C13/CEP78/H2BC15/CEP70/H4C4/H4C1/H2AC4/KIF18A/H3C10/SPC24/H2BC7/FBXO5/H2BC3/ANAPC4/CCNB1/H4C13/CENPK/H4C9/PTTG1/CENPP/PRKAR2B/H2BC13/KNL1/H2AC14/SGO2/CDCA5/H2BC14/NDC80/H2BC10/LMNB1/MAD2L1/CENPF/H3C7/CCNB2/NCAPH/H2BC17/H3C12/CENPE/NEK2/NUF2/PLK1/PLK4/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/KIF20A/CDC20/H3C3/NCAPG/UBE2C/H3C8/BUB1B/SPC25/H3C2
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP 42 0.7926678 2.421620 0.0000000 0.0000003 0.0000002 887 CYP51A1/MVD/HMGCS1/FDPS/ELOVL6/LSS/DHCR7/HMGCR/IDI1/HELZ2/FDFT1/SQLE/SCD/SC5D/FASN/TM7SF2/MVK
REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES 61 -0.6985479 -2.328780 0.0000000 0.0000003 0.0000002 3700 H2AX/H3C6/H2BC6/NCAPD3/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SMC4/H2BC9/SMC2/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/PLK1/CDK1/H3C3/H3C8/H3C2
REACTOME_MITOTIC_SPINDLE_CHECKPOINT 108 -0.6067154 -2.222323 0.0000000 0.0000004 0.0000003 1009 CENPH/CENPS/CENPU/B9D2/CENPM/KIF18A/SPC24/ANAPC4/CENPK/CENPP/KNL1/SGO2/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_DNA_REPLICATION 176 -0.5163359 -2.046794 0.0000000 0.0000010 0.0000009 2017 H3C11/H3C1/CCNA2/DNA2/H2BC11/H3C13/RPA3/POLE2/H2BC15/LIG1/H4C4/H4C1/CDC7/H2AC4/MCM8/GINS1/GINS2/POLA2/H3C10/H2BC7/H2BC3/ANAPC4/ORC1/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/CDT1/GMNN/H2BC14/H2BC10/H3C7/H2BC17/H3C12/CCNE2/MCM10/H3C3/UBE2C/H3C8/H3C2
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 63 -0.6768095 -2.275381 0.0000000 0.0000011 0.0000009 3971 NPM1/H2BC12/RBBP4/ITGB3BP/RUVBL1/RBBP7/CENPC/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MIS18A/H2BC9/MIS18BP1/CENPH/CENPS/CENPU/CENPM/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/H2AC14/H2BC14/H2BC10/CENPW/H2BC17/OIP5/HJURP
REACTOME_HDACS_DEACETYLATE_HISTONES 81 -0.6372707 -2.229347 0.0000000 0.0000011 0.0000009 2162 H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA 61 -0.6767456 -2.256096 0.0000000 0.0000014 0.0000011 3961 H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/PHF19/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES 66 -0.6627525 -2.232308 0.0000000 0.0000014 0.0000011 3831 RBBP7/ACTL6A/H2AX/H3C6/H4C5/SMARCA2/SMARCE1/H4C12/WDR77/H2AJ/H4C6/H2AZ2/H4C3/H4C2/H2AC15/H3C11/H3C1/H3C13/H4C4/H4C1/H2AC4/H3C10/H2AC16/SMARCD3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2AC14/H2AC12/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_MEIOSIS 95 -0.6002354 -2.158029 0.0000000 0.0000014 0.0000011 3813 H3-3A/SYCP2/H2AX/H3C6/H2BC6/H4C5/ATM/BRCA2/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SYNE1/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/DMC1/H3C3/H3C8/H3C2
REACTOME_CHROMOSOME_MAINTENANCE 126 -0.5583225 -2.075482 0.0000000 0.0000014 0.0000011 4152 H2BC8/PRIM1/POLA1/RPA1/NPM1/POLR2I/H2BC12/RBBP4/ITGB3BP/RUVBL1/RBBP7/H3-3A/CENPC/H2AX/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/POLD1/RFC3/WRAP53/H2AJ/WRN/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/MIS18A/H2BC9/CHTF8/MIS18BP1/CENPH/CENPS/CCNA2/CENPU/DNA2/CENPM/H2BC11/RPA3/H2BC15/LIG1/H4C4/H4C1/H2AC4/BLM/POLA2/H2BC7/H2BC3/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/H2AC14/DSCC1/H2BC14/H2BC10/CENPW/H2BC17/OIP5/HJURP
REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION 64 -0.6735249 -2.256106 0.0000000 0.0000014 0.0000011 3961 H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION 56 -0.6751004 -2.208585 0.0000000 0.0000016 0.0000013 4003 SUV39H1/H2BC12/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF 55 0.7512270 2.404642 0.0000000 0.0000016 0.0000013 887 CYP51A1/MVD/HMGCS1/FDPS/ELOVL6/LSS/DHCR7/HMGCR/INSIG1/IDI1/HELZ2/FDFT1/SQLE/SCD/SC5D/FASN/TM7SF2/MVK
REACTOME_MEIOTIC_RECOMBINATION 70 -0.6618302 -2.258802 0.0000000 0.0000016 0.0000013 3700 H2AX/H3C6/H2BC6/H4C5/ATM/BRCA2/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/DMC1/H3C3/H3C8/H3C2
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 54 0.7385567 2.350001 0.0000000 0.0000017 0.0000014 1781 SOCS1/IFIT2/MX2/RSAD2/ISG15/OAS3/ISG20/OASL/IFIT3/OAS1/MX1/IFIT1/IFI35/IFITM1/USP18/IFI6/EGR1/IRF7/BST2/IFI27/XAF1/OAS2/IFITM3/SOCS3/IFIT5/IRF6/ADAR/STAT1
REACTOME_HATS_ACETYLATE_HISTONES 128 -0.5551664 -2.075388 0.0000000 0.0000017 0.0000014 4152 H2BC8/H2BC18/MSL3/MCRS1/MORF4L1/H2BC12/KAT2A/EP400/RUVBL1/RBBP7/ACTL6A/ELP6/H3C6/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/HAT1/H4C6/H2BC4/ING4/H4C3/H4C2/JADE1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 26 -0.8200483 -2.306116 0.0000000 0.0000019 0.0000016 871 ANAPC4/MAD2L1/NEK2/CDC20/UBE2C/BUB1B
REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3 53 -0.6949488 -2.285318 0.0000000 0.0000019 0.0000016 3700 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/AR/H3C3/H3C8/H3C2
REACTOME_RHO_GTPASE_EFFECTORS 290 -0.4445913 -1.840399 0.0000000 0.0000020 0.0000016 1023 H3C10/SPC24/H2BC7/MYLK/S100A9/H2BC3/CYBB/H4C13/CENPK/H4C9/WAS/S100A8/DIAPH3/CENPP/H2BC13/KNL1/H2AC14/SGO2/CIT/NOX1/H2BC14/NDC80/KIF14/H2BC10/MAD2L1/CENPF/H3C7/H2BC17/H3C12/CENPE/NUF2/PLK1/SGO1/IQGAP3/SKA1/BIRC5/AR/KIF2C/BUB1/ERCC6L/CDC20/H3C3/CDC25C/H3C8/BUB1B/SPC25/H3C2
REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION 57 -0.6786559 -2.227959 0.0000000 0.0000024 0.0000020 3700 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ORC1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_DNA_METHYLATION 52 -0.6918105 -2.263368 0.0000001 0.0000030 0.0000024 3813 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION 98 -0.5865076 -2.124470 0.0000001 0.0000031 0.0000026 3961 H2BC12/POLR1C/KAT2A/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE 78 -0.6253839 -2.173370 0.0000001 0.0000032 0.0000026 3961 H2BC12/POLR1C/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX 78 -0.6238631 -2.168085 0.0000001 0.0000036 0.0000030 3852 RUVBL1/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/PYGO1/H2AJ/TCF4/H4C6/H2BC4/H2AZ2/BCL9/H4C3/H4C2/H2BC9/RUNX3/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/AXIN2/H2BC13/H2AC14/TCF7/LEF1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS 95 -0.5820628 -2.092693 0.0000001 0.0000047 0.0000039 3967 POLR2I/H2BC12/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/NUP37/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/NDC1/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS 21 -0.8388424 -2.252758 0.0000002 0.0000067 0.0000055 871 ANAPC4/MAD2L1/CDC20/UBE2C/BUB1B
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION 115 -0.5579830 -2.062884 0.0000002 0.0000095 0.0000079 1009 SPC24/CCNB1/CENPK/CENPP/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CCNB2/CENPE/NUF2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/BUB1B/SPC25
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 97 -0.5690216 -2.050953 0.0000003 0.0000107 0.0000089 2866 H4C6/H2BC4/NOTCH1/MAML3/H2AZ2/H4C3/H4C2/H2BC9/NOTCH3/H3C11/TFDP2/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/ATP2A3/H2BC13/H2AC14/E2F1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/ST3GAL6/MIR449C/H3C3/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS 74 -0.6270305 -2.152107 0.0000003 0.0000109 0.0000090 3700 H2AX/RXRA/H3C6/H2BC6/H4C5/DEK/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/TFDP2/H3C1/CEBPA/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/E2F1/FLI1/LEF1/H2BC14/GATA2/H2BC10/H3C7/MYB/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 96 -0.5724421 -2.062934 0.0000003 0.0000113 0.0000093 4003 SUV39H1/H2BC12/POLR1C/SUDS3/H3-3A/H2AX/H3C6/H2BC6/H4C5/GTF2H5/H2BC5/H4C12/TTF1/H2AJ/SAP30/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_REPRODUCTION 108 -0.5543982 -2.030692 0.0000004 0.0000129 0.0000106 2521 H4C3/H4C2/SYNE1/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/OVGP1/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/CATSPERD/DMC1/H3C3/H3C8/H3C2
REACTOME_HCMV_LATE_EVENTS 103 -0.5576692 -2.037416 0.0000004 0.0000130 0.0000107 2521 H4C3/H4C2/NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE 223 -0.4551216 -1.839857 0.0000004 0.0000133 0.0000110 1009 SPC24/FBXO5/ANAPC4/CCNB1/CENPK/PTTG1/CENPP/KNL1/SGO2/CDCA5/NDC80/LMNB1/MAD2L1/CENPF/CCNB2/CENPE/NUF2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH 89 -0.5836347 -2.066148 0.0000004 0.0000138 0.0000114 4152 H2BC8/PRIM1/POLA1/FOXO3/H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/CDK5/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/CDC25A/POLA2/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/CAPNS2/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/H3C3/CDC25C/H3C8/H3C2
REACTOME_MITOTIC_PROMETAPHASE 191 -0.4729286 -1.881723 0.0000005 0.0000151 0.0000124 1009 PCM1/PDS5B/CEP76/CCP110/SMC4/NME7/SMC2/CENPH/CENPS/CETN2/CENPU/B9D2/CENPM/CEP78/CEP70/KIF18A/SPC24/CCNB1/CENPK/CENPP/PRKAR2B/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CCNB2/NCAPH/CENPE/NEK2/NUF2/PLK1/PLK4/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/NCAPG/BUB1B/SPC25
REACTOME_MITOTIC_PROPHASE 130 -0.5153263 -1.934169 0.0000006 0.0000164 0.0000135 2643 H2AZ2/PRKCB/H4C3/H4C2/SMC4/NDC1/H2BC9/SMC2/H3C11/H3C1/VRK1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/CCNB2/H2BC17/H3C12/PLK1/CDK1/H3C3/H3C8/H3C2
REACTOME_DNA_REPLICATION_PRE_INITIATION 133 -0.5226252 -1.969144 0.0000007 0.0000205 0.0000169 1665 H2BC11/H3C13/RPA3/POLE2/H2BC15/H4C4/H4C1/CDC7/H2AC4/MCM8/POLA2/H3C10/H2BC7/H2BC3/ORC1/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/CDT1/GMNN/H2BC14/H2BC10/H3C7/H2BC17/H3C12/MCM10/H3C3/H3C8/H3C2
REACTOME_INTERFERON_SIGNALING 170 0.5154131 1.942624 0.0000007 0.0000205 0.0000169 2535 SOCS1/IFIT2/MX2/RSAD2/ISG15/CD44/OAS3/ISG20/OASL/GBP5/IFIT3/OAS1/MX1/IFIT1/IFI35/IFITM1/USP18/IFI6/EGR1/IRF7/BST2/IFI27/XAF1/OAS2/PML/IFITM3/ICAM1/SOCS3/PTAFR/IFIT5/UBE2L6/TRIM14/IRF6/HERC5/ADAR/STAT1/TRIM21/EIF2AK2/TRIM25/NUP188/EIF4E3/TRIM45/SEC13/HLA-DQB2/GBP1/HLA-F/HLA-C/STAT2/NEDD4/EIF4G1/TRIM5/PTPN11/GBP4
REACTOME_PHOSPHORYLATION_OF_THE_APC_C 20 -0.8158156 -2.160935 0.0000010 0.0000284 0.0000234 871 ANAPC4/CCNB1/PLK1/CDK1/UBE2C
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS 178 -0.4707924 -1.862121 0.0000013 0.0000339 0.0000279 1009 SPC24/ANAPC4/CENPK/PTTG1/CENPP/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B 24 -0.7811961 -2.161560 0.0000016 0.0000412 0.0000340 871 ANAPC4/CCNB1/CDK1/CDC20/UBE2C
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION 79 -0.5910492 -2.059283 0.0000016 0.0000412 0.0000340 3961 H2BC12/POLR1C/KAT2A/H3-3A/H2AX/H3C6/H2BC6/H4C5/DEK/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 94 -0.5712527 -2.057096 0.0000016 0.0000412 0.0000340 3961 H2BC12/POLR1C/KAT2A/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/DEK/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_BASE_EXCISION_REPAIR 81 -0.5794047 -2.026916 0.0000024 0.0000582 0.0000480 4574 H2AC8/H4C8/LIG3/H2AC6/XRCC1/APEX1/NEIL1/H2BC8/NEIL2/RPA1/H2BC12/UNG/H2AX/NTHL1/H2BC6/H4C5/H2BC5/H4C12/POLD1/RFC3/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/H2BC9/H2BC11/RPA3/POLE2/H2BC15/LIG1/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT 89 -0.5621227 -1.989993 0.0000024 0.0000591 0.0000487 4260 RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/H2AX/H2BC6/H4C5/RAD9B/ATM/H2BC5/H4C12/RFC3/CHEK2/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/H2BC9/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/H2BC17/CDK1/CDC25C
REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION 134 -0.5008421 -1.889252 0.0000036 0.0000846 0.0000697 4003 SUV39H1/H2BC12/POLR1C/KAT2A/RBBP4/SUDS3/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/DEK/H2BC5/H4C12/TTF1/H2AJ/SAP30/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/TET1/H4C4/H4C1/H2AC4/PHF19/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS 16 -0.8401569 -2.091342 0.0000043 0.0000987 0.0000813 1178 PKMYT1/CDC25A/CCNB1/FOXM1/CENPF/CCNB2/PLK1/CDC25C/MYBL2
REACTOME_SIGNALING_BY_INTERLEUKINS 375 0.4114043 1.674962 0.0000047 0.0001064 0.0000877 2711 NOS2/CISH/IL19/SOCS1/IL1R2/IL13RA2/ALOX15/SERPINB2/MMP1/IL1RL1/CXCL10/CCL4/MAOA/IL32/IL12RB2/IL36G/NOD2/IL17C/CXCL8/CCL22/CD36/IL2RG/IL31RA/EBI3/FOS/MAPKAPK3/BCL2/IL36A/VEGFA/SOCS2/IL1A/FGF2/CLCF1/GATA3/CD86/NFKB2/IL1RN/ANXA1/HCK/OSMR/IFNLR1/STX1A/IL18R1/IRAK2/NFKBIA/STX3/HIF1A/PTGS2/CXCL1/IL23A/MYD88/ICAM1/TNF/LIFR/PSMA6/GAB2/SOCS3/DUSP3/IRS2/HMOX1/LIF/IL4R/DUSP7/PTAFR/MAPK11/CCL5/LGALS9/FYN/SOX2/CXCL2/ITGAM/PIM1/DUSP6/IL15RA/IL1RL2/STAT1/IRAK1/RIPK2/IL20RB/MUC1/TEC/PTPN9/JUNB/MAP3K8/IL15/PSMC4/TIMP1/BATF/NFKBIB/SQSTM1/CDKN1A/AKT1/JUN/MSN/RORA/MYC/INPPL1/IRAK4/STAT2/MAPKAPK2/RELA/STX4/PTPN11/CCL20/IL27RA/NOD1/CSF2/PAK2/IL6ST/STXBP2/PSMD11/PTPN12/MAP2K1/ALOX5/RALA/CFL1/SYK
REACTOME_GENE_SILENCING_BY_RNA 123 -0.5110819 -1.898076 0.0000056 0.0001240 0.0001022 3700 H2AX/HSP90AA1/H3C6/TDRD1/H2BC6/H4C5/H2BC5/H4C12/NUP37/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/HENMT1/NDC1/H2BC9/H3C11/H3C1/TDRD6/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/MIR23B/H3C10/H2BC7/H2BC3/PIWIL2/H4C13/H4C9/H2BC13/H2AC14/MYBL1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES 446 0.3896559 1.613445 0.0000057 0.0001241 0.0001023 2992 NTRK1/SOCS1/ARC/CD274/NCF1/PTPRO/TRIB3/PCSK6/COL6A1/HBEGF/SGK1/BDNF/PRDM1/ATP6V1C2/KL/FGFR4/ATP6V0D2/FGFBP1/NTRK2/FLT1/IL2RG/EREG/NTRK3/FOS/F3/MAPKAPK3/VEGFA/TNS4/FOSB/DOCK3/FGF2/EGR1/APOE/EGR2/ITPR3/MET/GRB10/KITLG/ANOS1/TRIB1/NRP2/HIF1A/MKNK1/FOSL1/MAPK12/KDR/ATP6V0A2/LAMA4/GAB2/DUSP3/IRS2/ASCL1/YAP1/ID3/AP2B1/SPHK1/KLB/DUSP7/SPRED2/MAPK11/THBS1/KRAS/BCAR1/FYN/DUSP6/AXL/SH2B3/MST1R/JUND/NCF2/ADAP1/ITGAV/AP2M1/LAMB3/SPINT2/STAT1/RAC1/RAB4B/AKT3/TGFA/TEC/JUNB/ATP6V1E2/ACTB/GTF2F2/NRAS/FURIN/PTK6/SPP1/AKT1/LAMB1/ADAM17/MYC/NEDD4/DIAPH1/MAPKAPK2/SHC2/ITGA3/SH3GL1/COL5A2/SRC/PRR5/PTPN11/EPS15/PAK2/PTPN12/MAPK13/MAP2K1/EPS15L1/RALA/ITPR2/ACTG1/TIAM1/FGFBP3/GGA3/LAMA3/VAV2/LAMB2/RAP1A/NCF4/DOCK7/CSK/CAV1/IGF2/ESRP2/AP2A2/PTPN3/ELMO2/SPINT1/CRK/CBL
REACTOME_SIGNALING_BY_NTRKS 123 0.5508215 1.989794 0.0000074 0.0001584 0.0001306 2974 NTRK1/ARC/PTPRO/PCSK6/SGK1/BDNF/NTRK2/NTRK3/FOS/F3/MAPKAPK3/FOSB/DOCK3/EGR1/EGR2/TRIB1/FOSL1/MAPK12/DUSP3/IRS2/ASCL1/ID3/AP2B1/DUSP7/MAPK11/KRAS/FYN/DUSP6/JUND/AP2M1/RAC1/JUNB/NRAS/FURIN/MAPKAPK2/SHC2/SRC/PTPN11/MAPK13/MAP2K1/RALA/TIAM1/RAP1A/AP2A2/CRK
REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS 104 -0.5287602 -1.933478 0.0000084 0.0001753 0.0001445 3967 POLR2I/H2BC12/RBBP4/RBBP7/H3-3A/H2AX/RXRA/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/HOXA1/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/HOXB4/PBX1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP 99 -0.5262306 -1.912968 0.0000085 0.0001753 0.0001445 2162 H2BC9/CDKN2C/H3C11/H3C1/CCNA2/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ANAPC4/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/UBE2C/H3C8/H3C2
REACTOME_RHO_GTPASES_ACTIVATE_PKNS 78 -0.5646956 -1.962463 0.0000099 0.0002024 0.0001668 2162 H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/AR/H3C3/CDC25C/H3C8/H3C2
REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE 46 -0.6384464 -2.023870 0.0000105 0.0002103 0.0001734 3700 H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_HOMOLOGY_DIRECTED_REPAIR 130 -0.4820605 -1.809312 0.0000139 0.0002732 0.0002252 4572 H4C8/RAD50/ATR/LIG3/XRCC1/RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/ERCC4/H2AX/EME1/H2BC6/TIMELESS/H4C5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/WRN/RAD52/H4C6/RAD51B/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CCNA2/CHEK1/DNA2/H2BC11/RPA3/POLE2/H2BC15/BRCA1/H4C4/XRCC2/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/POLQ/H4C13/H4C9/RAD51AP1/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_RHO_GTPASES_ACTIVATE_FORMINS 129 -0.4800147 -1.793853 0.0000144 0.0002780 0.0002291 735 CENPK/DIAPH3/CENPP/KNL1/SGO2/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/BUB1B/SPC25
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS 112 -0.5019533 -1.847652 0.0000159 0.0003033 0.0002499 1665 H2BC9/H3C11/H3C1/H2BC11/H3C13/LMO2/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/GATA2/H2BC10/H3C7/MYB/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_BASE_EXCISION_REPAIR_AP_SITE_FORMATION 53 -0.6185152 -2.033968 0.0000177 0.0003313 0.0002731 4574 H2AC8/H4C8/H2AC6/NEIL1/H2BC8/NEIL2/H2BC12/UNG/H2AX/NTHL1/H2BC6/H4C5/H2BC5/H4C12/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_TELOMERE_MAINTENANCE 100 -0.5141976 -1.871398 0.0000195 0.0003590 0.0002959 4152 H2BC8/PRIM1/POLA1/RPA1/POLR2I/H2BC12/RUVBL1/H3-3A/H2AX/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/POLD1/RFC3/WRAP53/H2AJ/WRN/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/H2BC9/CHTF8/CCNA2/DNA2/H2BC11/RPA3/H2BC15/LIG1/H4C4/H4C1/H2AC4/BLM/POLA2/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/DSCC1/H2BC14/H2BC10/H2BC17
REACTOME_AMYLOID_FIBER_FORMATION 85 -0.5397976 -1.894173 0.0000227 0.0004123 0.0003398 2162 H2BC9/H3C11/H3C1/H2BC11/H3C13/CALB1/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/LTF/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE 20 -0.7733783 -2.048526 0.0000237 0.0004226 0.0003483 871 ANAPC4/CDC14A/CDC20/UBE2C
REACTOME_METABOLISM_OF_STEROIDS 126 0.5279357 1.918570 0.0000317 0.0005580 0.0004598 1035 CYP51A1/MVD/ACAT2/HMGCS1/EBP/FDPS/ELOVL6/LSS/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/SLCO1B1/STARD4/HELZ2/FDFT1/SQLE/SCD/NSDHL/SC5D/STARD5/FASN/SRD5A3/TM7SF2/CYP27B1/MVK/HSD17B12/SLCO1B3
REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING 89 0.5704236 1.983418 0.0000351 0.0006089 0.0005018 2342 NOS2/SOCS1/IL13RA2/ALOX15/MMP1/MAOA/CXCL8/CCL22/CD36/IL2RG/FOS/BCL2/VEGFA/IL1A/FGF2/GATA3/ANXA1/HIF1A/PTGS2/IL23A/ICAM1/TNF/SOCS3/HMOX1/LIF/IL4R/SOX2/ITGAM/PIM1/STAT1/MUC1/JUNB/TIMP1/BATF/CDKN1A/AKT1/RORA/MYC
REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS 85 -0.5342726 -1.874786 0.0000366 0.0006250 0.0005151 918 FBXO5/ANAPC4/CCNB1/PTTG1/CDC14A/MAD2L1/NEK2/PLK1/CDK1/CDC20/UBE2C/BUB1B
REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS 92 -0.5235500 -1.865411 0.0000494 0.0008315 0.0006852 4260 RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/H2AX/H2BC6/TIMELESS/H4C5/RAD9B/ATM/H2BC5/H4C12/RFC3/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/CCNA2/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_CELLULAR_SENESCENCE 181 -0.4193726 -1.668964 0.0000704 0.0011673 0.0009621 2162 H2BC9/CDKN2C/H3C11/TFDP2/H3C1/CCNA2/H2BC11/H3C13/MAP2K6/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ANAPC4/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/H1-5/H2BC14/H2BC10/LMNB1/H3C7/H1-1/H2BC17/H3C12/CCNE2/H3C3/UBE2C/H3C8/H3C2
REACTOME_MEIOTIC_SYNAPSIS 62 -0.5705567 -1.904949 0.0001058 0.0017307 0.0014264 4574 H2AC8/H4C8/ATR/H2AC6/H2BC8/STAG2/H2BC12/SYCP2/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SYNE1/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H2BC17
REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES 65 -0.5501950 -1.849551 0.0001132 0.0018250 0.0015041 3239 SUV39H1/RBBP4/RBBP7/H3C6/H4C5/H4C12/KMT5C/SMYD3/H4C6/EZH2/H4C3/H4C2/DPY30/SMYD2/H3C11/H3C1/H3C13/H4C4/H4C1/H3C10/H4C13/H4C9/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_HDMS_DEMETHYLATE_HISTONES 45 -0.6149784 -1.942451 0.0001160 0.0018445 0.0015202 2521 H4C3/H4C2/H3C11/H3C1/H3C13/H4C4/H4C1/H3C10/H4C13/H4C9/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_NOTCH 217 -0.3967567 -1.603549 0.0001349 0.0021169 0.0017447 2019 NOTCH3/H3C11/TFDP2/DLL1/H3C1/PBX1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/HEY1/H3C10/NBEA/H2BC7/H2BC3/H4C13/HEY2/H4C9/PLXND1/ATP2A3/NEURL1/H2BC13/H2AC14/E2F1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/ST3GAL6/MIR449C/HEYL/H3C3/DLGAP5/H3C8/H3C2
REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION 134 -0.4540423 -1.712717 0.0001427 0.0022086 0.0018202 2866 H4C6/ERBB4/H2BC4/ESR1/H2AZ2/TFF3/H4C3/H4C2/H2BC9/H3C11/H3C1/CXXC5/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/MYB/H2BC17/H3C12/NR5A2/H3C3/H3C8/H3C2
REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE 58 -0.5750387 -1.902840 0.0001538 0.0023491 0.0019361 3967 H2AC8/H4C8/H2AC6/H2BC8/POLR2I/H2BC12/H3-3A/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17
REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE 111 -0.4762203 -1.749237 0.0001636 0.0024346 0.0020065 3030 H2AJ/MAPK10/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/CDKN2C/H3C11/TFDP2/H3C1/H2BC11/H3C13/MAP2K6/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_G2_M_CHECKPOINTS 160 -0.4274524 -1.656697 0.0001622 0.0024346 0.0020065 3582 MCM2/H2BC6/H4C5/RAD9B/ATM/H2BC5/MCM7/H4C12/RFC3/CHEK2/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/CDC7/MCM8/PKMYT1/ABRAXAS1/CDC25A/BLM/BRIP1/H2BC7/H2BC3/CCNB1/ORC1/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/CCNB2/H2BC17/CDK1/MCM10/GTSE1/CDC25C
REACTOME_CHROMATIN_MODIFYING_ENZYMES 255 -0.3805885 -1.552443 0.0001719 0.0025262 0.0020820 4713 RPS2/ENY2/ARID4A/HDAC2/SETD6/NSD3/H2AC8/H4C8/KDM3B/KDM4D/H2AC6/CHD4/EED/PRMT7/H2BC8/H2BC18/MSL3/MCRS1/KDM3A/MORF4L1/SUV39H1/H2BC12/KAT2A/RBBP4/SUDS3/EP400/RUVBL1/RBBP7/ACTL6A/ELP6/H2AX/H3C6/H2BC6/H4C5/SMARCA2/SMARCE1/H2BC5/H4C12/RUVBL2/HAT1/KMT5C/WDR77/H2AJ/SMYD3/SAP30/H4C6/H2BC4/ING4/H2AZ2/EZH2/H4C3/H4C2/JADE1/DPY30/H2BC9/SMYD2/PADI1/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/PADI2/H4C1/H2AC4/H3C10/H2AC16/H2BC7/SMARCD3/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ 63 -0.5518790 -1.855374 0.0001890 0.0027423 0.0022601 3762 TDP1/XRCC4/XRCC5/H4C8/RAD50/H2BC8/H2BC12/TP53BP1/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/H4C6/H2BC4/BARD1/H4C3/H4C2/MRE11/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2BC14/H2BC10/H2BC17
REACTOME_HCMV_EARLY_EVENTS 117 -0.4641200 -1.724741 0.0002180 0.0031243 0.0025749 2260 NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION 24 -0.6913693 -1.913010 0.0002440 0.0034549 0.0028473 1178 CCNA2/PKMYT1/CDC25A/CCNB1/FOXM1/CCNB2/PLK1/CDK1/CDC25C
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION 90 -0.5004047 -1.787646 0.0002726 0.0038135 0.0031429 5794 RPLP0/RPL26L1/RPL17/RPS11/RPL19/RPS16/RPL12/RPL10/RPS28/RPS27A/RPS9/RPS10/RPL27/EEF2/RPL39/RPS19/RPS3/RPSA/RPL41/RPL9/RPL7A/RPL37A/RPS27/RPS2/RPS29/RPS24/EEF1A1/EEF1B2/RPS5/RPS8/RPS15A/RPL36A/RPS21/RPS20/RPL34/RPL13/RPL24/RPS13/RPS12/RPL23A/RPS7/RPS23/RPL27A/RPL3/RPL32/RPL30/RPL29/RPL21/RPL31/RPL14/RPL13A/RPS6/RPL6/RPS14/RPL11/RPL37/RPS25/RPL35A/RPL22/RPL7/RPS18/RPL23/RPL4/RPS4X/RPL10A/RPS4Y1/RPL39L/RPL26/RPL15/RPL5/RPS3A
REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION 81 -0.5133707 -1.795911 0.0002831 0.0039127 0.0032247 2866 H4C6/H2BC4/H2AZ2/H4C3/H4C2/DPY30/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR 159 -0.4190631 -1.624098 0.0003693 0.0050441 0.0041571 4815 TDP1/RAD51/XRCC4/XRCC5/H4C8/RAD50/ATR/LIG3/XRCC1/RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/ERCC4/H2AX/EME1/H2BC6/TIMELESS/H4C5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/CHEK2/WRN/RAD52/H4C6/RAD51B/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CCNA2/CHEK1/DNA2/H2BC11/RPA3/POLE2/H2BC15/BRCA1/H4C4/XRCC2/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/POLQ/H4C13/H4C9/RAD51AP1/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE 70 -0.5354568 -1.827494 0.0004090 0.0055214 0.0045504 3961 H2AC8/H4C8/RAD50/CDKN1B/H2AC6/H2BC8/H2BC12/EP400/H1-3/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MRE11/H2BC9/CCNA2/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H1-5/H2BC14/H2BC10/LMNB1/H1-1/H2BC17/CCNE2
REACTOME_ION_CHANNEL_TRANSPORT 137 0.4580825 1.674726 0.0004391 0.0058597 0.0048293 1982 ANO1/TRPV6/TRPM6/ATP12A/CASQ2/SLC9B2/SGK1/TTYH2/ANO2/ATP6V1C2/SLC9B1/ATP6V0D2/CLIC2/ANO4/STOM/SCNN1D/FXYD6/RIPK3/ATP11A/ANO8/TRPV3/ATP6V0A2/ATP8B1/ATP13A5/ATP8A2/CLCN6/TRPM4/ANO7/FKBP1B/ATP1B1/TPCN2/MLKL/ATP13A2/ANO9/RYR3/ATP6V1E2
REACTOME_INTERLEUKIN_1_SIGNALING 99 0.4995373 1.738477 0.0005533 0.0072690 0.0059908 5127 IL1R2/NOD2/IL1A/NFKB2/IL1RN/IRAK2/NFKBIA/MYD88/PSMA6/IRAK1/RIPK2/MAP3K8/PSMC4/NFKBIB/SQSTM1/IRAK4/RELA/NOD1/PSMD11/MAP2K1/PSMD7/IKBKG/PSMB2/PSMD3/PELI3/NKIRAS2/PSMB8/PSMD14/PSMC1/TOLLIP/PSMA2/TNIP2/PSMB9/PSMD1/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PELI1/PSMD13/SEM1/PSMB7/PSMD2/SAA1/PSME4/PSMA3
REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING 117 0.4800937 1.719816 0.0005572 0.0072690 0.0059908 5127 RASGRP1/LAT2/PRKCQ/FOS/ITPR3/NFKBIA/CARD11/PSMA6/GAB2/KRAS/FYN/RAC1/TEC/PSMC4/NRAS/BCL10/JUN/RELA/PAK2/PSMD11/ITPR2/SYK/VAV2/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/LYN/MALT1/PSMD1/PLCG1/CDC34/PSMB6/TAB3/PSMD8/PIK3CB/MAPK1/PSME3/MAPK3/TAB2/SHC1/PSME2/GRB2/PSMF1/PSMA7/HRAS/PSMC5/MAPK9/PSMD12/NFKB1/PSMD9/PAK1/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3
REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC 25 0.6937737 1.863579 0.0006125 0.0079018 0.0065123 4292 TAP2/TAP1/SEC23A/SEC13/HLA-F/HLA-C/SEC31A/TAPBP/SEC24D/HLA-G/HLA-A/CALR/SEC24A/HLA-B/SEC24C/HLA-E/HSPA5/ERAP1/PDIA3/ERAP2
REACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING 10 0.8484964 1.858584 0.0008057 0.0102112 0.0084156 1080 CD274/PRDM1/IL2RG/HIF1A
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 175 0.4333897 1.637975 0.0008092 0.0102112 0.0084156 2497 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC5A1/SLC39A8/SLC2A6/SLC24A3/SLC5A8/SLC7A11/SLCO4A1/SLCO1B1/SLC6A14/SLC3A2/SLC29A2/SLC7A9/SLC12A2/SLC7A5/SLC7A1/SLC28A3/SLC1A5/SLC5A3/SLC4A9/SLC36A1/SLCO1B3/SLC26A6/SLC26A11/SLC1A4/SLCO3A1/SLC27A4/SLC4A3/SLC38A1/SLCO4C1/AHCYL2/SLC15A3/SLC5A12/SLC12A4/SLC35C1/SLC39A1/SLC16A7/SLC9A1/SLC6A9/SLC17A5/SLC9A4/SLC8A1/SLC8B1/SLC39A4/SLC16A3/SLC39A14/SLC35D2/SLC25A22/SLC35B4/SLC39A7/SLC6A11/SLC29A4/SLC20A2/SLC50A1/RUNX1/SLC9A7
REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 24 0.6969385 1.849807 0.0008416 0.0105070 0.0086594 1486 WARS1/GARS1/MARS1/YARS1/AARS1/TARS1/IARS1/SARS1/EPRS1
REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE 72 -0.5048914 -1.732447 0.0008664 0.0105883 0.0087264 3762 TP53BP1/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/CHEK2/H4C6/H2BC4/BARD1/H4C3/H4C2/MRE11/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2BC14/H2BC10/H2BC17
REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 109 0.4797223 1.712708 0.0008574 0.0105883 0.0087264 3274 PHOSPHO1/PLA2G3/PNPLA3/ACHE/LPIN1/MFSD2A/PLA2G4C/ABHD4/PLAAT1/LIPH/PLA2G4A/GPCPD1/GPAT3/LPCAT4/GPD2/PISD/PTPMT1/SELENOI/CPNE3/GPAT4/TAFAZZIN/CSNK2B/ACP6/MBOAT1/PLD2/PTDSS1/LPIN2/PITPNM2/PITPNB/LPIN3/ABHD3/OSBPL5/MIGA2/PLA2G15/MGLL/PNPLA2/AGPAT3
REACTOME_CILIUM_ASSEMBLY 184 -0.3809081 -1.512139 0.0008827 0.0106752 0.0087980 3775 CEP57/UNC119B/HAUS1/ARL6/CEP41/TCTN1/HSP90AA1/IFT20/CEP250/TUBA4B/CEP164/CEP43/IQCB1/KIF3A/ARL13B/DYNLT2B/IFT46/BBS10/CEP135/IFT22/ARL3/DYNC2I1/BBS9/CLUAP1/TMEM216/BBIP1/IFT122/IFT43/TCTN2/BBS2/CNTRL/WDR19/CENPJ/KIF17/KIF24/DYNC2LI1/TMEM67/B9D1/PCM1/CEP83/CEP76/CEP97/CCP110/IFT57/IFT140/CEP162/IFT27/CC2D2A/IFT88/IFT52/IFT74/NPHP1/BBS12/CNGA4/CETN2/IFT81/RPGRIP1L/WDR35/IFT172/IFT80/DYNC2H1/MKS1/B9D2/DYNLT2/LZTFL1/CEP78/CEP70/BBS4/DYNLRB2/TTC21B/PRKAR2B/NEK2/PLK1/PLK4/CDK1
REACTOME_SYNTHESIS_OF_PC 25 0.6739735 1.810392 0.0010740 0.0128545 0.0105941 439 PHOSPHO1/ACHE/LPIN1/MFSD2A
REACTOME_TRYPTOPHAN_CATABOLISM 12 0.8131124 1.859454 0.0011985 0.0141985 0.0117017 709 IDO2/KYAT1/HAAO/IDO1/SLC3A2/SLC7A5
REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS 49 0.5925193 1.851894 0.0013214 0.0154969 0.0127718 1907 B3GNT6/GCNT3/MUC21/GALNT4/MUC3A/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ST3GAL4/B3GNT8/MUC1/MUC4
REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION 74 0.5224813 1.763508 0.0013488 0.0156591 0.0129055 6112 RASGRP1/PRKCQ/NFKBIA/CARD11/PSMA6/PSMC4/BCL10/RELA/PSMD11/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/LYN/MALT1/PSMD1/CDC34/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3/PSMA1/UBC/UBE2D2/BTRC/TAB1/PSMC3/TRAF6/IKBKB/UBE2V1/PDPK1
REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS 73 -0.4827062 -1.657787 0.0015438 0.0177459 0.0146254 1585 GSTM2/SULT1E1/GSTM1/UGT1A7/UGT1A5/UGT3A2/SULT1B1/SLC26A1/ACSM1/GSTA3/UGT1A8/NAT1/GSTA4/UGT2A1/GSTA1/GSTA2
REACTOME_INTERLEUKIN_10_SIGNALING 33 0.6524401 1.890235 0.0017235 0.0196176 0.0161679 1546 IL1R2/CXCL10/CCL4/CXCL8/CCL22/IL1A/CD86/IL1RN/PTGS2/CXCL1/ICAM1/TNF/LIF/PTAFR/CCL5/CXCL2
REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 78 0.5137581 1.752965 0.0017550 0.0197823 0.0163036 1831 SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC24A3/SLC5A8/SLC7A11/SLC6A14/SLC3A2/SLC7A9/SLC12A2/SLC7A5/SLC7A1/SLC1A5/SLC4A9/SLC36A1/SLC26A6/SLC26A11/SLC1A4/SLC4A3/SLC38A1/AHCYL2/SLC15A3/SLC5A12/SLC12A4/SLC9A1/SLC17A5/SLC9A4/SLC8A1/SLC8B1
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 130 -0.4092749 -1.536127 0.0018198 0.0203156 0.0167432 1642 H3C13/KIF19/KIF22/KIF18A/PRKACB/KIF26B/KIF11/H3C10/KIFC1/KIF21A/KIF4A/PRKAR2B/KIF20B/GATA2/H3C7/MYB/H3C12/CENPE/KIF15/KIF2C/KIF20A/H3C3/HBB/KIF18B/H3C8/H3C2
REACTOME_DISEASES_OF_DNA_REPAIR 34 -0.6007858 -1.786260 0.0018579 0.0204501 0.0168540 3602 MUTYH/RAD51/RAD50/NEIL1/RMI1/MSH6/NTHL1/ATM/BRCA2/WRN/OGG1/MSH2/RAD51B/BARD1/MSH3/MRE11/DNA2/BRCA1/XRCC2/BLM/BRIP1/RAD51AP1/EXO1/NEIL3
REACTOME_STIMULI_SENSING_CHANNELS 79 0.5027272 1.720954 0.0018671 0.0204501 0.0168540 1936 ANO1/TRPV6/TRPM6/CASQ2/SLC9B2/SGK1/TTYH2/ANO2/SLC9B1/CLIC2/ANO4/STOM/SCNN1D/RIPK3/ANO8/TRPV3/CLCN6/TRPM4/ANO7/FKBP1B/TPCN2/MLKL/ANO9/RYR3
REACTOME_TRNA_AMINOACYLATION 41 0.5901755 1.795637 0.0019425 0.0208816 0.0172096 1486 WARS1/GARS1/MARS1/YARS1/AARS1/TARS1/IARS1/SARS1/EPRS1
REACTOME_HCMV_INFECTION 141 -0.4072971 -1.552144 0.0019337 0.0208816 0.0172096 2260 NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE 42 -0.5554177 -1.727075 0.0020411 0.0217401 0.0179172 4547 RAD50/ATR/RAD9A/TOPBP1/RPA1/RMI1/RAD9B/ATM/BRCA2/RFC3/WRN/RAD51B/BARD1/RFC5/MRE11/CHEK1/DNA2/RPA3/BRCA1/XRCC2/BLM/BRIP1/RAD51AP1/EXO1
REACTOME_SIGNALLING_TO_RAS 19 0.7315494 1.847913 0.0021248 0.0224261 0.0184826 2689 NTRK1/MAPKAPK3/MAPK12/MAPK11/KRAS/NRAS/MAPKAPK2/SHC2/SRC/MAPK13/RALA
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 110 -0.4337667 -1.589391 0.0021643 0.0226379 0.0186571 5794 RPLP0/RPL26L1/RPL17/RPS11/RPL19/RPS16/RPL12/RPL10/RPS28/RPS27A/RPS9/RPS10/RPL27/SRP14/RPL39/RPS19/RPS3/RPSA/RPL41/RPL9/RPL7A/RPL37A/RPS27/RPS2/RPS29/RPS24/RPS5/RPS8/RPS15A/RPL36A/RPS21/RPS20/RPL34/RPL13/RPL24/RPS13/RPS12/RPL23A/RPS7/RPS23/RPL27A/RPL3/RPL32/RPL30/RPL29/RPL21/RPL31/RPL14/RPL13A/RPS6/RPL6/RPS14/RPL11/RPL37/RPS25/RPL35A/RPL22/SRP9/RPL7/RPS18/RPL23/RPL4/RPS4X/RPL10A/RPS4Y1/RPL39L/SRPRB/RPL26/RPL15/RPL5/RPS3A
REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA 37 -0.5773343 -1.764814 0.0022149 0.0227569 0.0187552 4801 RAD51/RAD50/ATR/RAD9A/TOPBP1/RPA1/RMI1/ERCC4/RAD9B/ATM/RFC3/WRN/RAD52/BARD1/RFC5/MRE11/ERCC1/DNA2/RPA3/BRCA1/BLM/BRIP1/EXO1
REACTOME_DNA_REPAIR 319 -0.3327307 -1.390761 0.0022071 0.0227569 0.0187552 4094 NEIL2/RPA1/MCRS1/ERCC5/POLR2I/H2BC12/RMI1/UNG/RUVBL1/ACTL6A/TP53BP1/ERCC4/H2AX/EME1/MSH6/NTHL1/H2BC6/TIMELESS/MGMT/H4C5/FANCL/GTF2H5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/ALKBH2/CHEK2/H2AJ/WRN/RAD52/OGG1/MSH2/H4C6/RAD51B/FANCM/H2BC4/BARD1/H2AZ2/MSH3/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CENPS/CETN2/CCNA2/CHEK1/DNA2/FANCI/H2BC11/RPA3/POLE2/POLI/H2BC15/LIG1/BRCA1/H4C4/XRCC2/UBE2T/H4C1/H2AC4/FANCB/ABRAXAS1/BLM/POLN/BRIP1/H2BC7/H2BC3/INO80B/POLQ/H4C13/FTO/H4C9/CHD1L/RAD51AP1/H2BC13/EXO1/H2AC14/PCLAF/H2BC14/H2BC10/H2BC17/DTL/NEIL3
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION 228 0.3775087 1.475147 0.0022916 0.0233385 0.0192345 2514 CAPN14/EMILIN2/VWF/LOXL4/MMP1/ITGA10/COL6A1/COL13A1/SDC2/KLK7/ADAMTS14/CD44/ADAM8/MMP16/LUM/NID2/CAPN12/TNC/MMP19/SDC3/FGF2/CD47/MMP25/MATN3/ADAM9/PXDN/MMP17/COLGALT2/TIMP2/CEACAM1/ITGB8/KDR/ICAM1/LAMA4/DDR2/ADAMTS9/ITGA9/BMP2/MMP11/THBS1/COL22A1/ITGA6/ITGAM/LOX/COL17A1/SERPINH1/MMP10/ITGAV/LAMB3/PLOD3/COLGALT1/BMP1/COL14A1/LTBP4/ITGB7/TIMP1/ITGB6/FURIN/CAPN2/SPP1/LAMB1/ADAM17/P4HA2/ITGA3/CD151/PLEC/COL5A2/ACTN1
REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS 13 0.7712075 1.801150 0.0025030 0.0250520 0.0206467 2 NTRK1
REACTOME_G0_AND_EARLY_G1 27 -0.6303936 -1.788322 0.0024834 0.0250520 0.0206467 2188 LIN9/TFDP2/CCNA2/CDC25A/E2F1/CCNE2/CDK1/TOP2A/MYBL2
REACTOME_SIGNALLING_TO_ERKS 32 0.6490895 1.873176 0.0026349 0.0261467 0.0215489 4622 NTRK1/MAPKAPK3/MAPK12/MAPK11/KRAS/NRAS/MAPKAPK2/SHC2/SRC/MAPK13/MAP2K1/RALA/RAP1A/CRK/MAP2K2/KIDINS220/MAPK1/RIT1/MAPK3/RALB/SHC1/GRB2/HRAS
REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS 62 0.5277129 1.720474 0.0031192 0.0306895 0.0252929 914 LY6G6C/THY1/RAET1L/LYPD1/PLAUR/NTNG1/RAET1G/ALPL/CEACAM5/LY6K/ULBP2
REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING 126 0.4418600 1.605762 0.0032467 0.0316762 0.0261061 5127 IL1R2/IL1RL1/IL36G/NOD2/IL36A/IL1A/NFKB2/IL1RN/IL18R1/IRAK2/NFKBIA/MYD88/PSMA6/IL1RL2/IRAK1/RIPK2/PTPN9/MAP3K8/PSMC4/NFKBIB/SQSTM1/IRAK4/RELA/PTPN11/NOD1/PSMD11/PTPN12/MAP2K1/ALOX5/PSMD7/IKBKG/PSMB2/PSMD3/PELI3/NKIRAS2/PTPN23/PSMB8/PSMD14/PSMC1/IL18BP/TOLLIP/PSMA2/TNIP2/PSMB9/PTPN18/PSMD1/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PELI1/PSMD13/SEM1/PSMB7/PSMD2/SAA1/PSME4/PSMA3
REACTOME_NICOTINAMIDE_SALVAGING 16 0.7399894 1.788946 0.0033290 0.0322083 0.0265445 3132 SLC5A8/NNMT/PARP9/PTGS2/NAMPT/PARP14/PARP10/PARP6/NAPRT/PARP4
REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION 13 0.7585417 1.771569 0.0034616 0.0329423 0.0271495 9 NOS2
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 53 0.5411698 1.710513 0.0034433 0.0329423 0.0271495 2943 NOD2/AIM2/BCL2/NFKB2/IRAK2/MAPK12/HMOX1/MAPK11/CARD9/TXN/IRAK1/RIPK2/TNFAIP3/RELA/CYLD/NOD1/BIRC3/MAPK13/IKBKG/CASP2
REACTOME_HYALURONAN_METABOLISM 14 0.7566294 1.781890 0.0036892 0.0348227 0.0286992 757 HAS2/HYAL1/CEMIP/CD44/HAS3/HYAL3
REACTOME_RAB_REGULATION_OF_TRAFFICKING 115 0.4459277 1.597028 0.0039039 0.0365520 0.0301245 5503 DENND4A/RIC1/RAB32/RAB8B/RAB31/OPTN/RINL/TBC1D24/DENND5A/AKT3/TBC1D14/RAB9A/RAB35/TBC1D10A/DENND3/AKT1/DENND4C/RAB6A/HPS1/RAB5B/GGA3/RGP1/TBC1D20/TBC1D16/MON1A/RAB3IP/TRAPPC10/CCZ1/TSC1/MAP1LC3B/TRAPPC6A/TBC1D10B/RAB8A/RAB11A/RAB3A/MON1B/RAB21/RABGAP1/ANKRD27/ARF6/RAB5C/RAB7A/TBC1D7/SBF1/CCZ1B/DENND2C/SYTL1/RAB10/TBC1D25/DENND5B/RAB14/RAB18/RAB5A/DENND4B/GGA2/DENND1A/RAB3GAP2/TRAPPC12/SBF2/RAB27A/RAB12/GDI1/RAB1A/RABEP1/TBC1D13/TRAPPC2/ULK1/TRAPPC1/RAB33B/MADD/TRAPPC9
REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION 14 -0.7221659 -1.732056 0.0040090 0.0368576 0.0303763 867 CCNB1/CCNB2/PLK1/CDK1
REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY 69 0.5042976 1.681852 0.0040318 0.0368576 0.0303763 5850 DLX5/PPARGC1B/RUNX2/MSX2/PSMA6/BMP2/STAT1/PSMC4/PSMD11/HIVEP3/PPARGC1A/PSMD7/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/PSMD1/PSMB6/PSMD8/PSME3/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/GSK3B/PSMD9/STUB1/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3/PSMA1/CBFB/UBC/WWP1/TWIST1/ESRRA/PSMC3
REACTOME_BIOLOGICAL_OXIDATIONS 158 -0.3846918 -1.489908 0.0040049 0.0368576 0.0303763 1934 UGT1A4/CYP4B1/CYP27A1/PTGS1/GSTM2/SULT1E1/GSTM1/ALDH2/ADH7/ALDH1A1/UGT1A7/CYP2C8/UGT1A5/UGT3A2/CYP2W1/FMO3/SULT1B1/CYP4F3/CYP39A1/MTARC1/SLC26A1/ACSM1/ACSS1/GSTA3/POMC/EPHX1/CYP24A1/DPEP2/CYP2B6/UGT1A8/NAT1/CYP2F1/ADH6/CYP4A22/FMO2/CYP2A6/ALDH3A1/GSTA4/CYP26B1/UGT2A1/GSTA1/GSTA2
REACTOME_METALLOPROTEASE_DUBS 30 -0.5918390 -1.718189 0.0041518 0.0376580 0.0310360 2089 STAMBPL1/BARD1/H2AC15/BRCA1/H2AC4/ABRAXAS1/H2AC16/H2AC13/H2AC11/H2AC21/H2AC14/H2AC12
REACTOME_BASIGIN_INTERACTIONS 20 0.6926358 1.770445 0.0042623 0.0380153 0.0313304 2847 MMP1/SLC7A11/SLC3A2/SLC7A9/SLC7A5/ITGA6/ATP1B1/SLC16A3/ITGA3/CAV1
REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 80 0.4940431 1.699162 0.0042894 0.0380153 0.0313304 2634 MX2/ISG15/OAS3/OASL/OAS1/MX1/IFIT1/USP18/OAS2/UBE2L6/HERC5/STAT1/EIF2AK2/TRIM25/NUP188/EIF4E3/SEC13/NEDD4/EIF4G1/PDE12
REACTOME_PHOSPHOLIPID_METABOLISM 185 0.3974143 1.510926 0.0042298 0.0380153 0.0313304 4865 PHOSPHO1/PLA2G3/PNPLA3/ACHE/LPIN1/MFSD2A/PLA2G4C/ABHD4/ENPP6/PLAAT1/LIPH/PLA2G4A/GPCPD1/GPAT3/LPCAT4/GPD2/PISD/PLEKHA6/PTPMT1/SELENOI/CPNE3/PLEKHA2/GPAT4/PIP4K2A/TAFAZZIN/CSNK2B/ACP6/GDPD3/PIP5K1A/MBOAT1/PIK3C2B/PLD2/MTMR12/INPPL1/PTDSS1/PIP4P1/LPIN2/PITPNM2/PITPNB/LPIN3/ABHD3/OSBPL5/INPP5J/MIGA2/PIP4K2C/PLA2G15/PI4K2A/MGLL/ARF3/INPP5F/PLEKHA5/PNPLA2/AGPAT3/INPP5D/CPNE1/PIP5K1C/SYNJ1/HADHA/PIK3CB/SBF1/LPCAT1/DGAT1/PLAAT3/RAB14/MBOAT7/SYNJ2/OCRL/PCYT2/GDE1/RAB5A/OSBPL8/PLEKHA1/PCYT1A/CSNK2A2/DDHD2/STARD10/ARF1/PIKFYVE/INPP5K/PNPLA6/AGPAT2/PNPLA8/CSNK2A1/SBF2/PI4KB
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE 69 0.4996181 1.666245 0.0043886 0.0385996 0.0318120 1281 SPRR2E/RPTN/SPRR3/SPRR2F/SPRR2A/KRT16/PCSK6/SPRR1A/KRT23/KRT24/SPRR2D/KRT40/CSTA/KLK12/KRT6A/KRT78/PI3/LCE1E/KRT8/PKP2/KRT18/PRSS8
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION 147 -0.3890603 -1.490909 0.0044521 0.0388641 0.0320300 2188 LIN9/CDKN2C/TFDP2/CCNA2/TK1/DHFR/RPA3/POLE2/CDC7/MCM8/TYMS/CDC25A/POLA2/FBXO5/CCNB1/ORC1/E2F1/E2F2/CDT1/GMNN/CCNE2/CDK1/RRM2/MCM10/TOP2A/MYBL2
REACTOME_O_LINKED_GLYCOSYLATION 85 0.4765247 1.658298 0.0045608 0.0395158 0.0325671 1907 B3GNT6/GCNT3/THSD7A/MUC21/ADAMTS14/GALNT4/MUC3A/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ADAMTSL3/ADAMTS9/ADAMTS17/ST3GAL4/THBS1/B3GNT8/MUC1/MUC4
REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY 15 0.7556324 1.795113 0.0046385 0.0396281 0.0326596 2725 TRIB3/CHAC1/ASNS/DDIT3/ATF4/GRB10/CEBPG/ATF3/EIF2S2/ATF5
REACTOME_PEPTIDE_HORMONE_METABOLISM 53 0.5316861 1.680537 0.0046762 0.0396281 0.0326596 949 DPP4/INHBE/ACHE/MME/KLF4/PAX6/ACE/ANPEP/PLA2G7/STX1A
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 79 0.4790959 1.640059 0.0046645 0.0396281 0.0326596 5127 RASGRP1/NFKBIA/CARD11/PSMA6/KRAS/NFKBIE/PSMC4/NRAS/NFKBIB/BCL10/RELA/PSMD11/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/FKBP1A/PPIA/PSMB9/MALT1/PSMD1/PSMB6/PSMD8/PSME3/RASGRP3/PSME2/PSMF1/PSMA7/HRAS/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3
REACTOME_NGF_STIMULATED_TRANSCRIPTION 36 0.6105726 1.808003 0.0048102 0.0404688 0.0333525 1941 ARC/SGK1/FOS/F3/FOSB/EGR1/EGR2/TRIB1/FOSL1/ASCL1/ID3/JUND/JUNB
REACTOME_SIGNALING_BY_VEGF 99 0.4545217 1.581815 0.0050038 0.0417942 0.0344448 4007 NCF1/TRIB3/FLT1/MAPKAPK3/VEGFA/ITPR3/NRP2/MAPK12/KDR/SPHK1/MAPK11/KRAS/BCAR1/FYN/AXL/NCF2/ITGAV/RAC1/AKT3/ACTB/NRAS/AKT1/MAPKAPK2/SHC2/SRC/PRR5/PAK2/MAPK13/ITPR2/ACTG1/VAV2/NCF4/CAV1/ELMO2/CRK/WASF1/VEGFD/PRKCA/NCKAP1/JUP/PLCG1/ABI1/MTOR/PIK3CB/CYFIP1/CTNNA1
REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE 14 0.7439570 1.752046 0.0051219 0.0424751 0.0350060 1466 SLC18A2/MAOA/STX1A/PPFIA3/SYT1
REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1 10 0.7907963 1.732195 0.0052550 0.0432699 0.0356610 351 DPP4/PAX6
REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES 11 -0.7473337 -1.671638 0.0056947 0.0465606 0.0383731 2332 SMC4/SMC2/CCNB1/CCNB2/NCAPH/CDK1/NCAPG
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 29 -0.5668830 -1.623894 0.0060854 0.0494068 0.0407188 2188 LIN9/TFDP2/TK1/DHFR/TYMS/CDC25A/FBXO5/ORC1/E2F1/CDT1/CDK1/RRM2

All volcano plots

What is in common and what is specific to each conditions?

Venn diagram

Compare all the differentially expressed genes vs control to each other. This plot allows us to know which genes can be found to be perturbed vs control in all conditions as well as those that are specific to one condition or another.

UP in cytokine and DOWN in Cyt + Pit

Now let’s look at the 1878 + 1402 (3280) genes that are common to cytokines and cyto+statin treatments. The hope is to find some that are up in cytokine and down in statin+cyto vs ctrl. There are 11 such genes.

ensembl log2FoldChange protID gene description padj
ENSG00000127324 0.7722139 P19075 TSPAN8 tetraspanin 8 [Source:HGNC Symbol;Acc:HGNC:11855] 0.0000034
ENSG00000204389 0.4229179 P0DMV8 HSPA1A heat shock protein family A (Hsp70) member 1A [Source:HGNC Symbol;Acc:HGNC:5232] 0.0000052
ENSG00000204388 0.3292206 P0DMV9 HSPA1B heat shock protein family A (Hsp70) member 1B [Source:HGNC Symbol;Acc:HGNC:5233] 0.0001072
ENSG00000143416 0.2839050 F8WBA9 SELENBP1 selenium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10719] 0.0003274
ENSG00000111684 0.3140090 Q6P1A2 LPCAT3 lysophosphatidylcholine acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30244] 0.0004849
ENSG00000120885 0.2417066 E5RG36 CLU clusterin [Source:HGNC Symbol;Acc:HGNC:2095] 0.0013359
ENSG00000165698 0.2294103 Q96E40 SPACA9 sperm acrosome associated 9 [Source:HGNC Symbol;Acc:HGNC:1367] 0.0046370
ENSG00000188229 0.1841673 P68371 TUBB4B tubulin beta 4B class IVb [Source:HGNC Symbol;Acc:HGNC:20771] 0.0120342
ENSG00000112584 0.1857274 Q96EK7 FAM120B family with sequence similarity 120B [Source:HGNC Symbol;Acc:HGNC:21109] 0.0147811
ENSG00000174844 0.2440909 E9PG32 DNAH12 dynein axonemal heavy chain 12 [Source:HGNC Symbol;Acc:HGNC:2943] 0.0183313
ENSG00000105655 0.2977650 J3QRY0 ISYNA1 inositol-3-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:29821] 0.0299998

Highlight on volcano plot

Heatmap

Enrichment analysis (Over-representation analysis)

GOBP

GOMF

UP in cytokine and UNCHANGED in Cyt + Piv

There are 377 such genes.

ensembl log2FoldChange protID gene description padj
ENSG00000166165 0.5314293 G3V4N7 CKB creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991] 0.0000000
ENSG00000168497 1.2295751 O95810 CAVIN2 caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690] 0.0000000
ENSG00000169213 1.1584582 P20337 RAB3B RAB3B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9778] 0.0000000
ENSG00000103319 0.5703994 O00418 EEF2K eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615] 0.0000000
ENSG00000018236 1.0424781 A0A024R104 CNTN1 contactin 1 [Source:HGNC Symbol;Acc:HGNC:2171] 0.0000000
ENSG00000113119 1.0424721 D6R986 TMCO6 transmembrane and coiled-coil domains 6 [Source:HGNC Symbol;Acc:HGNC:28814] 0.0000000
ENSG00000178104 0.4879978 A0A8Q3SI65 PDE4DIP phosphodiesterase 4D interacting protein [Source:HGNC Symbol;Acc:HGNC:15580] 0.0000000
ENSG00000240602 0.8456716 AADACP1 arylacetamide deacetylase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:50305] 0.0000000
ENSG00000162598 0.5094775 Q8N0U7 C1orf87 chromosome 1 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:28547] 0.0000000
ENSG00000172292 0.2859239 Q6ZMG9 CERS6 ceramide synthase 6 [Source:HGNC Symbol;Acc:HGNC:23826] 0.0000000
ENSG00000183762 0.4870750 Q96MU8 KREMEN1 kringle containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:17550] 0.0000000
ENSG00000112992 0.4520492 A0A590UJM7 NNT nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863] 0.0000000
ENSG00000123191 0.6788971 P35670 ATP7B ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870] 0.0000001
ENSG00000119801 0.4625321 P62699 YPEL5 yippee like 5 [Source:HGNC Symbol;Acc:HGNC:18329] 0.0000001
ENSG00000183943 0.5343739 A0A024RBU5 PRKX protein kinase cAMP-dependent X-linked catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9441] 0.0000001
ENSG00000251615 0.9528324 novel transcript 0.0000001
ENSG00000197496 0.5423895 O95528 SLC2A10 solute carrier family 2 member 10 [Source:HGNC Symbol;Acc:HGNC:13444] 0.0000001
ENSG00000234965 2.9034690 B8ZZ34 SHISA8 shisa family member 8 [Source:HGNC Symbol;Acc:HGNC:18351] 0.0000002
ENSG00000101333 0.4108437 A0A8I5KW09 PLCB4 phospholipase C beta 4 [Source:HGNC Symbol;Acc:HGNC:9059] 0.0000003
ENSG00000135324 0.6633815 Q96G30 MRAP2 melanocortin 2 receptor accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:21232] 0.0000003
ENSG00000197702 0.2901922 E9PS97 PARVA parvin alpha [Source:HGNC Symbol;Acc:HGNC:14652] 0.0000009
ENSG00000165572 0.6458741 Q86V97 KBTBD6 kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340] 0.0000015
ENSG00000171368 0.3580780 Q4L233 TPPP tubulin polymerization promoting protein [Source:HGNC Symbol;Acc:HGNC:24164] 0.0000015
ENSG00000143842 0.5524710 Q9UN79 SOX13 SRY-box transcription factor 13 [Source:HGNC Symbol;Acc:HGNC:11192] 0.0000029
ENSG00000125944 0.3267595 O43390 HNRNPR heterogeneous nuclear ribonucleoprotein R [Source:HGNC Symbol;Acc:HGNC:5047] 0.0000030
ENSG00000109182 0.5694086 Q9H720 CWH43 cell wall biogenesis 43 C-terminal homolog [Source:HGNC Symbol;Acc:HGNC:26133] 0.0000030
ENSG00000161642 0.4385341 H0YIX3 ZNF385A zinc finger protein 385A [Source:HGNC Symbol;Acc:HGNC:17521] 0.0000034
ENSG00000205213 0.3431324 Q9BXB1 LGR4 leucine rich repeat containing G protein-coupled receptor 4 [Source:HGNC Symbol;Acc:HGNC:13299] 0.0000038
ENSG00000143653 0.4045476 Q8NBX0 SCCPDH saccharopine dehydrogenase (putative) [Source:HGNC Symbol;Acc:HGNC:24275] 0.0000101
ENSG00000099954 1.2485986 B7WPH3 CECR2 CECR2 histone acetyl-lysine reader [Source:HGNC Symbol;Acc:HGNC:1840] 0.0000103
ENSG00000145022 0.4371134 P57738 TCTA T cell leukemia translocation altered [Source:HGNC Symbol;Acc:HGNC:11692] 0.0000150
ENSG00000162627 0.4589388 B7ZC83 SNX7 sorting nexin 7 [Source:HGNC Symbol;Acc:HGNC:14971] 0.0000154
ENSG00000115286 0.6038390 F5H5N1 NDUFS7 NADH:ubiquinone oxidoreductase core subunit S7 [Source:HGNC Symbol;Acc:HGNC:7714] 0.0000181
ENSG00000163349 0.2561880 J3KP92 HIPK1 homeodomain interacting protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:19006] 0.0000253
ENSG00000160953 0.5306918 Q2TAK8 PWWP3A PWWP domain containing 3A, DNA repair factor [Source:HGNC Symbol;Acc:HGNC:29641] 0.0000262
ENSG00000096384 0.2802813 P08238 HSP90AB1 heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258] 0.0000340
ENSG00000063241 0.5257003 K7EKW4 ISOC2 isochorismatase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26278] 0.0000352
ENSG00000198829 2.5525704 Q9BXA5 SUCNR1 succinate receptor 1 [Source:HGNC Symbol;Acc:HGNC:4542] 0.0000386
ENSG00000140740 0.3464066 H3BP04 UQCRC2 ubiquinol-cytochrome c reductase core protein 2 [Source:HGNC Symbol;Acc:HGNC:12586] 0.0000430
ENSG00000181754 0.9055181 Q86WK6 AMIGO1 adhesion molecule with Ig like domain 1 [Source:HGNC Symbol;Acc:HGNC:20824] 0.0000466
ENSG00000130940 0.2633084 K7EQC6 CASZ1 castor zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:26002] 0.0000551
ENSG00000153707 0.8454015 C9J6E4 PTPRD protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668] 0.0000604
ENSG00000126778 0.2856803 Q15475 SIX1 SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10887] 0.0000691
ENSG00000128245 0.3271017 F8WEB6 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta [Source:HGNC Symbol;Acc:HGNC:12853] 0.0000890
ENSG00000180694 0.4714348 Q6YI46 TMEM64 transmembrane protein 64 [Source:HGNC Symbol;Acc:HGNC:25441] 0.0001035
ENSG00000140848 0.3669057 Q96FN4 CPNE2 copine 2 [Source:HGNC Symbol;Acc:HGNC:2315] 0.0001130
ENSG00000139613 0.3009205 Q8TAQ2 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 [Source:HGNC Symbol;Acc:HGNC:11105] 0.0001185
ENSG00000116704 0.4109574 Q9NTN3 SLC35D1 solute carrier family 35 member D1 [Source:HGNC Symbol;Acc:HGNC:20800] 0.0001306
ENSG00000139531 0.5753195 F8VVW9 SUOX sulfite oxidase [Source:HGNC Symbol;Acc:HGNC:11460] 0.0001365
ENSG00000213585 0.2895838 C9JI87 VDAC1 voltage dependent anion channel 1 [Source:HGNC Symbol;Acc:HGNC:12669] 0.0002057
ENSG00000114638 0.4504850 O75841 UPK1B uroplakin 1B [Source:HGNC Symbol;Acc:HGNC:12578] 0.0002372
ENSG00000183580 0.5689314 J3KNM9 FBXL7 F-box and leucine rich repeat protein 7 [Source:HGNC Symbol;Acc:HGNC:13604] 0.0002466
ENSG00000277749 0.5605533 novel transcript, antisense to CCDC33 0.0002620
ENSG00000204711 0.3756934 Q5VTT2 CFAP95 cilia and flagella associated protein 95 [Source:HGNC Symbol;Acc:HGNC:31422] 0.0002882
ENSG00000146006 2.8039319 O43300 LRRTM2 leucine rich repeat transmembrane neuronal 2 [Source:HGNC Symbol;Acc:HGNC:19409] 0.0003391
ENSG00000161547 0.2830043 Q01130 SRSF2 serine and arginine rich splicing factor 2 [Source:HGNC Symbol;Acc:HGNC:10783] 0.0003391
ENSG00000196189 0.4592495 Q9H3S1 SEMA4A semaphorin 4A [Source:HGNC Symbol;Acc:HGNC:10729] 0.0003417
ENSG00000237167 2.3959842 novel transcript 0.0003454
ENSG00000168439 0.2850528 P31948 STIP1 stress induced phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11387] 0.0003577
ENSG00000178741 0.3500495 H3BNX8 COX5A cytochrome c oxidase subunit 5A [Source:HGNC Symbol;Acc:HGNC:2267] 0.0003625
ENSG00000225975 1.1500598 ZNF567-DT ZNF567 divergent transcript [Source:HGNC Symbol;Acc:HGNC:51281] 0.0003728
ENSG00000116117 0.3707165 Q8TEW8 PARD3B par-3 family cell polarity regulator beta [Source:HGNC Symbol;Acc:HGNC:14446] 0.0003798
ENSG00000175216 0.2817219 H0YEK7 CKAP5 cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:HGNC:28959] 0.0004031
ENSG00000126267 0.3043787 A0A494C160 COX6B1 cytochrome c oxidase subunit 6B1 [Source:HGNC Symbol;Acc:HGNC:2280] 0.0004153
ENSG00000127054 0.3444253 E9PIS0 INTS11 integrator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:26052] 0.0004448
ENSG00000137561 1.8424202 P49638 TTPA alpha tocopherol transfer protein [Source:HGNC Symbol;Acc:HGNC:12404] 0.0004462
ENSG00000004478 0.3146526 F5H120 FKBP4 FKBP prolyl isomerase 4 [Source:HGNC Symbol;Acc:HGNC:3720] 0.0004660
ENSG00000155330 0.5584610 Q6PH81 C16orf87 chromosome 16 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:33754] 0.0004751
ENSG00000167074 0.4126554 Q10587 TEF TEF transcription factor, PAR bZIP family member [Source:HGNC Symbol;Acc:HGNC:11722] 0.0004915
ENSG00000231993 1.0741030 EP300-AS1 EP300 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50504] 0.0004929
ENSG00000103266 0.3551918 Q9UNE7 STUB1 STIP1 homology and U-box containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11427] 0.0005278
ENSG00000044524 2.0700728 C9JXA2 EPHA3 EPH receptor A3 [Source:HGNC Symbol;Acc:HGNC:3387] 0.0005591
ENSG00000100033 0.4936859 C9JIW4 PRODH proline dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:9453] 0.0005833
ENSG00000100564 0.5813653 H0YLY9 PIGH phosphatidylinositol glycan anchor biosynthesis class H [Source:HGNC Symbol;Acc:HGNC:8964] 0.0006155
ENSG00000283633 0.6714995 novel transcript 0.0006179
ENSG00000135617 0.5831691 Q9BSG0 PRADC1 protease associated domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16047] 0.0006977
ENSG00000065978 0.2416451 P67809 YBX1 Y-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8014] 0.0007090
ENSG00000176171 0.3254621 Q12983 BNIP3 BCL2 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:1084] 0.0007463
ENSG00000077092 0.2881432 A0A8I5KVN9 RARB retinoic acid receptor beta [Source:HGNC Symbol;Acc:HGNC:9865] 0.0007616
ENSG00000167535 0.4517242 F8VV14 CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:1403] 0.0008271
ENSG00000053770 0.2762471 H0YIY0 AP5M1 adaptor related protein complex 5 subunit mu 1 [Source:HGNC Symbol;Acc:HGNC:20192] 0.0008586
ENSG00000114956 0.3894586 E5KSL5 DGUOK deoxyguanosine kinase [Source:HGNC Symbol;Acc:HGNC:2858] 0.0008600
ENSG00000137824 0.4346881 A0A024R9P6 RMDN3 regulator of microtubule dynamics 3 [Source:HGNC Symbol;Acc:HGNC:25550] 0.0008829
ENSG00000213523 0.4916913 Q9HD15 SRA1 steroid receptor RNA activator 1 [Source:HGNC Symbol;Acc:HGNC:11281] 0.0009149
ENSG00000110075 0.2213544 E9PKG4 PPP6R3 protein phosphatase 6 regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:1173] 0.0010121
ENSG00000164975 0.2895987 Q5T284 SNAPC3 small nuclear RNA activating complex polypeptide 3 [Source:HGNC Symbol;Acc:HGNC:11136] 0.0010759
ENSG00000152234 0.2450486 P25705 ATP5F1A ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823] 0.0011175
ENSG00000120696 0.4320418 Q8WVZ9 KBTBD7 kelch repeat and BTB domain containing 7 [Source:HGNC Symbol;Acc:HGNC:25266] 0.0012187
ENSG00000136828 0.3031791 Q5JS13 RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 [Source:HGNC Symbol;Acc:HGNC:16851] 0.0013049
ENSG00000114978 0.1745049 Q9H8S9 MOB1A MOB kinase activator 1A [Source:HGNC Symbol;Acc:HGNC:16015] 0.0015867
ENSG00000214530 0.3452295 F5H1Z6 STARD10 StAR related lipid transfer domain containing 10 [Source:HGNC Symbol;Acc:HGNC:10666] 0.0016293
ENSG00000119326 0.2944562 Q5JTQ6 CTNNAL1 catenin alpha like 1 [Source:HGNC Symbol;Acc:HGNC:2512] 0.0016542
ENSG00000163541 0.3612675 P53597 SUCLG1 succinate-CoA ligase GDP/ADP-forming subunit alpha [Source:HGNC Symbol;Acc:HGNC:11449] 0.0016787
ENSG00000280010 0.8654297 TEC 0.0017225
ENSG00000158292 0.3995265 Q6NV75 GPR153 G protein-coupled receptor 153 [Source:HGNC Symbol;Acc:HGNC:23618] 0.0017706
ENSG00000115325 1.5526884 Q99704 DOK1 docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990] 0.0018261
ENSG00000140992 0.2424528 H3BNV5 PDPK1 3-phosphoinositide dependent protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:8816] 0.0018717
ENSG00000088682 0.3254735 H3BNT2 COQ9 coenzyme Q9 [Source:HGNC Symbol;Acc:HGNC:25302] 0.0018977
ENSG00000112562 1.9882099 Q9H3U7 SMOC2 SPARC related modular calcium binding 2 [Source:HGNC Symbol;Acc:HGNC:20323] 0.0019489
ENSG00000073282 0.3947707 A0A0S2Z4N5 TP63 tumor protein p63 [Source:HGNC Symbol;Acc:HGNC:15979] 0.0019740
ENSG00000141429 0.3259146 K7EK46 GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4123] 0.0019843
ENSG00000121057 0.3656520 I3NI36 AKAP1 A-kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:367] 0.0020064
ENSG00000085433 0.2363574 E9PN15 WDR47 WD repeat domain 47 [Source:HGNC Symbol;Acc:HGNC:29141] 0.0020941
ENSG00000054965 0.2749881 Q92567 FAM168A family with sequence similarity 168 member A [Source:HGNC Symbol;Acc:HGNC:28999] 0.0021219
ENSG00000013523 0.4971458 Q9UNK9 ANGEL1 angel homolog 1 [Source:HGNC Symbol;Acc:HGNC:19961] 0.0021348
ENSG00000010256 0.3200070 F8WER5 UQCRC1 ubiquinol-cytochrome c reductase core protein 1 [Source:HGNC Symbol;Acc:HGNC:12585] 0.0021489
ENSG00000105053 0.2626875 M0QYA8 VRK3 VRK serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:18996] 0.0022440
ENSG00000127922 0.3235010 A0A087WYU0 SEM1 SEM1 26S proteasome subunit [Source:HGNC Symbol;Acc:HGNC:10845] 0.0023616
ENSG00000174151 0.3917641 Q8N8Q1 CYB561D1 cytochrome b561 family member D1 [Source:HGNC Symbol;Acc:HGNC:26804] 0.0024636
ENSG00000105364 0.4363847 K7ES61 MRPL4 mitochondrial ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:14276] 0.0025180
ENSG00000163170 0.5139271 Q53S33 BOLA3 bolA family member 3 [Source:HGNC Symbol;Acc:HGNC:24415] 0.0025263
ENSG00000130312 0.4784709 M0R226 MRPL34 mitochondrial ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:14488] 0.0026176
ENSG00000243244 1.1165643 Q9Y6Q2 STON1 stonin 1 [Source:HGNC Symbol;Acc:HGNC:17003] 0.0026211
ENSG00000229666 0.8231632 MAST4-AS1 MAST4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40865] 0.0026945
ENSG00000054219 0.3519620 O60449 LY75 lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729] 0.0028525
ENSG00000182628 0.2878620 J3KTC5 SKA2 spindle and kinetochore associated complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28006] 0.0029707
ENSG00000189419 2.6545030 SPATA41 spermatogenesis associated 41 [Source:HGNC Symbol;Acc:HGNC:48613] 0.0029718
ENSG00000101336 1.5351094 H7BXG4 HCK HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] 0.0030636
ENSG00000148143 0.2109643 U3KQU3 ZNF462 zinc finger protein 462 [Source:HGNC Symbol;Acc:HGNC:21684] 0.0033240
ENSG00000160194 0.2988048 P56181 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 [Source:HGNC Symbol;Acc:HGNC:7719] 0.0033667
ENSG00000204370 0.3470264 G3V173 SDHD succinate dehydrogenase complex subunit D [Source:HGNC Symbol;Acc:HGNC:10683] 0.0034632
ENSG00000162738 0.2730973 Q9ULK5 VANGL2 VANGL planar cell polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:15511] 0.0034739
ENSG00000166233 0.1965715 A0A087WT96 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:689] 0.0037118
ENSG00000213619 0.3432937 O75489 NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 [Source:HGNC Symbol;Acc:HGNC:7710] 0.0037641
ENSG00000129990 0.3369458 A0A024R4N8 SYT5 synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513] 0.0037939
ENSG00000107551 0.6985612 Q5T737 RASSF4 Ras association domain family member 4 [Source:HGNC Symbol;Acc:HGNC:20793] 0.0039171
ENSG00000104824 0.2161668 B4DVF8 HNRNPL heterogeneous nuclear ribonucleoprotein L [Source:HGNC Symbol;Acc:HGNC:5045] 0.0040198
ENSG00000174437 0.1750217 A0A0C4DH86 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 [Source:HGNC Symbol;Acc:HGNC:812] 0.0040710
ENSG00000130414 0.2631423 A0A7I2V594 NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 [Source:HGNC Symbol;Acc:HGNC:7684] 0.0041192
ENSG00000104324 0.5942327 E5RJP8 CPQ carboxypeptidase Q [Source:HGNC Symbol;Acc:HGNC:16910] 0.0041978
ENSG00000289003 0.8687899 novel transcript 0.0043041
ENSG00000151468 0.5610692 Q9BQI4 CCDC3 coiled-coil domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23813] 0.0043118
ENSG00000131368 0.4583051 A0A8Q3SHT9 MRPS25 mitochondrial ribosomal protein S25 [Source:HGNC Symbol;Acc:HGNC:14511] 0.0044147
ENSG00000157502 1.3727942 Q5H9M0 PWWP3B PWWP domain containing 3B [Source:HGNC Symbol;Acc:HGNC:26583] 0.0044836
ENSG00000117118 0.2918148 P21912 SDHB succinate dehydrogenase complex iron sulfur subunit B [Source:HGNC Symbol;Acc:HGNC:10681] 0.0046938
ENSG00000117408 0.3197124 O94829 IPO13 importin 13 [Source:HGNC Symbol;Acc:HGNC:16853] 0.0048972
ENSG00000138439 0.3748340 Q6P1L5 FAM117B family with sequence similarity 117 member B [Source:HGNC Symbol;Acc:HGNC:14440] 0.0050889
ENSG00000278535 0.5717511 A0A087WYV4 DHRS11 dehydrogenase/reductase 11 [Source:HGNC Symbol;Acc:HGNC:28639] 0.0051694
ENSG00000143149 0.2839820 ALDH9A1 aldehyde dehydrogenase 9 family member A1 [Source:HGNC Symbol;Acc:HGNC:412] 0.0055712
ENSG00000225733 0.1713428 FGD5-AS1 FGD5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40410] 0.0056092
ENSG00000010017 0.2387391 A0A024QZW3 RANBP9 RAN binding protein 9 [Source:HGNC Symbol;Acc:HGNC:13727] 0.0056370
ENSG00000091483 0.3521120 A0A804HI24 FH fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700] 0.0059862
ENSG00000276023 0.2455916 Q6FI36 DUSP14 dual specificity phosphatase 14 [Source:HGNC Symbol;Acc:HGNC:17007] 0.0063611
ENSG00000124574 0.3433065 Q5T3U5 ABCC10 ATP binding cassette subfamily C member 10 [Source:HGNC Symbol;Acc:HGNC:52] 0.0064079
ENSG00000009780 0.3704439 Q8TAV0 FAM76A family with sequence similarity 76 member A [Source:HGNC Symbol;Acc:HGNC:28530] 0.0064210
ENSG00000117016 1.1372126 Q9UJD0 RIMS3 regulating synaptic membrane exocytosis 3 [Source:HGNC Symbol;Acc:HGNC:21292] 0.0064694
ENSG00000023228 0.1838333 P28331 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 [Source:HGNC Symbol;Acc:HGNC:7707] 0.0064730
ENSG00000114573 0.1874182 P38606 ATP6V1A ATPase H+ transporting V1 subunit A [Source:HGNC Symbol;Acc:HGNC:851] 0.0067619
ENSG00000197565 0.4688232 A0A087WZY5 COL4A6 collagen type IV alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:2208] 0.0068892
ENSG00000164850 1.2412901 A0A024R849 GPER1 G protein-coupled estrogen receptor 1 [Source:HGNC Symbol;Acc:HGNC:4485] 0.0069927
ENSG00000264269 1.8644909 DYM-AS1 DYM antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37046] 0.0071892
ENSG00000147684 0.3323319 Q9Y6M9 NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 [Source:HGNC Symbol;Acc:HGNC:7704] 0.0074224
ENSG00000163141 0.4690494 Q7Z465 BNIPL BCL2 interacting protein like [Source:HGNC Symbol;Acc:HGNC:16976] 0.0078774
ENSG00000166147 0.6511729 P35555 FBN1 fibrillin 1 [Source:HGNC Symbol;Acc:HGNC:3603] 0.0079058
ENSG00000151929 0.2272347 O95817 BAG3 BAG cochaperone 3 [Source:HGNC Symbol;Acc:HGNC:939] 0.0081973
ENSG00000132002 0.1786621 P25685 DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 [Source:HGNC Symbol;Acc:HGNC:5270] 0.0082340
ENSG00000108528 0.2923303 Q02978 SLC25A11 solute carrier family 25 member 11 [Source:HGNC Symbol;Acc:HGNC:10981] 0.0082422
ENSG00000114547 0.6284800 Q9BZX4 ROPN1B rhophilin associated tail protein 1B [Source:HGNC Symbol;Acc:HGNC:31927] 0.0083205
ENSG00000134852 0.1804089 C9JK03 CLOCK clock circadian regulator [Source:HGNC Symbol;Acc:HGNC:2082] 0.0084868
ENSG00000237172 0.3706896 Q6UX72 B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:28714] 0.0085148
ENSG00000054179 1.0512855 Q9Y5L3 ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3364] 0.0086743
ENSG00000171357 1.3408384 Q96LR2 LURAP1 leucine rich adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:32327] 0.0088145
ENSG00000101193 0.2138111 Q9NWU2 GID8 GID complex subunit 8 homolog [Source:HGNC Symbol;Acc:HGNC:15857] 0.0088952
ENSG00000185896 0.2307478 P11279 LAMP1 lysosomal associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6499] 0.0091352
ENSG00000152102 0.2039561 A1KXE4 FAM168B family with sequence similarity 168 member B [Source:HGNC Symbol;Acc:HGNC:27016] 0.0092384
ENSG00000101342 1.5383863 A0PJX2 TLDC2 TBC/LysM-associated domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16112] 0.0095130
ENSG00000242498 0.3348068 Q7Z6K5 ARPIN actin related protein 2/3 complex inhibitor [Source:HGNC Symbol;Acc:HGNC:28782] 0.0096251
ENSG00000187866 0.2697431 Q96E09 PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 [Source:HGNC Symbol;Acc:HGNC:23490] 0.0096328
ENSG00000163344 0.5262614 Q15126 PMVK phosphomevalonate kinase [Source:HGNC Symbol;Acc:HGNC:9141] 0.0096468
ENSG00000167065 0.2175266 F2Z2P2 DUSP18 dual specificity phosphatase 18 [Source:HGNC Symbol;Acc:HGNC:18484] 0.0096706
ENSG00000066583 0.3836834 Q96CN7 ISOC1 isochorismatase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24254] 0.0097487
ENSG00000113790 0.3936094 Q08426 EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3247] 0.0098867
ENSG00000167130 0.4282455 Q86YN1 DOLPP1 dolichyldiphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:29565] 0.0099479
ENSG00000206567 0.5501848 novel transcript 0.0101431
ENSG00000107819 0.2152513 Q9BWM7 SFXN3 sideroflexin 3 [Source:HGNC Symbol;Acc:HGNC:16087] 0.0104139
ENSG00000211584 0.4267344 F8VQX9 SLC48A1 solute carrier family 48 member 1 [Source:HGNC Symbol;Acc:HGNC:26035] 0.0107601
ENSG00000163655 0.2467467 P49915 GMPS guanine monophosphate synthase [Source:HGNC Symbol;Acc:HGNC:4378] 0.0108333
ENSG00000187513 2.3313381 P35212 GJA4 gap junction protein alpha 4 [Source:HGNC Symbol;Acc:HGNC:4278] 0.0110205
ENSG00000140948 0.2337060 A0A590UJW6 ZCCHC14 zinc finger CCHC-type containing 14 [Source:HGNC Symbol;Acc:HGNC:24134] 0.0110490
ENSG00000155008 0.2595101 Q6UXV4 APOOL apolipoprotein O like [Source:HGNC Symbol;Acc:HGNC:24009] 0.0113364
ENSG00000112139 0.4874214 A0A7P0TB62 MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 [Source:HGNC Symbol;Acc:HGNC:19267] 0.0117611
ENSG00000156709 0.3751823 A0A6Q8PF87 AIFM1 apoptosis inducing factor mitochondria associated 1 [Source:HGNC Symbol;Acc:HGNC:8768] 0.0124914
ENSG00000182796 0.4382363 TMEM198B transmembrane protein 198B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:43629] 0.0125738
ENSG00000139266 0.4451854 Q86YJ5 MARCHF9 membrane associated ring-CH-type finger 9 [Source:HGNC Symbol;Acc:HGNC:25139] 0.0126083
ENSG00000170315 0.2183934 J3QS39 UBB ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12463] 0.0129419
ENSG00000205763 0.7465402 RP9P RP9 pseudogene [Source:HGNC Symbol;Acc:HGNC:33969] 0.0129493
ENSG00000108106 0.4781409 K7EM75 UBE2S ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895] 0.0135820
ENSG00000090316 0.2500344 D6RE80 MAEA macrophage erythroblast attacher, E3 ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:13731] 0.0137399
ENSG00000135924 0.1915258 P25686 DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 [Source:HGNC Symbol;Acc:HGNC:5228] 0.0137602
ENSG00000143437 0.2452310 A6NGV6 ARNT aryl hydrocarbon receptor nuclear translocator [Source:HGNC Symbol;Acc:HGNC:700] 0.0140124
ENSG00000103145 0.4566856 I3L1N5 HCFC1R1 host cell factor C1 regulator 1 [Source:HGNC Symbol;Acc:HGNC:21198] 0.0140285
ENSG00000125864 0.8291621 Q12934 BFSP1 beaded filament structural protein 1 [Source:HGNC Symbol;Acc:HGNC:1040] 0.0140285
ENSG00000131174 0.3061548 P24311 COX7B cytochrome c oxidase subunit 7B [Source:HGNC Symbol;Acc:HGNC:2291] 0.0140560
ENSG00000270127 1.2133600 novel transcript 0.0141312
ENSG00000185133 0.8723338 B5MCL8 INPP5J inositol polyphosphate-5-phosphatase J [Source:HGNC Symbol;Acc:HGNC:8956] 0.0143477
ENSG00000144815 0.3666278 A0A994J548 NXPE3 neurexophilin and PC-esterase domain family member 3 [Source:HGNC Symbol;Acc:HGNC:28238] 0.0145615
ENSG00000067606 0.2791032 D6RBD4 PRKCZ protein kinase C zeta [Source:HGNC Symbol;Acc:HGNC:9412] 0.0148851
ENSG00000223813 0.4511626 PRR15-DT PRR15 divergent transcript [Source:HGNC Symbol;Acc:HGNC:55866] 0.0148860
ENSG00000172053 0.2077456 C9J165 QARS1 glutaminyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:9751] 0.0149144
ENSG00000071462 0.2650440 O43709 BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:16405] 0.0154122
ENSG00000104381 0.3333947 A0A6Q8PF20 GDAP1 ganglioside induced differentiation associated protein 1 [Source:HGNC Symbol;Acc:HGNC:15968] 0.0154421
ENSG00000007168 0.1993140 A0A6Q8PFU3 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:8574] 0.0156695
ENSG00000117450 0.2144957 Q06830 PRDX1 peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352] 0.0158095
ENSG00000198894 0.1851224 G3V5J4 CIPC CLOCK interacting pacemaker [Source:HGNC Symbol;Acc:HGNC:20365] 0.0160129
ENSG00000198794 0.3939580 Q8TAC9 SCAMP5 secretory carrier membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:30386] 0.0160129
ENSG00000138279 0.2058719 P20073 ANXA7 annexin A7 [Source:HGNC Symbol;Acc:HGNC:545] 0.0162405
ENSG00000099290 0.2615519 F8W7U3 WASHC2A WASH complex subunit 2A [Source:HGNC Symbol;Acc:HGNC:23416] 0.0167292
ENSG00000152154 0.8057926 Q8NBL3 TMEM178A transmembrane protein 178A [Source:HGNC Symbol;Acc:HGNC:28517] 0.0169832
ENSG00000112110 0.2801488 Q9H0U6 MRPL18 mitochondrial ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:14477] 0.0169969
ENSG00000198722 0.2197112 A0A0U1RRL2 UNC13B unc-13 homolog B [Source:HGNC Symbol;Acc:HGNC:12566] 0.0174151
ENSG00000173406 1.2257575 O75553 DAB1 DAB adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:2661] 0.0174582
ENSG00000182334 2.2463064 Q8WZ94 OR5P3 olfactory receptor family 5 subfamily P member 3 [Source:HGNC Symbol;Acc:HGNC:14784] 0.0174610
ENSG00000100983 0.2569350 A0A2R8Y2X9 GSS glutathione synthetase [Source:HGNC Symbol;Acc:HGNC:4624] 0.0175024
ENSG00000236204 0.7097884 LINC01376 long intergenic non-protein coding RNA 1376 [Source:HGNC Symbol;Acc:HGNC:50637] 0.0176332
ENSG00000071889 0.3419231 Q5HY75 FAM3A FAM3 metabolism regulating signaling molecule A [Source:HGNC Symbol;Acc:HGNC:13749] 0.0177325
ENSG00000088543 0.8152177 C9IYC4 C3orf18 chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837] 0.0179896
ENSG00000196363 0.3164943 V9GYQ5 WDR5 WD repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:12757] 0.0180755
ENSG00000186104 0.4660150 E9PS56 CYP2R1 cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580] 0.0184003
ENSG00000008869 0.1996379 Q9P2D3 HEATR5B HEAT repeat containing 5B [Source:HGNC Symbol;Acc:HGNC:29273] 0.0184215
ENSG00000187091 0.4063924 P51178 PLCD1 phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060] 0.0187484
ENSG00000158301 0.5152275 Q96D09 GPRASP2 G protein-coupled receptor associated sorting protein 2 [Source:HGNC Symbol;Acc:HGNC:25169] 0.0191571
ENSG00000178184 0.3253229 Q9BYG4 PARD6G par-6 family cell polarity regulator gamma [Source:HGNC Symbol;Acc:HGNC:16076] 0.0196822
ENSG00000141556 0.2370618 A0A804HJ32 TBCD tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581] 0.0197220
ENSG00000284968 0.6022887 Novel transcript, antisense to AFF1 0.0198355
ENSG00000236700 2.0748350 LINC01010 long intergenic non-protein coding RNA 1010 [Source:HGNC Symbol;Acc:HGNC:48978] 0.0199376
ENSG00000182544 0.3063449 Q6N075 MFSD5 major facilitator superfamily domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28156] 0.0200495
ENSG00000176485 0.3248231 P53816 PLAAT3 phospholipase A and acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:17825] 0.0204970
ENSG00000141854 0.4536660 Q96FF7 MISP3 MISP family member 3 [Source:HGNC Symbol;Acc:HGNC:26963] 0.0205143
ENSG00000154723 0.2969892 P18859 ATP5PF ATP synthase peripheral stalk subunit F6 [Source:HGNC Symbol;Acc:HGNC:847] 0.0212766
ENSG00000110328 0.3570203 Q58A54 GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488] 0.0213413
ENSG00000149600 0.3873848 V9GY66 COMMD7 COMM domain containing 7 [Source:HGNC Symbol;Acc:HGNC:16223] 0.0224896
ENSG00000176903 0.1982536 Q8ND90 PNMA1 PNMA family member 1 [Source:HGNC Symbol;Acc:HGNC:9158] 0.0225226
ENSG00000101017 0.4756002 P25942 CD40 CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919] 0.0225898
ENSG00000111450 0.2417874 A0A994J599 STX2 syntaxin 2 [Source:HGNC Symbol;Acc:HGNC:3403] 0.0227359
ENSG00000115073 0.2286209 P42025 ACTR1B actin related protein 1B [Source:HGNC Symbol;Acc:HGNC:168] 0.0227866
ENSG00000272462 0.7790838 LINC02980 long intergenic non-protein coding RNA 2980 [Source:HGNC Symbol;Acc:HGNC:56046] 0.0231358
ENSG00000166228 0.2795377 P61457 PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 [Source:HGNC Symbol;Acc:HGNC:8646] 0.0231779
ENSG00000178952 0.2025298 H3BNU3 TUFM Tu translation elongation factor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:12420] 0.0233106
ENSG00000171681 0.1695170 F5H2H9 ATF7IP activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092] 0.0234802
ENSG00000172315 0.2839998 Q96S44 TP53RK TP53 regulating kinase [Source:HGNC Symbol;Acc:HGNC:16197] 0.0235176
ENSG00000152944 0.2652441 Q13503 MED21 mediator complex subunit 21 [Source:HGNC Symbol;Acc:HGNC:11473] 0.0240140
ENSG00000146247 0.1521217 A0A8V8TQM4 PHIP pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673] 0.0243378
ENSG00000129354 0.2264285 Q9Y6Q5 AP1M2 adaptor related protein complex 1 subunit mu 2 [Source:HGNC Symbol;Acc:HGNC:558] 0.0247044
ENSG00000167552 0.1726201 Q71U36 TUBA1A tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766] 0.0247722
ENSG00000275764 0.4570888 novel transcript 0.0253371
ENSG00000126368 0.3323466 P20393 NR1D1 nuclear receptor subfamily 1 group D member 1 [Source:HGNC Symbol;Acc:HGNC:7962] 0.0256838
ENSG00000149925 0.4365645 H3BQN4 ALDOA aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414] 0.0257241
ENSG00000124164 0.2099238 O95292 VAPB VAMP associated protein B and C [Source:HGNC Symbol;Acc:HGNC:12649] 0.0257241
ENSG00000142794 0.4047210 A0A087WUB7 NBPF3 NBPF member 3 [Source:HGNC Symbol;Acc:HGNC:25076] 0.0258309
ENSG00000179094 0.2046278 J3QSH9 PER1 period circadian regulator 1 [Source:HGNC Symbol;Acc:HGNC:8845] 0.0259963
ENSG00000184916 0.2483143 Q9Y219 JAG2 jagged canonical Notch ligand 2 [Source:HGNC Symbol;Acc:HGNC:6189] 0.0263650
ENSG00000076554 0.2796244 E5RFR7 TPD52 tumor protein D52 [Source:HGNC Symbol;Acc:HGNC:12005] 0.0266723
ENSG00000115993 0.1922322 O60296 TRAK2 trafficking kinesin protein 2 [Source:HGNC Symbol;Acc:HGNC:13206] 0.0267194
ENSG00000103549 0.2075582 A0A087WTK2 RNF40 ring finger protein 40 [Source:HGNC Symbol;Acc:HGNC:16867] 0.0268054
ENSG00000180543 0.2953768 Q86VY4 TSPYL5 TSPY like 5 [Source:HGNC Symbol;Acc:HGNC:29367] 0.0268485
ENSG00000127804 0.2404681 Q86W50 METTL16 methyltransferase 16, N6-methyladenosine [Source:HGNC Symbol;Acc:HGNC:28484] 0.0269862
ENSG00000149639 0.2647481 X6R3R3 SOGA1 suppressor of glucose, autophagy associated 1 [Source:HGNC Symbol;Acc:HGNC:16111] 0.0270193
ENSG00000142675 0.2620091 Q53GM7 CNKSR1 connector enhancer of kinase suppressor of Ras 1 [Source:HGNC Symbol;Acc:HGNC:19700] 0.0271850
ENSG00000116459 0.2145795 P24539 ATP5PB ATP synthase peripheral stalk-membrane subunit b [Source:HGNC Symbol;Acc:HGNC:840] 0.0272752
ENSG00000177700 0.2862180 P62875 POLR2L RNA polymerase II, I and III subunit L [Source:HGNC Symbol;Acc:HGNC:9199] 0.0274413
ENSG00000122877 1.5137361 A0A8I5KYI5 EGR2 early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239] 0.0276123
ENSG00000120306 0.2020342 A0A2R8YEW2 CYSTM1 cysteine rich transmembrane module containing 1 [Source:HGNC Symbol;Acc:HGNC:30239] 0.0278073
ENSG00000138029 0.2335914 C9JEY0 HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [Source:HGNC Symbol;Acc:HGNC:4803] 0.0278333
ENSG00000184076 0.2291200 Q9UDW1 UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X [Source:HGNC Symbol;Acc:HGNC:30863] 0.0279095
ENSG00000063587 0.4309685 A6NFS0 ZNF275 zinc finger protein 275 [Source:HGNC Symbol;Acc:HGNC:13069] 0.0279347
ENSG00000173530 0.3101638 Q9UBN6 TNFRSF10D TNF receptor superfamily member 10d [Source:HGNC Symbol;Acc:HGNC:11907] 0.0279532
ENSG00000157881 0.3677235 H0Y9E4 PANK4 pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366] 0.0281776
ENSG00000276116 0.6226300 FUT8-AS1 FUT8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44294] 0.0283490
ENSG00000142784 0.1766403 Q8N5D0 WDTC1 WD and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:29175] 0.0285640
ENSG00000180008 0.1905949 Q8WXH5 SOCS4 suppressor of cytokine signaling 4 [Source:HGNC Symbol;Acc:HGNC:19392] 0.0287362
ENSG00000112146 0.2532648 C9JDZ9 FBXO9 F-box protein 9 [Source:HGNC Symbol;Acc:HGNC:13588] 0.0289102
ENSG00000164258 0.2851910 A0A0S2Z433 NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 [Source:HGNC Symbol;Acc:HGNC:7711] 0.0290305
ENSG00000152767 0.1843975 A0A1B0GV68 FARP1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 [Source:HGNC Symbol;Acc:HGNC:3591] 0.0294424
ENSG00000133313 0.1704496 J3QL02 CNDP2 carnosine dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:24437] 0.0294858
ENSG00000270343 1.8220700 UNGP3 uracil-DNA glycosylase pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:20036] 0.0295342
ENSG00000070882 0.1739802 Q9H4L5 OSBPL3 oxysterol binding protein like 3 [Source:HGNC Symbol;Acc:HGNC:16370] 0.0297288
ENSG00000068489 0.7575901 Q96HE9 PRR11 proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619] 0.0298004
ENSG00000185043 0.1626662 Q99828 CIB1 calcium and integrin binding 1 [Source:HGNC Symbol;Acc:HGNC:16920] 0.0302585
ENSG00000187955 1.8412650 Q05707 COL14A1 collagen type XIV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2191] 0.0303451
ENSG00000173614 0.3552981 Q9HAN9 NMNAT1 nicotinamide nucleotide adenylyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17877] 0.0303835
ENSG00000105197 0.2825597 Q3ZCQ8 TIMM50 translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656] 0.0304611
ENSG00000167770 0.2066894 Q96FW1 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 [Source:HGNC Symbol;Acc:HGNC:23077] 0.0305817
ENSG00000176473 0.3942130 Q64LD2 WDR25 WD repeat domain 25 [Source:HGNC Symbol;Acc:HGNC:21064] 0.0308135
ENSG00000245680 0.2604395 F2Z3L4 ZNF585B zinc finger protein 585B [Source:HGNC Symbol;Acc:HGNC:30948] 0.0309769
ENSG00000129538 0.6741494 W0UV93 RNASE1 ribonuclease A family member 1, pancreatic [Source:HGNC Symbol;Acc:HGNC:10044] 0.0311997
ENSG00000168792 0.3032697 Q6UXT9 ABHD15 abhydrolase domain containing 15 [Source:HGNC Symbol;Acc:HGNC:26971] 0.0312953
ENSG00000139364 0.9882521 Q14DG7 TMEM132B transmembrane protein 132B [Source:HGNC Symbol;Acc:HGNC:29397] 0.0314522
ENSG00000171865 0.2558714 F8WD93 RNASEH1 ribonuclease H1 [Source:HGNC Symbol;Acc:HGNC:18466] 0.0315447
ENSG00000250328 1.0781965 MGC32805 uncharacterized LOC153163 [Source:NCBI gene (formerly Entrezgene);Acc:153163] 0.0315881
ENSG00000113282 0.1407376 Q14677 CLINT1 clathrin interactor 1 [Source:HGNC Symbol;Acc:HGNC:23186] 0.0316603
ENSG00000081985 1.8232459 A0A8Q3SIS8 IL12RB2 interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972] 0.0318911
ENSG00000162735 0.2088443 E9PS71 PEX19 peroxisomal biogenesis factor 19 [Source:HGNC Symbol;Acc:HGNC:9713] 0.0319414
ENSG00000167632 0.2355716 Q96Q05 TRAPPC9 trafficking protein particle complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:30832] 0.0320199
ENSG00000013561 0.1952730 E7EP22 RNF14 ring finger protein 14 [Source:HGNC Symbol;Acc:HGNC:10058] 0.0323624
ENSG00000115468 1.4868974 Q9BUP0 EFHD1 EF-hand domain family member D1 [Source:HGNC Symbol;Acc:HGNC:29556] 0.0323745
ENSG00000198690 0.2623711 A0A590UJ38 FAN1 FANCD2 and FANCI associated nuclease 1 [Source:HGNC Symbol;Acc:HGNC:29170] 0.0325689
ENSG00000140323 1.1656796 A7MBM2 DISP2 dispatched RND transporter family member 2 [Source:HGNC Symbol;Acc:HGNC:19712] 0.0327084
ENSG00000100865 0.3902211 Q9BW66 CINP cyclin dependent kinase 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:23789] 0.0328073
ENSG00000075336 0.3280401 A8K1K8 TIMM21 translocase of inner mitochondrial membrane 21 [Source:HGNC Symbol;Acc:HGNC:25010] 0.0328172
ENSG00000157450 0.1834695 H0YKK5 RNF111 ring finger protein 111 [Source:HGNC Symbol;Acc:HGNC:17384] 0.0328653
ENSG00000060339 0.1916609 A0A0C4DGG8 CCAR1 cell division cycle and apoptosis regulator 1 [Source:HGNC Symbol;Acc:HGNC:24236] 0.0328789
ENSG00000176595 0.6607479 O94819 KBTBD11 kelch repeat and BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29104] 0.0332368
ENSG00000178502 0.2895669 Q9NVR0 KLHL11 kelch like family member 11 [Source:HGNC Symbol;Acc:HGNC:19008] 0.0337433
ENSG00000129696 0.3583897 Q6NXR4 TTI2 TELO2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:26262] 0.0339946
ENSG00000187531 0.3572931 Q9NRC8 SIRT7 sirtuin 7 [Source:HGNC Symbol;Acc:HGNC:14935] 0.0340036
ENSG00000117602 0.1419267 Q9UKA8 RCAN3 RCAN family member 3 [Source:HGNC Symbol;Acc:HGNC:3042] 0.0340075
ENSG00000077514 0.2493646 A0A024R5M8 POLD3 DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932] 0.0340088
ENSG00000151692 1.1476514 P50876 RNF144A ring finger protein 144A [Source:HGNC Symbol;Acc:HGNC:20457] 0.0341528
ENSG00000070269 0.2723476 G3V4A2 TMEM260 transmembrane protein 260 [Source:HGNC Symbol;Acc:HGNC:20185] 0.0342099
ENSG00000125952 0.1825386 P61244 MAX MYC associated factor X [Source:HGNC Symbol;Acc:HGNC:6913] 0.0345283
ENSG00000099330 0.4162866 M0QZ36 OCEL1 occludin/ELL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26221] 0.0351007
ENSG00000164023 0.1723936 A0A024RDH4 SGMS2 sphingomyelin synthase 2 [Source:HGNC Symbol;Acc:HGNC:28395] 0.0355651
ENSG00000074603 0.1860203 H0YN53 DPP8 dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490] 0.0358399
ENSG00000099940 0.2087615 O95721 SNAP29 synaptosome associated protein 29 [Source:HGNC Symbol;Acc:HGNC:11133] 0.0359003
ENSG00000270571 0.7396350 novel transcript, antisense to TACR1 0.0359253
ENSG00000126243 0.4114353 Q9BTN0 LRFN3 leucine rich repeat and fibronectin type III domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28370] 0.0361684
ENSG00000168067 0.5157736 F2Z2B3 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6864] 0.0362318
ENSG00000129968 0.2706558 Q96GS6 ABHD17A abhydrolase domain containing 17A, depalmitoylase [Source:HGNC Symbol;Acc:HGNC:28756] 0.0366697
ENSG00000066044 0.1750944 Q15717 ELAVL1 ELAV like RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:3312] 0.0367779
ENSG00000134243 0.1515988 A0A0J9YX61 SORT1 sortilin 1 [Source:HGNC Symbol;Acc:HGNC:11186] 0.0370162
ENSG00000049656 0.2074948 Q96KA5 CLPTM1L CLPTM1 like [Source:HGNC Symbol;Acc:HGNC:24308] 0.0370162
ENSG00000163382 0.2488481 A0A7P0TA18 NAXE NAD(P)HX epimerase [Source:HGNC Symbol;Acc:HGNC:18453] 0.0372229
ENSG00000112996 0.1895755 Q9NP92 MRPS30 mitochondrial ribosomal protein S30 [Source:HGNC Symbol;Acc:HGNC:8769] 0.0374631
ENSG00000189308 0.2815410 Q6MZP7 LIN54 lin-54 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:25397] 0.0375965
ENSG00000141858 0.2434746 E9PIW9 SAMD1 sterile alpha motif domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17958] 0.0378006
ENSG00000168818 0.2216402 Q9P2W9 STX18 syntaxin 18 [Source:HGNC Symbol;Acc:HGNC:15942] 0.0380203
ENSG00000096080 0.3236326 Q9NVS2 MRPS18A mitochondrial ribosomal protein S18A [Source:HGNC Symbol;Acc:HGNC:14515] 0.0381649
ENSG00000138802 0.1749577 O95487 SEC24B SEC24 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10704] 0.0383301
ENSG00000198720 0.7718773 Q86YJ7 ANKRD13B ankyrin repeat domain 13B [Source:HGNC Symbol;Acc:HGNC:26363] 0.0385166
ENSG00000287642 1.1546612 novel transcript, antisense to FHDC1 0.0393861
ENSG00000171862 0.1434744 A0A8V8TP77 PTEN phosphatase and tensin homolog [Source:HGNC Symbol;Acc:HGNC:9588] 0.0394345
ENSG00000243477 1.0060763 C9J451 NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit [Source:HGNC Symbol;Acc:HGNC:30252] 0.0396920
ENSG00000164329 0.1918805 D6RAF2 TENT2 terminal nucleotidyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:26776] 0.0397049
ENSG00000270362 0.4013924 HMGN3-AS1 HMGN3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48984] 0.0397438
ENSG00000155729 0.2962867 Q6PI47 KCTD18 potassium channel tetramerization domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26446] 0.0398834
ENSG00000272841 0.7469836 MAP3K4-AS1 MAP3K4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:55048] 0.0398834
ENSG00000166394 0.2982983 E9PRM4 CYB5R2 cytochrome b5 reductase 2 [Source:HGNC Symbol;Acc:HGNC:24376] 0.0398834
ENSG00000134453 0.2453034 Q96I25 RBM17 RNA binding motif protein 17 [Source:HGNC Symbol;Acc:HGNC:16944] 0.0400999
ENSG00000129009 1.4574058 H0YL90 ISLR immunoglobulin superfamily containing leucine rich repeat [Source:HGNC Symbol;Acc:HGNC:6133] 0.0401095
ENSG00000090382 0.4663886 P61626 LYZ lysozyme [Source:HGNC Symbol;Acc:HGNC:6740] 0.0403034
ENSG00000215196 0.9850964 BASP1-AS1 BASP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26609] 0.0405882
ENSG00000137106 0.2812191 U3KQ56 GRHPR glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570] 0.0407011
ENSG00000205593 0.2143518 Q8NEG7 DENND6B DENN domain containing 6B [Source:HGNC Symbol;Acc:HGNC:32690] 0.0413244
ENSG00000286811 1.8104343 novel transcript 0.0417857
ENSG00000197858 0.2360978 E9PQ31 GPAA1 glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446] 0.0422497
ENSG00000197345 0.3083255 Q7Z2W9 MRPL21 mitochondrial ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:14479] 0.0426523
ENSG00000100422 0.2780193 Q8TCT0 CERK ceramide kinase [Source:HGNC Symbol;Acc:HGNC:19256] 0.0427101
ENSG00000105877 0.2217329 Q96DT5 DNAH11 dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942] 0.0427606
ENSG00000120729 1.6620292 B4DT68 MYOT myotilin [Source:HGNC Symbol;Acc:HGNC:12399] 0.0428383
ENSG00000204560 0.2253864 Q5SQH4 DHX16 DEAH-box helicase 16 [Source:HGNC Symbol;Acc:HGNC:2739] 0.0428925
ENSG00000183734 1.1563363 Q99929 ASCL2 achaete-scute family bHLH transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:739] 0.0429975
ENSG00000100263 0.4747990 B0QYJ2 RHBDD3 rhomboid domain containing 3 [Source:HGNC Symbol;Acc:HGNC:1308] 0.0430531
ENSG00000140990 0.2441873 A8K761 NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 [Source:HGNC Symbol;Acc:HGNC:7696] 0.0431533
ENSG00000137944 0.2346448 Q6YP21 KYAT3 kynurenine aminotransferase 3 [Source:HGNC Symbol;Acc:HGNC:33238] 0.0434897
ENSG00000177707 0.2571100 Q9NQS3 NECTIN3 nectin cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17664] 0.0435166
ENSG00000168297 0.3113391 W5RWE6 PXK PX domain containing serine/threonine kinase like [Source:HGNC Symbol;Acc:HGNC:23326] 0.0438715
ENSG00000170248 0.1289501 A0A3B3IT07 PDCD6IP programmed cell death 6 interacting protein [Source:HGNC Symbol;Acc:HGNC:8766] 0.0439706
ENSG00000164638 1.3547340 C9IYM7 SLC29A4 solute carrier family 29 member 4 [Source:HGNC Symbol;Acc:HGNC:23097] 0.0440845
ENSG00000077312 0.3001007 P09012 SNRPA small nuclear ribonucleoprotein polypeptide A [Source:HGNC Symbol;Acc:HGNC:11151] 0.0442471
ENSG00000125355 1.0765329 Q5JRV8 TMEM255A transmembrane protein 255A [Source:HGNC Symbol;Acc:HGNC:26086] 0.0450200
ENSG00000115758 0.2309054 A0A8V8TQA2 ODC1 ornithine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:8109] 0.0451570
ENSG00000110987 0.2473990 Q4VC05 BCL7A BAF chromatin remodeling complex subunit BCL7A [Source:HGNC Symbol;Acc:HGNC:1004] 0.0453919
ENSG00000018510 0.2032177 B7Z3Q4 AGPS alkylglycerone phosphate synthase [Source:HGNC Symbol;Acc:HGNC:327] 0.0459486
ENSG00000090674 0.4452105 M0QXD0 MCOLN1 mucolipin TRP cation channel 1 [Source:HGNC Symbol;Acc:HGNC:13356] 0.0460285
ENSG00000196642 0.1754157 Q3YEC7 RABL6 RAB, member RAS oncogene family like 6 [Source:HGNC Symbol;Acc:HGNC:24703] 0.0460809
ENSG00000060140 0.2861393 F5H4G3 STYK1 serine/threonine/tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18889] 0.0462158
ENSG00000106541 0.2094785 O95994 AGR2 anterior gradient 2, protein disulphide isomerase family member [Source:HGNC Symbol;Acc:HGNC:328] 0.0462509
ENSG00000132017 0.2765335 K7ENG0 DCAF15 DDB1 and CUL4 associated factor 15 [Source:HGNC Symbol;Acc:HGNC:25095] 0.0465601
ENSG00000111640 0.2121595 V9HVZ4 GAPDH glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141] 0.0467956
ENSG00000204060 0.8811968 A0A8I5QKU9 FOXO6 forkhead box O6 [Source:HGNC Symbol;Acc:HGNC:24814] 0.0472523
ENSG00000101310 0.1750800 Q15437 SEC23B SEC23 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10702] 0.0474201
ENSG00000028528 0.1935703 H0YK58 SNX1 sorting nexin 1 [Source:HGNC Symbol;Acc:HGNC:11172] 0.0476788
ENSG00000126215 0.5031970 G3V3H9 XRCC3 X-ray repair cross complementing 3 [Source:HGNC Symbol;Acc:HGNC:12830] 0.0477485
ENSG00000183864 0.1695140 Q14106 TOB2 transducer of ERBB2, 2 [Source:HGNC Symbol;Acc:HGNC:11980] 0.0479177
ENSG00000135365 0.2011899 E9PLU5 PHF21A PHD finger protein 21A [Source:HGNC Symbol;Acc:HGNC:24156] 0.0490093
ENSG00000220205 0.2838273 J3QRU4 VAMP2 vesicle associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:12643] 0.0490937
ENSG00000204385 0.1399954 Q53GD3 SLC44A4 solute carrier family 44 member 4 [Source:HGNC Symbol;Acc:HGNC:13941] 0.0496938

There are 377 candidate genes for the suppression of SPREADS through pitavastatin treatment.

Highlight on volcano plot

Heatmap

Subselect genes per consistency in replicates?

Enrichment analysis (Over-representation analysis)

GOBP

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
REACTOME_CHOLESTEROL_BIOSYNTHESIS 24 0.9100095 2.415338 0.0000000 0.0000000 0.0000000 887 CYP51A1/MVD/ACAT2/HMGCS1/EBP/FDPS/LSS/DHCR7/MSMO1/HMGCR/HSD17B7/IDI1/FDFT1/SQLE/NSDHL/SC5D/TM7SF2/MVK
REACTOME_CELL_CYCLE_CHECKPOINTS 281 -0.4899724 -2.015469 0.0000000 0.0000000 0.0000000 2032 CENPH/CENPS/CCNA2/CENPU/CHEK1/DNA2/B9D2/CENPM/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/CDC7/MCM8/KIF18A/PKMYT1/ABRAXAS1/CDC25A/BLM/BRIP1/SPC24/H2BC7/H2BC3/ANAPC4/CCNB1/ORC1/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/EXO1/SGO2/H2BC14/NDC80/H2BC10/MAD2L1/CENPF/CCNB2/H2BC17/CENPE/NUF2/CCNE2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/MCM10/ERCC6L/CDC20/GTSE1/CDC25C/UBE2C/BUB1B/SPC25
REACTOME_M_PHASE 390 -0.4453607 -1.894092 0.0000000 0.0000000 0.0000000 2064 SMC2/CENPH/H3C11/CENPS/CETN2/H3C1/CENPU/VRK1/B9D2/ESPL1/CENPM/H2BC11/H3C13/CEP78/H2BC15/CEP70/H4C4/H4C1/H2AC4/KIF18A/H3C10/SPC24/H2BC7/FBXO5/H2BC3/ANAPC4/CCNB1/H4C13/CENPK/H4C9/PTTG1/CENPP/PRKAR2B/H2BC13/KNL1/H2AC14/SGO2/CDCA5/H2BC14/NDC80/H2BC10/LMNB1/MAD2L1/CENPF/H3C7/CCNB2/NCAPH/H2BC17/H3C12/CENPE/NEK2/NUF2/PLK1/PLK4/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/KIF20A/CDC20/H3C3/NCAPG/UBE2C/H3C8/BUB1B/SPC25/H3C2
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP 42 0.7926678 2.421620 0.0000000 0.0000003 0.0000002 887 CYP51A1/MVD/HMGCS1/FDPS/ELOVL6/LSS/DHCR7/HMGCR/IDI1/HELZ2/FDFT1/SQLE/SCD/SC5D/FASN/TM7SF2/MVK
REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES 61 -0.6985479 -2.328780 0.0000000 0.0000003 0.0000002 3700 H2AX/H3C6/H2BC6/NCAPD3/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SMC4/H2BC9/SMC2/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/PLK1/CDK1/H3C3/H3C8/H3C2
REACTOME_MITOTIC_SPINDLE_CHECKPOINT 108 -0.6067154 -2.222323 0.0000000 0.0000004 0.0000003 1009 CENPH/CENPS/CENPU/B9D2/CENPM/KIF18A/SPC24/ANAPC4/CENPK/CENPP/KNL1/SGO2/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_DNA_REPLICATION 176 -0.5163359 -2.046794 0.0000000 0.0000010 0.0000009 2017 H3C11/H3C1/CCNA2/DNA2/H2BC11/H3C13/RPA3/POLE2/H2BC15/LIG1/H4C4/H4C1/CDC7/H2AC4/MCM8/GINS1/GINS2/POLA2/H3C10/H2BC7/H2BC3/ANAPC4/ORC1/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/CDT1/GMNN/H2BC14/H2BC10/H3C7/H2BC17/H3C12/CCNE2/MCM10/H3C3/UBE2C/H3C8/H3C2
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 63 -0.6768095 -2.275381 0.0000000 0.0000011 0.0000009 3971 NPM1/H2BC12/RBBP4/ITGB3BP/RUVBL1/RBBP7/CENPC/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MIS18A/H2BC9/MIS18BP1/CENPH/CENPS/CENPU/CENPM/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/H2AC14/H2BC14/H2BC10/CENPW/H2BC17/OIP5/HJURP
REACTOME_HDACS_DEACETYLATE_HISTONES 81 -0.6372707 -2.229347 0.0000000 0.0000011 0.0000009 2162 H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA 61 -0.6767456 -2.256096 0.0000000 0.0000014 0.0000011 3961 H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/PHF19/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES 66 -0.6627525 -2.232308 0.0000000 0.0000014 0.0000011 3831 RBBP7/ACTL6A/H2AX/H3C6/H4C5/SMARCA2/SMARCE1/H4C12/WDR77/H2AJ/H4C6/H2AZ2/H4C3/H4C2/H2AC15/H3C11/H3C1/H3C13/H4C4/H4C1/H2AC4/H3C10/H2AC16/SMARCD3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2AC14/H2AC12/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_MEIOSIS 95 -0.6002354 -2.158029 0.0000000 0.0000014 0.0000011 3813 H3-3A/SYCP2/H2AX/H3C6/H2BC6/H4C5/ATM/BRCA2/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SYNE1/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/DMC1/H3C3/H3C8/H3C2
REACTOME_CHROMOSOME_MAINTENANCE 126 -0.5583225 -2.075482 0.0000000 0.0000014 0.0000011 4152 H2BC8/PRIM1/POLA1/RPA1/NPM1/POLR2I/H2BC12/RBBP4/ITGB3BP/RUVBL1/RBBP7/H3-3A/CENPC/H2AX/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/POLD1/RFC3/WRAP53/H2AJ/WRN/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/MIS18A/H2BC9/CHTF8/MIS18BP1/CENPH/CENPS/CCNA2/CENPU/DNA2/CENPM/H2BC11/RPA3/H2BC15/LIG1/H4C4/H4C1/H2AC4/BLM/POLA2/H2BC7/H2BC3/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/H2AC14/DSCC1/H2BC14/H2BC10/CENPW/H2BC17/OIP5/HJURP
REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION 64 -0.6735249 -2.256106 0.0000000 0.0000014 0.0000011 3961 H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION 56 -0.6751004 -2.208585 0.0000000 0.0000016 0.0000013 4003 SUV39H1/H2BC12/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF 55 0.7512270 2.404642 0.0000000 0.0000016 0.0000013 887 CYP51A1/MVD/HMGCS1/FDPS/ELOVL6/LSS/DHCR7/HMGCR/INSIG1/IDI1/HELZ2/FDFT1/SQLE/SCD/SC5D/FASN/TM7SF2/MVK
REACTOME_MEIOTIC_RECOMBINATION 70 -0.6618302 -2.258802 0.0000000 0.0000016 0.0000013 3700 H2AX/H3C6/H2BC6/H4C5/ATM/BRCA2/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/DMC1/H3C3/H3C8/H3C2
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 54 0.7385567 2.350001 0.0000000 0.0000017 0.0000014 1781 SOCS1/IFIT2/MX2/RSAD2/ISG15/OAS3/ISG20/OASL/IFIT3/OAS1/MX1/IFIT1/IFI35/IFITM1/USP18/IFI6/EGR1/IRF7/BST2/IFI27/XAF1/OAS2/IFITM3/SOCS3/IFIT5/IRF6/ADAR/STAT1
REACTOME_HATS_ACETYLATE_HISTONES 128 -0.5551664 -2.075388 0.0000000 0.0000017 0.0000014 4152 H2BC8/H2BC18/MSL3/MCRS1/MORF4L1/H2BC12/KAT2A/EP400/RUVBL1/RBBP7/ACTL6A/ELP6/H3C6/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/HAT1/H4C6/H2BC4/ING4/H4C3/H4C2/JADE1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 26 -0.8200483 -2.306116 0.0000000 0.0000019 0.0000016 871 ANAPC4/MAD2L1/NEK2/CDC20/UBE2C/BUB1B
REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3 53 -0.6949488 -2.285318 0.0000000 0.0000019 0.0000016 3700 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/AR/H3C3/H3C8/H3C2
REACTOME_RHO_GTPASE_EFFECTORS 290 -0.4445913 -1.840399 0.0000000 0.0000020 0.0000016 1023 H3C10/SPC24/H2BC7/MYLK/S100A9/H2BC3/CYBB/H4C13/CENPK/H4C9/WAS/S100A8/DIAPH3/CENPP/H2BC13/KNL1/H2AC14/SGO2/CIT/NOX1/H2BC14/NDC80/KIF14/H2BC10/MAD2L1/CENPF/H3C7/H2BC17/H3C12/CENPE/NUF2/PLK1/SGO1/IQGAP3/SKA1/BIRC5/AR/KIF2C/BUB1/ERCC6L/CDC20/H3C3/CDC25C/H3C8/BUB1B/SPC25/H3C2
REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION 57 -0.6786559 -2.227959 0.0000000 0.0000024 0.0000020 3700 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ORC1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_DNA_METHYLATION 52 -0.6918105 -2.263368 0.0000001 0.0000030 0.0000024 3813 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION 98 -0.5865076 -2.124470 0.0000001 0.0000031 0.0000026 3961 H2BC12/POLR1C/KAT2A/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE 78 -0.6253839 -2.173370 0.0000001 0.0000032 0.0000026 3961 H2BC12/POLR1C/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX 78 -0.6238631 -2.168085 0.0000001 0.0000036 0.0000030 3852 RUVBL1/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/PYGO1/H2AJ/TCF4/H4C6/H2BC4/H2AZ2/BCL9/H4C3/H4C2/H2BC9/RUNX3/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/AXIN2/H2BC13/H2AC14/TCF7/LEF1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS 95 -0.5820628 -2.092693 0.0000001 0.0000047 0.0000039 3967 POLR2I/H2BC12/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/NUP37/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/NDC1/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS 21 -0.8388424 -2.252758 0.0000002 0.0000067 0.0000055 871 ANAPC4/MAD2L1/CDC20/UBE2C/BUB1B
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION 115 -0.5579830 -2.062884 0.0000002 0.0000095 0.0000079 1009 SPC24/CCNB1/CENPK/CENPP/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CCNB2/CENPE/NUF2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/BUB1B/SPC25
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 97 -0.5690216 -2.050953 0.0000003 0.0000107 0.0000089 2866 H4C6/H2BC4/NOTCH1/MAML3/H2AZ2/H4C3/H4C2/H2BC9/NOTCH3/H3C11/TFDP2/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/ATP2A3/H2BC13/H2AC14/E2F1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/ST3GAL6/MIR449C/H3C3/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS 74 -0.6270305 -2.152107 0.0000003 0.0000109 0.0000090 3700 H2AX/RXRA/H3C6/H2BC6/H4C5/DEK/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/TFDP2/H3C1/CEBPA/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/E2F1/FLI1/LEF1/H2BC14/GATA2/H2BC10/H3C7/MYB/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 96 -0.5724421 -2.062934 0.0000003 0.0000113 0.0000093 4003 SUV39H1/H2BC12/POLR1C/SUDS3/H3-3A/H2AX/H3C6/H2BC6/H4C5/GTF2H5/H2BC5/H4C12/TTF1/H2AJ/SAP30/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_REPRODUCTION 108 -0.5543982 -2.030692 0.0000004 0.0000129 0.0000106 2521 H4C3/H4C2/SYNE1/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/OVGP1/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/CATSPERD/DMC1/H3C3/H3C8/H3C2
REACTOME_HCMV_LATE_EVENTS 103 -0.5576692 -2.037416 0.0000004 0.0000130 0.0000107 2521 H4C3/H4C2/NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE 223 -0.4551216 -1.839857 0.0000004 0.0000133 0.0000110 1009 SPC24/FBXO5/ANAPC4/CCNB1/CENPK/PTTG1/CENPP/KNL1/SGO2/CDCA5/NDC80/LMNB1/MAD2L1/CENPF/CCNB2/CENPE/NUF2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH 89 -0.5836347 -2.066148 0.0000004 0.0000138 0.0000114 4152 H2BC8/PRIM1/POLA1/FOXO3/H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/CDK5/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/CDC25A/POLA2/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/CAPNS2/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/H3C3/CDC25C/H3C8/H3C2
REACTOME_MITOTIC_PROMETAPHASE 191 -0.4729286 -1.881723 0.0000005 0.0000151 0.0000124 1009 PCM1/PDS5B/CEP76/CCP110/SMC4/NME7/SMC2/CENPH/CENPS/CETN2/CENPU/B9D2/CENPM/CEP78/CEP70/KIF18A/SPC24/CCNB1/CENPK/CENPP/PRKAR2B/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CCNB2/NCAPH/CENPE/NEK2/NUF2/PLK1/PLK4/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/NCAPG/BUB1B/SPC25
REACTOME_MITOTIC_PROPHASE 130 -0.5153263 -1.934169 0.0000006 0.0000164 0.0000135 2643 H2AZ2/PRKCB/H4C3/H4C2/SMC4/NDC1/H2BC9/SMC2/H3C11/H3C1/VRK1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/CCNB2/H2BC17/H3C12/PLK1/CDK1/H3C3/H3C8/H3C2
REACTOME_DNA_REPLICATION_PRE_INITIATION 133 -0.5226252 -1.969144 0.0000007 0.0000205 0.0000169 1665 H2BC11/H3C13/RPA3/POLE2/H2BC15/H4C4/H4C1/CDC7/H2AC4/MCM8/POLA2/H3C10/H2BC7/H2BC3/ORC1/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/CDT1/GMNN/H2BC14/H2BC10/H3C7/H2BC17/H3C12/MCM10/H3C3/H3C8/H3C2
REACTOME_INTERFERON_SIGNALING 170 0.5154131 1.942624 0.0000007 0.0000205 0.0000169 2535 SOCS1/IFIT2/MX2/RSAD2/ISG15/CD44/OAS3/ISG20/OASL/GBP5/IFIT3/OAS1/MX1/IFIT1/IFI35/IFITM1/USP18/IFI6/EGR1/IRF7/BST2/IFI27/XAF1/OAS2/PML/IFITM3/ICAM1/SOCS3/PTAFR/IFIT5/UBE2L6/TRIM14/IRF6/HERC5/ADAR/STAT1/TRIM21/EIF2AK2/TRIM25/NUP188/EIF4E3/TRIM45/SEC13/HLA-DQB2/GBP1/HLA-F/HLA-C/STAT2/NEDD4/EIF4G1/TRIM5/PTPN11/GBP4
REACTOME_PHOSPHORYLATION_OF_THE_APC_C 20 -0.8158156 -2.160935 0.0000010 0.0000284 0.0000234 871 ANAPC4/CCNB1/PLK1/CDK1/UBE2C
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS 178 -0.4707924 -1.862121 0.0000013 0.0000339 0.0000279 1009 SPC24/ANAPC4/CENPK/PTTG1/CENPP/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B 24 -0.7811961 -2.161560 0.0000016 0.0000412 0.0000340 871 ANAPC4/CCNB1/CDK1/CDC20/UBE2C
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION 79 -0.5910492 -2.059283 0.0000016 0.0000412 0.0000340 3961 H2BC12/POLR1C/KAT2A/H3-3A/H2AX/H3C6/H2BC6/H4C5/DEK/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 94 -0.5712527 -2.057096 0.0000016 0.0000412 0.0000340 3961 H2BC12/POLR1C/KAT2A/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/DEK/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_BASE_EXCISION_REPAIR 81 -0.5794047 -2.026916 0.0000024 0.0000582 0.0000480 4574 H2AC8/H4C8/LIG3/H2AC6/XRCC1/APEX1/NEIL1/H2BC8/NEIL2/RPA1/H2BC12/UNG/H2AX/NTHL1/H2BC6/H4C5/H2BC5/H4C12/POLD1/RFC3/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/H2BC9/H2BC11/RPA3/POLE2/H2BC15/LIG1/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT 89 -0.5621227 -1.989993 0.0000024 0.0000591 0.0000487 4260 RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/H2AX/H2BC6/H4C5/RAD9B/ATM/H2BC5/H4C12/RFC3/CHEK2/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/H2BC9/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/H2BC17/CDK1/CDC25C
REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION 134 -0.5008421 -1.889252 0.0000036 0.0000846 0.0000697 4003 SUV39H1/H2BC12/POLR1C/KAT2A/RBBP4/SUDS3/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/DEK/H2BC5/H4C12/TTF1/H2AJ/SAP30/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/TET1/H4C4/H4C1/H2AC4/PHF19/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS 16 -0.8401569 -2.091342 0.0000043 0.0000987 0.0000813 1178 PKMYT1/CDC25A/CCNB1/FOXM1/CENPF/CCNB2/PLK1/CDC25C/MYBL2
REACTOME_SIGNALING_BY_INTERLEUKINS 375 0.4114043 1.674962 0.0000047 0.0001064 0.0000877 2711 NOS2/CISH/IL19/SOCS1/IL1R2/IL13RA2/ALOX15/SERPINB2/MMP1/IL1RL1/CXCL10/CCL4/MAOA/IL32/IL12RB2/IL36G/NOD2/IL17C/CXCL8/CCL22/CD36/IL2RG/IL31RA/EBI3/FOS/MAPKAPK3/BCL2/IL36A/VEGFA/SOCS2/IL1A/FGF2/CLCF1/GATA3/CD86/NFKB2/IL1RN/ANXA1/HCK/OSMR/IFNLR1/STX1A/IL18R1/IRAK2/NFKBIA/STX3/HIF1A/PTGS2/CXCL1/IL23A/MYD88/ICAM1/TNF/LIFR/PSMA6/GAB2/SOCS3/DUSP3/IRS2/HMOX1/LIF/IL4R/DUSP7/PTAFR/MAPK11/CCL5/LGALS9/FYN/SOX2/CXCL2/ITGAM/PIM1/DUSP6/IL15RA/IL1RL2/STAT1/IRAK1/RIPK2/IL20RB/MUC1/TEC/PTPN9/JUNB/MAP3K8/IL15/PSMC4/TIMP1/BATF/NFKBIB/SQSTM1/CDKN1A/AKT1/JUN/MSN/RORA/MYC/INPPL1/IRAK4/STAT2/MAPKAPK2/RELA/STX4/PTPN11/CCL20/IL27RA/NOD1/CSF2/PAK2/IL6ST/STXBP2/PSMD11/PTPN12/MAP2K1/ALOX5/RALA/CFL1/SYK
REACTOME_GENE_SILENCING_BY_RNA 123 -0.5110819 -1.898076 0.0000056 0.0001240 0.0001022 3700 H2AX/HSP90AA1/H3C6/TDRD1/H2BC6/H4C5/H2BC5/H4C12/NUP37/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/HENMT1/NDC1/H2BC9/H3C11/H3C1/TDRD6/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/MIR23B/H3C10/H2BC7/H2BC3/PIWIL2/H4C13/H4C9/H2BC13/H2AC14/MYBL1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES 446 0.3896559 1.613445 0.0000057 0.0001241 0.0001023 2992 NTRK1/SOCS1/ARC/CD274/NCF1/PTPRO/TRIB3/PCSK6/COL6A1/HBEGF/SGK1/BDNF/PRDM1/ATP6V1C2/KL/FGFR4/ATP6V0D2/FGFBP1/NTRK2/FLT1/IL2RG/EREG/NTRK3/FOS/F3/MAPKAPK3/VEGFA/TNS4/FOSB/DOCK3/FGF2/EGR1/APOE/EGR2/ITPR3/MET/GRB10/KITLG/ANOS1/TRIB1/NRP2/HIF1A/MKNK1/FOSL1/MAPK12/KDR/ATP6V0A2/LAMA4/GAB2/DUSP3/IRS2/ASCL1/YAP1/ID3/AP2B1/SPHK1/KLB/DUSP7/SPRED2/MAPK11/THBS1/KRAS/BCAR1/FYN/DUSP6/AXL/SH2B3/MST1R/JUND/NCF2/ADAP1/ITGAV/AP2M1/LAMB3/SPINT2/STAT1/RAC1/RAB4B/AKT3/TGFA/TEC/JUNB/ATP6V1E2/ACTB/GTF2F2/NRAS/FURIN/PTK6/SPP1/AKT1/LAMB1/ADAM17/MYC/NEDD4/DIAPH1/MAPKAPK2/SHC2/ITGA3/SH3GL1/COL5A2/SRC/PRR5/PTPN11/EPS15/PAK2/PTPN12/MAPK13/MAP2K1/EPS15L1/RALA/ITPR2/ACTG1/TIAM1/FGFBP3/GGA3/LAMA3/VAV2/LAMB2/RAP1A/NCF4/DOCK7/CSK/CAV1/IGF2/ESRP2/AP2A2/PTPN3/ELMO2/SPINT1/CRK/CBL
REACTOME_SIGNALING_BY_NTRKS 123 0.5508215 1.989794 0.0000074 0.0001584 0.0001306 2974 NTRK1/ARC/PTPRO/PCSK6/SGK1/BDNF/NTRK2/NTRK3/FOS/F3/MAPKAPK3/FOSB/DOCK3/EGR1/EGR2/TRIB1/FOSL1/MAPK12/DUSP3/IRS2/ASCL1/ID3/AP2B1/DUSP7/MAPK11/KRAS/FYN/DUSP6/JUND/AP2M1/RAC1/JUNB/NRAS/FURIN/MAPKAPK2/SHC2/SRC/PTPN11/MAPK13/MAP2K1/RALA/TIAM1/RAP1A/AP2A2/CRK
REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS 104 -0.5287602 -1.933478 0.0000084 0.0001753 0.0001445 3967 POLR2I/H2BC12/RBBP4/RBBP7/H3-3A/H2AX/RXRA/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/HOXA1/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/HOXB4/PBX1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP 99 -0.5262306 -1.912968 0.0000085 0.0001753 0.0001445 2162 H2BC9/CDKN2C/H3C11/H3C1/CCNA2/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ANAPC4/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/UBE2C/H3C8/H3C2
REACTOME_RHO_GTPASES_ACTIVATE_PKNS 78 -0.5646956 -1.962463 0.0000099 0.0002024 0.0001668 2162 H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/AR/H3C3/CDC25C/H3C8/H3C2
REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE 46 -0.6384464 -2.023870 0.0000105 0.0002103 0.0001734 3700 H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_HOMOLOGY_DIRECTED_REPAIR 130 -0.4820605 -1.809312 0.0000139 0.0002732 0.0002252 4572 H4C8/RAD50/ATR/LIG3/XRCC1/RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/ERCC4/H2AX/EME1/H2BC6/TIMELESS/H4C5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/WRN/RAD52/H4C6/RAD51B/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CCNA2/CHEK1/DNA2/H2BC11/RPA3/POLE2/H2BC15/BRCA1/H4C4/XRCC2/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/POLQ/H4C13/H4C9/RAD51AP1/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_RHO_GTPASES_ACTIVATE_FORMINS 129 -0.4800147 -1.793853 0.0000144 0.0002780 0.0002291 735 CENPK/DIAPH3/CENPP/KNL1/SGO2/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/BUB1B/SPC25
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS 112 -0.5019533 -1.847652 0.0000159 0.0003033 0.0002499 1665 H2BC9/H3C11/H3C1/H2BC11/H3C13/LMO2/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/GATA2/H2BC10/H3C7/MYB/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_BASE_EXCISION_REPAIR_AP_SITE_FORMATION 53 -0.6185152 -2.033968 0.0000177 0.0003313 0.0002731 4574 H2AC8/H4C8/H2AC6/NEIL1/H2BC8/NEIL2/H2BC12/UNG/H2AX/NTHL1/H2BC6/H4C5/H2BC5/H4C12/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_TELOMERE_MAINTENANCE 100 -0.5141976 -1.871398 0.0000195 0.0003590 0.0002959 4152 H2BC8/PRIM1/POLA1/RPA1/POLR2I/H2BC12/RUVBL1/H3-3A/H2AX/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/POLD1/RFC3/WRAP53/H2AJ/WRN/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/H2BC9/CHTF8/CCNA2/DNA2/H2BC11/RPA3/H2BC15/LIG1/H4C4/H4C1/H2AC4/BLM/POLA2/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/DSCC1/H2BC14/H2BC10/H2BC17
REACTOME_AMYLOID_FIBER_FORMATION 85 -0.5397976 -1.894173 0.0000227 0.0004123 0.0003398 2162 H2BC9/H3C11/H3C1/H2BC11/H3C13/CALB1/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/LTF/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE 20 -0.7733783 -2.048526 0.0000237 0.0004226 0.0003483 871 ANAPC4/CDC14A/CDC20/UBE2C
REACTOME_METABOLISM_OF_STEROIDS 126 0.5279357 1.918570 0.0000317 0.0005580 0.0004598 1035 CYP51A1/MVD/ACAT2/HMGCS1/EBP/FDPS/ELOVL6/LSS/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/SLCO1B1/STARD4/HELZ2/FDFT1/SQLE/SCD/NSDHL/SC5D/STARD5/FASN/SRD5A3/TM7SF2/CYP27B1/MVK/HSD17B12/SLCO1B3
REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING 89 0.5704236 1.983418 0.0000351 0.0006089 0.0005018 2342 NOS2/SOCS1/IL13RA2/ALOX15/MMP1/MAOA/CXCL8/CCL22/CD36/IL2RG/FOS/BCL2/VEGFA/IL1A/FGF2/GATA3/ANXA1/HIF1A/PTGS2/IL23A/ICAM1/TNF/SOCS3/HMOX1/LIF/IL4R/SOX2/ITGAM/PIM1/STAT1/MUC1/JUNB/TIMP1/BATF/CDKN1A/AKT1/RORA/MYC
REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS 85 -0.5342726 -1.874786 0.0000366 0.0006250 0.0005151 918 FBXO5/ANAPC4/CCNB1/PTTG1/CDC14A/MAD2L1/NEK2/PLK1/CDK1/CDC20/UBE2C/BUB1B
REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS 92 -0.5235500 -1.865411 0.0000494 0.0008315 0.0006852 4260 RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/H2AX/H2BC6/TIMELESS/H4C5/RAD9B/ATM/H2BC5/H4C12/RFC3/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/CCNA2/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_CELLULAR_SENESCENCE 181 -0.4193726 -1.668964 0.0000704 0.0011673 0.0009621 2162 H2BC9/CDKN2C/H3C11/TFDP2/H3C1/CCNA2/H2BC11/H3C13/MAP2K6/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ANAPC4/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/H1-5/H2BC14/H2BC10/LMNB1/H3C7/H1-1/H2BC17/H3C12/CCNE2/H3C3/UBE2C/H3C8/H3C2
REACTOME_MEIOTIC_SYNAPSIS 62 -0.5705567 -1.904949 0.0001058 0.0017307 0.0014264 4574 H2AC8/H4C8/ATR/H2AC6/H2BC8/STAG2/H2BC12/SYCP2/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SYNE1/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H2BC17
REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES 65 -0.5501950 -1.849551 0.0001132 0.0018250 0.0015041 3239 SUV39H1/RBBP4/RBBP7/H3C6/H4C5/H4C12/KMT5C/SMYD3/H4C6/EZH2/H4C3/H4C2/DPY30/SMYD2/H3C11/H3C1/H3C13/H4C4/H4C1/H3C10/H4C13/H4C9/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_HDMS_DEMETHYLATE_HISTONES 45 -0.6149784 -1.942451 0.0001160 0.0018445 0.0015202 2521 H4C3/H4C2/H3C11/H3C1/H3C13/H4C4/H4C1/H3C10/H4C13/H4C9/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_NOTCH 217 -0.3967567 -1.603549 0.0001349 0.0021169 0.0017447 2019 NOTCH3/H3C11/TFDP2/DLL1/H3C1/PBX1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/HEY1/H3C10/NBEA/H2BC7/H2BC3/H4C13/HEY2/H4C9/PLXND1/ATP2A3/NEURL1/H2BC13/H2AC14/E2F1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/ST3GAL6/MIR449C/HEYL/H3C3/DLGAP5/H3C8/H3C2
REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION 134 -0.4540423 -1.712717 0.0001427 0.0022086 0.0018202 2866 H4C6/ERBB4/H2BC4/ESR1/H2AZ2/TFF3/H4C3/H4C2/H2BC9/H3C11/H3C1/CXXC5/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/MYB/H2BC17/H3C12/NR5A2/H3C3/H3C8/H3C2
REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE 58 -0.5750387 -1.902840 0.0001538 0.0023491 0.0019361 3967 H2AC8/H4C8/H2AC6/H2BC8/POLR2I/H2BC12/H3-3A/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17
REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE 111 -0.4762203 -1.749237 0.0001636 0.0024346 0.0020065 3030 H2AJ/MAPK10/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/CDKN2C/H3C11/TFDP2/H3C1/H2BC11/H3C13/MAP2K6/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_G2_M_CHECKPOINTS 160 -0.4274524 -1.656697 0.0001622 0.0024346 0.0020065 3582 MCM2/H2BC6/H4C5/RAD9B/ATM/H2BC5/MCM7/H4C12/RFC3/CHEK2/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/CDC7/MCM8/PKMYT1/ABRAXAS1/CDC25A/BLM/BRIP1/H2BC7/H2BC3/CCNB1/ORC1/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/CCNB2/H2BC17/CDK1/MCM10/GTSE1/CDC25C
REACTOME_CHROMATIN_MODIFYING_ENZYMES 255 -0.3805885 -1.552443 0.0001719 0.0025262 0.0020820 4713 RPS2/ENY2/ARID4A/HDAC2/SETD6/NSD3/H2AC8/H4C8/KDM3B/KDM4D/H2AC6/CHD4/EED/PRMT7/H2BC8/H2BC18/MSL3/MCRS1/KDM3A/MORF4L1/SUV39H1/H2BC12/KAT2A/RBBP4/SUDS3/EP400/RUVBL1/RBBP7/ACTL6A/ELP6/H2AX/H3C6/H2BC6/H4C5/SMARCA2/SMARCE1/H2BC5/H4C12/RUVBL2/HAT1/KMT5C/WDR77/H2AJ/SMYD3/SAP30/H4C6/H2BC4/ING4/H2AZ2/EZH2/H4C3/H4C2/JADE1/DPY30/H2BC9/SMYD2/PADI1/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/PADI2/H4C1/H2AC4/H3C10/H2AC16/H2BC7/SMARCD3/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ 63 -0.5518790 -1.855374 0.0001890 0.0027423 0.0022601 3762 TDP1/XRCC4/XRCC5/H4C8/RAD50/H2BC8/H2BC12/TP53BP1/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/H4C6/H2BC4/BARD1/H4C3/H4C2/MRE11/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2BC14/H2BC10/H2BC17
REACTOME_HCMV_EARLY_EVENTS 117 -0.4641200 -1.724741 0.0002180 0.0031243 0.0025749 2260 NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION 24 -0.6913693 -1.913010 0.0002440 0.0034549 0.0028473 1178 CCNA2/PKMYT1/CDC25A/CCNB1/FOXM1/CCNB2/PLK1/CDK1/CDC25C
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION 90 -0.5004047 -1.787646 0.0002726 0.0038135 0.0031429 5794 RPLP0/RPL26L1/RPL17/RPS11/RPL19/RPS16/RPL12/RPL10/RPS28/RPS27A/RPS9/RPS10/RPL27/EEF2/RPL39/RPS19/RPS3/RPSA/RPL41/RPL9/RPL7A/RPL37A/RPS27/RPS2/RPS29/RPS24/EEF1A1/EEF1B2/RPS5/RPS8/RPS15A/RPL36A/RPS21/RPS20/RPL34/RPL13/RPL24/RPS13/RPS12/RPL23A/RPS7/RPS23/RPL27A/RPL3/RPL32/RPL30/RPL29/RPL21/RPL31/RPL14/RPL13A/RPS6/RPL6/RPS14/RPL11/RPL37/RPS25/RPL35A/RPL22/RPL7/RPS18/RPL23/RPL4/RPS4X/RPL10A/RPS4Y1/RPL39L/RPL26/RPL15/RPL5/RPS3A
REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION 81 -0.5133707 -1.795911 0.0002831 0.0039127 0.0032247 2866 H4C6/H2BC4/H2AZ2/H4C3/H4C2/DPY30/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR 159 -0.4190631 -1.624098 0.0003693 0.0050441 0.0041571 4815 TDP1/RAD51/XRCC4/XRCC5/H4C8/RAD50/ATR/LIG3/XRCC1/RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/ERCC4/H2AX/EME1/H2BC6/TIMELESS/H4C5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/CHEK2/WRN/RAD52/H4C6/RAD51B/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CCNA2/CHEK1/DNA2/H2BC11/RPA3/POLE2/H2BC15/BRCA1/H4C4/XRCC2/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/POLQ/H4C13/H4C9/RAD51AP1/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE 70 -0.5354568 -1.827494 0.0004090 0.0055214 0.0045504 3961 H2AC8/H4C8/RAD50/CDKN1B/H2AC6/H2BC8/H2BC12/EP400/H1-3/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MRE11/H2BC9/CCNA2/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H1-5/H2BC14/H2BC10/LMNB1/H1-1/H2BC17/CCNE2
REACTOME_ION_CHANNEL_TRANSPORT 137 0.4580825 1.674726 0.0004391 0.0058597 0.0048293 1982 ANO1/TRPV6/TRPM6/ATP12A/CASQ2/SLC9B2/SGK1/TTYH2/ANO2/ATP6V1C2/SLC9B1/ATP6V0D2/CLIC2/ANO4/STOM/SCNN1D/FXYD6/RIPK3/ATP11A/ANO8/TRPV3/ATP6V0A2/ATP8B1/ATP13A5/ATP8A2/CLCN6/TRPM4/ANO7/FKBP1B/ATP1B1/TPCN2/MLKL/ATP13A2/ANO9/RYR3/ATP6V1E2
REACTOME_INTERLEUKIN_1_SIGNALING 99 0.4995373 1.738477 0.0005533 0.0072690 0.0059908 5127 IL1R2/NOD2/IL1A/NFKB2/IL1RN/IRAK2/NFKBIA/MYD88/PSMA6/IRAK1/RIPK2/MAP3K8/PSMC4/NFKBIB/SQSTM1/IRAK4/RELA/NOD1/PSMD11/MAP2K1/PSMD7/IKBKG/PSMB2/PSMD3/PELI3/NKIRAS2/PSMB8/PSMD14/PSMC1/TOLLIP/PSMA2/TNIP2/PSMB9/PSMD1/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PELI1/PSMD13/SEM1/PSMB7/PSMD2/SAA1/PSME4/PSMA3
REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING 117 0.4800937 1.719816 0.0005572 0.0072690 0.0059908 5127 RASGRP1/LAT2/PRKCQ/FOS/ITPR3/NFKBIA/CARD11/PSMA6/GAB2/KRAS/FYN/RAC1/TEC/PSMC4/NRAS/BCL10/JUN/RELA/PAK2/PSMD11/ITPR2/SYK/VAV2/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/LYN/MALT1/PSMD1/PLCG1/CDC34/PSMB6/TAB3/PSMD8/PIK3CB/MAPK1/PSME3/MAPK3/TAB2/SHC1/PSME2/GRB2/PSMF1/PSMA7/HRAS/PSMC5/MAPK9/PSMD12/NFKB1/PSMD9/PAK1/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3
REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC 25 0.6937737 1.863579 0.0006125 0.0079018 0.0065123 4292 TAP2/TAP1/SEC23A/SEC13/HLA-F/HLA-C/SEC31A/TAPBP/SEC24D/HLA-G/HLA-A/CALR/SEC24A/HLA-B/SEC24C/HLA-E/HSPA5/ERAP1/PDIA3/ERAP2
REACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING 10 0.8484964 1.858584 0.0008057 0.0102112 0.0084156 1080 CD274/PRDM1/IL2RG/HIF1A
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 175 0.4333897 1.637975 0.0008092 0.0102112 0.0084156 2497 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC5A1/SLC39A8/SLC2A6/SLC24A3/SLC5A8/SLC7A11/SLCO4A1/SLCO1B1/SLC6A14/SLC3A2/SLC29A2/SLC7A9/SLC12A2/SLC7A5/SLC7A1/SLC28A3/SLC1A5/SLC5A3/SLC4A9/SLC36A1/SLCO1B3/SLC26A6/SLC26A11/SLC1A4/SLCO3A1/SLC27A4/SLC4A3/SLC38A1/SLCO4C1/AHCYL2/SLC15A3/SLC5A12/SLC12A4/SLC35C1/SLC39A1/SLC16A7/SLC9A1/SLC6A9/SLC17A5/SLC9A4/SLC8A1/SLC8B1/SLC39A4/SLC16A3/SLC39A14/SLC35D2/SLC25A22/SLC35B4/SLC39A7/SLC6A11/SLC29A4/SLC20A2/SLC50A1/RUNX1/SLC9A7
REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 24 0.6969385 1.849807 0.0008416 0.0105070 0.0086594 1486 WARS1/GARS1/MARS1/YARS1/AARS1/TARS1/IARS1/SARS1/EPRS1
REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE 72 -0.5048914 -1.732447 0.0008664 0.0105883 0.0087264 3762 TP53BP1/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/CHEK2/H4C6/H2BC4/BARD1/H4C3/H4C2/MRE11/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2BC14/H2BC10/H2BC17
REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 109 0.4797223 1.712708 0.0008574 0.0105883 0.0087264 3274 PHOSPHO1/PLA2G3/PNPLA3/ACHE/LPIN1/MFSD2A/PLA2G4C/ABHD4/PLAAT1/LIPH/PLA2G4A/GPCPD1/GPAT3/LPCAT4/GPD2/PISD/PTPMT1/SELENOI/CPNE3/GPAT4/TAFAZZIN/CSNK2B/ACP6/MBOAT1/PLD2/PTDSS1/LPIN2/PITPNM2/PITPNB/LPIN3/ABHD3/OSBPL5/MIGA2/PLA2G15/MGLL/PNPLA2/AGPAT3
REACTOME_CILIUM_ASSEMBLY 184 -0.3809081 -1.512139 0.0008827 0.0106752 0.0087980 3775 CEP57/UNC119B/HAUS1/ARL6/CEP41/TCTN1/HSP90AA1/IFT20/CEP250/TUBA4B/CEP164/CEP43/IQCB1/KIF3A/ARL13B/DYNLT2B/IFT46/BBS10/CEP135/IFT22/ARL3/DYNC2I1/BBS9/CLUAP1/TMEM216/BBIP1/IFT122/IFT43/TCTN2/BBS2/CNTRL/WDR19/CENPJ/KIF17/KIF24/DYNC2LI1/TMEM67/B9D1/PCM1/CEP83/CEP76/CEP97/CCP110/IFT57/IFT140/CEP162/IFT27/CC2D2A/IFT88/IFT52/IFT74/NPHP1/BBS12/CNGA4/CETN2/IFT81/RPGRIP1L/WDR35/IFT172/IFT80/DYNC2H1/MKS1/B9D2/DYNLT2/LZTFL1/CEP78/CEP70/BBS4/DYNLRB2/TTC21B/PRKAR2B/NEK2/PLK1/PLK4/CDK1
REACTOME_SYNTHESIS_OF_PC 25 0.6739735 1.810392 0.0010740 0.0128545 0.0105941 439 PHOSPHO1/ACHE/LPIN1/MFSD2A
REACTOME_TRYPTOPHAN_CATABOLISM 12 0.8131124 1.859454 0.0011985 0.0141985 0.0117017 709 IDO2/KYAT1/HAAO/IDO1/SLC3A2/SLC7A5
REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS 49 0.5925193 1.851894 0.0013214 0.0154969 0.0127718 1907 B3GNT6/GCNT3/MUC21/GALNT4/MUC3A/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ST3GAL4/B3GNT8/MUC1/MUC4
REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION 74 0.5224813 1.763508 0.0013488 0.0156591 0.0129055 6112 RASGRP1/PRKCQ/NFKBIA/CARD11/PSMA6/PSMC4/BCL10/RELA/PSMD11/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/LYN/MALT1/PSMD1/CDC34/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3/PSMA1/UBC/UBE2D2/BTRC/TAB1/PSMC3/TRAF6/IKBKB/UBE2V1/PDPK1
REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS 73 -0.4827062 -1.657787 0.0015438 0.0177459 0.0146254 1585 GSTM2/SULT1E1/GSTM1/UGT1A7/UGT1A5/UGT3A2/SULT1B1/SLC26A1/ACSM1/GSTA3/UGT1A8/NAT1/GSTA4/UGT2A1/GSTA1/GSTA2
REACTOME_INTERLEUKIN_10_SIGNALING 33 0.6524401 1.890235 0.0017235 0.0196176 0.0161679 1546 IL1R2/CXCL10/CCL4/CXCL8/CCL22/IL1A/CD86/IL1RN/PTGS2/CXCL1/ICAM1/TNF/LIF/PTAFR/CCL5/CXCL2
REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 78 0.5137581 1.752965 0.0017550 0.0197823 0.0163036 1831 SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC24A3/SLC5A8/SLC7A11/SLC6A14/SLC3A2/SLC7A9/SLC12A2/SLC7A5/SLC7A1/SLC1A5/SLC4A9/SLC36A1/SLC26A6/SLC26A11/SLC1A4/SLC4A3/SLC38A1/AHCYL2/SLC15A3/SLC5A12/SLC12A4/SLC9A1/SLC17A5/SLC9A4/SLC8A1/SLC8B1
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 130 -0.4092749 -1.536127 0.0018198 0.0203156 0.0167432 1642 H3C13/KIF19/KIF22/KIF18A/PRKACB/KIF26B/KIF11/H3C10/KIFC1/KIF21A/KIF4A/PRKAR2B/KIF20B/GATA2/H3C7/MYB/H3C12/CENPE/KIF15/KIF2C/KIF20A/H3C3/HBB/KIF18B/H3C8/H3C2
REACTOME_DISEASES_OF_DNA_REPAIR 34 -0.6007858 -1.786260 0.0018579 0.0204501 0.0168540 3602 MUTYH/RAD51/RAD50/NEIL1/RMI1/MSH6/NTHL1/ATM/BRCA2/WRN/OGG1/MSH2/RAD51B/BARD1/MSH3/MRE11/DNA2/BRCA1/XRCC2/BLM/BRIP1/RAD51AP1/EXO1/NEIL3
REACTOME_STIMULI_SENSING_CHANNELS 79 0.5027272 1.720954 0.0018671 0.0204501 0.0168540 1936 ANO1/TRPV6/TRPM6/CASQ2/SLC9B2/SGK1/TTYH2/ANO2/SLC9B1/CLIC2/ANO4/STOM/SCNN1D/RIPK3/ANO8/TRPV3/CLCN6/TRPM4/ANO7/FKBP1B/TPCN2/MLKL/ANO9/RYR3
REACTOME_TRNA_AMINOACYLATION 41 0.5901755 1.795637 0.0019425 0.0208816 0.0172096 1486 WARS1/GARS1/MARS1/YARS1/AARS1/TARS1/IARS1/SARS1/EPRS1
REACTOME_HCMV_INFECTION 141 -0.4072971 -1.552144 0.0019337 0.0208816 0.0172096 2260 NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE 42 -0.5554177 -1.727075 0.0020411 0.0217401 0.0179172 4547 RAD50/ATR/RAD9A/TOPBP1/RPA1/RMI1/RAD9B/ATM/BRCA2/RFC3/WRN/RAD51B/BARD1/RFC5/MRE11/CHEK1/DNA2/RPA3/BRCA1/XRCC2/BLM/BRIP1/RAD51AP1/EXO1
REACTOME_SIGNALLING_TO_RAS 19 0.7315494 1.847913 0.0021248 0.0224261 0.0184826 2689 NTRK1/MAPKAPK3/MAPK12/MAPK11/KRAS/NRAS/MAPKAPK2/SHC2/SRC/MAPK13/RALA
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 110 -0.4337667 -1.589391 0.0021643 0.0226379 0.0186571 5794 RPLP0/RPL26L1/RPL17/RPS11/RPL19/RPS16/RPL12/RPL10/RPS28/RPS27A/RPS9/RPS10/RPL27/SRP14/RPL39/RPS19/RPS3/RPSA/RPL41/RPL9/RPL7A/RPL37A/RPS27/RPS2/RPS29/RPS24/RPS5/RPS8/RPS15A/RPL36A/RPS21/RPS20/RPL34/RPL13/RPL24/RPS13/RPS12/RPL23A/RPS7/RPS23/RPL27A/RPL3/RPL32/RPL30/RPL29/RPL21/RPL31/RPL14/RPL13A/RPS6/RPL6/RPS14/RPL11/RPL37/RPS25/RPL35A/RPL22/SRP9/RPL7/RPS18/RPL23/RPL4/RPS4X/RPL10A/RPS4Y1/RPL39L/SRPRB/RPL26/RPL15/RPL5/RPS3A
REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA 37 -0.5773343 -1.764814 0.0022149 0.0227569 0.0187552 4801 RAD51/RAD50/ATR/RAD9A/TOPBP1/RPA1/RMI1/ERCC4/RAD9B/ATM/RFC3/WRN/RAD52/BARD1/RFC5/MRE11/ERCC1/DNA2/RPA3/BRCA1/BLM/BRIP1/EXO1
REACTOME_DNA_REPAIR 319 -0.3327307 -1.390761 0.0022071 0.0227569 0.0187552 4094 NEIL2/RPA1/MCRS1/ERCC5/POLR2I/H2BC12/RMI1/UNG/RUVBL1/ACTL6A/TP53BP1/ERCC4/H2AX/EME1/MSH6/NTHL1/H2BC6/TIMELESS/MGMT/H4C5/FANCL/GTF2H5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/ALKBH2/CHEK2/H2AJ/WRN/RAD52/OGG1/MSH2/H4C6/RAD51B/FANCM/H2BC4/BARD1/H2AZ2/MSH3/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CENPS/CETN2/CCNA2/CHEK1/DNA2/FANCI/H2BC11/RPA3/POLE2/POLI/H2BC15/LIG1/BRCA1/H4C4/XRCC2/UBE2T/H4C1/H2AC4/FANCB/ABRAXAS1/BLM/POLN/BRIP1/H2BC7/H2BC3/INO80B/POLQ/H4C13/FTO/H4C9/CHD1L/RAD51AP1/H2BC13/EXO1/H2AC14/PCLAF/H2BC14/H2BC10/H2BC17/DTL/NEIL3
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION 228 0.3775087 1.475147 0.0022916 0.0233385 0.0192345 2514 CAPN14/EMILIN2/VWF/LOXL4/MMP1/ITGA10/COL6A1/COL13A1/SDC2/KLK7/ADAMTS14/CD44/ADAM8/MMP16/LUM/NID2/CAPN12/TNC/MMP19/SDC3/FGF2/CD47/MMP25/MATN3/ADAM9/PXDN/MMP17/COLGALT2/TIMP2/CEACAM1/ITGB8/KDR/ICAM1/LAMA4/DDR2/ADAMTS9/ITGA9/BMP2/MMP11/THBS1/COL22A1/ITGA6/ITGAM/LOX/COL17A1/SERPINH1/MMP10/ITGAV/LAMB3/PLOD3/COLGALT1/BMP1/COL14A1/LTBP4/ITGB7/TIMP1/ITGB6/FURIN/CAPN2/SPP1/LAMB1/ADAM17/P4HA2/ITGA3/CD151/PLEC/COL5A2/ACTN1
REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS 13 0.7712075 1.801150 0.0025030 0.0250520 0.0206467 2 NTRK1
REACTOME_G0_AND_EARLY_G1 27 -0.6303936 -1.788322 0.0024834 0.0250520 0.0206467 2188 LIN9/TFDP2/CCNA2/CDC25A/E2F1/CCNE2/CDK1/TOP2A/MYBL2
REACTOME_SIGNALLING_TO_ERKS 32 0.6490895 1.873176 0.0026349 0.0261467 0.0215489 4622 NTRK1/MAPKAPK3/MAPK12/MAPK11/KRAS/NRAS/MAPKAPK2/SHC2/SRC/MAPK13/MAP2K1/RALA/RAP1A/CRK/MAP2K2/KIDINS220/MAPK1/RIT1/MAPK3/RALB/SHC1/GRB2/HRAS
REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS 62 0.5277129 1.720474 0.0031192 0.0306895 0.0252929 914 LY6G6C/THY1/RAET1L/LYPD1/PLAUR/NTNG1/RAET1G/ALPL/CEACAM5/LY6K/ULBP2
REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING 126 0.4418600 1.605762 0.0032467 0.0316762 0.0261061 5127 IL1R2/IL1RL1/IL36G/NOD2/IL36A/IL1A/NFKB2/IL1RN/IL18R1/IRAK2/NFKBIA/MYD88/PSMA6/IL1RL2/IRAK1/RIPK2/PTPN9/MAP3K8/PSMC4/NFKBIB/SQSTM1/IRAK4/RELA/PTPN11/NOD1/PSMD11/PTPN12/MAP2K1/ALOX5/PSMD7/IKBKG/PSMB2/PSMD3/PELI3/NKIRAS2/PTPN23/PSMB8/PSMD14/PSMC1/IL18BP/TOLLIP/PSMA2/TNIP2/PSMB9/PTPN18/PSMD1/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PELI1/PSMD13/SEM1/PSMB7/PSMD2/SAA1/PSME4/PSMA3
REACTOME_NICOTINAMIDE_SALVAGING 16 0.7399894 1.788946 0.0033290 0.0322083 0.0265445 3132 SLC5A8/NNMT/PARP9/PTGS2/NAMPT/PARP14/PARP10/PARP6/NAPRT/PARP4
REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION 13 0.7585417 1.771569 0.0034616 0.0329423 0.0271495 9 NOS2
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 53 0.5411698 1.710513 0.0034433 0.0329423 0.0271495 2943 NOD2/AIM2/BCL2/NFKB2/IRAK2/MAPK12/HMOX1/MAPK11/CARD9/TXN/IRAK1/RIPK2/TNFAIP3/RELA/CYLD/NOD1/BIRC3/MAPK13/IKBKG/CASP2
REACTOME_HYALURONAN_METABOLISM 14 0.7566294 1.781890 0.0036892 0.0348227 0.0286992 757 HAS2/HYAL1/CEMIP/CD44/HAS3/HYAL3
REACTOME_RAB_REGULATION_OF_TRAFFICKING 115 0.4459277 1.597028 0.0039039 0.0365520 0.0301245 5503 DENND4A/RIC1/RAB32/RAB8B/RAB31/OPTN/RINL/TBC1D24/DENND5A/AKT3/TBC1D14/RAB9A/RAB35/TBC1D10A/DENND3/AKT1/DENND4C/RAB6A/HPS1/RAB5B/GGA3/RGP1/TBC1D20/TBC1D16/MON1A/RAB3IP/TRAPPC10/CCZ1/TSC1/MAP1LC3B/TRAPPC6A/TBC1D10B/RAB8A/RAB11A/RAB3A/MON1B/RAB21/RABGAP1/ANKRD27/ARF6/RAB5C/RAB7A/TBC1D7/SBF1/CCZ1B/DENND2C/SYTL1/RAB10/TBC1D25/DENND5B/RAB14/RAB18/RAB5A/DENND4B/GGA2/DENND1A/RAB3GAP2/TRAPPC12/SBF2/RAB27A/RAB12/GDI1/RAB1A/RABEP1/TBC1D13/TRAPPC2/ULK1/TRAPPC1/RAB33B/MADD/TRAPPC9
REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION 14 -0.7221659 -1.732056 0.0040090 0.0368576 0.0303763 867 CCNB1/CCNB2/PLK1/CDK1
REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY 69 0.5042976 1.681852 0.0040318 0.0368576 0.0303763 5850 DLX5/PPARGC1B/RUNX2/MSX2/PSMA6/BMP2/STAT1/PSMC4/PSMD11/HIVEP3/PPARGC1A/PSMD7/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/PSMD1/PSMB6/PSMD8/PSME3/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/GSK3B/PSMD9/STUB1/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3/PSMA1/CBFB/UBC/WWP1/TWIST1/ESRRA/PSMC3
REACTOME_BIOLOGICAL_OXIDATIONS 158 -0.3846918 -1.489908 0.0040049 0.0368576 0.0303763 1934 UGT1A4/CYP4B1/CYP27A1/PTGS1/GSTM2/SULT1E1/GSTM1/ALDH2/ADH7/ALDH1A1/UGT1A7/CYP2C8/UGT1A5/UGT3A2/CYP2W1/FMO3/SULT1B1/CYP4F3/CYP39A1/MTARC1/SLC26A1/ACSM1/ACSS1/GSTA3/POMC/EPHX1/CYP24A1/DPEP2/CYP2B6/UGT1A8/NAT1/CYP2F1/ADH6/CYP4A22/FMO2/CYP2A6/ALDH3A1/GSTA4/CYP26B1/UGT2A1/GSTA1/GSTA2
REACTOME_METALLOPROTEASE_DUBS 30 -0.5918390 -1.718189 0.0041518 0.0376580 0.0310360 2089 STAMBPL1/BARD1/H2AC15/BRCA1/H2AC4/ABRAXAS1/H2AC16/H2AC13/H2AC11/H2AC21/H2AC14/H2AC12
REACTOME_BASIGIN_INTERACTIONS 20 0.6926358 1.770445 0.0042623 0.0380153 0.0313304 2847 MMP1/SLC7A11/SLC3A2/SLC7A9/SLC7A5/ITGA6/ATP1B1/SLC16A3/ITGA3/CAV1
REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 80 0.4940431 1.699162 0.0042894 0.0380153 0.0313304 2634 MX2/ISG15/OAS3/OASL/OAS1/MX1/IFIT1/USP18/OAS2/UBE2L6/HERC5/STAT1/EIF2AK2/TRIM25/NUP188/EIF4E3/SEC13/NEDD4/EIF4G1/PDE12
REACTOME_PHOSPHOLIPID_METABOLISM 185 0.3974143 1.510926 0.0042298 0.0380153 0.0313304 4865 PHOSPHO1/PLA2G3/PNPLA3/ACHE/LPIN1/MFSD2A/PLA2G4C/ABHD4/ENPP6/PLAAT1/LIPH/PLA2G4A/GPCPD1/GPAT3/LPCAT4/GPD2/PISD/PLEKHA6/PTPMT1/SELENOI/CPNE3/PLEKHA2/GPAT4/PIP4K2A/TAFAZZIN/CSNK2B/ACP6/GDPD3/PIP5K1A/MBOAT1/PIK3C2B/PLD2/MTMR12/INPPL1/PTDSS1/PIP4P1/LPIN2/PITPNM2/PITPNB/LPIN3/ABHD3/OSBPL5/INPP5J/MIGA2/PIP4K2C/PLA2G15/PI4K2A/MGLL/ARF3/INPP5F/PLEKHA5/PNPLA2/AGPAT3/INPP5D/CPNE1/PIP5K1C/SYNJ1/HADHA/PIK3CB/SBF1/LPCAT1/DGAT1/PLAAT3/RAB14/MBOAT7/SYNJ2/OCRL/PCYT2/GDE1/RAB5A/OSBPL8/PLEKHA1/PCYT1A/CSNK2A2/DDHD2/STARD10/ARF1/PIKFYVE/INPP5K/PNPLA6/AGPAT2/PNPLA8/CSNK2A1/SBF2/PI4KB
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE 69 0.4996181 1.666245 0.0043886 0.0385996 0.0318120 1281 SPRR2E/RPTN/SPRR3/SPRR2F/SPRR2A/KRT16/PCSK6/SPRR1A/KRT23/KRT24/SPRR2D/KRT40/CSTA/KLK12/KRT6A/KRT78/PI3/LCE1E/KRT8/PKP2/KRT18/PRSS8
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION 147 -0.3890603 -1.490909 0.0044521 0.0388641 0.0320300 2188 LIN9/CDKN2C/TFDP2/CCNA2/TK1/DHFR/RPA3/POLE2/CDC7/MCM8/TYMS/CDC25A/POLA2/FBXO5/CCNB1/ORC1/E2F1/E2F2/CDT1/GMNN/CCNE2/CDK1/RRM2/MCM10/TOP2A/MYBL2
REACTOME_O_LINKED_GLYCOSYLATION 85 0.4765247 1.658298 0.0045608 0.0395158 0.0325671 1907 B3GNT6/GCNT3/THSD7A/MUC21/ADAMTS14/GALNT4/MUC3A/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ADAMTSL3/ADAMTS9/ADAMTS17/ST3GAL4/THBS1/B3GNT8/MUC1/MUC4
REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY 15 0.7556324 1.795113 0.0046385 0.0396281 0.0326596 2725 TRIB3/CHAC1/ASNS/DDIT3/ATF4/GRB10/CEBPG/ATF3/EIF2S2/ATF5
REACTOME_PEPTIDE_HORMONE_METABOLISM 53 0.5316861 1.680537 0.0046762 0.0396281 0.0326596 949 DPP4/INHBE/ACHE/MME/KLF4/PAX6/ACE/ANPEP/PLA2G7/STX1A
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 79 0.4790959 1.640059 0.0046645 0.0396281 0.0326596 5127 RASGRP1/NFKBIA/CARD11/PSMA6/KRAS/NFKBIE/PSMC4/NRAS/NFKBIB/BCL10/RELA/PSMD11/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/FKBP1A/PPIA/PSMB9/MALT1/PSMD1/PSMB6/PSMD8/PSME3/RASGRP3/PSME2/PSMF1/PSMA7/HRAS/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3
REACTOME_NGF_STIMULATED_TRANSCRIPTION 36 0.6105726 1.808003 0.0048102 0.0404688 0.0333525 1941 ARC/SGK1/FOS/F3/FOSB/EGR1/EGR2/TRIB1/FOSL1/ASCL1/ID3/JUND/JUNB
REACTOME_SIGNALING_BY_VEGF 99 0.4545217 1.581815 0.0050038 0.0417942 0.0344448 4007 NCF1/TRIB3/FLT1/MAPKAPK3/VEGFA/ITPR3/NRP2/MAPK12/KDR/SPHK1/MAPK11/KRAS/BCAR1/FYN/AXL/NCF2/ITGAV/RAC1/AKT3/ACTB/NRAS/AKT1/MAPKAPK2/SHC2/SRC/PRR5/PAK2/MAPK13/ITPR2/ACTG1/VAV2/NCF4/CAV1/ELMO2/CRK/WASF1/VEGFD/PRKCA/NCKAP1/JUP/PLCG1/ABI1/MTOR/PIK3CB/CYFIP1/CTNNA1
REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE 14 0.7439570 1.752046 0.0051219 0.0424751 0.0350060 1466 SLC18A2/MAOA/STX1A/PPFIA3/SYT1
REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1 10 0.7907963 1.732195 0.0052550 0.0432699 0.0356610 351 DPP4/PAX6
REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES 11 -0.7473337 -1.671638 0.0056947 0.0465606 0.0383731 2332 SMC4/SMC2/CCNB1/CCNB2/NCAPH/CDK1/NCAPG
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 29 -0.5668830 -1.623894 0.0060854 0.0494068 0.0407188 2188 LIN9/TFDP2/TK1/DHFR/TYMS/CDC25A/FBXO5/ORC1/E2F1/CDT1/CDK1/RRM2

GOMF

ID setSize enrichmentScore NES pvalue p.adjust qvalue rank core_enrichment
REACTOME_CHOLESTEROL_BIOSYNTHESIS 24 0.9100095 2.415338 0.0000000 0.0000000 0.0000000 887 CYP51A1/MVD/ACAT2/HMGCS1/EBP/FDPS/LSS/DHCR7/MSMO1/HMGCR/HSD17B7/IDI1/FDFT1/SQLE/NSDHL/SC5D/TM7SF2/MVK
REACTOME_CELL_CYCLE_CHECKPOINTS 281 -0.4899724 -2.015469 0.0000000 0.0000000 0.0000000 2032 CENPH/CENPS/CCNA2/CENPU/CHEK1/DNA2/B9D2/CENPM/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/CDC7/MCM8/KIF18A/PKMYT1/ABRAXAS1/CDC25A/BLM/BRIP1/SPC24/H2BC7/H2BC3/ANAPC4/CCNB1/ORC1/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/EXO1/SGO2/H2BC14/NDC80/H2BC10/MAD2L1/CENPF/CCNB2/H2BC17/CENPE/NUF2/CCNE2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/MCM10/ERCC6L/CDC20/GTSE1/CDC25C/UBE2C/BUB1B/SPC25
REACTOME_M_PHASE 390 -0.4453607 -1.894092 0.0000000 0.0000000 0.0000000 2064 SMC2/CENPH/H3C11/CENPS/CETN2/H3C1/CENPU/VRK1/B9D2/ESPL1/CENPM/H2BC11/H3C13/CEP78/H2BC15/CEP70/H4C4/H4C1/H2AC4/KIF18A/H3C10/SPC24/H2BC7/FBXO5/H2BC3/ANAPC4/CCNB1/H4C13/CENPK/H4C9/PTTG1/CENPP/PRKAR2B/H2BC13/KNL1/H2AC14/SGO2/CDCA5/H2BC14/NDC80/H2BC10/LMNB1/MAD2L1/CENPF/H3C7/CCNB2/NCAPH/H2BC17/H3C12/CENPE/NEK2/NUF2/PLK1/PLK4/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/KIF20A/CDC20/H3C3/NCAPG/UBE2C/H3C8/BUB1B/SPC25/H3C2
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP 42 0.7926678 2.421620 0.0000000 0.0000003 0.0000002 887 CYP51A1/MVD/HMGCS1/FDPS/ELOVL6/LSS/DHCR7/HMGCR/IDI1/HELZ2/FDFT1/SQLE/SCD/SC5D/FASN/TM7SF2/MVK
REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES 61 -0.6985479 -2.328780 0.0000000 0.0000003 0.0000002 3700 H2AX/H3C6/H2BC6/NCAPD3/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SMC4/H2BC9/SMC2/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/PLK1/CDK1/H3C3/H3C8/H3C2
REACTOME_MITOTIC_SPINDLE_CHECKPOINT 108 -0.6067154 -2.222323 0.0000000 0.0000004 0.0000003 1009 CENPH/CENPS/CENPU/B9D2/CENPM/KIF18A/SPC24/ANAPC4/CENPK/CENPP/KNL1/SGO2/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_DNA_REPLICATION 176 -0.5163359 -2.046794 0.0000000 0.0000010 0.0000009 2017 H3C11/H3C1/CCNA2/DNA2/H2BC11/H3C13/RPA3/POLE2/H2BC15/LIG1/H4C4/H4C1/CDC7/H2AC4/MCM8/GINS1/GINS2/POLA2/H3C10/H2BC7/H2BC3/ANAPC4/ORC1/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/CDT1/GMNN/H2BC14/H2BC10/H3C7/H2BC17/H3C12/CCNE2/MCM10/H3C3/UBE2C/H3C8/H3C2
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 63 -0.6768095 -2.275381 0.0000000 0.0000011 0.0000009 3971 NPM1/H2BC12/RBBP4/ITGB3BP/RUVBL1/RBBP7/CENPC/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MIS18A/H2BC9/MIS18BP1/CENPH/CENPS/CENPU/CENPM/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/H2AC14/H2BC14/H2BC10/CENPW/H2BC17/OIP5/HJURP
REACTOME_HDACS_DEACETYLATE_HISTONES 81 -0.6372707 -2.229347 0.0000000 0.0000011 0.0000009 2162 H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA 61 -0.6767456 -2.256096 0.0000000 0.0000014 0.0000011 3961 H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/PHF19/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RMTS_METHYLATE_HISTONE_ARGININES 66 -0.6627525 -2.232308 0.0000000 0.0000014 0.0000011 3831 RBBP7/ACTL6A/H2AX/H3C6/H4C5/SMARCA2/SMARCE1/H4C12/WDR77/H2AJ/H4C6/H2AZ2/H4C3/H4C2/H2AC15/H3C11/H3C1/H3C13/H4C4/H4C1/H2AC4/H3C10/H2AC16/SMARCD3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2AC14/H2AC12/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_MEIOSIS 95 -0.6002354 -2.158029 0.0000000 0.0000014 0.0000011 3813 H3-3A/SYCP2/H2AX/H3C6/H2BC6/H4C5/ATM/BRCA2/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SYNE1/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/DMC1/H3C3/H3C8/H3C2
REACTOME_CHROMOSOME_MAINTENANCE 126 -0.5583225 -2.075482 0.0000000 0.0000014 0.0000011 4152 H2BC8/PRIM1/POLA1/RPA1/NPM1/POLR2I/H2BC12/RBBP4/ITGB3BP/RUVBL1/RBBP7/H3-3A/CENPC/H2AX/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/POLD1/RFC3/WRAP53/H2AJ/WRN/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/MIS18A/H2BC9/CHTF8/MIS18BP1/CENPH/CENPS/CCNA2/CENPU/DNA2/CENPM/H2BC11/RPA3/H2BC15/LIG1/H4C4/H4C1/H2AC4/BLM/POLA2/H2BC7/H2BC3/H4C13/CENPK/H4C9/CENPP/H2BC13/KNL1/H2AC14/DSCC1/H2BC14/H2BC10/CENPW/H2BC17/OIP5/HJURP
REACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION 64 -0.6735249 -2.256106 0.0000000 0.0000014 0.0000011 3961 H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION 56 -0.6751004 -2.208585 0.0000000 0.0000016 0.0000013 4003 SUV39H1/H2BC12/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF 55 0.7512270 2.404642 0.0000000 0.0000016 0.0000013 887 CYP51A1/MVD/HMGCS1/FDPS/ELOVL6/LSS/DHCR7/HMGCR/INSIG1/IDI1/HELZ2/FDFT1/SQLE/SCD/SC5D/FASN/TM7SF2/MVK
REACTOME_MEIOTIC_RECOMBINATION 70 -0.6618302 -2.258802 0.0000000 0.0000016 0.0000013 3700 H2AX/H3C6/H2BC6/H4C5/ATM/BRCA2/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/DMC1/H3C3/H3C8/H3C2
REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 54 0.7385567 2.350001 0.0000000 0.0000017 0.0000014 1781 SOCS1/IFIT2/MX2/RSAD2/ISG15/OAS3/ISG20/OASL/IFIT3/OAS1/MX1/IFIT1/IFI35/IFITM1/USP18/IFI6/EGR1/IRF7/BST2/IFI27/XAF1/OAS2/IFITM3/SOCS3/IFIT5/IRF6/ADAR/STAT1
REACTOME_HATS_ACETYLATE_HISTONES 128 -0.5551664 -2.075388 0.0000000 0.0000017 0.0000014 4152 H2BC8/H2BC18/MSL3/MCRS1/MORF4L1/H2BC12/KAT2A/EP400/RUVBL1/RBBP7/ACTL6A/ELP6/H3C6/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/HAT1/H4C6/H2BC4/ING4/H4C3/H4C2/JADE1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 26 -0.8200483 -2.306116 0.0000000 0.0000019 0.0000016 871 ANAPC4/MAD2L1/NEK2/CDC20/UBE2C/BUB1B
REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3 53 -0.6949488 -2.285318 0.0000000 0.0000019 0.0000016 3700 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/AR/H3C3/H3C8/H3C2
REACTOME_RHO_GTPASE_EFFECTORS 290 -0.4445913 -1.840399 0.0000000 0.0000020 0.0000016 1023 H3C10/SPC24/H2BC7/MYLK/S100A9/H2BC3/CYBB/H4C13/CENPK/H4C9/WAS/S100A8/DIAPH3/CENPP/H2BC13/KNL1/H2AC14/SGO2/CIT/NOX1/H2BC14/NDC80/KIF14/H2BC10/MAD2L1/CENPF/H3C7/H2BC17/H3C12/CENPE/NUF2/PLK1/SGO1/IQGAP3/SKA1/BIRC5/AR/KIF2C/BUB1/ERCC6L/CDC20/H3C3/CDC25C/H3C8/BUB1B/SPC25/H3C2
REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION 57 -0.6786559 -2.227959 0.0000000 0.0000024 0.0000020 3700 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ORC1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_DNA_METHYLATION 52 -0.6918105 -2.263368 0.0000001 0.0000030 0.0000024 3813 H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION 98 -0.5865076 -2.124470 0.0000001 0.0000031 0.0000026 3961 H2BC12/POLR1C/KAT2A/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE 78 -0.6253839 -2.173370 0.0000001 0.0000032 0.0000026 3961 H2BC12/POLR1C/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX 78 -0.6238631 -2.168085 0.0000001 0.0000036 0.0000030 3852 RUVBL1/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/PYGO1/H2AJ/TCF4/H4C6/H2BC4/H2AZ2/BCL9/H4C3/H4C2/H2BC9/RUNX3/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/AXIN2/H2BC13/H2AC14/TCF7/LEF1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS 95 -0.5820628 -2.092693 0.0000001 0.0000047 0.0000039 3967 POLR2I/H2BC12/H3-3A/H2AX/H3C6/H2BC6/H4C5/H2BC5/H4C12/NUP37/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/NDC1/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS 21 -0.8388424 -2.252758 0.0000002 0.0000067 0.0000055 871 ANAPC4/MAD2L1/CDC20/UBE2C/BUB1B
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION 115 -0.5579830 -2.062884 0.0000002 0.0000095 0.0000079 1009 SPC24/CCNB1/CENPK/CENPP/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CCNB2/CENPE/NUF2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/BUB1B/SPC25
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 97 -0.5690216 -2.050953 0.0000003 0.0000107 0.0000089 2866 H4C6/H2BC4/NOTCH1/MAML3/H2AZ2/H4C3/H4C2/H2BC9/NOTCH3/H3C11/TFDP2/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/ATP2A3/H2BC13/H2AC14/E2F1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/ST3GAL6/MIR449C/H3C3/H3C8/H3C2
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS 74 -0.6270305 -2.152107 0.0000003 0.0000109 0.0000090 3700 H2AX/RXRA/H3C6/H2BC6/H4C5/DEK/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/TFDP2/H3C1/CEBPA/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/E2F1/FLI1/LEF1/H2BC14/GATA2/H2BC10/H3C7/MYB/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 96 -0.5724421 -2.062934 0.0000003 0.0000113 0.0000093 4003 SUV39H1/H2BC12/POLR1C/SUDS3/H3-3A/H2AX/H3C6/H2BC6/H4C5/GTF2H5/H2BC5/H4C12/TTF1/H2AJ/SAP30/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_REPRODUCTION 108 -0.5543982 -2.030692 0.0000004 0.0000129 0.0000106 2521 H4C3/H4C2/SYNE1/MRE11/H2BC9/H3C11/H3C1/H2BC11/H3C13/RPA3/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/PSMC3IP/BLM/H3C10/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/OVGP1/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/CATSPERD/DMC1/H3C3/H3C8/H3C2
REACTOME_HCMV_LATE_EVENTS 103 -0.5576692 -2.037416 0.0000004 0.0000130 0.0000107 2521 H4C3/H4C2/NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE 223 -0.4551216 -1.839857 0.0000004 0.0000133 0.0000110 1009 SPC24/FBXO5/ANAPC4/CCNB1/CENPK/PTTG1/CENPP/KNL1/SGO2/CDCA5/NDC80/LMNB1/MAD2L1/CENPF/CCNB2/CENPE/NUF2/PLK1/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH 89 -0.5836347 -2.066148 0.0000004 0.0000138 0.0000114 4152 H2BC8/PRIM1/POLA1/FOXO3/H2BC12/RBBP4/RBBP7/H3-3A/H2AX/H3C6/CDK5/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/CDC25A/POLA2/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/CAPNS2/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/H2BC17/H3C12/H3C3/CDC25C/H3C8/H3C2
REACTOME_MITOTIC_PROMETAPHASE 191 -0.4729286 -1.881723 0.0000005 0.0000151 0.0000124 1009 PCM1/PDS5B/CEP76/CCP110/SMC4/NME7/SMC2/CENPH/CENPS/CETN2/CENPU/B9D2/CENPM/CEP78/CEP70/KIF18A/SPC24/CCNB1/CENPK/CENPP/PRKAR2B/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CCNB2/NCAPH/CENPE/NEK2/NUF2/PLK1/PLK4/SGO1/CDK1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/NCAPG/BUB1B/SPC25
REACTOME_MITOTIC_PROPHASE 130 -0.5153263 -1.934169 0.0000006 0.0000164 0.0000135 2643 H2AZ2/PRKCB/H4C3/H4C2/SMC4/NDC1/H2BC9/SMC2/H3C11/H3C1/VRK1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H3C7/CCNB2/H2BC17/H3C12/PLK1/CDK1/H3C3/H3C8/H3C2
REACTOME_DNA_REPLICATION_PRE_INITIATION 133 -0.5226252 -1.969144 0.0000007 0.0000205 0.0000169 1665 H2BC11/H3C13/RPA3/POLE2/H2BC15/H4C4/H4C1/CDC7/H2AC4/MCM8/POLA2/H3C10/H2BC7/H2BC3/ORC1/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/CDT1/GMNN/H2BC14/H2BC10/H3C7/H2BC17/H3C12/MCM10/H3C3/H3C8/H3C2
REACTOME_INTERFERON_SIGNALING 170 0.5154131 1.942624 0.0000007 0.0000205 0.0000169 2535 SOCS1/IFIT2/MX2/RSAD2/ISG15/CD44/OAS3/ISG20/OASL/GBP5/IFIT3/OAS1/MX1/IFIT1/IFI35/IFITM1/USP18/IFI6/EGR1/IRF7/BST2/IFI27/XAF1/OAS2/PML/IFITM3/ICAM1/SOCS3/PTAFR/IFIT5/UBE2L6/TRIM14/IRF6/HERC5/ADAR/STAT1/TRIM21/EIF2AK2/TRIM25/NUP188/EIF4E3/TRIM45/SEC13/HLA-DQB2/GBP1/HLA-F/HLA-C/STAT2/NEDD4/EIF4G1/TRIM5/PTPN11/GBP4
REACTOME_PHOSPHORYLATION_OF_THE_APC_C 20 -0.8158156 -2.160935 0.0000010 0.0000284 0.0000234 871 ANAPC4/CCNB1/PLK1/CDK1/UBE2C
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS 178 -0.4707924 -1.862121 0.0000013 0.0000339 0.0000279 1009 SPC24/ANAPC4/CENPK/PTTG1/CENPP/KNL1/SGO2/CDCA5/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/UBE2C/BUB1B/SPC25
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B 24 -0.7811961 -2.161560 0.0000016 0.0000412 0.0000340 871 ANAPC4/CCNB1/CDK1/CDC20/UBE2C
REACTOME_B_WICH_COMPLEX_POSITIVELY_REGULATES_RRNA_EXPRESSION 79 -0.5910492 -2.059283 0.0000016 0.0000412 0.0000340 3961 H2BC12/POLR1C/KAT2A/H3-3A/H2AX/H3C6/H2BC6/H4C5/DEK/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_POSITIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION 94 -0.5712527 -2.057096 0.0000016 0.0000412 0.0000340 3961 H2BC12/POLR1C/KAT2A/RBBP4/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/DEK/H2BC5/H4C12/TTF1/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_BASE_EXCISION_REPAIR 81 -0.5794047 -2.026916 0.0000024 0.0000582 0.0000480 4574 H2AC8/H4C8/LIG3/H2AC6/XRCC1/APEX1/NEIL1/H2BC8/NEIL2/RPA1/H2BC12/UNG/H2AX/NTHL1/H2BC6/H4C5/H2BC5/H4C12/POLD1/RFC3/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/H2BC9/H2BC11/RPA3/POLE2/H2BC15/LIG1/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT 89 -0.5621227 -1.989993 0.0000024 0.0000591 0.0000487 4260 RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/H2AX/H2BC6/H4C5/RAD9B/ATM/H2BC5/H4C12/RFC3/CHEK2/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/H2BC9/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/CCNB1/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/H2BC17/CDK1/CDC25C
REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION 134 -0.5008421 -1.889252 0.0000036 0.0000846 0.0000697 4003 SUV39H1/H2BC12/POLR1C/KAT2A/RBBP4/SUDS3/RBBP7/H3-3A/H2AX/H3C6/H2BC6/H4C5/CBX3/GTF2H5/DEK/H2BC5/H4C12/TTF1/H2AJ/SAP30/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/TET1/H4C4/H4C1/H2AC4/PHF19/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS 16 -0.8401569 -2.091342 0.0000043 0.0000987 0.0000813 1178 PKMYT1/CDC25A/CCNB1/FOXM1/CENPF/CCNB2/PLK1/CDC25C/MYBL2
REACTOME_SIGNALING_BY_INTERLEUKINS 375 0.4114043 1.674962 0.0000047 0.0001064 0.0000877 2711 NOS2/CISH/IL19/SOCS1/IL1R2/IL13RA2/ALOX15/SERPINB2/MMP1/IL1RL1/CXCL10/CCL4/MAOA/IL32/IL12RB2/IL36G/NOD2/IL17C/CXCL8/CCL22/CD36/IL2RG/IL31RA/EBI3/FOS/MAPKAPK3/BCL2/IL36A/VEGFA/SOCS2/IL1A/FGF2/CLCF1/GATA3/CD86/NFKB2/IL1RN/ANXA1/HCK/OSMR/IFNLR1/STX1A/IL18R1/IRAK2/NFKBIA/STX3/HIF1A/PTGS2/CXCL1/IL23A/MYD88/ICAM1/TNF/LIFR/PSMA6/GAB2/SOCS3/DUSP3/IRS2/HMOX1/LIF/IL4R/DUSP7/PTAFR/MAPK11/CCL5/LGALS9/FYN/SOX2/CXCL2/ITGAM/PIM1/DUSP6/IL15RA/IL1RL2/STAT1/IRAK1/RIPK2/IL20RB/MUC1/TEC/PTPN9/JUNB/MAP3K8/IL15/PSMC4/TIMP1/BATF/NFKBIB/SQSTM1/CDKN1A/AKT1/JUN/MSN/RORA/MYC/INPPL1/IRAK4/STAT2/MAPKAPK2/RELA/STX4/PTPN11/CCL20/IL27RA/NOD1/CSF2/PAK2/IL6ST/STXBP2/PSMD11/PTPN12/MAP2K1/ALOX5/RALA/CFL1/SYK
REACTOME_GENE_SILENCING_BY_RNA 123 -0.5110819 -1.898076 0.0000056 0.0001240 0.0001022 3700 H2AX/HSP90AA1/H3C6/TDRD1/H2BC6/H4C5/H2BC5/H4C12/NUP37/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/HENMT1/NDC1/H2BC9/H3C11/H3C1/TDRD6/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/MIR23B/H3C10/H2BC7/H2BC3/PIWIL2/H4C13/H4C9/H2BC13/H2AC14/MYBL1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES 446 0.3896559 1.613445 0.0000057 0.0001241 0.0001023 2992 NTRK1/SOCS1/ARC/CD274/NCF1/PTPRO/TRIB3/PCSK6/COL6A1/HBEGF/SGK1/BDNF/PRDM1/ATP6V1C2/KL/FGFR4/ATP6V0D2/FGFBP1/NTRK2/FLT1/IL2RG/EREG/NTRK3/FOS/F3/MAPKAPK3/VEGFA/TNS4/FOSB/DOCK3/FGF2/EGR1/APOE/EGR2/ITPR3/MET/GRB10/KITLG/ANOS1/TRIB1/NRP2/HIF1A/MKNK1/FOSL1/MAPK12/KDR/ATP6V0A2/LAMA4/GAB2/DUSP3/IRS2/ASCL1/YAP1/ID3/AP2B1/SPHK1/KLB/DUSP7/SPRED2/MAPK11/THBS1/KRAS/BCAR1/FYN/DUSP6/AXL/SH2B3/MST1R/JUND/NCF2/ADAP1/ITGAV/AP2M1/LAMB3/SPINT2/STAT1/RAC1/RAB4B/AKT3/TGFA/TEC/JUNB/ATP6V1E2/ACTB/GTF2F2/NRAS/FURIN/PTK6/SPP1/AKT1/LAMB1/ADAM17/MYC/NEDD4/DIAPH1/MAPKAPK2/SHC2/ITGA3/SH3GL1/COL5A2/SRC/PRR5/PTPN11/EPS15/PAK2/PTPN12/MAPK13/MAP2K1/EPS15L1/RALA/ITPR2/ACTG1/TIAM1/FGFBP3/GGA3/LAMA3/VAV2/LAMB2/RAP1A/NCF4/DOCK7/CSK/CAV1/IGF2/ESRP2/AP2A2/PTPN3/ELMO2/SPINT1/CRK/CBL
REACTOME_SIGNALING_BY_NTRKS 123 0.5508215 1.989794 0.0000074 0.0001584 0.0001306 2974 NTRK1/ARC/PTPRO/PCSK6/SGK1/BDNF/NTRK2/NTRK3/FOS/F3/MAPKAPK3/FOSB/DOCK3/EGR1/EGR2/TRIB1/FOSL1/MAPK12/DUSP3/IRS2/ASCL1/ID3/AP2B1/DUSP7/MAPK11/KRAS/FYN/DUSP6/JUND/AP2M1/RAC1/JUNB/NRAS/FURIN/MAPKAPK2/SHC2/SRC/PTPN11/MAPK13/MAP2K1/RALA/TIAM1/RAP1A/AP2A2/CRK
REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS 104 -0.5287602 -1.933478 0.0000084 0.0001753 0.0001445 3967 POLR2I/H2BC12/RBBP4/RBBP7/H3-3A/H2AX/RXRA/H3C6/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/HOXA1/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/H3C11/H3C1/HOXB4/PBX1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_SENESCENCE_ASSOCIATED_SECRETORY_PHENOTYPE_SASP 99 -0.5262306 -1.912968 0.0000085 0.0001753 0.0001445 2162 H2BC9/CDKN2C/H3C11/H3C1/CCNA2/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ANAPC4/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/UBE2C/H3C8/H3C2
REACTOME_RHO_GTPASES_ACTIVATE_PKNS 78 -0.5646956 -1.962463 0.0000099 0.0002024 0.0001668 2162 H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/AR/H3C3/CDC25C/H3C8/H3C2
REACTOME_RECOGNITION_AND_ASSOCIATION_OF_DNA_GLYCOSYLASE_WITH_SITE_CONTAINING_AN_AFFECTED_PURINE 46 -0.6384464 -2.023870 0.0000105 0.0002103 0.0001734 3700 H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_HOMOLOGY_DIRECTED_REPAIR 130 -0.4820605 -1.809312 0.0000139 0.0002732 0.0002252 4572 H4C8/RAD50/ATR/LIG3/XRCC1/RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/ERCC4/H2AX/EME1/H2BC6/TIMELESS/H4C5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/WRN/RAD52/H4C6/RAD51B/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CCNA2/CHEK1/DNA2/H2BC11/RPA3/POLE2/H2BC15/BRCA1/H4C4/XRCC2/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/POLQ/H4C13/H4C9/RAD51AP1/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_RHO_GTPASES_ACTIVATE_FORMINS 129 -0.4800147 -1.793853 0.0000144 0.0002780 0.0002291 735 CENPK/DIAPH3/CENPP/KNL1/SGO2/NDC80/MAD2L1/CENPF/CENPE/NUF2/PLK1/SGO1/SKA1/BIRC5/KIF2C/BUB1/ERCC6L/CDC20/BUB1B/SPC25
REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_HSCS 112 -0.5019533 -1.847652 0.0000159 0.0003033 0.0002499 1665 H2BC9/H3C11/H3C1/H2BC11/H3C13/LMO2/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/GATA2/H2BC10/H3C7/MYB/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_BASE_EXCISION_REPAIR_AP_SITE_FORMATION 53 -0.6185152 -2.033968 0.0000177 0.0003313 0.0002731 4574 H2AC8/H4C8/H2AC6/NEIL1/H2BC8/NEIL2/H2BC12/UNG/H2AX/NTHL1/H2BC6/H4C5/H2BC5/H4C12/H2AJ/OGG1/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17/NEIL3
REACTOME_TELOMERE_MAINTENANCE 100 -0.5141976 -1.871398 0.0000195 0.0003590 0.0002959 4152 H2BC8/PRIM1/POLA1/RPA1/POLR2I/H2BC12/RUVBL1/H3-3A/H2AX/H2BC6/H4C5/H2BC5/H4C12/RUVBL2/POLD1/RFC3/WRAP53/H2AJ/WRN/H4C6/H2BC4/H2AZ2/H4C3/H4C2/RFC5/H2BC9/CHTF8/CCNA2/DNA2/H2BC11/RPA3/H2BC15/LIG1/H4C4/H4C1/H2AC4/BLM/POLA2/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/DSCC1/H2BC14/H2BC10/H2BC17
REACTOME_AMYLOID_FIBER_FORMATION 85 -0.5397976 -1.894173 0.0000227 0.0004123 0.0003398 2162 H2BC9/H3C11/H3C1/H2BC11/H3C13/CALB1/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/LTF/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE 20 -0.7733783 -2.048526 0.0000237 0.0004226 0.0003483 871 ANAPC4/CDC14A/CDC20/UBE2C
REACTOME_METABOLISM_OF_STEROIDS 126 0.5279357 1.918570 0.0000317 0.0005580 0.0004598 1035 CYP51A1/MVD/ACAT2/HMGCS1/EBP/FDPS/ELOVL6/LSS/DHCR7/MSMO1/HMGCR/INSIG1/CH25H/HSD17B7/IDI1/SLCO1B1/STARD4/HELZ2/FDFT1/SQLE/SCD/NSDHL/SC5D/STARD5/FASN/SRD5A3/TM7SF2/CYP27B1/MVK/HSD17B12/SLCO1B3
REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING 89 0.5704236 1.983418 0.0000351 0.0006089 0.0005018 2342 NOS2/SOCS1/IL13RA2/ALOX15/MMP1/MAOA/CXCL8/CCL22/CD36/IL2RG/FOS/BCL2/VEGFA/IL1A/FGF2/GATA3/ANXA1/HIF1A/PTGS2/IL23A/ICAM1/TNF/SOCS3/HMOX1/LIF/IL4R/SOX2/ITGAM/PIM1/STAT1/MUC1/JUNB/TIMP1/BATF/CDKN1A/AKT1/RORA/MYC
REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS 85 -0.5342726 -1.874786 0.0000366 0.0006250 0.0005151 918 FBXO5/ANAPC4/CCNB1/PTTG1/CDC14A/MAD2L1/NEK2/PLK1/CDK1/CDC20/UBE2C/BUB1B
REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS 92 -0.5235500 -1.865411 0.0000494 0.0008315 0.0006852 4260 RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/H2AX/H2BC6/TIMELESS/H4C5/RAD9B/ATM/H2BC5/H4C12/RFC3/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/CCNA2/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_CELLULAR_SENESCENCE 181 -0.4193726 -1.668964 0.0000704 0.0011673 0.0009621 2162 H2BC9/CDKN2C/H3C11/TFDP2/H3C1/CCNA2/H2BC11/H3C13/MAP2K6/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/ANAPC4/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/H1-5/H2BC14/H2BC10/LMNB1/H3C7/H1-1/H2BC17/H3C12/CCNE2/H3C3/UBE2C/H3C8/H3C2
REACTOME_MEIOTIC_SYNAPSIS 62 -0.5705567 -1.904949 0.0001058 0.0017307 0.0014264 4574 H2AC8/H4C8/ATR/H2AC6/H2BC8/STAG2/H2BC12/SYCP2/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/SYNE1/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/H2AC4/HSPA2/H2BC7/H2BC3/STAG3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/LMNB1/H2BC17
REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES 65 -0.5501950 -1.849551 0.0001132 0.0018250 0.0015041 3239 SUV39H1/RBBP4/RBBP7/H3C6/H4C5/H4C12/KMT5C/SMYD3/H4C6/EZH2/H4C3/H4C2/DPY30/SMYD2/H3C11/H3C1/H3C13/H4C4/H4C1/H3C10/H4C13/H4C9/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_HDMS_DEMETHYLATE_HISTONES 45 -0.6149784 -1.942451 0.0001160 0.0018445 0.0015202 2521 H4C3/H4C2/H3C11/H3C1/H3C13/H4C4/H4C1/H3C10/H4C13/H4C9/H3C7/H3C12/H3C3/H3C8/H3C2
REACTOME_SIGNALING_BY_NOTCH 217 -0.3967567 -1.603549 0.0001349 0.0021169 0.0017447 2019 NOTCH3/H3C11/TFDP2/DLL1/H3C1/PBX1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/HEY1/H3C10/NBEA/H2BC7/H2BC3/H4C13/HEY2/H4C9/PLXND1/ATP2A3/NEURL1/H2BC13/H2AC14/E2F1/H2BC14/H2BC10/H3C7/H2BC17/H3C12/ST3GAL6/MIR449C/HEYL/H3C3/DLGAP5/H3C8/H3C2
REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION 134 -0.4540423 -1.712717 0.0001427 0.0022086 0.0018202 2866 H4C6/ERBB4/H2BC4/ESR1/H2AZ2/TFF3/H4C3/H4C2/H2BC9/H3C11/H3C1/CXXC5/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/MYB/H2BC17/H3C12/NR5A2/H3C3/H3C8/H3C2
REACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE 58 -0.5750387 -1.902840 0.0001538 0.0023491 0.0019361 3967 H2AC8/H4C8/H2AC6/H2BC8/POLR2I/H2BC12/H3-3A/H2AX/H2BC6/H4C5/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/H2BC9/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H2BC17
REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE 111 -0.4762203 -1.749237 0.0001636 0.0024346 0.0020065 3030 H2AJ/MAPK10/H4C6/H2BC4/H2AZ2/EZH2/H4C3/H4C2/H2BC9/CDKN2C/H3C11/TFDP2/H3C1/H2BC11/H3C13/MAP2K6/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/E2F1/E2F2/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_G2_M_CHECKPOINTS 160 -0.4274524 -1.656697 0.0001622 0.0024346 0.0020065 3582 MCM2/H2BC6/H4C5/RAD9B/ATM/H2BC5/MCM7/H4C12/RFC3/CHEK2/WRN/H4C6/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/CHEK1/DNA2/H2BC11/RPA3/H2BC15/BRCA1/H4C4/H4C1/CDC7/MCM8/PKMYT1/ABRAXAS1/CDC25A/BLM/BRIP1/H2BC7/H2BC3/CCNB1/ORC1/H4C13/H4C9/H2BC13/EXO1/H2BC14/H2BC10/CCNB2/H2BC17/CDK1/MCM10/GTSE1/CDC25C
REACTOME_CHROMATIN_MODIFYING_ENZYMES 255 -0.3805885 -1.552443 0.0001719 0.0025262 0.0020820 4713 RPS2/ENY2/ARID4A/HDAC2/SETD6/NSD3/H2AC8/H4C8/KDM3B/KDM4D/H2AC6/CHD4/EED/PRMT7/H2BC8/H2BC18/MSL3/MCRS1/KDM3A/MORF4L1/SUV39H1/H2BC12/KAT2A/RBBP4/SUDS3/EP400/RUVBL1/RBBP7/ACTL6A/ELP6/H2AX/H3C6/H2BC6/H4C5/SMARCA2/SMARCE1/H2BC5/H4C12/RUVBL2/HAT1/KMT5C/WDR77/H2AJ/SMYD3/SAP30/H4C6/H2BC4/ING4/H2AZ2/EZH2/H4C3/H4C2/JADE1/DPY30/H2BC9/SMYD2/PADI1/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/PADI2/H4C1/H2AC4/H3C10/H2AC16/H2BC7/SMARCD3/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ 63 -0.5518790 -1.855374 0.0001890 0.0027423 0.0022601 3762 TDP1/XRCC4/XRCC5/H4C8/RAD50/H2BC8/H2BC12/TP53BP1/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/H4C6/H2BC4/BARD1/H4C3/H4C2/MRE11/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2BC14/H2BC10/H2BC17
REACTOME_HCMV_EARLY_EVENTS 117 -0.4641200 -1.724741 0.0002180 0.0031243 0.0025749 2260 NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION 24 -0.6913693 -1.913010 0.0002440 0.0034549 0.0028473 1178 CCNA2/PKMYT1/CDC25A/CCNB1/FOXM1/CCNB2/PLK1/CDK1/CDC25C
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION 90 -0.5004047 -1.787646 0.0002726 0.0038135 0.0031429 5794 RPLP0/RPL26L1/RPL17/RPS11/RPL19/RPS16/RPL12/RPL10/RPS28/RPS27A/RPS9/RPS10/RPL27/EEF2/RPL39/RPS19/RPS3/RPSA/RPL41/RPL9/RPL7A/RPL37A/RPS27/RPS2/RPS29/RPS24/EEF1A1/EEF1B2/RPS5/RPS8/RPS15A/RPL36A/RPS21/RPS20/RPL34/RPL13/RPL24/RPS13/RPS12/RPL23A/RPS7/RPS23/RPL27A/RPL3/RPL32/RPL30/RPL29/RPL21/RPL31/RPL14/RPL13A/RPS6/RPL6/RPS14/RPL11/RPL37/RPS25/RPL35A/RPL22/RPL7/RPS18/RPL23/RPL4/RPS4X/RPL10A/RPS4Y1/RPL39L/RPL26/RPL15/RPL5/RPS3A
REACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION 81 -0.5133707 -1.795911 0.0002831 0.0039127 0.0032247 2866 H4C6/H2BC4/H2AZ2/H4C3/H4C2/DPY30/H2BC9/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR 159 -0.4190631 -1.624098 0.0003693 0.0050441 0.0041571 4815 TDP1/RAD51/XRCC4/XRCC5/H4C8/RAD50/ATR/LIG3/XRCC1/RAD9A/TOPBP1/H2BC8/RPA1/H2BC12/RMI1/TP53BP1/ERCC4/H2AX/EME1/H2BC6/TIMELESS/H4C5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/CHEK2/WRN/RAD52/H4C6/RAD51B/H2BC4/BARD1/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CCNA2/CHEK1/DNA2/H2BC11/RPA3/POLE2/H2BC15/BRCA1/H4C4/XRCC2/H4C1/ABRAXAS1/BLM/BRIP1/H2BC7/H2BC3/POLQ/H4C13/H4C9/RAD51AP1/H2BC13/EXO1/H2BC14/H2BC10/H2BC17
REACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE 70 -0.5354568 -1.827494 0.0004090 0.0055214 0.0045504 3961 H2AC8/H4C8/RAD50/CDKN1B/H2AC6/H2BC8/H2BC12/EP400/H1-3/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/H2AJ/H4C6/H2BC4/H2AZ2/H4C3/H4C2/MRE11/H2BC9/CCNA2/H2BC11/H2BC15/H4C4/H4C1/H2AC4/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2AC14/H1-5/H2BC14/H2BC10/LMNB1/H1-1/H2BC17/CCNE2
REACTOME_ION_CHANNEL_TRANSPORT 137 0.4580825 1.674726 0.0004391 0.0058597 0.0048293 1982 ANO1/TRPV6/TRPM6/ATP12A/CASQ2/SLC9B2/SGK1/TTYH2/ANO2/ATP6V1C2/SLC9B1/ATP6V0D2/CLIC2/ANO4/STOM/SCNN1D/FXYD6/RIPK3/ATP11A/ANO8/TRPV3/ATP6V0A2/ATP8B1/ATP13A5/ATP8A2/CLCN6/TRPM4/ANO7/FKBP1B/ATP1B1/TPCN2/MLKL/ATP13A2/ANO9/RYR3/ATP6V1E2
REACTOME_INTERLEUKIN_1_SIGNALING 99 0.4995373 1.738477 0.0005533 0.0072690 0.0059908 5127 IL1R2/NOD2/IL1A/NFKB2/IL1RN/IRAK2/NFKBIA/MYD88/PSMA6/IRAK1/RIPK2/MAP3K8/PSMC4/NFKBIB/SQSTM1/IRAK4/RELA/NOD1/PSMD11/MAP2K1/PSMD7/IKBKG/PSMB2/PSMD3/PELI3/NKIRAS2/PSMB8/PSMD14/PSMC1/TOLLIP/PSMA2/TNIP2/PSMB9/PSMD1/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PELI1/PSMD13/SEM1/PSMB7/PSMD2/SAA1/PSME4/PSMA3
REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING 117 0.4800937 1.719816 0.0005572 0.0072690 0.0059908 5127 RASGRP1/LAT2/PRKCQ/FOS/ITPR3/NFKBIA/CARD11/PSMA6/GAB2/KRAS/FYN/RAC1/TEC/PSMC4/NRAS/BCL10/JUN/RELA/PAK2/PSMD11/ITPR2/SYK/VAV2/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/LYN/MALT1/PSMD1/PLCG1/CDC34/PSMB6/TAB3/PSMD8/PIK3CB/MAPK1/PSME3/MAPK3/TAB2/SHC1/PSME2/GRB2/PSMF1/PSMA7/HRAS/PSMC5/MAPK9/PSMD12/NFKB1/PSMD9/PAK1/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3
REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC 25 0.6937737 1.863579 0.0006125 0.0079018 0.0065123 4292 TAP2/TAP1/SEC23A/SEC13/HLA-F/HLA-C/SEC31A/TAPBP/SEC24D/HLA-G/HLA-A/CALR/SEC24A/HLA-B/SEC24C/HLA-E/HSPA5/ERAP1/PDIA3/ERAP2
REACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING 10 0.8484964 1.858584 0.0008057 0.0102112 0.0084156 1080 CD274/PRDM1/IL2RG/HIF1A
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 175 0.4333897 1.637975 0.0008092 0.0102112 0.0084156 2497 SLC18A2/SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC5A1/SLC39A8/SLC2A6/SLC24A3/SLC5A8/SLC7A11/SLCO4A1/SLCO1B1/SLC6A14/SLC3A2/SLC29A2/SLC7A9/SLC12A2/SLC7A5/SLC7A1/SLC28A3/SLC1A5/SLC5A3/SLC4A9/SLC36A1/SLCO1B3/SLC26A6/SLC26A11/SLC1A4/SLCO3A1/SLC27A4/SLC4A3/SLC38A1/SLCO4C1/AHCYL2/SLC15A3/SLC5A12/SLC12A4/SLC35C1/SLC39A1/SLC16A7/SLC9A1/SLC6A9/SLC17A5/SLC9A4/SLC8A1/SLC8B1/SLC39A4/SLC16A3/SLC39A14/SLC35D2/SLC25A22/SLC35B4/SLC39A7/SLC6A11/SLC29A4/SLC20A2/SLC50A1/RUNX1/SLC9A7
REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 24 0.6969385 1.849807 0.0008416 0.0105070 0.0086594 1486 WARS1/GARS1/MARS1/YARS1/AARS1/TARS1/IARS1/SARS1/EPRS1
REACTOME_DNA_DOUBLE_STRAND_BREAK_RESPONSE 72 -0.5048914 -1.732447 0.0008664 0.0105883 0.0087264 3762 TP53BP1/H2AX/H2BC6/H4C5/ATM/H2BC5/H4C12/CHEK2/H4C6/H2BC4/BARD1/H4C3/H4C2/MRE11/H2BC9/H2BC11/H2BC15/BRCA1/H4C4/H4C1/ABRAXAS1/H2BC7/H2BC3/H4C13/H4C9/H2BC13/H2BC14/H2BC10/H2BC17
REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 109 0.4797223 1.712708 0.0008574 0.0105883 0.0087264 3274 PHOSPHO1/PLA2G3/PNPLA3/ACHE/LPIN1/MFSD2A/PLA2G4C/ABHD4/PLAAT1/LIPH/PLA2G4A/GPCPD1/GPAT3/LPCAT4/GPD2/PISD/PTPMT1/SELENOI/CPNE3/GPAT4/TAFAZZIN/CSNK2B/ACP6/MBOAT1/PLD2/PTDSS1/LPIN2/PITPNM2/PITPNB/LPIN3/ABHD3/OSBPL5/MIGA2/PLA2G15/MGLL/PNPLA2/AGPAT3
REACTOME_CILIUM_ASSEMBLY 184 -0.3809081 -1.512139 0.0008827 0.0106752 0.0087980 3775 CEP57/UNC119B/HAUS1/ARL6/CEP41/TCTN1/HSP90AA1/IFT20/CEP250/TUBA4B/CEP164/CEP43/IQCB1/KIF3A/ARL13B/DYNLT2B/IFT46/BBS10/CEP135/IFT22/ARL3/DYNC2I1/BBS9/CLUAP1/TMEM216/BBIP1/IFT122/IFT43/TCTN2/BBS2/CNTRL/WDR19/CENPJ/KIF17/KIF24/DYNC2LI1/TMEM67/B9D1/PCM1/CEP83/CEP76/CEP97/CCP110/IFT57/IFT140/CEP162/IFT27/CC2D2A/IFT88/IFT52/IFT74/NPHP1/BBS12/CNGA4/CETN2/IFT81/RPGRIP1L/WDR35/IFT172/IFT80/DYNC2H1/MKS1/B9D2/DYNLT2/LZTFL1/CEP78/CEP70/BBS4/DYNLRB2/TTC21B/PRKAR2B/NEK2/PLK1/PLK4/CDK1
REACTOME_SYNTHESIS_OF_PC 25 0.6739735 1.810392 0.0010740 0.0128545 0.0105941 439 PHOSPHO1/ACHE/LPIN1/MFSD2A
REACTOME_TRYPTOPHAN_CATABOLISM 12 0.8131124 1.859454 0.0011985 0.0141985 0.0117017 709 IDO2/KYAT1/HAAO/IDO1/SLC3A2/SLC7A5
REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS 49 0.5925193 1.851894 0.0013214 0.0154969 0.0127718 1907 B3GNT6/GCNT3/MUC21/GALNT4/MUC3A/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ST3GAL4/B3GNT8/MUC1/MUC4
REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION 74 0.5224813 1.763508 0.0013488 0.0156591 0.0129055 6112 RASGRP1/PRKCQ/NFKBIA/CARD11/PSMA6/PSMC4/BCL10/RELA/PSMD11/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/LYN/MALT1/PSMD1/CDC34/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3/PSMA1/UBC/UBE2D2/BTRC/TAB1/PSMC3/TRAF6/IKBKB/UBE2V1/PDPK1
REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS 73 -0.4827062 -1.657787 0.0015438 0.0177459 0.0146254 1585 GSTM2/SULT1E1/GSTM1/UGT1A7/UGT1A5/UGT3A2/SULT1B1/SLC26A1/ACSM1/GSTA3/UGT1A8/NAT1/GSTA4/UGT2A1/GSTA1/GSTA2
REACTOME_INTERLEUKIN_10_SIGNALING 33 0.6524401 1.890235 0.0017235 0.0196176 0.0161679 1546 IL1R2/CXCL10/CCL4/CXCL8/CCL22/IL1A/CD86/IL1RN/PTGS2/CXCL1/ICAM1/TNF/LIF/PTAFR/CCL5/CXCL2
REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 78 0.5137581 1.752965 0.0017550 0.0197823 0.0163036 1831 SLC5A5/SLC26A4/SLC9A3/SLC26A9/SLC24A3/SLC5A8/SLC7A11/SLC6A14/SLC3A2/SLC7A9/SLC12A2/SLC7A5/SLC7A1/SLC1A5/SLC4A9/SLC36A1/SLC26A6/SLC26A11/SLC1A4/SLC4A3/SLC38A1/AHCYL2/SLC15A3/SLC5A12/SLC12A4/SLC9A1/SLC17A5/SLC9A4/SLC8A1/SLC8B1
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 130 -0.4092749 -1.536127 0.0018198 0.0203156 0.0167432 1642 H3C13/KIF19/KIF22/KIF18A/PRKACB/KIF26B/KIF11/H3C10/KIFC1/KIF21A/KIF4A/PRKAR2B/KIF20B/GATA2/H3C7/MYB/H3C12/CENPE/KIF15/KIF2C/KIF20A/H3C3/HBB/KIF18B/H3C8/H3C2
REACTOME_DISEASES_OF_DNA_REPAIR 34 -0.6007858 -1.786260 0.0018579 0.0204501 0.0168540 3602 MUTYH/RAD51/RAD50/NEIL1/RMI1/MSH6/NTHL1/ATM/BRCA2/WRN/OGG1/MSH2/RAD51B/BARD1/MSH3/MRE11/DNA2/BRCA1/XRCC2/BLM/BRIP1/RAD51AP1/EXO1/NEIL3
REACTOME_STIMULI_SENSING_CHANNELS 79 0.5027272 1.720954 0.0018671 0.0204501 0.0168540 1936 ANO1/TRPV6/TRPM6/CASQ2/SLC9B2/SGK1/TTYH2/ANO2/SLC9B1/CLIC2/ANO4/STOM/SCNN1D/RIPK3/ANO8/TRPV3/CLCN6/TRPM4/ANO7/FKBP1B/TPCN2/MLKL/ANO9/RYR3
REACTOME_TRNA_AMINOACYLATION 41 0.5901755 1.795637 0.0019425 0.0208816 0.0172096 1486 WARS1/GARS1/MARS1/YARS1/AARS1/TARS1/IARS1/SARS1/EPRS1
REACTOME_HCMV_INFECTION 141 -0.4072971 -1.552144 0.0019337 0.0208816 0.0172096 2260 NDC1/H2BC9/H2AC15/H3C11/H3C1/H2BC11/H3C13/H2BC15/H4C4/H4C1/H2AC4/H3C10/H2AC16/H2BC7/H2BC3/H4C13/H2AC13/H4C9/H2AC11/H2AC21/H2BC13/H2AC14/H2AC12/H2BC14/H2BC10/H3C7/H2BC17/H3C12/H3C3/H3C8/H3C2
REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE 42 -0.5554177 -1.727075 0.0020411 0.0217401 0.0179172 4547 RAD50/ATR/RAD9A/TOPBP1/RPA1/RMI1/RAD9B/ATM/BRCA2/RFC3/WRN/RAD51B/BARD1/RFC5/MRE11/CHEK1/DNA2/RPA3/BRCA1/XRCC2/BLM/BRIP1/RAD51AP1/EXO1
REACTOME_SIGNALLING_TO_RAS 19 0.7315494 1.847913 0.0021248 0.0224261 0.0184826 2689 NTRK1/MAPKAPK3/MAPK12/MAPK11/KRAS/NRAS/MAPKAPK2/SHC2/SRC/MAPK13/RALA
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 110 -0.4337667 -1.589391 0.0021643 0.0226379 0.0186571 5794 RPLP0/RPL26L1/RPL17/RPS11/RPL19/RPS16/RPL12/RPL10/RPS28/RPS27A/RPS9/RPS10/RPL27/SRP14/RPL39/RPS19/RPS3/RPSA/RPL41/RPL9/RPL7A/RPL37A/RPS27/RPS2/RPS29/RPS24/RPS5/RPS8/RPS15A/RPL36A/RPS21/RPS20/RPL34/RPL13/RPL24/RPS13/RPS12/RPL23A/RPS7/RPS23/RPL27A/RPL3/RPL32/RPL30/RPL29/RPL21/RPL31/RPL14/RPL13A/RPS6/RPL6/RPS14/RPL11/RPL37/RPS25/RPL35A/RPL22/SRP9/RPL7/RPS18/RPL23/RPL4/RPS4X/RPL10A/RPS4Y1/RPL39L/SRPRB/RPL26/RPL15/RPL5/RPS3A
REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA 37 -0.5773343 -1.764814 0.0022149 0.0227569 0.0187552 4801 RAD51/RAD50/ATR/RAD9A/TOPBP1/RPA1/RMI1/ERCC4/RAD9B/ATM/RFC3/WRN/RAD52/BARD1/RFC5/MRE11/ERCC1/DNA2/RPA3/BRCA1/BLM/BRIP1/EXO1
REACTOME_DNA_REPAIR 319 -0.3327307 -1.390761 0.0022071 0.0227569 0.0187552 4094 NEIL2/RPA1/MCRS1/ERCC5/POLR2I/H2BC12/RMI1/UNG/RUVBL1/ACTL6A/TP53BP1/ERCC4/H2AX/EME1/MSH6/NTHL1/H2BC6/TIMELESS/MGMT/H4C5/FANCL/GTF2H5/RAD9B/ATM/BRCA2/H2BC5/H4C12/POLD1/RFC3/ALKBH2/CHEK2/H2AJ/WRN/RAD52/OGG1/MSH2/H4C6/RAD51B/FANCM/H2BC4/BARD1/H2AZ2/MSH3/H4C3/H4C2/RFC5/MRE11/CLSPN/H2BC9/ERCC1/CENPS/CETN2/CCNA2/CHEK1/DNA2/FANCI/H2BC11/RPA3/POLE2/POLI/H2BC15/LIG1/BRCA1/H4C4/XRCC2/UBE2T/H4C1/H2AC4/FANCB/ABRAXAS1/BLM/POLN/BRIP1/H2BC7/H2BC3/INO80B/POLQ/H4C13/FTO/H4C9/CHD1L/RAD51AP1/H2BC13/EXO1/H2AC14/PCLAF/H2BC14/H2BC10/H2BC17/DTL/NEIL3
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION 228 0.3775087 1.475147 0.0022916 0.0233385 0.0192345 2514 CAPN14/EMILIN2/VWF/LOXL4/MMP1/ITGA10/COL6A1/COL13A1/SDC2/KLK7/ADAMTS14/CD44/ADAM8/MMP16/LUM/NID2/CAPN12/TNC/MMP19/SDC3/FGF2/CD47/MMP25/MATN3/ADAM9/PXDN/MMP17/COLGALT2/TIMP2/CEACAM1/ITGB8/KDR/ICAM1/LAMA4/DDR2/ADAMTS9/ITGA9/BMP2/MMP11/THBS1/COL22A1/ITGA6/ITGAM/LOX/COL17A1/SERPINH1/MMP10/ITGAV/LAMB3/PLOD3/COLGALT1/BMP1/COL14A1/LTBP4/ITGB7/TIMP1/ITGB6/FURIN/CAPN2/SPP1/LAMB1/ADAM17/P4HA2/ITGA3/CD151/PLEC/COL5A2/ACTN1
REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS 13 0.7712075 1.801150 0.0025030 0.0250520 0.0206467 2 NTRK1
REACTOME_G0_AND_EARLY_G1 27 -0.6303936 -1.788322 0.0024834 0.0250520 0.0206467 2188 LIN9/TFDP2/CCNA2/CDC25A/E2F1/CCNE2/CDK1/TOP2A/MYBL2
REACTOME_SIGNALLING_TO_ERKS 32 0.6490895 1.873176 0.0026349 0.0261467 0.0215489 4622 NTRK1/MAPKAPK3/MAPK12/MAPK11/KRAS/NRAS/MAPKAPK2/SHC2/SRC/MAPK13/MAP2K1/RALA/RAP1A/CRK/MAP2K2/KIDINS220/MAPK1/RIT1/MAPK3/RALB/SHC1/GRB2/HRAS
REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS 62 0.5277129 1.720474 0.0031192 0.0306895 0.0252929 914 LY6G6C/THY1/RAET1L/LYPD1/PLAUR/NTNG1/RAET1G/ALPL/CEACAM5/LY6K/ULBP2
REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING 126 0.4418600 1.605762 0.0032467 0.0316762 0.0261061 5127 IL1R2/IL1RL1/IL36G/NOD2/IL36A/IL1A/NFKB2/IL1RN/IL18R1/IRAK2/NFKBIA/MYD88/PSMA6/IL1RL2/IRAK1/RIPK2/PTPN9/MAP3K8/PSMC4/NFKBIB/SQSTM1/IRAK4/RELA/PTPN11/NOD1/PSMD11/PTPN12/MAP2K1/ALOX5/PSMD7/IKBKG/PSMB2/PSMD3/PELI3/NKIRAS2/PTPN23/PSMB8/PSMD14/PSMC1/IL18BP/TOLLIP/PSMA2/TNIP2/PSMB9/PTPN18/PSMD1/PSMB6/TAB3/PSMD8/PSME3/TAB2/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PELI1/PSMD13/SEM1/PSMB7/PSMD2/SAA1/PSME4/PSMA3
REACTOME_NICOTINAMIDE_SALVAGING 16 0.7399894 1.788946 0.0033290 0.0322083 0.0265445 3132 SLC5A8/NNMT/PARP9/PTGS2/NAMPT/PARP14/PARP10/PARP6/NAPRT/PARP4
REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION 13 0.7585417 1.771569 0.0034616 0.0329423 0.0271495 9 NOS2
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 53 0.5411698 1.710513 0.0034433 0.0329423 0.0271495 2943 NOD2/AIM2/BCL2/NFKB2/IRAK2/MAPK12/HMOX1/MAPK11/CARD9/TXN/IRAK1/RIPK2/TNFAIP3/RELA/CYLD/NOD1/BIRC3/MAPK13/IKBKG/CASP2
REACTOME_HYALURONAN_METABOLISM 14 0.7566294 1.781890 0.0036892 0.0348227 0.0286992 757 HAS2/HYAL1/CEMIP/CD44/HAS3/HYAL3
REACTOME_RAB_REGULATION_OF_TRAFFICKING 115 0.4459277 1.597028 0.0039039 0.0365520 0.0301245 5503 DENND4A/RIC1/RAB32/RAB8B/RAB31/OPTN/RINL/TBC1D24/DENND5A/AKT3/TBC1D14/RAB9A/RAB35/TBC1D10A/DENND3/AKT1/DENND4C/RAB6A/HPS1/RAB5B/GGA3/RGP1/TBC1D20/TBC1D16/MON1A/RAB3IP/TRAPPC10/CCZ1/TSC1/MAP1LC3B/TRAPPC6A/TBC1D10B/RAB8A/RAB11A/RAB3A/MON1B/RAB21/RABGAP1/ANKRD27/ARF6/RAB5C/RAB7A/TBC1D7/SBF1/CCZ1B/DENND2C/SYTL1/RAB10/TBC1D25/DENND5B/RAB14/RAB18/RAB5A/DENND4B/GGA2/DENND1A/RAB3GAP2/TRAPPC12/SBF2/RAB27A/RAB12/GDI1/RAB1A/RABEP1/TBC1D13/TRAPPC2/ULK1/TRAPPC1/RAB33B/MADD/TRAPPC9
REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION 14 -0.7221659 -1.732056 0.0040090 0.0368576 0.0303763 867 CCNB1/CCNB2/PLK1/CDK1
REACTOME_REGULATION_OF_RUNX2_EXPRESSION_AND_ACTIVITY 69 0.5042976 1.681852 0.0040318 0.0368576 0.0303763 5850 DLX5/PPARGC1B/RUNX2/MSX2/PSMA6/BMP2/STAT1/PSMC4/PSMD11/HIVEP3/PPARGC1A/PSMD7/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/PSMB9/PSMD1/PSMB6/PSMD8/PSME3/PSME2/PSMF1/PSMA7/PSMC5/PSMD12/GSK3B/PSMD9/STUB1/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3/PSMA1/CBFB/UBC/WWP1/TWIST1/ESRRA/PSMC3
REACTOME_BIOLOGICAL_OXIDATIONS 158 -0.3846918 -1.489908 0.0040049 0.0368576 0.0303763 1934 UGT1A4/CYP4B1/CYP27A1/PTGS1/GSTM2/SULT1E1/GSTM1/ALDH2/ADH7/ALDH1A1/UGT1A7/CYP2C8/UGT1A5/UGT3A2/CYP2W1/FMO3/SULT1B1/CYP4F3/CYP39A1/MTARC1/SLC26A1/ACSM1/ACSS1/GSTA3/POMC/EPHX1/CYP24A1/DPEP2/CYP2B6/UGT1A8/NAT1/CYP2F1/ADH6/CYP4A22/FMO2/CYP2A6/ALDH3A1/GSTA4/CYP26B1/UGT2A1/GSTA1/GSTA2
REACTOME_METALLOPROTEASE_DUBS 30 -0.5918390 -1.718189 0.0041518 0.0376580 0.0310360 2089 STAMBPL1/BARD1/H2AC15/BRCA1/H2AC4/ABRAXAS1/H2AC16/H2AC13/H2AC11/H2AC21/H2AC14/H2AC12
REACTOME_BASIGIN_INTERACTIONS 20 0.6926358 1.770445 0.0042623 0.0380153 0.0313304 2847 MMP1/SLC7A11/SLC3A2/SLC7A9/SLC7A5/ITGA6/ATP1B1/SLC16A3/ITGA3/CAV1
REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 80 0.4940431 1.699162 0.0042894 0.0380153 0.0313304 2634 MX2/ISG15/OAS3/OASL/OAS1/MX1/IFIT1/USP18/OAS2/UBE2L6/HERC5/STAT1/EIF2AK2/TRIM25/NUP188/EIF4E3/SEC13/NEDD4/EIF4G1/PDE12
REACTOME_PHOSPHOLIPID_METABOLISM 185 0.3974143 1.510926 0.0042298 0.0380153 0.0313304 4865 PHOSPHO1/PLA2G3/PNPLA3/ACHE/LPIN1/MFSD2A/PLA2G4C/ABHD4/ENPP6/PLAAT1/LIPH/PLA2G4A/GPCPD1/GPAT3/LPCAT4/GPD2/PISD/PLEKHA6/PTPMT1/SELENOI/CPNE3/PLEKHA2/GPAT4/PIP4K2A/TAFAZZIN/CSNK2B/ACP6/GDPD3/PIP5K1A/MBOAT1/PIK3C2B/PLD2/MTMR12/INPPL1/PTDSS1/PIP4P1/LPIN2/PITPNM2/PITPNB/LPIN3/ABHD3/OSBPL5/INPP5J/MIGA2/PIP4K2C/PLA2G15/PI4K2A/MGLL/ARF3/INPP5F/PLEKHA5/PNPLA2/AGPAT3/INPP5D/CPNE1/PIP5K1C/SYNJ1/HADHA/PIK3CB/SBF1/LPCAT1/DGAT1/PLAAT3/RAB14/MBOAT7/SYNJ2/OCRL/PCYT2/GDE1/RAB5A/OSBPL8/PLEKHA1/PCYT1A/CSNK2A2/DDHD2/STARD10/ARF1/PIKFYVE/INPP5K/PNPLA6/AGPAT2/PNPLA8/CSNK2A1/SBF2/PI4KB
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE 69 0.4996181 1.666245 0.0043886 0.0385996 0.0318120 1281 SPRR2E/RPTN/SPRR3/SPRR2F/SPRR2A/KRT16/PCSK6/SPRR1A/KRT23/KRT24/SPRR2D/KRT40/CSTA/KLK12/KRT6A/KRT78/PI3/LCE1E/KRT8/PKP2/KRT18/PRSS8
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION 147 -0.3890603 -1.490909 0.0044521 0.0388641 0.0320300 2188 LIN9/CDKN2C/TFDP2/CCNA2/TK1/DHFR/RPA3/POLE2/CDC7/MCM8/TYMS/CDC25A/POLA2/FBXO5/CCNB1/ORC1/E2F1/E2F2/CDT1/GMNN/CCNE2/CDK1/RRM2/MCM10/TOP2A/MYBL2
REACTOME_O_LINKED_GLYCOSYLATION 85 0.4765247 1.658298 0.0045608 0.0395158 0.0325671 1907 B3GNT6/GCNT3/THSD7A/MUC21/ADAMTS14/GALNT4/MUC3A/ST6GAL1/GALNT7/GCNT4/GALNT10/GALNT6/GALNT5/ADAMTSL3/ADAMTS9/ADAMTS17/ST3GAL4/THBS1/B3GNT8/MUC1/MUC4
REACTOME_RESPONSE_OF_EIF2AK1_HRI_TO_HEME_DEFICIENCY 15 0.7556324 1.795113 0.0046385 0.0396281 0.0326596 2725 TRIB3/CHAC1/ASNS/DDIT3/ATF4/GRB10/CEBPG/ATF3/EIF2S2/ATF5
REACTOME_PEPTIDE_HORMONE_METABOLISM 53 0.5316861 1.680537 0.0046762 0.0396281 0.0326596 949 DPP4/INHBE/ACHE/MME/KLF4/PAX6/ACE/ANPEP/PLA2G7/STX1A
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 79 0.4790959 1.640059 0.0046645 0.0396281 0.0326596 5127 RASGRP1/NFKBIA/CARD11/PSMA6/KRAS/NFKBIE/PSMC4/NRAS/NFKBIB/BCL10/RELA/PSMD11/PSMD7/IKBKG/PSMB2/PSMD3/PSMB8/PSMD14/PSMC1/PSMA2/FKBP1A/PPIA/PSMB9/MALT1/PSMD1/PSMB6/PSMD8/PSME3/RASGRP3/PSME2/PSMF1/PSMA7/HRAS/PSMC5/PSMD12/NFKB1/PSMD9/CHUK/PSMD13/SEM1/PSMB7/PSMD2/PSME4/PSMA3
REACTOME_NGF_STIMULATED_TRANSCRIPTION 36 0.6105726 1.808003 0.0048102 0.0404688 0.0333525 1941 ARC/SGK1/FOS/F3/FOSB/EGR1/EGR2/TRIB1/FOSL1/ASCL1/ID3/JUND/JUNB
REACTOME_SIGNALING_BY_VEGF 99 0.4545217 1.581815 0.0050038 0.0417942 0.0344448 4007 NCF1/TRIB3/FLT1/MAPKAPK3/VEGFA/ITPR3/NRP2/MAPK12/KDR/SPHK1/MAPK11/KRAS/BCAR1/FYN/AXL/NCF2/ITGAV/RAC1/AKT3/ACTB/NRAS/AKT1/MAPKAPK2/SHC2/SRC/PRR5/PAK2/MAPK13/ITPR2/ACTG1/VAV2/NCF4/CAV1/ELMO2/CRK/WASF1/VEGFD/PRKCA/NCKAP1/JUP/PLCG1/ABI1/MTOR/PIK3CB/CYFIP1/CTNNA1
REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE 14 0.7439570 1.752046 0.0051219 0.0424751 0.0350060 1466 SLC18A2/MAOA/STX1A/PPFIA3/SYT1
REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1 10 0.7907963 1.732195 0.0052550 0.0432699 0.0356610 351 DPP4/PAX6
REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES 11 -0.7473337 -1.671638 0.0056947 0.0465606 0.0383731 2332 SMC4/SMC2/CCNB1/CCNB2/NCAPH/CDK1/NCAPG
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 29 -0.5668830 -1.623894 0.0060854 0.0494068 0.0407188 2188 LIN9/TFDP2/TK1/DHFR/TYMS/CDC25A/FBXO5/ORC1/E2F1/CDT1/CDK1/RRM2 
## R version 4.3.1 (2023-06-16 ucrt)
## Platform: x86_64-w64-mingw32/x64 (64-bit)
## Running under: Windows 10 x64 (build 19045)
## 
## Matrix products: default
## 
## 
## locale:
## [1] LC_COLLATE=English_United States.utf8 
## [2] LC_CTYPE=English_United States.utf8   
## [3] LC_MONETARY=English_United States.utf8
## [4] LC_NUMERIC=C                          
## [5] LC_TIME=English_United States.utf8    
## 
## time zone: America/Los_Angeles
## tzcode source: internal
## 
## attached base packages:
## [1] grid      stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] ggvenn_0.1.10               kableExtra_1.4.0           
##  [3] clusterProfiler_4.8.3       msigdbr_7.5.1              
##  [5] xlsx_0.6.5                  pheatmap_1.0.12            
##  [7] ggrepel_0.9.5               biomaRt_2.56.1             
##  [9] cowplot_1.1.3               lubridate_1.9.2            
## [11] forcats_1.0.0               stringr_1.5.1              
## [13] dplyr_1.1.4                 purrr_1.0.2                
## [15] readr_2.1.4                 tidyr_1.3.1                
## [17] tibble_3.2.1                ggplot2_3.5.0              
## [19] tidyverse_2.0.0             DESeq2_1.40.2              
## [21] SummarizedExperiment_1.30.2 Biobase_2.60.0             
## [23] MatrixGenerics_1.12.3       matrixStats_1.2.0          
## [25] GenomicRanges_1.52.0        GenomeInfoDb_1.36.3        
## [27] IRanges_2.34.1              S4Vectors_0.38.2           
## [29] BiocGenerics_0.46.0         RColorBrewer_1.1-3         
## 
## loaded via a namespace (and not attached):
##   [1] rstudioapi_0.15.0       jsonlite_1.8.8          magrittr_2.0.3         
##   [4] farver_2.1.1            rmarkdown_2.26          ragg_1.2.5             
##   [7] fs_1.6.3                zlibbioc_1.46.0         vctrs_0.6.5            
##  [10] memoise_2.0.1           RCurl_1.98-1.12         ggtree_3.8.2           
##  [13] htmltools_0.5.6         S4Arrays_1.0.6          progress_1.2.2         
##  [16] curl_5.2.1              gridGraphics_0.5-1      sass_0.4.9             
##  [19] bslib_0.5.1             plyr_1.8.9              cachem_1.0.8           
##  [22] igraph_2.0.3            lifecycle_1.0.4         pkgconfig_2.0.3        
##  [25] gson_0.1.0              Matrix_1.6-5            R6_2.5.1               
##  [28] fastmap_1.1.1           GenomeInfoDbData_1.2.10 aplot_0.2.2            
##  [31] digest_0.6.33           enrichplot_1.20.3       colorspace_2.1-0       
##  [34] patchwork_1.2.0         AnnotationDbi_1.62.2    textshaping_0.3.6      
##  [37] RSQLite_2.3.1           labeling_0.4.3          filelock_1.0.2         
##  [40] fansi_1.0.6             timechange_0.2.0        httr_1.4.7             
##  [43] polyclip_1.10-6         abind_1.4-5             compiler_4.3.1         
##  [46] bit64_4.0.5             withr_3.0.0             downloader_0.4         
##  [49] BiocParallel_1.34.2     viridis_0.6.4           DBI_1.1.3              
##  [52] highr_0.10              ggforce_0.4.1           MASS_7.3-60            
##  [55] rappdirs_0.3.3          DelayedArray_0.26.7     HDO.db_0.99.1          
##  [58] tools_4.3.1             scatterpie_0.2.1        ape_5.7-1              
##  [61] glue_1.7.0              nlme_3.1-162            GOSemSim_2.26.1        
##  [64] shadowtext_0.1.2        reshape2_1.4.4          fgsea_1.26.0           
##  [67] generics_0.1.3          gtable_0.3.4            tzdb_0.4.0             
##  [70] data.table_1.15.4       hms_1.1.3               tidygraph_1.2.3        
##  [73] xml2_1.3.5              utf8_1.2.4              XVector_0.40.0         
##  [76] pillar_1.9.0            yulab.utils_0.1.0       babelgene_22.9         
##  [79] rJava_1.0-6             splines_4.3.1           tweenr_2.0.2           
##  [82] treeio_1.24.3           BiocFileCache_2.8.0     lattice_0.21-8         
##  [85] bit_4.0.5               tidyselect_1.2.1        GO.db_3.17.0           
##  [88] locfit_1.5-9.8          Biostrings_2.68.1       knitr_1.44             
##  [91] gridExtra_2.3           svglite_2.1.2           xfun_0.40              
##  [94] graphlayouts_1.0.1      stringi_1.8.3           lazyeval_0.2.2         
##  [97] ggfun_0.1.3             yaml_2.3.7              evaluate_0.23          
## [100] codetools_0.2-19        xlsxjars_0.6.1          ggraph_2.1.0           
## [103] qvalue_2.32.0           ggplotify_0.1.2         cli_3.6.1              
## [106] systemfonts_1.0.4       munsell_0.5.1           jquerylib_0.1.4        
## [109] Rcpp_1.0.11             dbplyr_2.3.3            png_0.1-8              
## [112] XML_3.99-0.14           parallel_4.3.1          blob_1.2.4             
## [115] prettyunits_1.2.0       DOSE_3.26.2             bitops_1.0-7           
## [118] tidytree_0.4.5          viridisLite_0.4.2       scales_1.3.0           
## [121] crayon_1.5.2            rlang_1.1.1             fastmatch_1.1-4        
## [124] KEGGREST_1.40.0